U.S. Bone Growth and Spinal Fusion Stimulator Markets

Rapid Growth in Stimulator Market in Recent Years Driven by Quest for Less-invasive Treatment Options

“Physicians are exhibiting a renewed interest in bone growth and spinal fusion stimulators due to better product designs, stronger reimbursement, and the desire

for adjunctive treatments that improve the success of spinal fusions and the healing of difficult fractures."

Medical Devices Analyst Team

Frost & Sullivan

• Development of biologic treatments overlaps with stimulation providing opportunities and threats

• New applications of PEMF technology allow manufacturers to leverage it into new markets

• Application of stimulators to cervical spinal fusion holds significant revenue potential

• Increasing number of spinal fusion procedures boosts sales of spinal fusion stimulators

• Better stimulator designs improve patient compliance and therapeutic benefits leading to increased market revenues

Industry Trends

• New distribution agreements with top orthopedic companies fuel expansion of stimulator market revenues

• Swelling population of older Americans leads to increased need for stimulation

• Growing number of spinal surgeons practicing, boosts equipment sales

• Increased use of instrumentation in trauma fixation and spinal fusion surgery leads to improved success rates without stimulators limiting market revenues

Industry Trends (cont’d)

Frost & Sullivan provides:

• Detailed insights into recent developments and trends

• Drivers, restraints, challenges, and strategic recommendations

• Analyst insights on ‘hot topics” and emerging applications in the Bone Growth and Spinal Fusion Stimulator Market

• Market sizing and competitive analysis

• Market forecasts and opportunity analysis

• Detailed revenue breakdowns for both bone growth and spinal fusion stimulators in both external and implantable designs

• Detailed discussion of emerging applications for PEMF technology and stimulation synergies with orthobiologics

Key Features

• Coverage of United States market which generates the vast majority of revenues in the bone growth and spinal fusion stimulator market

• Proven methodology encompassing extensive primary and secondary data and research

• Focused information and strategies that cover business and technology issues

• Credible data and analysis highlighting industry dynamics

• Winning strategies to help you create precise business plans

What We Offer

Current Market Participants• Accurate third-party assessment of market for use in business planning• Assess current and future drivers and restraints• Determine and exploit new application opportunities• Find detailed, market sizing numbers for your own planning needs

New Entrants • Analyze challenges associated with the industry• Learn about winning strategies used by existing competitors• Position yourself to capitalize on the market’s unmet needs• Third-party market estimations for use in business plans

Investment Community• Analyze long-term strategies of companies selling stimulators• Determine which participants will outperform the competition• Assess attractiveness of investing in market

Who Will Benefit?

What’s Included

Bone Growth Stimulators Spinal Fusion Stimulators

ImplantableImplantable ExternalExternal

PEMF/CMFPEMF/CMF/US

Capacitative Coupling

Capacitative Coupling

BREG, Inc. (Distributor) dj Orthopedics, Inc. (Planning to be Distributor in 2003) DePuy Acromed, Inc./ Johnson & Johnson EBI Medical Systems, Inc./ Biomet, Inc. Medtronic Sofamor Danek/ Medtronic, Inc. (Distributor) Orthofix, Inc. OrthoLogic Corp. Smith & Nephew Plc Orthopaedics – Exogen

Key Market Participants

• Call toll free 877 GO FROST

(877.463.7876)

• Fax toll free 888.690.3329

• Email myfrost@frost.com

• Visit www.frost.com

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