38
SEER Cancer Statistics Review 1975-2014 National Cancer Institute Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/). The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta). b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry). c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention. d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint. e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma. g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties. * The APC/AAPC is significantly different from zero (p<.05). - Joinpoint regression line analysis could not be performed on data series. JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPC d Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14 SEER 9 Delay-Adjusted Incidence a , 1975-2014 All Races 1975-80 -0.5 1980-87 4.0* 1987-94 -0.2 1994-99 1.8* 1999-04 -2.3* 2004-14 0.4* 0.4* 0.4* White 1975-80 -0.5 1980-87 4.1* 1987-94 -0.2 1994-99 2.0* 1999-04 -2.4* 2004-14 0.2 0.2 0.2 Black 1975-91 2.2* 1991-14 0.3* 0.3* 0.3* SEER 13 Delay-Adjusted Incidence b , 1992-2014 All Races 1992-99 1.3* 1999-04 -2.2* 2004-14 0.3 0.3 0.3 White 1992-99 1.5* 1999-04 -2.4* 2004-14 0.1 0.1 0.1 Black 1992-14 0.3* 0.3* 0.3* SEER 9 Observed Incidence a , 1975-2014 All Races 1975-80 -0.5 1980-87 4.0* 1987-94 -0.2 1994-99 1.8* 1999-04 -2.3* 2004-14 0.3 0.3 0.3 White 1975-80 -0.5 1980-87 4.1* 1987-94 -0.2 1994-99 2.0* 1999-04 -2.4* 2004-14 0.1 0.1 0.1 Black 1975-91 2.3* 1991-14 0.3* 0.3* 0.3* SEER 13 Observed Incidence b , 1992-2014 All Races 1992-99 1.3* 1999-04 -2.2* 2004-14 0.2 0.2 0.2 White 1992-99 1.5* 1999-04 -2.3* 2004-14 0.0 0.0 0.0 White NH ef 1992-99 1.7* 1999-04 -2.3* 2004-14 0.1 0.1 0.1 Black 1992-14 0.2* 0.2* 0.2* Black NH ef 1992-14 0.3* 0.3* 0.3* API e 1992-94 -4.6 1994-97 6.9 1997-05 -0.7 2005-14 1.2* 1.2* 1.2* AI/AN eg 1992-14 0.1 0.1 0.1 Hispanic f 1992-14 0.2 0.2 0.2 U.S. Cancer Mortality c , 1975-2014 All Races 1975-90 0.4* 1990-95 -1.8* 1995-98 -3.3* 1998-14 -1.8* -1.8* -1.8* White 1975-90 0.3* 1990-95 -2.0* 1995-98 -3.6* 1998-14 -1.9* -1.9* -1.9* Black 1975-93 1.4* 1993-14 -1.5* -1.5* -1.5* U.S. Cancer Mortality c , 1992-2014 All Races 1992-95 -1.2* 1995-98 -3.6* 1998-03 -1.6* 2003-07 -2.3* 2007-14 -1.6* -1.8* -1.6* White 1992-95 -1.5* 1995-98 -3.7* 1998-14 -1.9* -1.9* -1.9* White NH ef 1992-95 -1.2* 1995-98 -3.7* 1998-14 -1.8* -1.8* -1.8* Black 1992-95 0.4 1995-14 -1.5* -1.5* -1.5* Black NH ef 1992-95 0.5 1995-14 -1.5* -1.5* -1.5* API e 1992-14 -0.9* -0.9* -0.9* AI/AN eg 1992-05 0.6 2005-14 -3.1* -3.1* -3.1* Hispanic f 1992-96 1.4 1996-99 -4.0 1999-11 -1.5* 2011-14 1.1 -0.6 0.5 Table 4.1 Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints, All Ages by Race/Ethnicity

SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

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Page 1: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.* The APC/AAPC is significantly different from zero (p<.05).- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14

SEER 9 Delay-Adjusted Incidencea, 1975-2014All Races 1975-80 -0.5 1980-87 4.0* 1987-94 -0.2 1994-99 1.8* 1999-04 -2.3* 2004-14 0.4* 0.4* 0.4*White 1975-80 -0.5 1980-87 4.1* 1987-94 -0.2 1994-99 2.0* 1999-04 -2.4* 2004-14 0.2 0.2 0.2Black 1975-91 2.2* 1991-14 0.3* 0.3* 0.3*

SEER 13 Delay-Adjusted Incidenceb, 1992-2014All Races 1992-99 1.3* 1999-04 -2.2* 2004-14 0.3 0.3 0.3White 1992-99 1.5* 1999-04 -2.4* 2004-14 0.1 0.1 0.1Black 1992-14 0.3* 0.3* 0.3*

SEER 9 Observed Incidencea, 1975-2014All Races 1975-80 -0.5 1980-87 4.0* 1987-94 -0.2 1994-99 1.8* 1999-04 -2.3* 2004-14 0.3 0.3 0.3White 1975-80 -0.5 1980-87 4.1* 1987-94 -0.2 1994-99 2.0* 1999-04 -2.4* 2004-14 0.1 0.1 0.1Black 1975-91 2.3* 1991-14 0.3* 0.3* 0.3*

SEER 13 Observed Incidenceb, 1992-2014All Races 1992-99 1.3* 1999-04 -2.2* 2004-14 0.2 0.2 0.2White 1992-99 1.5* 1999-04 -2.3* 2004-14 0.0 0.0 0.0White NHef 1992-99 1.7* 1999-04 -2.3* 2004-14 0.1 0.1 0.1

Black 1992-14 0.2* 0.2* 0.2*Black NHef 1992-14 0.3* 0.3* 0.3*

APIe 1992-94 -4.6 1994-97 6.9 1997-05 -0.7 2005-14 1.2* 1.2* 1.2*AI/ANeg 1992-14 0.1 0.1 0.1Hispanicf 1992-14 0.2 0.2 0.2

U.S. Cancer Mortalityc, 1975-2014All Races 1975-90 0.4* 1990-95 -1.8* 1995-98 -3.3* 1998-14 -1.8* -1.8* -1.8*White 1975-90 0.3* 1990-95 -2.0* 1995-98 -3.6* 1998-14 -1.9* -1.9* -1.9*Black 1975-93 1.4* 1993-14 -1.5* -1.5* -1.5*

U.S. Cancer Mortalityc, 1992-2014All Races 1992-95 -1.2* 1995-98 -3.6* 1998-03 -1.6* 2003-07 -2.3* 2007-14 -1.6* -1.8* -1.6*White 1992-95 -1.5* 1995-98 -3.7* 1998-14 -1.9* -1.9* -1.9*White NHef 1992-95 -1.2* 1995-98 -3.7* 1998-14 -1.8* -1.8* -1.8*

Black 1992-95 0.4 1995-14 -1.5* -1.5* -1.5*Black NHef 1992-95 0.5 1995-14 -1.5* -1.5* -1.5*

APIe 1992-14 -0.9* -0.9* -0.9*AI/ANeg 1992-05 0.6 2005-14 -3.1* -3.1* -3.1*Hispanicf 1992-96 1.4 1996-99 -4.0 1999-11 -1.5* 2011-14 1.1 -0.6 0.5

Table 4.1Cancer of the Female Breast (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints,

All Ages by Race/Ethnicity

Page 2: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.* The APC/AAPC is significantly different from zero (p<.05).- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14

SEER 9 Delay-Adjusted Incidencea, 1975-2014All Races 1975-80 -1.3 1980-87 2.7* 1987-94 -0.8 1994-14 0.3* 0.3* 0.3*White 1975-80 -1.1 1980-87 2.7* 1987-94 -0.8 1994-14 0.3* 0.3* 0.3*Black 1975-91 1.2* 1991-14 -0.2 -0.2 -0.2

SEER 13 Delay-Adjusted Incidenceb, 1992-2014All Races 1992-14 0.2* 0.2* 0.2*White 1992-14 0.2* 0.2* 0.2*Black 1992-02 -1.3* 2002-05 3.8 2005-14 -0.6 -0.6 -0.6

SEER 9 Observed Incidencea, 1975-2014All Races 1975-80 -1.3 1980-87 2.7* 1987-94 -0.8 1994-14 0.2* 0.2* 0.2*White 1975-80 -1.1 1980-87 2.6* 1987-94 -0.8 1994-14 0.2* 0.2* 0.2*Black 1975-91 1.3* 1991-14 -0.2 -0.2 -0.2

SEER 13 Observed Incidenceb, 1992-2014All Races 1992-14 0.2* 0.2* 0.2*White 1992-14 0.1* 0.1* 0.1*White NHef 1992-14 0.4* 0.4* 0.4*

Black 1992-02 -1.3* 2002-05 3.8 2005-14 -0.9* -0.9* -0.9*Black NHef 1992-02 -1.4* 2002-05 4.3 2005-14 -0.7 -0.7 -0.7

APIe 1992-14 0.9* 0.9* 0.9*AI/ANeg 1992-14 -0.2 -0.2 -0.2Hispanicf 1992-14 0.1 0.1 0.1

U.S. Cancer Mortalityc, 1975-2014All Races 1975-90 -0.4* 1990-07 -3.2* 2007-14 -1.3* -1.7* -1.3*White 1975-90 -0.6* 1990-04 -3.7* 2004-14 -1.7* -1.7* -1.7*Black 1975-87 1.8* 1987-95 -1.2* 1995-14 -2.4* -2.4* -2.4*

U.S. Cancer Mortalityc, 1992-2014All Races 1992-07 -3.1* 2007-14 -1.4* -1.8* -1.4*White 1992-04 -3.7* 2004-14 -1.7* -1.7* -1.7*White NHef 1992-00 -4.1* 2000-14 -2.2* -2.2* -2.2*

Black 1992-14 -2.3* -2.3* -2.3*Black NHef 1992-96 -0.4 1996-99 -4.3 1999-05 -1.2 2005-08 -4.1 2008-14 -1.5* -2.4* -1.5*

APIe 1992-01 -0.8 2001-08 -5.2* 2008-14 1.4 -0.9 1.4AI/ANeg 1992-14 -2.2* -2.2* -2.2*Hispanicf 1992-10 -2.9* 2010-14 2.1 -0.7 2.1

Table 4.2Cancer of the Female Breast (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints,

Ages <50 by Race/Ethnicity

Page 3: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.* The APC/AAPC is significantly different from zero (p<.05).- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14

SEER 9 Delay-Adjusted Incidencea, 1975-2014All Races 1975-82 0.9 1982-87 5.3* 1987-93 -0.3 1993-99 1.9* 1999-05 -2.6* 2005-14 0.6* 0.6* 0.6*White 1975-82 0.9* 1982-87 5.5* 1987-93 -0.3 1993-00 1.7* 2000-04 -3.9* 2004-14 0.3 0.3 0.3Black 1975-88 3.2* 1988-14 0.6* 0.6* 0.6*

SEER 13 Delay-Adjusted Incidenceb, 1992-2014All Races 1992-99 1.7* 1999-04 -2.9* 2004-14 0.2 0.2 0.2White 1992-00 1.4* 2000-04 -3.7* 2004-14 0.1 0.1 0.1Black 1992-14 0.5* 0.5* 0.5*

SEER 9 Observed Incidencea, 1975-2014All Races 1975-82 0.9 1982-87 5.3* 1987-93 -0.3 1993-99 1.9* 1999-05 -2.5* 2005-14 0.5* 0.5* 0.5*White 1975-82 0.9* 1982-87 5.5* 1987-93 -0.3 1993-00 1.7* 2000-04 -3.8* 2004-14 0.2 0.2 0.2Black 1975-92 2.6* 1992-14 0.4* 0.4* 0.4*

SEER 13 Observed Incidenceb, 1992-2014All Races 1992-99 1.7* 1999-04 -2.8* 2004-14 0.1 0.1 0.1White 1992-99 1.8* 1999-04 -2.9* 2004-14 -0.1 -0.1 -0.1White NHef 1992-01 1.3* 2001-04 -5.0* 2004-14 0.2 0.2 0.2

Black 1992-14 0.4* 0.4* 0.4*Black NHef 1992-14 0.4* 0.4* 0.4*

APIe 1992-99 3.0* 1999-03 -2.5 2003-14 1.1* 1.1* 1.1*AI/ANeg 1992-14 0.2 0.2 0.2Hispanicf 1992-14 0.2 0.2 0.2

U.S. Cancer Mortalityc, 1975-2014All Races 1975-90 0.5* 1990-95 -1.6* 1995-98 -3.0* 1998-14 -1.8* -1.8* -1.8*White 1975-89 0.5* 1989-95 -1.4* 1995-98 -3.3* 1998-14 -1.8* -1.8* -1.8*Black 1975-93 1.6* 1993-14 -1.3* -1.3* -1.3*

U.S. Cancer Mortalityc, 1992-2014All Races 1992-95 -1.2* 1995-98 -3.1* 1998-14 -1.8* -1.8* -1.8*White 1992-94 -0.6 1994-97 -3.4* 1997-14 -1.8* -1.8* -1.8*White NHef 1992-94 -0.1 1994-97 -3.3* 1997-14 -1.8* -1.8* -1.8*

Black 1992-95 0.8 1995-14 -1.3* -1.3* -1.3*Black NHef 1992-94 2.4 1994-14 -1.2* -1.2* -1.2*

APIe 1992-14 -0.6* -0.6* -0.6*AI/ANeg 1992-05 1.2 2005-14 -3.3* -3.3* -3.3*Hispanicf 1992-96 1.7 1996-00 -3.4 2000-14 -0.9* -0.9* -0.9*

Table 4.3Cancer of the Female Breast (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints,

Ages 50+ by Race/Ethnicity

Page 4: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.* The APC/AAPC is significantly different from zero (p<.05).- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14

SEER 9 Observed Incidencea, 1975-2014All Races 1975-81 -3.0 1981-87 24.9* 1987-95 4.2* 1995-98 11.8 1998-14 0.5* 0.5* 0.5*White 1975-81 -2.9 1981-87 25.4* 1987-95 3.9* 1995-98 11.1 1998-09 0.9* 2009-14 -1.6 -0.5 -1.6Black 1975-83 6.1 1983-87 23.8* 1987-98 8.2* 1998-14 1.5* 1.5* 1.5*

SEER 13 Observed Incidenceb, 1992-2014All Races 1992-99 7.3* 1999-14 0.4 0.4 0.4White 1992-94 -0.3 1994-98 10.2* 1998-09 0.7* 2009-14 -1.5 -0.5 -1.5White NHef 1992-94 0.7 1994-99 9.2* 1999-05 -0.8 2005-08 3.6 2008-14 -1.9* -0.1 -1.9*

Black 1992-98 9.1* 1998-14 1.6* 1.6* 1.6*Black NHef 1992-98 9.0* 1998-14 1.7* 1.7* 1.7*

APIe 1992-01 7.6* 2001-14 1.3* 1.3* 1.3*AI/ANeg 1992-14 1.7* 1.7* 1.7*Hispanicf 1992-98 8.5* 1998-14 1.6* 1.6* 1.6*

Table 4.4Cancer of the Female Breast (In Situ)

Trends in SEER Incidenceab Using the Joinpoint Regression Program,1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints,

All Ages by Race/Ethnicity

Page 5: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis:1975-2014 69.02 1.11 126.21 70.58 1.10 129.82 67.87 1.70 118.141975 58.06 0.85 105.08 59.47 0.88 107.39 52.10 - 93.571976 56.47 1.11 101.94 58.12 1.13 104.78 48.24 - 85.721977 55.97 0.96 100.80 57.42 0.89 103.34 49.71 - 87.141978 55.84 0.90 100.62 57.53 0.89 103.59 48.37 - 86.291979 56.83 0.99 102.09 58.28 0.94 104.70 49.91 - 86.941980 56.91 0.90 102.24 58.53 0.93 105.10 50.59 - 89.481981 59.33 1.00 106.36 61.24 0.93 109.91 54.41 - 94.351982 59.24 0.98 106.49 61.06 0.94 109.92 53.93 - 93.581983 61.89 1.04 111.12 63.67 1.13 114.40 59.08 - 103.821984 64.48 0.93 115.99 66.57 0.94 119.89 58.39 - 102.411985 69.12 0.95 124.26 70.98 0.97 127.80 64.03 - 111.541986 70.44 0.95 126.79 72.26 0.96 130.33 66.37 - 115.221987 74.79 0.96 134.50 77.80 0.98 140.24 63.13 - 109.551988 73.10 1.24 131.34 75.59 1.16 136.25 69.19 2.76 119.011989 70.76 1.13 127.25 73.39 1.07 132.40 60.73 - 105.201990 73.20 1.13 131.90 75.36 1.15 136.27 68.68 - 118.861991 74.10 1.12 133.86 76.63 1.17 138.89 67.59 - 117.721992 73.05 1.04 132.09 74.73 1.02 135.72 71.64 - 124.111993 71.33 1.08 129.20 73.14 1.04 133.10 68.86 - 119.531994 72.10 1.13 131.00 74.27 1.08 135.67 70.74 - 122.711995 72.88 0.96 132.70 75.14 0.92 137.63 71.68 - 123.851996 73.38 1.31 133.76 75.37 1.32 138.19 71.71 - 124.391997 75.62 1.10 138.06 77.57 1.07 142.59 73.10 - 126.411998 77.37 1.08 141.47 79.62 1.14 146.53 72.10 - 125.711999 77.18 0.98 141.49 79.56 0.97 147.02 72.95 - 126.292000 74.42 1.16 136.58 77.23 1.14 142.94 68.82 2.86 118.592001 75.64 1.23 138.83 78.23 1.22 144.90 66.96 1.66 116.032002 73.74 1.15 135.87 75.95 1.13 141.28 71.57 1.95 124.192003 68.99 1.33 127.10 70.86 1.34 131.83 71.42 1.85 123.952004 69.44 1.21 128.19 70.81 1.23 132.04 71.40 1.61 124.142005 68.46 1.06 126.69 70.23 1.15 131.35 68.16 - 118.812006 68.26 1.14 126.42 69.70 1.17 130.55 71.91 1.54 125.282007 69.16 1.09 128.29 70.50 1.11 132.40 71.93 1.82 124.762008 69.14 1.17 128.48 69.94 1.18 131.52 73.57 1.43 128.222009 70.44 1.17 130.93 71.43 1.23 134.40 74.25 - 129.582010 68.21 1.23 126.96 69.28 1.12 130.68 70.78 2.93 122.682011 69.97 1.34 130.38 70.77 1.28 133.68 73.85 2.67 128.402012 69.79 1.32 130.08 70.20 1.33 132.64 76.63 2.15 133.252013 69.97 1.22 130.85 70.30 1.24 133.29 73.73 1.96 128.532014 69.61 1.16 130.55 69.92 1.10 133.07 71.45 1.78 125.41

Table 4.5Cancer of the Breast (Invasive)

Age-adjusted SEER Incidencea Rates by Year, Race and Sex

Page 6: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death:1975-2014 15.66 0.31 27.66 15.49 0.30 27.48 19.63 0.54 33.361975 17.83 0.37 31.45 18.03 0.38 31.79 16.82 0.41 29.491976 18.06 0.38 31.80 18.25 0.36 32.17 17.61 0.60 30.471977 18.47 0.36 32.48 18.56 0.35 32.67 18.90 0.51 32.801978 18.05 0.36 31.73 18.12 0.35 31.90 18.63 0.60 32.141979 17.74 0.28 31.21 17.87 0.26 31.48 17.87 0.54 30.821980 18.04 0.30 31.68 18.15 0.30 31.93 18.37 0.42 31.681981 18.20 0.32 31.92 18.28 0.31 32.12 18.95 0.46 32.551982 18.39 0.33 32.19 18.42 0.32 32.31 19.68 0.56 33.751983 18.33 0.31 32.07 18.36 0.29 32.20 19.57 0.50 33.531984 18.79 0.29 32.90 18.76 0.28 32.90 20.97 0.47 35.941985 18.84 0.34 32.98 18.88 0.34 33.11 20.35 0.43 34.851986 18.76 0.28 32.87 18.76 0.27 32.93 20.69 0.42 35.441987 18.66 0.34 32.66 18.57 0.34 32.57 21.53 0.47 36.731988 18.98 0.33 33.20 18.85 0.28 33.09 22.35 0.88 37.781989 19.00 0.33 33.23 18.95 0.33 33.23 21.56 0.45 36.611990 18.93 0.28 33.14 18.79 0.26 33.02 22.49 0.52 38.001991 18.66 0.28 32.69 18.46 0.27 32.45 22.62 0.44 38.281992 18.07 0.31 31.64 17.89 0.30 31.43 21.88 0.45 37.091993 17.98 0.36 31.39 17.74 0.34 31.09 22.62 0.66 38.041994 17.67 0.35 30.92 17.40 0.34 30.56 22.44 0.60 37.741995 17.44 0.35 30.55 17.11 0.32 30.09 22.70 0.77 38.181996 16.83 0.34 29.49 16.52 0.31 29.05 22.09 0.72 37.131997 16.07 0.32 28.21 15.67 0.30 27.62 22.25 0.63 37.431998 15.67 0.32 27.54 15.32 0.31 27.01 21.08 0.56 35.531999 15.18 0.34 26.61 14.77 0.32 25.98 20.93 0.69 35.212000 15.19 0.37 26.64 14.86 0.35 26.17 20.48 0.63 34.362001 14.77 0.35 26.01 14.37 0.33 25.43 20.52 0.65 34.522002 14.54 0.31 25.62 14.13 0.29 25.02 20.32 0.61 34.142003 14.31 0.31 25.27 13.89 0.30 24.66 20.24 0.47 34.102004 13.82 0.29 24.49 13.44 0.28 23.94 19.11 0.56 32.292005 13.61 0.29 24.14 13.18 0.28 23.49 19.37 0.49 32.812006 13.25 0.29 23.56 12.87 0.29 23.02 18.73 0.47 31.622007 12.90 0.28 22.96 12.51 0.27 22.40 18.51 0.45 31.362008 12.66 0.31 22.55 12.26 0.29 21.99 18.37 0.60 30.962009 12.43 0.28 22.24 12.09 0.28 21.76 17.78 0.41 30.192010 12.26 0.30 21.92 11.85 0.28 21.33 17.77 0.59 30.162011 12.01 0.30 21.54 11.60 0.28 20.93 17.70 0.50 30.152012 11.82 0.26 21.26 11.43 0.25 20.71 17.22 0.42 29.382013 11.52 0.30 20.73 11.19 0.28 20.29 16.57 0.55 28.202014 11.40 0.29 20.55 11.04 0.27 20.04 16.45 0.54 28.06

Table 4.6Cancer of the Breast (Invasive)

Age-adjusted U.S. Deatha Rates by Year, Race and Sex

Page 7: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

Additional information on the model used to delay-adjust SEER Incidence rates can be found at(https://surveillance.cancer.gov/delay/).

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval.

All Races, Females White Females Black Females All <50 50+ All <50 50+ All <50 50+

Year of Diagnosis:1975 105.08 40.64 273.82 107.39 40.72 281.95 93.57 42.97 226.091976 101.94 40.00 264.15 104.78 40.77 272.40 85.72 38.05 210.551977 100.80 39.09 262.40 103.34 39.28 271.08 87.14 37.87 216.141978 100.62 38.87 262.30 103.59 39.32 271.90 86.29 40.20 206.951979 102.09 38.01 269.90 104.70 38.61 277.77 86.94 37.76 215.711980 102.24 37.77 271.06 105.10 38.28 280.09 89.48 37.69 225.121981 106.36 39.21 282.19 109.91 40.10 292.72 94.35 38.86 239.641982 106.49 40.55 279.14 109.92 41.20 289.85 93.58 38.02 239.061983 111.12 40.25 296.72 114.40 40.82 307.08 103.82 41.70 266.471984 115.99 42.39 308.72 119.89 43.14 320.87 102.41 44.66 253.621985 124.26 44.34 333.52 127.80 44.38 346.21 111.54 45.52 284.411986 126.79 44.46 342.40 130.33 45.24 353.15 115.22 45.64 297.401987 134.50 45.53 367.47 140.24 46.48 385.75 109.55 43.28 283.081988 131.34 44.00 360.07 136.25 44.95 375.31 119.01 43.00 318.061989 127.25 43.40 346.80 132.40 44.51 362.54 105.20 42.26 270.031990 131.90 45.64 357.77 136.27 45.39 374.24 118.86 49.05 301.661991 133.86 47.26 360.63 138.89 47.24 378.89 117.72 51.29 291.671992 132.09 43.46 364.16 135.72 43.62 376.88 124.11 46.91 326.241993 129.20 42.86 355.30 133.10 43.25 368.39 119.53 45.29 313.931994 131.00 42.44 362.90 135.67 42.80 378.86 122.71 47.65 319.261995 132.70 43.21 367.03 137.63 43.71 383.57 123.85 45.63 328.681996 133.76 43.60 369.86 138.19 44.02 384.80 124.39 44.44 333.761997 138.06 43.56 385.52 142.59 44.06 400.61 126.41 44.96 339.701998 141.47 45.53 392.72 146.53 45.50 411.10 125.71 47.10 331.571999 141.49 43.84 397.19 147.02 45.08 413.96 126.29 44.11 341.492000 136.58 43.51 380.30 142.94 43.96 402.12 118.59 44.97 311.382001 138.83 43.99 387.16 144.90 44.80 407.02 116.03 39.85 315.522002 135.87 42.89 379.33 141.28 43.54 397.21 124.19 41.59 340.482003 127.10 43.45 346.14 131.83 44.33 360.98 123.95 43.48 334.652004 128.19 44.99 346.07 132.04 44.86 360.33 124.14 47.89 323.792005 126.69 44.13 342.88 131.35 44.51 358.75 118.81 45.69 310.292006 126.52 44.24 342.00 130.66 45.16 354.53 125.54 45.32 335.612007 128.51 45.44 346.02 132.62 45.78 360.03 125.25 45.66 333.672008 128.80 45.68 346.45 131.86 45.70 357.48 129.04 45.44 347.942009 131.36 45.70 355.67 134.86 46.19 367.05 130.59 45.98 352.142010 127.49 44.41 345.03 131.24 45.22 356.50 123.85 44.63 331.302011 131.02 45.77 354.26 134.36 45.73 366.47 129.95 48.88 342.252012 130.95 44.52 357.26 133.55 45.16 365.02 135.24 42.78 377.342013 132.00 45.80 357.70 134.61 46.24 366.02 130.80 42.33 362.482014 132.26 46.19 357.66 135.14 46.05 368.42 128.60 46.16 344.47

Table 4.7Cancer of the Female Breast (Invasive)

Delay-adjusted SEER Incidencea Rates by Year, Race and Age

Page 8: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races, Females White Females Black Females All <50 50+ All <50 50+ All <50 50+

Year of Diagnosis:1975-2014 126.21 43.60 342.52 129.82 44.00 354.55 118.14 44.33 311.401975 105.08 40.64 273.82 107.39 40.72 281.95 93.57 42.97 226.091976 101.94 40.00 264.15 104.78 40.77 272.40 85.72 38.05 210.551977 100.80 39.09 262.40 103.34 39.28 271.08 87.14 37.87 216.141978 100.62 38.87 262.30 103.59 39.32 271.90 86.29 40.20 206.951979 102.09 38.01 269.90 104.70 38.61 277.77 86.94 37.76 215.711980 102.24 37.77 271.06 105.10 38.28 280.09 89.48 37.69 225.121981 106.36 39.21 282.19 109.91 40.10 292.72 94.35 38.86 239.641982 106.49 40.55 279.14 109.92 41.20 289.85 93.58 38.02 239.061983 111.12 40.25 296.72 114.40 40.82 307.08 103.82 41.70 266.471984 115.99 42.39 308.72 119.89 43.14 320.87 102.41 44.66 253.621985 124.26 44.34 333.52 127.80 44.38 346.21 111.54 45.52 284.411986 126.79 44.46 342.40 130.33 45.24 353.15 115.22 45.64 297.401987 134.50 45.53 367.47 140.24 46.48 385.75 109.55 43.28 283.081988 131.34 44.00 360.07 136.25 44.95 375.31 119.01 43.00 318.061989 127.25 43.40 346.80 132.40 44.51 362.54 105.20 42.26 270.031990 131.90 45.64 357.77 136.27 45.39 374.24 118.86 49.05 301.661991 133.86 47.26 360.63 138.89 47.24 378.89 117.72 51.29 291.671992 132.09 43.46 364.16 135.72 43.62 376.88 124.11 46.91 326.241993 129.20 42.86 355.30 133.10 43.25 368.39 119.53 45.29 313.931994 131.00 42.44 362.90 135.67 42.80 378.86 122.71 47.65 319.261995 132.70 43.21 367.03 137.63 43.71 383.57 123.85 45.63 328.681996 133.76 43.60 369.86 138.19 44.02 384.80 124.39 44.44 333.761997 138.06 43.56 385.52 142.59 44.06 400.61 126.41 44.96 339.701998 141.47 45.53 392.72 146.53 45.50 411.10 125.71 47.10 331.571999 141.49 43.84 397.19 147.02 45.08 413.96 126.29 44.11 341.492000 136.58 43.51 380.30 142.94 43.96 402.12 118.59 44.97 311.382001 138.83 43.99 387.16 144.90 44.80 407.02 116.03 39.85 315.522002 135.87 42.89 379.33 141.28 43.54 397.21 124.19 41.59 340.482003 127.10 43.45 346.14 131.83 44.33 360.98 123.95 43.48 334.652004 128.19 44.99 346.07 132.04 44.86 360.33 124.14 47.89 323.792005 126.69 44.13 342.88 131.35 44.51 358.75 118.81 45.69 310.292006 126.42 44.19 341.73 130.55 45.12 354.23 125.28 45.23 334.922007 128.29 45.35 345.48 132.40 45.70 359.43 124.76 45.49 332.322008 128.48 45.55 345.65 131.52 45.57 356.60 128.22 45.19 345.632009 130.93 45.53 354.56 134.40 46.02 365.82 129.58 45.66 349.342010 126.96 44.20 343.69 130.68 45.02 355.01 122.68 44.28 327.982011 130.38 45.51 352.62 133.68 45.48 364.63 128.40 48.34 338.042012 130.08 44.21 354.95 132.64 44.84 362.54 133.25 42.21 371.632013 130.85 45.39 354.63 133.29 45.78 362.45 128.53 41.61 356.152014 130.55 45.59 353.04 133.07 45.35 362.78 125.41 45.06 335.81

Table 4.8Cancer of the Female Breast (Invasive)

Age-adjusted SEER Incidencea Rates by Year, Race and Age

Page 9: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races, Females White Females Black Females All <50 50+ All <50 50+ All <50 50+

Year of Death:1975-2014 27.66 6.58 82.85 27.48 6.23 83.15 33.36 10.16 94.111975 31.45 9.11 89.94 31.79 9.01 91.42 29.49 10.68 78.751976 31.80 8.74 92.21 32.17 8.64 93.80 30.47 10.22 83.501977 32.48 8.86 94.34 32.67 8.75 95.32 32.80 10.52 91.131978 31.73 8.69 92.08 31.90 8.46 93.29 32.14 11.37 86.531979 31.21 8.58 90.47 31.48 8.34 92.07 30.82 11.36 81.781980 31.68 8.57 92.22 31.93 8.39 93.56 31.68 10.82 86.311981 31.92 8.46 93.33 32.12 8.20 94.77 32.55 11.48 87.741982 32.19 8.42 94.43 32.31 8.19 95.46 33.75 11.19 92.831983 32.07 8.16 94.70 32.20 7.89 95.85 33.53 11.17 92.101984 32.90 8.58 96.57 32.90 8.22 97.55 35.94 12.55 97.211985 32.98 8.56 96.90 33.11 8.30 98.09 34.85 12.04 94.581986 32.87 8.64 96.32 32.93 8.26 97.53 35.44 12.86 94.581987 32.66 8.44 96.08 32.57 7.99 96.93 36.73 12.94 99.041988 33.20 8.39 98.18 33.09 8.01 98.78 37.78 12.71 103.421989 33.23 8.42 98.22 33.23 8.06 99.16 36.61 12.41 99.961990 33.14 8.32 98.14 33.02 7.99 98.55 38.00 11.99 106.131991 32.69 8.16 96.91 32.45 7.73 97.15 38.28 12.31 106.291992 31.64 7.77 94.15 31.43 7.37 94.45 37.09 12.03 102.731993 31.39 7.41 94.18 31.09 6.99 94.20 38.04 11.65 107.141994 30.92 7.37 92.58 30.56 6.92 92.47 37.74 11.70 105.911995 30.55 7.29 91.46 30.09 6.80 91.07 38.18 11.71 107.491996 29.49 6.95 88.53 29.05 6.40 88.35 37.13 11.74 103.611997 28.21 6.71 84.53 27.62 6.22 83.64 37.43 11.03 106.561998 27.54 6.34 83.05 27.01 5.82 82.50 35.53 10.65 100.681999 26.61 5.75 81.22 25.98 5.20 80.40 35.21 10.27 100.522000 26.64 5.89 80.99 26.17 5.37 80.64 34.36 9.94 98.312001 26.01 5.86 78.77 25.43 5.36 77.98 34.52 9.85 99.122002 25.62 5.63 77.97 25.02 5.07 77.28 34.14 10.02 97.312003 25.27 5.58 76.85 24.66 5.08 75.90 34.10 9.62 98.192004 24.49 5.21 74.99 23.94 4.67 74.38 32.29 9.26 92.602005 24.14 5.20 73.74 23.49 4.65 72.83 32.81 9.46 93.952006 23.56 5.05 72.01 23.02 4.58 71.32 31.62 8.88 91.172007 22.96 4.77 70.60 22.40 4.28 69.85 31.36 8.55 91.102008 22.55 4.74 69.20 21.99 4.32 68.23 30.96 8.23 90.472009 22.24 4.81 67.88 21.76 4.48 67.01 30.19 7.96 88.392010 21.92 4.53 67.47 21.33 4.07 66.53 30.16 8.02 88.132011 21.54 4.47 66.25 20.93 4.03 65.19 30.15 7.83 88.612012 21.26 4.58 64.94 20.71 4.15 64.06 29.38 7.89 85.682013 20.73 4.41 63.47 20.29 4.07 62.75 28.20 7.32 82.882014 20.55 4.36 62.94 20.04 3.96 62.14 28.06 7.54 81.79

Table 4.9Cancer of the Female Breast (Invasive)

Age-adjusted U.S. Deatha Rates by Year, Race and Age

Page 10: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races, Females White Females Black Females All <50 50+ All <50 50+ All <50 50+

Year of Diagnosis:1975-2014 24.41 10.02 62.11 24.29 10.11 61.42 24.36 8.48 65.951975 5.83 3.78 11.19 5.89 3.82 11.33 3.94 - 8.311976 5.28 2.70 12.02 5.36 2.87 11.87 3.28 - 9.401977 4.25 2.56 8.68 4.33 2.60 8.85 3.17 - -1978 4.40 2.36 9.74 4.55 2.50 9.91 3.29 - -1979 4.58 2.81 9.21 4.65 2.85 9.37 4.78 - 9.551980 4.82 2.96 9.67 5.03 3.07 10.17 3.71 - -1981 4.97 2.64 11.05 4.93 2.52 11.26 4.11 - 8.841982 5.30 2.73 12.03 5.34 2.71 12.24 5.55 2.73 12.941983 6.09 3.03 14.09 6.22 3.03 14.57 5.41 - 13.201984 8.62 4.79 18.66 9.20 5.21 19.64 6.35 2.37 16.771985 11.53 5.92 26.24 12.10 6.27 27.36 8.21 3.49 20.571986 13.63 6.79 31.56 14.22 7.21 32.57 9.53 5.12 21.091987 17.38 7.82 42.39 18.24 8.27 44.33 12.30 5.64 29.731988 17.58 8.16 42.23 18.11 8.52 43.22 16.03 7.06 39.521989 16.54 7.02 41.48 17.10 7.27 42.84 14.64 5.52 38.531990 19.14 8.38 47.31 19.89 8.70 49.20 15.15 5.54 40.321991 19.79 8.79 48.62 20.50 8.90 50.87 15.41 7.29 36.661992 21.43 9.01 53.98 22.14 9.23 55.97 19.16 6.93 51.161993 20.70 8.36 53.04 21.36 8.79 54.30 16.62 6.06 44.271994 22.31 8.74 57.84 22.87 9.00 59.18 20.10 7.56 52.961995 24.72 9.63 64.24 25.09 10.00 64.61 22.80 6.50 65.501996 25.37 9.85 66.02 25.92 9.84 68.02 22.86 7.62 62.801997 28.35 11.08 73.60 28.91 11.22 75.21 28.45 11.39 73.111998 32.77 12.00 87.16 33.72 12.31 89.77 30.63 10.96 82.141999 32.75 11.99 87.11 33.19 12.24 88.05 29.61 10.47 79.722000 32.87 11.81 88.00 33.89 12.50 89.90 29.85 8.04 86.962001 33.69 11.59 91.57 34.23 12.04 92.31 31.92 9.09 91.692002 34.06 11.90 92.07 34.59 12.29 92.98 28.81 8.85 81.072003 32.50 12.03 86.09 33.48 12.52 88.38 30.17 9.43 84.482004 33.24 12.81 86.72 33.98 13.03 88.86 30.76 10.26 84.452005 32.65 12.50 85.40 33.56 13.00 87.40 32.33 10.43 89.702006 33.26 13.84 84.12 33.61 14.40 83.90 36.15 11.82 99.882007 35.38 14.37 90.39 35.82 14.84 90.74 33.71 11.01 93.172008 36.86 14.12 96.41 37.20 14.74 96.03 36.81 11.73 102.462009 37.02 14.42 96.18 37.78 14.98 97.48 35.60 11.46 98.802010 33.91 13.14 88.31 34.27 13.19 89.45 33.18 12.23 88.062011 35.63 14.42 91.17 36.02 14.82 91.52 33.99 10.85 94.572012 33.46 13.66 85.31 33.15 14.00 83.31 35.02 11.63 96.262013 34.93 14.46 88.55 34.43 14.51 86.60 36.97 12.21 101.812014 34.43 14.32 87.11 33.57 14.44 83.65 37.38 11.98 103.88

Table 4.10Cancer of the Female Breast (In Situ)

Age-adjusted SEER Incidencea Rates by Year, Race and Age

Page 11: SEER Cancer Statistics Review 1975-2014...Cancer of the Female Breast (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2014

SEE

R C

ancer Statistics Review

1975-2014N

ational Cancer Institute

a SEER 18 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),unless noted.

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130), unless noted.

c Rates are per 100,000 and are age-adjusted to the world (WHO 2000-2025) standard million.- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates, 2010-2014All ages 67.0 1.2 124.9 67.8 1.2 127.7 71.1 1.9 125.1Under 65 41.7 0.4 81.4 41.4 0.4 82.1 45.1 0.8 83.965 and over 242.2 6.4 425.5 249.7 6.5 442.9 251.1 9.7 410.1

All ages (WHO world std)c 52.3 0.9 98.7 52.7 0.8 100.6 55.7 1.4 99.4

Age-Specific Rates, 2010-2014<1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 0.1 - 0.2 - - - - - -20-24 0.7 - 1.5 0.7 - 1.5 0.9 - 1.825-29 4.5 - 9.2 4.3 - 8.8 6.4 - 12.530-34 13.6 - 27.3 13.0 - 26.5 17.4 - 33.335-39 30.6 0.2 60.8 29.7 0.2 60.2 35.6 - 67.240-44 61.9 0.5 122.7 61.1 0.4 123.3 65.0 1.0 122.545-49 95.4 0.8 188.4 94.7 0.7 189.9 98.3 1.3 185.550-54 114.7 1.1 224.7 114.2 1.0 226.6 121.0 2.1 227.355-59 136.1 1.7 262.8 135.9 1.6 266.0 149.9 3.4 276.860-64 178.0 2.9 338.6 179.4 2.9 346.0 193.0 4.4 347.065-69 227.0 5.2 424.0 231.7 5.1 438.1 233.9 9.4 408.370-74 248.2 6.1 451.6 256.3 6.2 470.9 249.6 8.9 424.175-79 257.6 6.6 451.9 268.2 6.7 475.5 266.9 9.0 435.680-84 248.3 7.9 412.9 257.4 8.0 432.0 257.9 12.0 394.685+ 229.7 7.9 343.5 235.2 8.2 352.2 256.7 10.9 359.3

U.S. MortalityAge at DeathAge-Adjusted Rates, 2010-2014All ages 11.8 0.3 21.2 11.4 0.3 20.6 17.1 0.5 29.2Under 65 5.3 0.1 10.3 4.9 0.1 9.7 8.9 0.2 16.565 and over 56.5 1.7 96.2 56.3 1.6 96.5 73.9 2.8 116.9

All ages (WHO world std)c 8.4 0.2 15.4 8.0 0.2 14.9 12.5 0.4 21.8

Age-Specific Rates, 2010-2014<1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 0.0 - 0.1 0.0 - 0.1 - - -25-29 0.3 - 0.7 0.3 - 0.6 0.7 - 1.330-34 1.3 - 2.6 1.1 - 2.3 2.7 - 5.235-39 3.3 0.0 6.5 2.9 - 5.9 6.1 - 11.440-44 6.4 0.1 12.7 5.7 0.0 11.5 12.0 - 22.545-49 10.1 0.2 19.8 9.1 0.1 18.2 17.6 0.4 32.850-54 15.3 0.2 29.8 14.2 0.2 27.9 25.3 0.5 47.255-59 20.6 0.4 39.7 19.3 0.3 37.6 33.4 0.6 61.460-64 27.1 0.7 51.5 26.0 0.6 49.9 41.1 1.1 73.765-69 34.5 0.9 64.6 33.9 0.9 64.1 48.7 1.8 84.970-74 42.6 1.3 77.7 42.1 1.2 77.6 58.3 2.6 98.375-79 54.3 1.6 95.5 54.2 1.5 96.3 70.5 2.9 114.080-84 72.2 2.4 120.2 72.1 2.4 121.0 94.5 4.2 143.685+ 119.3 3.3 177.6 120.0 3.3 179.4 143.7 3.7 200.4

Table 4.11Cancer of the Breast (Invasive)

SEER Incidencea and U.S. Deathb Rates, Age-Adjusted and Age-Specific Rates, by Race and Sex

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a SEER 18 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),unless noted.

b Rates are per 100,000 and are age-adjusted to the world (WHO 2000-2025) standard million.- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races, Females White Females Black Females Age-Adjusted Rates, 2010-2014Age at Diagnosis:

All ages 31.2 31.0 31.4Under 65 23.1 23.0 21.765 and over 87.0 86.2 98.3

All ages (WHO world std)b 25.3 25.2 25.4

Age-Specific Rates, 2010-2014Age at Diagnosis:

<1 - - -1-4 - - -5-9 - - -10-14 - - -15-19 - - -20-24 0.2 0.2 -25-29 0.7 0.6 0.830-34 2.6 2.3 3.635-39 10.1 10.0 9.440-44 40.6 40.8 34.045-49 62.1 62.8 49.250-54 70.5 71.1 62.155-59 73.2 72.0 78.360-64 86.3 84.4 99.665-69 108.3 106.4 120.670-74 103.1 102.2 113.175-79 88.1 87.7 107.480-84 65.0 65.4 71.585+ 30.0 30.0 33.9

Table 4.12Cancer of the Female Breast(In Situ)

SEER Incidencea Rates, Age-Adjusted and Age-Specific Rates, by Race

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a Based on End Results data from a series of hospital registries and one population-based registry.b SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).

Based on follow-up of patients into 2014.c SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,

Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG).Based on follow-up of patients into 2014.

d Period survival provides a 2013 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts. It is computed here using three year calendar blocks (2010-2012: 0-1 year survival),(2009-2011: 1-2 year survival), (2008-2010: 2-3 year survival), (2007-2009: 3-4 year survival), (2006-2008: 4-5 years survival).

e Stage at diagnosis is classified using SEER Summary Stage 2000. Stage distribution percentages may not sum to 100 due to rounding.f The difference between 1975-1977 and 2007-2013 is statistically significant (p<.05).g The standard error is between 5 and 10 percentage points.h The standard error is greater than 10 percentage points.j In situ cases are not included in the All Stages group.- Statistic could not be calculated due to fewer than 25 cases during the time period.

All Races, Females White Females Black Females All <50 50+ All <50 50+ All <50 50+

5-Year Relative Survival (Percent)Year of Diagnosis:1960-1963a - - - 63 - - 46 - -1970-1973a - - - 68 - - 51 - -1975-1977b 74.8 76.5 74.3 75.6 77.8 74.9 62.2 62.4 62.01978-1980b 74.4 75.5 74.1 75.1 76.1 74.9 63.4 67.1 61.51981-1983b 76.1 77.4 75.7 77.1 78.5 76.7 63.4 65.1 62.61984-1986b 78.9 77.8 79.3 80.0 79.5 80.2 65.1 63.9 65.81987-1989b 84.0 81.4 85.0 85.1 82.7 85.9 71.1 69.6 71.91990-1992b 85.2 83.4 85.9 86.5 85.1 87.0 71.5 70.2 72.31993-1995b 86.4 84.3 87.1 87.6 86.2 88.1 72.7 70.4 74.11996-1998b 88.2 86.6 88.8 89.4 88.3 89.7 76.2 74.0 77.61999-2001b 89.7 88.1 90.3 90.8 89.9 91.1 78.9 76.9 80.12002-2006b 90.2 89.9 90.4 91.7 91.7 91.7 77.9 78.5 77.72007-2013b 91.1f 91.1f 91.1f 92.2f 92.3f 92.1f 82.7f 83.4f 82.4f

5-Year Period Survival (Percent)cd

2013 89.8 89.6 89.9 90.8 90.8 90.9 80.8 80.5 81.0

Stage Distribution (%) 2007-2013ce

All StagesNumber of cases 338,602 79,376 259,226 268,724 58,666 210,058 37,618 10,658 26,960Percent 100% 100% 100% 100% 100% 100% 100% 100% 100%Localized 62 54 64 63 55 65 53 47 56Regional 31 39 28 30 39 28 36 44 33Distant 6 5 6 5 5 6 9 8 9Unstaged 2 1 2 1 1 2 2 1 2

5-Year Relative Survival (Percent), 2007-2013c

Age at Diagnosis:Ages <45 88.1 - - 89.5 - - 78.3 - -Ages 45-54 90.6 - - 91.7 - - 82.1 - -Ages 55-64 90.1 - - 91.2 - - 81.7 - -Ages 65-74 91.4 - - 92.2 - - 83.6 - -Ages 75+ 87.1 - - 88.3 - - 73.8 - -Ages <65 89.9 - - 91.0 - - 81.0 - -Ages 65+ 89.5 - - 90.5 - - 79.7 - -

Stagee:All Stages 89.7 89.5 89.8 90.8 90.8 90.8 80.6 80.4 80.7Localized 98.9 97.0 99.4 99.4 97.4 99.9 94.8 93.5 95.3Regional 85.2 86.6 84.6 86.4 88.1 85.8 76.1 76.7 75.8Distant 26.9 37.1 24.1 27.9 39.8 25.0 19.7 25.8 17.5Unstaged 53.2 75.3 48.0 50.8 76.0 45.8 48.5 63.6 43.4In Situ j 100.0 100.0 100.0 100.0 100.0 100.0 100.0 99.7 100.0

Table 4.13Cancer of the Female Breast (Invasive)

5-Year Relative and Period Survival (Percent) by Race, Diagnosis Year, Stage and Age

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1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

Survival Time

1-year 94.4 95.1 96.3 97.1 97.1 97.0 97.4 97.5 97.5 97.5 97.3 97.5 97.8 97.7 97.8 97.7 97.7 97.7 97.9 97.6 97.8 98.0 97.92-year 88.7 89.9 92.3 93.8 94.0 93.7 94.4 94.9 95.1 95.3 95.1 95.4 95.5 95.6 95.7 95.7 96.0 95.7 96.0 95.8 96.0 95.93-year 83.1 84.6 88.3 90.4 91.3 90.9 92.0 92.9 93.1 93.4 92.8 93.5 93.3 93.3 93.8 93.8 94.0 93.8 93.9 93.9 94.34-year 78.4 80.2 85.0 87.8 88.8 88.9 89.9 91.0 91.2 91.6 91.0 91.7 91.5 91.4 91.9 92.3 92.4 92.3 92.4 92.15-year 74.6 76.3 82.2 85.6 86.8 86.7 88.4 89.5 89.5 90.2 89.4 90.2 89.8 89.9 90.5 90.7 91.2 90.6 91.36-year 71.4 73.4 79.9 83.8 85.4 85.0 86.9 88.3 88.0 89.0 88.2 88.8 88.6 88.6 89.2 89.6 89.8 89.47-year 68.7 70.6 77.8 82.1 83.8 83.8 85.9 87.1 86.9 87.7 86.8 87.6 87.4 87.4 88.0 88.6 88.88-year 66.4 68.4 76.3 80.9 82.6 82.4 84.9 85.8 85.8 86.3 85.9 86.4 86.3 86.5 87.3 87.69-year 64.3 66.4 74.6 79.7 81.3 81.4 83.7 84.6 84.9 85.2 85.2 85.6 85.9 85.5 86.510-year 62.5 64.5 73.3 78.7 80.5 80.3 82.6 83.4 84.1 84.5 84.4 85.0 84.6 84.711-year 60.8 62.7 72.1 77.6 79.5 79.5 81.7 82.6 82.9 83.5 83.5 84.4 83.812-year 59.3 61.5 70.9 76.7 78.5 78.6 81.0 82.0 82.3 82.5 82.4 83.313-year 58.1 60.4 69.8 75.8 77.4 77.5 80.0 81.1 81.6 81.7 81.714-year 57.1 59.2 69.0 74.9 76.8 76.8 79.3 80.4 80.5 81.115-year 56.1 58.3 68.1 74.1 75.9 76.2 78.4 79.3 80.116-year 55.1 57.2 67.2 73.2 74.9 75.5 77.3 78.717-year 54.2 56.3 66.5 72.3 74.0 74.8 76.918-year 53.4 55.6 65.7 71.6 72.8 74.019-year 52.6 54.9 65.1 70.9 72.220-year 51.9 54.2 64.5 70.121-year 51.2 53.5 63.722-year 50.6 52.8 63.223-year 50.0 52.2 62.524-year 49.4 51.5 61.925-year 48.6 51.0 61.226-year 48.3 50.727-year 48.0 50.028-year 47.5 49.429-year 47.0 48.630-year 46.6 47.9

Table 4.14Cancer of the Female Breast (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races, Females

Year of Diagnosis

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1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

Survival Time

1-year 96.6 97.4 97.9 98.0 97.9 97.7 98.0 98.3 98.6 98.4 98.2 98.5 98.7 98.5 98.8 98.8 99.0 98.7 98.8 98.6 99.0 98.8 98.52-year 90.7 91.2 92.5 93.8 93.6 93.8 94.7 95.1 95.0 95.5 94.6 95.7 96.0 95.9 96.1 96.7 97.1 96.4 96.5 96.3 97.1 96.53-year 84.5 85.5 87.3 89.7 90.0 90.8 91.6 92.2 92.2 93.0 91.6 93.2 93.7 93.3 93.8 94.8 95.0 94.1 94.3 93.9 95.14-year 79.9 80.9 83.3 86.3 86.6 88.1 88.7 89.5 90.0 90.5 89.3 90.6 91.8 91.2 92.2 93.1 93.4 92.4 92.6 91.85-year 76.1 77.0 80.1 83.8 84.1 85.5 86.7 87.3 88.1 89.0 87.4 88.7 89.8 89.4 90.7 91.2 91.9 90.8 91.06-year 73.2 74.2 77.9 81.7 82.2 83.3 84.7 85.4 86.1 87.3 85.3 86.8 88.1 87.9 89.4 89.6 90.3 89.47-year 70.8 71.6 75.8 80.0 80.2 81.7 83.2 83.7 84.8 85.6 83.6 85.3 86.8 86.3 88.2 88.7 89.08-year 68.9 69.5 74.1 78.5 78.7 80.1 81.5 82.3 83.6 83.8 82.1 84.2 85.6 85.2 87.4 87.59-year 67.0 67.8 72.6 77.3 77.6 79.0 80.5 80.8 82.5 82.5 81.0 83.2 84.9 84.2 86.410-year 65.6 66.4 71.5 76.3 76.3 77.7 79.2 79.8 81.5 81.6 80.2 82.3 83.9 83.311-year 64.2 65.0 70.4 75.4 75.5 76.7 78.2 78.9 80.3 80.8 79.3 81.6 82.912-year 62.8 64.0 69.3 74.4 74.6 76.0 77.3 78.2 79.9 80.0 78.4 80.513-year 61.7 63.1 68.3 73.5 73.7 74.7 76.4 77.5 79.2 79.2 77.614-year 61.0 62.0 67.6 72.8 73.0 74.0 75.4 77.2 78.0 78.815-year 60.2 61.2 66.9 72.1 72.3 73.4 74.7 76.6 77.416-year 59.5 60.5 66.2 71.4 71.5 72.9 74.0 76.017-year 58.9 59.8 65.6 70.8 70.4 72.3 73.618-year 58.4 59.2 65.0 70.1 69.3 71.919-year 57.7 58.8 64.4 69.6 68.420-year 57.1 58.2 63.9 69.121-year 56.4 57.5 63.422-year 55.8 56.7 62.923-year 55.3 56.2 62.424-year 54.7 55.6 62.025-year 54.1 55.1 61.526-year 53.8 54.627-year 53.2 54.128-year 52.8 53.529-year 52.4 53.030-year 52.1 52.5

Table 4.15Cancer of the Female Breast (Ages <50, Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races, Females

Year of Diagnosis

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1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

Survival Time

1-year 93.7 94.4 95.8 96.8 96.8 96.7 97.2 97.2 97.2 97.2 97.0 97.2 97.5 97.5 97.4 97.4 97.3 97.4 97.6 97.3 97.4 97.8 97.82-year 88.0 89.6 92.3 93.8 94.1 93.6 94.3 94.9 95.2 95.3 95.2 95.4 95.2 95.5 95.6 95.3 95.7 95.5 95.9 95.6 95.6 95.73-year 82.6 84.3 88.6 90.7 91.8 91.0 92.1 93.1 93.4 93.6 93.2 93.6 93.1 93.3 93.8 93.4 93.6 93.7 93.8 93.9 94.14-year 77.9 79.9 85.6 88.4 89.6 89.1 90.3 91.6 91.7 92.0 91.5 92.1 91.5 91.5 91.8 92.0 92.1 92.3 92.4 92.25-year 74.1 76.1 83.0 86.3 87.8 87.1 89.0 90.3 90.1 90.6 90.2 90.7 89.8 90.1 90.5 90.6 90.9 90.6 91.46-year 70.8 73.1 80.5 84.6 86.6 85.6 87.8 89.4 88.7 89.6 89.2 89.5 88.8 88.9 89.1 89.7 89.6 89.37-year 67.9 70.4 78.6 82.9 85.1 84.6 86.8 88.4 87.7 88.4 88.0 88.4 87.7 87.9 87.9 88.6 88.88-year 65.6 68.0 77.1 81.9 84.1 83.3 86.3 87.1 86.6 87.3 87.2 87.2 86.6 87.0 87.3 87.69-year 63.3 65.9 75.3 80.7 82.7 82.3 84.9 86.1 85.8 86.3 86.8 86.4 86.2 86.1 86.510-year 61.3 63.8 73.9 79.6 82.2 81.4 83.9 84.8 85.0 85.5 85.9 86.0 84.9 85.211-year 59.5 61.9 72.7 78.5 81.0 80.6 83.1 84.0 83.8 84.6 85.1 85.3 84.212-year 58.0 60.6 71.4 77.6 79.9 79.6 82.5 83.6 83.2 83.4 83.8 84.413-year 56.7 59.4 70.3 76.6 78.8 78.7 81.4 82.4 82.5 82.6 83.314-year 55.6 58.1 69.4 75.7 78.3 78.0 80.9 81.6 81.5 81.915-year 54.4 57.2 68.4 74.8 77.3 77.3 79.7 80.3 81.116-year 53.4 55.9 67.5 73.9 76.2 76.6 78.6 79.617-year 52.2 54.8 66.6 72.8 75.4 75.7 78.118-year 51.3 54.1 65.8 72.0 74.1 74.719-year 50.4 53.3 65.1 71.3 73.720-year 49.5 52.4 64.4 70.321-year 48.8 51.7 63.622-year 48.3 51.0 63.023-year 47.7 50.4 62.224-year 47.0 49.6 61.425-year 46.1 49.1 60.526-year 45.7 48.927-year 45.4 48.128-year 45.0 47.529-year 44.3 46.330-year 43.9 45.3

Table 4.16Cancer of the Female Breast (Ages 50+, Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races, Females

Year of Diagnosis

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Devcan 6.7.5, April 2017, National Cancer Institute (https://surveillance.cancer.gov/devcan/).Source: Incidence data are from the SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta,

San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey,and Georgia excluding ATL/RG). Mortality data are from the NCHS public use data file for the total US.

a Underlying incidence and mortality data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties.

b Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

- Statistic could not be calculated.A percent of 0.00 represents a value that is below 0.005.

Risk of Being Risk of Being

Race/ Current Diagnosed with Cancer Risk of Dying Race/ Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 0.00 0.00 0.06 12.41 2.62 Asian/ 0 0.00 0.00 0.06 10.54 1.75

10 0.00 0.07 0.52 12.53 2.65 Pacific 10 0.00 0.06 0.48 10.61 1.77

20 0.06 0.52 1.96 12.56 2.66 Islander 20 0.06 0.48 1.90 10.62 1.77

30 0.45 1.90 4.11 12.56 2.67 30 0.43 1.85 3.81 10.59 1.77

40 1.47 3.70 6.84 12.25 2.64 40 1.43 3.41 5.95 10.25 1.74

50 2.31 5.54 8.81 11.14 2.53 50 2.02 4.63 7.02 9.02 1.65

60 3.45 6.93 8.91 9.41 2.30 60 2.71 5.20 6.72 7.28 1.46

70 3.95 6.18 - 6.76 1.95 70 2.68 4.32 - 4.92 1.21

80 2.96 - - 3.72 1.52 80 1.92 - - 2.62 0.95

White 0 0.00 0.00 0.06 12.68 2.59 American 0 0.00 0.01 0.05 7.68 1.63

10 0.00 0.06 0.51 12.79 2.62 Indian/ 10 0.01 0.05 0.36 7.75 1.65

20 0.06 0.51 1.96 12.81 2.62 Alaska 20 0.05 0.36 1.11 7.77 1.66

30 0.45 1.91 4.14 12.82 2.63 Nativea 30 0.31 1.07 2.51 7.80 1.67

40 1.48 3.74 6.95 12.52 2.61 40 0.78 2.24 4.55 7.65 1.67

50 2.33 5.65 9.05 11.40 2.51 50 1.53 3.93 5.89 7.14 1.64

60 3.54 7.16 9.18 9.66 2.30 60 2.56 4.65 5.68 5.99 1.54

70 4.11 6.40 - 6.95 1.95 70 2.37 3.53 - 3.89 1.30

80 3.04 - - 3.77 1.51 80 1.54 - - 2.00 1.09

Black 0 0.00 0.00 0.08 11.39 3.16 Hispanicb 0 0.00 0.00 0.05 9.93 2.14

10 0.00 0.09 0.57 11.60 3.22 10 0.00 0.05 0.41 10.01 2.16

20 0.08 0.57 1.96 11.62 3.23 20 0.05 0.41 1.54 10.02 2.17

30 0.49 1.89 4.12 11.62 3.24 30 0.36 1.49 3.26 10.01 2.17

40 1.43 3.69 6.62 11.33 3.20 40 1.14 2.93 5.41 9.73 2.14

50 2.36 5.42 8.23 10.32 3.02 50 1.83 4.37 6.76 8.79 2.04

60 3.34 6.42 8.16 8.71 2.69 60 2.66 5.17 6.75 7.29 1.85

70 3.64 5.70 - 6.35 2.26 70 2.75 4.49 - 5.08 1.58

80 2.88 - - 3.80 1.82 80 2.13 - - 2.86 1.27

Table 4.17

Cancer of the Female Breast (Invasive)

Risk of Being Diagnosed With Cancer in 10, 20 and 30 Years,

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age, and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females, 2012-2014 By Race/Ethnicity

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SEER Cancer Statistics Review 1975-2014 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval. The AAPCs are calculated bythe Joinpoint Regression Program Version 4.3.0.0, April 2016, National Cancer Institute.

- Statistic not shown. Rate based on less than 16 cases for the time interval.Trend based on less than 10 cases for at least one year within the time interval.

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle,Utah, and Atlanta.The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the AlaskaNative Registry, and Rural Georgia.The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky,Louisiana, New Jersey, and Georgia excluding ATL/RG.

c The 2005-2014 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2014.

d The 2005-2014 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2014.

e Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/PacificIslanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry. The 2005-2014 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

f Incidence data for American Indian/Alaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties.

g US Mortality Files, National Center for Health Statistics, CDC.h The 2005-2014 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2014.* The APC is significantly different from zero (p<.05).

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2010-2014 Trend 2005-2014c Trend 2005-2014d

Rate per 100,000 persons AAPC (%) AAPC (%)

Females Females Females RACE/ETHNICITY

All Races 124.9 0.2 0.3

White 127.7 0.0 0.1White Hispanice 96.6 0.2 -White Non-Hispanice 134.1 0.1 -

Black 125.1 0.2* 0.3*

Asian/Pacific Islander 98.5 1.2* -

Amer Ind/Alaska Natf 82.2 0.1 -

Hispanice 93.1 0.2 -

U.S. Mortalityg Rate 2010-2014 Trend 2005-2014h

Rate per 100,000 persons AAPC (%)

Females FemalesRACE/ETHNICITY

All Races 21.2 -1.8*

White 20.6 -1.9*White Hispanice 15.2 -0.6White Non-Hispanice 21.2 -1.8*

Black 29.2 -1.5*

Asian/Pacific Islander 11.3 -0.9*

Amer Ind/Alaska NatTotal U.S. 10.8 -1.8*CHSDA Counties 14.1 -3.1*Non-CHSDA Counties 7.2 -3.1*

Hispanice 14.4 -0.6

Table 4.18Cancer of the Female Breast (Invasive)

SEER Incidence and U.S. MortalityAge-Adjusted Rates and Trendsa

By Race/Ethnicity

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SEER Cancer Statistics Review 1975-2014 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval. The AAPCs are calculated bythe Joinpoint Regression Program Version 4.3.0.0, April 2016, National Cancer Institute.

- Statistic not shown. Rate based on less than 16 cases for the time interval.Trend based on less than 10 cases for at least one year within the time interval.

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle,Utah, and Atlanta.The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the AlaskaNative Registry, and Rural Georgia.The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky,Louisiana, New Jersey, and Georgia excluding ATL/RG.

c The 2005-2014 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2014.

d The 2005-2014 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2014.

e Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/PacificIslanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry.

f Incidence data for American Indian/Alaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties.

* The APC is significantly different from zero (p<.05).

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2010-2014 Trend 2005-2014c Trend 2005-2014d

Rate per 100,000 persons AAPC (%) AAPC (%)

Females Females Females RACE/ETHNICITY

All Races 31.2 0.4 0.5*

White 31.0 -0.5 -0.5White Hispanice 22.3 1.7* -White Non-Hispanice 33.1 -0.1 -

Black 31.4 1.6* 1.5*

Asian/Pacific Islander 30.7 1.3* -

Amer Ind/Alaska Natf 17.6 1.7* -

Hispanice 21.6 1.6* -

Table 4.19Cancer of the Female Breast (In Situ)

SEER IncidenceAge-Adjusted Rates and Trendsa

By Race/Ethnicity

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a Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah and Atlanta.

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska Native Registry and Rural Georgia.The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+

SEER Incidence Ratesa, 2010-2014

California 120.70 41.06 329.26 125.25 41.18 345.41 123.00 40.76 338.37Greater Bay Area 124.62 44.63 334.10 133.33 45.69 362.82 126.23 40.21 351.45San Francisco-Oakland 126.94 45.02 341.45 134.66 45.34 368.54 126.62 40.62 351.80San Jose-Monterey 120.20 43.93 319.92 131.09 46.32 353.07 125.95 37.94 356.42

Los Angeles 114.65 40.53 308.75 117.06 39.21 320.93 126.85 42.79 346.95Greater California 122.09 40.01 337.03 126.24 40.79 349.98 117.01 39.13 320.97

Connecticut 139.19 51.87 367.84 141.79 53.84 372.08 116.01 39.12 317.33Detroit 131.59 45.72 356.43 132.46 45.72 359.60 132.14 46.95 355.24Georgia 123.54 42.88 334.76 123.86 41.47 339.60 125.45 46.69 331.70Atlanta 131.92 45.74 357.60 137.62 47.12 374.59 130.82 46.26 352.25Rural Georgia 124.13 47.80 324.01 128.94 47.78 341.47 113.23 44.42 293.43Greater Georgia 119.36 41.00 324.56 118.61 38.93 327.23 121.97 47.11 318.01

Hawaii 135.98 51.68 356.71 145.16 56.41 377.57 118.44 59.80 271.99Iowa 122.76 41.46 335.66 123.77 42.21 337.35 103.13 34.03 284.08Kentucky 123.33 41.84 336.72 123.41 41.60 337.64 126.21 44.43 340.35Louisiana 123.23 42.29 335.19 120.99 40.15 332.68 131.59 47.57 351.62New Jersey 132.02 48.62 350.43 135.87 50.09 360.48 120.25 44.29 319.17New Mexico 112.08 35.47 312.71 117.04 37.88 324.35 86.16 21.73 254.88Seattle-Puget Sound 139.91 46.68 384.04 144.18 46.72 399.38 129.14 42.80 355.22Utah 114.72 36.52 319.51 115.87 36.89 322.69 76.46 - 195.53

SEER 9 Areasb 129.80 44.98 351.92 132.72 45.31 361.60 127.67 44.28 346.05SEER 13 Areasb 125.85 43.86 340.53 129.25 43.88 352.78 127.38 43.92 345.94SEER 18 Areasb 124.92 43.10 339.18 127.71 43.13 349.19 125.13 44.44 336.42

Table 4.20Cancer of the Female Breast (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry, Race and Age

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a US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah and Atlanta.The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska Native Registry and Rural Georgia.The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+

SEER Death Ratesa, 2010-2014

California 20.45 4.29 62.75 21.38 4.22 66.34 30.17 8.12 87.92Greater Bay Area 18.88 3.71 58.60 20.68 3.51 65.62 27.60 7.57 80.04San Francisco-Oakland 19.45 3.91 60.16 20.82 3.44 66.35 28.06 7.78 81.16San Jose-Monterey 17.78 3.35 55.57 20.43 3.64 64.39 23.82 - 69.57

Los Angeles 21.06 4.58 64.20 21.55 4.30 66.72 32.21 8.59 94.05Greater California 20.71 4.36 63.53 21.50 4.37 66.36 29.32 7.91 85.38

Connecticut 19.10 4.10 58.39 18.91 3.80 58.49 22.12 6.86 62.08Detroit 23.99 5.13 73.39 22.36 4.52 69.07 30.71 7.20 92.28Georgia 22.56 4.99 68.56 20.39 3.91 63.56 28.92 7.42 85.21Atlanta 23.37 5.13 71.13 19.73 3.56 62.08 31.15 7.51 93.07Rural Georgia 26.90 - 84.24 22.88 - 75.69 33.15 - 99.05Greater Georgia 22.11 4.90 67.19 20.62 4.07 63.94 27.38 7.31 79.92

Hawaii 15.04 4.15 43.55 18.33 4.41 54.79 - - -Iowa 19.35 4.01 59.52 19.42 4.04 59.69 23.03 - 66.12Kentucky 21.87 4.59 67.14 21.46 4.36 66.22 28.34 7.82 82.07Louisiana 24.23 5.14 74.23 20.23 3.48 64.09 34.76 8.68 103.06New Jersey 22.89 4.42 71.26 22.47 4.02 70.81 30.78 7.72 91.16New Mexico 19.33 4.60 57.90 20.03 4.93 59.57 28.60 - 89.69Seattle-Puget Sound 20.22 3.46 64.12 21.13 3.46 67.38 23.67 6.26 69.23Utah 20.77 3.93 64.85 20.90 3.84 65.57 - - -

SEER 9 Areasb 20.37 4.25 62.60 20.35 3.89 63.46 28.82 7.24 85.31SEER 13 Areasb 20.39 4.25 62.66 20.61 3.95 64.25 29.57 7.49 87.40SEER 18 Areasb 21.16 4.40 65.04 21.09 4.07 65.65 30.07 7.70 88.63

Total U.S. 21.19 4.47 64.96 20.65 4.06 64.09 29.16 7.72 85.30

Table 4.21Cancer of the Female Breast (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry, Race and Age

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a Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah and Atlanta.

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska Native Registry and Rural Georgia.The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+ All Ages Ages <50 Ages 50+

SEER Incidence Ratesa, 2010-2014

California 28.35 10.54 74.97 27.69 10.18 73.56 28.85 8.09 83.21Greater Bay Area 33.24 13.53 84.86 32.76 13.18 84.04 26.34 8.07 74.16San Francisco-Oakland 34.93 14.44 88.57 34.05 14.02 86.52 27.69 8.45 78.07San Jose-Monterey 30.07 11.88 77.69 30.55 11.74 79.81 17.10 - 46.65

Los Angeles 25.56 9.31 68.12 24.37 8.68 65.45 29.00 7.99 84.02Greater California 27.94 10.08 74.70 27.63 10.00 73.81 29.69 8.20 85.95

Connecticut 44.56 20.50 107.55 45.29 21.61 107.30 38.41 13.94 102.49Detroit 36.44 13.93 95.38 36.95 15.09 94.21 36.24 10.75 102.99Georgia 30.05 11.48 78.67 29.89 11.68 77.56 31.68 11.21 85.30Atlanta 36.00 13.81 94.09 37.89 15.34 96.94 35.80 12.59 96.58Rural Georgia 25.83 8.31 71.70 24.02 - 69.69 27.84 - 75.46Greater Georgia 27.16 10.08 71.88 27.00 10.19 71.02 28.46 9.85 77.20

Hawaii 34.84 14.80 87.34 30.85 14.29 74.20 - - -Iowa 27.47 10.39 72.20 27.49 10.42 72.17 30.66 13.61 75.29Kentucky 26.35 9.60 70.21 26.06 9.77 68.72 32.16 8.03 95.34Louisiana 25.24 8.29 69.60 25.24 8.67 68.61 26.21 7.59 74.96New Jersey 41.49 19.12 100.07 42.79 20.01 102.44 33.10 12.73 86.44New Mexico 21.59 8.15 56.77 22.55 8.73 58.71 20.48 - 60.62Seattle-Puget Sound 38.30 15.10 99.03 37.74 14.68 98.13 43.37 13.00 122.88Utah 23.83 9.07 62.48 24.10 9.20 63.13 39.00 - -

SEER 9 Areasb 34.47 14.00 88.09 34.27 14.19 86.86 35.41 11.78 97.29SEER 13 Areasb 32.13 12.72 82.96 31.86 12.70 82.02 33.72 10.93 93.39SEER 18 Areasb 31.17 12.24 80.72 31.01 12.29 80.02 31.38 10.23 86.75

Table 4.22Cancer of the Female Breast (In Situ)

Age-Adjusted SEER Incidence Ratesa

By Registry, Race and Age

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SEER Cancer Statistics Review 1975-2014 National Cancer Institute

a US Mortality Files, National Center for Health Statistics, Centers for Disease Control andPrevention. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130).

b Difference between state rate and total U.S. rate is statistically significant (p<=.0002).c Absolute percent difference between state rate and total U.S. rate is 10% or more.d Rank of state level death rate and the 95% confidence intervals (low, high) for the rank.SE Standard error of the rate.PD Percent difference between state rate and total U.S. rate.- Statistic not shown. Rate based on less than 16 cases for the time interval.

State Rate SE Rank(CI)d PD TOTAL U.S. 21.19 0.05

High Five StatesD.C. 29.30 1.33 01(01,01) 38.31c

Louisiana 24.23 0.43 02(02,08) 14.38c

Mississippi 23.91 0.53 03(02,14) 12.86c

Oklahoma 23.40 0.46 04(02,18) 10.47c

Ohio 23.11 0.25 05(03,15) 9.09

Low Five StatesMassachusetts 18.78 0.30 47(37,50) -11.36c

Vermont 18.63 0.96 48(22,50) -12.08c

Maine 17.99 0.62 49(35,50) -15.10c

North Dakota 17.76 0.92 50(28,51) -16.16c

Hawaii 15.04 0.60 51(50,51) -29.02c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 21.98 0.39 18(05,27) 3.75 Montana 20.18 0.81 34(10,49) -4.75Alaska 20.45 1.23 29(02,50) -3.49 Nebraska 20.12 0.61 36(17,48) -5.01Arizona 19.48 0.32 39(29,48) -8.05 Nevada 22.67 0.56 09(02,25) 7.03Arkansas 22.14 0.50 15(03,29) 4.51 New Hampshire 20.25 0.70 32(13,48) -4.40California 20.45 0.14 28(24,37) -3.48 New Jersey 22.89 0.29 06(03,19) 8.04Colorado 19.20 0.37 42(32,50) -9.40 New Mexico 19.33 0.57 41(25,50) -8.76Connecticut 19.10 0.41 43(31,50) -9.84 New York 20.66 0.18 26(23,36) -2.50Delaware 21.92 0.87 20(02,40) 3.45 North Carolina 21.62 0.27 23(11,28) 2.03D.C. 29.30 1.33 01(01,01) 38.31c North Dakota 17.76 0.92 50(28,51) -16.16c

Florida 20.22 0.18 33(25,40) -4.57 Ohio 23.11 0.25 05(03,15) 9.09Georgia 22.56 0.29 10(04,22) 6.48 Oklahoma 23.40 0.46 04(02,18) 10.47c

Hawaii 15.04 0.60 51(50,51) -29.02c Oregon 20.78 0.42 24(16,40) -1.90Idaho 20.36 0.69 31(12,49) -3.90 Pennsylvania 22.19 0.23 14(07,24) 4.73Illinois 22.50 0.24 12(04,21) 6.19 Rhode Island 18.84 0.75 45(24,50) -11.07c

Indiana 21.84 0.34 22(07,27) 3.11 South Carolina 22.69 0.40 08(03,23) 7.08Iowa 19.35 0.45 40(26,49) -8.65 South Dakota 20.16 0.90 35(07,50) -4.86Kansas 20.10 0.49 37(21,47) -5.11 Tennessee 22.13 0.34 16(05,25) 4.46Kentucky 21.87 0.41 21(06,28) 3.24 Texas 20.39 0.18 30(24,38) -3.77Louisiana 24.23 0.43 02(02,08) 14.38c Utah 20.77 0.59 25(11,45) -1.98Maine 17.99 0.62 49(35,50) -15.10c Vermont 18.63 0.96 48(22,50) -12.08c

Maryland 22.84 0.36 07(02,21) 7.82 Virginia 21.94 0.31 19(07,26) 3.57Massachusetts 18.78 0.30 47(37,50) -11.36c Washington 20.07 0.32 38(24,44) -5.29Michigan 22.36 0.27 13(05,23) 5.55 West Virginia 22.10 0.60 17(03,32) 4.31Minnesota 18.80 0.34 46(36,50) -11.26c Wisconsin 20.51 0.34 27(21,41) -3.17Mississippi 23.91 0.53 03(02,14) 12.86c Wyoming 18.96 1.09 44(14,50) -10.53c

Missouri 22.55 0.35 11(03,23) 6.43

Table 4.23Cancer of the Female Breast (Invasive)

Age-Adjusted Cancer Deatha Rates By State, All Races, 2010-2014

Females

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a US 2014 cancer prevalence counts are based on 2014 cancer prevalence proportions from the SEER registries and 1/1/2014US population estimates based on the average of 2013 and 2014 population estimates from the US Bureau of the Census.Prevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 39/22 years.

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry.

e Maximum limited-duration prevalence: 39 years for 1975-2014 SEER 9 data; 22 years for 1992-2014 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders.

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groups.g h i (g) Cases diagnosed more than 39 years ago were estimated using the completeness index method (Capocaccia et. al. 1997,

Merrill et. al. 2000). (h) Complete prevalence is obtained by summing 0 to <39 and >=39. (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry.

- Statistic not shown. Statistic based on fewer than 5 cases estimated alive in SEER for the time interval.+ Not available.

WARNING: The Prevalence Estimates presented on this page utilize a different tumor selection criteria from previous CSR releases and areNOT directly comparable to estimates from previous CSR releases.Please see the Prevalence Comparison Chapter of this CSR for more information.

Years Since Diagnosis 0 to <5 5 to <10 10 to <15 15 to <20 20 to <25 25 to <30 0 to <22e 0 to <39e >=39g Completeh

Race Sex All Racesb Both Sexes 992,786 749,029 604,511 420,086 265,340 158,399 2,985,647 3,306,425 39,962 3,346,387

Males 8,065 4,445 2,975 1,591 771 502 17,763 18,729 106 18,835Females 984,721 744,584 601,536 418,495 264,569 157,897 2,967,884 3,287,696 39,856 3,327,552

Whiteb Both Sexes 829,791 643,093 531,954 372,775 237,980 143,539 2,573,918 2,864,694 35,145 2,899,839Males 6,559 3,898 2,422 1,447 676 433 14,931 15,791 0i 15,791Females 823,232 639,195 529,532 371,328 237,304 143,106 2,558,987 2,848,903 35,145 2,884,048

Blackb Both Sexes 106,559 68,983 47,290 31,019 18,227 10,061 269,070 289,503 + +Males 1,248 423 450 80 73 59 2,262 2,358 + +Females 105,311 68,560 46,840 30,939 18,154 10,002 266,808 287,145 3,155 290,300

Asian/ Both Sexes 42,168 28,907 20,281 12,642 + + 107,031 + + +Pacific Males 167 83 60 32 + + 364 + + +Islanderc Females 42,001 28,824 20,221 12,610 + + 106,667 + + +

Hispanicd Both Sexes 73,458 49,975 34,478 21,507 + + 184,655 + + +Males 368 194 107 53 + + 729 + + +Females 73,090 49,781 34,371 21,454 + + 183,926 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 0.8383% - 0.0001% 0.0068% 0.0888% 0.4916% 1.2849% 2.4279% 3.6738% 4.3313% 0.7694%

Males 0.0097% - - - 0.0004% 0.0028% 0.0093% 0.0277% 0.0621% 0.0914% 0.0103%Females 1.6462% - 0.0002% 0.0138% 0.1780% 0.9758% 2.5094% 4.5955% 6.6302% 6.8860% 1.4108%

Whitec Both Sexes 0.9225% - 0.0002% 0.0064% 0.0872% 0.4928% 1.3164% 2.5419% 3.9405% 4.6619% 0.8073%Males 0.0106% - - - 0.0003% 0.0027% 0.0085% 0.0282% 0.0663% 0.0970% 0.0107%Females 1.8313% - 0.0003% 0.0131% 0.1788% 1.0001% 2.6147% 4.8947% 7.1986% 7.4509% 1.4995%

Blackc Both Sexes 0.6111% - - 0.0077% 0.1014% 0.4950% 1.2072% 2.2223% 3.2020% 3.6165% 0.6997%Males 0.0100% - - - - 0.0053% 0.0185% 0.0399% 0.0755% 0.1023% 0.0139%Females 1.1591% - - 0.0153% 0.1901% 0.9240% 2.2462% 3.9300% 5.3791% 5.3578% 1.2064%

Asian/ Both Sexes 0.6354% - - 0.0077% 0.0865% 0.4888% 1.1880% 1.9307% 2.4704% 2.7376% 0.5983%Pacific Males 0.0047% - - - - - 0.0052% 0.0147% 0.0276% 0.0465% 0.0052%Islanderc Females 1.2146% - - 0.0155% 0.1647% 0.9200% 2.2072% 3.4993% 4.3764% 4.3912% 1.0722%

Hispanicd Both Sexes 0.3509% - - 0.0051% 0.0678% 0.3410% 0.9281% 1.7423% 2.4882% 2.7379% 0.5338%Males 0.0027% - - - - 0.0017% 0.0037% 0.0151% 0.0295% 0.0539% 0.0055%Females 0.7048% - - 0.0105% 0.1395% 0.6936% 1.8235% 3.2388% 4.3231% 4.3602% 0.9712%

Table 4.24Cancer of the Breast (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1, 2014By Race/Ethnicity, Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1, 2014, of the SEERc population diagnosed in the previous 22 yearsBy Age at Prevalence, Race/Ethnicity and Sex

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Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG).Percents may not sum to 100 due to rounding.

a Excludes Kaposi Sarcoma, mesothelioma, lymphomas, leukemias, myelomas, lymphoreticular, and immunoproliferative diseases.b Estimates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.c Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.d Epidermoid carcinoma includes squamous, basal, and transitional cell carcinomas.e Adenocarcinoma includes histologies 8050, 8140-8147, 8160-8162, 8180-8221, 8250-8507, 8514, 8520-8551, 8560, 8570-8574, 8576,

8940-8941.f Other adenocarcinomas include histologies 8141-8147, 8160-8162, 8180-8210, 8212-8221, 8250-8259, 8261-8479, 8483-8499,

8501-8502, 8505-8507, 8514, 8521, 8525-8529, 8531-8539, 8544-8551, 8560, 8570-8574, 8576, 8940-8941.g Other specific carcinomas include histologies 8012-8015, 8030-8046, 8150-8155, 8170-8175, 8230-8249, 8508, 8510-8513,

8561-8562, 8575, 8580-8671.h Other includes histologies 8012-8015, 8030-8046, 8150-8155, 8170-8175, 8230-8249, 8508, 8561-8562, 8575, 8580-8671.- Statistic not shown due to fewer than 16 cases during the time period.

Asian/Pacific American Indian/All Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 304,428 99.4% 241,361 99.5% 33,627 99.3% 25,184 99.3% 1,296 99.2% 33,042 99.2%Epidermoid carcinomad 153 0.1% 123 0.1% 21 0.1% - - - - - -(8051-8131)

Adenocarcinomae 298,577 97.5% 236,978 97.7% 32,637 96.3% 24,808 97.8% 1,268 97.1% 32,356 97.2%Adenocarcinoma, NOS (8140) 2,194 0.7% 1,709 0.7% 291 0.9% 150 0.6% - - 245 0.7%Infiltrating duct 225,092 73.5% 176,510 72.7% 25,569 75.5% 19,807 78.1% 1,010 77.3% 24,835 74.6%carcinoma (8500)Lobular carcinoma, NOS 28,594 9.3% 24,243 10.0% 2,498 7.4% 1,482 5.8% 103 7.9% 2,584 7.8%(8520)

Inflammatory 855 0.3% 679 0.3% 112 0.3% 53 0.2% - - 144 0.4%adenocarcinoma (8530)Infiltrating duct mixed 27,845 9.1% 22,988 9.5% 2,500 7.4% 2,012 7.9% 86 6.6% 3,140 9.4%and infiltrating lobularmixed (8522-8524)Mucinous adenocarcinoma 5,795 1.9% 4,427 1.8% 691 2.0% 605 2.4% 22 1.7% 580 1.7%(8480,8482)

Mucin-producing 64 0.0% 47 0.0% - - - - - - - -adenocarcinoma (8481)Tubular adenocarcinoma 1,660 0.5% 1,480 0.6% 94 0.3% 78 0.3% - - 135 0.4%(8211)

Papillary adenocarcinoma 1,923 0.6% 1,355 0.6% 316 0.9% 221 0.9% - - 197 0.6%(8050,8260,8503,8504)Paget disease (8540-8543) 1,080 0.4% 856 0.4% 108 0.3% 105 0.4% - - 122 0.4%Other adenocarcinomasf 3,475 1.1% 2,684 1.1% 447 1.3% 291 1.1% - - 365 1.1%

Other specific carcinomasg 2,484 0.8% 1,832 0.8% 454 1.3% 170 0.7% - - 331 1.0%Medullary adenocarcinoma 719 0.2% 489 0.2% 175 0.5% 49 0.2% - - 153 0.5%(8510-8513)

Otherh 1,765 0.6% 1,343 0.6% 279 0.8% 121 0.5% - - 178 0.5%Unspecified, Carcinoma, NOS 3,214 1.0% 2,428 1.0% 515 1.5% 198 0.8% 16 1.2% 342 1.0%(8010-8011,8020-8022)

Table 4.25

Cancer of the Female Breast (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases, 2010-2014Females by Race

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Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG).Percents may not sum to 100 due to rounding.

a Excludes Kaposi Sarcoma, mesothelioma, lymphomas, leukemias, myelomas, lymphoreticular, and immunoproliferative diseases.b Estimates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.c Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.d Other sarcomas include histologies 8680-8713, 8800-8921, 9040-9044, 9127-9136, 9150-9169, 9171-9252, 9370-9373, 9540-9582.e Other includes histologies 8720-8790, 8930-8936, 8950-9019, 9021-9030, 9060-9110, 9260-9365, 9380-9539.f Total includes carcinoma cases from the previous page.- Statistic not shown due to fewer than 16 cases during the time period.

Asian/Pacific American Indian/All Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Sarcoma and other soft tissue 334 0.1% 252 0.1% 52 0.2% 24 0.1% - - 38 0.1%tumors (8680-8713,8800-8921,9040-9044,9120-9136,9150-9252,9370-9373,9540-9582)

Hemangiosarcomas 169 0.1% 138 0.1% 18 0.1% - - - - - -(9120-9126,9170)

Other sarcomasd 165 0.1% 114 0.0% 34 0.1% - - - - 23 0.1%

Other specific types 728 0.2% 519 0.2% 91 0.3% 104 0.4% - - 130 0.4%(8720-8790,8930-8936,8950-9030,9060-9110,9260-9365,9380-9539)

Phyllodes tumor, malignant 620 0.2% 439 0.2% 70 0.2% 97 0.4% - - 111 0.3%(9020)

Othere 108 0.0% 80 0.0% 21 0.1% - - - - 19 0.1%

Unspecified (8000-8005) 708 0.2% 524 0.2% 105 0.3% 54 0.2% - - 94 0.3%

Totalf 306,198 100.0% 242,656 100.0% 33,875 100.0% 25,366 100.0% 1,306 100.0% 33,304 100.0%

Table 4.25 - continued

Cancer of the Female Breast (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases, 2010-2014Females by Race

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Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey andGeorgia excluding ATL/RG).Percents may not sum to 100 due to rounding.

a Excludes Kaposi Sarcoma, mesothelioma, lymphomas, leukemias, myelomas, lymphoreticular, and immunoproliferative diseases.b Estimates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.c Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.d Adenocarcinoma includes histologies 8050,8140-8147,8160-8162,8180-8221,8230,8250-8507,8514,8520-8551,8560,8570-8574,8576,8940-8941.e Ductal carcinoma includes histologies 8201, 8230, 8401, 8500-8507, 8523.f CIS = Carcinoma in situ.g Other adenocarcinomas include 8050, 8141-8147, 8160-8162, 8180-8200, 8202-8221, 8250-8400, 8402-8499, 8514, 8525-8551, 8560,

8570-8574, 8576, 8940-8941.h Other histologies include 8000-8049, 8051-8139, 8148-8159, 8163-8179, 8222-8229, 8231-8249, 8508-8513, 8515-8519, 8552-8559,

8561-8569, 8575, 8577-8939, 8942-9989.- Statistic not shown due to fewer than 16 cases during the time period.

Asian/Pacific American Indian/All Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Adenocarcinomad 76,695 99.9% 58,604 99.9% 8,733 99.9% 7,985 99.9% 290 100.0% 7,939 99.9%Adenocarcinoma in situ, NOS - - - - - - - - - - - -(8140/2)

Ductal carcinoma in situ e 65,234 85.0% 49,267 84.0% 7,664 87.6% 7,232 90.5% 253 87.2% 6,798 85.5%Cribiform carcinoma in situ 6,769 8.8% 5,030 8.6% 814 9.3% 816 10.2% 18 6.2% 696 8.8%(8201/2)

Ductal carcinoma in situ, 5,417 7.1% 4,226 7.2% 541 6.2% 578 7.2% 20 6.9% 481 6.1%solid type(8230/2)

Ductal carcinoma in situ, 21,448 27.9% 16,542 28.2% 2,436 27.9% 2,050 25.7% 97 33.4% 2,204 27.7%NOS (8500/2)

Comedocarcinoma in situ 6,419 8.4% 4,849 8.3% 706 8.1% 773 9.7% 35 12.1% 629 7.9%(8501/2)

Ductal carcinoma in situ 1,148 1.5% 780 1.3% 204 2.3% 141 1.8% - - 120 1.5%papillary(8503/2)

Noninfiltrating intracystic 249 0.3% 160 0.3% 36 0.4% 52 0.7% - - 29 0.4%carcinoma(8504/2)

Ductal carcinoma in situ 1,205 1.6% 950 1.6% 153 1.7% 86 1.1% - - 138 1.7%micropapillary(8507/2)

Intraductal with other types 22,396 29.2% 16,602 28.3% 2,764 31.6% 2,692 33.7% 76 26.2% 2,486 31.3%of carcinoma in situ(8523/2)

Lobular carcinoma in situ 8,904 11.6% 7,339 12.5% 783 9.0% 515 6.4% 32 11.0% 905 11.4%(8520/2-8521/2, 8524/2)Lobular carcinoma in situ, 8,886 11.6% 7,327 12.5% 778 8.9% 515 6.4% 31 10.7% 904 11.4%NOS (8520/2)

Lobular CISf with other CISf 18 0.0% - - - - - - - - - -(8524/2)

Intraductal and lobular 2,043 2.7% 1,626 2.8% 222 2.5% 169 2.1% - - 180 2.3%in situ carcinoma (8522/2)

Other adenocarcinomasg 506 0.7% 368 0.6% 63 0.7% 66 0.8% - - 56 0.7%

Other in situ histologiesh 85 0.1% 62 0.1% - - - - - - - -

Total 76,780 100.0% 58,666 100.0% 8,746 100.0% 7,990 100.0% 290 100.0% 7,948 100.0%

Table 4.26

Cancer of the Female Breast(In Situ)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases, 2010-2014Females by Race

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Delay-Adjusted IncidenceDelay-Adjusted Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence, SEER Delay Adjusted Incidence and US Death RatesCancer of the Female Breast, by Race

a

Figure 4.1

Source: SEER 9 areas and US Mortality Files (National Center for Health Statistics, CDC).Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute.The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.The APC is significantly different from zero (p < 0.05).

a

*

White BlackRate per 100,000 Rate per 100,000

Year of Diagnosis/Death Year of Diagnosis/Death

SEER Incidence APCsDelay Adj, 2004-14 = 0.2Observed, 2004-14 = 0.1

US Mortality APC1998-14 = -1.9*

SEER Incidence APCsDelay Adj, 1991-14 = 0.3*Observed, 1991-14 = 0.3*

US Mortality APC1993-14 = -1.5*

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Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence, SEER Delay Adjusted Incidence and US Death RatesCancer of the Female Breast, by Age and Race

a

Figure 4.2

Source: SEER 9 areas and US Mortality Files (National Center for Health Statistics, CDC).Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute.The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.The APC is significantly different from zero (p < 0.05).

a

*

White Ages <50 Black Ages <50 White Ages 50+ Black Ages 50+Rate per 100,000 Rate per 100,000 Rate per 100,000 Rate per 100,000

Year of Diagnosis/Death Year of Diagnosis/Death Year of Diagnosis/Death Year of Diagnosis/Death

SEER Incidence APCsDelay Adj, 1994-14 = 0.3*Observed, 1994-14 = 0.2*

US Mortality APC2004-14 = -1.7*

SEER Incidence APCsDelay Adj, 1991-14 = -0.2Observed, 1991-14 = -0.2

US Mortality APC1995-14 = -2.4*

SEER Incidence APCsDelay Adj, 2004-14 = 0.3Observed, 2004-14 = 0.2

US Mortality APC1998-14 = -1.8*

SEER Incidence APCsDelay Adj, 1988-14 = 0.6*Observed, 1992-14 = 0.4*

US Mortality APC1993-14 = -1.3*

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Observed IncidenceObserved Incidence

SEER Observed Incidence RatesCancer of the Female Breast (In Situ) , by Race

a

Figure 4.3

Source: SEER 9 areas.Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute.The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.The APC is significantly different from zero (p < 0.05).

a

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Year of Diagnosis Year of Diagnosis

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Joinpoint Analyses for Whites and Blacks from 1975-2014and for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics from 1992-2014

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White

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SEER Incidence and US Death RatesCancer of the Female Breast

Figure 4.4

Source: Incidence data for whites and blacks are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).Incidence data for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas, San Jose-Monterey,Los Angeles, Alaska Native Registry and Rural Georgia). Mortality data are from US Mortality Files, National Center for Health Statistics, CDC.Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines are calculated using the Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. Joinpoint analyses for Whites andBlacks during the 1975-2014 period allow a maximum of 5 joinpoints. Analyses for other ethnic groups during the period 1992-2014 allow a maximum of 4 joinpoints.API = Asian/Pacific Islander.AI/AN = American Indian/Alaska Native. Rates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry. Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma.

Incidence MortalityRate per 100,000 Rate per 100,000

Year of Diagnosis Year of Death

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Malig: Ages 50+

Figure 4.5

Cancer of Female Breast, Incidence Rates, 1975-2014In situ vs Malignant, by Age

All Races, FemalesIn Situ

Source: SEER 9 areas. Rates are per 100,000 and age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Rate per 100,000 (linear scale) Rate per 100,000 (log scale)

Year of Diagnosis Year of Diagnosis

In Situ:

In Situ:

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Malig: Ages 50+

Figure 4.6

Cancer of Female Breast, Incidence Rates, 1975-2014In situ vs Malignant, by Age

White, FemalesIn Situ

Source: SEER 9 areas. Rates are per 100,000 and age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Rate per 100,000 (linear scale) Rate per 100,000 (log scale)

Year of Diagnosis Year of Diagnosis

In Situ:

In Situ:

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Malig: Ages 50+

Figure 4.7

Cancer of Female Breast, Incidence Rates, 1975-2014In situ vs Malignant, by Age

Black, FemalesIn Situ

Source: SEER 9 areas. Rates are per 100,000 and age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Rate per 100,000 (linear scale) Rate per 100,000 (log scale)

Year of Diagnosis Year of Diagnosis

In Situ:

In Situ:

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Delay-Adjusted SEER Incidence, White

Delay-Adjusted SEER Incidence, Black

US Mortality, White

US Mortality, Black

Figure 4.8

Cancer of the Breast Delay-Adjusted SEER Incidence & US Mortality

White Females vs Black Females1975-2014

Source: SEER 9 areas and US Mortality Files (National Center for Health Statistics, CDC).Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines are calculated using the Joinpoint Regression Program Version 4.4, January 2017,National Cancer Institute.

Rate per 100,000

Year of Diagnosis/Death

Delay-Adjusted SEER Incidence

US Mortality

SEER Cancer Statistics Review 1975-2014 National Cancer Institute

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Lung & Bronchus, White

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Breast, White

Breast, Black

US Death Rates for Cancer of the Breast and Cancer of the Lung and BronchusWhite Females vs Black Females

1975-2014

Figure 4.9

Source: US Mortality Files, National Center for Health Statistics, CDC.Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103). Regression lines are calculated using the Joinpoint Regression Program Version 4.4, January 2017,National Cancer Institute.

Rate per 100,000

Year of Death

SEER Cancer Statistics Review 1975-2014 National Cancer Institute

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SEER 9 Delay-Adj. IncidenceSEER 9 Delay-Adj. Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj. IncidenceSEER 13 Delay-Adj. Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Female Breast, by Race

aFigure 4.10

Source: SEER 9 areas and SEER 13 areas.Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute.The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.The APC is significantly different from zero (p < 0.05).

a

*

All Races White BlackRate per 100,000 Rate per 100,000 Rate per 100,000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj, 2004-14 = 0.4*Observed, 2004-14 = 0.3

SEER 13 APCsDelay Adj, 2004-14 = 0.3Observed, 2004-14 = 0.2

SEER 9 APCsDelay Adj, 2004-14 = 0.2Observed, 2004-14 = 0.1

SEER 13 APCsDelay Adj, 2004-14 = 0.1Observed, 2004-14 = 0.0

SEER 9 APCsDelay Adj, 1991-14 = 0.3*Observed, 1991-14 = 0.3*

SEER 13 APCsDelay Adj, 1992-14 = 0.3*Observed, 1992-14 = 0.2*

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Figure 4.11

Cancer of the Female Breast5-Year SEER Conditional Relative Survival and

95% Confidence Intervals

Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta,San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA,Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG). California excluding SF/SJM/LA, Kentucky,Louisiana, New Jersey and Georgia excluding ATL/RG contribute cases for diagnosis years 2000 and later.The remaining 13 SEER Areas contribute cases for the entire time period.Percent surviving is not shown if based on less than 25 cases.Confidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error.

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Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0, 1, or 3 years

1998-2013 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2014 National Cancer Institute