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Appropriate Technologies
Paul LaBarre, MME, RACPaul LaBarre, MME, RACPaul LaBarre, MME, RACPaul LaBarre, MME, RAC
1111stststst Global Forum on Medical DevicesGlobal Forum on Medical DevicesGlobal Forum on Medical DevicesGlobal Forum on Medical Devices
September 10, 2010September 10, 2010September 10, 2010September 10, 2010
Bangkok, ThailandBangkok, ThailandBangkok, ThailandBangkok, Thailand
Appropriate Technologies
Appropriate
Appropriate…often means simple
Nevirapine Infant Dose PouchNevirapine Infant Dose PouchNevirapine Infant Dose PouchNevirapine Infant Dose Pouch
Appropriate…often means simple
Appropriate…often means not so simple
Appropriate Technologies
Appropriate = metrics-driven
Innovations in Vaccine DeliveryInnovations in Vaccine DeliveryInnovations in Vaccine DeliveryInnovations in Vaccine Delivery
Appropriate = metrics-driven
Health (in)equityHealth (in)equityHealth (in)equityHealth (in)equity
48
6573
Life Expectancy
148
59
29
Infant Mortality
210
78
37
Under-five Mortality
Decreasing in 16 countries
10 times worse indeveloping countries
27% are underweight
1955
1995
2025
Source: World Health Report 1998, World Health Organization
““““MetricsMetricsMetricsMetrics””””
Life expectancyLife expectancyLife expectancyLife expectancy
Infant mortalityInfant mortalityInfant mortalityInfant mortality
UnderUnderUnderUnder----five mortalityfive mortalityfive mortalityfive mortality
Fertility rateFertility rateFertility rateFertility rate
Maternal death rateMaternal death rateMaternal death rateMaternal death rate
““““MetricsMetricsMetricsMetrics”””” = Aggregated personal stories= Aggregated personal stories= Aggregated personal stories= Aggregated personal stories
Life expectancyLife expectancyLife expectancyLife expectancy
Infant mortalityInfant mortalityInfant mortalityInfant mortality
UnderUnderUnderUnder----five mortalityfive mortalityfive mortalityfive mortality
FertilityFertilityFertilityFertility
Maternal deathsMaternal deathsMaternal deathsMaternal deaths
Appropriate = metrics driven
Appropriate = metrics driven
Appropriate = needs driven
Appropriate = needs driven
Appropriate = user-centerediterative
.
design
SILCS Diaphragm: SILCS Diaphragm: SILCS Diaphragm: SILCS Diaphragm: ““““One Size Fits ManyOne Size Fits ManyOne Size Fits ManyOne Size Fits Many””””
Firm
insertion
edge
Grip dimples
Cervical cup
membrane
Finger-tip
removal dome
Side viewTop view
Appropriate = user-centered
Appropriate = less expensive
Appropriate = less expensive
Appropriate =infrastructure
dependent
Blood banksBlood banksBlood banksBlood banks
Appropriate =infrastructure
….dependent
Appropriate =infrastructure
….dependentin
Infectious Disease IVDInfectious Disease IVDInfectious Disease IVDInfectious Disease IVD
Molecular Diagnostics
Reach >>>DecentralizedCentralized<<<Centralized<<<Centralized<<<Centralized<<<
Accu
rac
yMolecular
Diagnostics
Point of
Care Dx
ELISA
Western Blot
Lateral Flow
Agglutination
TMA
Next Gen
NAT
PCR
POC
Microscopy
Infectious Disease IVDInfectious Disease IVDInfectious Disease IVDInfectious Disease IVD
Molecular Diagnostics
Reach >>>DecentralizedCentralized<<<Centralized<<<Centralized<<<Centralized<<<
Accu
rac
yMolecular
Diagnostics
Point of
Care Dx
ELISA
Western Blot
Lateral Flow
Agglutination
TMA
Next Gen
NAT
PCR
POC
Microscopy
NINA
Appropriate =infrastructure
….dependentin
Appropriate =infrastructure
….modifying
Appropriate =
multiple,
complementary
options
Photo: Suellen Miller
Appropriate ≠≠≠≠high
return on
investment
Appropriate = risky
PATHPATHPATHPATH’’’’s role in product development partnershipss role in product development partnershipss role in product development partnershipss role in product development partnerships
Risk-return
threshold
Private sector
Low resource settings
risk/return ratio
Potential returns
De
velo
pm
en
t ri
sk
PDPs engage private sector to create public benefit by mitigating risks.
Potential returns
De
velo
pm
en
t ri
sk Risk-return
threshold
Private sector
Pub
lic b
enef
it
PDP
Low resource settings
risk/return ratio
PATHPATHPATHPATH’’’’s role in product development partnershipss role in product development partnershipss role in product development partnershipss role in product development partnerships
PATH MissionPATH MissionPATH MissionPATH Mission
Improve the health
of people around
the world by
advancing
technologies,
strengthening
health systems and
encouraging healthy
behaviors.
Ric
hard
Lord
PartnershipsPartnershipsPartnershipsPartnerships
““““The problems we face The problems we face The problems we face The problems we face
cannot be solved by the cannot be solved by the cannot be solved by the cannot be solved by the
same level of thinking same level of thinking same level of thinking same level of thinking
that created them.that created them.that created them.that created them.””””
- attributed to Albert Einstein
Thank you!
Paul LaBarre, MME, RACPaul LaBarre, MME, RACPaul LaBarre, MME, RACPaul LaBarre, MME, RAC
[email protected]@[email protected]@path.org
