RESPIRATORY MEDICINE Volume 91, 1997

W. B. SAUNDERS COMPANY LTD London - Philadelphia * Sydney - Tokyo - Toronto

Number 1 January 1997

Editorial Immunotherapy: a new strategy for tuberculosis control?

J. M. Grange 1

Original Articles i ,

Symptoms related to snoring and sleep apnoea in subjects with chronic bronchitis: report from the Obstructive Lung Disease in

Northern Sweden Study \ L-G. Larsson, B. Lundback, A-C. Jonsson, M. Lindstriim & E. Jonsson 5 n

Immunotherapy with Mycobncterium vaccae in the treatment of tuberculosis in Romania. 1. Newly-diagnosed pulmonary disease

E. Corlan, C. Marica, C. Macavei, J. L. Stanford & C. A. Stanford *smma rc%aBmmBUne

Immunotherapy with Mycobacterium vaccae in the treatment of tuberculosis in Romania. 2. Chronic or relapsed disease

E. Cot-Ian, C. Marica, C. Macavei, J. L. Stanford & C. A. Stanford ~~~~~~~~~~~~

Thalidomide reduces tumour necrosis factor-a production by human alveolar macrophages

J. L. Tavares, A. Wangoo, P. Dilworth, B. Marshall, S. Kotecha & R. J. Shaw (‘~~~~~~~~~~~~~~~~~~~~‘~

Relationship between dyspnoea, pulmonary function and exercise capacity in patients with cystic fibrosis

W. de Jong, C. P. van der Schans, G. P. M. Mannes, W. M. C. van Aalderen, R. G. Grevink & G. H. Koeter ~~~~~~~~~~~

Airway inflammation despite loss of bronchial hyper-responsiveness after multiple ozone exposures

J. Sun & K. Fan Chung

Case Report Distinction between pleural mesothelioma and pulmonary adenocarcinoma using MOC31 in an asbestos sprayer

P. J. Ryan, J. L. Oates, J. Cracker & D. E. Stableforth L

British Association for Lung Research Abstracts Asthma and its pathogenesis - clinical and scientific aspects A.1

II

Number 2 February 1997

Original Articles A reliable method to retrieve Accident & Emergency data stored on a free-text basis

U. N. Premaratne, G. B. Marks, E. J. Austin & P. 0. J. Burney 61 ,

Peripheral blood lymphocyte cell subsets in subjects with chronic obstructive pulmonary disease: association with smoking, IgE

and lung function

J. W. de Jong, 8. van der Belt-Gritter, G. H. Koeter & D. S. Postma II~asmamEma*

67

Body mass index and mortality in patients with severe a,-antitrypsin deficiency N. Seersholm 77

Prevalence of asthma and asthma-like symptoms in Athens, Greece N. Papageorgiou, M. Gaga, C. Marossis, Chr. Reppas, P. Avarlis, M. Kyriakou, S. Tsipra, K. Zeibecoglou & G. Tracopoulos 83

The importance of process variables analysis in the assessment of long-term oxygen therapy by concentrator A. Granados, J. Escarrabill. J. M. Borras & R. Rodriguez-Raisin

i

89

Immunodeficiency in non-tuberculous mycobacterial disease

Case Reports Hard metal lung disease and pneumothorax 2. K. Wahbi, A. G. Arnold &A. J. Newman Taylor 103

Airway stenosis after trachea-bronchial tuberculosis S. Mariotta, L. Guidi, M. Aquilini, R. Tonnarini & A. Bisetti 107

Alveolar haemorrhage revealing epitheloid haemangioendothelioma E. Briens, S. Caulet-Maugendre, B. Desrues, Ml. Quinquenel, H. Lena, B. Turlin & Ph. Delaval

Book Review 115

Letters to the Editor

Number 3 March 1997

Topical Review (A)Symptomatic bronchial hyper-responsiveness and asthma D. F. Jansen, W. Timens, J. Kraan, B. Rijcken 81 D. S. Postma 121

Original Articles Comparison of cytokeratin fragment 19 (CYFRA 21-l) tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA) as

tumour markers in bronchogenic carcinoma M.-S. Huang, S.-B. Jong, M.-S. Tsai, M.-S. Lin, I.-W. Chong, H.-C. Lin & J.-J. Hwang 135

Ventilatory response to positive and negative work in patients with chronic obstructive pulmonary disease J. M. Rooyackers, P. N. R. Dekhuijzen, C. L. A. van Herwaarden & H. T. M. Folgering

Lung auscultation in airway challenge testing A. Purohit, A. Bohadana, M. C. Kopferschmitt-Kubler, L. Mahr, J. Linder & G. Pauli

Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro

A. Gillissen, M. Jaworska, M. Orth, M. Coffiner, P. Maes, E. M. App, A. M. Cantin & G. Schultze-Werninghaus

Case Reports Massive pleural effusion as isolated manifestation of metastatic spread of salivary adenoid cystic carcinoma

W. Torre, M. Comellas & M. Cuesta 169

Bronchiolitis obliterans in a patient with HIV infection

F. Dfaz, J. Collazos, E. Martinez & J. Mayo

Cyclophosphamide in severe steroid-resistant bronchiolitis obliterans organizing pneumonia

I. F. Purcell, S. J. Bourke & S. M. Marshall

Book Review 179

Number 4 April 1997

Topical Review Limitations and promise in the diagnosis and treatment of obstructive sleep apnoea

L. S. Aboussouan, J. A. Golish. D. S. Dinner, M. Strome & W. B. Mendelson B

161

Original Articles

Aetiology of pneumonia following isolated closed head injury

A. Cazzadori, G. Di Perri, S. Vento, S. Bonora, D. Fendt, M. Rossi, M. Lanzafame, F. Mirandola &

Rapid detection of pneumococcal antigen in lung aspirates: comparison with culture and PCR technique

A. Ruiz-Gonzalez, A. Nogues, M. Falguera, J. M. Parcel, E. Huelin & M. Rubio-Caballero

Intensive care management of varicella pneumonia

P. D. Potgieter & J. M. J. Hammond 207 ,m

Allergic bronchopulmonary aspergillosis: the spectrum of computed tomography appearances

N. Panchal, R. Bhagat, C. Pant & A. Shah 213

Effects of smoking and clinical status on lung function in human immunodeficiency virus (HIV)-seropositive subjects

R. N. McCabe, J. Baron, R. Griffin, M. Omogbehin, P. D. Snashall & W. A. Seed 221

Short Report

An assessment of steroid hypersensitivity in asthma

S. M. Wilkinson, B. Higgins, S. Owen, D. L. Mattey & A. Woodcock 231

Case Reports Metastatic large cell lung cancer presenting with numb chin syndrome

M. A. Marinella 235

Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma

T. P. Cotter, N. P. Kealy, P. F. Duggan, A. Curtain & C. P. Bredin 237

Bronchiolitis obliterans organizing pneumonia after adjuvant radiotherapy for breast carcinoma

J. M. van Laar, H. C. Holscher, J. H. J. M. van Krieken & J. Stalk 241

Endobronchial metastasis from rectal adenocarcinoma

Y. C. Lee, C. S. Wong & G. M. Jeffery 245

Number 5 May 1997

Topical Review Nutritional support in advanced pulmonary disease

C. Thomsen

Original Articles Halothane administration during liquid ventilation

D. 6. Kimless-Garber, M. R. Wolfson, C. Carlsson & T. H. Shaffer 255

Effect of alveolar volume on the interpretation of single-breath DLCO

A. Frans, B. Nemery, C. Veriter, L. Lacquet & C. Francis “_

263

The effect of inhaled glucocorticosteroids in emphysema due to a,-antitrypsin deficiency

J. T. R. Wilcke & A. Dirksen 275

Diagnostic strategy for pulmonary tuberculosis in a low-incidence country: Results of chest X-ray and sputum cultured for

Mycobacterium tuberculosis

J. T. R. Wilcke & A. Kok-Jensen 281

The adequacy of oxygenation in patients with hypoxic chronic obstructive pulmonary disease treated with long-term domiciliary

oxygen

D. Morrison, K. M. Skwarski & W. MacNee 287

Overlooked inhaled foreign bodies: late sequelae and the likelihood of recovery

S. A. Al-Majed, M. Ashour, A. F. Al-Mobeireek, M. S. Al-Hajjaj, A. H. Alzeer & K. Al-Kattan

The development of the ‘Quality-of-Life for Respiratory Illness Questionnaire (QOL-RIQ)‘: a disease-specific quality-of-life

questionnaire for patients with mild to moderate chronic non-specific lung disease

A. R. Mail@ C. J. M. Koning, A. H. Zwinderman, L. N. A. Willems, J. H. Dijkman &A. A. Kaptein

The Spacehaler@ for delivery of salbutamol: a comparison with the standard metered-dose inhaler plus Volumatic@ spacer device

K. A. Gunawardena, T. Sohal, J. I. Jones, F. C. Upchurch & 0. K. Crompton

Interleukin-8 and leukotriene B, in bronchoalveolar lavage fluid from HIV-infected patients with bacterial pneumonia

E. Krarup, J. Vestbo, T. L. Benfield & J. D. Lundgren 317

Number 6 July 1997

Topical Review Inflammatory changes in proximal and peripheral airways of asthmatic patients

S. Oddera, M. Silvestri, 0. Sacco, E. Crimi & G. A. Rossi Lm

323

Original Articles Effects of high-dose ipratropium bromide and oral aminophylline on spirometry and exercise tolerance in COPD

E. Cash, F. Mateo 2% C. ‘~~~~~~~~~~~~~ ~~~“iEid~~~~,~~~~~~~~~~~~~~~%~~~~

Lack of effect of nitric oxide inhibition on bronchial tone and methacholine-induced bronchoconstriction in man

M. Maniscalco, M. Sofia, A. Smith, E. A. G. Demoncheaux, M. Mormile, S. Faraone & T. Higenbottam

Influence of inspiratory capacity on bronchodilatation via Turbuhaler@ or pressurized metered-dose inhaler in asthmatic

children: a comparison

Seasonal variation in serum eosinophilic cationic protein (S-ECP) in a general population sample

C. Janson, E. Brnsson, I. Enander L. HBka 347 *xm wmbmcs 8t%%awm

Pulmonary microvascular injury following general anaesthesia with volatile anaesthetics ~ halothane and isoflurane: a comparative

clinical and experimental study

Evaluation of response to chemotherapy in patients affected with non-small cell lung cancer by means of three tumour markers

elaborated by discriminant analysis

G. Paone, G. De Angelis, S. Greco, L. Portalone, L. De Marchis, G. Galluccio, A. Taglienti, A. Bisetti & F. Ameglio 361

‘~~1’5;~~~IP~iP~~~~~~~~

Technical Note Evaluation of a pocket-sized turbine spirometer for clinical use with children

K. P. Paul & T. Schultz mmmimwm mmm m!xx”lnpwasY

369

Case Reports

Post-traumatic pleural effusion: demonstration of local complement consumption

F. de Blay, A. Aykut-Baturalp, J. Goetz, A. Purohit, A. Perez-lnfante, G. Hauptmann & G. Pauli 373

A case of rapidly expanding tuberculous lung cavity after bronchoscopy

K. W. T. Tsang, B. Jones & 1. P. F. Mungall 377 .m.wLlsi6I

Inflammatory pseudotumour of the lung presenting as an airway obstructive syndrome M. Calderazzo, A. Gallelli, V. Barbieri, F. Roccia, G. Pelaia. C. M. E. Tranfa, S. Cavaliere & F. Zori 381

385

Number 7 August 1997

Original Articles

Phase 1 safety trial of Filgrastim (r-metHuG-CSF) in non-neutropenic patients with severe community-acquired pneumonia B. P. deBoisblanc, C. M. Mason, J. Andresen, E. Logan, M. B. Bear, S. Johnson, J. Shellito, W. Ft. Summer & S. Nelson 387

Bronchiectasis in Finland: trends in hospital treatment 0. Sayntijakangas, T. Keistinen. T. Tuuponen & S-L. Kivala 395 w

Serum angiotensin converting enzyme does not correlate with radiographic stage at initial diagnosis of sarcoidosis A. F. Shorr, K. G. Torrington & J. M. Parker

Artificial pneumothorax by the Veress cannula: efficacy and safety P. Faurschou & K. Viskum ii

399

402

Thickness of the basement membrane of bronchial epithelial cells in lung diseases as determined by transbronchial biopsy K. Watanabe, S. Senju, H. Toyoshima & M. Yoshida

Hospitalization of adults for asthma and inhaled corticosteroid use in an island population J. M. Cacciottolo M. V. Balzan &

Asthma statistics in the Netherlands 1980-94 J. mu

Phase II study of weekly gemcitabine in advanced non-small cell lung cancer

Contemporary use of antibiotics in 1089 adults presenting with acute lower respiratory tract illness in general practice in the U.K.: implications for developing management guidelines

J. Macfarlane, S. A. Lewis, R. Macfarlane & W. Holmes

Case Reports

427

Invasive pulmonary aspergillosis with cerebromeningeal involvement after short-term intravenous corticosteroid therapy in a patient with asthma

E. Monlun F. de Bla Eli:

A case of acute deterioration in asthma symptoms induced by isoniazid prophylaxis

Book Review

Errata

441

442

Number 8 September 1997

Original Articles Reduced forced expiratory flow in schoolchildren with respiratory symptoms: The Odense Schoolchild Study

G. Mostgaard, H. C. Siersted, H. S. Hansen, N. Hyldebrandt & H. Oxhej

The long-term efficacy and safety of two different corticosteroids in chronic sarcoidosis

G. Rizzato, A. Riboldi, 8. Imbimbo, A. Torresin & S. Milani

The prevalence of self-reported asthma and respiratory symptoms in Ankara, Turkey

Y. Saraplar, F. Cetinkaya, A. Tuncer, 8. Kalayci, G. Adalioglu, B. E. Sekerel, Y. Demirel & 2. Misirhgil ~~~~~~“,~~~,~~ &“_ir#m inwnm ~~~~.~*~~~~~~~~~~ xBmm a&as

Low IgG subclass levels in brittle asthma and in patients with exacerbations of asthma associated with respiratory infection

J. G. Ayres & R. A. Thompson ‘w!l~~~~~m Yli*lllQ:{rzs ~n~,p~~,~mi~~*~~wj cm-w

The diagnostic value of cold air hyperventilation in adults with suspected asthma

H. 0. Koskela, S. H. Fbis%inen & H. 0. Tukiainen

461

464

0 ‘0

The single-breath nitrogen test in coal miners: factors associated with failure to perform

u, I. , M. Ma Ph ~mmwm?8

Genetic relatedness of Burkholderia (Pseudomonas) cepaciu isolates from five cystic fibrosis centers in Michigan

A. Kumar, S. Dietrich, W. Schneider, R. Jacobson, F. Pouch Downes, B. E. Robinson-Dunn, R. Honicky, J. Martin

Case Reports Multiple pulmonary nodules in association with pyoderma gangrenosum

I. Kasuga, N. Ya gisawa, C. Takeo, M. Koga, H. Ki emar ~~~~~~~~~~,~~~~~~~~

Tracheobronchopathia osteochondroplastica presenting at the time of a difficult intubation

tmeur, G. Bovyn, P. Leroux & Niel-Duriez ~~~~~~~~~~~~0811~~l631018~~~~1

3 ”

496

Tracheobronchopathia osteochondroplastica

C. N. Meyer, M. Dessing & H. Broholm ~~~‘~~~~~~~~~

Multiple tracheal strictures following mechanical ventilation

M. R. Partridge & P. Flood-Page

Number 9 October 1997

Topical Review Propofol for sedation in the intensive care unit: essentials for the clinician

M. A. Marinella

Original Articles Hepatocyte growth factor and neutrophil elastase in idiopathic pulmonary fibrosis

S. Hojo, J. Fujita, T. Yoshinouchi, H. Yamanouchi, T. Kamei, I. Yamadori, Y. Otsuki, N. Ueda & J. Takahara 511

Diagnostic value of ferritin, haptoglobin, a,-antitrypsin, lactate dehydrogenase and complement factors C3 and C4 in pleural

effusion differentiation

M. Alexandrakis, S. Coulocheri, D. Kyriakou, D. Bouros, N. Xirouhaki, N. Siafakas, E. Castanas & G. D. Eliopoulos

Attendance at an asthma educational intervention: characteristics of participants and non-participants

0. Abdulwadud, M. Abramson, A. Forbes, A. James, L. Light, F. Thien & E. H. Walters

A new bronchoscopic technique for the diagnosis of bacterial pneumonia in HIV-positive patients

J. Sauleda, A. Maim& M. Riera, J. Ramirez, B. Togores, S. Pons, A. Payeras & A. G. N. Agusti 530

Partial pulmonary sympathetic denervation by thoracoscopic D2-D3 sympathicolysis for essential hyperhidrosis: effect on the

pulmonary diffusion capacity

M. M. P. Noppen & W. G. Vincken 537 ~~~~~~~,~~~~~~,~, mmmmlmm41 ~~“il,~~j~~rp~‘~~~~~~~~,~~~~~~~~~~.n~~~~~~,~~~~“~~ arrn$b, n~~,~.~~,“~~~“~~~~~

Tuberculosis in health service employees in Northern Ireland

M. Riley, C. M. Loughr P. Wilkinson, C. C. Patterson & G. Varghese 546 ~~~“~Qxn~iill~a~~~~~~,~~,~

Impairment of muscle energy metabolism in patients with sleep apnoea syndrome

adier, C. Guillot, S. Delpierre, hjah & P.

f circulating KL-6, type III procollagen N-terminal peptide and type IV collagen IS in patients with

interstitial pneumonitis and alveolar pneumonia

N. Kohno, A. Yokoyam , Y. Hirasawa, K. Kondo, S. F .. 556 Tia~~~~~“mc~~~sBB,; R~iilsPhllWIC~~mlri~~~

Case Reports Left atria1 tumour mimicking pulmonary embolism

E. C. Seal, H. R. Rutter, M. C. Horrigan & M. G. Britton SjPIpbill

562

Chemotherapy-induced myocardial necrosis in a patient with chronic lymphocytic leukemia

D. G. Federman & G. Henry

Primary biphasic synovial sarcoma of the pleura

565

D. A. Jawahar, J. C. Vuletin, P. Gorecki, F. Persechino, M. Macera & P. Magazeh

Non-Hodgkin’s lymphoma presenting as Pancoast’s syndrome

S. M. Arcasoy, M. K. Bajwa & J. R. Jett

566

571

Number 10 November 1997

Editorials The implementation of asthma guidelines in general practice

M. R. Partridge

Organized care in general practice: structure and evaluation

cT!!mm1^5

Topical Reviews

576

Monitoring of bronchial asthma

R. Dahl, L. C. Martinati & A. L. Boner 581

Subject Index

Editorials, Letters to the Editor, Case Reports and Short Reports are k&&ed by (E), (L), (CR) and

(SR) after the page numbers, respectively.

A&E data retrieval 61-66 ACE levels

in metastatic ovarian dysgerminoma 237-9 (CR) non-correlation with radiographic staging of sarcoidosis

399-401 N-acetylcysteine as antioxidant enhancer 159-68 adenocarcinoma see under pulmonary adenoid cystic carcinoma metastasis manifested by pleural

effusion 169-70 (CR) airway

challenge test, lung auscultation in 151-7 inflammation following ozone exposures 47-55 inflammatory changes in asthmatic patients 323-6 obstructive syndrome, inflammatory pseudotumour of

lung presenting as 3814 (CR) stenosis after trachea-bronchial tuberculosis 107-10 (CR)

alveolar haemorrhage revealing epitheloid haemangioendo-

thelioma 111-14 (CR) pneumonia, KG6, type III procollagen N-terminal pep-

tide and type IV collagen 7s in 558- 61 volume effect on single breath DLCO interpretation

263-73 aminophylline effects on spirometry and exercise tolerance

in COPD 327-34 anaesthesia in ICU, propofol for 505-10 angiotensin II effect on bronchoconstriction 609-l 5 antibiotic use in acute lower RTI in general practice in UK

427-34 antioxidant enhancement by nacystelyn and N-

acetylcysteine 159-68 a,-antitrypsin deficiency

BMI and-mortality in subjects with 77-82 diagnostic value in pleural effusion differentiation 517-23 -induced emphysema, glucocorticosteroid inhalation

effect 275-9 asbestos exposure causing pleural mesothelioma and pul-

monary adenocarcinoma, use of MOC,, to distinguish 57-60 (CR)

aspergillosis allergic bronchopulmonary, CT scans 213-19 cerebromeningeal involvement after i.v. corticosteroid

therapy in asthma 435-7 (CR) asthma

&-agonists use 587-91 brittle, low IgG subclass levels in 464-9 care in GP 578-80 cerebromeningeal involvement in aspergillosis after i.v.

corticosteroid therapy 435-7 (CR) education intervention, attendance 524-9 effect of inspiratory capacity on bronchodilatation via

Turbohale@ or pressurized metered-dose inhaler 341-6

guidelines in GP 575-7 (E) hospitalization in island population 411-16 inflammatory changes in airways 323-6

monitoring, bronchial 581-6 morbidity reduction in community, asthma clinic and

63440 pathogenesis Al-A46 prevalence in Athens 83-88 social deprivation and 603-8 statistics in Netherlands 1980-84 417-22 steroid hypersensitivity 23 l-3 (SR) suspected, value of cold air hyperventilation in 470-8 symptom deterioration from isoniazid prophylaxis

438-40 (CR) related attendances data in A&E, retrieval method 61-66 self-reported, prevalence in Ankara 461-3 symptomatic 121-34

atria1 tumour, left, mimicking pulmonary embolism 562-3 (CR)

basement membrane thickness in bronchial epithelial cells in lung disease 406-10

&agonists use 587-91 blood lymphocyte cell subsets in COPD associated with

smoking, IgE and lung function 67-76 body mass index and mortality in subjects with severe

a,-antitrypsin deficiency 77-82 Book Reviews

Airway smooth muscle: modelling the asthmatic response in vivo 179

Prehospital emergency care: a guide to paramedics 3rd edn 441

breast cancer radiotherapy, bronchiolitis obliterans organ- izing pneumonia following 241- 4 (CR)

bronchial epithelial cells in lung disease, thickness of basement

membrane 406-l 0 hyper-responsiveness loss following ozone exposures

47-55 hyper-responsiveness, symptomatic 121-34 tone, lack of inhibition by nitric oxide 33540

bronchiectasis in Finland, hospital treatment 395-8 bronchiolitis obliterans

in HIV infection 171-3 (CR) organizing pneumonia after radiotherapy for breast

cancer 2414 (CR) steroid-resistant, cyclophosphamide in 175-7 (CR)

bronchitis, chronic, symptoms related to snoring and sleep apnoea 5-12

bronchoalveolar lavage fluid from HIV-infected patients with bacterial pneumonia, interleukin-8 and leuko- triene B, in 317-21

bronchoconstriction angiotensin II effect 609-15 methacholine-induced, lack of inhibition by nitric oxide

33540 bronchodilatation via Turbohalerm or pressurized metered-

dose inhaler, effect of inspiratory capacity in asthma 341-6

INDEX

bronchogenic carcinoma, comparison of cytokeratin frag- ment 19, tissue polypeptide antigen and carcinoembry- onic antigen as markers 13542

bronchopulmonary aspergillosis, allergic, CT scans 213-19 bronchoscopic technique for diagnosis of bacterial pneu-

monia in HIV-positive patients 530-6 bronchoscopy, rapidly expanding tuberculous lung cavity

following 377-9 (CR) Burkholderia (Pseudomonas) cepacia isolates genetic relat-

edness from cystic fibrosis centers 485-92

carbon monoxide diffusing capacity in whole lung, single- breath, effect of alveolar volume 263-73

carcinoembryonic antigen as tumour marker in broncho- genie carcinoma 13542

cerebromeningeal involvement in aspergillosis after i.v. corticosteroid therapy in asthma 435-7 (CR)

chest X-ray results in pulmonary TB diagnosis in low- incidence country 28 1-5

chronic obstructive pulmonary disease effects of ipratropium bromide and aminophylline on

spirometry and exercise tolerance 327-34 hypoxic, adequacy of oxygenation in long-term domicili-

ary oxygen therapy 287-9 1,442 ventilatory response to positive and negative work in

143-9 chylothorax in liver cirrhosis 118-19 (L) cirrhosis see under liver coal miners, single-breath nitrogen test 479984 coal-dust exposure, lactate dehydrogenase and isoenzyme

pattern in ex-coalminers 616-23 collagen 7S, type IV, in interstitial pneumonitis and

alveolar pneumonia 558-61 complement

consumption in post-traumatic pleural effusion 373-5 (CR)

factors C3 and C4 diagnostic value in pleural effusion differentiation 5 17-23

coronary artery bypass surgery, pulmonary function fol- lowing 629-33

corticosteroid comparisons in chronic sarcoidosis 449960 inhalation use for asthma in island population 41 l-l 6 therapy in asthma, cerebromeningeal involvement in

aspergillosis after 435-7 (CR) cyclophosphamide in severe steroid-resistant bronchiolitis

obliterans organizing pneumonia 175-7 (CR) cystic fibrosis

centers, Burkholderia (Pseudomonas) cepacia isolates genetic relatedness 485-92

relationship between dyspnoea, pulmonary function and exercise capacity 4146

cytokeratin fragment 19 as tumour marker in bronchogenic carcinoma 13542

data retrieval on A&E data 61-66 deflazacort vs prednisone in chronic sarcoidosis 449-60 diffuse interstitial lung disease, alveolar volume effect on

single breath DLCO interpretation 263-73 dyspnoea relationship with pulmonary function and exer-

cise capacity in cystic fibrosis 4146

emphysema alveolar volume effect on single breath DLCO interpret-

ation 263373

from a,-antitrypsin deficiency, glucocorticosteroid inha- lation effect 275-9

endobronchial metastasis from rectal adenocarcinoma 245-8 (CR)

eosinophilic cationic protein, seasonal variation in general population 347-9

exercise capacity relationship with dyspnoea and pulmonary

function in cystic fibrosis 4146 tests, ventilatory response in COPD 143-9 tolerance, effects of ipratropium bromide and amino-

phylline in COPD 327-34

ferritin diagnostic value in pleural effusion differentiation 517-23

Filgrastim safety trial in severe community acquired pneu- monia 387-94

forced expiratory flow reduction in children with respira- tory symptoms 443-8

foreign body inhalation, overlooked 293-6

gemcitabine clinical trial in advanced non-small cell lung cancer 42336

glucocorticosteroid inhalation effect in emphysema from a,-antitrypsin deficiency 275-9

haemangioendothelioma, epitheloid, alveolar haemorrhage revealing 111-14 (CR)

halothane administration during liquid ventilation 255-62 causing pulmonary microvascular injury 351-60

haptoglobin diagnostic value in pleural effusion differentia- tion 517-23

hard metal lung disease and pneumothorax 103-5 (CR) head injury, pneumonia and 193-9 hepatocyte growth factor in idiopathic pulmonary fibrosis

511-16 histamine-induced bronchoconstriction, angiotensin II

effect 609-l 5 HIV infection

bronchiolitis obliterans in 171-3 (CR) bronchoscopic technique for diagnosis of bacterial pneu-

monia in 530-6 interleukin-8 and leukotriene B, in BAL fluid from

HIV-infected patients with bacterial pneumonia 317-21

smoking and clinical status effects on lung function 221-9 human alveolar macrophages, thalidomide effect on TNF-a

production by 31-39 hyperhidrosis, essential, partial sympathetic denervation

by thoracoscopic D2-D3 sympathociolysis, effect on pulmonary diffusion capacity 53745

hyperventilation, cold air, value in suspected asthma 470-8

IgE, blood lymphocyte cell subsets in COPD associated with 67-76

IgG subclass low levels in brittle asthma 4649 immunodeficiency in non-tuberculous mycobacterial dis-

ease 95-101 immunotherapy for TB control 14(E), 13-19 inflammatory pseudotumour of lung, presenting as airway

obstructive syndrome 3814 (CR) inhalers

metered-dose bronchodilatation, effect of inspiratory capacity in asthma 341-6

SpacehalerTM evaluation for salbutamol delivery 311-16

inspiratory capacity in asthma, effect on bronchodilatation via

Turbohale@ or pressurized metered-dose inhaler 341-6

flow effects on Turbuhaler aerosol particle size distri- bution 624-8

intensive care unit, sedation with propofol 505-10 interleukin-8 in BAL fluid from HIV-infected patients with

bacterial pneumonia 3 17-2 1 interstitial pneumonitis, KL-6, type III procollagen

N-terminal peptide and type IV collagen 7s in 558861 intubation, tracheobronchopathia osteochondroplastica

presenting at 496-8 (CR) ipratropium bromide effects on spirometry and exercise

tolerance in COPD 327-34 isoflurane causing pulmonary microvascular injury 351-60 isoniazid prophylaxis causing deterioration in asthma

symptoms 43840 (CR)

Kikuchi’s disease and SLE 117-18 (L) KL-6 levels in interstitial pneumonitis and alveolar pneu-

monia 558861

lactate dehydrogenase diagnostic value in pleural effusion differentiation 517-23 and isoenzyme pattern in ex-coalminers 616-23

large cell lung cancer presenting with numb chin syndrome 235-6 (CR)

leukaemia, chronic lymphocytic, chemotherapy-induced myocardial necrosis 564-6 (CR)

leukotriene B, in BAL fluid from HIV-infected patients with bacterial pneumonia 3 17-2 1

liquid ventilation, halothane administration during 255-62 liver cirrhosis, chylothorax in 118-19 (L) lung

aspirates, diagnoses of pneumococcal antigen by PCR vs culture 20 l-6

auscultation in airway challenge test 15 l-7 cancer, large cell, presenting with numb chin syndrome

235-6 (CR) non-small cell, gemcitabine clinical trial 423-6 non-small cell, response to chemotherapy analysed by

three tumour markers 361-7 cavity expansion, tuberculous, following bronchoscopy

377-9 (CR) disease from hard metal 103-5 (CR)

mild-moderate, ‘Quality-of-Life for Respiratory Illness Questionnaire 297-309

thalidomide effect on tumour necrosis-a production 31-39

thickness of basement membrane in bronchial epithe- lial cells 406-10

function, blood lymphocyte cell subsets in COPD associ- ated with 67-76

function, effects of smoking and clinical status in HIV infection 221-9

inflammatory pseudotumour presenting as airway obstructive syndrome 3814 (CR)

mechanical ventilation, tracheal strictures following 5034 (CR)

mesothelioma see under pleural 57-60 (CR) methacholine-induced bronchoconstriction, lack of inhi-

bition by nitric oxide 33540

MOC,, in asbestos sprayer too distinguish between pleural mesothelioma and pulmonary adenocarcinoma 57-60 (CR)

mortality related to BMI in subjects with severe a,-antitrypsin deficiency 77-82

muscle energy metabolism impairment in sleep apnoea syndrome 55 l-7

mycobacterial disease, non-tuberculous, immunodeficiency in 95101

Mycobacterium tuberculosis culture results in low-incidence TB country 281-5

Mycobacterium vaccae immunotherapy for tuberculosis 13-19

myocardial necrosis, chemotherapy-induced in chronic lym- phocytic leukaemia 564-6 (CR)

nacystelyn as antioxidant enhancer 159-68 neutrophil elastase in idiopathic pulmonary fibrosis 511-16 nitric oxide lack of inhibition on bronchial tone and

methacholine-induced bronchoconstriction 33540 nitrogen test, single-breath, in coal miners 479-84 non-Hodgkin’s lymphoma presenting as Pancoast’s syn-

drome 570-l (CR) numb chin syndrome in metastatic large cell lung cancer

235-6 (CR) \ , nurse-run asthma clinic effect on asthma morbidity in

community 63440 nutritional support in advanced pulmonary disease 249-54

obstructive sleep apnoea in chronic bronchitis, symptoms related to 5-12 diagnosis and treatment 1X1-91,442 muscle energy metabolism impairment in 551-7

ovarian dysgerminoma, metastatic, ACE levels in 237-9 (CR)

oxygen therapy importance of process variables in long-term assessment

89-93 long-term, quality of life for patients 592-602

oxygenation adequacy in patients with hypoxic COPD treated with long-term domiciliary oxygen 287-91,442

ozone exposures, airway inflammation following 47-55

Pancoast’s syndrome, non-Hodgkin’s lymphoma presenting as 570-l (CR)

PCR for diagnosis of pneumococcal antigen in lung aspir- ates 201-6

perfluorochemical liquid ventilation, halothane admin- istration during 255--62

pleural effusion as sign of salivary adenoid cystic carcinoma

metastasis 169970 (CR) diagnostic criteria 5 17-23 post-traumatic, local complement consumption 373-5

(CR) mesothelioma distinguished from pulmonary adenocarci-

noma using MOC,, in asbestos sprayer 57760 (CR) primary biphasic synovial sarcoma 567-9 (CR)

pneumococcal antigen detection in lung aspirates by PCR technique vs culture 201-6

pneumonia aetiology following isolated closed head injury 193-9 bacterial, bronchoscopic technique for diagnosis in HIV-

positive patients 530-6 interleukin-8 and leukotriene B, in BAL fluid from

HIV-infected patients with 3 17-21

hDEX

KL-6, type III procollagen N-terminal peptide and type IV collagen 7s in 558-61

severe community acquired, Filgrastim safety trial in 387-94

see also specijic types e.g. varicella pneumonia pneumothorax from hard metal lung disease 103-5 (CR) prednisone vs deflazacort in chronic sarcoidosis 449-60 procollagen N-terminal peptide, type III, in interstitial

pneumonitis and alveolar pneumonia 558-61 propofol for sedation in ICU 505510 pulmonary

adenocarcinoma distinguished from pleural mesotheli- oma using MOC,, in asbestos sprayer

aspergillosis with cerebromeningeal involvement after iv. corticosteroid therapy in asthma 43557 (CR)

disease, advanced, nutritional support 249-54 TB immunotherapy 13-29

fibrosis, idiopathic, hepatocyte growth factor and neu- trophil elastase in 511-16

function after coronary artery bypass surgery 629-33 relationship with dyspnoea and exercise capacity in

cystic fibrosis 41-46 microvascular injury following halothane and isoflurane

351-60 nodules in pyoderma gangrenosum 493-5 (CR)

pyoderma gangrenosum, pulmonary nodules in 493-5 (CR)

quality of life in patients on long-term oxygen therapy 592-602

Quality-of-Life for Respiratory Illness Questionnaire 2977 309

rectal adenocarcinoma, endobronchial metastasis from 245-8 (CR)

respiratory infection, asthma exacerbation in, low IgG subclass levels

in 464-9 symptoms, self-reported, prevalence in Ankara 461-3 tract infection, lower, current antibiotic use in general

practice in UK 427-33

salbutamol delivery, comparisons of inhalers 3 1 l-15 salivary adenoid cystic carcinoma metastasis manifested by

pleural effusion 169970 (CR) sarcoidosis,

ACE levels non-correlation with radiographic staging of 399401

chronic, corticosteroid comparisons in 449-60 sarcoma, primary biphasic synovial, of pleura 567-9 (CR) seasonal variation in serum eosinophilic cationic protein in

general population 347-9 serum eosinophilic cationic protein, seasonal variation in

general population 347-9 single breath DLCO interpretation, alveolar volume effect

263-73

sleep apnoea see obstructive sleep apnoea smoking

blood lymphocyte cell subsets in COPD associated with 67-76

effects on lung function in HIV infection 221-9 snoring in chronic bronchitis, symptoms related to 5-12 social deprivation and asthma 603-S SpacehalerTM evaluation for salbutamol delivery 3 1 l-l 6 spirometer, pocket-sized turbine, use in children 369-72

0-N spirometry, effects of ipratropium bromide and aminophyl-

line in COPD 327-34 steroid hypersensitivity in asthma 231-3 (SR) sympathociolysis, thoracoscopic, for essential hyperhidrosis

53745 systemic lupus erythematosus, Kikuchi’s disease and

117-18 (L)

thalidomide effect on TNF-a production by human alveolar macrophages 31-39

thoracoscopic sympathicolysis for essential hyperhidrosis 537-45

tissue polypeptide antigen as tumour marker in broncho- genie carcinoma 13542

tracheal strictures following mechanical ventilation 503-4 (CR)

tracheobronchial tuberculosis, airway stenosis after 107-10 (CR)

tracheobronchopathia osteochondroplastica 499-502 (CR) presenting at difficult intubation 496-8

tuberculosis in health service employees in N. Ireland 546-50 immunotherapy 14 (E), 13-19 pulmonary, diagnostic strategy 281-5 tracheobronchial, airway stenosis after 107-10 (CR)

tuberculous lung cavity expansion after bronchoscopy 377-9 (CR)

tumor necrosis factor-a production by human alveolar macrophages, thalidomide effect 31-39

tumour marker analysis of response chemotherapy in non- small lung cancer 361-7

Turbohale? bronchodilatation effect of inspiratory ca- pacity in asthma 341-6

Turbuhaler aerosol particle size distribution, inspiratory flow effects 624-8

varicella pneumonia management 207-l 3 ventilation, liquid, halothane administration during 255-62 ventilatory response to positive and negative work in

patients with COPD 143-9 VolumaticTM evaluation for salbutamol delivery 31 l-l 6

wheezing, self-reported, prevalence in Ankara 461-3

INDEX

Author Index

Aalderen WMC van see De Jong W Abba AA. Kikuchi’s disease and SLE 117-18 (L) Abdulwadud 0, Abramson M, Forbes A, James A, Light

L, Thien F, Walters EH. Attendance at an asthma educational intervention: characteristics of partici- pants and non-participants 524-9

Abe M see Kohno N Aboussouan LS, Golish JA, Dinner DS, Strome M,

Mendelson WB. Limitations and promise in the diagnosis and treatment of obstructive sleep apnoea 181-91,442

Abramson M see Abdulwadud 0 Adaliogli G see Saraclar Y Agusti AGN see Sauleda J Akcabay M see Gunaydin B Al-Haijaj MS see Al-Majed SA Al-Kattan K see Al-Majed SA Al-Majed SA, Ashour M, Al-Mobeireek AF, Al-Haijaj MS,

Alzeer AH, Al-Kattan K. Overlooked inhaled foreign bodies: late sequelae and the likelihood of recovery 293- 6

Al-Mobeireek AF see Al-Majed SA Alexandrakis M, Coulocheri S, Kyriakou D, Bouros D,

Xirouhaki N, Siafakas N, Castanas E, Eliopoulos GD. Diagnostic value of ferritin, haptoglobin, a,- antitrypsin, lactate dehydrogeanse and complement factors C3 and C4 in pleural effusion differentiation 517-23

Alzeer AH see Al-Majed SA Ameglio F see Paone G Andresen J see deBoisblanc BP App EM see Gillissen A Aquilini M see Mariotta S Arcasoy SM, Bajwa MK, Jett JR. Non-Hodgkin’s lym-

phoma presenting as Pancoast’s syndrome 570-l Arnold AG see Wahbi ZK Ashour M see Al-Majed SA Atkin A see Dickinson J Austin EJ see Premaratne UN Avarlis P see Papageorgiou N Aykut-Baturalip A see De Blay F Ayres JG, Thompson RA. Low IgG subclass levels in

brittle asthma and in patients with exacerbations of asthma associated with respiratory infection 464-9

Babacan A see Gunaydin B Badier M see Vanuxem D Bajwa MK see Arcasoy SM Balzan MV see Cacciottolo JM Barbieri V see Calderazzo M Baron J see McCabe RN Bear MB see deBoisblanc BP Belt-Gritter B van der see De Jong JW Benfield TL see Krarup E Berton C see Monlun E Bhagat R see Panchal N Bird AG see Froebel KS Bisetti A see Mariotta S

see Paone G Bjermer L, Larsson L. Long-acting &agonists: how are

they used in an optimal wawy? 587791 Bjiirsson E see Janson C

Bohadana A see Purohit A Bollart FGE see Froebel KS Boner AL see Dahl R Bonora S see Cazzadore A Borras JM see Granados A Bourgkard E, Teculsecu D, Caillier I, Marchand M,

Costantino E, Pham QT. The single- breath nitrogen test in coal miners: factors associated with failure to perform 479984

Bourke SJ see Purcell IF Bouros D see Alexandrakis M Bovyn G see Coetmeur D Bredin CP see Cotter TP Briens E, Caulet-Maugendre S, Desrues B, Quinquenel Ml,

Lena H, Turlin B, Delaval Ph. Alveolar haemorrhage revealing epitheloid haemangioendothelioma 111-14 (CR)

Britton MG see Seal EC Broholm H see Meyer CN Buhagiar A see Cacciottolo JM Burney PG see Premaratne UN Burr ML, Verrall C, Kaur B. Social deprivation and

asthma 603-S

Cacciottolo JM, Balzan MV, Buhagiar A. Hospitalization of adults for asthma and inhaled corticsteroid use in an island population 41 l-16

Caillier 1 see Bourgkard E Calderazzo M, Gallilli A, Barbieri V, Roccia F, Pelaia G,

Tranfa CME, Cavaliere S, Zorzi F. Inflammatory pseudotumour of the lung presenting as an airway obstructive syndrome 3814 (CR)

Cantin AM see Gillissen A Carlsson C see Kimless-Garber DR Cash ME see Shivaram U Castanas E see Alexandrakis M Caulet-Maugendre S see Briens E Cavaliere S see Calderazzo M Cazzadore A, Di Perri G, Vento S, Bonora S, Fendt D,

Rossi M, Lanzafame M, Mirandola F, Concia E. Aetiology of pneumonia following isolated closed head injury 193-9

Cetinkaya F see Saraclar Y Chong I-W see Huang M-S Clayton RA see Ramsay SG Cobben NAM, Drent M, Schols AMWJ, Lamers RJS,

Wouters EFM, Van Diejen-Visser MP. Serum lactate dehydrogenase and its isoenzyme pattern in ex-coal miners 616- 23

Coetmeur D, Bovyn G, Leroux P, Niel-Duriez M. Tracheo- bronchopathia osteochondroplastica presenting at the time of a difficult intubation 496-8 (CR)

Coffiner M see Gillissen A Collazos J see Diaz F Comellas M see Torre W Concia E see Cazzadore A Corlan E, Marica C, Macavei C, Stanford JL, Stanford

CA. Immunotherapy with Mycobactevium vaccae in the treatment of tuberculosis in Romania. 1. Newly- diagnosed pulmonary disease 13-19; 2. Chronic or relapsed disease 21-29

Costantino E see Bourgkard E

INDEX

Cotter TP, Kealy NP, Duggan PF, Curtain A, Bredin CP. Elevated serum angiotensin converting enzyme levels in metastastic ovarian dysgerminoma 237-9 (CR)

Coulocheri S see Alexandrakis M Crimi E see Oddera S Cracker J see Ryan PJ Crompton GK see Gunawardena KA Cuesta M see Torre W Cukier A see Vargas FS Curtain A see Cotter TP

Dagg KD see Ramsay SG Dahl R, Martinati LC, Boner AL. Monitoring of bronchial

asthma 581-6 Davies CWH, Wathen CG. Kikuchi’s disease and SLE

117-18 (L) De Angelis G see Paone G De Blay F, Aykut-Baturalip A, Goetz J, Purohit A, Perez-

Infante A, Hauptmann G, Pauli G. Post-traumatic pleural effusion: demonstration of local complement consumption 373-5 (CR)

see also Monlun E deBoisblanc BP, Mason CM, Andresen J, Logan E, Bear

MB, Johnson S, Shellito J, Summer WR, Nelson S. Phase 1 safety tiral of Filgrastim (r-metHuG-CSF) in non-neutropenic patients with severe community- acquired pneumonia 387-94

De Jong JW, Belt-Gritter B van der, Koeter GH, Postma DS. Peripheral blood lymphocyte cell subsets in sub- jects with COPD: association with smoking, IgE and lung function 67-76

De Jong W, van der Schans CP, Mannes GPM, van Aalderen WMC, Grevink RG, Koeter GH. Relation- ship between dyspnoea, pulmonary function and exer- cise capacity in patients with cystic fibrosis 41-46

De Marchis L see Paone G Dekhuijzen PNR see Rooyackers JM Delaval Ph see Briens E Delpierre S see Vanuxem D Demirel Y see Saraclar Y Demoncheaux EAG see Maniscalo M Desrues B see Briens E Devadason SG see Everard ML Di Perri G see Cazzadore A Diaz F, Collazos J, Martinez E, Mayo J. Bronchiolitis

obliterans in a patient with HIV infection 171-3 (CR) Dickinson J, Hutton S, Atkin A, Jones K. Reducing asthma

morbidity in the community: the effect of a tergeted nurse-run asthma clinic in an English general practice 63450

Dietrich S see Kumar A Dilworth P see Tavares JL Dinner DS see Aboussouan LS Dirkman JH see Mail16 AR Dirksen A see Wilcke JTR Dossing M see Meyer CN Dousse N see Janssens J-P Drent M see Cobben NAM Duggan PF see Cotter TP Dun J, Fan Chung K. Airway inflammation despite loss of

bronchial hyper-responsniveness after multiple ozone exposures 47-55

Eliopoulos GD see Alexandrakis M Enander I see Janson C Escarrabill J see Granados A

Everard ML, Devadason SG, Le Souef PN. Flow early in the inspiratory manoeuvre affects the aerosol particle size distribution from a Turbuhaler 624-8

Falfuera M see Ruiz-Gonzalez A Fan Chung K see Dun J Faraone S see Maniscalo M Faurschou P, Viskum K. Artifical pneumothorax by the

Veress cannula: efficacy and safety 402-5 Federam DG, Henry G. Chemotherapy-induced myocar-

dial necrosis in a patient with chronic lymphocytic leukaemia 5646 (CR)

Fendt D see Cazzadore A Flood-Page P see Partridge MR Folgering HTM see Rooyackers JM Forbes A see Abdulwadud 0 Foresti V, Villa A, Scolari N. Chylothorax in liver cirrhosis

118-19 (L) Frances C see Frans A Frans A, Nemery B, Veriter C, Lacquet L, Frances C.

Effect of alveolar volume on the interpretation of single breath ti~C0 263-73

Frey J see Janssens J-P Froebel KS, Bollart FGE, Jellema J, Bird AG, Greening

AP. Immunodeficiency in non-tuberculous mycobac- terial disease 95-101

Fujino S see Kohno N Fujita J see Hojo S

Gaga M see Papageorgiou N Gallilli A see Calderazzo M Galluccioo G see Paone G Gasser Bv Gillissen A, Jaworska M, Orth M, Coffiner M, Maes P,

App EM, Cantin AM; Schultze-Werninghaus G. Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro 159-68

Goetz J see De Blay F Golish JA see Aboussouan LS Gorecki P see Jawahar DA Granados A, Escarrabill J, Borras JM, Rodriguez-Roisin

R. The importance of process variables analysis in the assessment of long-term oxygen therapy by concentra- tor 89-93

Grange JM. Immunotherapy: a new strategy for tubercu- losis control 14(E)

Greco S see Paone G Greening AP see Froebel KS Grevink RG see De Jong W Griffin R see McCabe RN Guidi L see Mariotta S Guillot C see Vanuxem D Gunawardena KA, Sohal T, Jones JI, Upchurch FC,

Crompton GK. The SpacehalerTM for delivery of salbu- tamol: a comparison with the standard metered-dose inhaler plus VolumaticTM spacer device 3 11-16

Gunaydin B, Karadenizil Y, Babacan A, Kaya K, Unlu M, Inanir S, Mahli A, Akcabay M, Yardim S. Pulmonary microvascular injury following general anaesthesia with volatile anaesthetics - halothane and isoflurane: a comparative clinical and experimental study 35 l-60

Hakanson L see Janson C Halme M, Jekunen A, Tamminen K, Mattson K. Phase II

study of weekly gemcitabine in advanced non-small cell lung cancer 423-6

INDEX

Hammond JM see Potgieter PD Hansen HS see Mostgaard G Hauptmann G see De Blay F Henry G see Federam DG Higenbottam T see Maniscalo M Higgins B see Wilkinson SM Hirasawa Y see Kohno N Hirsch T, Peter-Kern M, Koch R, Leupold W. Influence

of inspiratory capacity on bronchodilatation via Turbohaler@ or pressurized metered-dose inhaler in asthmatic children: a comparison 341-6

Hiwada K see Kohno N Hojo S, Fujita J, Yoshinouchi T, Yamanouchi H, Kamel T,

Yamadori I, Otsuki Y, Udea N, Takahara J. Hepato- cyte growth factor and neurophil elsatase in idiopathic pulmonary fibrosis 511-16

Holmes W see Macfarlane J Holscher HC see Laar JM van Honicky R see Kumar A Horrigan MC see Seal EC Huang M-S, Jong S-B, Tsai M-S, Lin MS, Chong I-W, Lin

H-C, Hwang J-J. Comparison of cytokeratin fragment 19 (CYFRA 21-2) tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA) as tumour markers in bronchogenic carcinoma 135- 42

Hueb W see Vargas FS Huelin E see Ruiz-Gonzalez A Hutton S see Dickinson J Hwang J-J. see Huang M-S Hyldebrandt N see Mostgaard G

Ichinose Y see Kasugu I Imbimbo B see Rizzato G Inanir S see Gunaydin B

Jacobson R see Kumar A Jaeger A see Monlun E Jahhah F see Vanuxem D James A see Abdulwadud 0 Jansen DF, Timens W, Kraan J, Rijken B, Postmas DS.

Asymptomatic bronchial hyper-responsiveness and asthma 121-34

Janson C, Bjorsson E, Enander I, Hakanson L. Seasonal variation in serum eosinophilic cationic protein (S-ECP) in a general popoulation sample 347-9

Janssens J-P, Rochat T, Frey J-G, Dousse N, Pichard C, Tschopp J-M. Health-related quality of life in patients under long-term oxygen therapy: a home-based descriptive study 592-602

Jawahar DA, Vuletin JC, Gorecki P, Persechino F, Macera M, Magazeh P. Primary biphasic synovial sarcoma of the pleura 567-9 (CR)

Jaworska M see Gillissen A Jefery GM see Lee YC Jekunen A see Halme M Jellema J see Froebel KS Jett JR see Arcasoy SM Johnson S see deBoisblanc BP Jones B see Tsang KWT Jones JI see Gunawardena KA Jones K see Dickinson J Jong S-B see Huang M-S Jonsson A-C see Larsson L-G Jonsson E see Larsson L-G

Kalayci a see Saraclar Y Kamel T see Hojo S Kaptein AA see MaillC AR Karadenizil Y see Gunaydin B Kasugu I, Yanagisawa N, Takkeo C, Koga M, Kiyokawa

H, Yonemaru M, Ichinose Y, Toyama K. Multiple pulmonary nodules in association with pyoderma gangrenosum 493-5 (CR)

Kaur B see Burr ML Kaya K see Gunaydin B Kealy NP see Cotter TP Keistinen T see Saynajakangas 0 Kimless-Garber DR, Wolfson MR, Carlsson C, Shaffer

TH. Halothane administration during liquid ventila- tion 255-62

Kivela S-L see Saynajakangas 0 Kiyokawa H see Kasugu I Koch R see Hirsch T Ko&ter GH see De Jong W Koga M see Kasugu I Kohno N, Yorokama A, Hirasawa Y, Kondo K, Fujino S,

Abe M, Hiwada K. Comparative studies of circulating KL-6, type III procollagen N-terminal peptide and type IV collagen 7s in patients with interstitial pneu- monitis and alveolar pneumonia 558-61

Kok-Jensen A see Wilcke A Kondo K see Kohno N Koning CJM see Mail16 AR Kopferschmitt-Kubler MC see Purohit A Koskela HO, RPsHnen SH, Tukiainen HO. The diagnostic

value of cold air hyerventilation in adults with sus- pected asthma 470-8

Kotecha S see Tavares JL Kraan J see Jansen DF Krarup E, Vestbo J, Benfield TL, Lundgren JD.

Interleukin-8 and leukotriene B, in bronchoalveolar lavage fluid from HIV-infected patients with bacterial pneumonia 3 17- 21

Krieken JHJM van see Laar JM van Kumar A, Dietrich S, Schneider W, Jacobson R, Pouch

Downes F, Robinson-Dunn BE, Honicky R, Smith J, Martin R. Genetic relatedness of Burkhoideriu (Pseudomonas) cepacia isolates from five cystic fibrosis centers in Michigan 485-92

Kyriakou D see Alexandrakis M Kyriakou M see Papageorgiou N

Laar JM van, Holscher HC, Krieken JHJM van, Stolk J. Bronchiolitis obliterans organizing pneumonia after adjuvant radiotherapy for breast carcinoma 241-4 (CR)

Lacquet L see Frans A Lamers RJS see Cobben NAM Lanzafame M see Cazzadore A Larsson L see Bjermer L Larsson L-G, Lundback B, Jonsson A-C, Lindstrom M,

Jonsson E. Symptoms related to snoring and sleep apnoea in subjects with chronic bronchitis: report from the Obstructive Lung Disease in Northern Sweden Study 5-12

Le So&f PN see Everard ML Lee YC, Wong CS, Jefery GM. Endobronchial metastasis

from rectal adenocarcinoma 245-8 (CR) Lena H see Briens E Leroux P see Coetmeur D Leupold W see Hirsch T

INDEX

Levy ML. Organize care in general practice: structure and evaluation 578-80

Lewis SA see Macfarlane J Light L see Abdulwadud 0 Light RW see Vargas FS Lin H-C see Huang M-S Lin M-S see Huang M-S Linder J see Purohit A Lindstriim M see Larsson L-G Logan E see deBoisblanc BP Loughrey CM see Riley M Lundback B see Larsson L-G Lundgren JD see Krarup E

Macavei C see Corlan E Macera M see Jawahar DA Macfarlane J, Lewis SA, Macfarlane R, Holmes W. Con-

temporary use of antibiotics in 1089 adults presenting with acute lower respiratory tract illness in general practice in the U.K.: implications for developing man- agement guidelines 427-34

Macfarlane R see Macfarlane J MacNee W see Morrison D Maes P see Gillissen A Magazeh P see Jawahar DA Mahli A see Gunaydin B Mahr L see Purohit A Maille AR, Koning CJM, Zwinderman AH, Willems LNA,

Dirkman JH, Kaptein AA. The development of the ‘Quality-of-Life for Respiratory Illness Questionnaire (QQL-RIQ)‘: a disease-specific quality-of-life question- naire for patients with mild to moderate chronic non- specific lung disease 297-309

Maim6 A see Sauleda J Maniscalco M, Sofia M, Smith A, Demoncheaux EAG,

Mormile M, Faraone S, Higenbottam T. Lack of effect of nitric oxide inhibition on bronchial tone and methacholine-induced bronchoconstriction in man 33540

Mannes GPM see De Jong W Marchand M see Bourgkard E Marica C see Corlan E Marinella MA. Metastatic large cell cancer presenting with

numb chin syndrome 235-6 (CR) Propofol for sedation in the intensive care unit: essentials

for the clinician 505-10 Mariotta S, Guidi L, Aquilini M, Tonnarini R, Bisetti A.

Airway stenosis after trachea-bronchial tuberuclosis 107-lO(CR)

Marks GB see Premaratne UN Marossis C see Papageorgiou N Marshall B see Tavares JL Marshall SM see Purcell IF Martin R see Kumar A Martinati LC see Dahl R Martinez E see Diaz F Mason CM see deBoisblanc BP Mateo F see Shivaram U Mattey DL see Wilkinson SM Mattson K see Halme M Mayo J see Diaz F McCabe RN, Baron J, Griffin R, Omogbehin M, Snashall

PD, Seed WA. Effects of smoking and clinical status on lung function in human immunodeficiency virus- seropositive subjects 221-9

Mendelson WB see Aboussouan LS

Meyer CN, Dossing M, Broholm H. Tracheobroncho- pathia osteochondroplastica 499- 502 (CR)

Milani S see Rizzato G Mirandola F see Cazzadore A Misirhgil Z see Saraclar Y Monlun E, De Blay F, Berton C, Gasser B, Jaeger A, Pauli

G. Invasive pulmonary aspergillosis with cerebro- meningeal involvement after short-term intravenous corticosteroid therapy in a patient with asthma 435-7 (CR)

Mormile M see Maniscalo M Morrison D, Skwarski KM, MacNee W. The adequacy of

oxygenation with hypoxic chronic obstructive pulmo- nary disease treated with long-term domiciliary oxygen 287- 91,442

Mostgaard G, Siersted HC, Hansen HS, Hyldebrandt N, Oxho H. Reduced forced expiratory flow in schoolchil- dren with respiratory symptoms: the Odense School- child Study 443-8

Mungall IPF see Tsang KWT

Nally JE see Ramsay SG Nelson S see deBoisblanc BP Nemery B see Frans A Newman Taylor AJ see Wahbi ZK Niel-Duriez M see Coetmeur D Nogues A see Ruiz-Gonzalez A Noppen MMP, Vincken WG. Partial pulmonary sympa-

thetic denervationo by thoracoscopic D2-D3 sym- pathicolysis for essential hyerhydrosis: effect on the pulmonary dissusion capacity 53745

Oates JL see Ryan PJ Oddera S, Silvestri M, Sacco 0, Crimi E, Rossi GA.

Inflammatory changes in proximal and peripheral air- ways of asthmatic patients 323-7

Omogbehin M see McCabe RN Orth M see Gillissen A Otsuki Y see Hojo S Owen S see Wilkinson SM Oxho H see Mostgaard G

Panchal N, Bhagat R, Pant C, Shah A. Allergic broncho- pulmonary aspergillosis: the spectrum of computed tomography appearances 213-19

Pant C see Panchal N Paone G, De Angelis G, Greco S, Portalone L, De Marchis

L, Galluccioo G, Taglienti A, Bisetti A, Ameglio F. Evaluation of response to chemotherapy in patients affected with non-small cell lung cancer by means of three tumour markers elaborated by discriminant analysis 361-7

Papageorgiou N, Gaga M, Marossis C, Reppas Chr, Avarlis P, Kyriakou M, Tsipra S, Zeibecogliou K, Tracopoulos G. Prevalence of asthma and asthma-like symptoms in Athens, Greece 83-86

Parker JM see Shorr AF Partridge MR. The implementation of astham guidelines in

general pratice 575-7 (E) Flood-Page P. Multiple tracheal strictures following

mechanical ventilation 50334 Patterson CC see Riley M Paul KP, Schultz T. Evaluation of a pocket-sized turbine

spirometer for clinical use with children 369-72

Pauli G see De Blay F see Monlun E see Purohit A

Payeras A see Sauleda J Pelaia G see Calderazzo M Perez-Infante A see De Blay F Persechino F see Jawahar DA Peter-Kern M see Hirsch T Pham QT see Bourgkard E Pichard C see Janssens J-P Polosa R, Colombrita R, Prosperini G, Cacciola R. A case

of acute deterioration in asthma symptoms induced by isoniazid prophylaxis 438-40 (CR)

Pons S see Sauleda J Parcel JM see Ruiz-Gonzalez A Portalone L see Paone G Postma DS see De Jong JW

see Jansen DF Potgieter PD, Hammond JM. Intensive care management

of varicella pneumonia 207-12 Pouch Downes F see Kumar A Premaratne UN, Marks GB, Austin EJ, Burney PG. A

reliable method to retrieve Accident and Emergency data stored on a free-text basis 61-66

Purcell IF, Bourke SJ, Marshall SM. Cyclophosphamide in severe steroid-resistance bronchiolitis obliterans organ- izing pneumonia 175-7

Purohit A, Bohadana A, Kopferschmitt-Kubler MC, Mahr L, Linder J, Pauli G

see also De Blay F

Quinquenel Ml see Briens E

Ramirez J see Sauleda J Ramsay SG, Clayton RA, Dagg KD, Thomson LJ, Nally

JE, Thomson NC. Effect of angiotensin II on histamine-indeed bronchoconstriction in the human airway both in vitro and in vivo 609-15

Rbanen SH see Koskela HO Reppas Chr see Papageorgiou N Riboldi A see Rizzato G Riera M see Sauleda J Rijken B see Jansen DF Riley M, Loughrey CM, Wilkinson P, Patterson CC,

Varghese G. Tuberculosis in health service employees in Northern Ireland 54650

Rizzato G, Riboldi A, Imbimbo B, Torresin A, Milani S. The long-term efficacy and safety of two different corticosteroids in chronic sarcoidosis 449-60

Robinson-Dunn BE see Kumar A Roccia F see Calderazzo M Rochat T see Janssens J-P Rodriguez-Roisin R see Granados A Rooyackers JM, Dekhuijzen PNR, van Herwaarden CLA,

Folgering HTM. Ventilatory response to positive and negative work in patients with chronic obstructive pulmonary disease 143-9

Rossi GA see Oddera S Rossi M see Cazzadore A Rubio-Caballero M see Ruiz-Gonzalez A Ruiz-Gonzalez A, Nogues A, Falfuera M, Parcel JM,

Huelin E, Rubio-Caballero M. Rapid detection of pneumococcal antigen in lung aspirates: comparison with culture and PCR technique 201-6

Rutter HR see Seal EC

Ryan PJ, Oates JL, Cracker J, Stableforth DE. Distinction between pleural mesothelioma and pulmonary adeno- carcinoma using MOC31 in an asebstos sprayer 57-60 (CR)

Sacco 0 see Oddera S SaraGlar Y, Cetinkaya F, Tuncer A, Kalayci 6, Adaliogli

G, Sekerel BE, Demirel Y, Misirhgil Z. The prevalence of self-reported asthma and respiratory symptoms in Ankara, Turkey 461-3

Sauleda J, Maim6 A, Riera M, Ramirez J, Togores B, Pons S, Payeras A, Agusti AGN. A new bronchoscopic technique for the diagnosis of bacterial pneumonia in HIV-positive patients 530-6

SayngjijBkangas 0, Keistinen T, Tuuponen T, KivelH S-L. Bronchiectasis in Finland: trends in hospital treatment 395-8

Schans CP van der see De Jong W Schneider W see Kumar A Schols AMWJ see Cobben NAM Schultz T see Paul KP Schultze-Werninghaus G see Gillissen A Scolari N see Foresti V Seal EC, Rutter HR, Horrigan MC, Britton MG. Left

atria1 tumour mimicking pulmonary embolism 562-3 (CR)

Seed WA see McCabe RN Seersholm N. Body mass index and mortality in patients

with severe a,-antitrypsin deficiency 77-82 Sekerel BE see SaraGlar Y Senju S see Watanabe K Shaffer TH see Kimless-Garber DR Shah A see Panchal N Shaw RJ see Tavares JL Shellito J see deBoisblanc BP Shim C see Shivaram U Shivaram U, Cash ME, Mateo F, Shim C. Effects of

high-dose ipratropium bromide and oral aminophyl- line on spirometry and exercise tolerance in COPD 3274

Shorr AF, Torrington KG, Parker JM. Serum angiotensin converting enzyme does not correlate with radio- graphic stage at initial diagnosis of sarcoidosis 399401

Siafakas N see Alexandrakis M Siersted HC see Mostgaard G Silvestri M see Oddera S Skwarski KM see Morrison D Smith A see Maniscalo M Smith J see Kumar A Snashall PD see McCabe RN Sofia M see Maniscalo M Sohal T see Gunawardena KA Stableforth DE see Ryan PJ Stanford CA see Corlan E Stanford JL see Corlan E Stolk J see Laar JM van Strome M see Aboussouan LS Summer WR see deBoisblanc BP

Taglienti A see Paone G Takahara J see Hojo S Takkeo C see Kasugu I Tamminen K see Halme M

INDEX

Tavares JL, Wangoo A, Dilworth P, Marshall B, Kotecha S, Shaw RJ. Thalidomide reduces tumour necrosis factor-a production by human alveolar macrophages 3 1-39

Teculsecu D see Bourgkard E Teixeira LR see Vargas FS Terra-Filho M see Vargas FS Thien F see Abdulwadud 0 Thompson RA see Ayres JG Thomsen C. Nutritional support in advanced pulmonary

disease 249-54 Thomson LJ see Ramsay SG Thomson NC see Ramsay SG Timens W see Jansen DF Togores B see Sauleda J Tonnarini R see Mariotta S Torre W, Comellas M, Cuesta M. Massive pleural effusion

as isolated manifestation of metastatic spread of sali- vary adenoid cystic carcinoma 169-70 (CR)

Torresin A see Rizzato G Torrington KG see Shorr AF Toyama K see Kasugu I Toyoshima H see Watanabe K Tracopoulos G see Papageorgiou N Tranfa CME see Calderazzo M Tsai M-S see Huang M-S Tsana KWT, Jones B, Mungall IPF. A case of rapidly

expanding tuberculous lung cavity after bronchoscopy 377-9 (CR)

Tschopp J-M see Janssens J-P Tsipra S see Papageorgiou N Tukiainen HO see Koskela HO Tuncer A see Saraclar Y Turlin B see Briens E Tuuponen T see Saynajakangas 0

Udea N see Hojo S Unlu M see Gunaydin B Upchurch FC see Gunawardena KA

Van Diejen-Visser MP see Cobben NAM van Herwaarden CLA see Rooyackers JM Vanuxem D, Badier M, Guillot C, Delpierre S, Jahhah F,

Vanuxem P. Impairment of muscle energy metabolism in patients with sleep apnoea syndrome 551-7

Vanuxem P see Vanuxem D Vargas FS, Terra-Filho M, Hueb W, Teixeira LR, Cukier

A, Light RW. Pulmonary function after coronary artery bypass surgery 629-33

Varghese G see Riley M Vento S see Cazzadore A

Veriter C see Frans A Verrall C see Burr ML Vestbo J see Krarup E Villa A see Foresti V Vincken WG see Noppen MMP Viskum K see Faurschou P Vuletin JC see Jawahar DA

Wahbi ZK, Arnold AG, Newman Taylor AJ. Hard metal lung disease and pneumothorax 103-5 (CR)

Walters EH see Abdulwadud 0 Wangoo A see Tavares JL Watanabe K, Senju S, Toyoshima H, Yoshida M. Thick-

ness of the basement membrane of bronchial epithelial cells in lung diseases as determined by transbronchial biopsy 40610

Wever AMJ see Wever-Hess J Wever-Hess J, Wever AMJ. Asthma statistics in the

Netherlands 1980-94 4 17-22 Wilcke A, Kok-Jensen A. Diagnostic strategy for pulmo-

nary tuberculosis in a low-incidence country: Results of chest X-ray and sputum cultured for Mycobacterium tuberculosis 281-5

Wilcke JTR, Dirksen A. The effect of inhaled glucocorti- coids in emphysema due to a,-antitrypsin deficiency 275-9

Wilkinson P see Riley M Wilkinson SM, Higgins B, Owen S, Mattey DL, Woodcock

A. An assessment of steroid hypersensitivity in asthma 231-3 (SR)

Willems LNA see Mail16 AR Wolfson MR see Kimless-Garber DR Wong CS see Lee YC Woodcock A see Wilkinson SM Wouters EFM see Cobben NAM

Xirouhaki N see Alexandrakis M

Yamadori I see Hojo S Yamanouchi H see Hojo S Yanagisawa N see Kasugu I Yardim S see Gunaydin B Yonemaru M see Kasugu I Yorokama A see Kohno N Yoshida M see Watanabe K Yoshinouchi T see Hojo S

Zeibecogliou K see Papageorgiou N Zorzi F see Calderazzo M Zwinderman AH see Maille AR 21