Presented at

Guy's and St Thomas' Hospital London, September 3-4, 2019

Sponsored by CRRT Inc and Guy's and St Thomas' Hospital LondonThe conference provides a comprehensive review of advances in clinical care, research and technology in critical care medicine with a focus on the kidney and renal support techniques during critical illness. During the conference, a selection of highlights of the 2019 CRRT & AKI Conference in San Diego will be presented. The conference is designed to facilitate interdisciplinary interactions among caregivers involved in the management of patients in the ICU. Physicians, nurses, pharmacists and other allied health care workers have opportunities to learn from each other and to interact with the international faculty through focused panel discussions and workshops.

Please join us for this educational review of highlights from the 2019 conference.

Selections from AKI & CRRT conference 2019SAN DIEGO, CALIFORNIA

Critical Care Nephrology and CRRT Highlights: Selections from the 24th International AKI and CRRT Conference 2019

Contact: Rudo.Mupambawahle@gstt.nhs.uk

Registration: https://www.eventbrite.co.uk/e/highlights-of-crrt-2019-tickets-64425527487aff=ebdssbdestsearch

Approval for 12 CPD credits has been applied for from the Federation of the Royal Colleges of Physicians UK

DAY 2 4TH SEPTEMBER 2019

08:30 - 09:40 SESSION 4: RENAL REPLACEMENT THERAPY 08:30 - 08:50 Combining RRT and ECMO - Andy Shaw08:50 - 09:10 RRT in liver patients - Mitra Nadim09:10 - 09:40 Quality metrics in RRT - Sean Bagshaw

09:40 - 10:00 Coffee Break

10:00 - 11:30 WORKSHOPS (Participants can select one) Workshop 3: How to use novel Biomarkers in clinical practice - Patrick Murray and Claudio Ronco

Workshop 4: Effective comunication for shared decision making - Gita Mehta and Michael Wise

11:30 - 13:00 SESSION 5: NEW DEVELOPMENTS IN AKI11:30 - 11:50 New therapies for AKI - Patrick Murray 11:50 - 12:10 Hepatorenal syndrome - does it exist? - Mitra Nadim 12:10 - 12:30 Perioperative haemodynamic management to prevent AKI

- Andy Shaw12:15 - 12:45 Critical Care Nephrology Literature - Patrick Murray

12:45 Closing remarks and feedback13:00 Adjourn

Faculty Organisers: Professor Ravindra Mehta, University of California San Diego, USA Dr Marlies Ostermann, Guy’s & St Thomas’ Hospital, London, UK

International FacultyProfessor Sean Bagshaw, University of Alberta, Edmonton, Canada Professor Lui Forni, University of Surrey, UKDr Katie Lane, Guy's & St Thomas' Hospital, London, UK Professor Gita Mehta, University of California San Diego, USA Professor Patrick Murray, University College Dublin, Dublin, Ireland Professor Mitra Nadim, University of Los Angeles, USADr John Prowle, Royal London Hospital, London, UKProfessor Claudio Ronco, University of Padova, Padova, Italy Professor Andy Shaw, University of Alberta, Edmonton, CanadaDr Andy Slack, Guy's & St Thomas' Hospital, London, UKMrs Linda Tovey, Guy's & St Thomas' Hospital, London, UKProfessor Jean-Louis Vincent, Erasme University, Brussels, Belgium Dr Michael Wise, London, UK

DAY 1 3rd SEPTEMBER 2019

08.00 REGISTRATION

09.00 WELCOME

09.10 - 10:30 SESSION 1: ORGAN DYSFUNCTION IN THE CRITICALLY ILL PATIENT: EMERGING CONCEPTS 09.10 - 09.30 Treatment of septic shock - Jean Louis Vincent 09:30 - 09:50 Fluid management in AKI - John Prowle09:50 - 10:10 Combined cardiac and renal failure - Claudio Ronco 10:10 - 10:30 Vasoplegic shock: definition & pathophysiology - Lui Forni

10:30 - 11:00 Coffee Break

11:00 - 11.20 SESSION 2: AKI IN SPECIAL PATIENT GROUPS 11:00 - 11:20 AKI in sepsis - Jean-Louis Vincent 11:20 - 11:40 AKI in trauma - John Prowle 11:40 - 12:00 Clinical prediction rules for AKI: Can we improve?

- Lui Forni12:00 - 12:20 AKI in cancer patients - Marlies Ostermann

12.30 - 13:30 Lunch

13:30 - 15:00 WORKSHOPS (Participants can select one) Workshop 1: Starting, transitioning and stopping RRT - Ravi Mehta and Sean Bagshaw Workshop 2: Understanding the CRRT machine (Hands-on session) Marlies Ostermann, Katie Lane, Linda Tovey and Andy Slack

15:00 - 15:30 Coffee Break

15:30 - 17:00 SESSION 3: CHALLENGES AND CONTROVERSIES IN AKI MANAGEMENT 15:30 - 15:50 Haemodynamic management in AKI - Sean Bagshaw 15:50 - 16:10 Renal functional reserve: A target for intervention? - Claudio Ronco16:10 - 16:30 Ventilator induced AKI - Sean Bagshaw16:30 - 16.50 Role of novel AKI biomarkers - Patrick Murray 16.50 - 17.00 Questions and answers

17:00 Adjourn