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Fe++
Fe++
Fe++
Intestine
Fe++
absorption 15-20 %
Heme iron is easily absorbed as a whole
structure with high bio-availability.
Non-heme iron must be dissolved
before uptake. Because of low
absorption reactive free iron ions
remain in the gut.
Fe++
Fe++
Fe++
Fe++
Fe++
absorption 2-4 %
Intestine
Fe++
Iron in food Bone marrow Hemoglobin Menstrua2on (other bleedings)
Heme iron Serum iron Hemolysis Urine Non-‐heme iron Bile (faeces) Free iron Fe++ Intes2ne cells
Faeces All cells Cell apoptosis Excreted cells
Sweat
1 mg/day
Iron metabolism in the body
INTAKE USAGE EXCRETION