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21 . Ibuprofen (Dolofen-F, anafen, ibufenz, etc.) - Tablet 200 mg ibuprofen + 325 mg paracetamol - Tablet 100, 200, 400, 600, 800 mg - Chewable tablet 50, 100 mg - Capsule 200 mg - Suspension 100 mg/2.5 mL, 100 mg/5 mL; Pain and inflammation - Adult: 1.2-1.8 g/day in divided doses. - Maintenance: 0.6-1.2 g daily. Max: 2.4 g per day. Fever - Adult: 200-400 mg every 4-6 hr. Max: 1.2 g/day. - Child: 1-6 mth: 5 mg/kg 3-4 times daily, 6-12 mth: 50 mg 3 times daily, 1- 2 yr: 50 mg 3-4 times daily, 2-7 yr: 100 mg 3-4 times - Pain and inflammation - Pain and inflammation associated with musculoskeletal and joint disorder - Fever - Juvenile idiopathic arthritis - Active peptic ulcer - Hypersensiti vity to other NSAIDs and aspirin - Suspected necrotising enterocoliti s - Active bleeding

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21.Ibuprofen (Dolofen-F, anafen, ibufenz, etc.) Tablet 200 mg ibuprofen + 325 mg paracetamol Tablet 100, 200, 400, 600, 800 mg Chewable tablet 50, 100 mg Capsule 200 mg Suspension 100 mg/2.5 mL, 100 mg/5 mL;

Pain and inflammation

Adult: 1.2-1.8 g/day in divided doses. Maintenance: 0.6-1.2 g daily. Max: 2.4 g per day.

Fever

Adult: 200-400 mg every 4-6 hr. Max: 1.2 g/day.

Child: 1-6 mth: 5 mg/kg 3-4 times daily, 6-12 mth: 50 mg 3 times daily, 1-2 yr: 50 mg 3-4 times daily, 2-7 yr: 100 mg 3-4 times daily, >7 yr: 200 mg 3-4 times daily. Max: 40 mg/kg/day. Pain and inflammation

Pain and inflammation associated with musculoskeletal and joint disorder

Fever

Juvenile idiopathic arthritis Active peptic ulcer

Hypersensitivity to other NSAIDs and aspirin Suspected necrotising enterocolitis Active bleeding

22.Prednisone (Prednison Hexpharm, Eltazon, Inflason, Prednison Berlico, etc) Solution 5 mg prednisone in 5 mL

Solution concentrate 5 mg prednisone in 1 mL

Tablet 10 mg, 20 mg, 50 mg, 2.5 mg, 5 mg, 1 mg

Allergic conditions

Adult: Per tablet contains 5 mg prednisone. Initially, 30 mg on the 1st day, then taper by 5 mg/day until 21 tablets have been administered. Systemic lupus erythematosus

Adult: Mild: 10 mg/day; Refractory or severe: 20-60 mg/day.

Rheumatoid arthritis

Adult: 10 mg daily.Acute asthma

Adult: 40-60 mg daily for 3-10 days; dose given as 1-2 divided doses Allergic conditions

Systemic lupus erythematosus

Rheumatoid arthritis

Acute asthma

Pemphigus

Bullous dermatitis herpetiformis

Severe erythema multiforme (Stevens-Johnson syndrome)

Exfoliative dermatitis

Mycosis fungoides

Severe psoriasis

Severe seborrheic dermatitis Varicella Systemic fungal infection

23.Dexamethasone (Camidexon, Kalmethasone, Dexa-M) Tablet 0,5mg, 0,75mg, 1mg, 1,5mg, 2mg, 4mg, 6mg Injectable suspension 4mg/mL, 10mg/mL Elixir Oral solution : 0,5mg/5mL Oral concentrate : 1mg/1mLAnti-inflammatory

Adult: 0.75-9 mg daily in 2-4 divided doses; may also be given via IM/IV admin.

Child: 1 mth-18 yr: 10-100 mcg/kg daily in 1-2 divided doses via oral administration adjusted according to response; up to 300 micrograms/kg daily may be used in emergency situations.

Inflammatory joint diseases

Adult: 0.8-4 mg depending on the size of the affected joint. For soft-tissue inj, 2-6 mg may be used. May repeat inj every 3-5 days to every 2-3 wk.

Bacterial meningitis

Adult: 0.15 mg/kg 4 times daily, to be given 10-20 min before or with the 1st dose of anti-infective treatment.

Child: As phosphate: 2 mth-18 yr: 150 mcg/kg every 6 hr for 4 days, starting before or with 1st dose of antibacterial treatment. Anti-inflammatory

Acute exacerbations in multiple sclerosis

Cerebral oedema caused by malignancy

Intra-articular

Inflammatory joint diseases

Unresponsive shock

Bacterial meningitis

Ocular inflammation

Hypersensitivity Active untreated infections

Ophthalmic use in viral, fungal disease of the eye

24.Metilprednisolon (Meproson, Methylprednisolone Hexpharm, Advantan, etc) Tablet : 4mg, 8mg, 16mg, 32mg

Injectable suspension : 20 mg/mL, 40 mg/mL, 80 mg/mL Powder for Injection : 40mg, 125mg, 500mg, 1g, 2g.Anti-inflammatory or immunosuppressive

Adult: Initially, 2-60 mg/day in 1-4 divided doses, followed by gradual reduction in dosage to the lowest possible level Child: As sodium succinate: 0.5-1.7 mg/kg/day or 5-25 mg/m2/day in divided doses every 6-12 hrStatus asthmaticus

Adult: (as sodium succinate) Loading dose: 2 mg/kg/dose, then 0.5-1 mg/kg/dose every 6 hr for up to 5 days. Children: (as sodium succinate) Loading dose: 2 mg/kg/dose, then 0.5-1 mg/kg/dose every 6 hr for up to 5 days.

Lupus nephritis

Adult: As sodium succinate: High-dose "pulse" therapy: 1 g/day for 3 days. Children: As sodium succinate: 30 mg/kg over 30 min every other day for 6 doses.

Aplastic anaemia

Adult: As sodium succinate: 1 mg/kg/day or 40 mg/day, for 4 days. After 4 days, change to oral and continue until day 10 or until symptoms of serum sickness resolve, then rapidly reduce over approx 2 wk.

Life-threatening shock

Adult: As sodium succinate: 30 mg/kg initially and repeated every 4-6 hr if needed or 100-250 mg initially and repeated at 2- 6-hr intervals as required by direct IV inj over a period of 3-15 min. Anti-inflammatory or immunosuppressive

Status asthmaticus

Lupus nephritis

Aplastic anaemia

Life-threatening shock

Serious infection except septic shock or tuberculosis meningitis Viral, fungal, and tuberculosis skin lesion

25.CTM (CTM, CTM Berlico, etc) Tablet : 4mg, 8mg, 12mg Syrup : 2mg/5mLAllergic conditions

Adult: 4 mg every 4-6 hr. Max: 24 mg daily. Child: 1-2 yr: 1 mg, 2-5 yr: 1 mg every 4-6 hr, 6-12 yr: 2 mg every 4-6 hr. Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr). Allergic conditions

Hypersensitivity, neonates.