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SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-06 08 2006-16 20 20 20
White 1975-07 08 2007-16 20 20 20
Black 1975-96 13 1996-00 -24 2000-16 19 19 19
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-07 06 2007-10 41 2010-16 10 20 10
White 2000-07 04 2007-10 39 2010-16 11 20 11
White NHef 2000-07 05 2007-10 40 2010-16 11 20 11
Black 2000-16 20 20 20
Black NHef 2000-16 20 20 20
APIe 2000-16 14 14 14
AIANeg 2000-16 09 09 09
Hispanicf 2000-16 10 10 10
US Cancer Mortalityc 1975-2016
All Races 1975-94 14 1994-02 -07 2002-09 -19 2009-12 10 2012-16 -12 -06 -12
White 1975-94 14 1994-02 -05 2002-09 -19 2009-12 10 2012-16 -12 -06 -12
Black 1975-82 35 1982-96 12 1996-09 -18 2009-16 -02 -06 -02
US Cancer Mortalityc 2000-2016
All Races 2000-09 -18 2009-12 08 2012-16 -12 -06 -12
White 2000-02 00 2002-09 -20 2009-12 11 2012-16 -12 -06 -12
White NHef 2000-02 00 2002-09 -20 2009-12 11 2012-16 -12 -06 -12
Black 2000-09 -19 2009-16 -01 -05 -01
Black NHef 2000-09 -18 2009-16 -01 -05 -01
APIe 2000-16 -05 -05 -05
AIANeg 2000-16 -18 -18 -18
Hispanicf 2000-16 -10 -10 -10
Table 181
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Both Sexes by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-06 08 2006-16 20 20 20
White 1975-16 10 10 10
Black 1975-16 10 10 10
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-06 06 2006-12 29 2012-16 02 17 02
White 2000-06 03 2006-12 28 2012-16 02 16 02
White NHef 2000-06 05 2006-11 30 2011-16 08 18 08
Black 2000-16 19 19 19
Black NHef 2000-16 19 19 19
APIe 2000-16 23 23 23
AIANeg 2000-16 24 24 24
Hispanicf 2000-07 -15 2007-12 42 2012-16 -19 15 -19
US Cancer Mortalityc 1975-2016
All Races 1975-94 14 1994-16 -09 -09 -09
White 1975-94 15 1994-16 -08 -08 -08
Black 1975-91 23 1991-16 -12 -12 -12
US Cancer Mortalityc 2000-2016
All Races 2000-16 -09 -09 -09
White 2000-16 -08 -08 -08
White NHef 2000-16 -08 -08 -08
Black 2000-16 -11 -11 -11
Black NHef 2000-16 -10 -10 -10
APIe 2000-16 03 03 03
AIANeg 2000-16 -19 -19 -19
Hispanicf 2000-16 -07 -07 -07
Table 182
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Males by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-07 06 2007-16 20 20 20
White 1975-16 07 07 07
Black 1975-16 11 11 11
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-07 02 2007-10 40 2010-16 11 20 11
White 2000-16 14 14 14
White NHef 2000-03 -16 2003-16 17 17 17
Black 2000-16 19 19 19
Black NHef 2000-16 19 19 19
APIe 2000-16 04 04 04
AIANeg 2000-16 -04 -04 -04
Hispanicf 2000-16 09 09 09
US Cancer Mortalityc 1975-2016
All Races 1975-93 15 1993-02 -05 2002-09 -27 2009-12 18 2012-16 -17 -08 -17
White 1975-93 14 1993-02 -05 2002-08 -26 2008-16 -04 -07 -04
Black 1975-93 21 1993-00 -01 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
US Cancer Mortalityc 2000-2016
All Races 2000-09 -24 2009-12 15 2012-16 -17 -08 -17
White 2000-08 -24 2008-16 -05 -07 -05
White NHef 2000-08 -24 2008-16 -04 -07 -04
Black 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
Black NHef 2000-09 -27 2009-13 28 2013-16 -37 -07 -22
APIe 2000-16 -14 -14 -14
AIANeg 2000-16 -16 -16 -16
Hispanicf 2000-16 -14 -14 -14
Table 183
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 651 805 537 594 750 477 1470 1815 12742009 674 853 535 612 792 472 1460 1732 12672010 695 872 556 639 809 502 1494 1944 11962011 724 886 594 663 831 526 1509 1728 13702012 702 898 548 636 828 480 1550 1983 12572013 727 921 573 666 877 493 1472 1776 12722014 712 900 561 651 847 489 1453 1687 12942015 760 939 620 699 883 553 1456 1674 12922016 757 937 612 695 884 543 1582 1828 1384
Table 184Myeloma
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-2016 600 750 490 553 707 440 1252 1498 10871975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 647 801 534 591 746 474 1459 1801 12662009 666 844 529 605 783 467 1438 1707 12472010 684 859 547 628 797 494 1460 1899 11692011 709 868 582 649 813 514 1463 1675 13292012 684 874 533 619 806 468 1492 1910 12102013 703 892 554 644 847 477 1403 1693 12142014 682 861 538 623 810 468 1370 1589 12222015 717 886 584 659 832 520 1353 1552 12022016 698 865 565 640 814 500 1426 1650 1247
Table 185Myeloma
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-06 08 2006-16 20 20 20
White 1975-16 10 10 10
Black 1975-16 10 10 10
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-06 06 2006-12 29 2012-16 02 17 02
White 2000-06 03 2006-12 28 2012-16 02 16 02
White NHef 2000-06 05 2006-11 30 2011-16 08 18 08
Black 2000-16 19 19 19
Black NHef 2000-16 19 19 19
APIe 2000-16 23 23 23
AIANeg 2000-16 24 24 24
Hispanicf 2000-07 -15 2007-12 42 2012-16 -19 15 -19
US Cancer Mortalityc 1975-2016
All Races 1975-94 14 1994-16 -09 -09 -09
White 1975-94 15 1994-16 -08 -08 -08
Black 1975-91 23 1991-16 -12 -12 -12
US Cancer Mortalityc 2000-2016
All Races 2000-16 -09 -09 -09
White 2000-16 -08 -08 -08
White NHef 2000-16 -08 -08 -08
Black 2000-16 -11 -11 -11
Black NHef 2000-16 -10 -10 -10
APIe 2000-16 03 03 03
AIANeg 2000-16 -19 -19 -19
Hispanicf 2000-16 -07 -07 -07
Table 182
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Males by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-07 06 2007-16 20 20 20
White 1975-16 07 07 07
Black 1975-16 11 11 11
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-07 02 2007-10 40 2010-16 11 20 11
White 2000-16 14 14 14
White NHef 2000-03 -16 2003-16 17 17 17
Black 2000-16 19 19 19
Black NHef 2000-16 19 19 19
APIe 2000-16 04 04 04
AIANeg 2000-16 -04 -04 -04
Hispanicf 2000-16 09 09 09
US Cancer Mortalityc 1975-2016
All Races 1975-93 15 1993-02 -05 2002-09 -27 2009-12 18 2012-16 -17 -08 -17
White 1975-93 14 1993-02 -05 2002-08 -26 2008-16 -04 -07 -04
Black 1975-93 21 1993-00 -01 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
US Cancer Mortalityc 2000-2016
All Races 2000-09 -24 2009-12 15 2012-16 -17 -08 -17
White 2000-08 -24 2008-16 -05 -07 -05
White NHef 2000-08 -24 2008-16 -04 -07 -04
Black 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
Black NHef 2000-09 -27 2009-13 28 2013-16 -37 -07 -22
APIe 2000-16 -14 -14 -14
AIANeg 2000-16 -16 -16 -16
Hispanicf 2000-16 -14 -14 -14
Table 183
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 651 805 537 594 750 477 1470 1815 12742009 674 853 535 612 792 472 1460 1732 12672010 695 872 556 639 809 502 1494 1944 11962011 724 886 594 663 831 526 1509 1728 13702012 702 898 548 636 828 480 1550 1983 12572013 727 921 573 666 877 493 1472 1776 12722014 712 900 561 651 847 489 1453 1687 12942015 760 939 620 699 883 553 1456 1674 12922016 757 937 612 695 884 543 1582 1828 1384
Table 184Myeloma
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-2016 600 750 490 553 707 440 1252 1498 10871975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 647 801 534 591 746 474 1459 1801 12662009 666 844 529 605 783 467 1438 1707 12472010 684 859 547 628 797 494 1460 1899 11692011 709 868 582 649 813 514 1463 1675 13292012 684 874 533 619 806 468 1492 1910 12102013 703 892 554 644 847 477 1403 1693 12142014 682 861 538 623 810 468 1370 1589 12222015 717 886 584 659 832 520 1353 1552 12022016 698 865 565 640 814 500 1426 1650 1247
Table 185Myeloma
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
SEER 9 Delay-Adjusted Incidencea 1975-2016
All Races 1975-07 06 2007-16 20 20 20
White 1975-16 07 07 07
Black 1975-16 11 11 11
SEER 21 Delay-Adjusted Incidenceb 2000-2016
All Races 2000-07 02 2007-10 40 2010-16 11 20 11
White 2000-16 14 14 14
White NHef 2000-03 -16 2003-16 17 17 17
Black 2000-16 19 19 19
Black NHef 2000-16 19 19 19
APIe 2000-16 04 04 04
AIANeg 2000-16 -04 -04 -04
Hispanicf 2000-16 09 09 09
US Cancer Mortalityc 1975-2016
All Races 1975-93 15 1993-02 -05 2002-09 -27 2009-12 18 2012-16 -17 -08 -17
White 1975-93 14 1993-02 -05 2002-08 -26 2008-16 -04 -07 -04
Black 1975-93 21 1993-00 -01 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
US Cancer Mortalityc 2000-2016
All Races 2000-09 -24 2009-12 15 2012-16 -17 -08 -17
White 2000-08 -24 2008-16 -05 -07 -05
White NHef 2000-08 -24 2008-16 -04 -07 -04
Black 2000-09 -28 2009-13 27 2013-16 -37 -07 -22
Black NHef 2000-09 -27 2009-13 28 2013-16 -37 -07 -22
APIe 2000-16 -14 -14 -14
AIANeg 2000-16 -16 -16 -16
Hispanicf 2000-16 -14 -14 -14
Table 183
Myeloma
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 651 805 537 594 750 477 1470 1815 12742009 674 853 535 612 792 472 1460 1732 12672010 695 872 556 639 809 502 1494 1944 11962011 724 886 594 663 831 526 1509 1728 13702012 702 898 548 636 828 480 1550 1983 12572013 727 921 573 666 877 493 1472 1776 12722014 712 900 561 651 847 489 1453 1687 12942015 760 939 620 699 883 553 1456 1674 12922016 757 937 612 695 884 543 1582 1828 1384
Table 184Myeloma
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-2016 600 750 490 553 707 440 1252 1498 10871975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 647 801 534 591 746 474 1459 1801 12662009 666 844 529 605 783 467 1438 1707 12472010 684 859 547 628 797 494 1460 1899 11692011 709 868 582 649 813 514 1463 1675 13292012 684 874 533 619 806 468 1492 1910 12102013 703 892 554 644 847 477 1403 1693 12142014 682 861 538 623 810 468 1370 1589 12222015 717 886 584 659 832 520 1353 1552 12022016 698 865 565 640 814 500 1426 1650 1247
Table 185Myeloma
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 651 805 537 594 750 477 1470 1815 12742009 674 853 535 612 792 472 1460 1732 12672010 695 872 556 639 809 502 1494 1944 11962011 724 886 594 663 831 526 1509 1728 13702012 702 898 548 636 828 480 1550 1983 12572013 727 921 573 666 877 493 1472 1776 12722014 712 900 561 651 847 489 1453 1687 12942015 760 939 620 699 883 553 1456 1674 12922016 757 937 612 695 884 543 1582 1828 1384
Table 184Myeloma
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-2016 600 750 490 553 707 440 1252 1498 10871975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 647 801 534 591 746 474 1459 1801 12662009 666 844 529 605 783 467 1438 1707 12472010 684 859 547 628 797 494 1460 1899 11692011 709 868 582 649 813 514 1463 1675 13292012 684 874 533 619 806 468 1492 1910 12102013 703 892 554 644 847 477 1403 1693 12142014 682 861 538 623 810 468 1370 1589 12222015 717 886 584 659 832 520 1353 1552 12022016 698 865 565 640 814 500 1426 1650 1247
Table 185Myeloma
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Diagnosis1975-2016 600 750 490 553 707 440 1252 1498 10871975-1979 493 616 409 463 582 384 977 1194 8261980 479 577 412 443 544 375 989 1083 9051981 503 602 433 462 546 400 1101 1523 8191982 529 628 467 489 587 432 1157 1393 9721983 531 694 422 474 630 372 1378 1635 11921984 541 697 433 505 644 410 1079 1523 7711985 521 633 436 494 596 418 945 1258 7241986 534 631 466 489 602 413 1101 1157 10421987 593 737 502 566 718 471 1113 1348 9691988 533 656 451 503 637 418 1081 1206 9811989 544 672 450 510 634 418 1078 1357 8941990 567 726 459 526 695 410 1212 1462 10571991 605 769 486 558 720 441 1278 1591 10641992 596 731 506 563 701 475 1157 1329 10311993 560 734 433 514 683 395 1279 1569 10611994 574 680 506 521 632 447 1292 1535 12011995 576 725 474 534 680 434 1231 1524 10461996 584 720 481 543 689 429 1273 1351 12131997 615 740 529 574 708 479 1275 1442 12021998 599 737 495 562 714 446 1215 1344 11341999 565 712 458 518 661 413 1219 1546 10152000 616 767 504 587 767 452 1116 1095 11072001 596 738 487 552 695 441 1244 1518 10792002 608 792 471 572 768 426 1127 1409 9482003 594 740 486 566 719 450 1122 1429 9262004 600 754 485 551 706 435 1303 1620 10832005 627 789 507 585 758 453 1284 1473 11672006 603 727 510 562 696 456 1330 1500 12242007 614 803 468 573 778 411 1224 1486 10442008 647 801 534 591 746 474 1459 1801 12662009 666 844 529 605 783 467 1438 1707 12472010 684 859 547 628 797 494 1460 1899 11692011 709 868 582 649 813 514 1463 1675 13292012 684 874 533 619 806 468 1492 1910 12102013 703 892 554 644 847 477 1403 1693 12142014 682 861 538 623 810 468 1370 1589 12222015 717 886 584 659 832 520 1353 1552 12022016 698 865 565 640 814 500 1426 1650 1247
Table 185Myeloma
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Year of Death1975-2016 355 445 293 328 417 267 672 823 5761975-1979 312 392 259 291 366 240 561 701 4661980 327 412 272 302 383 249 610 737 5231981 329 405 279 301 370 254 657 816 5501982 338 417 285 310 381 262 668 856 5451983 344 434 287 315 397 263 682 873 5581984 347 426 295 320 392 273 664 838 5471985 358 446 302 329 411 278 690 857 5821986 361 451 303 329 412 276 716 910 5951987 361 457 297 332 421 272 706 918 5711988 363 461 302 336 435 273 689 814 6121989 370 464 310 342 430 285 708 891 5921990 380 483 313 349 445 287 732 964 5921991 387 483 326 354 446 295 777 959 6641992 380 472 319 348 436 290 745 933 6321993 396 489 335 364 456 304 782 932 6881994 397 503 326 367 469 299 768 968 6461995 398 494 336 366 461 302 779 941 6901996 391 494 325 359 460 294 770 963 6541997 390 493 322 360 461 293 749 924 6451998 383 476 321 350 441 288 775 949 6771999 384 472 324 352 441 291 745 884 6642000 383 466 327 353 438 296 751 876 6732001 380 469 318 353 441 290 723 874 6292002 381 478 315 357 456 287 689 833 6032003 372 461 309 345 436 280 714 844 6322004 358 443 298 332 416 271 688 831 6042005 358 451 291 334 426 267 648 806 5502006 350 438 287 325 411 263 654 828 5462007 349 442 283 323 418 255 658 785 5842008 333 429 262 308 403 238 634 797 5302009 329 423 261 308 399 240 596 761 4882010 332 416 270 306 389 245 637 780 5482011 338 427 272 316 407 248 608 738 5252012 340 425 277 317 403 251 627 741 5542013 332 418 267 308 396 240 637 744 5702014 334 421 268 308 398 240 645 771 5622015 330 418 263 307 398 237 603 732 5232016 322 406 258 300 384 235 596 728 510
Table 186Myeloma
Age-adjusted US Deatha Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 69 87 56 63 81 49 137 163 119Under 65 27 31 22 23 28 19 56 63 5065 and over 363 469 285 337 447 255 694 853 595
All ages (WHO world std)c 50 62 40 45 57 35 100 118 87
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 - - - - - - - -25-29 01 01 01 01 01 - - - -30-34 04 05 03 03 03 03 09 11 0835-39 10 11 08 08 10 07 19 21 1740-44 22 25 19 18 22 15 55 61 4945-49 43 48 39 37 43 32 92 99 8650-54 75 87 64 65 77 54 153 168 14055-59 118 139 98 104 125 83 240 268 21660-64 179 217 143 159 197 124 364 432 31065-69 265 323 213 238 294 187 559 690 46070-74 344 427 275 316 403 240 678 789 60075-79 427 552 330 394 522 293 822 997 70980-84 473 626 366 453 608 343 841 1098 69985+ 379 555 288 370 559 272 637 814 563
US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 33 42 27 31 40 24 62 74 54Under 65 07 09 06 06 08 05 15 17 1365 and over 213 270 172 201 260 158 387 467 340
All ages (WHO world std)c 18 22 14 16 21 13 35 41 30
Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 00 00 - 00 00 - - - -35-39 01 02 01 01 01 01 03 04 0240-44 04 05 03 03 04 02 07 07 0745-49 09 11 07 07 09 05 20 23 1750-54 19 23 14 16 20 12 40 47 3455-59 33 41 26 29 36 22 70 84 5960-64 61 73 49 54 66 42 125 145 10865-69 102 124 82 93 114 73 209 251 17770-74 163 201 131 151 190 117 318 378 27575-79 240 298 194 227 288 178 422 492 37780-84 337 425 276 322 413 257 600 704 54185+ 372 509 300 359 501 284 618 808 540
Table 187Myeloma
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 12 13 10 - - -1970-1973a - - - 19 20 17 - - -1975-1977b 246 239 253 241 236 247 293 289 2951978-1980b 259 244 275 248 241 255 325 274 3751981-1983b 275 257 294 272 254 289 289 296 2791984-1986b 273 277 268 260 258 262 318 333 3031987-1989b 272 288 256 268 291 245 300 293 3061990-1992b 293 306 279 284 297 269 342 380 3061993-1995b 317 323 310 305 314 295 354 349 3571996-1998b 325 345 304 323 344 299 316 329 3061999-2001b 346 370 319 345 370 315 344 372 3202002-2004b 426 436 414 434 448 416 407 408 4072005-2008b 475 478 471 471 483 454 495 458 5272009-2015b 537f 544f 529f 532f 541f 520f 551f 548f 554f
5-Year Period Survival (Percent)cd
2015 530 525 536 518 513 524 550 546 554
Stage Distribution () 2009-2015ce
All StagesNumber of cases 34220 18885 15335 24646 14089 10557 6936 3364 3572Percent 100 100 100 100 100 100 100 100 100Localized 5 5 4 5 6 5 4 4 3Regional 0 0 0 0 0 0 0 0 0Distant 95 95 96 95 94 95 96 96 97UnstagedUnknown 0 0 0 0 0 0 0 0 0
5-Year Relative Survival (Percent) 2009-2015c
Age at DiagnosisAges lt45 762 742 793 766 751 791 734 693 781Ages 45-54 662 645 684 664 647 687 654 632 674Ages 55-64 602 587 623 608 597 624 583 552 613Ages 65-74 534 529 540 532 521 548 523 537 509Ages 75+ 329 331 328 322 325 318 341 329 348Ages lt65 636 620 658 639 626 658 622 593 651Ages 65+ 435 440 430 428 430 425 446 461 435
StageeAll Stages 522 521 524 513 513 513 539 534 544Localized 739 737 739 739 740 736 714 710g 715g
Regional - - - - - - - - -Distant 511 508 514 501 500 502 532 526 538UnstagedUnknown - - - - - - - - -
Table 188Myeloma
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 680 695 723 719 740 705 743 750 737 725 727 736 773 748 762 742 772 779 821 814 799 816 815 831 8192-year 521 545 576 574 587 575 606 624 599 600 599 629 651 665 649 664 668 690 728 721 718 736 724 7513-year 396 428 453 462 478 449 487 512 480 500 496 535 559 587 576 583 581 618 654 655 650 666 6634-year 315 342 357 369 401 381 387 400 391 413 442 469 479 509 509 513 507 559 597 589 580 6015-year 251 269 275 299 333 318 314 343 315 346 376 400 422 455 467 463 465 503 529 532 5116-year 201 210 221 245 283 271 264 299 273 293 329 353 378 401 417 412 415 446 487 4967-year 162 167 175 204 237 236 226 246 236 255 294 318 333 358 370 366 373 417 4378-year 135 134 149 174 204 213 199 225 203 229 259 287 301 321 338 329 341 3849-year 115 112 119 154 182 194 172 198 185 207 233 258 273 302 313 308 30810-year 98 96 104 137 171 171 156 181 166 196 213 231 243 272 286 28611-year 87 86 92 127 156 155 144 170 144 186 201 201 221 251 25612-year 78 76 84 112 143 148 131 153 139 171 190 190 208 23213-year 67 66 76 103 136 132 119 144 130 161 170 181 19014-year 61 60 70 96 124 126 113 141 117 151 162 16915-year 53 57 62 93 120 115 110 124 114 143 15016-year 49 51 57 87 108 98 106 114 105 13517-year 46 47 54 82 101 89 99 107 10318-year 40 43 51 76 99 84 87 9919-year 38 38 49 70 90 78 8120-year 33 35 47 68 77 71
Table 189Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 678 696 732 726 743 710 741 763 758 737 744 743 770 769 764 739 777 769 839 832 803 804 821 848 8242-year 523 547 593 585 598 581 611 637 615 618 618 616 654 683 645 671 683 680 742 739 727 713 730 7683-year 390 428 462 467 493 448 504 536 509 526 512 527 564 606 570 586 603 595 669 666 646 638 6684-year 308 336 366 371 413 396 409 438 429 434 463 469 479 519 509 522 523 529 615 593 574 5875-year 243 258 283 304 363 335 316 382 348 360 402 418 424 465 474 479 481 477 535 537 5196-year 192 208 235 253 318 295 265 341 300 302 353 366 379 408 419 435 431 413 484 5037-year 154 169 192 214 261 255 225 282 261 263 316 332 346 366 365 381 390 393 4408-year 130 138 162 187 222 237 202 258 217 236 277 299 310 334 344 344 365 3589-year 110 117 130 168 202 209 183 236 195 200 249 269 287 315 318 321 33310-year 92 99 112 149 192 180 165 220 176 188 223 243 241 290 285 29411-year 75 89 99 138 176 167 150 211 145 174 211 217 218 270 25012-year 69 77 94 122 157 163 145 191 138 158 199 210 207 25813-year 58 67 86 114 151 142 132 176 131 149 179 201 19114-year 52 61 80 106 135 138 128 172 115 142 175 18815-year 46 57 71 102 133 124 123 161 111 138 15916-year 44 52 68 98 116 95 118 147 102 13817-year 39 48 64 91 108 91 109 143 10118-year 35 44 62 84 105 91 91 13419-year 33 42 61 75 95 87 9020-year 27 39 60 73 82 74
Table 1810Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Survival Time
1-year 682 693 713 711 736 700 746 735 713 710 709 726 777 723 761 746 766 789 798 790 795 831 808 808 8122-year 520 543 559 562 575 569 601 610 581 578 576 644 647 644 655 656 648 702 712 699 708 764 715 7283-year 404 429 443 456 460 450 469 486 449 470 478 545 553 564 583 580 551 643 636 642 654 701 6574-year 322 348 347 367 387 365 365 357 347 389 418 469 480 496 508 503 485 592 577 584 586 6195-year 261 280 265 293 299 299 311 300 277 329 347 378 419 442 458 446 441 531 522 525 5016-year 210 212 207 237 245 246 263 253 242 283 301 338 377 392 416 387 392 482 489 4867-year 171 164 158 194 210 217 226 206 207 245 268 300 320 349 375 349 350 442 4338-year 141 130 136 159 182 187 195 187 186 219 239 270 292 306 332 312 307 4119-year 120 107 109 139 161 178 162 156 172 214 215 243 257 286 306 294 27410-year 105 94 96 124 148 161 147 140 155 204 202 216 246 252 287 27711-year 100 84 84 115 134 143 137 125 142 200 188 181 223 229 26312-year 87 75 73 101 125 132 115 111 140 185 180 164 208 20113-year 75 65 67 92 117 121 104 109 127 175 161 155 18814-year 69 60 60 85 111 112 96 107 118 161 147 14515-year 60 56 52 82 105 104 96 83 115 146 14016-year 54 50 47 74 99 100 92 77 108 13117-year 52 45 44 71 91 85 88 68 10318-year 45 41 40 67 91 74 83 6119-year 43 34 38 64 84 67 7120-year 39 31 35 62 71 67
Table 1811Myeloma
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 082 042 Asian 0 000 000 000 055 028
10 000 000 001 082 043 Pacific 10 000 000 000 055 028
20 000 001 004 083 043 Islander 20 000 000 002 055 028
30 001 004 013 083 043 30 000 002 007 055 028
40 003 013 031 084 044 40 002 006 019 055 028
50 009 029 057 082 044 50 005 017 036 054 028
60 020 050 072 077 045 60 013 032 047 051 028
70 033 058 - 064 042 70 021 036 - 041 025
80 033 - - 040 033 80 018 - - 023 019
White 0 000 000 000 075 040 American 0 000 000 000 057 036
10 000 000 001 075 040 Indian 10 000 000 001 058 037
20 000 001 003 076 040 Alaska 20 000 001 004 058 037
30 001 003 011 076 041 Nativea 30 001 004 011 059 037
40 003 011 028 077 041 40 003 010 020 059 039
50 008 026 051 076 042 50 007 017 040 058 040
60 018 045 067 071 042 60 011 036 052 055 041
70 030 054 - 059 040 70 028 047 - 050 040
80 032 - - 038 031 80 025 - - 029 032
Black 0 000 000 000 139 069 Hispanicb 0 000 000 000 086 042
10 000 000 002 141 070 10 000 000 001 086 043
20 000 002 009 142 071 20 000 001 004 087 043
30 001 009 026 144 071 30 001 004 013 087 043
40 007 025 061 145 073 40 003 012 031 087 043
50 018 055 104 142 074 50 009 028 057 086 043
60 040 093 127 135 075 60 020 050 075 080 043
70 063 103 - 112 072 70 033 061 - 065 040
80 057 - - 070 058 80 034 - - 040 030
Table 1812
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 093 047 Asian 0 000 000 000 067 031
10 000 000 001 094 048 Pacific 10 000 000 000 067 032
20 000 001 004 095 048 Islander 20 000 000 002 067 032
30 001 004 015 096 049 30 000 002 008 068 032
40 004 014 037 097 050 40 002 007 023 068 032
50 011 034 067 096 050 50 006 021 045 067 032
60 025 060 086 091 051 60 016 040 058 063 031
70 041 071 - 077 049 70 026 046 - 051 028
80 042 - - 051 040 80 024 - - 031 022
White 0 000 000 000 087 045 American 0 000 000 000 059 035
10 000 000 001 088 046 Indian 10 000 000 002 060 036
20 000 001 004 089 046 Alaska 20 000 002 005 060 036
30 001 004 013 090 047 Nativea 30 002 005 013 062 037
40 003 013 033 091 047 40 003 011 021 062 038
50 010 031 062 090 048 50 008 018 040 061 040
60 023 056 081 086 049 60 011 034 052 058 041
70 038 068 - 073 047 70 027 048 - 055 043
80 041 - - 049 039 80 029 - - 038 037
Black 0 000 000 000 146 070 Hispanicb 0 000 000 000 096 047
10 000 000 002 149 072 10 000 000 001 096 048
20 000 002 009 150 072 20 000 001 004 097 048
30 002 009 028 152 074 30 001 004 014 098 049
40 008 027 069 155 075 40 003 013 034 098 049
50 020 064 115 154 077 50 010 032 065 097 050
60 048 105 140 148 079 60 023 058 087 092 050
70 071 115 - 125 078 70 040 073 - 078 047
80 068 - - 082 066 80 043 - - 050 037
Table 1813
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 000 000 071 038 Asian 0 000 000 000 045 025
10 000 000 001 071 038 Pacific 10 000 000 000 045 025
20 000 001 004 072 038 Islander 20 000 000 002 045 025
30 001 004 011 072 039 30 000 002 006 045 025
40 003 011 026 072 039 40 001 006 015 045 026
50 008 024 047 070 039 50 004 014 029 044 025
60 017 041 060 065 039 60 010 025 037 040 025
70 027 048 - 053 036 70 016 029 - 032 022
80 027 - - 033 028 80 014 - - 018 017
White 0 000 000 000 063 035 American 0 000 000 000 056 038
10 000 000 001 064 035 Indian 10 000 000 001 056 039
20 000 001 003 064 035 Alaska 20 000 001 004 057 039
30 001 003 010 064 035 Nativea 30 001 004 009 057 039
40 003 009 023 064 036 40 003 009 018 057 040
50 007 021 041 062 036 50 006 016 041 056 041
60 015 036 054 058 036 60 010 037 052 053 041
70 024 043 - 048 034 70 029 046 - 047 039
80 025 - - 031 026 80 022 - - 023 029
Black 0 000 000 000 133 068 Hispanicb 0 000 000 000 078 038
10 000 000 001 136 070 10 000 000 001 078 038
20 000 001 008 136 070 20 000 001 004 078 038
30 001 008 024 137 070 30 001 003 011 078 038
40 007 023 054 137 071 40 003 011 028 078 038
50 017 048 095 134 072 50 008 025 051 076 038
60 034 083 117 125 072 60 018 044 066 070 038
70 056 095 - 104 068 70 028 052 - 056 034
80 051 - - 063 054 80 028 - - 034 025
Table 1814
Myeloma
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb
Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d
Rate per 100000 persons AAPC () AAPC ()
Total Males Females Total Males Females Total Males Females RaceEthnicity
All Races 69 87 56 11 08 12 15 09 08
White 63 81 49 10 07 09 08 09 06White Hispanice 66 82 55 02 00 02 - - -White Non-Hispanice 62 81 48 06 05 05 - - -
Black 137 163 119 04 02 12 02 08 09
AsianPacific Islander 38 49 30 06 15 -03 - - -
Amer IndAlaska Natf 54 60 50 -02 13 -14 - - -
Hispanice 67 82 55 04 05 04 - - -
US Mortalityg Rate 2012-2016 Trend 2007-2016h
Rate per 100000 persons AAPC ()
Total Males Females Total Males FemalesRaceEthnicity
All Races 33 42 27 -06 -09 -08
White 31 40 24 -06 -08 -07White Hispanice 29 36 24 -08 -06 -12White Non-Hispanice 31 40 24 -06 -08 -07
Black 62 74 54 -05 -11 -07
AsianPacific Islander 16 20 12 -05 03 -14
Amer IndAlaska NatTotal US 21 24 19 -29 -27 -32PRCDA Counties 31 34 28 -18 -19 -16Non-PRCDA Counties 11 14 09 -46 -40 -65
Hispanice 28 34 23 -10 -07 -14
Table 1815Myeloma
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidence Ratesa 2012-2016
California 590 754 457 586 752 450 1207 1510 972Greater Bay Area 589 772 441 593 789 432 1246 1597 973San Francisco-Oakland 597 787 445 584 788 418 1239 1554 997San Jose-Monterey 573 743 433 609 789 458 1233 1802 -
Los Angeles 586 756 451 577 751 439 1202 1515 971Greater California 592 747 465 587 742 459 1189 1469 963
Connecticut 721 910 573 650 831 509 1413 1707 1173Detroit 840 1046 682 683 883 524 1438 1732 1240Georgia 857 1032 726 632 816 485 1562 1829 1400Atlanta 937 1134 793 674 885 509 1477 1759 1301Rural Georgia 840 938 786 587 705 - 1457 1571 1416Greater Georgia 822 993 692 620 798 477 1627 1880 1473
Hawaii 542 650 446 658 805 504 - - -Idaho 636 794 486 632 791 480 - - -Iowa 687 883 529 673 873 512 1566 1393 1758Kentucky 695 938 508 647 884 463 1388 1752 1130Louisiana 814 1002 674 631 814 492 1350 1616 1163Massachusetts 579 732 459 540 696 417 1205 1268 1146New Jersey 720 888 599 645 832 505 1239 1375 1156New Mexico 553 696 434 526 671 403 1021 - -New York 813 1009 667 722 912 576 1393 1706 1196Seattle-Puget Sound 673 856 524 658 844 502 1225 1451 1054Utah 620 789 477 608 767 475 1610 - -
SEER 9 Areasb 697 875 554 637 822 486 1406 1672 1217SEER 13 Areasb 665 841 525 623 806 475 1360 1639 1160SEER 18 Areasb 675 848 539 619 798 475 1365 1619 1188SEER 21 Areasb 693 868 556 631 810 488 1366 1629 1187
Table 1816Myeloma
Age-Adjusted SEER Incidence Ratesa
By Registry Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Death Ratesa 2012-2016
California 304 391 236 313 410 237 640 741 568Greater Bay Area 285 364 226 310 408 236 664 760 595San Francisco-Oakland 293 370 234 307 406 231 687 796 609San Jose-Monterey 271 354 209 315 413 245 465 - -
Los Angeles 308 398 241 304 408 227 674 779 605Greater California 309 398 238 317 412 241 590 692 511
Connecticut 307 366 264 291 357 242 559 579 540Detroit 384 500 301 323 455 225 626 712 569Georgia 379 470 316 299 387 234 658 820 573Atlanta 409 539 320 312 424 224 630 918 485Rural Georgia 332 - - - - - 661 - -Greater Georgia 369 447 315 298 381 238 678 764 631
Hawaii 258 341 191 320 428 222 - - -Idaho 351 438 278 355 445 278 - - -Iowa 349 450 277 347 451 272 629 - -Kentucky 337 463 242 324 452 227 599 751 497Louisiana 378 467 312 302 381 246 625 767 523Massachusetts 313 395 253 305 388 245 562 617 525New Jersey 316 403 256 301 397 234 557 605 523New Mexico 287 338 246 285 347 235 - - -New York 305 376 255 287 358 235 478 595 406Seattle-Puget Sound 315 390 255 316 399 247 611 589 656Utah 351 424 288 343 410 285 - - -
SEER 9 Areasb 329 413 266 315 407 245 626 746 551SEER 13 Areasb 321 406 257 313 407 241 635 748 563SEER 18 Areasb 325 413 259 312 407 239 624 727 556SEER 21 Areasb 321 405 258 308 398 240 582 689 513
Total US 331 417 266 308 396 240 621 743 543
Table 1817Myeloma
Age-Adjusted SEER Death Ratesa
By Registry Race and Sex
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 331 001
High Five StatesSouth Carolina 430 013 01(0104) 2998c
Mississippi 399 016 02(0118) 2036c
Maryland 397 011 03(0114) 1989c
North Carolina 382 008 04(0216) 1545c
Georgia 379 009 05(0218) 1434
Low Five StatesNew Mexico 287 016 47(2651) -1342Nevada 286 014 48(2951) -1358Arizona 286 009 49(3651) -1374Rhode Island 271 021 50(2451) -1817c
Hawaii 258 018 51(3751) -2205c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 366 011 10(0228) 1056 Montana 322 023 33(0451) -276Alaska 306 035 40(0251) -751 Nebraska 331 018 29(0549) 000Arizona 286 009 49(3651) -1374 Nevada 286 014 48(2951) -1358Arkansas 329 014 31(0947) -067 New Hampshire 295 019 46(1451) -1082California 304 004 43(3447) -820 New Jersey 316 008 36(2146) -444Colorado 314 011 37(2049) -531 New Mexico 287 016 47(2651) -1342Connecticut 307 012 39(2150) -731 New York 305 005 41(3148) -790Delaware 375 025 08(0143) 1324 North Carolina 382 008 04(0216) 1545c
DC 366 035 11(0150) 1040 North Dakota 361 030 13(0148) 894Florida 297 005 45(3749) -1029 Ohio 358 007 14(0526) 810Georgia 379 009 05(0218) 1434 Oklahoma 331 012 28(1046) 002Hawaii 258 018 51(3751) -2205c Oregon 348 012 19(0438) 518Idaho 351 020 17(0246) 601 Pennsylvania 331 006 30(1739) -008Illinois 329 007 32(1640) -079 Rhode Island 271 021 50(2451) -1817c
Indiana 345 010 22(0837) 405 South Carolina 430 013 01(0104) 2998c
Iowa 349 014 18(0440) 548 South Dakota 353 027 15(0149) 660Kansas 368 015 09(0233) 1103 Tennessee 377 010 07(0220) 1377Kentucky 337 012 26(0842) 190 Texas 317 005 35(2544) -419Louisiana 378 013 06(0223) 1405 Utah 351 018 16(0244) 605Maine 304 018 42(1451) -811 Vermont 336 029 27(0151) 143Maryland 397 011 03(0114) 1989c Virginia 343 009 23(1037) 361Massachusetts 313 009 38(2148) -558 Washington 322 009 34(1746) -280Michigan 362 008 12(0426) 939 West Virginia 346 017 20(0346) 444Minnesota 341 011 24(0940) 302 Wisconsin 338 010 25(1140) 195Mississippi 399 016 02(0118) 2036c Wyoming 299 031 44(0351) -978Missouri 345 010 21(0837) 415
Table 1818Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 417 002
High Five StatesSouth Carolina 524 022 01(0116) 2557c
Mississippi 501 027 02(0131) 1999c
Tennessee 488 018 03(0124) 1705c
Maryland 481 019 04(0129) 1527c
Alabama 481 021 05(0130) 1523c
Low Five StatesArizona 361 014 47(3351) -1354Maine 356 030 48(1651) -1459Hawaii 341 030 49(2251) -1825c
New Mexico 338 026 50(2951) -1894c
Rhode Island 318 035 51(2651) -2383c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 481 021 05(0130) 1523c Montana 417 038 33(0251) -009Alaska 381 060 41(0151) -860 Nebraska 472 032 07(0141) 1320Arizona 361 014 47(3351) -1354 Nevada 367 024 45(2251) -1214Arkansas 417 024 32(0648) 002 New Hampshire 372 033 43(0951) -1084California 391 007 40(3045) -617 New Jersey 403 014 35(1846) -340Colorado 401 019 37(1448) -392 New Mexico 338 026 50(2951) -1894c
Connecticut 366 020 46(2651) -1216 New York 376 009 42(3349) -998Delaware 461 042 15(0149) 1043 North Carolina 456 014 16(0332) 940DC 434 060 26(0151) 407 North Dakota 478 052 06(0149) 1463Florida 371 008 44(3649) -1115 Ohio 448 012 20(0533) 729Georgia 470 016 09(0229) 1254 Oklahoma 422 022 29(0646) 104Hawaii 341 030 49(2251) -1825c Oregon 442 021 22(0341) 603Idaho 438 034 23(0148) 509 Pennsylvania 419 011 31(1541) 043Illinois 414 012 34(1742) -080 Rhode Island 318 035 51(2651) -2383c
Indiana 452 017 18(0335) 843 South Carolina 524 022 01(0116) 2557c
Iowa 450 024 19(0242) 785 South Dakota 470 046 08(0149) 1267Kansas 468 026 10(0138) 1228 Tennessee 488 018 03(0124) 1705c
Kentucky 463 021 13(0136) 1103 Texas 396 009 38(2645) -502Louisiana 467 022 11(0135) 1203 Utah 424 029 28(0349) 164Maine 356 030 48(1651) -1459 Vermont 465 052 12(0150) 1137Maryland 481 019 04(0129) 1527c Virginia 436 015 24(0739) 460Massachusetts 395 016 39(2048) -531 Washington 401 016 36(1747) -377Michigan 461 014 14(0329) 1060 West Virginia 435 029 25(0248) 437Minnesota 433 018 27(0642) 380 Wisconsin 421 017 30(1045) 082Mississippi 501 027 02(0131) 1999c Wyoming 445 058 21(0151) 674Missouri 456 017 17(0234) 923
Table 1819Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 266 002
High Five StatesSouth Carolina 368 015 01(0106) 3799c
Maryland 340 014 02(0111) 2749c
North Carolina 330 010 03(0111) 2382c
Mississippi 324 019 04(0124) 2157c
DC 316 043 05(0150) 1866c
Low Five StatesArizona 222 010 47(3351) -1651c
Nebraska 221 019 48(1651) -1720c
Nevada 213 017 49(2351) -2022c
Wyoming 192 034 50(0951) -2795c
Hawaii 191 020 51(2951) -2848c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Alabama 284 013 14(0438) 657 Montana 236 027 44(0451) -1152Alaska 244 042 39(0151) -856 Nebraska 221 019 48(1651) -1720c
Arizona 222 010 47(3351) -1651c Nevada 213 017 49(2351) -2022c
Arkansas 263 016 27(0748) -137 New Hampshire 238 023 41(0751) -1080California 236 005 43(3448) -1127 New Jersey 256 009 33(1546) -386Colorado 248 013 37(1249) -686 New Mexico 246 020 38(0751) -761Connecticut 264 014 26(0747) -103 New York 255 006 35(1943) -443Delaware 305 031 08(0147) 1455 North Carolina 330 010 03(0111) 2382c
DC 316 043 05(0150) 1866c North Dakota 274 035 20(0151) 265Florida 238 006 42(3048) -1085 Ohio 293 009 11(0526) 977Georgia 316 011 06(0217) 1856c Oklahoma 262 015 29(0747) -156Hawaii 191 020 51(2951) -2848c Oregon 275 015 19(0544) 312Idaho 278 025 16(0249) 417 Pennsylvania 268 008 23(1139) 047Illinois 269 008 22(1039) 097 Rhode Island 235 026 45(0651) -1181Indiana 266 011 25(0944) -028 South Carolina 368 015 01(0106) 3799c
Iowa 277 016 17(0444) 399 South Dakota 258 030 32(0251) -324Kansas 295 018 10(0240) 1069 Tennessee 299 012 09(0328) 1212Kentucky 242 013 40(1650) -919 Texas 256 006 34(1843) -407Louisiana 312 015 07(0125) 1719c Utah 288 022 13(0246) 822Maine 262 022 30(0450) -175 Vermont 233 033 46(0351) -1272Maryland 340 014 02(0111) 2749c Virginia 273 011 21(0840) 234Massachusetts 253 010 36(1447) -512 Washington 259 011 31(1146) -299Michigan 289 009 12(0530) 843 West Virginia 278 020 15(0347) 438Minnesota 268 013 24(0845) 041 Wisconsin 275 012 18(0641) 316Mississippi 324 019 04(0124) 2157c Wyoming 192 034 50(0951) -2795c
Missouri 262 011 28(1045) -156
Table 1820Myeloma
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex
All Races Both Sexes 78454 32030 12390 4580 1515 128969 2423 131392Males 44371 17567 6651 2646 818 72052 947 72999Females 34083 14463 5740 1934 697 56917 1475 58392
White Both Sexes 58668 24166 9726 3553 1216 97330 + +Males 34273 13673 5361 2174 660 56140 + +Females 24395 10494 4366 1380 556 41190 + +
Black Both Sexes 16092 6595 2225 772 216 25900 + +Males 8066 3203 1002 354 127 12751 + +Females 8027 3392 1223 418 90 13149 + +
Asian Both Sexes 2202 821 243 129 55 3450 + +Pacific Males 1205 447 141 52 17 1861 + +Islander Females 998 375 102 77 38 1589 + +
Hispanic Both Sexes 6254 2272 955 421 106 10008 + +Males 3491 1278 517 242 76 5603 + +Females 2763 995 439 178 30 4404 + +
Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages
Race Sex
All Races Both Sexes 00400 - 00000 00003 00026 00146 00464 01106 01970 01862 00337Males 00454 - 00000 00004 00032 00167 00540 01311 02459 02554 00416Females 00348 - 00000 00003 00020 00126 00391 00921 01563 01437 00274
White Both Sexes 00386 - 00000 00004 00022 00126 00408 00989 01785 01734 00304Males 00449 - 00001 00004 00028 00144 00488 01203 02258 02447 00383Females 00324 - - 00003 00017 00108 00330 00790 01383 01288 00239
Black Both Sexes 00574 - 00001 00001 00049 00307 00885 02156 03846 03403 00652Males 00589 - - - 00059 00360 00959 02386 04730 04272 00766Females 00560 - 00003 00002 00040 00260 00821 01971 03231 02973 00572
Asian Both Sexes 00169 - - 00003 00017 00067 00221 00594 01125 01085 00184Pacific Males 00191 - - 00004 00027 00082 00259 00706 01417 01314 00226Islander Females 00150 - - - 00008 00054 00188 00503 00891 00937 00151
Hispanic Both Sexes 00175 00000 00001 00005 00026 00125 00377 00870 01684 01325 00275Males 00194 - 00001 00006 00030 00143 00466 01013 02056 01864 00338Females 00156 00001 - 00003 00022 00106 00289 00744 01399 00992 00225
Table 1821Myeloma (Invasive)
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
0
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 20160
5
10
15
20
1975 1985 1995 2005 2016
Delay-Adj IncidenceDelay-Adj Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMyeloma by Race and Sex
a
Figure 181
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
a
White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000
Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 09
US Mortality APC1994-16 = -08
SEER Incidence APCsDelay Adj 1975-16 = 10Observed 1975-16 = 08
US Mortality APC1991-16 = -12
SEER Incidence APCsDelay Adj 1975-16 = 07Observed 1975-16 = 06
US Mortality APC2008-16 = -04
SEER Incidence APCsDelay Adj 1975-16 = 11Observed 1975-16 = 09
US Mortality APC2013-16 = -37
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
3
6
9
12
15
1975 1985 1995 2005 20160
3
6
9
12
15
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMyeloma Both Sexes
Figure 182
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Year of Diagnosis Year of Death
a
d
a
b
c
c
b
d
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Figure 183
Myeloma5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
