Mekanisme Zat Penyebab Gangguan

Alcohol

At high dose level alcohol disrupts the neurotransmissio system

Inhibits catechoaminergic systems and inhibits excitatry amino acids

Als activates tha GABAergic system

Do not feel depressed ( can’t feel their depression)

Symptoms of anxiety occurs after the withdrawal/stop the alchol

caffeine

Absorb from digestive tract without being broken down

Rapidly distributed throughout the tissue of the body by means of the blood stream, then reaches the brain

Increase the secretion of norepinefhrine (neurotransmitter thad associated with te so-called fight or flight stress response)

Increase the activity of neuron ( competitive antagonism at adenosine receptors)

Anxiety/panic attack!!

nicotine

After cigarette is smoked. Nicotine-rich blood passes from the lungs to the brain within 7 seconds

Binding to nicotinic acetylcholine receptrs

Decrease MAO’s activities

Increase levels of monoaminergic neurotransmitter such as dopamine, NE and serotonin

Anxiety/panic attack after the witdrawal or Stop the drugs

amphetamine

cocaine