Report in Microbiology; Respiratory Sys

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    Disease Signs and

    Symptom

    s

    Pathogen/Ca

    usative

    Agent

    Reservoirs/

    Mode of

    Transmissio

    n

    Laborat

    ory

    Diagnos

    is

    Patient

    Care

    Acute

    Viral

    Rhinitis/

    AcuteCoryza

    (commo

    n cold)

    Coryza,

    sneezing,

    runny

    eyes, sorethroat,

    chills and

    malai

    Rhinoviruses,

    coronaviruses

    ,

    parainfluenzaviruses,

    respiratory

    syncytial

    virus (RSV),

    influenzaviruses,

    adenoviruses,

    enteroviruses

    Infected

    humans;tra

    nsmitted via

    respiratorysecretions

    by way of

    hands and

    fomites or

    directcontact with

    or

    inhalation

    of airbornedro lets

    Cell-

    culture

    techniq

    ue

    Use

    Droplet

    Precaution

    s forhospitalize

    d patients.

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    A representation of the molecular

    surface of one variant of

    human rhinovirus.

    http://en.wikipedia.org/wiki/Rhinovirushttp://en.wikipedia.org/wiki/Rhinovirus
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    Disease Signs

    and

    Symp-

    toms

    Pathogen/

    Causative

    Agent

    Reservoirs

    /Mode of

    Trans-

    mission

    Laboratory

    Diagnosis

    Patient

    Care

    Acute,

    Febrile,

    Viral

    Respirat

    ory

    Disease

    Chills,h

    eadach

    e,gener

    al

    aching,

    malaise

    ,

    anorexi

    a, GIdisturb

    ances

    parainfluen

    za viruses,

    respiratory

    syncytial

    virus (RSV),

    adenovirus,

    rhinoviruse

    s, certain

    coronaviruses,

    coxsackievir

    uses,echovi

    ruses

    Infected

    humans;tr

    ansmissio

    n direct

    oral

    contact or

    by

    droplet;in

    directlyvia

    fomites

    and fecal-

    oral route

    Isolation of

    the etiologic

    agent from

    respiratory

    secretions

    using cell

    cultures;imm

    unodiagnosti

    c andmolecular

    procedures

    available

    Use

    Standard

    Precautions

    for adult

    patients;

    add

    Ccontact

    Precautions

    for infantsand young

    children

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    Disease Signs and

    Symp-

    toms

    Pathogen

    /

    Causative

    Agent

    Reservoirs

    /Mode of

    Trans-

    mission

    Labora-

    tory

    Diagno-

    sis

    Patient

    Care

    Hantavirus

    Pulmonary

    Syndrome

    Fever,

    myalgias(

    muscular

    pain), GI

    complaints, cough,

    difficulty

    breathing,

    hypotension

    Hantaviru

    s(Sin

    Nombre,

    Bayou,

    BlackCreek

    Canal,

    New York-

    1,Mononga

    hela)

    rodents,;

    transmissio

    n is

    viainhalati

    on ofaerosolized

    rodent

    feces,

    urine, andsaliva

    Immuno

    diagnosti

    c and

    molecula

    rprocedur

    es and by

    cell

    culture

    Use

    Standard

    Precautions

    for

    hospitalizedpatients

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    Disease Signs and

    Symp-

    toms

    Pathogen

    /

    Causative

    Agent

    Reservoirs

    /Mode of

    Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Influenza

    (Flu)

    Fever,

    chills,

    headache

    s, pain

    throughout the

    body, sore

    throat,

    cough,nasal

    drainage;

    nausea

    and

    vomiting

    Influenza

    viruses

    types A,

    B,

    C;single-stranded

    RNA

    viruses in

    the familyOrthomyx

    oviruses

    Infected

    humans

    are

    primary

    reservoir;pigs and

    birds;

    transmissio

    n occursvia

    airborne

    spread and

    direct

    contact

    By

    isolation of

    influenza

    virusfrom

    pharyngealor nasal

    secretions

    or washing

    using cellstructure

    tech-

    niques

    Droplet

    Precau-

    tions

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    Disease Signs

    and

    Symp-

    toms

    Patho-

    gen/

    Causa-

    tive

    Agent

    Reservoirs/

    Mode of Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Avian

    In-

    fluenza

    (Birdflu)

    Fever,

    cough,

    sore

    throat,and

    muscle

    aches

    Avian In-

    fluenza

    virus

    type A:H5, H7,

    H9

    Infected wild and

    domesticated

    birds; bird-to-

    humantransmission

    occurs via contact

    with infected

    poultry or surfacesthat have been

    contaminated

    with excretions

    from infected

    birds

    Molecular

    diagnostic

    proce-

    dures orcell

    culture

    Use

    Droplet

    Precau-

    tions

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    Disease Signs and

    Symp-

    toms

    Patho-

    gen/

    Causativ

    e Agent

    Reservoirs/

    Mode of

    Transmission

    Labora-

    tory

    Diagno-

    sis

    Patient

    Care

    Severe

    Acute

    Respira-

    tory Syn-

    drome(SARS)

    High

    fever,

    chills,

    headache

    , ageneral

    feeling of

    discom-

    fort, bodyaches and

    some-

    times

    diarrhea

    SARS-

    associa-

    ted

    corona

    virus(SARS-

    CoV)

    Infected

    persons;trans

    mission

    occurs by

    respiratorydroplets or by

    touching the

    mouth, nose

    or eye aftertouching a

    contaminated

    surface or

    object

    Immuno

    diagnos-

    tic or

    molecu-

    lardiagnos-

    tic proce-

    dures or

    cellculture

    Use

    Standard,

    Airborne,

    Droplet,

    and ContactPrecautuio

    ns;use N95

    or higher

    respiratoryprotection

    and eye

    protection

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    h / b

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    Disease Signs and

    Symptoms

    Patho-

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Pneumo

    -nia

    Fever,

    productive

    cough,acut

    e chestpain, chills,

    shortness

    of breath

    Gram-

    positive or

    gram-

    negativebacteria,

    mycoplasm

    as,

    chlamydias, viruses,

    fungi,

    protozoa

    Infected

    humans,

    infected

    psittacinebirds, soil

    and bird

    droppings,

    transmission by

    droplet

    inhalation,

    direct oral

    contact

    Sputum

    specimen

    sent to

    themicrobiolo

    gy lab. For

    culture

    andsensistivit

    y (C&S)

    Use

    standard

    precuatio

    ns,Droplet

    and /or

    contact

    precautions

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    Di Si d P th R i / L b P ti t

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    Diseas

    e

    Signs and

    Symptoms

    Patho-

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Strepto

    coccal

    Pha-

    ryngitis

    (Strep

    throat)

    Soreness,

    chills, fever,

    headache, a

    beefy red

    throat, white

    patches of

    pus on

    pharyngial

    epitheliumenlarged

    tonsils,

    enlarged

    cervical

    lymph nodes

    Streptoco

    ccus

    pyogenes

    aka group

    A

    Streptoco

    ccus, GAS

    or Strep.

    A

    Infected

    humans,

    transmission

    via human-

    to-human

    direct

    contact,

    aerosol

    droplets,secretions

    from

    patients and

    nasal

    carriers

    Rapid

    Strep

    Tests, or

    throat

    culture

    and

    bacitracin

    suscep-

    tibility

    Use

    precautio

    n droplet

    for

    infants

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    Di Si d P th R i / L b P ti t

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    Disease Signs and

    Symptoms

    Patho-

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Legione

    llosis

    (Legion

    naires

    Disease,Pontiac

    Fever

    Anorexia,

    malaise,

    myalgia,

    headache,

    high fever,chills, and

    dry cough

    followed by

    aproductive

    cough,

    shortness

    of breath,

    diarrhea

    Legionella

    pneomophi

    la

    Environmen

    tal water

    sources, AC

    system,

    spa, hottubs, tap

    water,

    fountains,

    dust,transmissio

    n via

    aerosol of

    Legionella

    spp.

    Sputum

    and blood

    specimens

    sent to

    themicrobiolo

    gy lab for

    C&S;

    immunodiagnostic

    procedure

    s, such as

    antigen

    detection

    Use

    standard

    precautio

    ns

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    Diseasco Signs and Patho Reservoirs/ Labora Patient

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    Diseasco

    ugh,

    sore

    troat,

    chest e

    Signs and

    Symptoms

    Patho-

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Labora-

    tory

    Diagnosis

    Patient

    Care

    Mycopla

    smal

    Pneumo

    nia(Primary

    Atypical

    Pneumo

    nia)

    Headache,

    malaise,

    dry cough,

    sorethroat,

    chest

    discomfort

    Mycoplas

    ma

    pneumonia

    e

    Infected

    humans;

    trasmission

    via dropletinhalation

    or direct

    contact

    withinfected

    person or

    contaminat

    ed articles

    Demonstr

    ation of a

    rise in

    antibodytiter

    between

    acute and

    convalescent sera

    Use

    droplet

    precautio

    ns

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    Cross section of lung tissue

    with Mycoplasma pneumonia

    abscesses.

    Disease Signs and Patho Reservoirs/ Laborator Patient

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    Disease Signs and

    Symptoms

    Patho-

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Laborator

    y

    Diagnosis

    Patient

    Care

    Tubercul

    osis (TB)

    Malaise,

    fever, night

    sweats,

    weight loss

    and

    productive

    cough,

    shortness

    of breath,chest pain,

    hemoptysi

    s, and

    hoarseness

    Mycobacte

    rium

    tuberculosi

    s complex

    Infected

    humans,

    infected

    mammals;

    transmissio

    n via

    airborne

    droplets,

    directcontact

    with

    infected

    individuals

    Acid-fast

    bacilli

    (AFB),

    susceptibil

    ity testing,

    PPD

    tuberculin

    skin test

    Airborne

    precautio

    ns for

    pulmonar

    y or

    laryngeal

    disease,

    Standard

    precautions for

    extrapulm

    onary or

    meningial

    TB

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    Disease Signs and Patho Reservoirs Laboratory Patient

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    Disease Signs and

    Symptoms

    Patho-

    gen/

    Causativ

    e Agent

    Reservoirs

    /

    Mode of

    Trans-

    mission

    Laboratory

    Diagnosis

    Patient

    Care

    Whoppi

    ng

    cough

    (Pertusis)

    FIRST

    STAGE:

    mild,

    coldlikesymptoms

    SECOND

    STAGE:

    severe

    uncontrolla

    ble

    coughing

    fits

    Bordetell

    a

    pertusis

    Infected

    humans;

    transmissio

    n viadroplets

    produced

    by

    coughing

    Nasopharyng

    eal aspirates

    or swabs

    sent to themicrobiology

    lab;

    molecular

    diagnostic

    and

    immunodiag

    nostic are

    available

    Use

    droplet

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    Disease Signs and Patho- Reservoirs/ Laboratory Patient

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    Disease Signs and

    Symptom

    s

    Patho-

    gen/

    Causativ

    e Agent

    Reservoirs/

    Mode of

    Trans-

    mission

    Laboratory

    Diagnosis

    Patient

    Care

    Coccidioi

    domycos

    is (Valley

    Fever)

    Fever,

    chills,

    cough

    and

    rarely,pain, may

    include

    lung

    lesions,and

    abscesses

    througho

    ut the

    body

    Coccidioi

    des

    immitis

    Arthrospores

    present in

    soil in arid

    and semi

    arid areas ofthe Western

    Hemispheres

    ;

    transmissionvia

    inhalation of

    arthrospores

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    Disease Signs and Patho Reservoirs/ Labora-tory Patient

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    Disease Signs and

    Symptom

    s

    Patho

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Transmission

    Labora tory

    Diagnosis

    Patient

    Care

    Cryptoc

    occosis

    Subspecie

    s of C.

    neoforma

    ns

    Pigeon nests;

    pigeon,

    chicken ,

    turkey, and

    batdroppings

    Sensitive

    cryptococcal

    antigen

    detection

    test

    Standard

    precautio

    ns

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    Disease Signs and Patho Reservoirs/ Labora-tory Patient

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    Disease Signs and

    Symptom

    s

    Patho

    gen/

    Causative

    Agent

    Reservoirs/

    Mode of

    Transmission

    Labora tory

    Diagnosis

    Patient

    Care

    Histopla

    smosis

    Malaise,

    fever,

    chills,

    headache

    , myalgia,chest

    pains,

    and

    unproduc

    tive

    cough

    Histoplas

    ma

    capsulatu

    m var.

    capsulatum

    Warm, moist

    soil

    containing a

    high organic

    content andbird

    droppings,

    bat

    droppings

    and pigeon

    roosts.

    transmission

    via

    inhalation of

    Giemsa- or

    Wright

    stained

    smears of

    ulcerexudates,

    bone

    marrow,

    sputum and

    blood. skin

    tests and

    immunodiag

    nostic

    procedures

    Standard

    precautio

    ns

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    Disease Signs and Patho Reservo Labora-tory Patient

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    Disease Signs and

    Symptoms

    Patho

    gen/

    Causativ

    e Agent

    Reservo

    irs/

    Mode

    of

    Transmission

    Labora tory

    Diagnosis

    Patient

    Care

    Pneumo

    cystis

    CariniiPneumo

    nia

    (PCP,

    Interstit

    ial

    Plasma-

    Cell

    Pneomo

    nia)

    Fever,

    difficulty in

    breathing,dry cough,

    cyanosis

    and

    pulmonary

    infiltration

    of alveoli

    with frothy

    exudat

    Pneomo

    cystis

    jiroveci(formerl

    y P.

    carinii

    Infected

    humans

    ;transmission is

    perhaps

    via

    direct

    contact

    or

    airborn

    e

    Demonstration

    of Pneumocystis

    in material frombronchial

    brushing, open

    lung biopsy, lung

    aspirates or

    smears of

    tracheobronchial

    mucus by various

    staining methods

    Standard

    Precautio

    ns;do notplace PCP

    patients

    in the

    same

    room

    with an

    immunoc

    ompromis

    ed

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    Disease Signs and Patho Reservoir Labora-tory Patient

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    sease S g s a d

    Symptoms

    at o

    gen/

    Causativ

    e Agent

    ese o

    s/

    Mode of

    Transmiss

    ion

    abo a to y

    Diagnosis

    at e t

    Care

    Pulmo-

    nary

    Zygomy-cosis

    Wide

    range of

    clinicalmanifestati

    on

    Species

    of

    Mucor,Rhizopus

    , and

    Absidia

    Transmiss

    ion is by

    inhalationof

    airborne

    spores,ing

    estionand direct

    inoculatio

    n

    Microscopic

    observation of

    distinctive,ribbon-like

    braod aseptate

    hyphae in

    tissue sectionsand by culture

    of biopsy tissue

    Use

    Standard

    Precautions

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