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Hasanul Arifin
BAGIAN ANESTESIOLOGI DAN REANIMASIFAKULTAS KEDOKTERAN USU
MEDAN
Enteral Nutrition
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ENTERAL NUTRITION
SUPPORTI.Prerequisites
a functioning gastrointestinal tract
at least 100 cm of small bowel
condition of bowel adequate for absorption
patient incapable of adequate oral intake
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II. Advantagesless potential risk of infection, metabolic complication favours intestinal integrity and function maintains GI tract functions [ IgA, hormones, GALT ]
promotes gut motility reduces bacterial translocation from the gut less expensive product, delivery, monitoring
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III. Indications
evidence based indications existing malnutrition or risk of malnutrition
poor appetite or anorexia
prolonged fasting [>7 days]
supplementation of insufficient oral intake
for > 7 days
pragmatic indications severely stressed patients expected to be unable
to eat for 5-7 days or more severe trauma , burn
[following] small bowel resection
resumption of GI activity & preparation for oral
feeding
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IV. Contra Indication Obstruction of GI tract
Protracted vomiting or diarrhea
High output fistulas [> 500 ml] Diffuse peritonitis or ileus
Acute bowel ischemia / gut necrosis
Severe acute pancreatitis Severe short bowel syndrome [
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EVALUATE ENERGY + PROTEIN NEED
FUNCTIONAL GI-TRACT ?
NO CONTRAINDICATIONS TO EN ?
YES NOHighly catabolic state
(major trauma, burn surgery,septic shock)?
YES NO
Start PN Are conditions tostart EN present?
YES NO
Start continuous EN at500 ml/24h
Start PN andreassess daily
for conditions to
start EN
Gastric residual volume
>200ml
Reduce infusion rate by 50%4-6h, then progressiveincrease over 24-48 h
Monitor gastric residual volume 2/dayMonitor gastricresidual volume
Administer prokinetics(cisapride,metoclopramide, erythromycin)
Jolliet.P et al,Enteral nutrition in intensive care patients : a practical approach. Intensive Care Med 1998;24(8):848-859
Increase flowrate by 250-500 ml/day
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EN, administered by
Nasoenteric route
Percutaneous route
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Nasoenteric route Nasogastric, Nasoduodenal, Nasojejunal 2 -
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Nasoenteric Feeding Tube CompositionPVC Silicone PUR
Ease to insertion To stiff for comfort To soft Adequate
Ability to aspirate
gastric content
Excellent Poor to fair Good
Patient comfort Very poor Excellent Good
Durability/strength Strong but brittle Breaks easily Excellent/strong
Peggi Guenter: Delivery System Administration of Enteral Nutrition, inRombeau JL, Clinical Nutrition, Enteral and Tube Feeding,1997:244.
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Naso Gastric Tube
(NGT)
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Percutaneous route PEG, PEJ, combined nasogastric jejunal PEG, procedure of choice for ICU patients. [
4-6 weeks]
9-24Fr Relative CI, ascites, gastric cancer, gastric
ulcer, previous laparotomy, coagulation
disorder.
Post-pyloric feeding PEJ.
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PEG
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Classification of Tube Feeding Formulas
Polysaccharida, maltodextrin [60-70%NPC]
MCT, LCT [30-40% NPC]
Whole protein, partially hydrolyzed [35-40g/L formula] Isotonic [1.0-1.5 k.cal/ml]
standardised, iso osmotic (approximately 300 mOsm/L)
R/Panenteral, Nutren,
fiber enriched . R/Nutren Fibre
polymeric specialized for patients Diabetes, R/Nutren
Diabetes
Polymeric
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Elemental Chemically defined
Glucose, oligosaccharides
Crystalline amino-acids, peptide replace protein
Medium Chain Triglyceride
Specialized enteral formula [hepatic failure, renalfailure, stress-hypercatabolic ] BCAA, Glutamine
R/Peptivariant-2000
R/Peptamen
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Immune enhanced
Arginine, Glutamine, Ornithine -ketoglutarate
[OKG]
RNA
Omega-3-fatty acids
Nucleotide
R/NEOMUNE
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AlitraQ Impact Perative Stresson
units
Energy kcal/L 1000 1010 1300 1250
Protein g/L 52.5 56 66.6 75
Free-Gln g/L 15.5 0 12.2 13
Arginine g/L 4.5 12.8 8.1 9
Nucleotide g/L 0 1.3 0 0
Lipids Safflower oil Palm oil Canola oil Vegetable oil
MCT Safflower oil Corn oil Fish oil
Menhaden oil MCT Vegetable, fish
Omega-3-FA g/L 0.02 3.3 1.24 1.1
Antioxidants yes yes yes yes
Manufactured products Immune Enhanced
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Intermittent (bolus)
Administering tube feeding
naso gastric tube, gastrostomy
head up position 300
start gastric feeding of 150-200ml over 20-40 minutes,
increase by 50-100ml each feeding as tolerated to goal
followed by 30 ml warm water flush
check residuals before next feeding (up to half)
for sign of intolerance (diarrhea, vomiting), reduce to lasttolerated step, evaluate clinically.
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Continuous (drip infusion) Intragastric, duodenal, jejunal Start at 30-50 ml/hr isotonic formula
Increase by 30-50/hr every 6-8 hours to goal
Maximum 100-150ml/hr
Most tube fedings are tolerated at full strength Reduce risk ( retention, aspiration)
followed by 30 ml warm water flush
for sign of intolerance (diarrhea, vomiting),reduce to last tolerated step, evaluate clinically.
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Continuousdripinfusion
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EN + PEN
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Monitoring, Metabolic, gastrointestinal, mechanical assessment
Routine dayli evaluation of intake,output, weight
Acutely ill patients require daily to weekly serum
electrolyte, glucose, BUN, Cr, Ca++, Mg++, Ph. Stable patients require weekly-monthly laboratory
studies
Elevate head of bed 300 during feeding
Check stomach for high residuals to minimizeaspiration risk
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Metabolic : overhydration, dehydration,undernutrition, hyperglycemia,electrolyte imbalance
Gastrointestinal : nausea, vomiting, constipationabd. discomfort, diarrhea
Mechanical : misplaced, clogged feeding tubeairway, GI tract injury with NG/NJ
tube placement. Infectious : peritonitis, exit site infection, sinusitis,
aspiration pneumonia
Complications,
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