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Welcome to Institut Pasteur! - Paris Nash

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Page 1: Welcome to Institut Pasteur! - Paris Nash
Page 2: Welcome to Institut Pasteur! - Paris Nash

Welcome to Institut Pasteur!

Stanislas Pol, MD, PhD

Liver Department, Hôpital Cochin

Inserm U-1213 & Center for Translational Science, Institut Pasteur

Université Paris Descartes, Paris, France

[email protected]

[email protected]

Page 3: Welcome to Institut Pasteur! - Paris Nash

Institut Pasteur: a research institute

4 missions to serve scientific progress and health

• Research

• An international research institute of excellence in medicine, clinical

research and public health

• Health and public health

• A mission of public health with (15 CNR et 9 CCOMS) at national and

international levels (health watch, alerts and interventions)

• Education

• A teaching and training centre

• Research applications

Technology transfer and industrial relations

Page 4: Welcome to Institut Pasteur! - Paris Nash

Institut Pasteur: a research institute An original economic model: Independence in

research directions and reactivity

€296.4 M Current income in 2014

€88.2 M Research

contracts and

agreements

€39.6 M Industrial

royalties

€18.1 M€ External services

€145.9 M

Revenue from

own activities

49.2%

€87.1 M

Public gifts & donations

and revenues from

assets

€54.8 M

French Ministry of

Research

29.4%

€33.3 M Donations

€17.3 M Legacies

€35.3 M Revenues from assets

€1.2 M Apprenticeship tax

€3.5 M French Institute for

Public Health

Surveillance (InVS)

€58.3 M€

Government

contributions

19.7% 1.7%

€5.1 M

€5.1 M

Other income

The Institut Pasteur is a nonprofit organization and relies on the generosity and support of the public to carry out its research programs.

Page 5: Welcome to Institut Pasteur! - Paris Nash

Institut Pasteur: a research institute

• Pr Christian Bréchot

- Director of IP: 2013-2017

- EASL secretary

- Very famous Hepatologist:

HBV:

first genomic diagnosis (Hybridotest)

first demonstration of direct hepatocarcinogenesis

Page 6: Welcome to Institut Pasteur! - Paris Nash

Institut Pasteur: a research institute

11 departments in Paris 33 institutes in the Network

Vir

olo

gy

De

ve

lop

me

nt

Neu

roscie

nces

Gen

om

es

Etc

.

Cam

bo

dia

Sen

eg

al

Mo

rocco

Cam

ero

on

Etc

.

2015 : Creation of transversal centers

4

Page 7: Welcome to Institut Pasteur! - Paris Nash

Institut Pasteur: An international institute at the

very heart of Paris

130

research

units 2,500

employees

650 scientists

4 transversal

research

centers

1,000

Ph students

and

postdocs

per year

11 scientific

departments

more than

60

nationalities

A 55,000 m2 campus

14

technological

platforms

Page 8: Welcome to Institut Pasteur! - Paris Nash

Center for translationnal science

An integrated view of translational research: « guichet unique »

Page 9: Welcome to Institut Pasteur! - Paris Nash

Center for translationnal science

An integrated view of translational research: « guichet unique »

Hospital Bedside

Translation

Research

Lab Bench

Page 10: Welcome to Institut Pasteur! - Paris Nash

Center for translationnal science

Page 11: Welcome to Institut Pasteur! - Paris Nash

Center for translationnal science

JRT Séminaire techno

(CRT-TC)

Matinales (CRT-CC) ¼ h Med ¼ h Science

Rassembler les acteurs de la rech.

translationnelle

Informer sur les nouvelles technologies

Informer sur la recherche clinique

Donner une culture médicale aux chercheurs

Faire connaître la recherche de l'IP dans

les hôpitaux

1/an (200p) 8/an (8p) 5/an (30p) 20/an (50p) 5/an à l’hôpital (10p)

Clémentine Schilte

Breakthrough session Storm

Patients et chercheurs (avec CRT-IB) Évènement social

Faciliter de nouvelles collaborations avec le

réseau

Rassembler médecins et chercheurs sur une

thématique

Réflexion sur la place des patients dans la recherche

Créer des liens entre médecins et chercheurs

1/an (100p) 1 ou 2/an (40p) 1/an (80p) 1/an (50p)

Page 12: Welcome to Institut Pasteur! - Paris Nash

NASH: A multidisciplinary translationnal topic

- Hepatologist/Endocrinologist/Cardiologist/Nutritionnist/Surgeons… - Scientists of liver disease, metabolism pathways, imaging…

Page 13: Welcome to Institut Pasteur! - Paris Nash

NASH: A multidisciplinary translationnal topic

Rinella, Nature rev. 2016

Unmet needs

- Noninvasive diagnosis of NASH

- Biomarkers of

progression of fibrosis

- Combination therapies

- Hepatologist/Endocrinologist/Cardiologist/Nutritionnist/Surgeons… - Scientists of liver disease, metabolism pathways, imaging…