SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16

SEER 9 Delay-Adjusted Incidencea 1975-2016

All Races 1975-82 25 1982-91 10 1991-07 -07 2007-16 -21 -21 -21

White 1975-82 26 1982-91 11 1991-07 -06 2007-16 -21 -21 -21

Black 1975-84 35 1984-03 -06 2003-16 -24 -24 -24

SEER 21 Delay-Adjusted Incidenceb 2000-2016

All Races 2000-08 -08 2008-16 -22 -21 -22

White 2000-08 -07 2008-16 -22 -20 -22

White NHef 2000-07 -04 2007-16 -19 -19 -19

Black 2000-09 -12 2009-16 -26 -23 -26

Black NHef 2000-09 -11 2009-16 -26 -23 -26

APIe 2000-16 -08 -08 -08

AIANeg 2000-16 -13 -13 -13

Hispanicf 2000-08 -07 2008-16 -22 -20 -22

US Cancer Mortalityc 1975-2016

All Races 1975-80 30 1980-90 18 1990-95 -02 1995-05 -10 2005-12 -23 2012-16 -37 -29 -37

White 1975-80 29 1980-90 18 1990-95 -01 1995-05 -08 2005-12 -22 2012-16 -36 -28 -36

Black 1975-81 35 1981-90 19 1990-95 -07 1995-04 -17 2004-13 -27 2013-16 -50 -35 -44

US Cancer Mortalityc 2000-2016

All Races 2000-05 -11 2005-10 -22 2010-14 -28 2014-16 -45 -30 -37

White 2000-05 -10 2005-10 -20 2010-14 -27 2014-16 -43 -29 -35

White NHef 2000-05 -08 2005-10 -19 2010-14 -26 2014-16 -42 -27 -34

Black 2000-04 -16 2004-13 -27 2013-16 -50 -35 -44

Black NHef 2000-04 -15 2004-13 -26 2013-16 -50 -34 -44

APIe 2000-11 -12 2011-16 -26 -19 -26

AIANeg 2000-16 -14 -14 -14

Hispanicf 2000-16 -23 -23 -23

Table 151

Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints

Both Sexes by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16

SEER 9 Delay-Adjusted Incidencea 1975-2016

All Races 1975-82 15 1982-91 -05 1991-08 -17 2008-16 -28 -27 -28

White 1975-81 14 1981-89 -01 1989-07 -16 2007-16 -27 -27 -27

Black 1975-84 29 1984-98 -14 1998-16 -29 -29 -29

SEER 21 Delay-Adjusted Incidenceb 2000-2016

All Races 2000-08 -17 2008-16 -29 -28 -29

White 2000-08 -16 2008-16 -29 -28 -29

White NHef 2000-08 -15 2008-16 -27 -25 -27

Black 2000-16 -27 -27 -27

Black NHef 2000-16 -27 -27 -27

APIe 2000-16 -15 -15 -15

AIANeg 2000-16 -18 -18 -18

Hispanicf 2000-07 -14 2007-16 -32 -32 -32

US Cancer Mortalityc 1975-2016

All Races 1975-78 24 1978-84 12 1984-91 03 1991-05 -19 2005-12 -29 2012-16 -43 -35 -43

White 1975-80 19 1980-87 07 1987-91 01 1991-05 -17 2005-12 -29 2012-16 -42 -34 -42

Black 1975-82 29 1982-90 13 1990-94 -13 1994-03 -27 2003-13 -34 2013-16 -56 -41 -51

US Cancer Mortalityc 2000-2016

All Races 2000-05 -20 2005-10 -28 2010-14 -34 2014-16 -50 -36 -42

White 2000-05 -19 2005-10 -27 2010-14 -34 2014-16 -49 -35 -41

White NHef 2000-05 -17 2005-10 -26 2010-14 -33 2014-16 -47 -34 -40

Black 2000-13 -33 2013-16 -58 -41 -52

Black NHef 2000-13 -32 2013-16 -58 -41 -51

APIe 2000-08 -13 2008-16 -28 -27 -28

AIANeg 2000-16 -16 -16 -16

Hispanicf 2000-16 -31 -31 -31

Table 152

Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16

SEER 9 Delay-Adjusted Incidencea 1975-2016

All Races 1975-82 56 1982-91 34 1991-06 05 2006-16 -15 -15 -15

White 1975-88 48 1988-97 14 1997-07 02 2007-16 -15 -15 -15

Black 1975-90 42 1990-06 06 2006-16 -19 -19 -19

SEER 21 Delay-Adjusted Incidenceb 2000-2016

All Races 2000-07 03 2007-16 -15 -15 -15

White 2000-07 04 2007-16 -15 -15 -15

White NHef 2000-07 06 2007-16 -13 -13 -13

Black 2000-09 03 2009-16 -20 -15 -20

Black NHef 2000-09 04 2009-16 -20 -15 -20

APIe 2000-16 01 01 01

AIANeg 2000-16 -07 -07 -07

Hispanicf 2000-16 -04 -04 -04

US Cancer Mortalityc 1975-2016

All Races 1975-83 59 1983-92 38 1992-02 05 2002-07 -07 2007-14 -20 2014-16 -42 -25 -31

White 1975-83 59 1983-92 38 1992-02 06 2002-07 -06 2007-14 -19 2014-16 -40 -24 -29

Black 1975-82 63 1982-92 37 1992-04 04 2004-13 -19 2013-16 -45 -27 -38

US Cancer Mortalityc 2000-2016

All Races 2000-02 06 2002-07 -07 2007-14 -20 2014-16 -42 -25 -31

White 2000-02 06 2002-07 -06 2007-14 -19 2014-16 -40 -24 -29

White NHef 2000-02 07 2002-07 -04 2007-14 -18 2014-16 -39 -22 -28

Black 2000-04 06 2004-13 -19 2013-16 -45 -27 -38

Black NHef 2000-05 05 2005-08 -28 2008-13 -14 2013-16 -47 -27 -39

APIe 2000-13 -03 2013-16 -33 -13 -26

AIANeg 2000-02 108 2002-16 -17 -17 -17

Hispanicf 2000-16 -11 -11 -11

Table 153

Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046 8050-8052

8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-8241 8243-82468249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 8550 8560 85628570-8572 8574-8576

c Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2012-16

SEER 9 Observed Incidencec for Small Cell Cancer of the Lung and Bronchusa 1975-2016

All Races Both Sexes 1975-82 62 1982-89 11 1989-07 -23 2007-16 -31 -31

All Races Male 1975-81 56 1981-88 00 1988-16 -31 -31

All Races Female 1975-82 97 1982-91 29 1991-07 -16 2007-16 -29 -29

White Both Sexes 1975-82 64 1982-89 13 1989-07 -21 2007-16 -31 -31

White Male 1975-78 88 1978-86 20 1986-16 -30 -30

White Female 1975-82 100 1982-90 34 1990-07 -13 2007-16 -29 -29

Black Both Sexes 1975-86 49 1986-16 -25 -25

Black Male 1975-85 50 1985-16 -34 -34

Black Female 1975-91 45 1991-16 -19 -19

SEER 9 Observed Incidencec for Non-Small Cell Cancer of the Lung and Bronchusb 1975-2016

All Races Both Sexes 1975-80 52 1980-88 17 1988-00 -09 2000-03 62 2003-16 -17 -17

All Races Male 1975-80 44 1980-87 06 1987-00 -20 2000-03 51 2003-16 -25 -25

All Races Female 1975-78 102 1978-88 47 1988-99 06 1999-05 38 2005-16 -13 -13

White Both Sexes 1975-79 61 1979-88 19 1988-00 -08 2000-03 61 2003-16 -17 -17

White Male 1975-80 44 1980-88 05 1988-99 -23 1999-02 54 2002-16 -23 -23

White Female 1975-78 104 1978-88 49 1988-00 07 2000-03 71 2003-16 -09 -09

Black Both Sexes 1975-84 45 1984-00 -12 2000-03 58 2003-16 -24 -24

Black Male 1975-84 39 1984-00 -22 2000-03 43 2003-16 -32 -32

Black Female 1975-90 50 1990-97 -15 1997-05 41 2005-16 -19 -19

Table 154

Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

Trends in SEER 9 Observed Incidencec Using the Joinpoint Regression Program

1975-2016 With up to Five Joinpoints

By Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 5622 9432 2833 5560 9359 2839 7201 12585 30721980 6065 9996 3221 5942 9769 3236 8662 15143 38251981 6203 9941 3511 6153 9844 3552 8231 14296 37451982 6329 10069 3673 6305 9968 3768 8037 14106 35681983 6345 9946 3788 6303 9763 3909 8662 15134 39491984 6549 10205 3945 6433 9989 3961 9293 15884 44821985 6461 9859 4025 6397 9684 4087 8956 14968 46041986 6577 9903 4229 6514 9732 4294 9294 15627 48671987 6790 10151 4416 6808 10066 4549 8476 14359 43281988 6806 9870 4634 6826 9792 4773 8824 14493 48261989 6756 9796 4612 6757 9706 4726 8904 14277 51371990 6808 9691 4779 6823 9611 4896 8678 13717 52131991 6919 9720 4958 6896 9588 5063 9313 14476 57031992 6946 9720 4985 6892 9489 5104 9399 14873 56061993 6775 9395 4915 6780 9251 5063 8636 13535 52541994 6717 9093 5054 6728 9013 5161 8716 13139 56531995 6685 8982 5043 6709 8795 5243 8587 13894 50121996 6646 8796 5124 6678 8666 5297 8457 12835 55731997 6662 8631 5259 6719 8480 5493 8227 12954 50491998 6755 8802 5298 6800 8660 5502 8752 13087 58301999 6583 8457 5250 6628 8325 5442 8456 12246 58852000 6414 8211 5122 6465 8078 5321 8071 11509 57812001 6415 8141 5165 6504 8107 5348 8063 11451 57822002 6406 8043 5250 6479 7984 5423 8148 11310 60712003 6476 8105 5309 6551 7956 5565 8120 11956 55732004 6224 7628 5207 6279 7530 5377 7616 10527 57022005 6303 7582 5385 6401 7553 5580 7469 9797 59492006 6230 7429 5345 6282 7308 5535 7675 10110 59962007 6209 7375 5358 6312 7286 5605 7413 10068 56552008 6041 7220 5186 6115 7078 5429 7503 10342 56122009 6005 7074 5232 6073 6979 5417 7437 9820 58672010 5781 6808 5018 5890 6787 5219 6723 8582 55002011 5635 6578 4944 5736 6542 5145 6592 8652 52562012 5537 6414 4884 5580 6304 5044 6969 8937 56402013 5422 6186 4855 5491 6091 5049 6377 8182 51712014 5337 6041 4817 5475 6046 5061 6049 7519 50822015 5202 5901 4677 5294 5832 4891 6027 7634 49752016 5126 5822 4599 5207 5735 4811 5895 7498 4764

Table 155Cancer of the Lung and Bronchus (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2016 6158 8234 4628 6197 8179 4747 7665 11370 50891975-1979 5622 9432 2833 5560 9359 2839 7201 12585 30721980 6065 9996 3221 5942 9769 3236 8662 15143 38251981 6203 9941 3511 6153 9844 3552 8231 14296 37451982 6329 10069 3673 6305 9968 3768 8037 14106 35681983 6345 9946 3788 6303 9763 3909 8662 15134 39491984 6549 10205 3945 6433 9989 3961 9293 15884 44821985 6461 9859 4025 6397 9684 4087 8956 14968 46041986 6577 9903 4229 6514 9732 4294 9294 15627 48671987 6790 10151 4416 6808 10066 4549 8476 14359 43281988 6806 9870 4634 6826 9792 4773 8824 14493 48261989 6756 9796 4612 6757 9706 4726 8904 14277 51371990 6808 9691 4779 6823 9611 4896 8678 13717 52131991 6919 9720 4958 6896 9588 5063 9313 14476 57031992 6946 9720 4985 6892 9489 5104 9399 14873 56061993 6775 9395 4915 6780 9251 5063 8636 13535 52541994 6717 9093 5054 6728 9013 5161 8716 13139 56531995 6685 8982 5043 6709 8795 5243 8587 13894 50121996 6646 8796 5124 6678 8666 5297 8457 12835 55731997 6662 8631 5259 6719 8480 5493 8227 12954 50491998 6755 8802 5298 6800 8660 5502 8752 13087 58301999 6583 8457 5250 6628 8325 5442 8456 12246 58852000 6414 8211 5122 6465 8078 5321 8071 11509 57812001 6415 8141 5165 6504 8107 5348 8063 11451 57822002 6406 8043 5250 6479 7984 5423 8148 11310 60712003 6476 8105 5309 6551 7956 5565 8120 11956 55732004 6224 7628 5207 6279 7530 5377 7616 10527 57022005 6303 7582 5385 6401 7553 5580 7469 9797 59492006 6230 7429 5345 6282 7308 5535 7675 10110 59962007 6209 7375 5358 6312 7286 5605 7413 10068 56552008 6037 7215 5183 6112 7074 5426 7496 10332 56062009 5998 7066 5226 6066 6971 5411 7422 9801 58552010 5771 6797 5010 5881 6776 5211 6703 8557 54842011 5622 6562 4932 5723 6528 5134 6567 8618 52362012 5520 6395 4870 5565 6287 5030 6933 8890 56122013 5402 6164 4838 5473 6071 5033 6340 8136 51402014 5308 6007 4791 5445 6013 5034 5997 7452 50382015 5158 5850 4638 5250 5783 4851 5954 7541 49152016 5024 5704 4510 5098 5613 4713 5741 7301 4641

Table 156Cancer of the Lung and Bronchus (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Note Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2016 845 1053 689 897 1097 746 798 1082 5981975-1979 777 1214 447 797 1249 461 757 1177 4351980 911 1420 525 934 1440 556 999 1753 4381981 974 1459 613 1003 1487 648 928 1587 4341982 1044 1500 717 1081 1536 762 969 1608 4921983 1039 1492 710 1078 1509 766 923 1520 4951984 1071 1524 741 1107 1571 776 1041 1499 6861985 1047 1498 710 1080 1526 752 1112 1790 6271986 1122 1557 798 1157 1605 827 1226 1770 8351987 1067 1415 822 1118 1457 886 968 1461 6201988 1138 1528 853 1191 1562 923 1049 1786 5301989 1126 1486 870 1171 1525 923 1207 1767 8351990 1067 1386 840 1128 1449 906 935 1370 6211991 1131 1399 939 1171 1432 988 1234 1592 10001992 1051 1341 845 1097 1385 896 1022 1332 8051993 1003 1234 834 1048 1264 894 943 1336 6741994 977 1169 842 1024 1197 905 995 1353 7501995 987 1230 812 1037 1264 873 950 1389 6611996 972 1209 798 1028 1248 864 880 1202 6841997 953 1086 864 1011 1112 948 786 1082 6051998 929 1086 814 986 1128 882 950 1226 7551999 882 1006 797 933 1025 878 825 1121 6052000 880 1045 759 928 1085 813 959 1180 8022001 837 986 733 891 1035 793 857 1091 6892002 829 939 754 898 986 839 721 980 5712003 822 912 760 873 938 833 793 950 6832004 812 900 749 852 925 800 864 1008 7752005 759 869 682 822 924 751 663 778 5882006 769 853 708 825 884 786 683 819 5892007 768 860 702 833 896 792 710 940 5442008 709 796 646 758 811 720 638 885 4872009 713 778 669 760 810 727 751 836 6942010 681 749 634 746 798 713 589 688 5152011 627 685 586 677 709 657 528 644 4492012 646 719 589 694 755 646 664 831 5622013 635 713 579 689 749 648 545 677 4662014 602 636 580 655 663 656 584 657 5292015 592 625 570 641 654 638 577 628 5382016 548 605 506 578 612 556 567 632 511

Table 157Small Cell Cancer of the Lung and Bronchus (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Note Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 80468050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2016 4232 5650 3168 4209 5550 3209 5524 8192 36411975-1979 3457 5732 1736 3374 5599 1726 4845 8622 19141980 3934 6432 2069 3813 6216 2054 5912 10314 25801981 4054 6479 2259 4000 6385 2268 5497 9467 24971982 4141 6626 2320 4081 6502 2349 5581 9781 24131983 4184 6620 2406 4116 6437 2468 6076 10714 26021984 4346 6800 2550 4207 6555 2526 6733 11665 30981985 4309 6584 2635 4224 6387 2658 6360 10717 31771986 4312 6455 2746 4234 6264 2782 6472 10968 32571987 4563 6947 2835 4527 6819 2888 6052 10401 29581988 4512 6580 3002 4501 6507 3065 5991 9694 33341989 4426 6440 2972 4387 6333 3012 6100 9784 34691990 4474 6359 3109 4442 6264 3139 5987 9231 37151991 4492 6376 3137 4414 6190 3168 6484 10215 38091992 4524 6385 3170 4439 6144 3228 6481 10487 36511993 4365 6101 3096 4348 5980 3170 5677 8994 33691994 4303 5855 3184 4269 5733 3235 5855 9039 35941995 4240 5707 3168 4219 5556 3259 5829 9315 34321996 4152 5446 3210 4145 5339 3292 5417 8130 35441997 4136 5453 3160 4149 5338 3277 5359 8462 32391998 4211 5541 3249 4235 5444 3376 5484 8292 35781999 4049 5260 3160 4051 5157 3245 5431 7949 37092000 3858 4969 3049 3876 4889 3152 4896 6938 34982001 4674 6000 3693 4707 5935 3796 6015 8662 42502002 4692 5921 3800 4689 5828 3866 6245 8595 46532003 4737 6004 3809 4760 5854 3972 6164 9240 40772004 4561 5651 3761 4566 5523 3865 5634 7961 40832005 4680 5621 3990 4690 5536 4074 5808 7500 46662006 4644 5584 3943 4619 5417 4029 6067 8189 45952007 4637 5534 3968 4649 5397 4093 5873 7968 44672008 4565 5465 3906 4563 5295 4039 5942 8128 44502009 4495 5297 3906 4521 5201 4020 5636 7521 43792010 4373 5180 3767 4421 5145 3871 5097 6437 42112011 4289 4998 3757 4311 4915 3857 5272 6992 41432012 4171 4839 3672 4155 4711 3744 5422 6911 43882013 4089 4646 3672 4098 4528 3780 4955 6390 39932014 4020 4519 3650 4081 4477 3791 4659 5822 39062015 3890 4428 3480 3905 4333 3579 4717 6046 38302016 3861 4340 3496 3889 4240 3624 4498 5736 3623

Table 158Non-Small Cell Cancer of the Lung and Bronchus (Invasive)Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2016 5136 7361 3507 5150 7292 3577 5815 9343 34121975-1979 4541 8014 2010 4485 7897 2021 5341 9819 19781980 4941 8471 2413 4875 8327 2422 5916 10667 24571981 4999 8516 2495 4928 8352 2510 6057 10971 25101982 5143 8679 2647 5078 8518 2672 6227 11255 26301983 5240 8704 2810 5170 8540 2828 6368 11276 28731984 5336 8822 2894 5264 8624 2927 6507 11798 27981985 5432 8854 3041 5368 8669 3081 6576 11750 29641986 5504 8895 3141 5436 8703 3176 6695 11918 31001987 5624 9005 3272 5556 8809 3304 6865 12177 32481988 5697 8987 3414 5635 8786 3457 6918 12215 33541989 5790 8977 3577 5721 8757 3627 7104 12472 34871990 5885 9056 3685 5818 8840 3731 7206 12517 36481991 5899 8988 3761 5838 8776 3812 7164 12358 37161992 5890 8801 3870 5834 8598 3921 7135 12106 38551993 5913 8760 3928 5866 8552 3997 7112 12198 37721994 5854 8569 3962 5815 8378 4030 7015 11863 38611995 5838 8437 4026 5808 8262 4097 6928 11608 38841996 5791 8282 4041 5769 8115 4122 6830 11318 39081997 5751 8133 4082 5731 7983 4152 6789 11021 40531998 5708 7989 4098 5693 7847 4169 6686 10740 40671999 5542 7697 4015 5531 7567 4086 6500 10361 40002000 5585 7648 4112 5599 7541 4208 6377 10087 39642001 5532 7532 4101 5555 7434 4205 6254 9932 38802002 5500 7367 4160 5531 7289 4264 6205 9559 40212003 5419 7203 4129 5452 7132 4230 6092 9296 40252004 5337 7043 4096 5371 6974 4199 5979 9041 39952005 5285 6949 4071 5332 6909 4170 5852 8696 40122006 5173 6739 4026 5227 6705 4136 5673 8389 39062007 5071 6517 4010 5128 6476 4130 5538 8219 38132008 4959 6373 3913 5028 6351 4040 5313 7820 36882009 4841 6154 3863 4918 6141 3997 5156 7549 35902010 4742 6005 3794 4811 5992 3917 5114 7352 36272011 4600 5787 3701 4672 5785 3820 4931 7002 35442012 4494 5621 3642 4565 5612 3764 4834 6886 34732013 4344 5395 3546 4414 5392 3664 4696 6600 34112014 4220 5195 3472 4300 5205 3599 4471 6249 32782015 4063 4977 3356 4151 4991 3494 4219 5902 30742016 3847 4692 3191 3929 4709 3318 4019 5535 2978

Table 159Cancer of the Lung and Bronchus (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2012-2016All ages 549 630 489 567 635 518 562 735 446Under 65 164 173 156 165 169 161 205 245 17265 and over 3209 3788 2792 3349 3856 2984 3028 4121 2340

All ages (WHO world std)c 385 435 346 397 436 366 408 526 325

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 01 - - 01 - - - - -5-9 - - - - - - - - -10-14 01 - - 01 - - - - -15-19 01 01 01 01 01 02 - - -20-24 03 03 03 03 03 03 04 05 -25-29 06 06 06 06 05 06 05 06 -30-34 12 11 12 10 09 12 16 20 1335-39 27 26 27 26 24 27 30 35 2540-44 66 60 71 65 58 72 66 71 6245-49 178 169 187 179 167 192 212 212 21250-54 442 439 444 444 429 458 566 620 51955-59 850 903 799 855 882 830 1107 1324 92160-64 1349 1525 1188 1365 1494 1244 1677 2190 126365-69 2201 2482 1952 2280 2495 2085 2356 3095 179670-74 3236 3637 2901 3400 3703 3140 3154 4229 239775-79 3951 4586 3459 4151 4693 3720 3631 4893 282080-84 4083 4983 3462 4257 5096 3664 3549 4899 280385+ 3082 4222 2492 3169 4290 2585 2606 3925 2057

US MortalityAge at DeathAge-Adjusted Rates 2012-2016All ages 419 516 344 427 517 356 443 621 324Under 65 115 133 98 116 131 101 143 185 10765 and over 2516 3164 2040 2575 3186 2120 2523 3633 1822

All ages (WHO world std)c 246 298 203 250 297 210 273 376 197

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 00 - - - - - - - -15-19 00 00 - 00 - - - - -20-24 01 01 01 01 01 01 01 - -25-29 02 02 01 02 02 01 02 02 -30-34 05 05 04 04 04 04 07 10 0435-39 13 14 12 12 13 12 16 22 1140-44 40 40 39 41 40 41 42 49 3745-49 120 125 115 123 125 120 130 154 10950-54 316 347 286 317 341 293 399 482 32655-59 617 722 518 617 706 531 789 1022 58960-64 966 1181 769 972 1161 795 1197 1658 82265-69 1540 1865 1250 1567 1853 1304 1749 2468 119070-74 2337 2831 1916 2397 2849 2003 2462 3475 173275-79 2989 3657 2459 3072 3694 2568 2934 4139 214680-84 3433 4380 2766 3519 4432 2861 3203 4678 237985+ 3155 4456 2479 3212 4501 2532 2859 4443 2200

Table 1510Cancer of the Lung and Bronchus (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046

8050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576

c SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Small Cell Cancer of the Lung and Bronchusa Age at DiagnosisAge-Adjusted Rates 2012-2016All ages 61 66 58 67 70 65 49 58 43Under 65 22 22 22 24 24 25 19 21 1865 and over 332 372 305 363 393 342 254 310 218

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 01 - - - - - - - -35-39 01 02 01 02 02 01 - - -40-44 06 06 06 07 06 07 05 - -45-49 22 21 23 25 24 27 18 18 1750-54 59 57 61 68 63 72 48 54 4355-59 122 120 124 135 129 141 107 111 10360-64 187 195 180 205 208 203 172 193 15565-69 290 312 270 319 330 309 230 295 18170-74 384 401 369 424 429 419 280 330 24575-79 415 458 382 453 486 427 330 393 28980-84 340 402 297 365 420 326 243 265 23185+ 170 259 124 178 265 132 139 210 109

Non-Small Cell Cancer Lung and Bronchusb Age at DiagnosisAge-Adjusted Rates 2012-2016All ages 417 477 371 426 476 389 442 577 351Under 65 131 137 125 129 132 127 171 202 14465 and over 2391 2829 2072 2476 2860 2195 2320 3169 1778

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 00 - - - - - - - -15-19 01 01 01 01 - 02 - - -20-24 03 02 03 02 02 03 04 05 -25-29 05 05 06 05 05 06 04 - -30-34 10 09 11 09 07 10 13 15 1135-39 23 22 25 23 21 24 26 29 2340-44 56 50 62 55 48 62 55 59 5245-49 147 137 156 144 132 157 183 185 18150-54 355 349 361 349 333 365 480 519 44555-59 673 713 635 664 685 645 923 1091 77960-64 1059 1193 937 1056 1152 965 1362 1775 102965-69 1731 1945 1543 1773 1935 1626 1930 2527 147770-74 2531 2847 2266 2636 2877 2428 2536 3387 193875-79 3045 3563 2642 3172 3615 2820 2860 3948 216080-84 2969 3659 2491 3076 3729 2613 2618 3638 205585+ 1761 2516 1371 1798 2552 1406 1460 2245 1133

Table 1511Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

SEER Incidencec Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016

d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 155 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 106 1511999-2001b 153 131 179 155 134 180 127 108 1542002-2004b 161 142 184 165 144 189 133 128 1392005-2008b 181 156 208 185 160 212 147 125 1722009-2015b 206f 172f 243f 207f 173f 242f 193f 158f 230f

5-Year Period Survival (Percent)cd

2015 202 167 238 203 169 238 178 144 218

Stage Distribution () 2009-2015ce

All StagesNumber of cases 263385 137877 125508 212884 110083 102801 30661 16749 13912Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 14 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 56 58 54 61 64 58UnstagedUnknown 4 4 5 5 4 5 3 3 3

5-Year Relative Survival (Percent) 2009-2015c

Age at DiagnosisAges lt45 346 295 393 362 308 412 274 239 316Ages 45-54 221 175 271 225 177 276 195 151 243Ages 55-64 208 171 255 209 173 254 181 146 234Ages 65-74 210 174 252 213 177 253 175 143 215Ages 75+ 149 124 173 152 126 175 123 93 148Ages lt65 218 178 267 220 179 268 190 152 241Ages 65+ 181 151 211 183 153 212 153 124 184

StageeAll Stages 194 161 230 195 162 230 171 139 210Localized 574 512 627 573 515 622 538 446 621Regional 308 271 348 307 270 346 289 258 322Distant 52 42 63 49 40 61 52 43 63UnstagedUnknown 82 75 90 74 65 83 95 83 108

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046

8050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576

c SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Small Cell Cancer of the Lung and Bronchusa Age at DiagnosisAge-Adjusted Rates 2012-2016All ages 61 66 58 67 70 65 49 58 43Under 65 22 22 22 24 24 25 19 21 1865 and over 332 372 305 363 393 342 254 310 218

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 01 - - - - - - - -35-39 01 02 01 02 02 01 - - -40-44 06 06 06 07 06 07 05 - -45-49 22 21 23 25 24 27 18 18 1750-54 59 57 61 68 63 72 48 54 4355-59 122 120 124 135 129 141 107 111 10360-64 187 195 180 205 208 203 172 193 15565-69 290 312 270 319 330 309 230 295 18170-74 384 401 369 424 429 419 280 330 24575-79 415 458 382 453 486 427 330 393 28980-84 340 402 297 365 420 326 243 265 23185+ 170 259 124 178 265 132 139 210 109

Non-Small Cell Cancer Lung and Bronchusb Age at DiagnosisAge-Adjusted Rates 2012-2016All ages 417 477 371 426 476 389 442 577 351Under 65 131 137 125 129 132 127 171 202 14465 and over 2391 2829 2072 2476 2860 2195 2320 3169 1778

Age-Specific Rates 2012-2016lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 00 - - - - - - - -15-19 01 01 01 01 - 02 - - -20-24 03 02 03 02 02 03 04 05 -25-29 05 05 06 05 05 06 04 - -30-34 10 09 11 09 07 10 13 15 1135-39 23 22 25 23 21 24 26 29 2340-44 56 50 62 55 48 62 55 59 5245-49 147 137 156 144 132 157 183 185 18150-54 355 349 361 349 333 365 480 519 44555-59 673 713 635 664 685 645 923 1091 77960-64 1059 1193 937 1056 1152 965 1362 1775 102965-69 1731 1945 1543 1773 1935 1626 1930 2527 147770-74 2531 2847 2266 2636 2877 2428 2536 3387 193875-79 3045 3563 2642 3172 3615 2820 2860 3948 216080-84 2969 3659 2491 3076 3729 2613 2618 3638 205585+ 1761 2516 1371 1798 2552 1406 1460 2245 1133

Table 1511Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

SEER Incidencec Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016

d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 155 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 106 1511999-2001b 153 131 179 155 134 180 127 108 1542002-2004b 161 142 184 165 144 189 133 128 1392005-2008b 181 156 208 185 160 212 147 125 1722009-2015b 206f 172f 243f 207f 173f 242f 193f 158f 230f

5-Year Period Survival (Percent)cd

2015 202 167 238 203 169 238 178 144 218

Stage Distribution () 2009-2015ce

All StagesNumber of cases 263385 137877 125508 212884 110083 102801 30661 16749 13912Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 14 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 56 58 54 61 64 58UnstagedUnknown 4 4 5 5 4 5 3 3 3

5-Year Relative Survival (Percent) 2009-2015c

Age at DiagnosisAges lt45 346 295 393 362 308 412 274 239 316Ages 45-54 221 175 271 225 177 276 195 151 243Ages 55-64 208 171 255 209 173 254 181 146 234Ages 65-74 210 174 252 213 177 253 175 143 215Ages 75+ 149 124 173 152 126 175 123 93 148Ages lt65 218 178 267 220 179 268 190 152 241Ages 65+ 181 151 211 183 153 212 153 124 184

StageeAll Stages 194 161 230 195 162 230 171 139 210Localized 574 512 627 573 515 622 538 446 621Regional 308 271 348 307 270 346 289 258 322Distant 52 42 63 49 40 61 52 43 63UnstagedUnknown 82 75 90 74 65 83 95 83 108

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016

d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 155 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 106 1511999-2001b 153 131 179 155 134 180 127 108 1542002-2004b 161 142 184 165 144 189 133 128 1392005-2008b 181 156 208 185 160 212 147 125 1722009-2015b 206f 172f 243f 207f 173f 242f 193f 158f 230f

5-Year Period Survival (Percent)cd

2015 202 167 238 203 169 238 178 144 218

Stage Distribution () 2009-2015ce

All StagesNumber of cases 263385 137877 125508 212884 110083 102801 30661 16749 13912Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 14 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 56 58 54 61 64 58UnstagedUnknown 4 4 5 5 4 5 3 3 3

5-Year Relative Survival (Percent) 2009-2015c

Age at DiagnosisAges lt45 346 295 393 362 308 412 274 239 316Ages 45-54 221 175 271 225 177 276 195 151 243Ages 55-64 208 171 255 209 173 254 181 146 234Ages 65-74 210 174 252 213 177 253 175 143 215Ages 75+ 149 124 173 152 126 175 123 93 148Ages lt65 218 178 267 220 179 268 190 152 241Ages 65+ 181 151 211 183 153 212 153 124 184

StageeAll Stages 194 161 230 195 162 230 171 139 210Localized 574 512 627 573 515 622 538 446 621Regional 308 271 348 307 270 346 289 258 322Distant 52 42 63 49 40 61 52 43 63UnstagedUnknown 82 75 90 74 65 83 95 83 108

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Note Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesb SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016

c Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundinge The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 36 31 48 37 31 49 37 38 361978-1980a 42 32 65 43 33 64 31 24 501981-1983a 45 35 62 46 36 61 53 41 821984-1986a 45 35 62 47 36 64 35 22 561987-1989a 51 39 66 51 39 68 40 33 511990-1992a 54 45 64 54 45 65 42 39 441993-1995a 64 51 79 63 50 76 67 40 1041996-1998a 58 52 65 60 54 66 36 26 451999-2001a 58 48 68 56 44 69 52 60 422002-2004a 65 47 82 65 44 84 53 53 512005-2008a 69 54 85 68 53 84 74 56 942009-2015a 66e 51e 82e 66e 49e 82e 63e 52e 70

5-Year Period Survival (Percent)bc

2015 65 49 81 65 48 80 72 58 86

Stage Distribution () 2009-2015bd

All StagesNumber of cases 33824 16941 16883 29208 14394 14814 3123 1591 1532Percent 100 100 100 100 100 100 100 100 100Localized 4 4 4 4 4 4 4 4 3Regional 19 17 21 19 17 21 19 17 21Distant 75 77 73 75 77 73 75 77 74UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2009-2015b

Age at DiagnosisAges lt45 134 113 158 135 117 155 111 62f -Ages 45-54 90 61 118 89 56 119 111 97 126Ages 55-64 77 55 99 76 53 99 78 54 101Ages 65-74 60 49 71 60 47 72 58 59 56Ages 75+ 36 25 45 36 24 47 36 33 38Ages lt65 82 58 106 81 55 106 89 68 110Ages 65+ 50 40 60 50 38 62 50 51 49

StagedAll Stages 63 47 79 63 45 79 70 60 80Localized 273 236 306 272 227 310 320f 342f 301f

Regional 156 130 177 158 131 180 154 124 177Distant 28 20 37 27 19 36 37 32 42UnstagedUnknown 95 54 131 91 31 140 46 85f -

Table 1513Small Cell Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Note Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046 8050-80528070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-8241 8243-82468249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 8550 8560 85628570-8572 8574-8576

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016

c Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundinge The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 164 148 211 168 150 215 134 124 1771978-1980a 167 148 214 170 152 215 142 116 2281981-1983a 171 150 217 175 154 221 139 122 1921984-1986a 166 144 210 170 147 215 131 119 1641987-1989a 169 152 198 173 155 205 132 129 1391990-1992a 177 155 211 183 162 217 128 111 1621993-1995a 187 161 225 193 165 232 151 133 1851996-1998a 194 167 229 199 171 235 153 127 1951999-2001a 200 169 241 207 176 246 148 120 1892002-2004a 196 170 228 204 176 237 150 139 1652005-2008a 218 187 254 228 195 264 163 137 1932009-2015a 251e 208e 297e 255e 213e 301e 223e 180e 270e

5-Year Period Survival (Percent)bc2015 246 203 293 251 207 297 203 163 251

Stage Distribution () 2009-2015bdAll StagesNumber of cases 198888 105279 93609 158136 82886 75250 24379 13412 10967Percent 100 100 100 100 100 100 100 100 100Localized 19 17 22 20 18 23 15 13 18Regional 24 24 23 24 25 24 24 23 24Distant 55 57 52 54 56 51 60 62 56UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2009-2015bAge at DiagnosisAges lt45 367 314 415 390 329 443 289 257 325Ages 45-54 248 196 303 257 203 315 209 160 261Ages 55-64 243 200 299 248 205 302 201 162 258Ages 65-74 253 209 304 259 215 308 203 163 252Ages 75+ 199 162 234 203 167 238 159 117 198Ages lt65 251 204 307 257 210 314 208 166 262Ages 65+ 228 189 270 233 193 274 186 147 229

StagedAll Stages 237 195 283 241 199 287 197 157 245Localized 614 548 669 614 553 665 572 470 665Regional 345 299 397 345 299 397 316 282 354Distant 61 50 75 59 47 73 57 46 71UnstagedUnknown 146 138 154 138 128 149 113 103 125

Table 1514Non-Small Cell Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Survival Time

1-year 353 372 386 395 403 399 404 399 414 409 402 407 419 422 435 440 444 452 458 449 467 459 480 481 4982-year 211 220 226 237 249 247 247 252 258 258 256 265 265 277 285 295 301 310 314 311 328 318 336 3473-year 163 169 171 183 191 193 193 198 198 202 198 207 207 223 226 235 240 248 253 249 264 255 2724-year 139 145 146 155 165 162 165 170 170 175 168 175 179 189 195 200 206 214 216 215 229 2205-year 125 129 130 138 145 146 147 146 152 157 150 156 160 168 174 176 184 189 196 193 2046-year 114 117 119 126 132 132 133 133 137 142 135 141 145 154 158 162 168 173 179 1777-year 107 108 109 116 123 121 122 122 127 130 123 129 133 142 146 151 153 159 1658-year 100 100 101 107 114 112 113 112 118 120 115 119 120 132 135 140 142 1459-year 94 92 94 99 107 103 104 105 110 112 106 111 111 125 125 127 13310-year 88 86 88 92 100 95 98 100 105 104 101 103 103 116 116 11711-year 83 81 82 86 94 88 91 94 97 98 94 95 97 108 10812-year 78 77 77 80 89 83 85 89 91 91 88 88 92 10113-year 74 72 72 75 82 79 80 81 85 86 82 83 8614-year 71 68 68 71 77 76 75 76 80 80 77 7915-year 66 64 64 67 73 70 71 71 76 77 7216-year 63 60 61 62 69 67 65 67 72 7517-year 60 56 57 59 64 63 61 63 6818-year 57 53 53 55 59 60 57 6019-year 54 50 50 52 54 56 5420-year 52 46 47 49 52 5321-year 49 43 45 46 5022-year 47 41 42 4323-year 44 38 4024-year 42 36 3825-year 40 34 3626-year 38 32 3427-year 36 30 3328-year 35 2929-year 34 2730-year 32 26

Table 1515Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Survival Time

1-year 334 354 365 372 380 380 381 370 382 386 370 372 394 390 400 413 409 420 427 412 424 416 428 440 4662-year 195 202 210 216 231 230 230 226 227 237 222 231 237 247 248 268 262 278 276 273 285 280 279 3073-year 148 153 156 164 173 178 177 174 167 182 173 179 182 195 195 208 208 221 219 215 223 220 2194-year 125 129 131 136 148 146 150 147 141 155 143 150 155 166 166 173 175 189 184 185 190 1875-year 111 114 116 121 132 131 133 124 125 141 127 136 141 149 149 151 157 168 165 165 1676-year 101 104 106 110 118 117 119 110 112 126 116 122 126 136 133 140 142 153 151 1517-year 94 95 97 100 112 106 108 101 103 113 105 112 116 123 122 128 128 142 1388-year 88 87 90 91 102 98 100 90 95 107 96 101 108 114 112 119 116 1299-year 82 80 84 84 96 91 92 85 87 100 89 93 99 108 105 107 10810-year 77 74 79 79 88 82 86 80 83 91 84 86 89 100 96 9511-year 72 70 73 72 83 74 79 75 77 84 78 80 84 94 8812-year 67 66 68 67 80 69 72 70 72 78 73 74 81 8713-year 63 62 63 62 73 67 68 63 68 72 65 69 7614-year 60 58 60 58 69 63 64 59 63 67 62 6515-year 56 55 56 55 64 58 61 56 59 64 5516-year 53 50 53 51 62 54 57 52 58 6217-year 51 46 48 48 58 52 53 49 5418-year 47 44 45 45 53 49 49 4619-year 45 41 41 43 46 46 4520-year 42 38 39 40 43 4421-year 41 35 36 37 4122-year 39 33 34 3523-year 37 31 3224-year 34 28 3025-year 33 27 2826-year 31 25 2627-year 28 25 2528-year 28 2429-year 27 2230-year 26 21

Table 1516Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Survival Time

1-year 405 413 422 428 435 425 433 437 454 436 442 450 449 458 474 471 482 488 491 490 513 505 535 523 5332-year 253 257 255 267 274 269 269 284 295 285 297 305 299 312 324 325 343 346 356 353 373 359 396 3883-year 203 205 197 211 216 214 212 229 236 228 230 240 238 255 261 266 274 278 289 286 307 294 3274-year 178 178 172 183 188 183 185 199 205 199 199 204 206 214 227 230 238 241 251 248 271 2565-year 161 160 154 164 164 165 164 174 183 177 178 179 183 190 202 204 212 212 230 224 2426-year 150 146 141 151 150 152 150 161 168 161 158 164 168 176 185 188 196 195 209 2067-year 140 136 129 139 139 141 140 149 156 150 146 150 153 163 171 176 181 179 1958-year 131 128 120 130 131 131 128 139 147 136 138 140 136 153 160 164 169 1639-year 124 119 112 121 123 119 119 131 138 128 127 131 126 143 148 150 15910-year 116 111 104 113 116 111 112 124 131 120 122 123 118 133 139 14111-year 111 105 98 106 110 107 106 119 122 114 114 113 113 124 13112-year 106 99 92 99 101 101 99 113 114 107 107 105 106 11613-year 102 93 88 94 94 96 94 104 107 102 101 99 9914-year 97 89 82 90 87 91 89 97 100 96 95 9515-year 92 84 78 84 84 87 83 91 95 91 9216-year 89 80 74 79 79 82 76 86 89 9017-year 84 77 70 74 73 78 72 80 8518-year 80 72 67 70 68 74 67 7819-year 77 66 63 65 65 69 6420-year 74 63 61 62 63 6421-year 69 59 59 59 6022-year 65 56 55 5623-year 62 53 5424-year 60 51 5125-year 58 48 4926-year 56 46 4827-year 54 42 4628-year 52 4029-year 49 3730-year 46 36

Table 1517Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 634 497 Asian 0 000 000 001 541 406

10 000 001 003 641 503 Pacific 10 000 001 003 545 409

20 000 002 014 643 504 Islander 20 001 003 013 546 410

30 002 014 073 648 509 30 002 012 050 547 411

40 012 072 218 654 515 40 010 048 147 548 412

50 061 210 452 657 521 50 038 138 309 544 412

60 158 415 594 632 507 60 103 279 447 521 402

70 290 492 - 535 446 70 188 368 - 447 368

80 270 - - 327 301 80 213 - - 306 290

White 0 000 000 001 652 508 American 0 000 000 000 447 367

10 000 001 002 658 514 Indian 10 000 000 001 452 372

20 000 002 014 660 515 Alaska 20 000 001 007 454 374

30 002 014 073 665 520 Nativea 30 001 006 043 461 381

40 012 072 222 672 527 40 005 043 144 472 392

50 062 215 468 676 532 50 039 144 323 485 406

60 162 430 614 650 518 60 113 305 432 479 410

70 302 510 - 551 454 70 219 364 - 417 374

80 279 - - 334 305 80 194 - - 266 243

Black 0 000 000 001 569 454 Hispanicb 0 000 000 001 403 277

10 000 001 003 580 463 10 000 000 002 406 280

20 001 003 016 582 465 20 000 002 007 407 281

30 002 016 088 589 471 30 001 007 033 410 283

40 014 087 241 597 480 40 005 032 108 412 285

50 076 236 446 604 489 50 027 104 246 414 287

60 174 403 542 575 475 60 081 229 355 404 285

70 274 439 - 479 413 70 163 302 - 356 264

80 234 - - 290 281 80 173 - - 241 202

Table 1518

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2014-2016 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 670 549 Asian 0 000 000 001 657 502

10 000 001 002 678 556 Pacific 10 000 001 002 662 506

20 000 002 014 680 559 Islander 20 000 002 012 663 507

30 002 013 074 688 566 30 002 012 055 666 510

40 012 073 232 698 576 40 010 054 177 669 512

50 063 227 488 707 587 50 044 169 386 669 514

60 176 457 652 692 579 60 130 355 563 648 506

70 326 553 - 600 518 70 245 473 - 566 467

80 320 - - 386 365 80 281 - - 396 377

White 0 000 000 001 673 554 American 0 000 000 000 450 390

10 000 000 002 680 560 Indian 10 000 000 001 455 396

20 000 002 013 682 562 Alaska 20 000 001 005 458 399

30 002 013 072 690 570 Nativea 30 001 005 039 467 409

40 012 072 230 700 580 40 004 039 139 482 424

50 062 225 491 709 590 50 037 142 332 502 445

60 175 460 658 695 583 60 115 323 465 509 460

70 331 560 - 604 521 70 243 410 - 461 435

80 325 - - 386 366 80 235 - - 306 282

Black 0 000 000 001 659 545 Hispanicb 0 000 000 000 449 345

10 000 001 004 672 558 10 000 000 002 453 348

20 001 003 017 675 562 20 000 002 007 455 349

30 003 017 099 687 573 30 001 006 033 459 353

40 014 098 290 701 587 40 005 032 115 464 357

50 088 288 542 718 604 50 027 113 279 470 362

60 222 505 662 700 598 60 091 267 416 468 366

70 355 553 - 599 533 70 199 367 - 426 346

80 307 - - 379 376 80 222 - - 299 268

Table 1519

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2014-2016 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 605 450 Asian 0 000 000 001 446 330

10 000 001 003 610 454 Pacific 10 000 001 003 449 332

20 000 003 015 611 455 Islander 20 001 003 013 450 333

30 002 015 072 614 458 30 002 012 045 450 333

40 013 071 204 617 461 40 010 043 121 449 333

50 059 195 420 616 463 50 034 112 244 443 331

60 142 377 544 582 445 60 080 215 352 419 322

70 259 443 - 485 387 70 142 286 - 357 295

80 234 - - 288 257 80 165 - - 246 233

White 0 000 000 001 637 467 American 0 000 000 000 449 347

10 000 001 003 642 472 Indian 10 000 000 002 453 351

20 001 003 016 643 473 Alaska 20 000 001 008 454 353

30 002 015 075 646 475 Nativea 30 001 008 046 458 357

40 013 073 214 649 479 40 007 046 148 465 365

50 061 205 446 648 480 50 040 146 315 473 373

60 150 402 576 613 461 60 111 290 406 457 368

70 278 469 - 510 400 70 199 327 - 384 327

80 246 - - 297 262 80 165 - - 239 219

Black 0 000 000 001 497 377 Hispanicb 0 000 000 001 368 222

10 000 000 002 506 384 10 000 001 002 371 224

20 000 002 015 507 385 20 000 002 008 371 225

30 002 015 078 510 387 30 001 007 034 372 225

40 013 077 199 514 392 40 006 032 101 373 226

50 066 191 367 515 396 50 027 097 219 372 226

60 135 322 449 481 379 60 072 198 307 356 222

70 215 360 - 397 330 70 136 252 - 305 204

80 193 - - 242 229 80 140 - - 204 159

Table 1520

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2014-2016 By RaceEthnicity

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016

d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2012-2016 Trend 2007-2016c Trend 2007-2016d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 549 630 489 -22 -29 -17 -23 -28 -18

White 567 635 518 -22 -29 -16 -22 -28 -17White Hispanice 298 361 254 -25 -36 -13 - - -White Non-Hispanice 609 675 560 -20 -27 -14 - - -

Black 562 735 446 -25 -28 -17 -31 -30 -21

AsianPacific Islander 360 463 282 -10 -17 -06 - - -

Amer IndAlaska Natf 378 433 339 -17 -22 -11 - - -

Hispanice 291 352 248 -23 -34 -11 - - -

US Mortalityg Rate 2012-2016 Trend 2007-2016h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 419 516 344 -30 -36 -25

White 427 517 356 -29 -35 -24White Hispanice 192 266 138 -22 -30 -10White Non-Hispanice 450 541 380 -27 -34 -22

Black 443 621 324 -35 -41 -27

AsianPacific Islander 227 302 173 -19 -27 -13

Amer IndAlaska NatTotal US 277 336 231 -28 -23 -27PRCDA Counties 348 420 294 -14 -16 -17Non-PRCDA Counties 195 241 157 -28 -31 -26

Hispanice 183 253 131 -23 -31 -11

Table 1521Lung and Bronchus (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2012-2016

California 4205 4739 3807 4286 4687 3992 5213 6268 4472Greater Bay Area 4084 4614 3687 4071 4319 3900 5832 7047 4944San Francisco-Oakland 4196 4704 3819 4102 4255 4011 6125 7390 5219San Jose-Monterey 3869 4448 3429 4016 4432 3704 4034 5193 3016

Los Angeles 3656 4333 3160 3579 4142 3161 5079 6062 4441Greater California 4494 4960 4145 4613 4992 4334 5065 6122 4271

Connecticut 5981 6556 5581 6078 6567 5745 5431 7215 4325Detroit 7020 8019 6311 7009 7816 6447 7520 9442 6241Georgia 6405 8121 5129 6776 8272 5630 5689 8187 4048Atlanta 5182 6201 4476 5298 6017 4806 5310 7049 4214Rural Georgia 6457 9152 4365 6394 8484 4640 6569 11102 3671Greater Georgia 6978 8942 5484 7314 9052 5962 5970 8891 3981

Hawaii 4569 5716 3641 4535 4989 4067 4480 4418 -Idaho 5033 5558 4628 5036 5552 4638 - - -Iowa 6305 7498 5400 6309 7485 5418 7466 9252 6133Kentucky 9224 11124 7784 9314 11227 7860 8896 10724 7598Louisiana 6749 8476 5415 6701 7967 5718 7043 10244 4792Massachusetts 6181 6627 5907 6340 6729 6115 4533 5274 4055New Jersey 5613 6224 5203 5885 6408 5544 5353 6633 4589New Mexico 3957 4549 3488 4144 4718 3687 4639 5929 3662New York 5886 6698 5323 6243 6888 5809 4751 6135 3880Seattle-Puget Sound 5656 6206 5244 5786 6240 5446 6064 7410 4951Utah 2686 3151 2304 2678 3140 2298 4842 5008 4665

SEER 9 Areasb 5276 6015 4724 5361 5946 4928 6175 7837 5055SEER 13 Areasb 4849 5577 4306 4931 5511 4500 5877 7393 4854SEER 18 Areasb 5345 6194 4703 5495 6209 4956 5999 7881 4708SEER 21 Areasb 5488 6299 4888 5674 6349 5181 5620 7351 4459

Table 1522Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2012-2016

California 3080 3647 2649 3167 3637 2806 3958 4973 3245Greater Bay Area 2804 3289 2438 2856 3150 2635 4112 5160 3361San Francisco-Oakland 2913 3387 2561 2921 3165 2749 4376 5537 3557San Jose-Monterey 2593 3102 2200 2739 3123 2437 2431 2979 1966

Los Angeles 2739 3391 2259 2675 3217 2268 4095 5147 3406Greater California 3329 3881 2901 3438 3927 3059 3751 4730 3009

Connecticut 3579 4152 3162 3660 4170 3288 3208 4518 2400Detroit 4714 5655 4032 4663 5442 4099 5266 7024 4102Georgia 4458 5980 3332 4705 6068 3658 3981 6122 2613Atlanta 3461 4446 2779 3482 4233 2947 3609 5266 2613Rural Georgia 4746 6888 3144 4742 6473 3319 4797 8119 2767Greater Georgia 4912 6630 3610 5138 6695 3924 4246 6663 2630

Hawaii 3062 3913 2379 3230 3568 2877 3499 - -Idaho 3490 4036 3035 3522 4071 3064 - - -Iowa 4461 5593 3598 4465 5599 3601 5557 6541 4654Kentucky 6613 8455 5222 6697 8558 5282 6061 7822 4894Louisiana 5147 6744 3916 5055 6290 4083 5552 8403 3584Massachusetts 4048 4745 3557 4182 4850 3714 2898 3780 2281New Jersey 3660 4337 3181 3831 4467 3380 3751 5010 2966New Mexico 2996 3522 2579 3153 3674 2735 3181 4414 2131New York 3711 4511 3137 3971 4694 3448 3080 4202 2381Seattle-Puget Sound 3784 4387 3321 3912 4450 3494 3830 4807 2966Utah 1918 2345 1565 1921 2348 1568 3031 - -

SEER 9 Areasb 3558 4263 3026 3634 4238 3174 4230 5714 3240SEER 13 Areasb 3339 4029 2820 3405 3989 2959 4170 5553 3245SEER 18 Areasb 3759 4591 3125 3872 4612 3302 4337 6024 3193SEER 21 Areasb 3764 4578 3152 3904 4632 3352 3956 5487 2940

Total US 4186 5164 3436 4265 5171 3564 4435 6211 3235

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4186 005

High Five StatesKentucky 6613 051 01(0101) 5798c

Arkansas 5747 057 02(0205) 3731c

West Virginia 5699 068 03(0205) 3616c

Mississippi 5646 058 04(0205) 3489c

Tennessee 5586 038 05(0305) 3344c

Low Five StatesCalifornia 3080 013 47(4749) -2642c

Hawaii 3062 060 48(4650) -2685c

New Mexico 2996 050 49(4750) -2842c

Colorado 2931 034 50(4850) -2999c

Utah 1918 041 51(5151) -5418c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5192 043 09(0711) 2405c Montana 3873 078 36(3041) -747c

Alaska 4359 133 24(1434) 414 Nebraska 4125 063 30(2535) -146Arizona 3431 029 45(4346) -1803c Nevada 4339 054 26(1928) 366Arkansas 5747 057 02(0205) 3731c New Hampshire 4421 074 22(1727) 563c

California 3080 013 47(4749) -2642c New Jersey 3660 027 41(3943) -1256c

Colorado 2931 034 50(4850) -2999c New Mexico 2996 050 49(4750) -2842c

Connecticut 3579 041 42(4045) -1450c New York 3711 018 40(3842) -1135c

Delaware 4720 091 14(1320) 1276c North Carolina 4766 029 13(1317) 1385c

DC 3562 108 43(3646) -1489c North Dakota 3825 097 37(3143) -863c

Florida 4076 017 31(2834) -261 Ohio 5037 027 12(1012) 2033c

Georgia 4458 030 20(1725) 651c Oklahoma 5384 050 06(0608) 2862c

Hawaii 3062 060 48(4650) -2685c Oregon 4068 042 32(2735) -280Idaho 3490 063 44(4146) -1663c Pennsylvania 4392 023 23(1926) 494Illinois 4472 025 18(1724) 685c Rhode Island 4694 086 17(1320) 1213c

Indiana 5237 038 08(0610) 2510c South Carolina 4697 041 16(1318) 1221c

Iowa 4461 049 19(1726) 658c South Dakota 4179 092 28(2235) -016Kansas 4433 052 21(1726) 590c Tennessee 5586 038 05(0305) 3344c

Kentucky 6613 051 01(0101) 5798c Texas 3736 018 39(3741) -1073c

Louisiana 5147 045 10(0712) 2297c Utah 1918 041 51(5151) -5418c

Maine 5055 074 11(0712) 2076c Vermont 4344 105 25(1732) 378Maryland 4026 036 34(2936) -381 Virginia 4223 031 27(2530) 088Massachusetts 4048 032 33(2835) -329 Washington 3903 032 35(3438) -677c

Michigan 4698 028 15(1317) 1225c West Virginia 5699 068 03(0205) 3616c

Minnesota 3795 035 38(3540) -933c Wisconsin 4134 035 29(2634) -123Mississippi 5646 058 04(0205) 3489c Wyoming 3361 104 46(4147) -1971c

Missouri 5264 038 07(0610) 2576c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males and Females

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5164 008

High Five StatesKentucky 8455 088 01(0101) 6373c

Mississippi 7859 106 02(0203) 5219c

Arkansas 7570 098 03(0205) 4658c

Tennessee 7331 067 04(0306) 4195c

West Virginia 7253 115 05(0306) 4045c

Low Five StatesWyoming 3721 162 47(4250) -2795c

California 3647 021 48(4749) -2939c

New Mexico 3522 081 49(4750) -3180c

Colorado 3252 054 50(4950) -3703c

Utah 2345 067 51(5151) -5460c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7090 076 06(0406) 3728c Montana 4187 120 42(3847) -1892c

Alaska 5031 213 26(1738) -258 Nebraska 5049 104 25(2234) -224Arizona 4006 047 45(4247) -2242c Nevada 4757 084 33(2737) -789c

Arkansas 7570 098 03(0205) 4658c New Hampshire 5022 118 27(2235) -276California 3647 021 48(4749) -2939c New Jersey 4337 045 40(3843) -1602c

Colorado 3252 054 50(4950) -3703c New Mexico 3522 081 49(4750) -3180c

Connecticut 4152 067 43(4046) -1961c New York 4511 031 38(3540) -1265c

Delaware 5700 151 16(1423) 1038c North Carolina 6253 051 12(1114) 2109c

DC 4311 184 41(3147) -1652c North Dakota 4737 161 35(2541) -826c

Florida 4979 028 30(2531) -359 Ohio 6272 046 11(1114) 2146c

Georgia 5980 055 15(1416) 1579c Oklahoma 6720 084 08(0710) 3012c

Hawaii 3913 101 46(4248) -2423c Oregon 4649 067 36(3039) -997c

Idaho 4036 101 44(4147) -2184c Pennsylvania 5523 039 20(1722) 696c

Illinois 5481 043 21(1823) 613c Rhode Island 5638 144 18(1524) 917c

Indiana 6666 065 09(0710) 2909c South Carolina 6192 071 13(1115) 1990c

Iowa 5593 082 19(1622) 830c South Dakota 5240 153 24(1732) 148Kansas 5341 086 22(1826) 342 Tennessee 7331 067 04(0306) 4195c

Kentucky 8455 088 01(0101) 6373c Texas 4762 030 32(3036) -779c

Louisiana 6744 080 07(0710) 3060c Utah 2345 067 51(5151) -5460c

Maine 6172 123 14(1016) 1951c Vermont 5001 168 28(2037) -315Maryland 4850 060 31(2636) -609c Virginia 5296 053 23(2126) 255Massachusetts 4745 053 34(2937) -812c Washington 4516 052 37(3540) -1256c

Michigan 5647 047 17(1620) 935c West Virginia 7253 115 05(0306) 4045c

Minnesota 4412 057 39(3642) -1456c Wisconsin 4991 058 29(2432) -335Mississippi 7859 106 02(0203) 5219c Wyoming 3721 162 47(4250) -2795c

Missouri 6504 064 10(0811) 2595c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2012-2016

California 4205 4739 3807 4286 4687 3992 5213 6268 4472Greater Bay Area 4084 4614 3687 4071 4319 3900 5832 7047 4944San Francisco-Oakland 4196 4704 3819 4102 4255 4011 6125 7390 5219San Jose-Monterey 3869 4448 3429 4016 4432 3704 4034 5193 3016

Los Angeles 3656 4333 3160 3579 4142 3161 5079 6062 4441Greater California 4494 4960 4145 4613 4992 4334 5065 6122 4271

Connecticut 5981 6556 5581 6078 6567 5745 5431 7215 4325Detroit 7020 8019 6311 7009 7816 6447 7520 9442 6241Georgia 6405 8121 5129 6776 8272 5630 5689 8187 4048Atlanta 5182 6201 4476 5298 6017 4806 5310 7049 4214Rural Georgia 6457 9152 4365 6394 8484 4640 6569 11102 3671Greater Georgia 6978 8942 5484 7314 9052 5962 5970 8891 3981

Hawaii 4569 5716 3641 4535 4989 4067 4480 4418 -Idaho 5033 5558 4628 5036 5552 4638 - - -Iowa 6305 7498 5400 6309 7485 5418 7466 9252 6133Kentucky 9224 11124 7784 9314 11227 7860 8896 10724 7598Louisiana 6749 8476 5415 6701 7967 5718 7043 10244 4792Massachusetts 6181 6627 5907 6340 6729 6115 4533 5274 4055New Jersey 5613 6224 5203 5885 6408 5544 5353 6633 4589New Mexico 3957 4549 3488 4144 4718 3687 4639 5929 3662New York 5886 6698 5323 6243 6888 5809 4751 6135 3880Seattle-Puget Sound 5656 6206 5244 5786 6240 5446 6064 7410 4951Utah 2686 3151 2304 2678 3140 2298 4842 5008 4665

SEER 9 Areasb 5276 6015 4724 5361 5946 4928 6175 7837 5055SEER 13 Areasb 4849 5577 4306 4931 5511 4500 5877 7393 4854SEER 18 Areasb 5345 6194 4703 5495 6209 4956 5999 7881 4708SEER 21 Areasb 5488 6299 4888 5674 6349 5181 5620 7351 4459

Table 1522Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2012-2016

California 3080 3647 2649 3167 3637 2806 3958 4973 3245Greater Bay Area 2804 3289 2438 2856 3150 2635 4112 5160 3361San Francisco-Oakland 2913 3387 2561 2921 3165 2749 4376 5537 3557San Jose-Monterey 2593 3102 2200 2739 3123 2437 2431 2979 1966

Los Angeles 2739 3391 2259 2675 3217 2268 4095 5147 3406Greater California 3329 3881 2901 3438 3927 3059 3751 4730 3009

Connecticut 3579 4152 3162 3660 4170 3288 3208 4518 2400Detroit 4714 5655 4032 4663 5442 4099 5266 7024 4102Georgia 4458 5980 3332 4705 6068 3658 3981 6122 2613Atlanta 3461 4446 2779 3482 4233 2947 3609 5266 2613Rural Georgia 4746 6888 3144 4742 6473 3319 4797 8119 2767Greater Georgia 4912 6630 3610 5138 6695 3924 4246 6663 2630

Hawaii 3062 3913 2379 3230 3568 2877 3499 - -Idaho 3490 4036 3035 3522 4071 3064 - - -Iowa 4461 5593 3598 4465 5599 3601 5557 6541 4654Kentucky 6613 8455 5222 6697 8558 5282 6061 7822 4894Louisiana 5147 6744 3916 5055 6290 4083 5552 8403 3584Massachusetts 4048 4745 3557 4182 4850 3714 2898 3780 2281New Jersey 3660 4337 3181 3831 4467 3380 3751 5010 2966New Mexico 2996 3522 2579 3153 3674 2735 3181 4414 2131New York 3711 4511 3137 3971 4694 3448 3080 4202 2381Seattle-Puget Sound 3784 4387 3321 3912 4450 3494 3830 4807 2966Utah 1918 2345 1565 1921 2348 1568 3031 - -

SEER 9 Areasb 3558 4263 3026 3634 4238 3174 4230 5714 3240SEER 13 Areasb 3339 4029 2820 3405 3989 2959 4170 5553 3245SEER 18 Areasb 3759 4591 3125 3872 4612 3302 4337 6024 3193SEER 21 Areasb 3764 4578 3152 3904 4632 3352 3956 5487 2940

Total US 4186 5164 3436 4265 5171 3564 4435 6211 3235

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4186 005

High Five StatesKentucky 6613 051 01(0101) 5798c

Arkansas 5747 057 02(0205) 3731c

West Virginia 5699 068 03(0205) 3616c

Mississippi 5646 058 04(0205) 3489c

Tennessee 5586 038 05(0305) 3344c

Low Five StatesCalifornia 3080 013 47(4749) -2642c

Hawaii 3062 060 48(4650) -2685c

New Mexico 2996 050 49(4750) -2842c

Colorado 2931 034 50(4850) -2999c

Utah 1918 041 51(5151) -5418c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5192 043 09(0711) 2405c Montana 3873 078 36(3041) -747c

Alaska 4359 133 24(1434) 414 Nebraska 4125 063 30(2535) -146Arizona 3431 029 45(4346) -1803c Nevada 4339 054 26(1928) 366Arkansas 5747 057 02(0205) 3731c New Hampshire 4421 074 22(1727) 563c

California 3080 013 47(4749) -2642c New Jersey 3660 027 41(3943) -1256c

Colorado 2931 034 50(4850) -2999c New Mexico 2996 050 49(4750) -2842c

Connecticut 3579 041 42(4045) -1450c New York 3711 018 40(3842) -1135c

Delaware 4720 091 14(1320) 1276c North Carolina 4766 029 13(1317) 1385c

DC 3562 108 43(3646) -1489c North Dakota 3825 097 37(3143) -863c

Florida 4076 017 31(2834) -261 Ohio 5037 027 12(1012) 2033c

Georgia 4458 030 20(1725) 651c Oklahoma 5384 050 06(0608) 2862c

Hawaii 3062 060 48(4650) -2685c Oregon 4068 042 32(2735) -280Idaho 3490 063 44(4146) -1663c Pennsylvania 4392 023 23(1926) 494Illinois 4472 025 18(1724) 685c Rhode Island 4694 086 17(1320) 1213c

Indiana 5237 038 08(0610) 2510c South Carolina 4697 041 16(1318) 1221c

Iowa 4461 049 19(1726) 658c South Dakota 4179 092 28(2235) -016Kansas 4433 052 21(1726) 590c Tennessee 5586 038 05(0305) 3344c

Kentucky 6613 051 01(0101) 5798c Texas 3736 018 39(3741) -1073c

Louisiana 5147 045 10(0712) 2297c Utah 1918 041 51(5151) -5418c

Maine 5055 074 11(0712) 2076c Vermont 4344 105 25(1732) 378Maryland 4026 036 34(2936) -381 Virginia 4223 031 27(2530) 088Massachusetts 4048 032 33(2835) -329 Washington 3903 032 35(3438) -677c

Michigan 4698 028 15(1317) 1225c West Virginia 5699 068 03(0205) 3616c

Minnesota 3795 035 38(3540) -933c Wisconsin 4134 035 29(2634) -123Mississippi 5646 058 04(0205) 3489c Wyoming 3361 104 46(4147) -1971c

Missouri 5264 038 07(0610) 2576c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males and Females

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5164 008

High Five StatesKentucky 8455 088 01(0101) 6373c

Mississippi 7859 106 02(0203) 5219c

Arkansas 7570 098 03(0205) 4658c

Tennessee 7331 067 04(0306) 4195c

West Virginia 7253 115 05(0306) 4045c

Low Five StatesWyoming 3721 162 47(4250) -2795c

California 3647 021 48(4749) -2939c

New Mexico 3522 081 49(4750) -3180c

Colorado 3252 054 50(4950) -3703c

Utah 2345 067 51(5151) -5460c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7090 076 06(0406) 3728c Montana 4187 120 42(3847) -1892c

Alaska 5031 213 26(1738) -258 Nebraska 5049 104 25(2234) -224Arizona 4006 047 45(4247) -2242c Nevada 4757 084 33(2737) -789c

Arkansas 7570 098 03(0205) 4658c New Hampshire 5022 118 27(2235) -276California 3647 021 48(4749) -2939c New Jersey 4337 045 40(3843) -1602c

Colorado 3252 054 50(4950) -3703c New Mexico 3522 081 49(4750) -3180c

Connecticut 4152 067 43(4046) -1961c New York 4511 031 38(3540) -1265c

Delaware 5700 151 16(1423) 1038c North Carolina 6253 051 12(1114) 2109c

DC 4311 184 41(3147) -1652c North Dakota 4737 161 35(2541) -826c

Florida 4979 028 30(2531) -359 Ohio 6272 046 11(1114) 2146c

Georgia 5980 055 15(1416) 1579c Oklahoma 6720 084 08(0710) 3012c

Hawaii 3913 101 46(4248) -2423c Oregon 4649 067 36(3039) -997c

Idaho 4036 101 44(4147) -2184c Pennsylvania 5523 039 20(1722) 696c

Illinois 5481 043 21(1823) 613c Rhode Island 5638 144 18(1524) 917c

Indiana 6666 065 09(0710) 2909c South Carolina 6192 071 13(1115) 1990c

Iowa 5593 082 19(1622) 830c South Dakota 5240 153 24(1732) 148Kansas 5341 086 22(1826) 342 Tennessee 7331 067 04(0306) 4195c

Kentucky 8455 088 01(0101) 6373c Texas 4762 030 32(3036) -779c

Louisiana 6744 080 07(0710) 3060c Utah 2345 067 51(5151) -5460c

Maine 6172 123 14(1016) 1951c Vermont 5001 168 28(2037) -315Maryland 4850 060 31(2636) -609c Virginia 5296 053 23(2126) 255Massachusetts 4745 053 34(2937) -812c Washington 4516 052 37(3540) -1256c

Michigan 5647 047 17(1620) 935c West Virginia 7253 115 05(0306) 4045c

Minnesota 4412 057 39(3642) -1456c Wisconsin 4991 058 29(2432) -335Mississippi 7859 106 02(0203) 5219c Wyoming 3721 162 47(4250) -2795c

Missouri 6504 064 10(0811) 2595c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2012-2016

California 3080 3647 2649 3167 3637 2806 3958 4973 3245Greater Bay Area 2804 3289 2438 2856 3150 2635 4112 5160 3361San Francisco-Oakland 2913 3387 2561 2921 3165 2749 4376 5537 3557San Jose-Monterey 2593 3102 2200 2739 3123 2437 2431 2979 1966

Los Angeles 2739 3391 2259 2675 3217 2268 4095 5147 3406Greater California 3329 3881 2901 3438 3927 3059 3751 4730 3009

Connecticut 3579 4152 3162 3660 4170 3288 3208 4518 2400Detroit 4714 5655 4032 4663 5442 4099 5266 7024 4102Georgia 4458 5980 3332 4705 6068 3658 3981 6122 2613Atlanta 3461 4446 2779 3482 4233 2947 3609 5266 2613Rural Georgia 4746 6888 3144 4742 6473 3319 4797 8119 2767Greater Georgia 4912 6630 3610 5138 6695 3924 4246 6663 2630

Hawaii 3062 3913 2379 3230 3568 2877 3499 - -Idaho 3490 4036 3035 3522 4071 3064 - - -Iowa 4461 5593 3598 4465 5599 3601 5557 6541 4654Kentucky 6613 8455 5222 6697 8558 5282 6061 7822 4894Louisiana 5147 6744 3916 5055 6290 4083 5552 8403 3584Massachusetts 4048 4745 3557 4182 4850 3714 2898 3780 2281New Jersey 3660 4337 3181 3831 4467 3380 3751 5010 2966New Mexico 2996 3522 2579 3153 3674 2735 3181 4414 2131New York 3711 4511 3137 3971 4694 3448 3080 4202 2381Seattle-Puget Sound 3784 4387 3321 3912 4450 3494 3830 4807 2966Utah 1918 2345 1565 1921 2348 1568 3031 - -

SEER 9 Areasb 3558 4263 3026 3634 4238 3174 4230 5714 3240SEER 13 Areasb 3339 4029 2820 3405 3989 2959 4170 5553 3245SEER 18 Areasb 3759 4591 3125 3872 4612 3302 4337 6024 3193SEER 21 Areasb 3764 4578 3152 3904 4632 3352 3956 5487 2940

Total US 4186 5164 3436 4265 5171 3564 4435 6211 3235

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4186 005

High Five StatesKentucky 6613 051 01(0101) 5798c

Arkansas 5747 057 02(0205) 3731c

West Virginia 5699 068 03(0205) 3616c

Mississippi 5646 058 04(0205) 3489c

Tennessee 5586 038 05(0305) 3344c

Low Five StatesCalifornia 3080 013 47(4749) -2642c

Hawaii 3062 060 48(4650) -2685c

New Mexico 2996 050 49(4750) -2842c

Colorado 2931 034 50(4850) -2999c

Utah 1918 041 51(5151) -5418c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5192 043 09(0711) 2405c Montana 3873 078 36(3041) -747c

Alaska 4359 133 24(1434) 414 Nebraska 4125 063 30(2535) -146Arizona 3431 029 45(4346) -1803c Nevada 4339 054 26(1928) 366Arkansas 5747 057 02(0205) 3731c New Hampshire 4421 074 22(1727) 563c

California 3080 013 47(4749) -2642c New Jersey 3660 027 41(3943) -1256c

Colorado 2931 034 50(4850) -2999c New Mexico 2996 050 49(4750) -2842c

Connecticut 3579 041 42(4045) -1450c New York 3711 018 40(3842) -1135c

Delaware 4720 091 14(1320) 1276c North Carolina 4766 029 13(1317) 1385c

DC 3562 108 43(3646) -1489c North Dakota 3825 097 37(3143) -863c

Florida 4076 017 31(2834) -261 Ohio 5037 027 12(1012) 2033c

Georgia 4458 030 20(1725) 651c Oklahoma 5384 050 06(0608) 2862c

Hawaii 3062 060 48(4650) -2685c Oregon 4068 042 32(2735) -280Idaho 3490 063 44(4146) -1663c Pennsylvania 4392 023 23(1926) 494Illinois 4472 025 18(1724) 685c Rhode Island 4694 086 17(1320) 1213c

Indiana 5237 038 08(0610) 2510c South Carolina 4697 041 16(1318) 1221c

Iowa 4461 049 19(1726) 658c South Dakota 4179 092 28(2235) -016Kansas 4433 052 21(1726) 590c Tennessee 5586 038 05(0305) 3344c

Kentucky 6613 051 01(0101) 5798c Texas 3736 018 39(3741) -1073c

Louisiana 5147 045 10(0712) 2297c Utah 1918 041 51(5151) -5418c

Maine 5055 074 11(0712) 2076c Vermont 4344 105 25(1732) 378Maryland 4026 036 34(2936) -381 Virginia 4223 031 27(2530) 088Massachusetts 4048 032 33(2835) -329 Washington 3903 032 35(3438) -677c

Michigan 4698 028 15(1317) 1225c West Virginia 5699 068 03(0205) 3616c

Minnesota 3795 035 38(3540) -933c Wisconsin 4134 035 29(2634) -123Mississippi 5646 058 04(0205) 3489c Wyoming 3361 104 46(4147) -1971c

Missouri 5264 038 07(0610) 2576c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males and Females

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5164 008

High Five StatesKentucky 8455 088 01(0101) 6373c

Mississippi 7859 106 02(0203) 5219c

Arkansas 7570 098 03(0205) 4658c

Tennessee 7331 067 04(0306) 4195c

West Virginia 7253 115 05(0306) 4045c

Low Five StatesWyoming 3721 162 47(4250) -2795c

California 3647 021 48(4749) -2939c

New Mexico 3522 081 49(4750) -3180c

Colorado 3252 054 50(4950) -3703c

Utah 2345 067 51(5151) -5460c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7090 076 06(0406) 3728c Montana 4187 120 42(3847) -1892c

Alaska 5031 213 26(1738) -258 Nebraska 5049 104 25(2234) -224Arizona 4006 047 45(4247) -2242c Nevada 4757 084 33(2737) -789c

Arkansas 7570 098 03(0205) 4658c New Hampshire 5022 118 27(2235) -276California 3647 021 48(4749) -2939c New Jersey 4337 045 40(3843) -1602c

Colorado 3252 054 50(4950) -3703c New Mexico 3522 081 49(4750) -3180c

Connecticut 4152 067 43(4046) -1961c New York 4511 031 38(3540) -1265c

Delaware 5700 151 16(1423) 1038c North Carolina 6253 051 12(1114) 2109c

DC 4311 184 41(3147) -1652c North Dakota 4737 161 35(2541) -826c

Florida 4979 028 30(2531) -359 Ohio 6272 046 11(1114) 2146c

Georgia 5980 055 15(1416) 1579c Oklahoma 6720 084 08(0710) 3012c

Hawaii 3913 101 46(4248) -2423c Oregon 4649 067 36(3039) -997c

Idaho 4036 101 44(4147) -2184c Pennsylvania 5523 039 20(1722) 696c

Illinois 5481 043 21(1823) 613c Rhode Island 5638 144 18(1524) 917c

Indiana 6666 065 09(0710) 2909c South Carolina 6192 071 13(1115) 1990c

Iowa 5593 082 19(1622) 830c South Dakota 5240 153 24(1732) 148Kansas 5341 086 22(1826) 342 Tennessee 7331 067 04(0306) 4195c

Kentucky 8455 088 01(0101) 6373c Texas 4762 030 32(3036) -779c

Louisiana 6744 080 07(0710) 3060c Utah 2345 067 51(5151) -5460c

Maine 6172 123 14(1016) 1951c Vermont 5001 168 28(2037) -315Maryland 4850 060 31(2636) -609c Virginia 5296 053 23(2126) 255Massachusetts 4745 053 34(2937) -812c Washington 4516 052 37(3540) -1256c

Michigan 5647 047 17(1620) 935c West Virginia 7253 115 05(0306) 4045c

Minnesota 4412 057 39(3642) -1456c Wisconsin 4991 058 29(2432) -335Mississippi 7859 106 02(0203) 5219c Wyoming 3721 162 47(4250) -2795c

Missouri 6504 064 10(0811) 2595c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4186 005

High Five StatesKentucky 6613 051 01(0101) 5798c

Arkansas 5747 057 02(0205) 3731c

West Virginia 5699 068 03(0205) 3616c

Mississippi 5646 058 04(0205) 3489c

Tennessee 5586 038 05(0305) 3344c

Low Five StatesCalifornia 3080 013 47(4749) -2642c

Hawaii 3062 060 48(4650) -2685c

New Mexico 2996 050 49(4750) -2842c

Colorado 2931 034 50(4850) -2999c

Utah 1918 041 51(5151) -5418c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5192 043 09(0711) 2405c Montana 3873 078 36(3041) -747c

Alaska 4359 133 24(1434) 414 Nebraska 4125 063 30(2535) -146Arizona 3431 029 45(4346) -1803c Nevada 4339 054 26(1928) 366Arkansas 5747 057 02(0205) 3731c New Hampshire 4421 074 22(1727) 563c

California 3080 013 47(4749) -2642c New Jersey 3660 027 41(3943) -1256c

Colorado 2931 034 50(4850) -2999c New Mexico 2996 050 49(4750) -2842c

Connecticut 3579 041 42(4045) -1450c New York 3711 018 40(3842) -1135c

Delaware 4720 091 14(1320) 1276c North Carolina 4766 029 13(1317) 1385c

DC 3562 108 43(3646) -1489c North Dakota 3825 097 37(3143) -863c

Florida 4076 017 31(2834) -261 Ohio 5037 027 12(1012) 2033c

Georgia 4458 030 20(1725) 651c Oklahoma 5384 050 06(0608) 2862c

Hawaii 3062 060 48(4650) -2685c Oregon 4068 042 32(2735) -280Idaho 3490 063 44(4146) -1663c Pennsylvania 4392 023 23(1926) 494Illinois 4472 025 18(1724) 685c Rhode Island 4694 086 17(1320) 1213c

Indiana 5237 038 08(0610) 2510c South Carolina 4697 041 16(1318) 1221c

Iowa 4461 049 19(1726) 658c South Dakota 4179 092 28(2235) -016Kansas 4433 052 21(1726) 590c Tennessee 5586 038 05(0305) 3344c

Kentucky 6613 051 01(0101) 5798c Texas 3736 018 39(3741) -1073c

Louisiana 5147 045 10(0712) 2297c Utah 1918 041 51(5151) -5418c

Maine 5055 074 11(0712) 2076c Vermont 4344 105 25(1732) 378Maryland 4026 036 34(2936) -381 Virginia 4223 031 27(2530) 088Massachusetts 4048 032 33(2835) -329 Washington 3903 032 35(3438) -677c

Michigan 4698 028 15(1317) 1225c West Virginia 5699 068 03(0205) 3616c

Minnesota 3795 035 38(3540) -933c Wisconsin 4134 035 29(2634) -123Mississippi 5646 058 04(0205) 3489c Wyoming 3361 104 46(4147) -1971c

Missouri 5264 038 07(0610) 2576c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males and Females

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5164 008

High Five StatesKentucky 8455 088 01(0101) 6373c

Mississippi 7859 106 02(0203) 5219c

Arkansas 7570 098 03(0205) 4658c

Tennessee 7331 067 04(0306) 4195c

West Virginia 7253 115 05(0306) 4045c

Low Five StatesWyoming 3721 162 47(4250) -2795c

California 3647 021 48(4749) -2939c

New Mexico 3522 081 49(4750) -3180c

Colorado 3252 054 50(4950) -3703c

Utah 2345 067 51(5151) -5460c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7090 076 06(0406) 3728c Montana 4187 120 42(3847) -1892c

Alaska 5031 213 26(1738) -258 Nebraska 5049 104 25(2234) -224Arizona 4006 047 45(4247) -2242c Nevada 4757 084 33(2737) -789c

Arkansas 7570 098 03(0205) 4658c New Hampshire 5022 118 27(2235) -276California 3647 021 48(4749) -2939c New Jersey 4337 045 40(3843) -1602c

Colorado 3252 054 50(4950) -3703c New Mexico 3522 081 49(4750) -3180c

Connecticut 4152 067 43(4046) -1961c New York 4511 031 38(3540) -1265c

Delaware 5700 151 16(1423) 1038c North Carolina 6253 051 12(1114) 2109c

DC 4311 184 41(3147) -1652c North Dakota 4737 161 35(2541) -826c

Florida 4979 028 30(2531) -359 Ohio 6272 046 11(1114) 2146c

Georgia 5980 055 15(1416) 1579c Oklahoma 6720 084 08(0710) 3012c

Hawaii 3913 101 46(4248) -2423c Oregon 4649 067 36(3039) -997c

Idaho 4036 101 44(4147) -2184c Pennsylvania 5523 039 20(1722) 696c

Illinois 5481 043 21(1823) 613c Rhode Island 5638 144 18(1524) 917c

Indiana 6666 065 09(0710) 2909c South Carolina 6192 071 13(1115) 1990c

Iowa 5593 082 19(1622) 830c South Dakota 5240 153 24(1732) 148Kansas 5341 086 22(1826) 342 Tennessee 7331 067 04(0306) 4195c

Kentucky 8455 088 01(0101) 6373c Texas 4762 030 32(3036) -779c

Louisiana 6744 080 07(0710) 3060c Utah 2345 067 51(5151) -5460c

Maine 6172 123 14(1016) 1951c Vermont 5001 168 28(2037) -315Maryland 4850 060 31(2636) -609c Virginia 5296 053 23(2126) 255Massachusetts 4745 053 34(2937) -812c Washington 4516 052 37(3540) -1256c

Michigan 5647 047 17(1620) 935c West Virginia 7253 115 05(0306) 4045c

Minnesota 4412 057 39(3642) -1456c Wisconsin 4991 058 29(2432) -335Mississippi 7859 106 02(0203) 5219c Wyoming 3721 162 47(4250) -2795c

Missouri 6504 064 10(0811) 2595c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5164 008

High Five StatesKentucky 8455 088 01(0101) 6373c

Mississippi 7859 106 02(0203) 5219c

Arkansas 7570 098 03(0205) 4658c

Tennessee 7331 067 04(0306) 4195c

West Virginia 7253 115 05(0306) 4045c

Low Five StatesWyoming 3721 162 47(4250) -2795c

California 3647 021 48(4749) -2939c

New Mexico 3522 081 49(4750) -3180c

Colorado 3252 054 50(4950) -3703c

Utah 2345 067 51(5151) -5460c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7090 076 06(0406) 3728c Montana 4187 120 42(3847) -1892c

Alaska 5031 213 26(1738) -258 Nebraska 5049 104 25(2234) -224Arizona 4006 047 45(4247) -2242c Nevada 4757 084 33(2737) -789c

Arkansas 7570 098 03(0205) 4658c New Hampshire 5022 118 27(2235) -276California 3647 021 48(4749) -2939c New Jersey 4337 045 40(3843) -1602c

Colorado 3252 054 50(4950) -3703c New Mexico 3522 081 49(4750) -3180c

Connecticut 4152 067 43(4046) -1961c New York 4511 031 38(3540) -1265c

Delaware 5700 151 16(1423) 1038c North Carolina 6253 051 12(1114) 2109c

DC 4311 184 41(3147) -1652c North Dakota 4737 161 35(2541) -826c

Florida 4979 028 30(2531) -359 Ohio 6272 046 11(1114) 2146c

Georgia 5980 055 15(1416) 1579c Oklahoma 6720 084 08(0710) 3012c

Hawaii 3913 101 46(4248) -2423c Oregon 4649 067 36(3039) -997c

Idaho 4036 101 44(4147) -2184c Pennsylvania 5523 039 20(1722) 696c

Illinois 5481 043 21(1823) 613c Rhode Island 5638 144 18(1524) 917c

Indiana 6666 065 09(0710) 2909c South Carolina 6192 071 13(1115) 1990c

Iowa 5593 082 19(1622) 830c South Dakota 5240 153 24(1732) 148Kansas 5341 086 22(1826) 342 Tennessee 7331 067 04(0306) 4195c

Kentucky 8455 088 01(0101) 6373c Texas 4762 030 32(3036) -779c

Louisiana 6744 080 07(0710) 3060c Utah 2345 067 51(5151) -5460c

Maine 6172 123 14(1016) 1951c Vermont 5001 168 28(2037) -315Maryland 4850 060 31(2636) -609c Virginia 5296 053 23(2126) 255Massachusetts 4745 053 34(2937) -812c Washington 4516 052 37(3540) -1256c

Michigan 5647 047 17(1620) 935c West Virginia 7253 115 05(0306) 4045c

Minnesota 4412 057 39(3642) -1456c Wisconsin 4991 058 29(2432) -335Mississippi 7859 106 02(0203) 5219c Wyoming 3721 162 47(4250) -2795c

Missouri 6504 064 10(0811) 2595c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Males

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3436 006

High Five StatesKentucky 5222 061 01(0101) 5196c

West Virginia 4505 083 02(0206) 3111c

Oklahoma 4339 061 03(0208) 2627c

Missouri 4318 047 04(0208) 2566c

Arkansas 4303 067 05(0210) 2523c

Low Five StatesColorado 2686 044 47(4649) -2184c

California 2649 016 48(4749) -2293c

New Mexico 2579 063 49(4750) -2494c

Hawaii 2379 072 50(4950) -3078c

Utah 1565 050 51(5151) -5447c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3772 049 19(1524) 976 Montana 3642 104 23(1436) 599Alaska 3779 169 18(0537) 999 Nebraska 3431 078 30(2239) -015Arizona 2952 037 45(4146) -1409c Nevada 3984 072 14(0719) 1592c

Arkansas 4303 067 05(0210) 2523c New Hampshire 3987 096 12(0521) 1601c

California 2649 016 48(4749) -2293c New Jersey 3181 033 38(3743) -742Colorado 2686 044 47(4649) -2184c New Mexico 2579 063 49(4750) -2494c

Connecticut 3162 051 39(3644) -800 New York 3137 022 40(3844) -871Delaware 3986 112 13(0422) 1601c North Carolina 3655 034 22(1827) 637DC 3005 131 44(3248) -1255c North Dakota 3129 121 41(2946) -894Florida 3335 021 36(3238) -295 Ohio 4111 033 09(0613) 1963c

Georgia 3332 035 37(3039) -302 Oklahoma 4339 061 03(0208) 2627c

Hawaii 2379 072 50(4950) -3078c Oregon 3622 053 24(1831) 541Idaho 3035 081 43(3746) -1166c Pennsylvania 3560 028 26(2231) 360Illinois 3734 031 20(1724) 866 Rhode Island 4045 107 10(0320) 1772c

Indiana 4154 045 08(0513) 2089c South Carolina 3554 047 28(2133) 341Iowa 3598 060 25(1832) 471 South Dakota 3397 114 34(2043) -115Kansas 3731 065 21(1528) 858 Tennessee 4266 045 06(0309) 2416c

Kentucky 5222 061 01(0101) 5196c Texas 2946 021 46(4246) -1428c

Louisiana 3916 053 16(1020) 1397c Utah 1565 050 51(5151) -5447c

Maine 4185 092 07(0215) 2180c Vermont 3830 134 17(0731) 1147c

Maryland 3424 044 32(2637) -035 Virginia 3400 037 33(2837) -105Massachusetts 3557 040 27(2132) 352 Washington 3427 041 31(2737) -028Michigan 3977 035 15(0918) 1573c West Virginia 4505 083 02(0206) 3111c

Minnesota 3338 045 35(2939) -287 Wisconsin 3494 044 29(2335) 167Mississippi 3999 066 11(0718) 1637c Wyoming 3104 139 42(2846) -968Missouri 4318 047 04(0208) 2566c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016

Females

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years

b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee

Race Sex All Races Both Sexes 296258 106837 52045 27542 12276 494958 43284 538243

Males 135269 44604 20996 11092 5095 217057 22799 239856Females 160989 62233 31049 16450 7181 277901 20485 298387

White Both Sexes 247227 91706 45073 24033 10557 418596 26947 447921Males 112082 37908 17888 9484 4290 181652 12781 195508Females 135145 53798 27185 14548 6267 236944 14166 252413

Black Both Sexes 34379 10866 5121 2396 1283 54045 2986 57031Males 16053 4731 2283 1075 592 24734 1520 26254Females 18326 6134 2838 1322 691 29311 1466 30777

Asian Both Sexes 11557 3291 1527 827 294 17495 + +Pacific Males 5652 1530 702 404 144 8433 + +Islander Females 5905 1761 824 423 150 9063 + +

Hispanic Both Sexes 12554 4359 2023 1048 477 20462 + +Males 5566 1752 878 418 203 8817 + +Females 6988 2607 1145 630 274 11645 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01536 00002 00005 00017 00063 00250 01217 03745 08893 09606 01308

Males 01368 00002 00006 00016 00057 00217 01031 03611 08754 10432 01290Females 01699 00002 00003 00019 00069 00283 01395 03867 09009 09099 01332

White Both Sexes 01660 00002 00005 00018 00066 00251 01165 03666 09048 09817 01313Males 01454 00002 00006 00015 00058 00217 00977 03429 08725 10468 01270Females 01863 00002 00005 00022 00074 00286 01348 03885 09322 09410 01358

Black Both Sexes 01198 00004 00004 00017 00058 00254 01655 04706 08818 08197 01378Males 01143 00004 00008 00024 00066 00232 01414 05274 09944 10415 01534Females 01249 00003 - 00010 00050 00274 01864 04251 08034 07103 01286

Asian Both Sexes 00859 - - 00011 00048 00214 00938 02817 06035 07546 00963Pacific Males 00864 - - 00012 00037 00181 00915 03086 06896 09019 01076Islander Females 00854 - - 00011 00058 00243 00959 02599 05343 06598 00882

Hispanic Both Sexes 00358 00001 00002 00015 00040 00126 00507 01569 04091 05149 00619Males 00306 00001 00003 00011 00034 00122 00426 01436 03983 05928 00618Females 00412 - 00001 00019 00047 00130 00586 01687 04173 04668 00626

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 485 316080 997 260060 997 34701 998 18892 998 1034 999 19066 996

Small cell (80028041-8045) 60 39940 126 34975 134 3370 97 1314 69 155 150 2003 105

Non-small cell 410 266983 843 217675 835 30163 867 17090 902 838 810 16430 858

Squamous and 112 71874 227 60221 231 8268 238 2806 148 306 296 3670 192

transitional celld

Adenocarcinomae 241 157488 497 126234 484 17558 505 12531 662 417 403 10141 530

Large cellf 07 4384 14 3589 14 600 17 173 09 - - 231 12

Non-small cell carcinomag 25 16061 51 12974 50 2098 60 847 45 67 65 1028 54

Other specified carcinomash 27 17176 54 14657 56 1639 47 733 39 40 39 1360 71

Carcinoma NOSi 14 9157 29 7410 28 1168 34 488 26 41 40 633 33

Sarcomaj 01 522 02 436 02 49 01 30 02 - - 64 03

Other specified typesk 00 279 01 225 01 36 01 17 01 - - 21 01

Total 486 316881 1000 260721 1000 34786 1000 18939 1000 1035 1000 19151 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 553 161224 997 130797 997 18698 997 10516 997 492 998 9801 995

Small cell (80028041-8045) 65 19495 121 16754 128 1665 89 931 88 71 144 1032 105

Non-small cell 470 136635 845 110002 839 16327 871 9287 881 398 807 8409 854

Squamous and 153 44154 273 36644 279 5080 271 2074 197 174 353 2272 231

transitional celld

Adenocarcinomae 251 73378 454 57902 441 8854 472 6129 581 161 327 4845 492

Large cellf 08 2463 15 1979 15 355 19 116 11 - - 141 14

Non-small cell carcinomag 31 9059 56 7150 55 1271 68 560 53 39 79 572 58

Other specified carcinomash 26 7581 47 6327 48 767 41 408 39 21 43 579 59

Carcinoma NOSi 18 5094 32 4041 31 706 38 298 28 23 47 360 37

Sarcomaj 01 321 02 271 02 27 01 19 02 - - 35 04

Other specified typesk 01 148 01 118 01 20 01 - - - - - -

Total 554 161693 1000 131186 1000 18745 1000 10544 1000 493 1000 9846 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Males by Race

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 434 154856 998 129263 998 16003 998 8376 998 542 1000 9265 996

Small cell (80028041-8045) 57 20445 132 18221 141 1705 106 383 46 84 155 971 104

Non-small cell 366 130348 840 107673 831 13836 863 7803 929 440 812 8021 862

Squamous and 78 27720 179 23577 182 3188 199 732 87 132 244 1398 150

transitional celld

Adenocarcinomae 235 84110 542 68332 528 8704 543 6402 763 256 472 5296 569

Large cellf 05 1921 12 1610 12 245 15 57 07 - - 90 10

Non-small cell carcinomag 20 7002 45 5824 45 827 52 287 34 28 52 456 49

Other specified carcinomash 27 9595 62 8330 64 872 54 325 39 19 35 781 84

Carcinoma NOSi 11 4063 26 3369 26 462 29 190 23 18 33 273 29

Sarcomaj 01 201 01 165 01 22 01 - - - - 29 03

Other specified typesk 00 131 01 107 01 16 01 - - - - - -

Total 435 155188 1000 129535 1000 16041 1000 8395 1000 542 1000 9305 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2012-2016Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

0

30

60

90

120

150

180

1975 1985 1995 2005 20160

30

60

90

120

150

180

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2007-16 = -27Observed 2008-16 = -30

US Mortality APC2012-16 = -42

SEER Incidence APCsDelay Adj 1998-16 = -29Observed 1998-16 = -30

US Mortality APC2013-16 = -56

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -17

US Mortality APC2014-16 = -40

SEER Incidence APCsDelay Adj 2006-16 = -19Observed 2006-16 = -21

US Mortality APC2013-16 = -45

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 20160

20

40

60

80

100

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2014-16 = -03Observed 2010-16 = -25

US Mortality APC2002-16 = -37

SEER Incidence APCsDelay Adj 2003-16 = -50Observed 2003-16 = -51

US Mortality APC2005-16 = -51

SEER Incidence APCsDelay Adj 2012-16 = 01Observed 2012-16 = -02

US Mortality APC2003-16 = -28

SEER Incidence APCsDelay Adj 2005-16 = -30Observed 2005-16 = -32

US Mortality APC2005-16 = -36

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 20160

100

200

300

400

1975 1985 1995 2005 2016

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-16 = -30Observed 2009-16 = -32

US Mortality APC2012-16 = -42 SEER Incidence APCs

Delay Adj 1997-16 = -21Observed 1997-16 = -22

US Mortality APC2013-16 = -55

SEER Incidence APCsDelay Adj 2007-16 = -15Observed 2007-16 = -16

US Mortality APC2009-16 = -24

SEER Incidence APCsDelay Adj 2006-16 = -15Observed 2006-16 = -16

US Mortality APC2013-16 = -43

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20160

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2016

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2016N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2016

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2016 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2016

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2016

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival

Figure 157

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2016 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - 5-Year SEER Conditional Relative Survival