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Building a Healthy Boston Tuberculosis Impact in Boston Residents: 2012 BOSTON PUBLIC HEALTH COMMISSION Infectious Disease Bureau Communicable Disease Control Division

Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

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Page 1: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

Tuberculosis Impact in Boston Residents: 2012

BOSTON PUBLIC HEALTH COMMISSIONInfectious Disease Bureau

Communicable Disease Control Division

Page 2: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Number of TB Cases: Boston, 1995-2012

93 8779

8977 82 75

67 64 7057 61

4961 57 58

44 41

0

20

40

60

80

100

120

140

160

180

200

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Num

ber o

f cases

Page 3: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Incidence of TB: Boston, 2000-2012

13.912.7

11.4 10.911.9

9.7 10.48.3

10.4 9.7 9.8

7.1 6.6

02468101214161820

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Rate per 100

,000

Page 4: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Incidence of TB by Gender: Boston, 2010-2012

0

2

4

6

8

10

12

2010 2011 2012

Rate per 100

,000

Male Female

Page 5: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Percent of Reported TB Cases by Age Group: Boston, 2010-2012

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

< 25 years 25‐44 years 45‐64 years > 64 years

Percen

t

2010 2011 2012

Results may not equal 100% due to rounding

Page 6: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Incidence of TB by Age Group:Boston, 2010-2012

0

5

10

15

20

25

30

2010 2011 2012

Rate per 100

,000

< 20 years 20‐29 years 30‐39 years 40‐49 years 50‐59 years 60‐69 years >= 70 years

Page 7: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Percent of Reported Tuberculosis Cases by Race/Ethnicity: Boston, 2010-2012

0%

10%

20%

30%

40%

50%

60%

2010 2011 2012

Percen

t

White Black Hispanic Asian Other

Results may not equal 100% due to rounding

Page 8: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Incidence of TB by Race/Ethnicity: Boston, 2010-2012

05101520253035404550

2010 2011 2012

Rate per 100

,000

White Black Hispanic Asian Other

Page 9: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Incidence of TB Among the Homeless:Boston, 2010-2012

0

10

20

30

40

50

60

70

80

90

100

2010 2011 2012

Rate per 100

,000

Page 10: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

TB Cases by Birthplace: Boston, 2010-2012

0

20

40

60

80

100

2010 2011 2012

Percen

t

US Born Foreign Born

Results may not equal 100% due to rounding

Page 11: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Length of US Residence for Foreign Born TB Cases Prior to TB Diagnosis: Boston, 2010-2012

0

20

40

60

80

100

2010 2011 2012

Percen

t

<1 year 1‐5 years 6‐10 years > 10 years

Results may not equal 100% due to rounding

Page 12: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Region of Birth for TB Cases: Boston, 2012

0 5 10 15 20 25 30

Africa

Asia

Carribean

Central/South America

Europe

North America

Percent

Page 13: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Primary Site of TB Disease: Boston, 2012

64%

12%

7%17%

Pulmonary

Lymphatic

Pleural

Other

Page 14: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Sputum Smear and Culture Results for Cases with Primary Pulmonary TB: Boston, 2010-2012

0

5

10

15

20

2010* 2011** 2012***

Num

ber o

f  cases

Smear+/Culture+ Smear+/Culture‐ Smear‐/Culture+ Smear‐/Culture‐

*Sputum samples unavailable for 2 cases**Sputum samples unavailable for 3 cases***Sputum samples unavailable for 1 case

Page 15: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Drug Resistance in TB Cases:Boston, 2012

Number

One Drug Streptomycin 1

Page 16: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Completeness of HIV Testing* of TB Cases: Boston, 2010-2012

0102030405060708090

100

2010 2011 2012

Percen

t

*Includes cases with negative, positive and indeterminate HIV test results

Page 17: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Percent TB Cases with HIV Infection:* Boston, 2010-2012

0

2

4

6

8

10

2010 2011 2012

Percen

t

*Of those tested

Page 18: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

What health care sites are diagnosing and initiating TB treatment for Boston cases?

2011**N=42

2012*N=40

Diagnosing site Inpatient 29(66%) 31(77%)

Outpatient 15(34%) 9(22%)

Initial treatment site*

Inpatient 28(67%) 31(77%)

TB clinic 10(24%) 7(17%)

Hospital outpatient clinic

2(5%) 2(5%)

Other 2(5%) 0(0%)

*1 case died prior to identification of tuberculosis**2 case died prior to identification of tuberculosis Results may not equal 100% due to rounding

Page 19: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Who do Boston TB cases identify as their primary care site?

2011N=44

2012N=41

Hospital outpatient clinic 17 (39%) 17 (41%)

Community health center 13 (30%) 16 (39%)

Private practices 1 (2%) 1 (2%)

Other sites 6 (14%) 1 (2%)

None identified 7 (16%) 6 (15%)

Results may not equal 100% due to rounding

Page 20: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Boston Residents with Latent TB Infection (N=1,446) Evaluated at the BPHC TB Clinic, Incidence by Gender: 2012

0 25 50 75 100 125 150 175 200 225 250 275

Male

Female

Rate per 100,000

Page 21: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Boston Residents with Latent TB Infection (N=1,446) Evaluated at the BPHC TB Clinic, Incidence by Age Group: 2012

0.0

50.0

100.0

150.0

200.0

250.0

300.0

350.0

400.0

Rate per 100

,000

<10 Years 10‐19 years 20‐29 years 30‐39 years

40‐49 years 50‐59 years 60‐69 years >= 70 years

Page 22: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Percent of Boston Residents with Latent TB Infection (N=1,446) Evaluated at the BPHC TB Clinic by Race/Ethnicity: 2012

26%

39%

19%

9%3% 4%

AsianBlackHispanicOtherUnknownWhite

Page 23: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

Boston Residents with Latent TB Infection (N=1,446) Evaluated at the BPHC TB Clinic, Incidence by Neighborhood: 2012

0

100

200

300

400

500

600

Rate per 100,000

Page 24: Tuberculosis Impact in Boston Residents: 2012 · BOSTON PUBLIC HEALTH COMMISSION COMMUNICABLE DISEASE CONTROL DIVISION Sputum Smear and Culture Results for Cases with Primary Pulmonary

Building a Healthy Boston

BOSTON PUBLIC HEALTH COMMISSION ▪ COMMUNICABLE DISEASE CONTROL DIVISION

For More Information:

BOSTON PUBLIC HEALTH COMMISSIONCommunicable Disease Control Division

1010 Massachusetts AvenueBoston, MA 02118

Phone: 617‐534‐5611Fax: 617‐534‐5905

Website: www.bphc.org