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KAMRAN GHAEDI, PH.D.
CURRICULUM VITAE
JANUARY, 2018
NATIONALITY: Iranian
BIRTH PLACE: Isfahan, Iran
INSTITUTE ADDRESS: Department of Cellular Biotechnology
Royan Institute for Biotechnology
Royan Institute, Academic Center for Education and Culture Research
Royan Avenue
Khorasgan, Isfahan, Iran
Phone: +98-31-9501-5694
E. mail addresses: [email protected]
[email protected] & [email protected]
HOME ADDRESS: No.76, Bahar Impasse, Asyab L
East Nazar Avenue
Isfahan, Iran
Phone: +98-31-3624-2204, Cellular Phone: +98-09133294917
PROFESSIONAL POSITIONS:
2016 – present Full Professor of Biology
Department of Biology
The University of Isfahan
Isfahan, Iran
2006 – present Principal Investigator and Head of Genetics Laboratory
Royan Institute for Biotechnology
Isfahan, Iran
2012 – 2016 Associate Professor of Biology
Department of Biology
The University of Isfahan
Isfahan, Iran
2005 – 2012 Assistant Professor of Biology
Department of Biology
The University of Isfahan
Isfahan, Iran
1993 – 1995 Lecturer of Biochemistry
Department of Biochemistry
Kashan University of Medical Sciences
Kashan, Iran
TRAINING:
2003 – 2005 Postdoctoral Researcher
(Japan Science and Technology Corporation,
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Solution-Oriented Research for Science and Technology Program)
Department of Biology, Faculty of Sciences, Kyushu University,
Fukuoka, Japan
Program Title: Expression of Organelle Biogenesis Genes and Cell-
Function Regulation
Research Director: Professor Yukio Fujiki
2001 – 2003 Postdoctoral Fellow
(Japan Society for Promotion of Science Postdoctoral Fellowship for
Foreign Researchers)
Department of Biology, Faculty of Sciences, Kyushu University,
Fukuoka, Japan
Host Researcher: Professor Yukio Fujiki
1999 – 2001 Postdoctoral Researcher
(Japan Science and Technology Corporation,
Core Research for Evolutional Science and Technology Program)
Department of Biology, Faculty of Sciences, Kyushu University,
Fukuoka, Japan
Program Title: Dynamics of Organelle Assembly and Regulation of
Cell Function
Research Director: Professor Yukio Fujiki
EDUCATION:
September, 1989 Bachelor of Science
Biology
Faculty of Sciences, The University of Isfahan
Isfahan, Iran
July, 1992 Master of Science
Clinical Biochemistry
Department of Biochemistry
Faculty of Pharmacy and Pharmaceutical Sciences
Isfahan University of Medical Sciences
Isfahan, Iran
Thesis title: Effects of thyroid hormones on the hepatic DT-diaphorase
activity and glutathione content of liver cells by in vitro and in vivo
experiments.
Supervisor: Professor Mohammad Suzangar
Advisor: Dr. Bahram Haghighi
(First rank among of graduates)
September, 1995 Japanese Language Intensive Course Certificate
International Student Center
Kyushu University
Fukuoka, Japan
March, 1996 Non-degree Research Student
Department of Biology
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Graduate School of Sciences, Kyushu University
Fukuoka, Japan
March, 1999 Doctor of Science
Department of Biology
Graduate School of Sciences, Kyushu University
Fukuoka, Japan
Dissertation title: Isolation and characterization of two novel-
complementation groups of Chinese hamster ovary cell mutants
defective in peroxisome assembly and their complementing genes,
using green fluorescent protein tagged with peroxisomal targeting
signal type 2 (PTS2).
Supervisor: Professor Yukio Fujiki
HONORS:
The Winner of the Biennial Book Festival in Isfahan province for writing of Stem Cells
and Tissue Regeneration book in Persian (DECEMBER, 2016) by Department of Culture and
Islamic Guidance of Isfahan Province
National Winner of the “Royan 17th International Research Award”. in the field of
Stem Cell Biology and Technology. AUGUST, 2016 by Royan Institute
Title of research: “Utilization of Pioglitazone as a Novel Approach to Increase the Colony
Formation Efficiency of Individualized Human Pluripotent Stem Cells”.
Distinguished National Investigator for the Fiscal Year of 2015 by Ministry of Research,
Science and Technology of Iran
Distinguished University Investigator for the Fiscal Year of 2014 by University of Isfahan
Distinguished Biology Department Investigator for the Fiscal Year of 2011 by University
of Isfahan
The tenth award seasonal book for best translation (SEPTEMBER, 2010) by Ministry of
Culture and Islamic Guidance.
TEACHING RESPONSIBILITIES (UNIVERSITY OF ISFAHAN):
Yearly: Seminars
PhD. Seminar
MSc. Seminar
Lectures- Graduate Courses
Advanced Molecular Biology
Advanced Cell Biology 2
Molecular Biology of Genome
Cellular Adaptation to Exercise
Metabolic Aspects of Exercise
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Hormone Responses to Exercise
Advanced Genetic Engineering
Complementary Genetic Engineering
Experimental Methods of Biochemistry and Exercise Metabolism
Biennial: Lectures- Graduate Courses
Developmental Genetics
Advanced Cell Biology
Developmental Genetics
Advanced Cell Biology 1
Occasional: Lectures- Graduate Courses
Recent Progress in Genetics
Regulation of Metabolism
Advanced Techniques in Cell and Molecular Biology
Cell Physiology
Membrane Biology and Physiology
Chromatin Biochemistry
Stem Cells
Lectures- Undergraduate Courses
Complementary Biochemistry
Special Topics in Genetics
Genetic Engineering
Foundation of Genetics
Biochemistry of Metabolism
Genetics I
Biochemistry of Proteins
Once: Lectures- Graduate Courses
Medical Biochemistry
Advanced Sport Biochemistry
Molecular Biotechnology
Bacterial Genetics
Lectures- Undergraduate Courses
Animal Biotechnology
Basic Biotechnology
Foundation of Biochemistry
Immunogenetics
UNIVERSITY COMMITTEE MEMBERSHIPS AND ACTIVITIES:
2005 – 2007 Member of Book Committee, Biology Department
2005– 2009 Biology Department Coordinator for Graduate Seminars
2005 – 2007 Biology Department Coordinator for Launching Master
Program of Cell and Molecular Biology
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2007 – 2009 Member of Research Affairs Committee, Biology Department
2008 – 2010 Member of Book Committee, Faculty of Sciences
2007 – 2013 Member of Academic Selection Committee for hiring new faculty
staffs, University of Isfahan
2009 – 2011 Member of Graduate Administration Committee, Biology Department
2009 – 2013 Member of Administration Policy Committee, Biology Department
2009 – Present Secretary of Stem Cell Committee, University of Isfahan
2013 – Present Member of Biotechnology Committee, University of Isfahan
2009 – Present Member of Administration Policy Committee, University of Isfahan
2011 – 2013 Member of Academic Committee, Biology Department
2011 – Present Member of Academic Committee, Biotechnology Department
2012 – 2013 Biology Department Coordinator for Launching Ph.D.
Program of Cell and Molecular Biology
2012 – 2013 Biology Department Coordinator for Launching Ph.D.
Program of Cell and Developmental Biology
PUBLISHED PAPERS:
Sekhavati MH, Hosseini SM, Tahmoorespur M, Ghaedi K, Jafarpour F, Hajian M,
Dormiani K, Nasr-Esfahani MH. (2018) PhiC31-based Site-Specific Transgenesis System for
Production of Transgenic Bovine Embryos by Somatic Cell Nuclear Transfer and Intracytoplasmic
Sperm Injection. Cell J (Yakhteh) 20(1):98-107.
Hashemi MS, Mozdarani H, Ghaedi K, Nasr-Esfahani MH. (2018) Expression of
ZMYND15 in Testes of Azoospermic Men and Association with Sperm Retrieval. Urology. In press
Nazem S, Rabiee F, Ghaedi K, Babashah S, Sadeghizadeh M, Nasr-Esfahani MH. (2018)
Fndc5 Knockdown Induced Suppression of Mitochondrial Integrity And Significantly Decreased
Cardiac Differentiation of Mouse Embryonic Stem Cells. J Cell Biochem. In press
Mazaheri N, Peymani M, Galehdari H, Ghaedi K, Ghoochani A, Kiani-Esfahani A, Nasr-
Esfahani MH. (2018) Ameliorating Effect of Osteopontin on H2O2-Induced Apoptosis of Human
Oligodendrocyte Progenitor Cells. Cell Mol Neurobiol. In press.
Safaeinejad, Z., Nabiuni, M., Peymani, M., Ghaedi, K., Nasr-Esfahani, M.H., Baharvand H.
(2017) Resveratrol promotes human embryonic stem cells self-renewal by targeting SIRT1-ERK
signaling pathway. Eur J Cell Biol (17):30178-4.
Rouigari, M., Dehbashi, M., Ghaedi, K., Pourhossein, M. (2017) Targetome analysis
revealed involvement of miR-126 in neurotrophin signaling pathway: A possible role in prevention
of glioma progress. Cell J (Yakhteh) (In press).
Kashfi, S., Peymani, M., Ghaedi, K., Baharvand, H., Nasr-Esfahani, M.H., Javan, M.
(2017) Purinergic receptor expression and potential association with human embryonic stem cell
derived oligodendrocyte progenitor cell development. Cell J (Yakhteh) 9(3):386-402.
Peymani, M., Ghaedi, K., Hashemi, M.S., Ghoochani, A., Kiani-Esfahani, A., Nasr-
Esfahani, M.H., Baharvand, H. (2017) Ameliorating the effect of Pioglitazone on LPS-induced
inflammation of human oligodendrocyte progenitor cells. Cell Mol Neurobiol (In Press).
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Yarjanli, Z., Ghaedi, K., Esmaeili, A., Rahgozar, S., Zarrabi A.(2017) Iron oxide
nanoparticles may damage to the neural tissue through iron accumulation, oxidative stress, and
protein aggregation. BMC Neurosci 18(1):51.
Jodeiri Farshbaf, M., Ghaedi, K. (2017) Huntington's disease and mitochondria. Neurotox
Res (In Press)
Esmaeili, A., Pakravan, G., Ghaedi, K., Noorbakhshnia, M. (2017) Alteration in messenger
RNA neurotrophin 4 and tyrosine kinase receptors B expression levels following spinal cord injury.
Journal of Neurosurgical Sciences (In Press).
Kashfi, S., Ghaedi, K., Baharvand, H., Nasr-Esfahani, M.H., Javan, M. (2017) A1
Adenosine Receptor Activation Modulates Central Nervous System Development and Repair. Mol
Neurobiol (In Press).
Fatemi, M., Moshtaghian, J., Ghaedi, K., Jafari dinani, N., Naderi, G. (2017) Effects of
silver nanoparticle on the developing liver of rat pups after maternal exposure. Iranian Journal of
Pharmaceutical Research16 (2): 685-693
Kazeminasab, F., Marandi, M., Ghaedi, K., Esfarjani, F., Moshtaghian, J. (2017) Effects of
a 4-week aerobic exercise on lipid profile and expression of LXRα in rat liver. Cell J (Yakhteh)
19(1):45-49.
Dehghan, Z., Sadeghi, S., Tabatabaeian, H., Ghaedi, K., Azadeh, M., Fazilati, M., Bagheri,
F. (2017) ESR1 single nucleotide polymorphism rs1062577 (c.*3804T>A) alters the susceptibility
of breast cancer risk in Iranian population. Gene 611:9-14.
Tavalaee, M., Parivar, K., Shahverdi, A.H., Ghaedi, K., Nasr-Esfahani, M.H. (2017) Status
of sperm-born oocyte activating factors (PAWP, PLCζ) and sperm chromatin in uncapacitated,
capacitated and acrosome-reacted conditions. Hum Fertil (Camb) 20(2):96-103.
Dormiani, K., Mir Mohammad Sadeghi, H., Sadeghi-Aliabadi, H., Forouzanfar, M.,
Baharvand, H., Ghaedi, K., Nasr-Esfahani, M.H. (2017) Rational development of a polycistronic
plasmid with a CpG-free bacterial backbone as a potential tool for direct reprogramming. Cell J
(Yakhteh) 18(4):565-581.
Batavani, M.R., Marandi, S.M., Ghaedi, K., Esfarjani, F. (2017) Frequency analysis of
rs4646994 polymorphism in angiotensin converting enzyme (ACE) gene in professional karateka
athletes compared to the amateur athletes and non-athlete individuals. Journal of Isfahan Medical
School 34 (406):1323-1329. (Persian)
Jenab, A., Roghanian, R., Emtiazi G., Ghaedi, K. (2017) Manufacturing and structural
analysis of antimicrobial kefiran/polyethylene oxide nanofibers for food packaging. Iranian
Polymer Journal 26 (1): 31-39.
Moradi, B., Tabatabaeian, H., Sadeghi, S., M Azadeh, Ghaedi, K. (2016) HER4 rs1595065
3'UTR variant is a possible risk factor for HER2 positivity among breast cancer patients. Thrita 5 (4):
e42195
Tavalaee, M., Parivar, K., NasrEsfahani, M.H., Shahverdi, A., Ghaedi, K. (2016)
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Comparison of sperm chromatin structure and PLCζ between infertile
oligoasthenoteratozoospermic and fertile men. J Shahrekord Univ Med Sci 18(4): 9-
19. (Persian).
Reisi, J., Ghaedi, K., Rajabi, H., Marandi, S.M. (2016) Can resistance exercise alter irisin
levels and expression profiles of FNDC5 and UCP1 in rats? Asian J Sports Med 7(4):e35205.
Jodeiri Farshbaf, M., Ghaedi, K. (2016) Does any drug to treat cancer target mTOR and iron
hemostasis in neurodegenerative disorders? Biometals 30(1):1-16.
Zabihi, N., Sadeghi, S., Tabatabaeian, H., Ghaedi, K., Azadeh, M.,Fazilati, M. (2017) The
association between rs1972820 and the risk of breast cancer in Isfahan population. J Cancer Res
Ther 13(1):26-32.
Kabirizadeh,S., Azadeh M, Mirhosseini M., Ghaedi, K., Mesrian Tanha, H. (2016) The
SNP rs3746444 within mir-499a is associated with breast cancer risk in Iranian population. Journal
of Cellular Immunotherapy 2:95-97.
Noormohammad, M., Sadeghi, S., Tabatabaeian, H., Ghaedi, K., Talebi, A., Azadeh, M.,
Khatami, M., Heidari, M.M. (2016) Upregulation of miR-222 in both Helicobacter pylori-infected
and noninfected gastric cancer patients. Journal of Genetics 95(4):991-995.
Javadirad, S.M., Hojati, Z., Ghaedi, K., Nasr-Esfahani, M.H., Abbasy, Behzad. (2016)
Evaluation of the Most Stable Reference Genes in Testicular Tissue of the Men with Azoospermia.
J Isfahan Med School 33(367): 2407-16.
Hasanzadeh, A., Tanha, H.M., Ghaedi, K., Madani, M. (2016) Aberrant expression of miR-
9 in benign and malignant breast tumors. Mol Cell Probes 30(5):279-284.
Hosseini, A., Ghaedi, K., Tanhaei, S., Ganjalikhani-Hakemi, M., Teimuri, S., Etemadifar,
M., Nasr Esfahani, M.H. (2016) Upregulation of CD4+T-cell derived MiR-223 in the relapsing
phase of multiple sclerosis patients. Cell J (Yakhteh) 18(3):371-80.
Peymani, M., Ghaedi, K., Irani, S., Nasr-Esfahani, M.H. (2016) Peroxisome proliferator-
activated receptor γ activity is required for appropriate cardiomyocyte differentiation. Cell J
(Yakhteh) 18(2):221-8.
Kiani-Esfahani, A., Kazemi Sheykhshabani, S., Peymani, M., Hashemi, M.S., Ghaedi, K.,
Nasr-Esfahani, M.H. (2016) Overexpression of Annexin A1 suppresses pro-inflammatory factors in
PC12 cells induced by 1-methyl-4-phenylpyridinium. Cell J (Yakhteh) 18(2):197-204.
Modarres, P., Tanhaei, S., Tavalaee, M., Ghaedi, K., Deemeh, M.R., Nasr-Esfahani,
M.H.(2016) Assessment of DPY19L2 deletion in familial and non-familial individuals with
globozoospermia and DPY19L2 genotyping. Int J Fertil Steril 10(2):196-207
Jodeiri Farshbaf, M., Forouzanfar, M., Ghaedi, K., Kiani-Esfahani, A., Peymani, M.,
Shoaraye Nejati, A., Izadi, T., Karbalaie, K., Noorbakhshnia, M., Rahgozar, S., Baharvand, H.,
Nasr-Esfahani, M.H. (2016) Nurr1 and PPARγ protect PC12 cells against MPP(+) toxicity:
involvement of selective genes, anti-inflammatory, ROS generation, and antimitochondrial
impairment. Mol Cell Biochem 420(1-2):29-42.
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Meshkat, M., Tanha, H.M., Naeini, M.M., Ghaedi, K., Sanati, M.H., Meshkat, M., Bagheri,
F. (2016) Functional SNP in stem of mir-146a affects Her2 status and breast cancer survival. Cancer
Biomark 17(2):213-22.
Salimi, Z., Sadeghi, S., Tabatabaeian, H., Ghaedi, K., Fazilati, M. (2016) rs11895168 C
allele and the increased risk of breast cancer in Isfahan population. Breast 28:89-94.
Mehrasa, M., Asadollahi, M.A., Nasri-Nasrabadi, B., Ghaedi, K., Salehi, H., Dolatshahi-
Pirouz, A., Arpanaei, A. (2016) Incorporation of mesoporous silica nanoparticles into random
electrospun PLGA and PLGA/gelatin nanofibrous scaffolds enhances mechanical and cell
proliferation properties. Mater Sci Eng C Mater Biol Appl 66:25-32.
Javadian-Elyaderani, S., Ghaedi, K., Tavalaee, M., Rabiee, F., Deemeh, M.R., and Nasr-
Esfahani, M.H. (2016) Diagnosis of genetic defects through parallel assessment of PLCζ and
CAPZA3 in infertile men with history of failed oocyte activation. Iran J Basic Med Sci 19(3):281-9.
Bagheri, F., Mesrian Tanha, H., Mojtabavi Naeini, M., Ghaedi, K., and Azadeh, M. (2016)
Tumor-promoting function of single nucleotide polymorphism rs1836724 (C3388T) alters multiple
potential legitimate microRNA binding sites at the 3'-untranslated region of ErbB4 in breast cancer.
Mol Med Rep 13(5):4494-8.
Javadirad ,S.M., Hojati, Z., Ghaedi, K., and Nasr-Esfahani, M.H. (2016) Expression ratio of
histone demethylase KDM3A to protamine-1 mRNA is predictive of successful testicular sperm
extraction in men with obstructive and non-obstructive azoospermia. Andrology 4(3):492-9.
Hashemi, M.S., Esfahani, A.K., Peymani, M., Nejati, A.S., Ghaedi, K., Nasr-Esfahani, M.H,
and Baharvand, H. (2016) Zinc finger protein 521 overexpression increased transcript levels of
Fndc5 in mouse embryonic stem cells. Journal of Biosciences 41(1), 69-76.
Jodeiri Farshbaf, M., Ghaedi, K., Megraw, T.L., Curtiss, J., Shirani Faradonbeh, M., Vaziri,
P., and Nasr-Esfahani, M.H. (2016) Does PGC1α/FNDC5/BDNF elicit the beneficial effects of
exercise on neurodegenerative disorders? Neuromolecular Medicine 18(1), 1-15.
Aghaei S., Saffar B., Ghaedi, K., and Mobini Dehkordi, M. (2016) Functional analysis of
recombinant codon-optimized bovine neutrophil β-defensin. Journal of Advanced Research
7 (5): 815-821
Kazempour, M., Ghaedi, K., Madani, M. (2016) A mini review on modulation of MiR-155
expression in different cancer diseases. Genetics in the 3rd Millennium 13(4), 4128-4133.
Darehgazani, R., Peymani, M., Hashemi, M.S., Omrani, M.D., Movafagh, A., Ghaedi, K.,
and Nasr-Esfahani, M.H. (2016) PPARγ ameliorated LPS induced inflammation of HEK cell line
expressing both human Toll-like receptor 4 (TLR4) and MD2. Cytotechnology 68 (4):1337-1348.
Karimi, N., Saffar B., Mobini, M., and Ghaedi, K. (2016) Design, construction, cloning and
expression of beta defensing and its effect on wound healing. Koomesh 17 (2), 358-365 (Persian).
Katebi, S., Esmaeili, A., Ghaedi, K. (2016) Static magnetic field reduced exogenous
oligonucleotide uptake by spermatozoa using magnetic nanoparticle gene delivery system. Journal
of Magnetism and Magnetic Materials 402,184-189.
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Ahmadian-Elmi, M., Bidmeshki Pour, A., Naghavian, R., Ghaedi, K., Tanhaei, S., Izadi, T.,
and Nasr-Esfahani M. H. (2016) miR-27a and miR-214 exert opposite regulatory roles in Th17
differentiation via mediating different signaling pathways in peripheral blood CD4(+) T
lymphocytes of patients with relapsing-remitting multiple sclerosis. Immunogenetics 68(1), 43-54.
Esmaeili, M., Ghaedi, K., Shoaraye Nejati, A., Nematollahi, M., Shiralyian, H., and Nasr-
Esfahani, M.H. (2016) Pioglitazone significantly prevented decreased rate of neural differentiation
of mouse embryonic stem cells which was reduced by Pex11β knock-down. Neuroscience 312, 35-
47.
Nazem, S., Ghaedi, K., Babashah, S., Sadeghizadeh, M., Nasr Esfahani, M.H. (2016)
Construction of recombinant lentiviral vector containing shRNA against mouse Fndc5 gene in
order to transduce mouse embryonic stem cells. Pathobiology Research 19(2): 59-73
Adami, B., Ghaedi, K., Talebi, A. (2016) In silico studies revealed a crucial role
for miR-146a on progression of Helicobacter pylori induced gastric cancer. Sci J Iran Blood
Transfus Organ 14(1): 65-76. (Persian).
Mirzaeian, P., Esfarjani, F., Moshtaghian, J., Marandi, S.M., Ghaedi, K., Ghorbani, N.
(2016) The effects of moderate intense endurance exercise on pro-inflammatory cytokine in
balb/c mice breast cancer model. J Shahrekord Univ Med Sci 18(4):74-80. (Persian).
Eghbalsaied, S., Amini, H., Ghaedi, K., Pirestani, A., and Nabizadeh, P. (2015) In vivo
evaluation of ovine sperm/embryo ability in mediating transgenic lamb. Middle East Fertility
Society Journal 20, 295-296.
Golabgir, M., Mowla, S.J., Ghaedi, K., Nasr Esfahani, M.H. (2016) Bioinformatic study on
possible roles of miR-9, miR-17 and miR-106a/b in differentiation of TH17 cells of multiple
sclerosis. Biotechnology Journal of Tarbiat Modares University 7 (1):60-70. (Persian).
Peymanfar, S., Roghanian, R., Ghaedi, K., Zarkesh, S.H., Yari, L. (2016) Production and
simple purification of recombinant human granulocyte colony-stimulating factor using the intein tag
in Escherichia coli. International Journal of Medical Biotechnology and Genetics 5 (1):40-46.
Taheri, M., Salamian, A., Ghaedi, K., Peymani, M., Izadi, T., Nejati, A.S., Atefi, A.,
Nematollahi, M., Ahmadi Ghahrizjani, F., Esmaeili, M., Kiani Esfahani, A., Irani, S., Baharvand, H.,
and Nasr-Esfahani, M.H. (2015) A ground state of PPARγ activity and expression is required for
appropriate neural differentiation of hESCs. Pharmacological Reports 67(6), 1103-14.
Ganjuri, M., Moshtaghian, J., and Ghaedi, K. (2015) Effect of nanosilver particles on
procaspase-3 expression in newborn rat brain. Cell Journal (Yakhteh) 17(3), 489-93.
Kajabadi, N.S., Ghoochani, A, Peymani, M., Ghaedi, K., Kiani-Esfahani, A., Hashemi, M.S.,
Nasr-Esfahani, M.H., and Baharvand, H. (2015) The synergistic enhancement of cloning efficiency
in individualized human pluripotent stem cells by peroxisome proliferative-activated receptor-γ
(PPARγ) activation and rho-associated kinase (ROCK) inhibition. Journal of Biological Chemistry
290(43), 26303-13.
Dormiani, K., Mir Mohammad Sadeghi, H., Sadeghi-Aliabadi, H., Ghaedi, K., Forouzanfar,
M., Baharvand, H., and Nasr-Esfahani, M.H. Long-term and efficient expression of human β-globin
gene in a hematopoietic cell line using a new site-specific integrating non-viral system. Gene
Therapy 22(8), 663-74.
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Honardoost, M.A., Naghavian, R., Ahmadinejad. F., Hosseini, A., and Ghaedi, K. (2015)
Integrative computational mRNA-miRNA interaction analyses of the autoimmune-deregulated
miRNAs and well-known Th17 differentiation regulators: An attempt to discover new potential
miRNAs involved in Th17 differentiation. Gene 572(2), 153-62.
Mehrasa, M., Asadollahi, M.A., Ghaedi, K., Salehi, H., and Arpanaei, A. (2015)
Electrospun aligned PLGA and PLGA/gelatin nanofibers embedded with silica nanoparticles for
tissue engineering. International Journal of Biological Macromolecules 79, 687-95.
Sanei Ata-Abadi, N., Dormiani, K., Khazaie, Y., Ghaedi, K., Forouzanfar, M., Lachinani, L.,
Rezaei, N., Kiani-Esfahani, A., and Nasr-Esfahani, M.H. (2015) Construction of a new minicircle
DNA carrying an enhanced green florescent protein reporter gene for efficient expression into
mammalian cell lines. Molecular Biology Reports 42(7), 1175-85.
Hosseini Farahabadi, S.S., Ghaedi, K., Ghazvini Zadegan, F., Karbalaie, K., Rabiee, F.,
Nematollahi, M., Baharvand, H., and Nasr-Esfahani, M.H. (2015) ERK1/2 is a key regulator of
Fndc5 and PGC1α expression during neural differentiation of mESCs. Neuroscience 297, 252-61.
Zadegan, F.G., Ghaedi, K., Kalantar, S.M., Peymani, M., Hashemi, M.S., Baharvand, H.,
and Nasr-Esfahani M.H. (2015) Cardiac differentiation of mouse embryonic stem cells is influenced
by a PPAR γ/PGC-1α-FNDC5 pathway during the stage of cardiac precursor cell formation.
European Journal of Cell Biology 94(6), 257-66.
Naghavian, R., Honardoost, M.A., Hosseini, A., Ghaedi, K., Etemadifar, M., Nasr Esfahani,
M.H., Ganjalikhani Hakemi, M. (2015) The possibility of miR-20a/b & miR-93 role in
differentiation of naïve CD4+ to Th17 cells in multiple sclerosis. Scientific Journal of Iran Blood
Transfusion Organization 12(1), 39-45 (Persian).
Naghavian, R, Ghaedi, K., Kiani-Esfahani, A., Ganjalikhani-Hakemi, M., Etemadifar, M.,
and Nasr-Esfahani, M.H. (2015) miR-141 and miR-200a, revelation of new possible players in
modulation of Th17/Treg differentiation and pathogenesis of multiple sclerosis. PLoS One 10(5),
e0124555.
Forouzanfar, M., Rabiee, F., Ghaedi, K., Beheshti, S., Tanhaei, S., Shoaraye Nejati, A.,
Jodeiri Farshbaf, M., Baharvand, H., and Nasr-Esfahani, M.H. (2015) Fndc5 overexpression
facilitated neural differentiation of mouse embryonic stem cells. Cell Biology International 39(5),
629-37.
Kazemi, S., Kiani-Esfahani, A., Ghaedi, K., Sekhavati, M.H., Ajamian, F., and Nasr-
Esfahani, M.H. (2015) Construction of human Annexin A1 cDNA in a eukaryotic expression vector.
Genetics in the 3rd Millennium 13(1), 3932-3938.
Dehkordi, N.G., Noorbakhshnia, M., Ghaedi, K., Esmaeili, A., and Dabaghi, M. (2015)
Omega-3 fatty acids prevent LPS-induced passive avoidance learning and memory and CaMKII-α
gene expression impairments in hippocampus of rat. Pharmacological Reports 67(2), 370-5.
Ziaei, A., Ardakani, M.R., Hashemi, M.S., Peymani, M., Ghaedi, K., Baharvand, H., and
Nasr-Esfahani, M.H. (2015) Acute course of deferoxamine promoted neuronal differentiation of
neural progenitor cells through suppression of Wnt/β-catenin pathway: a novel efficient protocol for
neuronal differentiation. Neuroscience Letters 590, 138-44.
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Parvizian, H., Keyhanfar, M., Ghaedi, K., Etemadifar, M., and Alsahebfosoul, F. (2015)
Cloning and expression of brain-derived neurotrophic factor (BDNF) in Escherichia coli. Genetics
in the 3rd Millennium 12(4), 3762-3768. (Persian).
Ghahrizjani, F.A., Ghaedi, K., Salamian, A., Tanhaei, S., Nejati, A.S., Salehi, H., Nabiuni,
M., Baharvand, H., and Nasr-Esfahani, M.H. Enhanced expression of FNDC5 in human embryonic
stem cell-derived neural cells along with relevant embryonic neural tissues. Gene 557(2), 123-9.
Babolmorad, G., Emtiazi, G., Ghaedi, K., Jodeiri, M. (2015) Enhanced PC12 cells
proliferation with self-assembled S-layer proteins scaffolds. Applied Biochemistry and
Biotechnology175(1), 223-31.
Ghavimi,R., Pourhossein,M., Ghaedi, K., Alesahebfosoul,F., Honardoost, M.A., and
Maracy, M.A. (2014) Genetic association of rs1520333 G/A polymorphism in the gene with
multiple sclerosis susceptibility in Isfahan population. Advanced Biomedical Research 3, 238.
Aghaabdollahian, S., Rabbani, M., Ghaedi, K., and Sadeghi, H.M. (2014) Molecular
cloning of Reteplase and its expression in E. coli using tac promoter. Advanced Biomedical
Research 3, 190.
Sekhavati , M.H., Tahmoorespur, M., Jafarpour , F., Dormiani, K., Khazaie, Y., Ghaedi, K.,
Hosseini, S.M., Forouzanfar , M., and Nasr Esfahani, M.H. (2014) Identification of a specific
pseudo attP site for phage phiC31 integrase in bovine genome. Iranian Journal of Biotechnology
12(4), e1013.
Sadeghi, M., Hojati, Z., and Ghaedi, K. (2014) Cloning and expression of VEGF111b, a
new isoform of VEGF family with antiangiogenic activity. International journal of Integrative
Biology 15(2), 31-35.
Sadeghi, M., Hojati, Z., and Ghaedi, K. (2014) Assay of relation between the vascular
endothelial growth factor expression and breast cancer tumor formation. Arak Medical University
Journal 17(89), 27-34. (Persian).
Rabiee, F., Forouzanfar, M., Ghazvini Zadegan, F., Tanhaei, S., Ghaedi, K., Motovali Bashi,
M., Baharvand, H., and Nasr-Esfahani, M.H. (2014) Induced expression of Fndc5 significantly
increased cardiomyocyte differentiation rate of mouse embryonic stem cells. Gene 551(2), 127-37.
Pourhossein, M., Ghavimi, R., Alsahebfosoul, F., Ghaedi, K. (2014) Association between
rs1800795 (-174 G/C) polymorphism in the promoter of IL6 gene and risk of relapsing-remitting
multiple sclerosis (RRMS) in Isfahan population. Open Journal of Genetics 4, 407-413.
Jamshidifar, M., Zarkesh Esfahani, S.H., and Ghaedi, K. (2014) Subcloning of the single
chain variable fragment of anti-human CD4 receptor fused to green fluorescent protein in pET26b
plasmid. Genetics in the 3rd Millennium 12(1), 3400-3409. (Persian).
Tolouei, S., Hejazi, S.H., Ghaedi, K., Hasheminia, S.J. (2014) Identification of leishmania
isolates from healing and nonhealing cutaneous leishmaniasis patients using internal transcribed
spacer region PCR. Jundishapur Journal of Microbiology 7(4), e9529.
12
Noguchi, M., Honsho, M., Abe, Y., Toyama, R., Niwa, H., Sato, Y., Ghaedi, K.,
Rahmanifar, A., Shafeghati, Y., and Fujiki, Y. (2014) Mild reduction of plasmalogens causes
rhizomelic chondrodysplasia punctata: functional characterization of a novel mutation. Journal of
Human Genetics 59(7):387-92.
Farahabadi, S.S., Karbalaie, K., Salehi, H., Rabiee, F., Ghaedi, K., and Nasr-Esfahani, M.H.
(2014) An in vitro study on chick somite ability to express cerberus, chordin, FGF8, follistatin, and
noggin transcripts. Avicenna Journal of Medical Biotechnology 6(2), 119-22.
Honardoost, M.A., Kiani-Esfahani, A., Ghaedi, K., Etemadifar, M., and Salehi, M. (2014)
miR-326 and miR-26a, two potential markers for diagnosis of relapse and remission phases in
patient with relapsing-remitting multiple sclerosis. Gene 544(2), 128-33.
Seifi, T., Ghaedi, K., Tanhaei, S., Karamali, F., Kiani-Esfahani, A., Peymani, M.,
Baharvand, H., and Nasr-Esfahani, M.H. (2014) Identification, cloning, and functional analysis of
the TATA-less mouse FNDC5 promoter during neural differentiation. Cellular and Molecular
Neurobiology 34(5), 715-25.
Ganjalikhani Hakemi, M., Ghaedi, K., Homayouni, V., Andalib, A., Hosseini, M., and
Rezaei, A.(2014) Positive and negative regulation of Th17 cell differentiation: evaluating the impact
of RORC2. Cell Journal (Yakheth) 16(3), 343-52.
Farshbaf, M.J., Ghaedi, K., Shirani, M., Nasr-Esfahani, M.H. (2014) Peroxisome
proliferator activated receptor gamma (PPARγ) as a therapeutic target for improvement of cognitive
performance in Fragile-X. Medical Hypotheses 82(3), 291-4.
Tousheh, M., Miroliaei, M., Rastegari, A., Ghaedi, K., Esmaeili, A., and Matkowski, A.
(2014) Computational evaluation on the binding affinity of non-specific lipid-transfer protein-2 with
fatty acids. Computers in Biology and Medicine 43(11), 1732-8.
Rahgozar, S., Moafi, A., Abedi, M., Entezar-E-Ghaem, M., Moshtaghian, J., Ghaedi, K.,
Esmaeili, A., and Montazeri, F. (2014) mRNA expression profile of multidrug-resistant genes in
acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2. Cancer
Biology and Therapy 15(1), 35-41.
Tolouei, S., Hejazi, S.H., Ghaedi, K., Khamesipour, A., and Hasheminia, S.J. (2013) TLR2
and TLR4 in cutaneous leishmaniasis caused by Leishmania major. Scandinavian Journal of
Immunology 78(5), 478-84.
Kazeminasab, F., Marandi, M., Ghaedi, K., Esfarjani, F., and Moshtaghian, J. (2013)
Endurance training enhances LXRα gene expression in Wistar male rats. European Journal
of Applied Physiology 113(9), 2285-90.
Peymani, M., Ghoochani, A., Ghaedi, K., Karamali, F., Karbalaie, K., Kiani-Esfahani, A,
Rabiee, F., Nasr-Esfahani, M.H., and Baharvand, H. (2013) Dual effects of peroxisome
proliferator-activated receptor γ on embryonic stem cell self-renewal in presence and absence of
leukemia inhibitory factor. European Journal of Cell Biology 92(4-5), 160-8.
Ganjalikhani Hakemi, M., Ghaedi, K., Andalib, A., Homayouni, V., Hosseini, M., and
Rezaei, A. (2013) RORC2 gene silencing in human Th17 cells by siRNA: design and evaluation of
highly efficient siRNA. Avicenna Journal of Medical Biotechnology 5(1), 10-19.
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Ghorbani, R., Emamzadeh, A., Khazaie, Y., Dormiani, K., Ghaedi, K., Rabbani, M.,
Foruzanfar, M., Karbalaie, K., Karamali, F., Lachinani, L., Kiani-Esfahani, A., Nematollahi, M.,
and Nasr Esfahani, M.H. (2014) Constructing a mouse Oct4 promoter/EGFP vector, as a whole
cellular reporter to monitor the pluripotent state of cells. Avicenna Journal of Medical
Biotechnology 5(1), 2-9.
Sekhavati, M.H., Tahmoorespur, M., Ghaedi, K., Dormiani, K., Nassiri, M.R., Khazaie, Y.,
Foruzanfar, M., Hosseini, M., and Nasr Esfahani, M.H. (2013) Cloning, expression, and in vitro
functional activity assay of phiC31 integrase cDNA in Escherichia coli. Cell Journal (Yakheth)
14(4), 264-9.
Salamian, A., Mohamadynejad, P., Ghaedi, K., Nejati, A.S., Shafeghati, Y., Ahnak, M.B.,
Nematollahi, M., Karbalaie, K., Hadipour, F., Baharvand, H., and Nasr-Esfahani, M.H. (2013)
C86Y: as a destructive homozygous mutation deteriorating Pex7p function causing rhizomelic
chondrodysplasia punctata type I. Annals of Clinical Laboratory Sciences 43(1), 76-80.
Mohammadi, E., Ghaedi, K., Esmailie, A., and Rahgozar, S. (2013) Gene expression
profiling of liver X receptor α and Bcl-2-associated X protein in experimental transection spinal
cord-injured rats. Journal of Spinal Cord Medicine 36(1), 66-71.
Mohamadynejad, P., Ghaedi, K., Shafeghati, Y., Salamian, A., Tanhaie, S., Karamali, F.,
Rabiee, F., Parivar, K., Baharvand, H ., and Nasr-Esfahani, M.H. (2013) Identification of a novel
missense mutation of PEX7 gene in an Iranian patient with rhizomelic chondrodysplasia punctata
type 1. Gene 518(2), 461-6.
Hashemi, M.S., Ghaedi, K., Salamian, A., Karbalaie, K., Emadi-Baygi, M., Tanhaei, S.,
Nasr-Esfahani, M.H., and Baharvand, H. (2013) Fndc5 knockdown significantly decreased neural
differentiation rate of mouse embryonic stem cells. Neuroscience 231, 296-304.
Eghbalsaied, S., Ghaedi, K., Laible, G., Hosseini, S.M., Forouzanfar, M., Hajian, M., Oback,
F., Nasr-Esfahani, M.H., and Oback, B. (2013) Exposure to DNA is insufficient for in vitro
transgenesis of live bovine sperm and embryos. Reproduction145(1), 97-108.
Ghazvini Zadegan, F., Kalantar, S.M., Ghaedi, K., Hashemi, M.S., and Nasr Esfahani,
M.H. (2013) Analysis of PEP expression pattern during cardiogenesis of mouse embryonic stem
cells. Genetics in the 3rd Millennium 10(4), 2900-2905. (Persian).
Tolouei, S., Ghaedi, K., Khamesipour, A., Akbari, M., Baghaei, M., Hasheminia, S.,
Narimani, M., and Hejazi, S. (2012) IL-23 and IL-27 Levels in Macrophages Collected from
Peripheral Blood of Patients with Healing Vs Non-Healing Form of Cutaneous Leishmaniasis.
Iranian Journal of Parasitology 7(1), 18-25.
Elinati, E., Kuentz, P., Redin, C., Jaber, S., Vanden Meerschaut, F., Makarian, J., Koscinski,
I., Nasr-Esfahani, M.H., Demirol, A., Gurgan, T., Louanjli, N., Iqbal, N., Bisharah, M., Pigeon, F.C.,
Gourabi, H., De Briel, D., Brugnon, F., Gitlin, S.A., Grillo, J.M., Ghaedi, K., Deemeh, M.R.,
Tanhaei, S., Modarres, P., Heindryckx, B, Benkhalifa, M., Nikiforaki, D., Oehninger, S.C., De
Sutter, P., Muller, J., and Viville, S. (2012) Globozoospermia is mainly due to DPY19L2 deletion
via non-allelic homologous recombination involving two recombination hotspots. Human Molecular
Genetics 21(16), 3695-702.
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Eghbalsaied, S., Ghaedi, K., Shahmoradi, S., Pirestani, A., Amini, H., Saiedi, T., Nicol, L.,
and McNeilly, A. (2012) Presence of SNPs in GDF9 mRNA of Iranian Afshari sheep. International
Journal of Fertility and Sterility 5(4), 225-30.
Ghoochani, A., Shabani, K., Peymani, M., Ghaedi, K., Karamali, F., Karbalaei, K., Tanhaie,
S., Salamian, A., Esmaeili, A., Valian-Borujeni, S., Hashemi, M., Nasr-Esfahani, M.H., and
Baharvand, H. (2012) The influence of peroxisome proliferator-activated receptor γ(1) during
differentiation of mouse embryonic stem cells to neural cells. Differentiation 83(1), 60-7.
Seifi, T., Ghaedi, K., Salamian, A., Tanhaei, S., Safari, F., Hojati, Z., Tavassoli, M.,
Baharvand, H., and Esfahani, M.H. (2012) Amplification of GC-rich putative mouse PeP promoter
using betaine and DMSO in ammonium sulfate polymerase chain reaction buffer. Avicenna Journal
of Medical Biotechnology 4(4), 206-9.
Lachinani, L., Ghaedi, K., Tanhaei, S., Salamian, A., Karamali, F., Kiani-Esfahani, A.,
Rabiee, F., Yaghmaei, P., Baharvand, H., and Nasr-Esfahani, M.H. (2012) Characterization and
Functional Assessment of Mouse PPARγ1 Promoter. Avicenna Journal of Medical Biotechnology
4(4), 160-9.
Orangy, E., Hojati, Z., Ghaedi, K., Tabatabaeean, M. (2012) Comparison of the HER2/neu
gene amplification assesment by differential PCR and immunohistochemistry in breast cancer
patients in Isfahan. Journal of Shahrekord University of Medical Sciences 13(5), 71-82. (Persian)
Sanei Ata-Abadi, N., Ghaedi, K., Dormiani, K., Khazaie, Y., Forouzanfar, M., Tavassoli,
M., and Nasr-Esfahani, M.H. (2012) Conctruction of a minicircle DNA encompassing Pouromycin
resistance gene. Genetics in the 3rd Millennium 9(4), 2566-2573. (Persian).
Dehdashtian, Z., Vahabi, M.R., Fazilati, M., Ghaedi, K., and Salamian, A. (2011) Study on
genetic variation of Astragalus gossypinus Fisher populations in Isfahan province. Genetics in the
3rd Millennium 9(3), 2474-2480. (Persian).
Shabani, K., Ghaedi K., Tanhaie, S., Karbalaie, K., Salamian, A., Rabiee, F., Farrokhi, A.,
Nasr-Esfahani, M.H., and Baharvand, H. (2011) Increased expression of PPARγ1 in the
differentiation of mouse embryonic stem cells into definitive endoderm. Genetics in the 3rd
Millennium 9(3), 2533-2543.
Jafarpour, F., Hosseini, S.M., Hajian, M., Forouzanfar, M., Ostadhosseini, S., Abedi, P.,
Gholami, S., Ghaedi, K., Gourabi, H., Shahverdi, A.H., Vosough, A.D., and Nasr-Esfahani, M.H.
(2011) Somatic cell-induced hyperacetylation, but not hypomethylation, positively and reversibly
affects the efficiency of in vitro cloned blastocyst production in cattle. Cellular Reprograming 13(6),
483-93.
Aghajanpour, S., Ghaedi, K., Salamian, A., Deemeh, M.R., Tavalaee, M., Moshtaghian, J.,
Parrington, J., and Nasr-Esfahani, M.H. (2011) Quantitative expression of phospholipase C zeta, as
an index to assess fertilization potential of a semen sample. Human Reproduction 26(11), 2950-6.
Ganjalikhani Hakemi, M., Ghaedi, K., Andalib, A., Hosseini, M., and Rezaei, A. (2011)
Optimization of human Th17 cell differentiation in vitro: evaluating different polarizing factors. In
Vitro Cellular & Developmental Biology – Animal 47(8), 581-92.
15
Nasr-Esfahani, M.H., Hosseini, S.M., Hajian, M., Forouzanfar, M., Ostadhosseini, S., Abedi,
P., Khazaie, Y., Dormiani, K., Ghaedi, K., Forozanfar, M., Gourabi, H., Shahverdi, A.H., Vosough,
A.D., and Vojgani, H. (2011) Development of an optimized zona-free method of somatic cell
nuclear transfer in the goat. Cellular Reprogramming 13(2), 157-70.
Ostadsharif, M., Ghaedi, K., Nasr-Esfahani, M.H., Mojbafan, M., Tanhaie, S., Karbalaie, K.,
and Baharvand, H. (2011) The expression of peroxisomal protein transcripts increased by retinoic
acid during neural differentiation. Differentiation 81(2), 127-32.
Honsho, M., Hashiguchi, Y., Ghaedi, K., and Fujiki, Y. (2011) Interaction defect of the
medium isoform of PTS1-receptor Pex5p with PTS2-receptor Pex7p abrogates the PTS2 protein
import into peroxisomes in mammals. Journal of Biochemistry 149(2), 203-10.
Shadanloo, F., Najafi, M.H., Hosseini, S.M., Hajian, M., Forouzanfar, M., Ghaedi, K.,
Abedi, P., Ostadhosseini, S., Hosseini, L., Eskandari-Nasab, M.P., and Nasr-Esfahani, M.H. (2010)
Sperm status and DNA dose play key roles in sperm/ICSI-mediated gene transfer in caprine.
Molecular Reproduction and Development 77(10), 868-75.
Nasr-Esfahani, M.H., Abbasi, H., Mirhosseini, Z., Ghasemi, N., Razavi, S., Tavalaee, M.,
Tanhaei, S., Deemeh, M.R., Ghaedi, K., Zamansoltani, F., and Rajaei, F. (2010) Can altered
expression of HSPA2 in varicocele patients lead to abnormal spermatogenesis? Yakhteh Medical
Journal 4(3), 104-113.
Hatami-Baroogh, L., Razavi, S., Zarkesh-Esfahani, H., Tavalaee, M., Tanhaei, S., Ghaedi,
K., Deemeh, M.R., Rabiee, F., and Nasr-Esfahani, M.H. (2010) Evaluation of the leptin receptor in
human spermatozoa. Reproductive Biology and Endocrinology 8:17.
Ghaedi, K., Uemura, H. & Fujiki, Y. (2009) Isolation and characterization of a new
peroxisome deficient CHO mutant cell belonging to complementation group 12. Journal of Sciences
Islamic Republic of Iran 20(3), 1016-1104.
Ghasemi, S., Ghaedi, K., Nasr Esfahani, M.H., Esmaeeli, A., Tanhaie, S., Rabeei, F.,
Karbalaii, K. & Baharvand, H. (2009) Transfection of mouse PPARgamma1 cDNA in to the
bovine fibroblast cells and analysis of its intracellular expression using EGFP gene reporter. Journal
of veterinary medicine 3(6), 1-6. (Persian).
Ostadsharif, M., Ghaedi, K., Nasr Esfahani, M.H., Tanhaie, S., Karbalaii, K., Parivar, K. &
Baharvand, H. (2009) Cytosolic localization of mouse peroxisomal protein/ΔSKI fused with
enhanced green fluorescent protein into Chinese hamster ovary-K1 and P19 cells. Yakhteh Medical
Journal 11(2), 154-159. (Persian).
Tanhaie, S., Ghaedi, K., Karbalaii, K., Razavi, S., Ostadsharif, M., Nazari-Jahantigh, M.,
Rabeei, F., Nematollahi, M., Baharvand, H. & Nasr Esfahani, M.H. (2009) Mouse peroxisomal
protein cDNA cloning and characterization of its intraclleular localization. Yakhteh Medical Journal
11(2), 196-203. (Persian).
Eghbalsaied, S., Ghaedi, K., Forouzanfar, M., Hajian, M., Hosseini, M. &
Nasr Esfahani, M.H. (2009) Science and Technology of Farm Animal Transgenesis. Yakhteh
Medical Journal 11(2), 78-87 (Persian).
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Eghbalsaied, S., Ghaedi, K., Hosseini, M., Tanhaie, S., Forouzanfar, M., Hajian, M.,
Mozafari, NA. & Nasr Esfahani, MH. (2009) Selection of the most appropriate medium for
assessing motility and DNA uptake of bovine spermatozoa. Yakhteh Medical Journal 10 (4): 266-71.
Nazari Jahantigh, M., Ghaedi, K., Nasr Isfahani, MH., Tanhaei, S., Rabiee, F., Karbalaei, K.,
Ostad Sharif, M., Nematollahi, M., Baharvand, H., Razavi, S., & Miroliaei, M. (2008) Intracellular
localization of FLAG-peroxisomal protein in Chinese Hamster Ovary (CHO) cells. Iranian Journal
of Biotechnology 6 (3): 174-180.
Salamian, A., Ghaedi, K., Razavi, S., Tavalaee, M., Tanhaei, S., Tavalaee, M., salahshouri,
I., Gourabi, H. & Nasr-Esfahani, MH. (2008) Single nucleotide polymorphism analysis of protamine
genes in infertile men. International Journal of Fertility and Sterility 2(1): 13-18
Ghaedi, K., Fujiki, Y. (2008) Isolation and characterization of novel phenotype CHO cell
mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent. Cell
Biochemistry & Function 26, 1-8.
Mobini-Dehkordi, M., Nahvi,I.,Zarkesh-Esfahani, H., Ghaedi, K., Tavassoli, M., Akada. R.
(2008) Isolation of a novel mutant strain of Saccharomyces cerevisiae by an Ethyl Methane
Sulfonate-induced mutagenesis approach as a high producer of bioethanol. Jouranl of Bioscience
and Bioengineering 105, 403-8.
Ghodratnama, R., Karbalaii, K., Ghaedi, K., Baharvand, H. & Nasr-Esfahani, M. (2007)
Optimization of PTS2-EGFP expression in CHO and Vero cells. Yakhteh medical journal 9, 170-5.
Ghaedi, K., Nassiri, I. (2007) Molecular characterization of peroxisome biogenesis disorders
with Zellweger syndrome spectum. Iranian Journal of Pediatrics 17, 275-282.
Mobini-Dehkordi, M., Nahvi, I., Ghaedi, K., Tavassoli, M. (2007) Isolation of high ethanol
resistant strains of Saccharomyces cerevisiae. Research in Pharmaceutical Sciences 1, 85-91.
Fujiki, Y., Okumoto, K., Kinoshita, N., Ghaedi, K. (2006) Lessons fom peroxisome-
deficient Chinese hamster ovary (CHO) cell mutants. Biochimica et Biophysica Acta 1763, 1374-81.
Akiyama, N., Ghaedi, K., and Fujiki, Y. (2002) A novel pex2 mutant: catalase-deficient but
temperature-sensitive PTS1 and PTS2 import. Biochemical and Biophysical Research
Communications 293, 1523-9.
Fujiki, Y., Otera, H., and Ghaedi, K. (2002) peroxisome biogenesis and human disorders.
Experimental Medicine (Jikken Igaku) 20, 987-993. (Japanese).
Mukai, S., Ghaedi, K., and Fujiki, Y. (2002) Intracellular localization, function, and
dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells. Journal
of Biological Chemistry 277, 9548-9561.
Ghaedi, K., Honsho, M., Shimozawa, N., Suzuki, Y., Kondo, N., and Fujiki, Y. (2000)
PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger
syndrome of complementation group G. The American Journal of Human Genetics 67, 976-981.
Otera, H., Harano, T., Honsho, M., Ghaedi, K., Mukai, S., Tanaka, A., Kawai, A., Shimizu,
N., and Fujiki, Y. (2000) The mammalian peroxin Pex5pL, the longer isoform of the mobile
17
peroxisome targeting signal (PTS) type 1 transporter, translocates the Pex7p.PTS2 protein complex
into peroxisomes via its initial docking site, Pex14p. Journal of Biological Chemistry 275, 21703-14.
Ghaedi, K., Tamura, S., Okumoto, K., Matsuzono, Y., and Fujiki, Y. (2000) The peroxin
Pex3p initiates membrane assembly in peroxisome biogenesis. Molecular Biology of the Cell 11,
2085-2102.
Shimozawa, N., Suzuki, Y., Zhang, Z., Imamura, A., Ghaedi, K., Fujiki, Y., and Kondo,
N. (2000) Identification of PEX3 as the gene mutated in a Zellweger syndrome patient lacking
peroxisomal remnant structures. Human Molecular Genetics 9, 1995-1999.
Ghaedi, K., Kawai, A., Okumoto, K., Tamura, S., Shimozawa, N., Suzuki, Y., Kondo, N.,
and Fujiki, Y. (1999) Isolation and characterization of novel peroxisome biogenesis-defective
Chinese hamster ovary cell mutants using green fluorescent protein. Experimental Cell Research
248, 489-497.
Ghaedi, K., Itagaki, A., Toyama, R., Tamura, S., Matsumura, T., Kawai, A., Shimozawa,
N., Suzuki, Y., Kondo, N., and Fujiki, Y. (1999) Newly identified Chinese hamster ovary cell
mutants defective in peroxisome assembly represent complementation group A of human
peroxisome biogenesis disorders and one novel group of mammals. Experimental Cell Research
248, 482-488.
Shimizu, N., Itoh, R., Hirono, Y., Otera, H., Ghaedi, K., Tateishi, K., Tamura, S., Okumoto,
K., Harano, T., Mukai, S., and Yukio Fujiki, Y. (1999) The Peroxin Pex14p. cDNA cloning by
functional complementation on a Chinese hamster ovary cell mutant, characterization, and
functional analysis. Journal of Biological Chemistry 274, 12593-12604.
Matsuzono, Y., Kinoshita, N., Tamura, S., Shimozawa, N., Hamasaki, M., Ghaedi, K.,
Wanders, R.J.A., Suzuki, Y., Kondo, N., and Fujiki, Y. (1999) Human PEX19: cDNA cloning by
functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential
role in peroxisomal membrane assembly. Proceedings of the National Academy of Sciences USA 96,
2116-2121.
Kinoshita, N., Ghaedi, K., Shimozawa, N., Wanders, R.J.A., Matsuzono, Y., Imanaka, T.,
Okumoto, K., Suzuki, Y., Kondo, N., and Fujiki, Y. (1998) Newly identified Chinese hamster ovary
cell mutants are defective in biogenesis of peroxisomal membrane vesicles (peroxisomal ghosts),
representing a novel complementation group in mammals. Journal of Biological Chemistry 273,
24122-24130.
GRANTS AND FUNDING:
1. Direct Supervisor of the ongoing Project: Transdifferentiation of human keratinocytes and
fibroblast cells to motor neuron cells using small molecules (SAG and DSM). Awarded by:
Stem Cell Science and Technology Council, Vice- Presidency of The Islamic republic of Iran
for Science and Technology (150 million I.R. Rials equal to $10000 US)
2. Direct Supervisor of the ongoing Project: Anti-tumor activity assessments of plants
cyclotides on cancer stem cells. Awarded by: Iran National Science Foundation, Vice-
Presidency of The Islamic republic of Iran for Science and Technology (200 million I.R. Rials
equal to $15000 US)
18
3. Direct Supervisor of the ongoing Project: non-coding RNA activity assessments during
differentiation of TH17 cells. Awarded by: National Institute for Medical Research
Development (NIMAD) (700 million I.R. Rials equal to $30000 US)
MEETINGS:
Contribution in more than 450 Poster and oral Presentations.
EDITORIAL BOARD MEMBERSHIP:
1. Research in Pharmaceutical Sciences
2. International Journal of Fertility and Sterility
3. ISRN Molecular Biology
4. Niche
5. Multiple Sclerosis & Neuroimmunology
6. Dataset Papers in Science
BOOKS:
1. Movahedian, A., Ghaedi, K., and Khademizadeh, M. (2007) A review to The Graduate Entrance
Examinations of Biochemistry for Universities of Medical Sciences. Golbon Publication, Isfahan,
Iran. (Persian).
2. Khademizadeh, M., Movahedian, A., and Ghaedi, K. (2011) Peroxisomes and Peroxisomal
disorders. Kankash Publication, Isfahan, Iran. (Persian).
3. Rahgozar, S., and Ghaedi, K. (2014) Stem Cells and Tissue Regeneration. University of Isfahan
Publication, Isfahan, Iran. (Persian).
4. Momtazi Borujeni, A.A., Ghaedi, K., and Mirian, M. (2014) The Foundation of Molecular
Biology. Academic Center for Education and Culture Research Press, Isfahan, Iran. (Persian).
5. Samani, S., Samani, R., Ghaedi, K., Azadeh, M. (2016) An Introduction to Experimental
Activities in Clinical and Molecular Laboratories. Academic Center for Education and Culture
Research Press, Isfahan, Iran. (Persian).
BOOKS TRANSLATIONS:
1. Ghaedi, K., Roughanian, R., Aftabi, Y., and Fattahi, M. (2009) University of Isfahan Press,
Isfahan, Iran. (Persian Translation): Molecular Genetics of Bacteria. 4th edition. Jeremy W.
Dale and Simon F. Park. (2003) University of Surrey, UK. A John Wiley & Sons, Ltd. [Our
translation received; The tenth award seasonal book for best translation (Summer of 2010)].
2. Seifi, T., Momtazi Borujeni, A.A., and Ghaedi, K. (2014) Academic Center for Education
and Culture Research Press, Isfahan, Iran. (Persian Translation): An Introduction to Genetic
Engineering. Third edition. Desmond T. Nicholl. (2008) Cambridge University Press, UK.
REVIEW AND ASSESSMENT ACTIVITIES:
19
110 Cases of Master Degree Theses
38 Cases of PhD. Dissertations
14 Cases of Sabbatical Projects
69 Cases of Research Projects
23 Cases of Endowed Professorships and Associate Professorships
19 Cases of Awards
8 Cases of Meetings
179 Cases of Papers
12 Cases of Books
SUPERVISING AND ADVISING OF GRADUATE THESES
113 Cases of Master Degree Theses (Supervising)
39 Cases of Master Degree Theses (Advising)
25 Cases of PhD. Theses (Supervising)
18 Cases of PhD. Theses (Advising)
LANGUAGES:
Persian
English
Japanese
