PharmAfrican / BDA Foundation Tandem: A Benefit sharing food crisis solution for

African value-added agriculture

Carole RobertCEO PharmAfrican

Chairman BDA Foundation

African HIGHLY nutritive Ingredients

time for changesMore than 90% of food supplements supplied to Africa are grown, processed and packaged OUT OF AFRICA and formulated, manufactured, transported and distributed by non African

companies This means:• the value addition remains Out of Africa• the employment benefits remains Out of Africa• the research and development benefits remain Out of Africa• the technical knowledge remains Out of Africa• the management skills remains Out of Africa

Good Hygiene Practices-Good Agricultural and Collection Practices- Designed to control hazards related to safety and quality of raw material Good Manufacturing Practices - Designed to control hazards related to personnel and the food manufacturing environment, creating conditions that are favourable to the production of safe food products.HACCP systems and HACCP-based systems - Designed to control hazards directly related to the food being processed or the manufacturing process.Codex Alimentarus- Designed to allow the traceability of products

It is a question of people, of creating jobs, a question of dignity

A Quality Control issue:Raise the capability to meet QC criteria for trade

Implement Quality Assurance Systems

A question of GACP cultivation quality control

A question of post harvesting quality control

People are capable. They want jobs.

They want trade and economic development

Business Model based on Blended value , benefit sharing and triple bottom line(financial, social and environmental)

And

A Canadian biopharma created in 2006

A Canadian NGO founded in 2006

Actively taking action NOW, with African partners to deliver an African solution to food security

Botany

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Farming& Harvesting

Licence and alliance

Manufacturing Marketing & Commercialization

Licence and alliance

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Research & Development

PharmAfri-Can

1. GACP Cultivation 2. Clinical Data 3. GMP production

Implement TOGHETER solutions based on QUALITY CONTROL and address 3 major obstacles for an African food solution:

• Qualtity control cultivation (GACP, HACCP)• Quality control conditionning and processing (GMP)• Improved clinical data on safety and efficiency

Promotion and the development of medicinalplant agriculture in conformity with the standards of the global agri-food and pharmaceutical industry as guided by the framework provided by the World HealthOrganization.(GACP).

Good agricultural practicesGood harvesting practices

Raw material conditioningMedicinal plants conservationEnvironmental conservation

BDA’s OBJECTIVES: creation of an African industry

capable to meet international standards

The BDA Foudation’s focus is to promote the production of quality African medicinal plant products directed toward high-value market sectors.

•Jesuits of the Central African Province•World Wildlife Fund (WWF) in DRC•Prince Albert II of Monaco Foundation•Lundin For Africa•African Association for Medicinal Plants Standards (AAMPS)

Medicinal plants farming and marketing

ENTREPRENEURSHIP

Educational Program in Biotechnology and Medicinal

Plant CultivationACADEMIC TRAINING

WHOMedicinal Plants

Cultivation Protocol

AGRO ENTERPRISESFunds to facilitate Financial Credit

BIODIVERSITYLaboratory / Observatory

Protection of African Plants Heritage

Sensitizationand

Education in Africa

Good agricultural patrices Training

PRACTICAL TRAINING

Collaboration betweenBiotech Companies

And African Agricultural Enterprises

Scientific Collaboration and Transfer of

Know-How

Training in plant cultivation, harvesting, post conditionning, marketing ad exporting

3 phases, 3 years, $3Millions, 30 candidates/year – half women

• Conserve African biodiversity through urgent and concerted action for the protection of tropical forests;

• Promote equitable benefit sharing of these rich resources

• Support rural communities and their partners in the production and marketing of medicinal plants

• Encourage alliances and partnerships

• Contribute directly to the development of an African Pharmacopeia

• Support socio-economic projects according to sustainable development issues

ISSUES AND VALUES

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PharmAfrican Mission & Product Strategy-

PharmAfrican is a Biopharma Company developing therapeutic and nutritional product applications from African Medicinal Plants. Based on scientific cooperation with Jesuit, African and North American scientists, universities and laboratories, PharmAfrican is developing :

1. Botanical Drug (according to the US Botanical guideline):1. anti-inflammatory, 2. metabolic disorder involving diabetes, obesity, hypertension 3. and oncology.

2. Functional food and dietary supplements for the North American, European, African and other development countries consumer market

Institutional feeding programmes in Africa

Moringa Superfood program :a promissing beginning

PharmAfrican’s present efforts are focused on developing high quality reliable supplies of

Moringa food complements but the company is already working on a pipeline of high

nutrition African food products which can be used either alone or in combination as

nutritional supplements

• African eggplant ( Solanum aethiopicum)

• African spinach ( Amaranth species)

• African Winged Bean (Psophocarpus scandens)

• Bitterleaf ( Vernonia amygdalina)- see sweet bitterleaf also

• Cowpea ( Vigna unguiculata)

• Eru ( Gnetum Africanum)& ( Gnetum buchholzianum)

• Ethiopian Kale ( Brassica carinata)

• Jews Mallow – Krin Krin ( Corchorus olitorius)

• Jugo Bean – Bambara groundnut (Vigna subterranea)

• Lablab ( Lablab purpureus)

• Lagos Spinach ( Celosia argentea)

• Marama bean - Tylosema esculentum

• Pidgeon Pea (Cajanus Cajan)

Moringa—a Natural Fusion of Nutrients

• 46 Antioxidants• 36 Anti-Inflammatories• Omegas 3, 6 and 9• 20 Essential Amino Acids• Including 9 Essential Amino Acids

our bodies don’t produce

Moringa can be grown under carefully controlled conditions

Moringa nutritional dataSource: Tree for Life 2007

Moringa for children

“For a child aged 1-3, a 100 g serving of fresh cooked leaves would provide all his daily requirements of calcium, about 75% of his iron and half his protein needs, as well as important amounts of potassium, B vitamins, copper and all the essential amino acids. As little as 20 grams of leaves would provide a child with all the vitamins A and C he needs."

Lowell Fuglie Moringa oleifera: Natural Nutrition for the Tropics. ECHO 2008

% of Recommended Daily Allowance (RDA) of various nutrients for nursing mothers given 6 spoons (about 50 g) of moringa leaf powder daily. % of Allowance for a 1-3

year old child with 1 spoon x 3 daily (about 25g)

Mother Child

Daily dose 50 g 25 g

Protein: 21 % 42 %

Calcium 84 % 125 %

Magnesium 54 % 61 %

Potassium: 22 % 41 %

Iron: 94 % 71 %

Vitamin A: 143 % 272 %

Source: Lowell Fuglie 2008

Moringa as key component in Weaning Foods ?

Baby formulas proposed at the International MoringaConference in Ghana 2006.(designed for 6 month - 2 year old partially weaned children)

Moringa is already used as a nutrition supplement in Africa

• CWS, Senegal

• Word Vision, Mauritania

• Binga Trees Trust,Zimbabwe

• International Eye Foundation, Malawi

• Presbyterian Church, DR Congo

• L’Occitane Foundation, Burkina Faso

• Moringa Association of Ghana, Ghana

Beside GACP and GMP, still need more dataInternational agencies argue that there is little or no information about

the a) safety b) nutritional efficacy of African nutritious foods.

Need for a strong commitment for North/South universities scientific cooperation to undertake nutritional studies

• Any allergic reactions and food ingredient related illness

• Measure nutritional status of a group of subjects with and without the ingredient

• Measure the nutritional status of a sample group against similarimported ingredients

• Undertake similar comparisons on finished formulations

BDA can contribute to local nutrition surveys in the rural villages where we are implementing GACP production.

Agronomic and Environmental benefits of Moringa

• Can be grown as a forest tree or fast growing crop

• Can be grown at different altitudes

• Can be grown on different soils

• Can be grown as a plantation crop or on small farm plots

• Easy to cultivate and harvest

• Can be a monocrop or intercropped

• Is a drought resistant crop

• Protect the soil again erosion

• Offer opportunities for mechanisation

Social and Economic Benefits of local production

• Low cost source of protein and vitamins and minerals

• Suitable for both humans and animals

• Multipurpose uses for food, medicine and household use

• Can be grown equally well by small farmers as large farmers

• Offer considerable opportunities for value added products

• A cross cultural crop used in Africa, Asia and Latin America

How BDA producers benefit from GACPs

• Identify critical steps in production process

• Minimise risk of production failures

• Win or retain a business customer

• Promote sustainability of supply

• Minimise the risk of quality failures

• Minimise the risk of pollution

• Increase yields

• Prevent pesticide /fungicide residues

• Ensure proper documentation of crop cycle

• Build up long term QC/QA system

Benefits of PharmAfrican Moringa Programme

• Local income and employment to rural people

PharmAfrican’s strategy is to grow all its food supplements in Africa. Some of

this production will be on controlled plantations while others will be using closely

supervised contract growers. In both cases major income and employment

opportunities for local people will arise as well as supplying high quality ,

nutrition rich food materials

• Value addition benefits for local manufacturers

PharmAfrican’s strategy is to manufacture its food supplements in Africa.

Products will be made to international standards using raw materials grown under

GAP conditions. Thus value addition of manufacture will remain in Africa

• Reduce need for foreign exchange

By encouraging local production and processing PharmAfrican will help conserve

value foreign exchange presently used to by nutrition supplements and baby foods

Benefits of PharmAfrican Moringa Programme

• Training and Technology Transfer benefits for Africa

PharmAfrican is establishing a rigorous training and technology transfer programme

for growers and processors. This strategy will hence help build a cadre of locally

trained staff and know how needed to multiply the programme throughout Africa

• Self Sufficiency

PharmAfrican’s strategy is to make Africa eventually self sufficient in its food

supplement needs so that Governments in the region no longer need to rely on

outside aid to satisfy their nutrition needs

• Reduces transport costs (carbon footprint)

By encouraging local production and processing PharmAfrican will reduce transport

costs ( and Co2 emissions) needed to ship imported food supplements to Africa

Moringa powder can be processed in AfricaPictures: A small unit in Senegal : CRS/ASREAD

Asian Vegetable Research Centre (AVRDC) in 2003 published a detailed cultivation manual for Moringa

Moringa Oleifera has been chosen by AAMPS as one of the 52 plants selected for inclusion in the first African Herbal

Pharmacopoeia to be published in 2008