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0 Tube – like structure
0 Includes: Gastrointestinal (GI) Tract or Alimentary Canal – mainly the mouth, pharynx(throat), esophagus(food tube leading to stomach), stomach and the small and large intestines. Also includes accessory structures such as teeth and tongue.
0 System for mastication, digestion and absorption.
9/23/2012 Alona Rose L. Jimenea 2
Microbial Diseases of Digestive System
Structure and Function of the Digestive System
0 Each milliliter of saliva contain millions of bacteria
0 Stomach and small intestine have few microorganisms; limited by hydrochloric acid produced by stomach
0 In contrast large intestine has enormous microbial populations; exceeding 1oo billion bacteria per gram feces
9/23/2012 Alona Rose L. Jimenea 3
Microbial Diseases of Digestive System
Normal Microbiota of the Digestive System
Microbial Diseases of Digestive System
9/23/2012 Alona Rose L. Jimenea 4
Dental Caries (tooth decay)
0 Mainly caused by accumulations of masses of microorganismsand their products; dental plaque – type of biofilm and areintimately involve in the formation of dental caries.
9/23/2012 Alona Rose L. Jimenea 5
Microbial Diseases of Digestive System
0 Characterized by inflammation and degeneration of structures that supportsthe teeth.
0 Cementum: specialized connective tissue that covers the roots of the teeth.0 Gingivitis: infection restricted to the gums.0 Periodontitis: gums are inflamed and bleed easily. [Prophyromonas]0 Acute necrotizing ulcerative gingivitis/ Vincent’s disease/Trench Mouth :
makes normal chewing difficult , foul breath [Prevotella intermedia]
Periodontal Disease
9/23/2012 Alona Rose L. Jimenea 10
Microbial Diseases of Digestive System
0 Mumps: swelling of parotid glands
0 Testes may become inflamed: orchitis.