General

1Mechanics of the Unusual Basilar Membrane in GerbilSantosh Kapuria, IIT DelhiCharles Steele, Stanford Sunil Puria, Stanford

2Microstructure of BMDetailed anatomyGuinea pig: S Iurato (1962)Cat: LM Cabazudo (1978)Gerbil: Schweitzer L, Lutz C, Hobbs M, Weaver SP (1996)Point load measurementsHuman: Bksy (1960)Guinea pig: Gummer WA, Johnstone BM, Armstrong NJ (1981) Miller, C (1985)Gerbil: Olson EE, Mountain DC (1994) Naidu, RC, Mountain DC (1998) Emadi G, Richter CP, Dallos P (2004)

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Iurato 1962,gp4I- Beam

Beam with constraints5

6Gerbil organ of CortiArc of BMEdge, et al. (1998)

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Gerbil OC (Corrales, 2006)78Beam model for BM

9Arch model

10Buckling of arch

Olson and Mountain 1994 11

Emadi et al. 200412

13Emadi, et al. (2004)

Point load on arch14

15Pressure loading without Pillar stiffness

16Frequency map

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18Fast4 model of OC

Gerbil 2.75 mm, 1 kHz, wavelength = 10 mm19

Gerbil 2.75, with pressure amplitudes20

Gerbil at 2.75 mm, add axial flow amplitudes21

Gerbil at 2.75 mm, add axial flow amplitudes with viscosity22

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Gerbil at BF, add axial viscosity24AcknowledgementFulbright Fellowship to SKNIH RO1 DC00791025Close up, showing cilia and tip links

2607/07/2011Lubrication theoryHSTMIHC tip of ciliumgapTMgapHSqHSqTMpressL1pressISFluid displacement FDFDgapHSgapTM= pressL1 pressISqHSqTMperm*d/dtEdge, et al. (1998)