SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-82 25 1982-91 09 1991-07 -07 2007-15 -22 -20 -22White 1975-82 26 1982-91 11 1991-07 -06 2007-15 -21 -19 -21Black 1975-84 35 1984-03 -06 2003-15 -23 -23 -23

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-07 -10 2007-15 -23 -22 -23White 1992-07 -09 2007-15 -23 -21 -23Black 1992-08 -13 2008-15 -32 -28 -32

SEER 9 Observed Incidencea 1975-2015All Races 1975-82 25 1982-91 09 1991-07 -07 2007-15 -23 -21 -23White 1975-82 26 1982-91 11 1991-07 -06 2007-15 -23 -21 -23Black 1975-85 32 1985-08 -09 2008-15 -35 -30 -35

SEER 13 Observed Incidenceb 1992-2015All Races 1992-07 -10 2007-15 -25 -23 -25White 1992-07 -09 2007-15 -25 -23 -25White NHef 1992-07 -07 2007-15 -23 -22 -23

Black 1992-08 -13 2008-15 -35 -30 -35Black NHef 1992-08 -12 2008-15 -34 -29 -34

APIe 1992-05 -04 2005-15 -15 -15 -15AIANeg 1992-15 -12 -12 -12Hispanicf 1992-15 -13 -13 -13

US Cancer Mortalityc 1975-2015All Races 1975-80 30 1980-90 18 1990-95 -02 1995-05 -10 2005-12 -23 2012-15 -34 -27 -31White 1975-80 29 1980-90 18 1990-95 -01 1995-05 -08 2005-10 -21 2010-15 -29 -25 -29Black 1975-81 35 1981-90 19 1990-95 -07 1995-04 -17 2004-13 -27 2013-15 -50 -32 -38

US Cancer Mortalityc 1992-2015All Races 1992-04 -08 2004-10 -21 2010-15 -30 -26 -30White 1992-03 -07 2003-09 -17 2009-15 -28 -24 -28White NHef 1992-03 -05 2003-09 -15 2009-15 -27 -23 -27

Black 1992-97 -11 1997-04 -18 2004-13 -26 2013-15 -50 -32 -38Black NHef 1992-95 -06 1995-04 -17 2004-13 -26 2013-15 -50 -31 -38

APIe 1992-08 -11 2008-15 -18 -16 -18AIANeg 1992-08 02 2008-15 -24 -18 -24Hispanicf 1992-95 14 1995-04 -12 2004-15 -24 -24 -24

Table 151Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Both Sexes by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-82 15 1982-91 -05 1991-08 -17 2008-15 -29 -26 -29White 1975-81 15 1981-90 -02 1990-08 -17 2008-15 -28 -26 -28Black 1975-84 29 1984-98 -14 1998-15 -29 -29 -29

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-08 -19 2008-15 -30 -27 -30White 1992-08 -19 2008-15 -29 -27 -29Black 1992-15 -27 -27 -27

SEER 9 Observed Incidencea 1975-2015All Races 1975-82 15 1982-91 -05 1991-08 -17 2008-15 -31 -28 -31White 1975-81 15 1981-90 -02 1990-09 -17 2009-15 -33 -28 -33Black 1975-84 29 1984-98 -13 1998-15 -30 -30 -30

SEER 13 Observed Incidenceb 1992-2015All Races 1992-08 -19 2008-15 -32 -29 -32White 1992-09 -19 2009-15 -34 -29 -34White NHef 1992-09 -18 2009-15 -32 -27 -32

Black 1992-09 -24 2009-15 -48 -40 -48Black NHef 1992-09 -24 2009-15 -46 -39 -46

APIe 1992-05 -08 2005-15 -22 -22 -22AIANeg 1992-15 -18 -18 -18Hispanicf 1992-15 -21 -21 -21

US Cancer Mortalityc 1975-2015All Races 1975-78 24 1978-84 12 1984-91 03 1991-05 -19 2005-12 -30 2012-15 -40 -33 -37White 1975-80 19 1980-87 07 1987-91 01 1991-05 -17 2005-12 -29 2012-15 -39 -32 -36Black 1975-82 29 1982-90 13 1990-94 -13 1994-03 -27 2003-13 -34 2013-15 -54 -39 -44

US Cancer Mortalityc 1992-2015All Races 1992-05 -19 2005-12 -30 2012-15 -40 -33 -37White 1992-05 -18 2005-11 -28 2011-15 -37 -32 -37White NHef 1992-05 -16 2005-12 -28 2012-15 -38 -31 -36

Black 1992-94 -10 1994-03 -27 2003-13 -34 2013-15 -54 -38 -44Black NHef 1992-94 -06 1994-04 -27 2004-13 -33 2013-15 -54 -38 -44

APIe 1992-08 -14 2008-15 -27 -24 -27AIANeg 1992-15 -12 -12 -12Hispanicf 1992-94 32 1994-05 -20 2005-15 -34 -34 -34

Table 152Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-82 56 1982-91 34 1991-06 05 2006-15 -15 -15 -15White 1975-88 48 1988-97 14 1997-07 02 2007-15 -15 -13 -15Black 1975-90 42 1990-06 06 2006-15 -18 -18 -18

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-06 01 2006-15 -17 -17 -17White 1992-97 08 1997-07 -02 2007-15 -17 -16 -17Black 1992-05 08 2005-15 -17 -17 -17

SEER 9 Observed Incidencea 1975-2015All Races 1975-82 56 1982-91 34 1991-07 04 2007-15 -18 -16 -18White 1975-88 48 1988-97 14 1997-07 03 2007-15 -17 -15 -17Black 1975-90 42 1990-06 06 2006-15 -19 -19 -19

SEER 13 Observed Incidenceb 1992-2015All Races 1992-07 00 2007-15 -20 -18 -20White 1992-07 00 2007-15 -20 -18 -20White NHef 1992-07 02 2007-15 -19 -17 -19

Black 1992-05 08 2005-15 -19 -19 -19Black NHef 1992-05 08 2005-15 -19 -19 -19

APIe 1992-15 01 01 01AIANeg 1992-05 24 2005-15 -36 -36 -36Hispanicf 1992-15 -04 -04 -04

US Cancer Mortalityc 1975-2015All Races 1975-82 60 1982-90 42 1990-95 17 1995-03 03 2003-09 -11 2009-15 -23 -19 -23White 1975-83 58 1983-90 41 1990-94 21 1994-03 05 2003-09 -10 2009-15 -22 -18 -22Black 1975-82 63 1982-92 37 1992-04 03 2004-13 -19 2013-15 -47 -25 -33

US Cancer Mortalityc 1992-2015All Races 1992-95 13 1995-03 04 2003-09 -11 2009-15 -23 -19 -23White 1992-95 14 1995-03 05 2003-09 -09 2009-15 -22 -18 -22White NHef 1992-95 17 1995-03 06 2003-09 -08 2009-15 -21 -17 -21

Black 1992-04 04 2004-13 -19 2013-15 -47 -25 -33Black NHef 1992-97 13 1997-05 00 2005-13 -18 2013-15 -46 -25 -32

APIe 1992-15 -05 -05 -05AIANeg 1992-05 21 2005-15 -17 -17 -17Hispanicf 1992-03 05 2003-15 -12 -12 -12

Table 153Cancer of the Lung and Bronchus (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046 8050-8052

8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-8241 8243-82468249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 8550 8560 85628570-8572 8574-8576

c Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2011-15

SEER 9 Observed Incidencec for Small Cell Cancer of the Lung and Bronchusa 1975-2015

All Races Both Sexes 1975-82 62 1982-89 13 1989-15 -24 -24All Races Male 1975-81 56 1981-88 00 1988-15 -31 -31All Races Female 1975-82 96 1982-91 31 1991-15 -19 -19

White Both Sexes 1975-82 63 1982-89 15 1989-15 -23 -23White Male 1975-78 89 1978-86 20 1986-15 -30 -30White Female 1975-82 102 1982-91 32 1991-15 -17 -17

Black Both Sexes 1975-86 49 1986-15 -25 -25Black Male 1975-85 50 1985-15 -34 -34Black Female 1975-91 46 1991-15 -19 -19

SEER 9 Observed Incidencec for Non-Small Cell Cancer of the Lung and Bronchusb 1975-2015

All Races Both Sexes 1975-80 52 1980-88 17 1988-00 -09 2000-03 62 2003-15 -17 -17All Races Male 1975-84 29 1984-00 -17 2000-03 47 2003-15 -25 -25All Races Female 1975-88 52 1988-99 05 1999-05 39 2005-15 -13 -13

White Both Sexes 1975-79 61 1979-88 19 1988-00 -08 2000-03 61 2003-15 -17 -17White Male 1975-80 44 1980-88 05 1988-99 -23 1999-02 53 2002-15 -23 -23White Female 1975-78 104 1978-88 49 1988-00 07 2000-03 71 2003-15 -09 -09

Black Both Sexes 1975-84 45 1984-00 -12 2000-03 56 2003-15 -23 -23Black Male 1975-84 39 1984-00 -22 2000-03 43 2003-15 -33 -33Black Female 1975-90 50 1990-97 -15 1997-05 40 2005-15 -18 -18

Table 154Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

Trends in SEER 9 Observed Incidencec Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints

By Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 5622 9432 2833 5560 9359 2839 7201 12585 30721980 6065 9996 3222 5942 9769 3237 8662 15143 38251981 6203 9941 3511 6153 9844 3552 8231 14296 37451982 6329 10069 3673 6305 9968 3768 8037 14106 35681983 6345 9946 3788 6303 9763 3909 8662 15134 39491984 6549 10205 3945 6433 9989 3961 9293 15884 44821985 6461 9859 4025 6397 9684 4087 8956 14968 46041986 6577 9903 4229 6514 9732 4294 9294 15627 48671987 6790 10151 4416 6808 10066 4549 8476 14359 43281988 6805 9870 4633 6826 9792 4773 8824 14493 48261989 6756 9796 4612 6757 9706 4726 8904 14277 51371990 6808 9691 4779 6823 9611 4896 8678 13717 52131991 6919 9720 4958 6896 9588 5063 9313 14476 57031992 6946 9721 4985 6892 9490 5104 9399 14873 56061993 6775 9395 4915 6780 9251 5063 8636 13535 52541994 6717 9093 5054 6728 9013 5161 8716 13139 56531995 6685 8982 5043 6709 8795 5243 8587 13894 50121996 6646 8797 5124 6678 8666 5297 8457 12835 55731997 6662 8631 5259 6720 8480 5493 8227 12954 50491998 6755 8802 5299 6800 8656 5504 8752 13101 58201999 6584 8458 5250 6629 8326 5442 8456 12246 58852000 6414 8211 5123 6466 8077 5322 8071 11509 57812001 6415 8140 5164 6502 8105 5347 8067 11460 57822002 6406 8043 5250 6479 7984 5423 8144 11310 60642003 6475 8102 5309 6549 7953 5565 8120 11956 55732004 6224 7628 5207 6279 7531 5377 7616 10527 57022005 6303 7582 5384 6401 7554 5579 7469 9797 59492006 6229 7430 5343 6283 7309 5536 7662 10098 59822007 6211 7377 5360 6314 7289 5606 7422 10080 56622008 6044 7222 5190 6119 7080 5434 7513 10362 56142009 6008 7078 5234 6076 6983 5420 7445 9835 58712010 5783 6812 5019 5893 6792 5221 6725 8592 54972011 5639 6582 4948 5741 6547 5151 6610 8677 52702012 5544 6426 4889 5586 6313 5048 6990 8983 56452013 5435 6202 4866 5506 6109 5061 6380 8200 51662014 5350 6064 4824 5490 6072 5070 6044 7535 50642015 5205 5904 4680 5299 5839 4895 6035 7627 4996

Table 155Cancer of the Lung and Bronchus (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 6197 8327 4631 6233 8268 4747 7744 11547 51031975-1979 5622 9432 2833 5560 9359 2839 7201 12585 30721980 6065 9996 3222 5942 9769 3237 8662 15143 38251981 6203 9941 3511 6153 9844 3552 8231 14296 37451982 6329 10069 3673 6305 9968 3768 8037 14106 35681983 6345 9946 3788 6303 9763 3909 8662 15134 39491984 6549 10205 3945 6433 9989 3961 9293 15884 44821985 6461 9859 4025 6397 9684 4087 8956 14968 46041986 6577 9903 4229 6514 9732 4294 9294 15627 48671987 6790 10151 4416 6808 10066 4549 8476 14359 43281988 6805 9870 4633 6826 9792 4773 8824 14493 48261989 6756 9796 4612 6757 9706 4726 8904 14277 51371990 6808 9691 4779 6823 9611 4896 8678 13717 52131991 6919 9720 4958 6896 9588 5063 9313 14476 57031992 6946 9721 4985 6892 9490 5104 9399 14873 56061993 6775 9395 4915 6780 9251 5063 8636 13535 52541994 6717 9093 5054 6728 9013 5161 8716 13139 56531995 6685 8982 5043 6709 8795 5243 8587 13894 50121996 6646 8797 5124 6678 8666 5297 8457 12835 55731997 6662 8631 5259 6720 8480 5493 8227 12954 50491998 6755 8802 5299 6800 8656 5504 8752 13101 58201999 6584 8458 5250 6629 8326 5442 8456 12246 58852000 6414 8211 5123 6466 8077 5322 8071 11509 57812001 6415 8140 5164 6502 8105 5347 8067 11460 57822002 6406 8043 5250 6479 7984 5423 8144 11310 60642003 6475 8102 5309 6549 7953 5565 8120 11956 55732004 6224 7628 5207 6279 7531 5377 7616 10527 57022005 6303 7582 5384 6401 7554 5579 7469 9797 59492006 6229 7430 5343 6283 7309 5536 7662 10098 59822007 6208 7373 5357 6310 7285 5602 7413 10068 56552008 6037 7214 5183 6111 7071 5428 7496 10338 56012009 5997 7065 5225 6065 6971 5410 7419 9801 58502010 5769 6796 5007 5879 6776 5208 6694 8553 54712011 5622 6562 4933 5723 6527 5135 6573 8628 52412012 5524 6402 4871 5565 6290 5030 6940 8917 56062013 5403 6166 4837 5473 6073 5032 6321 8126 51172014 5301 6008 4780 5437 6013 5021 5962 7432 49952015 5099 5782 4586 5185 5712 4791 5885 7437 4872

Table 156Cancer of the Lung and Bronchus (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Note Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 856 1070 696 907 1114 753 808 1103 6031975-1979 777 1214 447 797 1249 461 757 1177 4351980 911 1420 525 934 1440 556 999 1753 4381981 974 1459 613 1003 1487 648 928 1587 4341982 1044 1500 717 1081 1536 762 969 1608 4921983 1039 1492 710 1078 1509 766 923 1520 4951984 1071 1524 741 1107 1571 776 1041 1499 6861985 1047 1498 710 1080 1526 752 1112 1790 6271986 1122 1557 798 1157 1605 827 1226 1770 8351987 1067 1415 822 1118 1457 886 968 1461 6201988 1138 1528 853 1191 1562 923 1049 1786 5301989 1126 1486 870 1171 1525 923 1207 1767 8351990 1067 1386 840 1128 1449 906 935 1370 6211991 1131 1399 939 1171 1432 988 1234 1592 10001992 1051 1341 845 1097 1385 896 1022 1332 8051993 1003 1234 834 1048 1264 894 943 1336 6741994 977 1169 842 1024 1197 905 995 1353 7501995 987 1230 812 1037 1264 873 950 1389 6611996 972 1209 798 1028 1248 864 880 1202 6841997 953 1086 864 1011 1112 948 786 1082 6051998 929 1086 814 986 1128 882 950 1226 7551999 882 1006 797 933 1025 878 825 1121 6052000 880 1045 759 928 1085 813 959 1180 8022001 837 986 733 891 1035 793 857 1091 6892002 829 939 754 898 986 839 721 980 5712003 822 912 760 873 938 833 793 950 6832004 812 900 749 852 925 800 864 1008 7752005 759 869 682 822 924 751 663 778 5882006 769 853 708 825 884 786 683 819 5892007 768 860 702 833 896 792 710 940 5442008 709 796 646 758 811 720 638 885 4872009 713 778 669 760 810 727 751 836 6942010 681 749 634 746 798 713 589 687 5152011 627 685 586 677 710 656 528 645 4492012 646 720 589 693 755 644 665 833 5632013 636 714 581 690 751 649 546 679 4662014 604 638 582 656 664 658 585 666 5242015 589 621 569 637 647 637 578 631 536

Table 157Small Cell Cancer of the Lung and Bronchus (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Note Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 80468050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 4245 5699 3158 4220 5596 3196 5566 8297 36401975-1979 3457 5732 1736 3374 5599 1726 4845 8622 19141980 3934 6432 2069 3813 6216 2055 5912 10314 25801981 4054 6479 2259 4000 6385 2268 5497 9467 24971982 4141 6626 2320 4081 6502 2349 5581 9781 24131983 4184 6620 2406 4116 6437 2468 6076 10714 26021984 4346 6800 2550 4207 6555 2526 6733 11665 30981985 4309 6584 2635 4224 6387 2658 6360 10717 31771986 4312 6455 2746 4234 6264 2782 6472 10968 32571987 4563 6947 2835 4527 6819 2888 6052 10401 29581988 4512 6580 3002 4501 6507 3065 5991 9694 33341989 4426 6440 2972 4387 6333 3012 6100 9784 34691990 4474 6359 3109 4442 6264 3139 5987 9231 37151991 4492 6376 3137 4414 6190 3168 6484 10215 38091992 4524 6386 3170 4440 6145 3228 6481 10487 36511993 4365 6101 3096 4348 5980 3170 5677 8994 33691994 4303 5855 3184 4269 5733 3235 5855 9039 35941995 4240 5707 3168 4219 5556 3259 5829 9315 34321996 4152 5446 3210 4144 5338 3292 5417 8130 35441997 4136 5453 3160 4149 5338 3277 5359 8462 32391998 4211 5540 3251 4235 5441 3379 5484 8306 35681999 4049 5261 3160 4052 5158 3245 5431 7949 37092000 3858 4968 3049 3876 4888 3152 4896 6938 34982001 4674 5999 3693 4706 5933 3796 6019 8671 42502002 4692 5921 3799 4689 5828 3866 6241 8595 46452003 4736 6001 3809 4759 5851 3972 6164 9240 40772004 4561 5650 3761 4566 5524 3865 5634 7961 40832005 4679 5621 3989 4690 5537 4072 5808 7500 46662006 4644 5586 3942 4620 5420 4029 6059 8176 45902007 4637 5533 3968 4648 5396 4092 5873 7968 44672008 4564 5465 3905 4563 5294 4040 5942 8134 44452009 4494 5296 3905 4520 5200 4020 5634 7521 43742010 4372 5180 3764 4420 5145 3869 5088 6434 41992011 4290 4999 3759 4312 4914 3860 5276 6999 41452012 4175 4846 3673 4157 4715 3746 5426 6933 43802013 4092 4651 3674 4100 4534 3778 4957 6389 39992014 4021 4524 3648 4081 4480 3788 4640 5813 38842015 3871 4402 3466 3884 4313 3558 4676 5942 3834

Table 158Non-Small Cell Cancer of the Lung and Bronchus (Invasive)Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 5181 7461 3518 5191 7384 3586 5889 9503 34291975-1979 4541 8014 2010 4485 7897 2021 5341 9819 19781980 4941 8471 2413 4875 8327 2422 5916 10667 24571981 4999 8516 2495 4928 8352 2510 6057 10971 25101982 5143 8679 2647 5078 8518 2672 6227 11255 26301983 5240 8704 2810 5170 8540 2828 6368 11276 28731984 5336 8822 2894 5264 8624 2927 6507 11798 27981985 5432 8854 3041 5368 8669 3081 6576 11750 29641986 5504 8895 3141 5436 8703 3176 6695 11918 31001987 5624 9005 3272 5556 8809 3304 6865 12177 32481988 5697 8987 3414 5635 8786 3457 6918 12215 33541989 5790 8977 3577 5721 8757 3627 7104 12472 34871990 5885 9056 3685 5818 8840 3731 7206 12517 36481991 5899 8988 3761 5838 8776 3812 7164 12358 37161992 5890 8801 3870 5834 8598 3921 7135 12106 38551993 5913 8760 3928 5866 8552 3997 7112 12198 37721994 5854 8569 3962 5815 8378 4030 7015 11863 38611995 5838 8437 4026 5808 8262 4097 6928 11608 38841996 5791 8282 4041 5769 8115 4122 6830 11318 39081997 5751 8133 4082 5731 7983 4152 6789 11021 40531998 5708 7989 4098 5693 7847 4169 6686 10740 40671999 5542 7697 4015 5531 7567 4086 6500 10361 40002000 5585 7648 4112 5599 7541 4208 6377 10087 39642001 5532 7532 4101 5555 7434 4205 6254 9932 38802002 5500 7367 4160 5531 7289 4264 6205 9559 40212003 5419 7203 4129 5452 7132 4230 6092 9296 40252004 5337 7043 4096 5371 6974 4199 5979 9041 39952005 5285 6949 4071 5332 6909 4170 5852 8696 40122006 5173 6739 4026 5227 6705 4136 5673 8389 39062007 5071 6517 4010 5128 6476 4130 5538 8219 38132008 4959 6373 3913 5028 6351 4040 5313 7820 36882009 4841 6154 3863 4918 6141 3997 5156 7549 35902010 4742 6005 3794 4811 5992 3917 5115 7352 36272011 4600 5787 3701 4672 5784 3820 4931 7002 35442012 4494 5621 3642 4565 5612 3764 4834 6887 34742013 4344 5395 3546 4413 5391 3664 4697 6601 34132014 4220 5195 3473 4300 5204 3599 4473 6251 32802015 4062 4976 3356 4149 4989 3492 4223 5906 3077

Table 159Cancer of the Lung and Bronchus (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 546 638 478 561 639 502 614 812 479Under 65 161 174 149 161 169 153 220 267 18165 and over 3209 3840 2751 3328 3888 2919 3336 4580 2541

All ages (WHO world std)c 383 440 337 392 440 354 445 580 349

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 01 - - - - - - - -5-9 - - - - - - - - -10-14 01 - - - - - - - -15-19 01 - 01 01 - 02 - - -20-24 03 03 03 04 03 04 - - -25-29 06 05 06 06 05 06 05 - -30-34 11 11 12 11 09 12 16 20 1235-39 27 27 26 27 27 28 26 31 2240-44 65 60 69 64 57 70 69 76 6345-49 179 174 184 178 171 185 228 226 23150-54 437 445 429 436 433 439 619 684 56155-59 820 901 743 817 876 761 1171 1423 95260-64 1330 1536 1141 1336 1491 1190 1824 2433 132765-69 2231 2548 1949 2296 2550 2064 2646 3444 202670-74 3215 3666 2834 3361 3728 3045 3435 4541 263275-79 3928 4623 3386 4098 4702 3615 4009 5478 304180-84 4094 5058 3425 4240 5132 3607 3846 5507 291185+ 3091 4284 2469 3155 4320 2545 2896 4538 2200

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 434 538 354 441 539 366 462 651 335Under 65 120 139 101 120 137 104 150 196 11265 and over 2604 3296 2100 2662 3316 2179 2618 3795 1881

All ages (WHO world std)c 297 364 244 302 363 252 326 454 236

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 00 - - - - - - - -15-19 00 00 - 00 - - - - -20-24 01 01 01 01 01 01 01 - -25-29 02 02 01 02 02 01 02 02 -30-34 05 05 04 04 04 04 08 10 0535-39 13 14 12 12 13 11 16 21 1240-44 43 42 43 44 42 45 45 49 4245-49 132 137 126 134 136 131 150 175 12850-54 333 369 299 333 360 306 430 528 34555-59 629 746 519 628 729 530 814 1068 59660-64 997 1224 789 1002 1202 815 1240 1732 84065-69 1627 1970 1320 1656 1960 1377 1838 2591 125570-74 2433 2960 1983 2493 2979 2072 2566 3632 180075-79 3092 3812 2524 3176 3849 2633 3033 4305 220780-84 3531 4557 2817 3609 4597 2907 3334 4956 244085+ 3196 4561 2498 3248 4603 2546 2900 4563 2218

Table 1510Cancer of the Lung and Bronchus (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046

8050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576

c SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Small Cell Cancer of the Lung and Bronchusa Age at DiagnosisAge-Adjusted Rates 2011-2015All ages 62 68 58 68 72 66 56 68 48Under 65 22 22 22 25 24 25 22 24 2065 and over 341 385 309 370 404 346 296 372 247

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 01 - - - - - - - -35-39 02 02 01 02 02 02 - - -40-44 06 06 06 07 06 07 05 - -45-49 22 21 23 26 24 27 19 19 1950-54 61 58 65 69 63 75 57 66 4955-59 121 123 119 133 132 134 123 129 11760-64 190 198 183 208 210 207 190 220 16565-69 306 333 282 336 352 321 268 340 21270-74 386 415 361 425 444 408 317 387 26675-79 417 462 383 451 482 426 393 489 33080-84 358 424 312 382 440 341 285 328 26185+ 173 259 128 180 264 136 162 257 122

Non-Small Cell Cancer Lung and Bronchusb Age at DiagnosisAge-Adjusted Rates 2011-2015All ages 412 482 360 419 478 373 481 635 375Under 65 128 138 118 125 132 119 182 219 15165 and over 2381 2860 2029 2448 2875 2131 2544 3505 1923

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 01 - 01 01 - - - - -20-24 03 02 03 03 03 03 - - -25-29 05 04 06 05 04 05 04 - -30-34 09 08 10 09 07 10 12 15 1035-39 23 24 23 24 24 24 23 26 2040-44 54 50 59 53 47 59 58 64 5145-49 147 142 152 142 136 149 197 196 19850-54 349 354 343 341 339 342 518 561 47955-59 644 708 583 628 676 581 974 1178 79660-64 1036 1198 888 1023 1144 908 1479 1966 108265-69 1738 1983 1520 1764 1959 1586 2160 2813 165370-74 2506 2860 2207 2595 2885 2346 2747 3610 212175-79 3017 3590 2570 3119 3619 2719 3139 4377 232280-84 2960 3700 2449 3046 3744 2551 2801 4020 211585+ 1773 2564 1361 1798 2580 1389 1644 2706 1194

Table 1511Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

SEER Incidencec Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 154 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 107 1501999-2001b 153 131 179 155 133 180 127 108 1542002-2004b 161 142 184 165 144 189 132 128 1392005-2007b 178 152 206 183 157 211 140 122 1612008-2014b 199f 167f 233f 200f 169f 232f 183f 150f 219f

5-Year Period Survival (Percent)cd

2014 190 157 227 191 158 227 164 133 203

Stage Distribution () 2008-2014ce

All StagesNumber of cases 264275 138788 125487 214482 111164 103318 30645 16916 13729Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 13 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 57 58 54 61 63 58UnstagedUnknown 5 4 5 5 5 5 4 4 4

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 332 280 381 346 290 398 273 240 311Ages 45-54 213 169 261 217 172 266 185 142 234Ages 55-64 202 168 247 203 169 245 176 145 223Ages 65-74 200 166 240 203 169 242 160 131 196Ages 75+ 141 118 162 143 120 163 113 81 140Ages lt65 212 173 259 214 175 260 183 149 231Ages 65+ 171 144 199 173 146 201 140 113 170

StageeAll Stages 186 155 220 187 157 220 162 132 198Localized 563 502 615 563 505 613 521 446 591Regional 297 262 336 296 262 333 272 237 311Distant 47 39 57 45 37 55 46 39 56UnstagedUnknown 78 72 84 70 64 76 102 83 127

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045b Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046

8050-8052 8070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-82418243-8246 8249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 85508560 8562 8570-8572 8574-8576

c SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Small Cell Cancer of the Lung and Bronchusa Age at DiagnosisAge-Adjusted Rates 2011-2015All ages 62 68 58 68 72 66 56 68 48Under 65 22 22 22 25 24 25 22 24 2065 and over 341 385 309 370 404 346 296 372 247

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 - - - - - - - - -30-34 01 - - - - - - - -35-39 02 02 01 02 02 02 - - -40-44 06 06 06 07 06 07 05 - -45-49 22 21 23 26 24 27 19 19 1950-54 61 58 65 69 63 75 57 66 4955-59 121 123 119 133 132 134 123 129 11760-64 190 198 183 208 210 207 190 220 16565-69 306 333 282 336 352 321 268 340 21270-74 386 415 361 425 444 408 317 387 26675-79 417 462 383 451 482 426 393 489 33080-84 358 424 312 382 440 341 285 328 26185+ 173 259 128 180 264 136 162 257 122

Non-Small Cell Cancer Lung and Bronchusb Age at DiagnosisAge-Adjusted Rates 2011-2015All ages 412 482 360 419 478 373 481 635 375Under 65 128 138 118 125 132 119 182 219 15165 and over 2381 2860 2029 2448 2875 2131 2544 3505 1923

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 01 - 01 01 - - - - -20-24 03 02 03 03 03 03 - - -25-29 05 04 06 05 04 05 04 - -30-34 09 08 10 09 07 10 12 15 1035-39 23 24 23 24 24 24 23 26 2040-44 54 50 59 53 47 59 58 64 5145-49 147 142 152 142 136 149 197 196 19850-54 349 354 343 341 339 342 518 561 47955-59 644 708 583 628 676 581 974 1178 79660-64 1036 1198 888 1023 1144 908 1479 1966 108265-69 1738 1983 1520 1764 1959 1586 2160 2813 165370-74 2506 2860 2207 2595 2885 2346 2747 3610 212175-79 3017 3590 2570 3119 3619 2719 3139 4377 232280-84 2960 3700 2449 3046 3744 2551 2801 4020 211585+ 1773 2564 1361 1798 2580 1389 1644 2706 1194

Table 1511Small Cell Cancer of the Lung and Bronchusa(Invasive) and Non-Small Cell Cancer of the Lung and Bronchusb(Invasive)

SEER Incidencec Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 154 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 107 1501999-2001b 153 131 179 155 133 180 127 108 1542002-2004b 161 142 184 165 144 189 132 128 1392005-2007b 178 152 206 183 157 211 140 122 1612008-2014b 199f 167f 233f 200f 169f 232f 183f 150f 219f

5-Year Period Survival (Percent)cd

2014 190 157 227 191 158 227 164 133 203

Stage Distribution () 2008-2014ce

All StagesNumber of cases 264275 138788 125487 214482 111164 103318 30645 16916 13729Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 13 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 57 58 54 61 63 58UnstagedUnknown 5 4 5 5 5 5 4 4 4

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 332 280 381 346 290 398 273 240 311Ages 45-54 213 169 261 217 172 266 185 142 234Ages 55-64 202 168 247 203 169 245 176 145 223Ages 65-74 200 166 240 203 169 242 160 131 196Ages 75+ 141 118 162 143 120 163 113 81 140Ages lt65 212 173 259 214 175 260 183 149 231Ages 65+ 171 144 199 173 146 201 140 113 170

StageeAll Stages 186 155 220 187 157 220 162 132 198Localized 563 502 615 563 505 613 521 446 591Regional 297 262 336 296 262 333 272 237 311Distant 47 39 57 45 37 55 46 39 56UnstagedUnknown 78 72 84 70 64 76 102 83 127

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 8 7 11 5 5 61970-1973a - - - 10 9 14 7 6 101975-1977b 122 111 153 123 111 154 112 105 1381978-1980b 128 113 163 129 115 162 117 97 1781981-1983b 131 115 164 133 117 166 114 102 1491984-1986b 128 112 160 130 112 163 111 103 1281987-1989b 130 119 150 133 120 153 109 108 1111990-1992b 136 121 159 140 125 162 105 93 1271993-1995b 143 125 169 145 126 171 128 112 1571996-1998b 146 129 168 148 131 170 123 107 1501999-2001b 153 131 179 155 133 180 127 108 1542002-2004b 161 142 184 165 144 189 132 128 1392005-2007b 178 152 206 183 157 211 140 122 1612008-2014b 199f 167f 233f 200f 169f 232f 183f 150f 219f

5-Year Period Survival (Percent)cd

2014 190 157 227 191 158 227 164 133 203

Stage Distribution () 2008-2014ce

All StagesNumber of cases 264275 138788 125487 214482 111164 103318 30645 16916 13729Percent 100 100 100 100 100 100 100 100 100Localized 16 14 18 17 15 19 13 12 15Regional 22 22 22 22 22 22 22 21 23Distant 57 59 55 57 58 54 61 63 58UnstagedUnknown 5 4 5 5 5 5 4 4 4

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 332 280 381 346 290 398 273 240 311Ages 45-54 213 169 261 217 172 266 185 142 234Ages 55-64 202 168 247 203 169 245 176 145 223Ages 65-74 200 166 240 203 169 242 160 131 196Ages 75+ 141 118 162 143 120 163 113 81 140Ages lt65 212 173 259 214 175 260 183 149 231Ages 65+ 171 144 199 173 146 201 140 113 170

StageeAll Stages 186 155 220 187 157 220 162 132 198Localized 563 502 615 563 505 613 521 446 591Regional 297 262 336 296 262 333 272 237 311Distant 47 39 57 45 37 55 46 39 56UnstagedUnknown 78 72 84 70 64 76 102 83 127

Table 1512Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Note Small Cell Cancer of the Lung and Bronchus includes histologies 8002 8041-8045a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesb SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

c Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundinge The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 36 31 48 37 31 49 37 38 361978-1980a 42 32 65 43 33 64 31 24 501981-1983a 45 35 62 46 36 61 53 41 821984-1986a 45 35 62 47 36 64 35 22 561987-1989a 51 39 66 51 39 68 40 33 511990-1992a 54 45 64 54 45 65 42 39 441993-1995a 64 51 79 63 50 76 67 40 1041996-1998a 58 52 65 60 54 66 36 26 451999-2001a 57 48 67 56 44 69 52 60 422002-2004a 65 47 82 65 44 84 53 53 512005-2007a 68 50 86 68 50 85 65 35 952008-2014a 67e 55e 79e 66e 53e 79e 66e 59e 70

5-Year Period Survival (Percent)bc

2014 62 47 77 62 46 76 70 53 89

Stage Distribution () 2008-2014bd

All StagesNumber of cases 34106 17114 16992 29507 14571 14936 3105 1590 1515Percent 100 100 100 100 100 100 100 100 100Localized 4 4 4 4 4 4 4 4 3Regional 19 17 21 19 17 21 20 18 22Distant 75 77 73 75 77 73 75 76 73UnstagedUnknown 2 2 2 2 2 2 2 2 1

5-Year Relative Survival (Percent) 2008-2014b

Age at DiagnosisAges lt45 134 120 151 136 122 153 93 - -Ages 45-54 86 64 108 84 58 109 109 103 117Ages 55-64 79 60 100 78 59 98 78 46 110Ages 65-74 61 48 74 61 46 76 55 54 55Ages 75+ 33 27 38 34 27 39 31 26 34Ages lt65 83 62 104 81 60 103 87 65 112Ages 65+ 49 40 59 50 39 61 46 45 47

StagedAll Stages 63 49 77 63 48 78 67 55 78Localized 285 245 322 282 236 323 345f 335f 328f

Regional 149 123 170 150 122 171 151 117 183Distant 29 22 36 29 22 35 33 27 39UnstagedUnknown 88 68 108 84 51 115 47 106f -

Table 1513Small Cell Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Note Non-Small Cell Cancer of the Lung and Bronchus includes histologies 8003-8004 8012-8015 8021-8022 8030-8035 8046 8050-80528070-8076 8078 8082-8084 8090 8094 8120 8123 8140-8141 8143-8145 8147 8190 8200-8201 8211 8240-8241 8243-82468249-8255 8260 8290 8310 8320 8323 8333 8401 843084408470-84718480-8481 8490 8503 8507 8525 8550 8560 85628570-8572 8574-8576

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tables

b SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

c Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

d Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundinge The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)f The standard error is between 5 and 10 percentage pointsg The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1975-1977a 164 148 210 167 150 214 134 124 1771978-1980a 167 148 214 170 152 215 142 116 2281981-1983a 171 150 218 175 154 221 139 122 1921984-1986a 166 144 210 170 147 215 131 119 1641987-1989a 169 152 198 173 155 205 132 129 1391990-1992a 177 155 211 183 162 217 128 111 1621993-1995a 187 161 225 193 165 232 151 133 1851996-1998a 194 167 229 199 171 235 153 128 1941999-2001a 200 168 240 207 175 246 148 120 1892002-2004a 196 170 228 204 176 237 149 139 1642005-2007a 215 183 252 225 191 263 157 136 1812008-2014a 242e 202e 286e 247e 207e 290e 210e 169e 256e

5-Year Period Survival (Percent)bc2014 233 190 281 237 194 285 188 152 233

Stage Distribution () 2008-2014bdAll StagesNumber of cases 198878 105730 93148 158856 83531 75325 24312 13524 10788Percent 100 100 100 100 100 100 100 100 100Localized 19 17 22 20 17 23 15 13 17Regional 24 24 23 24 25 24 24 23 25Distant 55 57 53 54 56 51 59 62 56UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014bAge at DiagnosisAges lt45 350 293 402 370 305 427 282 252 317Ages 45-54 240 189 295 249 197 305 196 146 251Ages 55-64 236 195 290 241 199 294 193 160 244Ages 65-74 241 200 290 248 206 295 185 150 229Ages 75+ 188 155 221 192 159 225 147 106 185Ages lt65 243 198 299 250 204 305 198 161 250Ages 65+ 217 180 256 222 185 260 170 135 210

StagedAll Stages 227 187 271 232 192 276 185 149 230Localized 601 537 656 603 542 655 552 470 628Regional 334 290 384 334 291 383 297 259 341Distant 55 45 67 53 43 65 50 41 62UnstagedUnknown 138 129 149 131 119 143 120 101 143

Table 1514Non-Small Cell Cancer of the Lung and Bronchus (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 353 372 385 395 403 399 404 399 414 409 402 407 419 422 435 440 444 452 458 449 467 459 480 4792-year 211 220 226 237 249 247 247 252 258 258 255 265 265 277 285 294 301 310 314 311 327 318 3353-year 163 169 171 183 191 193 193 198 198 202 198 207 207 223 226 235 239 248 253 249 264 2554-year 139 145 146 155 165 162 165 170 170 175 168 175 179 189 195 200 205 214 216 215 2295-year 125 129 130 138 145 146 147 146 151 157 150 155 160 168 174 176 183 188 196 1936-year 114 117 119 126 132 132 133 133 137 142 134 141 145 154 158 162 168 173 1797-year 107 108 109 116 123 121 122 122 127 129 123 129 133 142 146 151 153 1598-year 100 100 101 107 115 112 113 112 118 120 114 119 120 132 135 140 1419-year 94 92 94 99 107 103 104 105 110 112 106 111 111 125 126 12710-year 88 86 88 93 100 95 98 100 105 104 100 103 102 116 11611-year 83 81 82 86 94 88 91 94 97 97 94 95 97 10712-year 78 77 77 80 89 83 84 89 91 91 88 88 9213-year 74 72 72 75 82 79 80 81 85 86 81 8314-year 71 68 68 71 77 75 75 76 80 80 7715-year 66 64 64 67 73 70 71 71 76 7716-year 63 60 61 62 69 66 65 67 7117-year 60 56 57 59 64 63 61 6318-year 57 53 53 55 59 60 5719-year 54 50 49 52 54 5620-year 52 46 47 49 5221-year 49 43 45 4622-year 47 41 4223-year 44 38 4024-year 42 36 3825-year 40 34 3626-year 38 32 3427-year 36 3028-year 35 2929-year 33 2730-year 32 26

Table 1515Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 334 354 365 372 380 380 381 370 382 386 370 372 394 390 400 413 409 420 427 412 424 416 428 4382-year 195 202 210 216 231 230 230 226 227 237 222 231 237 247 248 268 262 278 276 273 284 280 2793-year 148 153 156 164 173 177 177 174 167 182 172 179 181 195 195 208 208 220 219 215 223 2204-year 125 129 131 137 148 145 150 147 141 155 143 150 155 166 166 173 175 189 184 185 1895-year 111 114 116 121 132 130 133 124 125 141 127 136 140 149 149 151 157 167 165 1656-year 101 104 106 110 118 117 119 110 112 126 115 122 126 136 133 140 142 152 1517-year 94 95 97 100 112 106 108 101 103 113 104 112 116 123 122 128 127 1418-year 88 87 90 91 102 98 100 91 95 107 96 101 108 114 112 119 1169-year 82 79 84 84 96 90 92 85 87 99 89 93 98 108 105 10710-year 77 74 79 79 88 82 86 80 83 91 83 86 89 100 9611-year 72 70 73 72 83 74 79 75 77 84 77 80 84 9312-year 67 66 68 67 80 69 72 70 72 77 72 74 8013-year 63 62 63 62 72 66 68 63 68 72 65 6914-year 60 58 60 58 69 63 64 60 63 66 6115-year 56 54 56 55 64 57 61 56 59 6416-year 53 50 53 51 62 54 57 53 5817-year 51 46 48 48 58 52 53 5018-year 47 44 45 45 52 49 4919-year 45 41 41 42 46 4620-year 42 38 39 40 4221-year 41 35 36 3722-year 39 33 3423-year 37 31 3224-year 34 28 3025-year 33 27 2826-year 31 25 2627-year 28 2428-year 28 2429-year 27 2230-year 26 21

Table 1516Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 404 413 422 428 435 425 433 436 454 436 442 450 449 458 474 471 482 488 491 489 513 505 534 5212-year 253 257 255 267 274 269 269 284 295 285 297 305 299 311 324 324 343 346 355 353 373 359 3953-year 202 205 197 211 216 214 212 229 236 228 230 240 238 255 261 266 273 278 289 286 307 2934-year 178 178 172 183 188 183 185 199 205 199 199 204 206 214 228 230 238 241 251 248 2705-year 161 160 154 164 164 166 164 174 183 177 177 179 183 190 202 204 212 212 229 2236-year 149 146 141 151 150 152 150 161 167 161 158 164 167 176 185 188 196 196 2097-year 140 136 129 139 139 141 140 149 156 150 146 150 153 163 172 176 181 1798-year 131 128 119 130 131 131 128 139 147 136 137 140 136 153 160 164 1699-year 124 119 112 121 123 119 119 131 138 128 127 131 126 143 148 14910-year 116 111 104 113 116 111 112 124 130 120 121 123 118 133 13911-year 111 106 98 106 110 107 106 118 121 114 113 113 112 12312-year 106 99 92 99 101 101 99 113 114 107 106 105 10613-year 102 93 88 94 94 96 93 104 107 102 101 9914-year 97 89 82 90 87 91 89 96 100 96 9515-year 92 85 78 84 84 87 83 91 95 9116-year 89 80 74 79 79 82 75 86 8817-year 84 77 70 74 73 78 72 7918-year 80 72 67 70 68 74 6719-year 77 66 63 65 65 6820-year 74 63 61 62 6321-year 69 59 59 5922-year 65 56 5523-year 62 53 5324-year 60 51 5125-year 58 48 4926-year 56 46 4827-year 54 4228-year 51 3929-year 49 3730-year 46 36

Table 1517Cancer of the Lung and Bronchus (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 624 515 Asian 0 000 000 001 545 417

10 000 001 003 631 521 Pacific 10 000 001 002 549 420

20 000 002 014 633 523 Islander 20 001 002 012 549 421

30 002 014 072 638 527 30 002 012 047 551 422

40 012 070 216 644 534 40 010 046 141 552 424

50 060 209 448 648 539 50 036 133 304 549 423

60 158 413 589 624 524 60 100 276 451 528 413

70 289 489 - 529 458 70 189 377 - 460 380

80 269 - - 323 306 80 224 - - 322 301

White 0 000 000 001 638 526 American 0 000 000 000 415 389

10 000 001 003 644 532 Indian 10 000 000 001 420 394

20 000 002 014 646 533 Alaska 20 000 001 006 422 396

30 002 014 072 651 538 Nativea 30 001 006 042 429 404

40 012 070 218 657 544 40 005 042 143 439 415

50 060 211 461 661 549 50 039 144 312 453 429

60 161 426 605 638 534 60 113 294 425 445 434

70 300 503 - 541 466 70 207 356 - 379 396

80 275 - - 326 309 80 203 - - 234 255

Black 0 000 000 001 594 476 Hispanicb 0 000 000 000 387 287

10 000 001 003 606 486 10 000 000 002 390 289

20 000 003 017 609 488 20 000 002 007 391 290

30 002 016 094 616 494 30 001 006 029 393 292

40 014 093 261 626 502 40 005 028 098 396 294

50 082 256 477 635 511 50 023 095 232 398 296

60 191 434 575 606 495 60 075 218 345 391 294

70 293 464 - 502 428 70 158 297 - 348 272

80 249 - - 304 289 80 175 - - 239 207

Table 1518

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 668 574 Asian 0 000 000 000 659 512

10 000 000 002 675 581 Pacific 10 000 000 002 664 516

20 000 002 014 678 584 Islander 20 000 002 013 666 518

30 002 014 074 686 591 30 002 012 053 669 520

40 012 074 235 695 601 40 011 052 173 672 523

50 063 230 490 705 611 50 042 165 379 672 524

60 179 460 653 691 603 60 128 351 569 655 516

70 328 554 - 598 538 70 244 483 - 577 478

80 322 - - 386 377 80 297 - - 414 388

White 0 000 000 001 667 578 American 0 000 000 000 480 418

10 000 000 002 674 585 Indian 10 000 000 001 486 425

20 000 002 014 677 587 Alaska 20 000 001 006 489 428

30 002 014 072 684 594 Nativea 30 001 006 046 500 439

40 012 072 231 694 604 40 005 047 162 516 454

50 062 226 491 703 614 50 044 166 377 538 478

60 177 462 655 690 606 60 133 365 520 541 497

70 332 558 - 599 540 70 272 455 - 480 472

80 323 - - 382 376 80 264 - - 299 309

Black 0 000 000 001 689 578 Hispanicb 0 000 000 000 436 361

10 000 001 003 704 591 10 000 000 002 440 365

20 000 003 017 709 595 20 000 002 006 442 366

30 003 017 105 722 606 30 001 006 029 446 369

40 015 105 313 738 621 40 005 028 105 450 373

50 095 313 576 758 637 50 024 103 267 456 379

60 244 539 704 742 629 60 083 258 408 457 382

70 376 588 - 636 559 70 197 366 - 421 360

80 340 - - 417 397 80 224 - - 297 280

Table 1519

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 587 462 Asian 0 000 000 001 452 342

10 000 001 003 593 467 Pacific 10 000 001 003 455 344

20 000 003 015 594 468 Islander 20 001 003 012 455 344

30 002 014 069 596 471 30 002 012 043 455 345

40 012 068 197 599 474 40 010 041 115 455 345

50 056 188 410 598 475 50 031 106 241 450 343

60 139 371 533 568 456 60 076 214 357 428 333

70 256 436 - 474 394 70 146 296 - 371 307

80 231 - - 280 258 80 174 - - 260 242

White 0 000 000 001 614 480 American 0 000 000 000 357 364

10 000 001 003 619 484 Indian 10 000 000 001 360 368

20 000 003 015 620 485 Alaska 20 000 001 006 361 370

30 002 015 071 623 487 Nativea 30 001 005 037 364 374

40 013 069 206 626 491 40 005 037 125 370 382

50 058 197 433 625 492 50 034 124 254 377 388

60 146 393 561 594 472 60 096 233 344 363 383

70 273 459 - 495 406 70 153 277 - 298 338

80 240 - - 288 262 80 160 - - 188 222

Black 0 000 000 001 515 391 Hispanicb 0 000 000 001 348 227

10 000 000 002 524 398 10 000 001 002 351 229

20 000 002 016 525 399 20 000 002 007 351 229

30 002 016 083 528 402 30 001 006 029 352 230

40 014 083 215 534 406 40 005 028 092 352 231

50 070 207 393 535 410 50 023 088 203 352 231

60 147 347 471 500 391 60 067 186 294 339 226

70 232 376 - 409 339 70 128 245 - 293 208

80 196 - - 242 230 80 141 - - 199 160

Table 1520

Cancer of the Lung and Bronchus (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 546 638 478 -23 -29 -18 -21 -28 -16

White 561 639 502 -23 -29 -18 -21 -28 -15White Hispanice 286 352 239 -13 -21 -04 - - -White Non-Hispanice 607 686 548 -22 -27 -17 - - -

Black 614 812 479 -30 -40 -19 -30 -30 -19

AsianPacific Islander 356 459 280 -15 -22 01 - - -

Amer IndAlaska Natf 373 454 312 -12 -18 -36 - - -

Hispanice 278 341 232 -13 -21 -04 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 434 538 354 -26 -33 -19

White 441 539 366 -24 -32 -18White Hispanice 199 279 140 -23 -32 -11White Non-Hispanice 465 563 390 -23 -31 -17

Black 462 651 335 -32 -38 -25

AsianPacific Islander 234 312 178 -16 -24 -05

Amer IndAlaska NatTotal US 287 353 237 -28 -22 -27CHSDA Counties 367 450 306 -18 -12 -17Non-CHSDA Counties 199 248 159 -25 -34 -25

Hispanice 189 265 133 -24 -34 -12

Table 1521Lung and Bronchus (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 4335 4921 3897 4422 4875 4086 5411 6571 4608Greater Bay Area 4226 4786 3814 4212 4465 4044 6076 7332 5171San Francisco-Oakland 4357 4873 3978 4289 4415 4223 6404 7739 5473San Jose-Monterey 3975 4622 3491 4079 4551 3729 3988 4977 3064

Los Angeles 3744 4473 3209 3661 4277 3198 5237 6361 4517Greater California 4638 5163 4242 4767 5211 4438 5278 6425 4426

Connecticut 6098 6786 5618 6204 6808 5789 5390 7140 4302Detroit 7160 8221 6419 7122 7963 6551 7763 9885 6374Georgia 6494 8287 5172 6875 8448 5682 5714 8299 4043Atlanta 5282 6369 4545 5427 6224 4891 5353 7174 4249Rural Georgia 6200 8769 4250 6330 8528 4603 5858 9648 3351Greater Georgia 7063 9114 5511 7404 9223 5997 6009 9046 3961

Hawaii 4616 5678 3762 4736 5117 4339 5144 5430 -Iowa 6360 7707 5340 6353 7688 5342 7797 9613 6429Kentucky 9348 11276 7898 9433 11367 7975 9045 10955 7693Louisiana 6883 8760 5441 6811 8237 5708 7235 10580 4897New Jersey 5734 6431 5261 5992 6603 5586 5511 6873 4678New Mexico 4027 4613 3558 4228 4788 3776 4448 5661 3581Seattle-Puget Sound 5739 6332 5293 5872 6389 5485 5932 7219 4880Utah 2759 3233 2372 2743 3207 2364 5257 6564 -

SEER 9 Areasb 5384 6173 4798 5471 6113 4999 6320 8081 5155SEER 13 Areasb 4951 5730 4373 5032 5668 4560 6008 7620 4937SEER 18 Areasb 5463 6376 4776 5613 6394 5025 6140 8122 4791

Table 1522Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 3216 3832 2750 3307 3828 2909 4164 5243 3412Greater Bay Area 2957 3508 2547 3007 3352 2752 4263 5259 3573San Francisco-Oakland 3080 3609 2688 3078 3346 2889 4528 5630 3778San Jose-Monterey 2721 3315 2271 2881 3362 2512 2561 3084 2130

Los Angeles 2859 3565 2340 2801 3412 2342 4288 5397 3566Greater California 3466 4060 3009 3580 4114 3168 3997 5096 3168

Connecticut 3747 4389 3285 3834 4406 3424 3274 4788 2329Detroit 4885 5910 4148 4855 5702 4241 5360 7264 4123Georgia 4620 6216 3447 4875 6298 3794 4093 6347 2656Atlanta 3656 4766 2891 3685 4543 3076 3825 5697 2716Rural Georgia 4746 6770 3253 4822 6425 3582 4538 7658 2551Greater Georgia 5055 6834 3718 5296 6905 4056 4298 6773 2638

Hawaii 3160 3985 2503 3438 3795 3064 4147 5363 -Iowa 4557 5805 3606 4560 5811 3606 5665 6696 4730Kentucky 6772 8667 5349 6850 8763 5405 6366 8108 5154Louisiana 5362 7061 4067 5245 6559 4226 5822 8872 3737New Jersey 3832 4593 3295 3994 4709 3490 3931 5302 3067New Mexico 3063 3628 2618 3229 3788 2786 3359 4646 2232Seattle-Puget Sound 3936 4590 3438 4063 4669 3601 4082 5013 3253Utah 1949 2389 1585 1955 2392 1594 2155 - -

SEER 9 Areasb 3701 4470 3124 3779 4446 3274 4384 6003 3319SEER 13 Areasb 3477 4229 2914 3547 4195 3055 4329 5825 3341SEER 18 Areasb 3908 4801 3231 4022 4822 3411 4514 6315 3297

Total US 4337 5383 3539 4413 5386 3664 4621 6509 3351

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4337 005

High Five StatesKentucky 6772 052 01(0101) 5615c

Arkansas 5904 058 02(0205) 3612c

West Virginia 5880 069 03(0205) 3557c

Mississippi 5742 059 04(0205) 3239c

Tennessee 5697 039 05(0305) 3136c

Low Five StatesCalifornia 3216 013 47(4748) -2585c

Hawaii 3160 062 48(4750) -2715c

New Mexico 3063 051 49(4850) -2938c

Colorado 3020 035 50(4850) -3038c

Utah 1949 042 51(5151) -5507c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5339 043 10(0610) 2309c Montana 4109 081 35(3243) -526c

Alaska 4600 138 20(1332) 607c Nebraska 4220 064 32(2737) -271Arizona 3529 030 45(4446) -1864c Nevada 4540 057 24(1727) 468Arkansas 5904 058 02(0205) 3612c New Hampshire 4558 076 22(1730) 509c

California 3216 013 47(4748) -2585c New Jersey 3832 028 42(3743) -1165c

Colorado 3020 035 50(4850) -3038c New Mexico 3063 051 49(4850) -2938c

Connecticut 3747 042 43(3744) -1361c New York 3894 019 39(3742) -1021c

Delaware 4884 094 14(1118) 1261c North Carolina 4901 030 13(1216) 1301c

DC 3889 115 40(3244) -1035c North Dakota 3952 099 37(3344) -889c

Florida 4244 018 30(2834) -215 Ohio 5171 027 11(1113) 1922c

Georgia 4620 031 19(1723) 651c Oklahoma 5570 051 06(0510) 2842c

Hawaii 3160 062 48(4750) -2715c Oregon 4233 043 31(2734) -241Idaho 3612 065 44(4346) -1671c Pennsylvania 4521 024 25(2027) 423Illinois 4635 026 18(1723) 686c Rhode Island 4827 088 17(1324) 1130c

Indiana 5345 039 09(0610) 2322c South Carolina 4884 042 15(1218) 1260c

Iowa 4557 049 23(2028) 507c South Dakota 4287 093 29(2337) -115Kansas 4591 054 21(1827) 585c Tennessee 5697 039 05(0305) 3136c

Kentucky 6772 052 01(0101) 5615c Texas 3896 018 38(3640) -1016c

Louisiana 5362 047 08(0610) 2363c Utah 1949 042 51(5151) -5507c

Maine 5156 076 12(1015) 1888c Vermont 4473 107 26(1529) 313Maryland 4154 037 34(2836) -422 Virginia 4402 032 27(2229) 149Massachusetts 4208 033 33(2834) -297 Washington 4059 033 36(3237) -641c

Michigan 4854 029 16(1418) 1191c West Virginia 5880 069 03(0205) 3557c

Minnesota 3880 036 41(3743) -1053c Wisconsin 4297 036 28(2734) -094Mississippi 5742 059 04(0205) 3239c Wyoming 3527 108 46(4146) -1867c

Missouri 5408 039 07(0610) 2468c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5383 008

High Five StatesKentucky 8667 090 01(0101) 6099c

Mississippi 8030 108 02(0203) 4916c

Arkansas 7852 101 03(0205) 4586c

West Virginia 7574 119 04(0307) 4069c

Tennessee 7510 069 05(0306) 3950c

Low Five StatesWyoming 3982 170 47(4249) -2603c

California 3832 022 48(4649) -2882c

New Mexico 3628 084 49(4750) -3261c

Colorado 3396 056 50(4950) -3691c

Utah 2389 069 51(5151) -5562c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7370 079 06(0406) 3690c Montana 4573 126 42(3746) -1505c

Alaska 5305 222 24(1740) -146 Nebraska 5250 107 27(2235) -248Arizona 4150 048 45(4347) -2291c Nevada 5114 089 31(2437) -500c

Arkansas 7852 101 03(0205) 4586c New Hampshire 5258 123 26(2237) -233California 3832 022 48(4649) -2882c New Jersey 4593 047 40(3742) -1468c

Colorado 3396 056 50(4950) -3691c New Mexico 3628 084 49(4750) -3261c

Connecticut 4389 069 43(4044) -1847c New York 4746 032 37(3641) -1185c

Delaware 5945 157 16(1222) 1043c North Carolina 6502 053 11(1013) 2077c

DC 4718 198 39(2544) -1237c North Dakota 5056 168 32(2341) -607c

Florida 5215 029 28(2431) -313 Ohio 6459 047 13(1114) 1998c

Georgia 6216 057 15(1316) 1547c Oklahoma 7004 086 08(0710) 3011c

Hawaii 3985 103 46(4449) -2599c Oregon 4827 069 36(3140) -1033c

Idaho 4194 104 44(4247) -2209c Pennsylvania 5711 040 21(1723) 609c

Illinois 5735 044 20(1723) 654c Rhode Island 5873 148 17(1526) 910c

Indiana 6841 066 09(0710) 2707c South Carolina 6492 074 12(1014) 2059c

Iowa 5805 084 19(1624) 783c South Dakota 5278 154 25(1835) -196Kansas 5591 089 22(1826) 386 Tennessee 7510 069 05(0306) 3950c

Kentucky 8667 090 01(0101) 6099c Texas 4982 031 34(2836) -746c

Louisiana 7061 083 07(0609) 3116c Utah 2389 069 51(5151) -5562c

Maine 6335 126 14(1117) 1767c Vermont 5130 172 30(1938) -470Maryland 5002 062 33(2737) -709c Virginia 5533 055 23(1926) 278Massachusetts 4949 055 35(2837) -808c Washington 4743 054 38(3440) -1189c

Michigan 5858 048 18(1619) 881c West Virginia 7574 119 04(0307) 4069c

Minnesota 4584 059 41(3843) -1485c Wisconsin 5175 059 29(2435) -388Mississippi 8030 108 02(0203) 4916c Wyoming 3982 170 47(4249) -2603c

Missouri 6733 066 10(0812) 2506c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

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0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

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Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

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a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 4335 4921 3897 4422 4875 4086 5411 6571 4608Greater Bay Area 4226 4786 3814 4212 4465 4044 6076 7332 5171San Francisco-Oakland 4357 4873 3978 4289 4415 4223 6404 7739 5473San Jose-Monterey 3975 4622 3491 4079 4551 3729 3988 4977 3064

Los Angeles 3744 4473 3209 3661 4277 3198 5237 6361 4517Greater California 4638 5163 4242 4767 5211 4438 5278 6425 4426

Connecticut 6098 6786 5618 6204 6808 5789 5390 7140 4302Detroit 7160 8221 6419 7122 7963 6551 7763 9885 6374Georgia 6494 8287 5172 6875 8448 5682 5714 8299 4043Atlanta 5282 6369 4545 5427 6224 4891 5353 7174 4249Rural Georgia 6200 8769 4250 6330 8528 4603 5858 9648 3351Greater Georgia 7063 9114 5511 7404 9223 5997 6009 9046 3961

Hawaii 4616 5678 3762 4736 5117 4339 5144 5430 -Iowa 6360 7707 5340 6353 7688 5342 7797 9613 6429Kentucky 9348 11276 7898 9433 11367 7975 9045 10955 7693Louisiana 6883 8760 5441 6811 8237 5708 7235 10580 4897New Jersey 5734 6431 5261 5992 6603 5586 5511 6873 4678New Mexico 4027 4613 3558 4228 4788 3776 4448 5661 3581Seattle-Puget Sound 5739 6332 5293 5872 6389 5485 5932 7219 4880Utah 2759 3233 2372 2743 3207 2364 5257 6564 -

SEER 9 Areasb 5384 6173 4798 5471 6113 4999 6320 8081 5155SEER 13 Areasb 4951 5730 4373 5032 5668 4560 6008 7620 4937SEER 18 Areasb 5463 6376 4776 5613 6394 5025 6140 8122 4791

Table 1522Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

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1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 3216 3832 2750 3307 3828 2909 4164 5243 3412Greater Bay Area 2957 3508 2547 3007 3352 2752 4263 5259 3573San Francisco-Oakland 3080 3609 2688 3078 3346 2889 4528 5630 3778San Jose-Monterey 2721 3315 2271 2881 3362 2512 2561 3084 2130

Los Angeles 2859 3565 2340 2801 3412 2342 4288 5397 3566Greater California 3466 4060 3009 3580 4114 3168 3997 5096 3168

Connecticut 3747 4389 3285 3834 4406 3424 3274 4788 2329Detroit 4885 5910 4148 4855 5702 4241 5360 7264 4123Georgia 4620 6216 3447 4875 6298 3794 4093 6347 2656Atlanta 3656 4766 2891 3685 4543 3076 3825 5697 2716Rural Georgia 4746 6770 3253 4822 6425 3582 4538 7658 2551Greater Georgia 5055 6834 3718 5296 6905 4056 4298 6773 2638

Hawaii 3160 3985 2503 3438 3795 3064 4147 5363 -Iowa 4557 5805 3606 4560 5811 3606 5665 6696 4730Kentucky 6772 8667 5349 6850 8763 5405 6366 8108 5154Louisiana 5362 7061 4067 5245 6559 4226 5822 8872 3737New Jersey 3832 4593 3295 3994 4709 3490 3931 5302 3067New Mexico 3063 3628 2618 3229 3788 2786 3359 4646 2232Seattle-Puget Sound 3936 4590 3438 4063 4669 3601 4082 5013 3253Utah 1949 2389 1585 1955 2392 1594 2155 - -

SEER 9 Areasb 3701 4470 3124 3779 4446 3274 4384 6003 3319SEER 13 Areasb 3477 4229 2914 3547 4195 3055 4329 5825 3341SEER 18 Areasb 3908 4801 3231 4022 4822 3411 4514 6315 3297

Total US 4337 5383 3539 4413 5386 3664 4621 6509 3351

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4337 005

High Five StatesKentucky 6772 052 01(0101) 5615c

Arkansas 5904 058 02(0205) 3612c

West Virginia 5880 069 03(0205) 3557c

Mississippi 5742 059 04(0205) 3239c

Tennessee 5697 039 05(0305) 3136c

Low Five StatesCalifornia 3216 013 47(4748) -2585c

Hawaii 3160 062 48(4750) -2715c

New Mexico 3063 051 49(4850) -2938c

Colorado 3020 035 50(4850) -3038c

Utah 1949 042 51(5151) -5507c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5339 043 10(0610) 2309c Montana 4109 081 35(3243) -526c

Alaska 4600 138 20(1332) 607c Nebraska 4220 064 32(2737) -271Arizona 3529 030 45(4446) -1864c Nevada 4540 057 24(1727) 468Arkansas 5904 058 02(0205) 3612c New Hampshire 4558 076 22(1730) 509c

California 3216 013 47(4748) -2585c New Jersey 3832 028 42(3743) -1165c

Colorado 3020 035 50(4850) -3038c New Mexico 3063 051 49(4850) -2938c

Connecticut 3747 042 43(3744) -1361c New York 3894 019 39(3742) -1021c

Delaware 4884 094 14(1118) 1261c North Carolina 4901 030 13(1216) 1301c

DC 3889 115 40(3244) -1035c North Dakota 3952 099 37(3344) -889c

Florida 4244 018 30(2834) -215 Ohio 5171 027 11(1113) 1922c

Georgia 4620 031 19(1723) 651c Oklahoma 5570 051 06(0510) 2842c

Hawaii 3160 062 48(4750) -2715c Oregon 4233 043 31(2734) -241Idaho 3612 065 44(4346) -1671c Pennsylvania 4521 024 25(2027) 423Illinois 4635 026 18(1723) 686c Rhode Island 4827 088 17(1324) 1130c

Indiana 5345 039 09(0610) 2322c South Carolina 4884 042 15(1218) 1260c

Iowa 4557 049 23(2028) 507c South Dakota 4287 093 29(2337) -115Kansas 4591 054 21(1827) 585c Tennessee 5697 039 05(0305) 3136c

Kentucky 6772 052 01(0101) 5615c Texas 3896 018 38(3640) -1016c

Louisiana 5362 047 08(0610) 2363c Utah 1949 042 51(5151) -5507c

Maine 5156 076 12(1015) 1888c Vermont 4473 107 26(1529) 313Maryland 4154 037 34(2836) -422 Virginia 4402 032 27(2229) 149Massachusetts 4208 033 33(2834) -297 Washington 4059 033 36(3237) -641c

Michigan 4854 029 16(1418) 1191c West Virginia 5880 069 03(0205) 3557c

Minnesota 3880 036 41(3743) -1053c Wisconsin 4297 036 28(2734) -094Mississippi 5742 059 04(0205) 3239c Wyoming 3527 108 46(4146) -1867c

Missouri 5408 039 07(0610) 2468c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5383 008

High Five StatesKentucky 8667 090 01(0101) 6099c

Mississippi 8030 108 02(0203) 4916c

Arkansas 7852 101 03(0205) 4586c

West Virginia 7574 119 04(0307) 4069c

Tennessee 7510 069 05(0306) 3950c

Low Five StatesWyoming 3982 170 47(4249) -2603c

California 3832 022 48(4649) -2882c

New Mexico 3628 084 49(4750) -3261c

Colorado 3396 056 50(4950) -3691c

Utah 2389 069 51(5151) -5562c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7370 079 06(0406) 3690c Montana 4573 126 42(3746) -1505c

Alaska 5305 222 24(1740) -146 Nebraska 5250 107 27(2235) -248Arizona 4150 048 45(4347) -2291c Nevada 5114 089 31(2437) -500c

Arkansas 7852 101 03(0205) 4586c New Hampshire 5258 123 26(2237) -233California 3832 022 48(4649) -2882c New Jersey 4593 047 40(3742) -1468c

Colorado 3396 056 50(4950) -3691c New Mexico 3628 084 49(4750) -3261c

Connecticut 4389 069 43(4044) -1847c New York 4746 032 37(3641) -1185c

Delaware 5945 157 16(1222) 1043c North Carolina 6502 053 11(1013) 2077c

DC 4718 198 39(2544) -1237c North Dakota 5056 168 32(2341) -607c

Florida 5215 029 28(2431) -313 Ohio 6459 047 13(1114) 1998c

Georgia 6216 057 15(1316) 1547c Oklahoma 7004 086 08(0710) 3011c

Hawaii 3985 103 46(4449) -2599c Oregon 4827 069 36(3140) -1033c

Idaho 4194 104 44(4247) -2209c Pennsylvania 5711 040 21(1723) 609c

Illinois 5735 044 20(1723) 654c Rhode Island 5873 148 17(1526) 910c

Indiana 6841 066 09(0710) 2707c South Carolina 6492 074 12(1014) 2059c

Iowa 5805 084 19(1624) 783c South Dakota 5278 154 25(1835) -196Kansas 5591 089 22(1826) 386 Tennessee 7510 069 05(0306) 3950c

Kentucky 8667 090 01(0101) 6099c Texas 4982 031 34(2836) -746c

Louisiana 7061 083 07(0609) 3116c Utah 2389 069 51(5151) -5562c

Maine 6335 126 14(1117) 1767c Vermont 5130 172 30(1938) -470Maryland 5002 062 33(2737) -709c Virginia 5533 055 23(1926) 278Massachusetts 4949 055 35(2837) -808c Washington 4743 054 38(3440) -1189c

Michigan 5858 048 18(1619) 881c West Virginia 7574 119 04(0307) 4069c

Minnesota 4584 059 41(3843) -1485c Wisconsin 5175 059 29(2435) -388Mississippi 8030 108 02(0203) 4916c Wyoming 3982 170 47(4249) -2603c

Missouri 6733 066 10(0812) 2506c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 3216 3832 2750 3307 3828 2909 4164 5243 3412Greater Bay Area 2957 3508 2547 3007 3352 2752 4263 5259 3573San Francisco-Oakland 3080 3609 2688 3078 3346 2889 4528 5630 3778San Jose-Monterey 2721 3315 2271 2881 3362 2512 2561 3084 2130

Los Angeles 2859 3565 2340 2801 3412 2342 4288 5397 3566Greater California 3466 4060 3009 3580 4114 3168 3997 5096 3168

Connecticut 3747 4389 3285 3834 4406 3424 3274 4788 2329Detroit 4885 5910 4148 4855 5702 4241 5360 7264 4123Georgia 4620 6216 3447 4875 6298 3794 4093 6347 2656Atlanta 3656 4766 2891 3685 4543 3076 3825 5697 2716Rural Georgia 4746 6770 3253 4822 6425 3582 4538 7658 2551Greater Georgia 5055 6834 3718 5296 6905 4056 4298 6773 2638

Hawaii 3160 3985 2503 3438 3795 3064 4147 5363 -Iowa 4557 5805 3606 4560 5811 3606 5665 6696 4730Kentucky 6772 8667 5349 6850 8763 5405 6366 8108 5154Louisiana 5362 7061 4067 5245 6559 4226 5822 8872 3737New Jersey 3832 4593 3295 3994 4709 3490 3931 5302 3067New Mexico 3063 3628 2618 3229 3788 2786 3359 4646 2232Seattle-Puget Sound 3936 4590 3438 4063 4669 3601 4082 5013 3253Utah 1949 2389 1585 1955 2392 1594 2155 - -

SEER 9 Areasb 3701 4470 3124 3779 4446 3274 4384 6003 3319SEER 13 Areasb 3477 4229 2914 3547 4195 3055 4329 5825 3341SEER 18 Areasb 3908 4801 3231 4022 4822 3411 4514 6315 3297

Total US 4337 5383 3539 4413 5386 3664 4621 6509 3351

Table 1523Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4337 005

High Five StatesKentucky 6772 052 01(0101) 5615c

Arkansas 5904 058 02(0205) 3612c

West Virginia 5880 069 03(0205) 3557c

Mississippi 5742 059 04(0205) 3239c

Tennessee 5697 039 05(0305) 3136c

Low Five StatesCalifornia 3216 013 47(4748) -2585c

Hawaii 3160 062 48(4750) -2715c

New Mexico 3063 051 49(4850) -2938c

Colorado 3020 035 50(4850) -3038c

Utah 1949 042 51(5151) -5507c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5339 043 10(0610) 2309c Montana 4109 081 35(3243) -526c

Alaska 4600 138 20(1332) 607c Nebraska 4220 064 32(2737) -271Arizona 3529 030 45(4446) -1864c Nevada 4540 057 24(1727) 468Arkansas 5904 058 02(0205) 3612c New Hampshire 4558 076 22(1730) 509c

California 3216 013 47(4748) -2585c New Jersey 3832 028 42(3743) -1165c

Colorado 3020 035 50(4850) -3038c New Mexico 3063 051 49(4850) -2938c

Connecticut 3747 042 43(3744) -1361c New York 3894 019 39(3742) -1021c

Delaware 4884 094 14(1118) 1261c North Carolina 4901 030 13(1216) 1301c

DC 3889 115 40(3244) -1035c North Dakota 3952 099 37(3344) -889c

Florida 4244 018 30(2834) -215 Ohio 5171 027 11(1113) 1922c

Georgia 4620 031 19(1723) 651c Oklahoma 5570 051 06(0510) 2842c

Hawaii 3160 062 48(4750) -2715c Oregon 4233 043 31(2734) -241Idaho 3612 065 44(4346) -1671c Pennsylvania 4521 024 25(2027) 423Illinois 4635 026 18(1723) 686c Rhode Island 4827 088 17(1324) 1130c

Indiana 5345 039 09(0610) 2322c South Carolina 4884 042 15(1218) 1260c

Iowa 4557 049 23(2028) 507c South Dakota 4287 093 29(2337) -115Kansas 4591 054 21(1827) 585c Tennessee 5697 039 05(0305) 3136c

Kentucky 6772 052 01(0101) 5615c Texas 3896 018 38(3640) -1016c

Louisiana 5362 047 08(0610) 2363c Utah 1949 042 51(5151) -5507c

Maine 5156 076 12(1015) 1888c Vermont 4473 107 26(1529) 313Maryland 4154 037 34(2836) -422 Virginia 4402 032 27(2229) 149Massachusetts 4208 033 33(2834) -297 Washington 4059 033 36(3237) -641c

Michigan 4854 029 16(1418) 1191c West Virginia 5880 069 03(0205) 3557c

Minnesota 3880 036 41(3743) -1053c Wisconsin 4297 036 28(2734) -094Mississippi 5742 059 04(0205) 3239c Wyoming 3527 108 46(4146) -1867c

Missouri 5408 039 07(0610) 2468c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5383 008

High Five StatesKentucky 8667 090 01(0101) 6099c

Mississippi 8030 108 02(0203) 4916c

Arkansas 7852 101 03(0205) 4586c

West Virginia 7574 119 04(0307) 4069c

Tennessee 7510 069 05(0306) 3950c

Low Five StatesWyoming 3982 170 47(4249) -2603c

California 3832 022 48(4649) -2882c

New Mexico 3628 084 49(4750) -3261c

Colorado 3396 056 50(4950) -3691c

Utah 2389 069 51(5151) -5562c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7370 079 06(0406) 3690c Montana 4573 126 42(3746) -1505c

Alaska 5305 222 24(1740) -146 Nebraska 5250 107 27(2235) -248Arizona 4150 048 45(4347) -2291c Nevada 5114 089 31(2437) -500c

Arkansas 7852 101 03(0205) 4586c New Hampshire 5258 123 26(2237) -233California 3832 022 48(4649) -2882c New Jersey 4593 047 40(3742) -1468c

Colorado 3396 056 50(4950) -3691c New Mexico 3628 084 49(4750) -3261c

Connecticut 4389 069 43(4044) -1847c New York 4746 032 37(3641) -1185c

Delaware 5945 157 16(1222) 1043c North Carolina 6502 053 11(1013) 2077c

DC 4718 198 39(2544) -1237c North Dakota 5056 168 32(2341) -607c

Florida 5215 029 28(2431) -313 Ohio 6459 047 13(1114) 1998c

Georgia 6216 057 15(1316) 1547c Oklahoma 7004 086 08(0710) 3011c

Hawaii 3985 103 46(4449) -2599c Oregon 4827 069 36(3140) -1033c

Idaho 4194 104 44(4247) -2209c Pennsylvania 5711 040 21(1723) 609c

Illinois 5735 044 20(1723) 654c Rhode Island 5873 148 17(1526) 910c

Indiana 6841 066 09(0710) 2707c South Carolina 6492 074 12(1014) 2059c

Iowa 5805 084 19(1624) 783c South Dakota 5278 154 25(1835) -196Kansas 5591 089 22(1826) 386 Tennessee 7510 069 05(0306) 3950c

Kentucky 8667 090 01(0101) 6099c Texas 4982 031 34(2836) -746c

Louisiana 7061 083 07(0609) 3116c Utah 2389 069 51(5151) -5562c

Maine 6335 126 14(1117) 1767c Vermont 5130 172 30(1938) -470Maryland 5002 062 33(2737) -709c Virginia 5533 055 23(1926) 278Massachusetts 4949 055 35(2837) -808c Washington 4743 054 38(3440) -1189c

Michigan 5858 048 18(1619) 881c West Virginia 7574 119 04(0307) 4069c

Minnesota 4584 059 41(3843) -1485c Wisconsin 5175 059 29(2435) -388Mississippi 8030 108 02(0203) 4916c Wyoming 3982 170 47(4249) -2603c

Missouri 6733 066 10(0812) 2506c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 4337 005

High Five StatesKentucky 6772 052 01(0101) 5615c

Arkansas 5904 058 02(0205) 3612c

West Virginia 5880 069 03(0205) 3557c

Mississippi 5742 059 04(0205) 3239c

Tennessee 5697 039 05(0305) 3136c

Low Five StatesCalifornia 3216 013 47(4748) -2585c

Hawaii 3160 062 48(4750) -2715c

New Mexico 3063 051 49(4850) -2938c

Colorado 3020 035 50(4850) -3038c

Utah 1949 042 51(5151) -5507c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 5339 043 10(0610) 2309c Montana 4109 081 35(3243) -526c

Alaska 4600 138 20(1332) 607c Nebraska 4220 064 32(2737) -271Arizona 3529 030 45(4446) -1864c Nevada 4540 057 24(1727) 468Arkansas 5904 058 02(0205) 3612c New Hampshire 4558 076 22(1730) 509c

California 3216 013 47(4748) -2585c New Jersey 3832 028 42(3743) -1165c

Colorado 3020 035 50(4850) -3038c New Mexico 3063 051 49(4850) -2938c

Connecticut 3747 042 43(3744) -1361c New York 3894 019 39(3742) -1021c

Delaware 4884 094 14(1118) 1261c North Carolina 4901 030 13(1216) 1301c

DC 3889 115 40(3244) -1035c North Dakota 3952 099 37(3344) -889c

Florida 4244 018 30(2834) -215 Ohio 5171 027 11(1113) 1922c

Georgia 4620 031 19(1723) 651c Oklahoma 5570 051 06(0510) 2842c

Hawaii 3160 062 48(4750) -2715c Oregon 4233 043 31(2734) -241Idaho 3612 065 44(4346) -1671c Pennsylvania 4521 024 25(2027) 423Illinois 4635 026 18(1723) 686c Rhode Island 4827 088 17(1324) 1130c

Indiana 5345 039 09(0610) 2322c South Carolina 4884 042 15(1218) 1260c

Iowa 4557 049 23(2028) 507c South Dakota 4287 093 29(2337) -115Kansas 4591 054 21(1827) 585c Tennessee 5697 039 05(0305) 3136c

Kentucky 6772 052 01(0101) 5615c Texas 3896 018 38(3640) -1016c

Louisiana 5362 047 08(0610) 2363c Utah 1949 042 51(5151) -5507c

Maine 5156 076 12(1015) 1888c Vermont 4473 107 26(1529) 313Maryland 4154 037 34(2836) -422 Virginia 4402 032 27(2229) 149Massachusetts 4208 033 33(2834) -297 Washington 4059 033 36(3237) -641c

Michigan 4854 029 16(1418) 1191c West Virginia 5880 069 03(0205) 3557c

Minnesota 3880 036 41(3743) -1053c Wisconsin 4297 036 28(2734) -094Mississippi 5742 059 04(0205) 3239c Wyoming 3527 108 46(4146) -1867c

Missouri 5408 039 07(0610) 2468c

Table 1524Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5383 008

High Five StatesKentucky 8667 090 01(0101) 6099c

Mississippi 8030 108 02(0203) 4916c

Arkansas 7852 101 03(0205) 4586c

West Virginia 7574 119 04(0307) 4069c

Tennessee 7510 069 05(0306) 3950c

Low Five StatesWyoming 3982 170 47(4249) -2603c

California 3832 022 48(4649) -2882c

New Mexico 3628 084 49(4750) -3261c

Colorado 3396 056 50(4950) -3691c

Utah 2389 069 51(5151) -5562c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7370 079 06(0406) 3690c Montana 4573 126 42(3746) -1505c

Alaska 5305 222 24(1740) -146 Nebraska 5250 107 27(2235) -248Arizona 4150 048 45(4347) -2291c Nevada 5114 089 31(2437) -500c

Arkansas 7852 101 03(0205) 4586c New Hampshire 5258 123 26(2237) -233California 3832 022 48(4649) -2882c New Jersey 4593 047 40(3742) -1468c

Colorado 3396 056 50(4950) -3691c New Mexico 3628 084 49(4750) -3261c

Connecticut 4389 069 43(4044) -1847c New York 4746 032 37(3641) -1185c

Delaware 5945 157 16(1222) 1043c North Carolina 6502 053 11(1013) 2077c

DC 4718 198 39(2544) -1237c North Dakota 5056 168 32(2341) -607c

Florida 5215 029 28(2431) -313 Ohio 6459 047 13(1114) 1998c

Georgia 6216 057 15(1316) 1547c Oklahoma 7004 086 08(0710) 3011c

Hawaii 3985 103 46(4449) -2599c Oregon 4827 069 36(3140) -1033c

Idaho 4194 104 44(4247) -2209c Pennsylvania 5711 040 21(1723) 609c

Illinois 5735 044 20(1723) 654c Rhode Island 5873 148 17(1526) 910c

Indiana 6841 066 09(0710) 2707c South Carolina 6492 074 12(1014) 2059c

Iowa 5805 084 19(1624) 783c South Dakota 5278 154 25(1835) -196Kansas 5591 089 22(1826) 386 Tennessee 7510 069 05(0306) 3950c

Kentucky 8667 090 01(0101) 6099c Texas 4982 031 34(2836) -746c

Louisiana 7061 083 07(0609) 3116c Utah 2389 069 51(5151) -5562c

Maine 6335 126 14(1117) 1767c Vermont 5130 172 30(1938) -470Maryland 5002 062 33(2737) -709c Virginia 5533 055 23(1926) 278Massachusetts 4949 055 35(2837) -808c Washington 4743 054 38(3440) -1189c

Michigan 5858 048 18(1619) 881c West Virginia 7574 119 04(0307) 4069c

Minnesota 4584 059 41(3843) -1485c Wisconsin 5175 059 29(2435) -388Mississippi 8030 108 02(0203) 4916c Wyoming 3982 170 47(4249) -2603c

Missouri 6733 066 10(0812) 2506c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 5383 008

High Five StatesKentucky 8667 090 01(0101) 6099c

Mississippi 8030 108 02(0203) 4916c

Arkansas 7852 101 03(0205) 4586c

West Virginia 7574 119 04(0307) 4069c

Tennessee 7510 069 05(0306) 3950c

Low Five StatesWyoming 3982 170 47(4249) -2603c

California 3832 022 48(4649) -2882c

New Mexico 3628 084 49(4750) -3261c

Colorado 3396 056 50(4950) -3691c

Utah 2389 069 51(5151) -5562c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 7370 079 06(0406) 3690c Montana 4573 126 42(3746) -1505c

Alaska 5305 222 24(1740) -146 Nebraska 5250 107 27(2235) -248Arizona 4150 048 45(4347) -2291c Nevada 5114 089 31(2437) -500c

Arkansas 7852 101 03(0205) 4586c New Hampshire 5258 123 26(2237) -233California 3832 022 48(4649) -2882c New Jersey 4593 047 40(3742) -1468c

Colorado 3396 056 50(4950) -3691c New Mexico 3628 084 49(4750) -3261c

Connecticut 4389 069 43(4044) -1847c New York 4746 032 37(3641) -1185c

Delaware 5945 157 16(1222) 1043c North Carolina 6502 053 11(1013) 2077c

DC 4718 198 39(2544) -1237c North Dakota 5056 168 32(2341) -607c

Florida 5215 029 28(2431) -313 Ohio 6459 047 13(1114) 1998c

Georgia 6216 057 15(1316) 1547c Oklahoma 7004 086 08(0710) 3011c

Hawaii 3985 103 46(4449) -2599c Oregon 4827 069 36(3140) -1033c

Idaho 4194 104 44(4247) -2209c Pennsylvania 5711 040 21(1723) 609c

Illinois 5735 044 20(1723) 654c Rhode Island 5873 148 17(1526) 910c

Indiana 6841 066 09(0710) 2707c South Carolina 6492 074 12(1014) 2059c

Iowa 5805 084 19(1624) 783c South Dakota 5278 154 25(1835) -196Kansas 5591 089 22(1826) 386 Tennessee 7510 069 05(0306) 3950c

Kentucky 8667 090 01(0101) 6099c Texas 4982 031 34(2836) -746c

Louisiana 7061 083 07(0609) 3116c Utah 2389 069 51(5151) -5562c

Maine 6335 126 14(1117) 1767c Vermont 5130 172 30(1938) -470Maryland 5002 062 33(2737) -709c Virginia 5533 055 23(1926) 278Massachusetts 4949 055 35(2837) -808c Washington 4743 054 38(3440) -1189c

Michigan 5858 048 18(1619) 881c West Virginia 7574 119 04(0307) 4069c

Minnesota 4584 059 41(3843) -1485c Wisconsin 5175 059 29(2435) -388Mississippi 8030 108 02(0203) 4916c Wyoming 3982 170 47(4249) -2603c

Missouri 6733 066 10(0812) 2506c

Table 1525Cancer of the Lung and Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 5 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 3539 006

High Five StatesKentucky 5349 062 01(0101) 5113c

West Virginia 4573 084 02(0204) 2920c

Oklahoma 4463 062 03(0209) 2610c

Missouri 4403 048 04(0208) 2440c

Arkansas 4373 068 05(0213) 2355c

Low Five StatesCalifornia 2750 016 47(4648) -2231c

Colorado 2734 045 48(4649) -2277c

New Mexico 2618 064 49(4850) -2604c

Hawaii 2503 075 50(4950) -2930c

Utah 1585 051 51(5151) -5521c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 3821 049 21(1524) 795 Montana 3741 107 23(1739) 570Alaska 3993 176 17(0231) 1280c Nebraska 3437 078 36(2843) -290Arizona 3015 038 46(4346) -1482c Nevada 4061 073 14(0620) 1474c

Arkansas 4373 068 05(0213) 2355c New Hampshire 4049 098 15(0624) 1439c

California 2750 016 47(4648) -2231c New Jersey 3295 034 38(3543) -692Colorado 2734 045 48(4649) -2277c New Mexico 2618 064 49(4850) -2604c

Connecticut 3285 053 40(3142) -718 New York 3287 023 39(3542) -715Delaware 4091 115 12(0321) 1558c North Carolina 3709 035 24(2029) 478DC 3274 139 41(2446) -751 North Dakota 3129 121 44(3548) -1159c

Florida 3451 022 34(3037) -251 Ohio 4208 033 09(0614) 1889c

Georgia 3447 036 35(2938) -262 Oklahoma 4463 062 03(0209) 2610c

Hawaii 2503 075 50(4950) -2930c Oregon 3777 055 22(1627) 670Idaho 3132 083 43(3946) -1152c Pennsylvania 3651 029 27(2332) 314Illinois 3833 032 19(1623) 830 Rhode Island 4111 108 10(0322) 1614c

Indiana 4217 046 08(0414) 1914c South Carolina 3656 049 26(2031) 330Iowa 3606 060 29(2438) 187 South Dakota 3563 117 30(2143) 065Kansas 3823 067 20(1731) 800 Tennessee 4325 046 06(0312) 2218c

Kentucky 5349 062 01(0101) 5113c Texas 3062 022 45(4145) -1350c

Louisiana 4067 055 13(0818) 1490c Utah 1585 051 51(5151) -5521c

Maine 4236 093 07(0318) 1968c Vermont 3963 138 18(0326) 1196c

Maryland 3538 045 32(2335) -005 Virginia 3539 038 31(2535) -002Massachusetts 3692 041 25(2030) 430 Washington 3529 042 33(2436) -030Michigan 4093 036 11(0918) 1562c West Virginia 4573 084 02(0204) 2920c

Minnesota 3356 046 37(3543) -519 Wisconsin 3645 045 28(2132) 298Mississippi 4046 066 16(0821) 1432c Wyoming 3185 142 42(2847) -1001c

Missouri 4403 048 04(0208) 2440c

Table 1526Cancer of the Lung And Bronchus (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

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100

1975 1985 1995 2005 20150

20

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 20150

20

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1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 20150

100

200

300

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1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

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60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 314786 112172 51962 27782 14327 7630 521029 534600 6435 541035

Males 143223 47327 21646 11459 5922 3048 229580 235174 3730 238904Females 171563 64845 30316 16323 8405 4582 291449 299426 2705 302131

Whiteb Both Sexes 264728 96906 45241 24266 12518 6914 443660 455745 2300 458045Males 119897 40327 18431 9735 5073 2729 193465 198360 1061 199421Females 144831 56579 26810 14531 7445 4185 250195 257385 1239 258624

Blackb Both Sexes 35671 10846 4793 2496 1370 523 55175 56271 210 56481Males 16502 4950 2259 1163 613 225 25487 25996 109 26105Females 19169 5896 2534 1333 757 298 29688 30275 101 30376

Asian Both Sexes 10982 3155 1442 + + + 16563 + + +Pacific Males 5381 1494 685 + + + 8063 + + +Islanderc Females 5601 1661 757 + + + 8500 + + +

Hispanicd Both Sexes 12090 4086 1939 + + + 19382 + + +Males 5530 1751 867 + + + 8720 + + +Females 6560 2335 1072 + + + 10662 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01364 00002 00004 00017 00063 00246 01191 03639 08598 09193 01270

Males 01227 00002 00005 00016 00057 00214 01025 03558 08595 10278 01274Females 01498 - 00003 00018 00070 00278 01351 03712 08600 08535 01276

Whitec Both Sexes 01487 00002 00005 00020 00064 00251 01168 03669 09037 09620 01311Males 01301 - 00005 00017 00054 00214 00990 03458 08749 10439 01277Females 01672 - 00005 00023 00073 00289 01345 03867 09280 09115 01350

Blackc Both Sexes 01161 - - 00013 00068 00266 01651 04692 08846 07773 01369Males 01117 - - 00018 00068 00261 01409 05314 09925 10044 01529Females 01201 - - - 00068 00271 01863 04204 08092 06640 01273

Asian Both Sexes 00998 - - 00007 00058 00222 00974 02774 06094 07516 00969Pacific Males 01009 - - - 00052 00197 00952 03019 07015 09421 01098Islanderc Females 00988 - - - 00063 00244 00992 02574 05374 06339 00879

Hispanicd Both Sexes 00360 - - 00016 00041 00132 00498 01575 04191 04979 00619Males 00319 - - 00013 00036 00124 00425 01475 04455 05986 00650Females 00401 - - 00019 00046 00140 00569 01661 03993 04369 00603

Table 1527Cancer of the Lung And Bronchus (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 481 227250 997 184947 997 25930 998 14663 998 825 995 13448 995

Small cell (80028041-8045) 61 29501 129 25602 138 2650 102 1047 71 119 144 1416 105

Non-small cell 406 191281 839 154148 831 22467 864 13215 899 676 815 11578 856

Squamous and 114 52928 232 43862 236 6370 245 2265 154 246 297 2579 191

transitional celld

Adenocarcinomae 231 109146 479 86323 465 12597 485 9447 643 322 388 7038 521

Large cellf 07 3407 15 2781 15 453 17 155 11 - - 166 12

Non-small cell carcinomag 29 13900 61 11060 60 1915 74 798 54 65 78 889 66

Other specified carcinomash 25 11900 52 10122 55 1132 44 550 37 36 43 906 67

Carcinoma NOSi 14 6468 28 5197 28 813 31 401 27 30 36 454 34

Sarcomaj 01 419 02 350 02 41 02 20 01 - - 53 04

Other specified typesk 00 220 01 184 01 24 01 - - - - 17 01

Total 483 227889 1000 185481 1000 25995 1000 14694 1000 829 1000 13518 1000

Table 1528

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 559 118319 997 95050 997 14277 997 8116 998 429 995 7041 994

Small cell (80028041-8045) 67 14553 123 12399 130 1349 94 698 86 63 146 734 104

Non-small cell 474 100099 843 79766 836 12422 868 7174 882 348 807 6036 852

Squamous and 158 32875 277 26988 283 4001 279 1625 200 142 329 1633 231

transitional celld

Adenocarcinomae 245 52016 438 40576 425 6467 452 4627 569 142 329 3384 478

Large cellf 09 1930 16 1543 16 275 19 100 12 - - 102 14

Non-small cell carcinomag 37 7904 67 6175 65 1133 79 529 65 39 90 509 72

Other specified carcinomash 25 5374 45 4484 47 546 38 293 36 21 49 408 58

Carcinoma NOSi 18 3667 31 2885 30 506 35 244 30 18 42 271 38

Sarcomaj 01 252 02 214 02 22 02 - - - - 33 05

Other specified typesk 01 131 01 107 01 16 01 - - - - - -

Total 561 118702 1000 95371 1000 14315 1000 8135 1000 431 1000 7081 1000

Table 1529

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Males by Race

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Squamous and transitional cell includes histologies 8051-8052 8070-8076 8078 8083-8084 8090 8094 8120 8123e Adenocarcinoma includes histologies 8015 8050 8140-8141 8143-8145 8147 8190 8201 8211 8250-8255 8260 8290 8310

8320 8323 8333 8401 8440 8470-8471 8480-8481 8490 8503 8507 8550 8570-8572 8574 8576f Large cell includes histologies 8012-8014 8021 8034 8082g Non-small cell carcinoma includes histology 8046h Other specified carcinomas includes histologies 8003-8004 8022 8030 8031-8033 8035 8200 8240-8241 8243-8246 8249 8430

8525 8560 8562 8575i Carcinoma NOS includes histologies 8000-8001 8010-8011 8020 8230j Sarcoma includes histologies 8680 8711 8800-8805 8810-8811 8815 8824 8830 8840 8852 8855 8890-8891 8894-8895

8900-8902 8910 8920-8921 8940 8990 9040-9041 9043 9120 9130 9133 9150 9180 9220 9231 9240 9251 9473 95409560 9580

k Other specific types includes melanomas and is defined as histologies 8580 8650 8720-8790 8933 8963 8972-8973 8980-89829064-9065 9070 9080 9084-9085 9100 9260 9364 9503 9530

Note For this analysis the following histolgies were classified as metastases of another primary site and not included 8005 81308146 8170 8231 8247 8263 8312 8340-8341 8350 8441 8460 8500-8501 8524 8530 8551 8581 8585 8710 8772 88068850 8854 8896 8935 9015 9042 9071 9101 9181 9370 9500 9561 9581

- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Rate Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 422 108931 998 89897 998 11653 998 6547 998 396 995 6407 995

Small cell (80028041-8045) 57 14948 137 13203 147 1301 111 349 53 56 141 682 106

Non-small cell 354 91182 835 74382 825 10045 860 6041 921 328 824 5542 861

Squamous and 79 20053 184 16874 187 2369 203 640 98 104 261 946 147

transitional celld

Adenocarcinomae 221 57130 523 45747 508 6130 525 4820 735 180 452 3654 568

Large cellf 06 1477 14 1238 14 178 15 55 08 - - 64 10

Non-small cell carcinomag 23 5996 55 4885 54 782 67 269 41 26 65 380 59

Other specified carcinomash 25 6526 60 5638 63 586 50 257 39 - - 498 77

Carcinoma NOSi 11 2801 26 2312 26 307 26 157 24 - - 183 28

Sarcomaj 01 167 02 136 02 19 02 - - - - 20 03

Other specified typesk 00 89 01 77 01 - - - - - - - -

Total 423 109187 1000 90110 1000 11680 1000 6559 1000 398 1000 6437 1000

Table 1530

Cancer of the Lung and Bronchus (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Females by Race

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

30

60

90

120

150

180

1975 1985 1995 2005 20150

30

60

90

120

150

180

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus by Race and Sex

a

Figure 151

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

US Mortality APC2012-15 = -39

SEER Incidence APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

US Mortality APC2013-15 = -54

SEER Incidence APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

US Mortality APC2013-15 = -47

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 20150

20

40

60

80

100

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Under 65 Years of Age by Race and Sex

a

Figure 152

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1987-15 = -34Observed 1987-15 = -34

US Mortality APC2002-15 = -36

SEER Incidence APCsDelay Adj 2003-15 = -51Observed 2003-15 = -52

US Mortality APC2004-15 = -49

SEER Incidence APCsDelay Adj 2002-15 = -26Observed 2002-15 = -26

US Mortality APC2003-15 = -27

SEER Incidence APCsDelay Adj 1986-15 = -17Observed 1988-15 = -19

US Mortality APC2005-15 = -35

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

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500

600

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1975 1985 1995 2005 20150

100

200

300

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1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

500

600

700

800

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 20150

100

200

300

400

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Lung and Bronchus Ages 65 and Over by Race and Sex

a

Figure 153

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = -30Observed 2009-15 = -33

US Mortality APC2010-15 = -36 SEER Incidence APCs

Delay Adj 1997-15 = -21Observed 1997-15 = -22

US Mortality APC2012-15 = -45

SEER Incidence APCsDelay Adj 2006-15 = -12Observed 2007-15 = -15

US Mortality APC2009-15 = -22

SEER Incidence APCsDelay Adj 2006-15 = -14Observed 2006-15 = -16

US Mortality APC2013-15 = -46

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

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150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

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1975 1985 1995 2005 201550

75

100

125

150

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 20150

10

20

30

40

50

60

70

80

90

100

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Lung and Bronchus Both Sexes

Figure 154

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

125

150

175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

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60

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1975 1985 1995 2005 20150

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50

60

70

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

120

1975 1980 1985 1990 1995 2000 2005 2010 2015

Male Delay-Adjusted IncidenceMale Delay-Adjusted Incidence

Male MortalityMale Mortality

Female Delay-Adjusted IncidenceFemale Delay-Adjusted Incidence

Female MortalityFemale Mortality

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence amp US Death Rates

1975-2015 All Races By Sex

Figure 155

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of DiagnosisDeath

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

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200

1975 1985 1995 2005 201550

75

100

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1975 1985 1995 2005 201550

75

100

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

40

50

60

70

1975 1985 1995 2005 20150

10

20

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60

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1975 1985 1995 2005 20150

10

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

20

40

60

80

100

120

140

160

180

1975 1980 1985 1990 1995 2000 2005 2010 2015

Black Male

White Male

Black Female

White Female

Cancer of the Lung amp BronchusSEER Delay-Adjusted Incidence 1975-2015

By Sex and Race

Figure 156

Source SEER 9 areas Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018National Cancer Institute

Rate per 100000

Year of Diagnosis

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

50

75

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200

1975 1985 1995 2005 201550

75

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1975 1985 1995 2005 201550

75

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

10

20

30

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60

70

1975 1985 1995 2005 20150

10

20

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1975 1985 1995 2005 20150

10

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

50

75

100

125

150

175

200

1975 1985 1995 2005 201550

75

100

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150

175

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1975 1985 1995 2005 201550

75

100

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175

200

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Male by Race

aFigure 157

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2008-15 = -29Observed 2008-15 = -31

SEER 13 APCsDelay Adj 2008-15 = -30Observed 2008-15 = -32

SEER 9 APCsDelay Adj 2008-15 = -28Observed 2009-15 = -33

SEER 13 APCsDelay Adj 2008-15 = -29Observed 2009-15 = -34

SEER 9 APCsDelay Adj 1998-15 = -29Observed 1998-15 = -30

SEER 13 APCsDelay Adj 1992-15 = -27Observed 2009-15 = -48

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

0

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 20150

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1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Lung and Bronchus Female by Race

aFigure 158

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2006-15 = -15Observed 2007-15 = -18

SEER 13 APCsDelay Adj 2006-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2007-15 = -15Observed 2007-15 = -17

SEER 13 APCsDelay Adj 2007-15 = -17Observed 2007-15 = -20

SEER 9 APCsDelay Adj 2006-15 = -18Observed 2006-15 = -19

SEER 13 APCsDelay Adj 2005-15 = -17Observed 2005-15 = -19

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival

Figure 159

Cancer of the Lung and Bronchus5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Trends in SEER Incidence (Small Cell and Non-small Cell Cancer)
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Incidence Rates (Small Cell Cancer)
• Annual Incidence Rates (Non-Small Cell Cancer)
• Annual Death Rates
• Incidence and Mortality Rates by Age
• Incidence Rates by Age (Small Cell and Non-Small Cell Cancer)
• 5-year Relative and Period Survival
• 5-year Relative and Period Survival (Small Cell Cancer)
• 5-year Relative and Period Survival (Non-Small Cell Cancer)
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying
• Risk of DevelopingDying
• Risk of DevelopingDying
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology Both Sexes
• Case Distribution by Histology Males
• Case Distribution by Histology Females
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages lt65)
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex (Ages 65+)
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - SEER Delay Adjusted Incidence and US Death Rates by Sex
• Graph - SEER Delay Adjusted Incidence by Sex and Race
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
• Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
• Graph - 5-Year SEER Conditional Relative Survival