33
SEER Cancer Statistics Review 1975-2017 National Cancer Institute Joinpoint Regression Program Version 4.8, April 2020, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/). The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta). b Trends are from the SEER 21 areas (SEER 9 areas, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts). c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention. d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint. e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. g Data for American Indian/Alaska Native are based on the Purchased/Referred Care Delivery Area (PRCDA) counties. * The APC/AAPC is significantly different from zero (p<.05). - Joinpoint regression line analysis could not be performed on data series. JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPC d Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17 SEER 9 Delay-Adjusted Incidence a , 1975-2017 All Races 1975-97 0.2 1997-17 0.7* 0.7* 0.7* White 1975-97 0.3* 1997-17 0.9* 0.9* 0.9* Black 1975-17 0.3* 0.3* 0.3* SEER 21 Delay-Adjusted Incidence b , 2000-2017 All Races 2000-08 0.3 2008-11 3.3 2011-17 -0.1 1.0 -0.1 White 2000-08 0.5 2008-11 3.3 2011-17 0.0 1.1 0.0 White NH ef 2000-08 0.5 2008-11 3.6 2011-17 0.1 1.2 0.1 Black 2000-08 -1.1 2008-12 4.6 2012-17 -0.4 1.8 -0.4 Black NH ef 2000-08 -1.1 2008-12 4.6 2012-17 -0.2 1.9 -0.2 API e 2000-17 0.8* 0.8* 0.8* AI/AN eg 2000-17 1.3 1.3 1.3 Hispanic f 2000-17 0.7* 0.7* 0.7* U.S. Cancer Mortality c , 1975-2017 All Races 1975-80 0.6 1980-88 -0.6* 1988-91 0.7 1991-01 -0.5* 2001-13 -1.0* 2013-17 -2.4* -1.6* -2.4* White 1975-00 -0.3* 2000-13 -0.9* 2013-17 -2.2* -1.5* -2.2* Black 1975-93 0.6* 1993-17 -1.4* -1.4* -1.4* U.S. Cancer Mortality c , 2000-2017 All Races 2000-13 -1.0* 2013-17 -2.4* -1.6* -2.4* White 2000-13 -0.9* 2013-17 -2.2* -1.5* -2.2* White NH ef 2000-13 -0.9* 2013-17 -2.2* -1.5* -2.2* Black 2000-17 -1.6* -1.6* -1.6* Black NH ef 2000-17 -1.5* -1.5* -1.5* API e 2000-08 -0.7 2008-11 3.8 2011-15 -5.1* 2015-17 2.5 -0.6 -1.4 AI/AN eg 2000-17 -1.7* -1.7* -1.7* Hispanic f 2000-17 -0.9* -0.9* -0.9* Table 13.1 Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to Five Joinpoints, 2000-2017 With up to Three Joinpoints, Both Sexes by Race/Ethnicity

SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

  • Upload
    others

  • View
    4

  • Download
    0

Embed Size (px)

Citation preview

Page 1: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-97 02 1997-17 07 07 07

White 1975-97 03 1997-17 09 09 09

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-08 03 2008-11 33 2011-17 -01 10 -01

White 2000-08 05 2008-11 33 2011-17 00 11 00

White NHef 2000-08 05 2008-11 36 2011-17 01 12 01

Black 2000-08 -11 2008-12 46 2012-17 -04 18 -04

Black NHef 2000-08 -11 2008-12 46 2012-17 -02 19 -02

APIe 2000-17 08 08 08

AIANeg 2000-17 13 13 13

Hispanicf 2000-17 07 07 07

US Cancer Mortalityc 1975-2017

All Races 1975-80 06 1980-88 -06 1988-91 07 1991-01 -05 2001-13 -10 2013-17 -24 -16 -24

White 1975-00 -03 2000-13 -09 2013-17 -22 -15 -22

Black 1975-93 06 1993-17 -14 -14 -14

US Cancer Mortalityc 2000-2017

All Races 2000-13 -10 2013-17 -24 -16 -24

White 2000-13 -09 2013-17 -22 -15 -22

White NHef 2000-13 -09 2013-17 -22 -15 -22

Black 2000-17 -16 -16 -16

Black NHef 2000-17 -15 -15 -15

APIe 2000-08 -07 2008-11 38 2011-15 -51 2015-17 25 -06 -14

AIANeg 2000-17 -17 -17 -17

Hispanicf 2000-17 -09 -09 -09

Table 131

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Both Sexes by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-96 00 1996-17 06 06 06

White 1975-96 01 1996-17 07 07 07

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-07 01 2007-13 20 2013-17 -10 06 -10

White 2000-07 03 2007-13 20 2013-17 -09 07 -09

White NHef 2000-08 04 2008-11 32 2011-15 07 2015-17 -20 09 -06

Black 2000-17 08 08 08

Black NHef 2000-17 08 08 08

APIe 2000-17 08 08 08

AIANeg 2000-17 26 26 26

Hispanicf 2000-17 05 05 05

US Cancer Mortalityc 1975-2017

All Races 1975-96 -02 1996-12 -08 2012-17 -24 -17 -24

White 1975-01 -03 2001-13 -09 2013-17 -25 -16 -25

Black 1975-90 11 1990-08 -10 2008-17 -25 -25 -25

US Cancer Mortalityc 2000-2017

All Races 2000-13 -10 2013-17 -27 -17 -27

White 2000-13 -09 2013-17 -25 -16 -25

White NHef 2000-12 -08 2012-17 -22 -16 -22

Black 2000-17 -18 -18 -18

Black NHef 2000-17 -17 -17 -17

APIe 2000-17 -04 -04 -04

AIANeg 2000-17 -08 -08 -08

Hispanicf 2000-17 -10 -10 -10

Table 132

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-17 05 05 05

White 1975-17 06 06 06

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-08 03 2008-11 31 2011-17 -01 09 -01

White 2000-17 10 10 10

White NHef 2000-17 11 11 11

Black 2000-08 -10 2008-13 39 2013-17 -03 20 -03

Black NHef 2000-07 -15 2007-13 33 2013-17 02 19 02

APIe 2000-17 09 09 09

AIANeg 2000-17 02 02 02

Hispanicf 2000-17 08 08 08

US Cancer Mortalityc 1975-2017

All Races 1975-80 07 1980-00 -04 2000-17 -13 -13 -13

White 1975-00 -03 2000-17 -12 -12 -12

Black 1975-93 04 1993-17 -13 -13 -13

US Cancer Mortalityc 2000-2017

All Races 2000-17 -13 -13 -13

White 2000-17 -12 -12 -12

White NHef 2000-17 -13 -13 -13

Black 2000-17 -15 -15 -15

Black NHef 2000-17 -14 -14 -14

APIe 2000-11 07 2011-17 -43 -26 -43

AIANeg 2000-17 -27 -27 -27

Hispanicf 2000-17 -07 -07 -07

Table 133

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1398 1802 1083 1491 1929 1139 1157 1571 8802010 1487 1948 1136 1603 2095 1218 1142 1504 9242011 1518 1949 1173 1623 2076 1254 1291 1546 10872012 1505 1900 1193 1618 2027 1287 1247 1592 10162013 1501 1935 1157 1626 2076 1263 1223 1629 9212014 1522 1990 1152 1645 2130 1249 1191 1498 9772015 1485 1889 1152 1619 2060 1244 1147 1372 10052016 1512 1971 1137 1646 2139 1232 1315 1703 10462017 1525 1959 1172 1632 2080 1258 1295 1683 1028

Table 134Leukemia

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1359 1780 1044 1431 1880 1096 1125 1455 8981975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1388 1789 1075 1478 1913 1130 1149 1561 8742010 1466 1920 1120 1575 2058 1197 1127 1485 9122011 1486 1907 1148 1582 2023 1222 1265 1516 10652012 1463 1846 1160 1563 1958 1244 1214 1548 9902013 1448 1865 1117 1558 1988 1210 1181 1574 8892014 1458 1904 1104 1562 2022 1188 1142 1437 9382015 1404 1784 1090 1515 1927 1164 1085 1294 9532016 1409 1834 1062 1516 1968 1135 1221 1581 9702017 1389 1782 1068 1465 1866 1130 1169 1514 931

Table 135Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 2: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-96 00 1996-17 06 06 06

White 1975-96 01 1996-17 07 07 07

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-07 01 2007-13 20 2013-17 -10 06 -10

White 2000-07 03 2007-13 20 2013-17 -09 07 -09

White NHef 2000-08 04 2008-11 32 2011-15 07 2015-17 -20 09 -06

Black 2000-17 08 08 08

Black NHef 2000-17 08 08 08

APIe 2000-17 08 08 08

AIANeg 2000-17 26 26 26

Hispanicf 2000-17 05 05 05

US Cancer Mortalityc 1975-2017

All Races 1975-96 -02 1996-12 -08 2012-17 -24 -17 -24

White 1975-01 -03 2001-13 -09 2013-17 -25 -16 -25

Black 1975-90 11 1990-08 -10 2008-17 -25 -25 -25

US Cancer Mortalityc 2000-2017

All Races 2000-13 -10 2013-17 -27 -17 -27

White 2000-13 -09 2013-17 -25 -16 -25

White NHef 2000-12 -08 2012-17 -22 -16 -22

Black 2000-17 -18 -18 -18

Black NHef 2000-17 -17 -17 -17

APIe 2000-17 -04 -04 -04

AIANeg 2000-17 -08 -08 -08

Hispanicf 2000-17 -10 -10 -10

Table 132

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-17 05 05 05

White 1975-17 06 06 06

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-08 03 2008-11 31 2011-17 -01 09 -01

White 2000-17 10 10 10

White NHef 2000-17 11 11 11

Black 2000-08 -10 2008-13 39 2013-17 -03 20 -03

Black NHef 2000-07 -15 2007-13 33 2013-17 02 19 02

APIe 2000-17 09 09 09

AIANeg 2000-17 02 02 02

Hispanicf 2000-17 08 08 08

US Cancer Mortalityc 1975-2017

All Races 1975-80 07 1980-00 -04 2000-17 -13 -13 -13

White 1975-00 -03 2000-17 -12 -12 -12

Black 1975-93 04 1993-17 -13 -13 -13

US Cancer Mortalityc 2000-2017

All Races 2000-17 -13 -13 -13

White 2000-17 -12 -12 -12

White NHef 2000-17 -13 -13 -13

Black 2000-17 -15 -15 -15

Black NHef 2000-17 -14 -14 -14

APIe 2000-11 07 2011-17 -43 -26 -43

AIANeg 2000-17 -27 -27 -27

Hispanicf 2000-17 -07 -07 -07

Table 133

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1398 1802 1083 1491 1929 1139 1157 1571 8802010 1487 1948 1136 1603 2095 1218 1142 1504 9242011 1518 1949 1173 1623 2076 1254 1291 1546 10872012 1505 1900 1193 1618 2027 1287 1247 1592 10162013 1501 1935 1157 1626 2076 1263 1223 1629 9212014 1522 1990 1152 1645 2130 1249 1191 1498 9772015 1485 1889 1152 1619 2060 1244 1147 1372 10052016 1512 1971 1137 1646 2139 1232 1315 1703 10462017 1525 1959 1172 1632 2080 1258 1295 1683 1028

Table 134Leukemia

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1359 1780 1044 1431 1880 1096 1125 1455 8981975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1388 1789 1075 1478 1913 1130 1149 1561 8742010 1466 1920 1120 1575 2058 1197 1127 1485 9122011 1486 1907 1148 1582 2023 1222 1265 1516 10652012 1463 1846 1160 1563 1958 1244 1214 1548 9902013 1448 1865 1117 1558 1988 1210 1181 1574 8892014 1458 1904 1104 1562 2022 1188 1142 1437 9382015 1404 1784 1090 1515 1927 1164 1085 1294 9532016 1409 1834 1062 1516 1968 1135 1221 1581 9702017 1389 1782 1068 1465 1866 1130 1169 1514 931

Table 135Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 3: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-17 05 05 05

White 1975-17 06 06 06

Black 1975-17 03 03 03

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-08 03 2008-11 31 2011-17 -01 09 -01

White 2000-17 10 10 10

White NHef 2000-17 11 11 11

Black 2000-08 -10 2008-13 39 2013-17 -03 20 -03

Black NHef 2000-07 -15 2007-13 33 2013-17 02 19 02

APIe 2000-17 09 09 09

AIANeg 2000-17 02 02 02

Hispanicf 2000-17 08 08 08

US Cancer Mortalityc 1975-2017

All Races 1975-80 07 1980-00 -04 2000-17 -13 -13 -13

White 1975-00 -03 2000-17 -12 -12 -12

Black 1975-93 04 1993-17 -13 -13 -13

US Cancer Mortalityc 2000-2017

All Races 2000-17 -13 -13 -13

White 2000-17 -12 -12 -12

White NHef 2000-17 -13 -13 -13

Black 2000-17 -15 -15 -15

Black NHef 2000-17 -14 -14 -14

APIe 2000-11 07 2011-17 -43 -26 -43

AIANeg 2000-17 -27 -27 -27

Hispanicf 2000-17 -07 -07 -07

Table 133

Leukemia

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1398 1802 1083 1491 1929 1139 1157 1571 8802010 1487 1948 1136 1603 2095 1218 1142 1504 9242011 1518 1949 1173 1623 2076 1254 1291 1546 10872012 1505 1900 1193 1618 2027 1287 1247 1592 10162013 1501 1935 1157 1626 2076 1263 1223 1629 9212014 1522 1990 1152 1645 2130 1249 1191 1498 9772015 1485 1889 1152 1619 2060 1244 1147 1372 10052016 1512 1971 1137 1646 2139 1232 1315 1703 10462017 1525 1959 1172 1632 2080 1258 1295 1683 1028

Table 134Leukemia

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1359 1780 1044 1431 1880 1096 1125 1455 8981975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1388 1789 1075 1478 1913 1130 1149 1561 8742010 1466 1920 1120 1575 2058 1197 1127 1485 9122011 1486 1907 1148 1582 2023 1222 1265 1516 10652012 1463 1846 1160 1563 1958 1244 1214 1548 9902013 1448 1865 1117 1558 1988 1210 1181 1574 8892014 1458 1904 1104 1562 2022 1188 1142 1437 9382015 1404 1784 1090 1515 1927 1164 1085 1294 9532016 1409 1834 1062 1516 1968 1135 1221 1581 9702017 1389 1782 1068 1465 1866 1130 1169 1514 931

Table 135Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 4: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1398 1802 1083 1491 1929 1139 1157 1571 8802010 1487 1948 1136 1603 2095 1218 1142 1504 9242011 1518 1949 1173 1623 2076 1254 1291 1546 10872012 1505 1900 1193 1618 2027 1287 1247 1592 10162013 1501 1935 1157 1626 2076 1263 1223 1629 9212014 1522 1990 1152 1645 2130 1249 1191 1498 9772015 1485 1889 1152 1619 2060 1244 1147 1372 10052016 1512 1971 1137 1646 2139 1232 1315 1703 10462017 1525 1959 1172 1632 2080 1258 1295 1683 1028

Table 134Leukemia

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1359 1780 1044 1431 1880 1096 1125 1455 8981975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1388 1789 1075 1478 1913 1130 1149 1561 8742010 1466 1920 1120 1575 2058 1197 1127 1485 9122011 1486 1907 1148 1582 2023 1222 1265 1516 10652012 1463 1846 1160 1563 1958 1244 1214 1548 9902013 1448 1865 1117 1558 1988 1210 1181 1574 8892014 1458 1904 1104 1562 2022 1188 1142 1437 9382015 1404 1784 1090 1515 1927 1164 1085 1294 9532016 1409 1834 1062 1516 1968 1135 1221 1581 9702017 1389 1782 1068 1465 1866 1130 1169 1514 931

Table 135Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 5: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1359 1780 1044 1431 1880 1096 1125 1455 8981975-1979 1289 1714 997 1334 1789 1024 1052 1376 8301980 1293 1738 985 1328 1792 1011 1224 1611 9571981 1238 1647 965 1265 1703 982 1227 1447 10371982 1315 1823 971 1350 1877 995 1075 1516 7911983 1314 1780 991 1348 1842 1007 1248 1595 10061984 1301 1711 1012 1347 1797 1036 1068 1187 9611985 1339 1778 1039 1376 1832 1066 1232 1703 9301986 1284 1754 951 1339 1839 992 1023 1320 8091987 1338 1778 1033 1383 1850 1064 1257 1760 9261988 1299 1753 973 1345 1831 1003 1155 1403 9421989 1348 1771 1049 1403 1838 1102 1126 1580 8111990 1293 1736 981 1356 1830 1028 1134 1478 8891991 1308 1682 1025 1371 1778 1060 1081 1209 9981992 1307 1757 982 1366 1873 1004 1068 1391 8421993 1310 1713 1007 1368 1807 1036 1168 1529 9141994 1313 1706 1023 1384 1801 1078 986 1271 7781995 1363 1780 1053 1453 1893 1126 997 1369 7421996 1321 1706 1045 1382 1788 1091 1077 1400 8731997 1327 1770 1004 1411 1881 1070 1067 1423 8291998 1328 1727 1034 1410 1820 1105 1002 1444 7271999 1290 1725 968 1356 1808 1017 1063 1423 8282000 1383 1794 1075 1453 1890 1125 1199 1405 10452001 1451 1887 1121 1548 2000 1204 1200 1460 10202002 1372 1813 1038 1482 1953 1123 914 1207 7092003 1380 1809 1054 1462 1927 1108 1155 1515 8942004 1408 1832 1086 1484 1922 1142 1306 1784 10042005 1402 1834 1069 1496 1981 1115 1162 1325 10492006 1410 1764 1145 1515 1876 1245 1137 1546 8532007 1369 1792 1048 1482 1936 1130 996 1363 7732008 1424 1857 1083 1519 1982 1149 1119 1523 8252009 1388 1789 1075 1478 1913 1130 1149 1561 8742010 1466 1920 1120 1575 2058 1197 1127 1485 9122011 1486 1907 1148 1582 2023 1222 1265 1516 10652012 1463 1846 1160 1563 1958 1244 1214 1548 9902013 1448 1865 1117 1558 1988 1210 1181 1574 8892014 1458 1904 1104 1562 2022 1188 1142 1437 9382015 1404 1784 1090 1515 1927 1164 1085 1294 9532016 1409 1834 1062 1516 1968 1135 1221 1581 9702017 1389 1782 1068 1465 1866 1130 1169 1514 931

Table 135Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 6: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 140 160 121 148 170 127 087 099 0761975-1979 103 122 086 108 129 090 054 059 0491980 112 140 088 116 147 090 073 - -1981 124 131 118 130 139 123 095 - -1982 123 150 099 130 156 105 - - -1983 129 152 108 139 164 118 080 - -1984 132 148 120 134 149 124 092 - -1985 130 155 109 135 162 112 - - -1986 130 167 096 138 182 096 077 - -1987 132 148 119 136 154 121 089 - 1151988 140 179 107 145 185 112 098 - -1989 162 182 143 169 190 149 103 - -1990 142 176 116 152 185 129 057 - -1991 138 172 105 151 194 109 086 - -1992 135 159 114 140 173 109 091 - -1993 126 141 109 138 157 115 082 - -1994 119 148 093 128 159 101 068 - -1995 150 180 121 161 187 135 098 132 -1996 139 156 121 147 165 128 085 - -1997 133 151 116 144 160 128 079 098 -1998 146 161 131 157 169 144 093 116 -1999 131 149 114 140 156 124 068 - -2000 140 150 130 152 161 145 087 - -2001 146 166 126 158 182 134 070 - -2002 150 179 120 165 200 129 062 - -2003 143 166 122 147 170 127 078 097 -2004 156 171 140 168 196 139 112 - 1432005 158 188 129 166 194 138 097 118 -2006 145 163 128 151 164 139 097 142 -2007 152 167 138 160 172 150 095 106 -2008 150 185 115 168 203 132 091 132 -2009 147 161 135 157 174 141 096 108 0852010 146 155 136 158 164 152 097 110 0852011 178 189 167 194 200 189 133 164 1012012 148 153 143 161 164 159 112 145 0892013 162 179 145 175 192 158 097 132 -2014 160 176 144 169 193 146 087 - 1062015 149 173 126 158 181 134 081 100 -2016 169 189 149 174 204 144 107 122 0922017 164 186 144 176 203 150 098 105 091

Table 136Acute Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 7: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 492 681 350 536 743 382 385 542 2771975-1979 432 600 317 454 635 332 381 535 2781980 452 631 333 469 655 345 457 706 2991981 427 630 290 447 663 306 382 541 2471982 430 614 301 450 639 318 377 665 -1983 445 640 313 467 678 325 421 611 3031984 443 630 312 472 682 329 345 446 2651985 449 621 331 480 663 354 411 615 2871986 450 633 324 487 685 354 279 418 -1987 466 682 307 496 727 328 403 614 2451988 455 646 315 477 688 327 443 532 3531989 470 645 347 502 693 368 391 515 3041990 461 631 342 492 678 363 451 613 3431991 460 620 343 500 681 364 340 375 3151992 463 675 316 506 745 343 321 496 2081993 446 616 317 474 657 336 452 679 2891994 463 615 348 508 674 385 319 413 2321995 456 644 320 499 702 352 339 534 2061996 474 638 356 519 692 394 352 536 2261997 452 611 331 494 666 364 357 518 2521998 427 600 301 472 659 335 285 373 2291999 419 609 277 455 658 301 387 600 2602000 470 659 327 521 734 355 347 450 2782001 536 742 381 592 818 422 395 489 3282002 515 725 357 577 809 401 319 453 2202003 541 748 384 597 832 419 439 621 3122004 561 769 403 613 821 453 501 816 2892005 548 779 370 610 879 399 413 506 3532006 587 774 448 651 849 502 465 683 3222007 546 757 384 619 849 438 307 465 2232008 561 753 414 627 829 470 400 607 2482009 552 760 389 615 846 428 420 604 3052010 569 791 399 635 872 448 384 539 2892011 564 759 407 623 836 449 450 556 3712012 539 720 394 602 794 445 381 503 3022013 528 729 369 592 811 415 439 657 2772014 541 765 361 610 848 412 383 606 2272015 521 699 371 591 782 426 345 471 2562016 489 677 335 556 761 381 392 532 2932017 502 670 364 549 721 403 376 498 285

Table 137Chronic Lymphocytic Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 8: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 369 458 306 375 467 311 328 392 2861975-1979 343 425 288 351 438 293 261 297 2341980 314 410 243 317 411 249 288 328 2531981 317 399 265 321 411 268 315 322 3021982 342 479 260 347 490 263 250 322 2091983 321 422 253 317 428 241 293 302 2921984 330 406 273 335 417 277 235 210 2441985 333 415 287 325 402 284 378 506 2991986 300 391 240 295 385 238 321 404 2681987 302 397 247 303 400 247 305 473 2121988 303 379 252 308 387 257 279 314 2491989 320 401 262 330 404 279 222 379 -1990 304 391 243 312 407 246 249 289 2191991 333 393 288 338 390 298 334 453 2591992 322 385 276 328 403 275 305 299 3051993 345 432 285 352 446 285 248 262 2551994 346 414 302 348 424 297 294 324 2771995 366 417 331 381 432 345 262 262 2731996 347 433 291 346 429 294 321 405 2731997 353 461 277 366 482 285 302 383 2551998 393 494 321 406 506 332 305 464 2111999 373 451 318 385 463 330 303 345 2762000 405 495 341 404 495 339 441 488 4012001 406 495 340 420 500 361 345 408 3002002 363 458 298 378 478 311 291 331 2672003 360 449 296 367 460 302 333 352 2962004 342 415 293 351 423 300 339 431 3012005 359 426 317 365 438 319 349 347 3582006 354 411 315 367 422 327 284 334 2572007 355 438 298 366 448 309 338 445 2722008 383 471 319 387 488 308 309 378 2792009 363 442 307 376 465 309 313 398 2552010 424 539 341 444 568 350 336 454 2622011 421 514 348 426 518 352 417 452 3912012 459 562 378 469 573 388 385 449 3422013 449 544 381 467 556 403 419 508 3522014 441 534 373 462 551 398 379 453 3182015 427 518 359 444 541 369 370 415 3472016 438 550 351 453 567 365 406 491 3542017 432 536 353 433 531 359 421 531 346

Table 138Acute Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 9: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 182 240 139 185 243 141 184 241 1441975-1979 183 244 141 184 247 141 180 239 1361980 170 206 146 173 210 151 148 - -1981 164 197 141 159 190 139 238 300 1811982 168 216 135 165 219 131 175 - 1791983 169 223 133 164 215 132 251 344 1851984 168 240 118 163 241 110 258 261 2591985 197 276 143 200 280 147 206 289 -1986 168 219 129 171 225 131 154 - -1987 188 233 158 191 239 158 214 288 -1988 191 254 150 192 259 149 208 288 -1989 170 222 135 168 218 135 221 312 -1990 176 247 124 175 250 120 263 366 1951991 188 244 147 191 255 146 156 - 1751992 176 216 147 180 222 149 149 173 -1993 192 253 148 195 252 155 228 356 -1994 188 250 142 191 250 150 170 257 -1995 190 256 138 196 269 139 159 209 -1996 181 245 135 180 251 128 206 254 1831997 187 268 130 194 274 137 167 253 -1998 166 195 143 173 198 154 161 231 1201999 181 250 129 178 245 128 172 230 1262000 179 234 136 180 233 140 161 180 1382001 180 236 138 185 237 146 197 283 1362002 164 208 132 167 212 136 113 - -2003 166 225 119 177 237 128 144 224 -2004 180 256 122 187 267 124 151 206 1112005 170 226 126 178 236 131 174 237 1342006 184 240 141 194 251 151 158 217 1112007 172 233 123 182 251 124 143 183 1192008 186 239 143 186 232 151 189 267 1212009 180 239 133 179 232 138 192 295 1282010 189 252 140 190 256 137 191 212 1832011 196 257 146 207 273 150 166 195 1392012 194 236 162 198 240 166 215 287 1622013 193 262 139 199 268 142 169 227 1372014 198 262 146 197 256 147 205 196 2132015 189 235 149 200 247 158 181 215 1572016 211 272 163 222 275 178 218 311 1582017 195 255 144 203 263 151 195 272 142

Table 139Chronic Myeloid Leukemia

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 10: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 748 1002 571 769 1032 586 651 857 5171975-1979 812 1092 624 829 1120 634 678 880 5361980 836 1121 646 854 1151 656 705 909 5671981 810 1089 624 824 1116 631 711 892 5861982 819 1104 631 833 1129 639 714 936 5671983 811 1093 626 824 1119 632 722 921 5901984 808 1068 637 823 1091 647 708 916 5691985 807 1077 631 823 1097 644 708 962 5421986 796 1071 616 810 1097 623 725 926 5911987 780 1031 614 791 1050 620 724 941 5851988 783 1060 600 795 1079 608 724 983 5581989 795 1062 615 807 1075 626 736 1034 5451990 798 1071 618 810 1090 626 744 996 5831991 799 1050 632 812 1064 644 745 1005 5801992 796 1071 613 811 1094 624 716 941 5681993 793 1066 609 804 1084 616 736 976 5771994 785 1057 603 800 1078 613 712 959 5541995 790 1080 598 804 1103 605 717 975 5531996 784 1053 605 797 1071 613 746 1009 5901997 771 1042 589 789 1068 601 683 923 5291998 758 1011 582 772 1031 591 704 937 5551999 768 1022 596 787 1047 609 674 878 5432000 769 1028 591 789 1054 605 671 907 5272001 764 1019 588 783 1046 602 674 880 5412002 754 1018 573 775 1046 585 673 891 5382003 745 1002 563 768 1037 576 654 847 5302004 729 981 552 747 1004 564 677 894 5392005 726 982 546 750 1014 563 607 811 4782006 723 970 546 748 997 566 627 884 4702007 708 954 533 730 986 546 619 807 5052008 709 954 533 732 983 549 627 865 4782009 706 953 525 731 986 541 605 814 4712010 691 926 520 716 958 537 575 746 4602011 695 928 525 719 961 539 600 774 4852012 683 922 507 708 957 522 577 756 4622013 676 910 503 703 943 523 568 771 4372014 662 883 497 691 921 516 548 718 4372015 629 847 464 656 882 482 520 684 4152016 627 829 475 653 865 492 543 687 4492017 619 823 464 647 860 482 515 646 424

Table 1310Leukemia

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 11: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 141 181 110 150 192 116 108 136 89Under 65 71 84 59 75 89 62 59 67 5165 and over 626 850 461 670 907 492 452 613 353

All ages (WHO world std)c 110 137 87 117 146 91 85 104 71

Age-Specific Rates 2013-2017lt1 45 42 48 46 44 47 33 - 411-4 90 93 87 97 103 92 49 43 555-9 42 47 38 47 52 41 22 22 2210-14 34 39 28 35 40 31 26 32 2015-19 32 39 25 34 43 25 23 26 1920-24 29 33 24 30 35 24 24 23 2525-29 30 34 26 31 35 27 24 25 2230-34 37 41 32 37 43 32 33 33 3335-39 44 50 37 46 52 39 41 47 3640-44 60 70 50 63 74 51 56 64 4945-49 86 98 74 88 99 77 86 99 7550-54 129 159 101 136 166 106 111 136 9055-59 183 223 144 193 235 152 154 191 12260-64 277 352 208 293 373 217 230 277 19265-69 399 520 292 425 552 310 319 409 25070-74 550 727 400 586 771 427 406 536 31475-79 710 957 518 761 1018 555 530 714 41280-84 842 1174 610 905 1262 651 586 823 45385+ 886 1271 684 952 1367 732 550 807 442

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 64 86 48 67 89 50 54 70 43Under 65 18 21 15 18 21 15 19 23 1665 and over 385 532 279 404 558 292 293 397 230

All ages (WHO world std)c 36 47 27 37 48 28 33 41 26

Age-Specific Rates 2013-2017lt1 05 04 06 05 05 05 06 - -1-4 07 07 06 07 07 06 06 07 065-9 04 05 04 05 06 04 04 03 0410-14 05 06 05 06 06 05 05 06 0415-19 07 09 06 08 09 06 05 07 0420-24 08 11 06 09 11 06 08 10 0625-29 09 10 07 09 11 07 08 10 0730-34 10 11 08 10 12 08 11 12 1035-39 12 13 11 12 13 10 13 15 1240-44 15 17 14 16 17 15 17 19 1645-49 22 24 20 22 24 20 26 30 2350-54 34 40 28 34 41 27 38 43 3455-59 54 66 43 55 67 43 60 74 4860-64 91 115 68 92 118 69 99 124 7865-69 154 207 107 160 215 110 145 196 10670-74 263 353 186 275 367 194 227 301 17375-79 420 575 295 441 603 310 328 448 25080-84 605 846 433 639 892 454 442 589 35985+ 828 1181 641 876 1247 677 523 729 437

Table 1311Leukemia

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 12: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 17 20 15 19 22 16 10 11 09Under 65 18 20 15 19 22 16 10 11 0965 and over 16 19 14 17 20 15 09 10 09

All ages (WHO world std)b 19 21 16 21 23 18 10 11 10

Age-Specific Rates 2013-2017lt1 17 16 19 18 16 20 - - -1-4 76 79 74 84 88 79 36 31 415-9 36 39 33 40 45 36 18 17 1910-14 23 27 19 25 29 22 13 18 0915-19 18 24 12 21 28 13 08 11 -20-24 11 14 07 11 15 07 06 06 0525-29 08 10 06 09 11 07 04 05 -30-34 07 08 06 08 09 06 03 - -35-39 08 10 06 08 10 06 05 - -40-44 08 10 06 09 11 06 06 07 -45-49 09 09 09 10 10 10 05 - -50-54 09 10 09 10 10 09 09 11 0755-59 11 12 11 12 13 11 09 09 0960-64 13 15 11 14 15 12 09 13 -65-69 15 17 13 16 18 14 09 - -70-74 16 19 14 18 21 15 - - -75-79 18 21 15 19 22 17 13 - -80-84 17 21 14 18 23 14 - - -85+ 15 16 15 17 18 16 - - -

Chronic Lymphocytic LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 50 68 35 54 73 39 33 48 24Under 65 17 22 12 19 24 13 12 17 0865 and over 275 380 197 300 411 216 180 259 130

All ages (WHO world std)b 35 47 25 38 51 27 24 34 17

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 01 - - 01 - - - - -30-34 01 02 01 01 02 - - - -35-39 04 05 03 04 05 03 03 - -40-44 10 13 07 10 13 07 09 12 0645-49 23 28 18 25 29 20 18 25 1250-54 49 66 33 54 71 37 33 48 2055-59 81 105 59 90 115 65 53 73 3660-64 129 174 88 139 186 95 93 127 6565-69 187 250 131 203 269 144 129 178 9270-74 244 332 170 264 355 185 175 243 12875-79 310 424 220 338 457 243 208 300 14980-84 353 501 251 388 545 276 219 342 15085+ 384 550 298 422 604 326 206 305 164

Table 1312Lymphocytic Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 13: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 43 52 36 44 54 37 37 44 33Under 65 20 21 19 20 21 19 20 20 2065 and over 201 268 152 212 282 160 154 205 123

All ages (WHO world std)b 32 38 28 33 40 28 29 33 26

Age-Specific Rates 2013-2017lt1 16 15 18 17 15 18 - - -1-4 10 10 10 10 10 10 10 09 125-9 04 05 04 04 05 04 03 - -10-14 08 09 06 07 08 06 09 10 0815-19 09 09 09 09 09 09 09 09 0920-24 11 11 11 11 11 11 12 12 1225-29 12 12 12 11 11 11 11 10 1130-34 14 14 14 14 15 13 15 12 1835-39 16 15 16 15 15 16 18 18 1840-44 21 21 22 21 21 22 21 21 2245-49 26 26 26 26 26 25 30 29 3050-54 37 40 33 38 42 34 34 36 3255-59 49 54 43 48 54 43 52 61 4460-64 79 91 67 83 97 69 70 74 6665-69 120 147 95 127 157 99 98 116 8570-74 184 237 139 194 248 147 146 194 11275-79 233 307 176 246 321 186 184 238 14980-84 284 391 209 300 416 218 210 298 16085+ 263 388 198 277 410 207 180 259 146

Chronic Myeloid LeukemiaAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 19 25 15 20 26 15 18 22 15Under 65 11 13 09 11 13 09 11 13 1065 and over 78 107 56 82 112 59 62 84 49

All ages (WHO world std)b 15 19 12 15 19 12 14 17 12

Age-Specific Rates 2013-2017lt1 05 06 - 05 07 - - - -1-4 01 01 - 01 - - - - -5-9 01 - 01 01 - - - - -10-14 01 02 01 01 02 - - - -15-19 03 04 02 03 03 02 04 - -20-24 05 06 04 05 06 04 04 - -25-29 07 09 06 08 09 06 06 07 0530-34 11 13 09 11 12 10 10 12 0835-39 11 13 09 12 13 10 11 14 0840-44 14 17 10 14 18 11 13 17 1045-49 18 21 16 17 20 15 26 28 2450-54 22 26 17 22 26 17 25 29 2155-59 26 31 23 27 31 23 27 31 2460-64 37 46 28 37 47 28 37 42 3365-69 49 65 34 49 66 33 52 64 4270-74 66 85 50 69 89 52 51 66 4075-79 93 128 65 98 135 69 72 100 5480-84 108 152 78 115 160 82 77 104 6285+ 107 158 80 112 166 83 75 116 59

Table 1313Myeloid Leukemia

SEER Incidencea Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 14: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 14 - - - - -1970-1973a - - - 22 - - - - -1975-1977b 342 330 356 346 335 358 334 304 3671978-1980b 360 350 374 367 357 381 282 273 2931981-1983b 373 369 378 381 377 385 339 334 3431984-1986b 405 401 411 416 413 420 327 315 3411987-1989b 429 440 413 439 455 418 350 327 3781990-1992b 452 446 460 465 463 468 357 305 4131993-1995b 476 485 464 487 496 475 413 416 4091996-1998b 484 487 481 498 498 499 386 390 3801999-2001b 510 520 497 521 531 508 439 451 4252002-2004b 583 584 581 591 594 588 539 545 5312005-2009b 627 640 609 639 649 624 560 597 5122010-2016b 664e 676e 648e 673e 683e 659e 625e 642e 607e

5-Year Period Survival (Percent)cd

2016 643 652 631 645 648 640 606 641 567

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 768 765 773 778 769 789 694 693 695Ages 45-54 733 749 710 743 756 722 669 696 632Ages 55-64 704 712 692 717 719 714 596 642 531Ages 65-74 621 623 618 625 622 630 571 598 534Ages 75+ 430 428 431 435 429 443 359 403 325Ages lt65 738 741 733 748 747 749 656 676 631Ages 65+ 519 528 508 523 527 519 475 524 429

Table 1314Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 15: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 406 369 456 408 374 457 335e - -1987-1989a 544 537 552 550 548 553 447e 420e 471e1990-1992a 580 545 631 577 549 620 571e 504e 633e1993-1995a 602 578 635 598 578 626 532e 459e 638e1996-1998a 655 644 669 664 643 691 556e 591e 502e1999-2001a 635 634 637 648 652 643 566e 503e 630e2002-2004a 673 662 688 676 666 690 645e 594e 697e2005-2009a 699 690 712 708 693 728 626 676 530e2010-2016a 721d 726d 716d 719d 729d 708d 664d 640 691

5-Year Period Survival (Percent)bc2016 690 681 701 684 668 706 675 676 670

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 807 794 824 806 789 830 771 760 786Ages 45-54 390 377 408 372 369 380 349e - -Ages 55-64 315 325 305 323 330 314 221e 282e 137eAges 65-74 241 193 286 241 180 300 - - -Ages 75+ 111 100 120 111 90 129 - - -Ages lt65 735 728 745 734 723 748 685 678 693Ages 65+ 183 155 207 185 144 224 128e - 116e

Chronic Lymphocytic Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 671 647 704 679 653 713 569e 551e 590e1987-1989a 727 726 727 738 740 735 581 555e 615e1990-1992a 741 718 773 753 732 784 522 434e 609e1993-1995a 772 771 773 784 782 786 633 640e 621e1996-1998a 756 740 777 767 753 786 581 515e 660e1999-2001a 787 782 794 795 790 805 668 655e 671e2002-2004a 840 831 851 844 836 856 770 742e 807e2005-2009a 863 863 864 866 866 868 843 857 8182010-2016a 886d 886d 888d 890d 886d 896d 812d 832d 785

5-Year Period Survival (Percent)bc2016 870 868 873 866 859 875 824 867 765

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 937 923 958 945 936 954 878e 845e -Ages 45-54 940 941 937 945 943 948 856 883 803eAges 55-64 927 921 938 930 921 948 849 864 825Ages 65-74 886 870 914 886 864 923 827 845 793Ages 75+ 743 733 753 739 724 753 640 676e 608eAges lt65 931 927 939 935 928 949 854 870 827Ages 65+ 814 808 822 811 800 825 749 791 702

Table 1315Lymphocytic Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 16: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)e The standard error is between 5 and 10 percentage pointsf The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Acute Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 62 55 69 58 54 62 101 82 1171987-1989a 115 92 141 113 97 132 92 44 157e1990-1992a 138 126 152 135 122 150 135 129 1391993-1995a 161 150 173 153 142 166 215 206e 2201996-1998a 170 159 184 157 145 172 221 252 1821999-2001a 192 188 197 187 176 199 193 248 1422002-2004a 234 209 264 232 208 260 253 265 2402005-2009a 255 250 262 249 243 256 255 223 2812010-2016a 298d 289d 309d 293d 280d 308d 305d 293d 316d

5-Year Period Survival (Percent)bc2016 293 288 299 288 280 295 292 286 297

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 615 604 627 632 618 646 538 511 561Ages 45-54 453 444 464 466 455 479 364 358 372Ages 55-64 304 281 335 315 285 356 191 212 162Ages 65-74 148 145 153 155 155 155 95 45 141Ages 75+ 32 38 24 32 38 25 26 55 09Ages lt65 475 452 502 484 457 516 402 384 420Ages 65+ 82 88 76 85 92 77 60 47 71

Chronic Myeloid Leukemia5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 218 193 251 205 184 234 277e 216e 355e1987-1989a 303 306 298 301 310 290 333e 281e 413e1990-1992a 306 296 319 301 300 303 349e 255e 449e1993-1995a 355 352 359 351 350 352 356e 328e 402e1996-1998a 372 377 364 381 376 385 310 304e 314e1999-2001a 473 459 493 459 441 483 495e 496e 493e2002-2004a 544 531 562 528 515 544 629e 633e 619e2005-2009a 634 634 635 625 622 630 614 633e 581e2010-2016a 717d 701d 737d 707d 694d 723d 783d 757d 807d

5-Year Period Survival (Percent)bc2016 705 691 726 691 675 715 736 716 757

5-Year Relative Survival (Percent) 2010-2016bAge at DiagnosisAges lt45 901 893 913 914 908 923 821 803 846Ages 45-54 892 872 921 886 866 915 903 877 925Ages 55-64 777 762 800 781 754 819 691 762e 608eAges 65-74 613 584 652 611 579 659 575e 535e 613eAges 75+ 367 336 393 367 340 389 354e 346f 351eAges lt65 858 845 876 860 844 884 808 815 797Ages 65+ 486 468 509 482 464 506 488 474e 502e

Table 1316Myeloid Leukemia

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 17: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 607 626 648 668 682 682 678 667 660 669 706 722 734 750 741 765 770 767 774 783 796 792 790 792 810 7912-year 501 525 552 575 589 599 597 581 585 590 631 650 663 677 684 707 707 704 710 727 735 728 734 738 7553-year 438 465 496 529 543 554 550 541 548 551 591 620 624 642 649 675 676 666 686 696 706 695 703 7054-year 389 417 455 491 507 519 510 504 517 520 568 597 596 619 628 648 654 641 661 679 687 678 6765-year 346 376 423 461 481 487 483 482 485 499 544 577 575 596 610 627 638 621 637 663 669 6616-year 314 350 398 436 457 465 458 462 463 486 524 561 557 572 594 608 623 606 615 652 6607-year 291 325 372 410 443 451 439 447 445 473 511 545 538 561 582 593 616 588 604 6418-year 270 304 350 388 417 439 433 432 430 458 497 536 520 547 563 574 605 578 5869-year 250 285 330 373 406 421 419 422 422 449 483 520 509 531 547 562 595 56810-year 237 269 316 361 392 407 407 411 407 439 471 506 491 515 534 546 58511-year 224 257 299 347 378 398 389 398 393 427 460 493 475 499 529 53512-year 212 246 288 336 371 387 378 391 384 421 450 485 463 493 52313-year 205 236 280 327 367 383 371 381 373 405 442 468 457 48014-year 198 229 273 319 356 370 369 371 368 393 434 459 44915-year 192 223 267 314 353 362 364 360 361 385 424 44916-year 185 214 261 307 350 359 363 351 355 377 41917-year 181 207 256 300 340 355 353 347 348 37418-year 177 201 253 295 330 351 347 345 34619-year 172 195 248 292 326 343 345 34520-year 167 191 245 287 320 338 336

Table 1317Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 18: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 603 628 655 678 693 697 687 666 669 688 727 730 744 766 760 770 781 776 790 794 808 799 802 813 820 7982-year 496 524 561 583 604 616 610 586 592 608 648 652 669 686 701 708 719 716 728 742 749 735 751 757 7663-year 427 460 499 533 556 573 553 546 553 572 610 625 628 653 665 675 690 679 701 716 722 702 718 7244-year 379 412 460 495 517 536 507 506 520 538 581 598 602 627 650 649 668 651 680 693 700 682 6895-year 334 370 429 462 482 496 479 485 481 523 553 571 578 601 629 627 653 633 659 677 687 6646-year 303 343 403 436 452 471 459 462 462 508 529 555 557 575 609 604 636 616 633 666 6747-year 277 318 374 409 440 457 439 444 441 498 515 531 536 565 596 591 627 596 621 6598-year 254 294 354 386 418 446 431 431 424 478 500 521 514 550 572 565 616 585 6049-year 233 274 333 371 405 424 421 420 416 463 486 508 503 528 553 549 606 57110-year 219 260 317 359 385 408 413 410 402 454 471 491 482 511 540 528 59711-year 205 249 302 347 377 398 393 393 385 444 461 475 465 497 533 51512-year 194 243 291 335 371 391 381 384 376 437 452 469 457 492 52713-year 186 234 283 325 367 390 374 370 364 419 441 457 450 48014-year 179 227 277 316 357 378 370 358 359 410 433 449 44615-year 175 221 270 310 352 372 365 350 353 399 422 43716-year 168 213 263 304 347 370 362 342 348 388 41717-year 164 204 260 297 339 367 349 336 346 38718-year 160 199 257 291 326 365 345 332 34419-year 155 192 254 289 322 356 342 33220-year 147 187 249 285 317 348 336

Table 1318Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 19: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 612 623 638 654 666 663 665 668 646 644 676 711 720 728 715 758 755 754 751 767 780 783 773 764 796 7792-year 509 526 541 564 568 578 581 575 575 565 607 647 654 664 661 705 690 686 685 707 717 719 711 712 7413-year 451 471 491 523 525 529 546 534 540 523 566 614 619 628 625 675 658 649 664 669 684 687 681 6804-year 402 425 449 486 494 498 515 500 512 496 550 596 588 608 598 647 634 627 634 661 668 673 6585-year 361 384 414 458 480 475 489 479 490 468 531 584 571 588 584 628 617 604 607 644 644 6586-year 329 360 391 436 463 457 457 461 463 458 517 569 557 567 574 613 604 591 590 633 6397-year 310 335 368 411 447 442 439 450 451 440 505 563 540 557 561 595 600 579 581 6158-year 291 316 344 391 416 428 434 434 438 431 491 557 527 542 550 585 585 567 5639-year 273 299 326 375 409 416 414 425 429 431 479 537 517 534 538 577 579 56310-year 260 282 315 363 399 405 398 410 414 418 470 525 503 520 526 568 57011-year 248 269 295 347 378 397 384 404 404 404 457 518 487 503 523 56012-year 235 251 285 338 372 382 374 399 394 398 447 507 470 494 51613-year 228 239 275 329 365 374 367 393 385 386 443 483 465 48014-year 221 232 267 323 355 360 364 387 381 370 434 472 45315-year 215 225 264 318 353 348 361 371 369 367 427 46616-year 207 217 258 310 353 344 360 363 364 362 42017-year 202 210 251 304 342 340 358 361 351 35518-year 198 205 248 301 336 334 348 361 34819-year 193 199 241 296 330 326 348 36120-year 191 196 238 291 322 323 335

Table 1319Leukemia

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 20: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 009 012 155 080 Asian 0 005 008 011 101 060

10 003 006 010 151 080 Pacific 10 003 006 009 096 060

20 003 007 014 148 080 Islander 20 003 006 011 094 060

30 004 011 026 146 080 30 003 008 016 091 059

40 007 022 050 144 080 40 005 013 027 088 059

50 015 044 089 140 080 50 008 022 047 085 058

60 031 078 120 133 081 60 015 040 066 079 057

70 053 100 - 114 079 70 027 054 - 068 053

80 062 - - 081 068 80 032 - - 049 042

White 0 006 010 013 163 084 American 0 005 007 009 079 042

10 004 007 011 159 084 Indian 10 002 004 007 075 041

20 003 007 014 156 084 Alaska 20 002 005 009 073 041

30 004 011 027 154 083 Nativea 30 003 007 017 073 041

40 008 023 053 152 084 40 004 014 028 071 042

50 016 047 095 148 084 50 010 025 051 070 042

60 033 083 127 140 085 60 016 044 058 064 043

70 057 106 - 120 083 70 032 048 - 055 041

80 066 - - 084 071 80 021 - - 030 032

Black 0 003 006 008 105 057 Hispanicb 0 007 011 015 124 065

10 002 005 008 104 058 10 005 008 012 118 065

20 002 006 012 102 058 20 004 008 014 114 065

30 004 010 022 101 058 30 004 010 021 111 064

40 007 018 040 099 058 40 006 017 036 108 063

50 012 035 064 096 058 50 010 030 063 103 062

60 024 056 081 091 058 60 021 054 085 097 061

70 038 068 - 079 056 70 037 070 - 084 058

80 042 - - 058 048 80 041 - - 058 049

Table 1320

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 21: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 010 013 183 094 Asian 0 005 009 012 121 075

10 004 007 012 179 095 Pacific 10 003 007 010 116 076

20 003 008 016 176 095 Islander 20 003 007 012 113 075

30 005 013 030 175 095 30 004 009 018 110 075

40 008 026 062 174 096 40 005 014 033 107 074

50 018 055 111 170 097 50 009 027 061 103 074

60 039 099 150 163 099 60 019 054 085 098 073

70 070 128 - 144 099 70 038 071 - 086 069

80 082 - - 104 087 80 041 - - 058 055

White 0 007 011 014 193 099 American 0 005 007 009 104 052

10 004 008 012 189 099 Indian 10 002 005 008 101 052

20 004 008 016 185 099 Alaska 20 002 006 010 099 052

30 005 013 031 184 099 Nativea 30 004 008 020 099 052

40 009 027 065 183 100 40 004 016 037 099 053

50 019 058 117 180 101 50 013 035 073 099 055

60 042 105 159 172 104 60 024 066 082 095 058

70 074 136 - 151 103 70 049 067 - 082 056

80 087 - - 109 090 80 026 - - 047 044

Black 0 003 006 008 118 062 Hispanicb 0 007 013 017 140 077

10 003 005 009 117 063 10 005 010 015 134 077

20 002 006 014 115 063 20 005 009 016 129 076

30 004 012 025 115 064 30 005 012 023 126 075

40 008 022 047 114 064 40 007 018 040 123 075

50 015 041 075 111 065 50 012 034 072 119 074

60 029 067 097 107 066 60 023 064 100 114 074

70 048 084 - 097 066 70 046 087 - 102 073

80 056 - - 075 058 80 053 - - 073 066

Table 1321

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 22: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 006 008 011 129 067 Asian 0 005 008 010 084 048

10 003 005 009 124 067 Pacific 10 002 005 008 080 047

20 003 006 012 122 067 Islander 20 002 005 009 077 047

30 003 009 021 120 067 30 003 007 014 075 046

40 006 018 040 118 066 40 004 011 022 072 046

50 012 034 069 114 066 50 007 018 035 069 045

60 023 060 094 106 066 60 011 029 050 064 044

70 040 077 - 091 063 70 018 040 - 055 041

80 047 - - 064 055 80 025 - - 042 034

White 0 006 009 011 135 070 American 0 005 007 008 056 032

10 003 005 009 130 070 Indian 10 002 003 006 051 032

20 003 006 012 128 069 Alaska 20 002 004 008 050 031

30 003 010 022 126 069 Nativea 30 003 007 014 049 031

40 006 019 042 124 069 40 004 012 019 047 032

50 013 036 073 119 069 50 008 015 031 044 031

60 025 063 099 111 068 60 008 025 038 038 031

70 042 082 - 095 066 70 019 033 - 033 030

80 050 - - 067 057 80 019 - - 019 025

Black 0 004 006 008 096 053 Hispanicb 0 006 010 013 110 057

10 002 004 007 093 054 10 004 007 010 104 057

20 002 005 011 092 054 20 003 006 012 101 056

30 003 009 018 090 053 30 004 009 018 098 055

40 006 016 034 088 053 40 006 015 033 095 055

50 010 029 055 085 052 50 009 027 054 090 054

60 020 048 070 080 052 60 019 046 072 084 052

70 031 056 - 067 050 70 030 057 - 070 048

80 034 - - 048 042 80 033 - - 048 039

Table 1322

Leukemia

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 23: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 141 181 110 -05 -06 -05 -03 02 03

White 150 192 116 -06 -07 -06 -03 03 05White Hispanice 113 136 94 01 -02 02 - - -White Non-Hispanice 154 198 118 -05 -07 -05 - - -

Black 108 136 89 01 01 04 01 01 02

AsianPacific Islander 80 99 65 02 02 03 - - -

Amer IndAlaska Natf 81 107 60 04 17 -06 - - -

Hispanice 109 132 91 02 00 03 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 64 86 48 -16 -17 -13

White 67 89 50 -15 -16 -12White Hispanice 49 62 40 -07 -09 -06White Non-Hispanice 68 91 50 -15 -16 -13

Black 54 70 43 -16 -18 -15

AsianPacific Islander 36 48 26 -06 -04 -26

Amer IndAlaska NatTotal US 31 39 23 -22 -13 -31PRCDA Counties 40 51 30 -17 -08 -27Non-PRCDA Counties 20 26 16 -27 -18 -37

Hispanice 46 58 38 -09 -10 -07

Table 1323Leukemia

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 24: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1236 1572 956 1338 1701 1030 1010 1298 794Greater Bay Area 1203 1585 887 1371 1803 1002 1084 1401 838San Francisco-Oakland 1179 1566 865 1342 1781 973 1081 1387 843San Jose-Monterey 1243 1615 922 1408 1831 1038 1136 1478 -

Los Angeles 1162 1444 934 1282 1607 1014 1011 1251 848Greater California 1280 1623 991 1348 1704 1043 981 1297 722

Connecticut 1418 1746 1156 1441 1758 1184 987 1189 850Detroit 1582 2071 1209 1708 2238 1288 1175 1470 976Georgia 1444 1849 1133 1558 1983 1211 1161 1512 945Atlanta 1417 1871 1084 1604 2077 1226 1182 1629 908Rural Georgia 1543 1781 1314 1762 2094 1416 1173 - 1190Greater Georgia 1458 1848 1155 1543 1956 1204 1148 1450 965

Hawaii 1082 1361 842 1334 1497 1153 - - -Idaho 1618 2000 1271 1629 2020 1273 - - -Iowa 1623 2140 1203 1633 2152 1209 1366 1834 968Kentucky 1564 1970 1235 1566 1978 1230 1207 1419 1037Louisiana 1399 1782 1099 1513 1907 1196 1108 1404 881Massachusetts 1169 1488 920 1177 1510 915 867 1052 746New Jersey 1548 1982 1217 1585 2022 1249 1081 1360 906New Mexico 1327 1600 1092 1346 1625 1106 1049 - -New York 1625 2116 1247 1760 2294 1336 1062 1316 901Seattle-Puget Sound 1564 2035 1168 1640 2115 1235 1350 1688 1033Utah 1390 1807 1025 1399 1826 1024 - - -

SEER 9 Areasb 1421 1832 1088 1522 1952 1165 1158 1478 936SEER 13 Areasb 1355 1737 1045 1472 1882 1131 1119 1417 912SEER 18 Areasb 1380 1759 1073 1469 1868 1138 1105 1397 901SEER 21 Areasb 1414 1809 1097 1502 1920 1160 1083 1363 893

Table 1324Leukemia

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 25: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 603 794 457 657 866 496 535 686 433Greater Bay Area 551 744 406 626 848 457 519 706 397San Francisco-Oakland 541 749 387 620 858 439 502 691 374San Jose-Monterey 567 733 441 634 831 485 632 - -

Los Angeles 597 780 460 666 874 508 535 674 447Greater California 624 816 474 662 865 501 536 682 428

Connecticut 601 790 466 619 811 480 522 682 410Detroit 652 894 481 689 955 496 547 694 451Georgia 612 800 474 640 840 484 540 687 450Atlanta 568 740 448 619 805 484 476 603 389Rural Georgia 631 701 567 679 810 - - - -Greater Georgia 635 831 487 649 854 485 586 756 488

Hawaii 467 610 358 594 692 494 - - -Idaho 672 866 508 680 881 509 - - -Iowa 687 967 482 692 968 491 - - -Kentucky 723 909 582 734 917 595 571 782 415Louisiana 652 862 501 680 912 507 576 706 491Massachusetts 609 823 456 636 861 473 422 515 371New Jersey 618 816 478 657 868 505 492 588 428New Mexico 526 697 388 554 735 407 - - -New York 611 817 466 660 880 501 465 606 377Seattle-Puget Sound 622 811 475 638 816 499 738 1072 491Utah 673 854 526 685 864 540 - - -

SEER 9 Areasb 601 804 450 641 853 482 523 690 412SEER 13 Areasb 598 794 453 648 857 490 525 682 421SEER 18 Areasb 619 815 473 660 868 502 540 686 443SEER 21 Areasb 618 817 471 659 870 500 514 658 421

Total US 642 857 480 669 893 498 538 699 433

Table 1325Leukemia

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 26: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 642 002

High Five StatesOklahoma 754 019 01(0111) 1750c

West Virginia 746 025 02(0121) 1619c

Kansas 727 021 03(0123) 1329Kentucky 723 017 04(0120) 1260Arkansas 713 020 05(0126) 1113

Low Five StatesColorado 588 015 47(3049) -837Alaska 555 047 48(0751) -1355New Mexico 526 021 49(4551) -1809c

DC 488 040 50(3651) -2397c

Hawaii 467 024 51(4851) -2720c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 645 015 27(1144) 044 Montana 610 031 42(0749) -489Alaska 555 047 48(0751) -1355 Nebraska 687 025 13(0138) 700Arizona 611 013 40(2548) -478 Nevada 638 021 29(0947) -063Arkansas 713 020 05(0126) 1113 New Hampshire 617 028 38(0849) -386California 603 006 44(3448) -606 New Jersey 618 011 36(2547) -369Colorado 588 015 47(3049) -837 New Mexico 526 021 49(4551) -1809c

Connecticut 601 017 45(2448) -629 New York 611 007 41(3047) -481Delaware 652 034 26(0248) 153 North Carolina 618 011 37(2447) -373DC 488 040 50(3651) -2397c North Dakota 699 041 09(0147) 890Florida 629 007 33(2442) -206 Ohio 689 010 12(0525) 741Georgia 612 011 39(2648) -458 Oklahoma 754 019 01(0111) 1750c

Hawaii 467 024 51(4851) -2720c Oregon 636 017 31(1247) -095Idaho 672 028 20(0145) 478 Pennsylvania 664 009 23(1131) 344Illinois 662 010 24(1133) 315 Rhode Island 667 033 22(0147) 386Indiana 697 014 10(0225) 856 South Carolina 669 016 21(0536) 429Iowa 687 019 14(0234) 698 South Dakota 707 038 07(0145) 1016Kansas 727 021 03(0123) 1329 Tennessee 679 014 17(0430) 574Kentucky 723 017 04(0120) 1260 Texas 628 007 34(2443) -212Louisiana 652 016 25(0843) 158 Utah 673 024 19(0244) 481Maine 636 027 30(0548) -089 Vermont 635 041 32(0149) -100Maryland 625 014 35(2047) -260 Virginia 594 012 46(3148) -751Massachusetts 609 012 43(2648) -503 Washington 642 013 28(1444) 004Michigan 678 011 18(0628) 569 West Virginia 746 025 02(0121) 1619c

Minnesota 680 015 16(0431) 593 Wisconsin 709 015 06(0123) 1050Mississippi 690 021 11(0233) 752 Wyoming 683 046 15(0148) 645Missouri 699 014 08(0224) 899

Table 1326Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 27: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 857 003

High Five StatesKansas 1001 038 01(0122) 1675c

Oklahoma 988 033 02(0122) 1525c

Arkansas 981 036 03(0125) 1443Iowa 967 034 04(0127) 1281West Virginia 960 043 05(0135) 1203

Low Five StatesMontana 770 052 47(1051) -1017New Mexico 697 037 48(3751) -1863c

DC 678 075 49(1651) -2092c

Alaska 627 074 50(2551) -2678c

Hawaii 610 040 51(4751) -2886c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 851 027 30(1146) -069 Montana 770 052 47(1051) -1017Alaska 627 074 50(2551) -2678c Nebraska 907 044 20(0145) 585Arizona 788 021 45(2949) -801 Nevada 831 035 36(0948) -304Arkansas 981 036 03(0125) 1443 New Hampshire 835 049 35(0449) -260California 794 010 43(3447) -734 New Jersey 816 020 41(2347) -477Colorado 819 027 39(1848) -443 New Mexico 697 037 48(3751) -1863c

Connecticut 790 029 44(2249) -777 New York 817 013 40(2746) -471Delaware 925 061 14(0147) 799 North Carolina 836 019 33(1945) -244DC 678 075 49(1651) -2092c North Dakota 949 072 07(0147) 1068Florida 836 012 34(2342) -247 Ohio 919 018 15(0427) 728Georgia 800 020 42(2648) -668 Oklahoma 988 033 02(0122) 1525c

Hawaii 610 040 51(4751) -2886c Oregon 854 029 28(0846) -038Idaho 866 047 24(0248) 099 Pennsylvania 898 016 23(0730) 480Illinois 903 018 21(0631) 539 Rhode Island 935 059 11(0147) 905Indiana 932 025 12(0228) 873 South Carolina 912 028 18(0336) 641Iowa 967 034 04(0127) 1281 South Dakota 952 066 06(0146) 1113Kansas 1001 038 01(0122) 1675c Tennessee 931 025 13(0229) 866Kentucky 909 030 19(0238) 604 Texas 855 013 26(2039) -018Louisiana 862 029 25(0845) 063 Utah 854 040 29(0448) -040Maine 841 046 32(0449) -191 Vermont 900 074 22(0149) 498Maryland 855 025 27(1045) -026 Virginia 771 020 46(3349) -999Massachusetts 823 022 37(2147) -392 Washington 844 023 31(1546) -148Michigan 937 019 09(0225) 936 West Virginia 960 043 05(0135) 1203Minnesota 914 026 16(0333) 668 Wisconsin 914 025 17(0333) 667Mississippi 936 037 10(0136) 923 Wyoming 820 076 38(0151) -436Missouri 944 025 08(0126) 1014

Table 1327Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 28: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 480 002

High Five StatesWest Virginia 582 030 01(0121) 2112c

Kentucky 582 021 02(0111) 2111c

Oklahoma 580 022 03(0113) 2068c

Wyoming 566 057 04(0148) 1784c

Wisconsin 550 017 05(0119) 1461

Low Five StatesVermont 432 044 47(0351) -994Colorado 417 017 48(3151) -1318New Mexico 388 025 49(3451) -1931c

DC 358 044 50(1651) -2541c

Hawaii 358 029 51(4351) -2548c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 496 018 20(0545) 331 Montana 470 038 32(0250) -204Alaska 484 060 24(0151) 087 Nebraska 514 030 12(0146) 696Arizona 464 015 37(1448) -339 Nevada 466 025 34(0649) -292Arkansas 513 023 13(0244) 684 New Hampshire 440 032 46(0751) -829California 457 006 43(2647) -487 New Jersey 478 013 28(1246) -055Colorado 417 017 48(3151) -1318 New Mexico 388 025 49(3451) -1931c

Connecticut 466 019 33(1048) -291 New York 466 009 35(2046) -292Delaware 446 038 45(0451) -722 North Carolina 460 012 40(1947) -418DC 358 044 50(1651) -2541c North Dakota 495 047 22(0151) 307Florida 459 008 41(2447) -441 Ohio 521 012 09(0426) 843Georgia 474 013 30(1146) -127 Oklahoma 580 022 03(0113) 2068c

Hawaii 358 029 51(4351) -2548c Oregon 465 019 36(0848) -310Idaho 508 033 15(0148) 579 Pennsylvania 496 011 21(0836) 329Illinois 491 011 23(0939) 214 Rhode Island 475 037 29(0250) -118Indiana 521 016 10(0331) 840 South Carolina 499 018 18(0543) 392Iowa 482 022 27(0547) 033 South Dakota 516 044 11(0149) 753Kansas 525 024 07(0141) 932 Tennessee 498 016 19(0542) 362Kentucky 582 021 02(0111) 2111c Texas 457 008 42(2647) -486Louisiana 501 019 16(0443) 440 Utah 526 029 06(0144) 961Maine 474 031 31(0350) -134 Vermont 432 044 47(0351) -994Maryland 461 016 39(1448) -410 Virginia 463 014 38(1548) -351Massachusetts 456 014 44(1848) -510 Washington 483 015 26(0846) 064Michigan 484 012 25(0943) 082 West Virginia 582 030 01(0121) 2112c

Minnesota 500 017 17(0443) 412 Wisconsin 550 017 05(0119) 1461Mississippi 508 024 14(0244) 582 Wyoming 566 057 04(0148) 1784c

Missouri 522 016 08(0331) 865

Table 1328Leukemia

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 29: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 157262 105314 67081 40842 27001 397501 37481 434982

Males 92815 61226 37439 22765 15190 229436 17933 247369Females 64447 44089 29642 18077 11811 168065 19548 187613

White Both Sexes 135982 92133 59212 36221 24014 347562 31583 379145Males 80710 53989 33327 20247 13614 201888 14337 216225Females 55272 38144 25884 15974 10400 145674 17246 162920

Black Both Sexes 13034 7363 4513 2574 1603 29086 4141 33227Males 7121 4011 2347 1288 857 15624 1797 17421Females 5913 3352 2166 1285 746 13462 2344 15806

Asian Both Sexes 4198 2633 1916 1184 878 10809 + +Pacific Males 2395 1512 985 667 462 6022 + +Islander Females 1803 1121 931 516 416 4787 + +

Hispanic Both Sexes 15475 10295 7211 4736 3447 41164 + +Males 8703 5760 4028 2528 2013 23031 + +Females 6772 4536 3182 2209 1434 18133 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 01226 00328 00666 00660 00413 00586 01107 02311 04153 05334 01095

Males 01438 00337 00738 00719 00459 00680 01352 02956 05483 07262 01355Females 01022 00319 00591 00599 00367 00493 00872 01728 03041 04134 00878

White Both Sexes 01373 00364 00744 00753 00450 00611 01164 02458 04398 05658 01175Males 01610 00372 00825 00812 00503 00706 01421 03122 05787 07671 01445Females 01141 00355 00659 00691 00395 00514 00914 01843 03211 04382 00944

Black Both Sexes 00639 00154 00346 00318 00305 00484 00803 01489 02568 03116 00687Males 00715 00146 00386 00356 00304 00543 00982 01866 03373 04390 00846Females 00568 00162 00305 00279 00306 00432 00647 01188 02005 02479 00574

Asian Both Sexes 00518 00285 00517 00448 00248 00398 00587 00903 01325 01418 00531Pacific Males 00602 00298 00552 00513 00279 00471 00693 01190 01671 01979 00635Islander Females 00441 00272 00481 00382 00220 00333 00495 00672 01049 01052 00446

Hispanic Both Sexes 00708 00370 00781 00779 00440 00522 00764 01257 02075 02243 00791Males 00784 00385 00877 00870 00511 00619 00872 01425 02363 02720 00904Females 00630 00355 00680 00679 00363 00422 00657 01108 01853 01948 00687

Table 1329Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 30: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex All Races Both Sexes 20797 16805 14080 12139 10481 74301 25711 100012

Males 11608 9421 7933 6538 5931 41431 13121 54552Females 9189 7384 6147 5601 4549 32870 12590 45460

White Both Sexes 17431 14514 12132 10722 9168 63967 21903 85870Males 9864 8055 6864 5736 5223 35742 11323 47066Females 7566 6459 5268 4986 3946 28225 10579 38804

Black Both Sexes 1646 1184 984 767 658 5238 1580 6818Males 826 758 552 409 345 2890 553 3443Females 819 425 432 359 312 2348 1027 3375

Asian Both Sexes 1086 735 708 475 461 3465 + +Pacific Males 559 407 387 286 255 1893 + +Islander Females 527 328 321 189 206 1572 + +

Hispanic Both Sexes 6401 4726 3621 2733 2321 19802 + +Males 3595 2744 2093 1435 1399 11266 + +Females 2805 1981 1528 1298 922 8535 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Races Both Sexes 00229 00273 00565 00493 00161 00084 00070 00066 00057 00032 00240

Males 00260 00281 00622 00549 00188 00102 00077 00070 00056 00036 00265Females 00200 00265 00506 00435 00134 00065 00064 00062 00058 00029 00214

White Both Sexes 00253 00306 00642 00574 00186 00091 00076 00071 00060 00030 00272Males 00285 00315 00707 00629 00216 00115 00082 00076 00059 00035 00300Females 00221 00297 00573 00515 00156 00067 00069 00065 00060 00028 00244

Black Both Sexes 00115 00112 00262 00204 00082 00042 00038 00026 00032 00034 00108Males 00132 00109 00299 00245 00092 00029 00049 00020 00033 00026 00119Females 00099 00114 00224 00161 00074 00053 00028 00031 00031 00038 00097

Asian Both Sexes 00166 00228 00403 00310 00076 00070 00057 00055 00061 00034 00170Pacific Males 00189 00221 00420 00373 00098 00080 00063 00063 00046 00042 00185Islander Females 00145 00235 00385 00247 00056 00062 00052 00048 00073 00029 00155

Hispanic Both Sexes 00341 00321 00674 00618 00197 00122 00116 00109 00082 00017 00299Males 00384 00332 00756 00699 00239 00146 00128 00077 00065 - 00331Females 00297 00310 00589 00530 00151 00096 00104 00138 00095 00028 00265

Table 1330Acute Lymphocytic Leukemia

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 31: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

0

5

10

15

20

25

1975 1985 1995 2005 20170

5

10

15

20

25

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 20170

3

6

9

12

15

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesLeukemia by Race and Sex

a

Figure 131

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1996-17 = 07Observed 1975-17 = 03

US Mortality APC2013-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 01

US Mortality APC2008-17 = -25

SEER Incidence APCsDelay Adj 1975-17 = 06Observed 1975-17 = 05

US Mortality APC2000-17 = -12

SEER Incidence APCsDelay Adj 1975-17 = 03Observed 1975-17 = 02

US Mortality APC1993-17 = -13

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 32: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

0

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 20170

1

2

3

4

5

6

7

8

1975 1985 1995 2005 2017

Chronic

Acute

SEER Observed Incidence RatesLymphocytic and Myeloid Leukemia (Acute and Chronic) by Sex

a

Figure 132

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

a

Male Female Male FemaleLymphocytic Leukemia Myeloid Leukemia

Rate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
Page 33: SEER Cancer Statistics Review 1975-2017 · 2020. 7. 24. · Leukemia Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2017 With up to

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesLeukemia Both Sexes

Figure 133

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Incidence Rates (Acute Lymphocytic Leukemia)
  • Annual Incidence Rates (Chronic Lymphocytic Leukemia)
  • Annual Incidence Rates (Acute Myeloid Leukemia)
  • Annual Incidence Rates (Chronic Myeloid Leukemia)
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • Incidence Rates by Age (Lymphocytic Leukemia)
  • Incidence Rates by Age (Myeloid Leukemia)
  • 5-year Relative and Period Survival
  • 5-year Relative and Period Survival (Lymphocytic Leukemia)
  • 5-year Relative and Period Survival (Myeloid Leukemia)
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying Both Sexes
  • Risk of DevelopingDying Males
  • Risk of DevelopingDying Females
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • US Prevalence Estimates (Acute Lymphocytic Leukemia)
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence Rates by Sex (Lymphocitic Leukemia Myeloid Leukemia)
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity