15TH ANNUAL

COMPLEXCORONARY & VASCULARCASES

To Register and Obtain Additional Symposium Details Visit

www.cccsymposium.org

LIVE SYMPOSIUM OF

Presented by The Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health of Mount Sinai School of MedicineSponsored by The Page and William Black Post-Graduate School of Medicine of Mount Sinai School of Medicine

FELLOWS REGISTRATION FEES WAIVED!

CORONARY SYMPOSIUM DIRECTORSSamin K. Sharma, MD , FACC, FSCAIAnnapoorna S. Kini, MD, MRCP, FACC

CORONARY SYMPOSIUM CO-DIRECTORSPedro Moreno, MD, FACCMichael C. Kim, MD, FACCGeorge Dangas, MD, PhD, FACC, FSCAI Roxana Mehran, MD, FACC, FSCAIRobert Pyo, MD

VASCULAR SYMPOSIUM DIRECTORPrakash Krishnan, MD, FACC

VASCULAR SYMPOSIUM CO-DIRECTORSJ. Michael Bacharach, MD, FACC, FSCAIPeter L. Faries, MDJose Wiley, MD, FACC, FSCAI

NURSE / TECHNOLOGISTSYMPOSIUM DIRECTORSRobin Krinsky, RN-BC, CCRNAntonietta Tolentino, ANP-C

• Complex Coronary Intervention Unprotected Left Main, Calcified, Bifurcation, and Chronic Total Occlusion

• Endovascular Intervention Iliac, Femoral, Renal and Carotid

• Structural Heart Disease Intervention Valvuloplasty, Percutaneous Valve Replacement, Septal Ablation, PFO/ASD Closure

JUNE 13-16, 2012New York, New York

FINAL BROCHURE

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Dear Colleague,We would like to welcome you to the Fifteenth Annual 2012

Live Symposium of Complex Coronary and Vascular CasesThe field of Interventional Cardiology and Endovascular Interventions continues to evolve, with the rapid growth of available established and new technology supplemented constantly by the results of the latest randomized trials and registries. As practicing interventionalists, we must continually make changes to appropriately treat coronary, valvular, and peripheral vascular disease based on the available devices, therapy and trial results. Recently the appropriateness of revascularization; medical therapies, PCI or CABG for any given patient has become the area of intense scrutiny. Hence, we need to participate in continuing educational activities to remain current. The issue of experience and cost-effectiveness of a new technology or technique always needs to be weighed against the established practices, before making any decision in our daily practice.

That is exactly what we plan to achieve at our Complex Coronary and Vascular Cases Symposium; to present concise and current important information that will update you on the latest techniques and technologies and help clarify areas of diagnostic and therapeutic controversy. We plan to present the interventional format consistent with the guidelines for appropriateness of coronary revascularization. To further expand the field of endovascular specialty, we have continued to have a dedicated one-day vascular symposium on June 15th, format of which will be similar to the coronary symposium with live cases and didactic discussion.

The primary focus of this course is to present a multi-device approach to complex revascularization of patients with complex coronary and cardiovascular disease. Various novel interventional devices such as transcatheter aortic-valve implantation and renal artery denervation, and newer techniques such as retrograde CTO recanalization and dedicated bifurcation stenting will be demonstrated using live case presentations as platform for discussion by the operators, panelists and audience. The program is complemented by unbiased commentary of live cases by world-renowned experts and discussions intended to bring out general consensus regarding the most effective appropriate strategy that you can apply immediately in your practice.

In addition, the course will present updates on the common topics of controversy we frequently encounter in the field of interventional cardiovascular medicine. These updates will supplement the live cases with an up-to-date, comprehensive review of the most important and controversial topics of the current year.

We are committed to offer the 2012 Live Symposium as a platform for continued innovation in interventional cardiovascular medicine with the main interest of achieving safe procedural outcomes and strong emphasis on the appropriateness of the revascularization choice.

We look forward to seeing you at this year’s Symposium!

Sincerely,

Samin K. Sharma, MD, FACC, FSCAICoronary Course Director

Annapoorna S. Kini, MD, MRCP, FACCCoronary Course Director

Prakash Krishnan, MD, FACCVascular Course Director

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Symposium OverviewThe primary focus of this course is to present a multidevice approach to revascularization of patients with complex coronary and cardiovascular disease. The role of physiological and anatomical assessment using fractional flow reserve (FFR), IVUS and newer imaging techniques of near infrared spectroscopy (LipiScan) and Optical Coherence Tomography (OCT), in guiding interventions will be highlighted. Various novel interventional devices and techniques such as distal protection device, septal ablation, valvuloplasty, percutaneous valve replacement, thrombectomy, and complex peripheral vascular intervention will be emphasized. Technical issues regarding treatment of emerging problems such as unprotected left main disease, DES restenosis, bifurcation lesions, total occlusions, thrombotic lesions, carotid and peripheral lesions, and adjunct pharmacotherapy will be emphasized by the faculty using live case presentations as platforms for discussion.

Appropriateness of a revascularization choice and evidence-based practice guidelines will be discussed while simple and complex live cases are performed. Within the live case format, current topics will be presented to provide interventional cardiologists and vascular interventionalists with state-of-the-art information for managing patients as the dynamic field of interventional cardiology and vascular intervention continues to evolve. Through discussion and viewing of live cases, we expect to emphasize the long-term role of interventional cardiology in managing particular lesion subsets.

TARGET AUDIENCEThis course is specifically designed for:• Interventional Cardiologists who manage patients with complex, challenging anatomy for revascularization• Interventional Radiologists and Vascular Surgeons• Cardiology Fellows with an interest in Interventional Cardiology• Nurses, Technicians, and other Allied Health Care Professionals who work in Cardiac Catheterization and Vascular Laboratories

EDUCATIONAL OBJECTIVESThe overall goal of this program is to enhance knowledge and improve understanding of various interventional techniques and devices with management of various cardiac disease states.

Upon completion of this program, participant should be able to: • Compare and contrast the use of appropriate devices to facilitate stent delivery and expansion in complex cases. • Assess the plan for the best interventional strategy and adjust therapy by the data provided during live case discussion and presentations.• Apply case selection and choose the appropriate interventional devices for peripheral vascular disease.• Identify and select the appropriate techniques for treatment of structural heart disease.• Demonstrate the revascularizations/Percutaneous Coronary Interventions and CABG for patients with advanced coronary artery disease.

ACCREDITATIONThe Mount Sinai School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATIONThe Mount Sinai School of Medicine designates this live activity for a maximum of 16.25 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Credits apply to June 14-15, 2012 (Coronary Symposium and Vascular Symposium).

VERIFICATION OF ATTENDANCEVerification of attendance will be provided to all professionals.

SPECIAL NEEDSThe Mount Sinai School of Medicine is in full compliance with provisions of the Americans with Disabilities Act (ADA) and is accessible for individuals with special needs. If you would like to attend this conference and require any special needs or accommodations, please contact the Page and William Black Post-Graduate School of Medicine at 212-731-7950.

FACULTY DISCLOSUREIt is the policy of MSSM to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. Presenters must also make a meaningful disclosure to the audience of their discussions of unlabeled or unapproved drugs or devices. This information will be available as part of the course materials.

2012 FacultyCORONARY SYMPOSIUM DIRECTORSSamin K. Sharma, MD, FACC, FSCAIDirector, Clinical & Interventional CardiologyPresident, Mount Sinai Heart NetworkDean, International Clinical AffiliationsZena & Michael A. Wiener Professor of MedicineThe Mount Sinai Medical CenterNew York, New York

Annapoorna S. Kini, MD, MRCP, FACC Professor of MedicineDirector, Cardiac Catheterization LaboratoryDirector, Interventional Fellowship ProgramThe Mount Sinai Medical CenterNew York, New York

CORONARY SYMPOSIUM CO-DIRECTORS Pedro Moreno, MD, FACCProfessor of Medicine, CardiologyDirector, Translational Research, Cardiac Cath LabThe Mount Sinai Medical CenterNew York, New York

Michael C. Kim, MD, FACCAssistant Professor of Medicine, CardiologyDirector, Coronary Care UnitThe Mount Sinai Medical CenterNew York, New York

George Dangas, MD, PhD, FACC, FSCAIProfessor of Medicine, CardiologyDirector, Cardiovascular InnovationThe Mount Sinai Medical CenterNew York, New York

Roxana Mehran, MD, FACC, FESC, FSCAIProfessor of MedicineDirector of Interventional Cardiovascular Research and Clinical Trials UnitThe Mount Sinai Medical CenterNew York, New York

Robert Pyo, MDAssistant Professor of CardiologyThe Mount Sinai Medical CenterNew York, New York

MOUNT SINAI FACULTY: CORONARYValentin Fuster, MD, PhD, MACCDirector, Mount Sinai Heart Physician in ChiefProfessor of Medicine, Cardiology

Jeffrey Bander, MDAssistant Professor of Medicine, Cardiology

Usman Baber, MDAssistant Professor of Medicine, Cardiology

George Fernaine, MD, FACC, FSCAIAssistant Clinical Professor of Medicine, Cardiology

Jason Kovacic, MD, PhD, FSCAIAssistant Professor of Medicine

Atul M. Limaye, MD, MRCPAssistant Professor of Medicine, Cardiology

Barry A. Love, MDAssistant Professor of Pediatrics Director, Pediatric Cardiac Catheterization Sameet Palkhiwala, MD, FACCAssistant Clinical Professor

Javed Suleman, MD, FACC, FSCAIAssociate Clinical Professor Joseph M. Sweeny, MDAssistant Professor of Medicine, Cardiology

CORONARY SYMPOSIUM GUEST FACULTYVinay K. Bahl, MDProfessor & Head, Department of CardiologyAll India Institute of Medical SciencesNew Delhi, India

Harinder K. Bali, MDDirector of CardiologyFortis HospitalMohali, India

Antonio Colombo, MD, FACC, FSCAIDirector, Cardiac Catheterization LaboratoryEMO GVM Centro Cuore Columbus and San Raffaele HospitalMilan, Italy

Carlo Di Mario, MD, PhD, FACC, FSCAIProfessor of Clinical CardiologyRoyal Brompton HospitalLondon, United Kingdom

D. S. Gambhir, MD, FACC, FSCAIDirectorKailash Hospital Heart InstituteNoida Delhi, India

B K Goyal, MD, FSCAIDirector, Interventional CardiologyBombay Hospital and Medical ResearchMumbai, India

James B. Hermiller, MD, FACC, FSCAIDirector of Interventional CardiologySt. Vincent Heart Center of IndianaIndianapolis, Indiana

Samir Kapadia, MD, FACC, FSCAIDirector, Sones Cardiac Cath LabsCleveland ClinicCleveland, Ohio

Saibal Kar, MD, FACC, FSCAIDirector, Interventional Cardiac ResearchCedars-Sinai Medical CenterLos Angeles, California

John M. Lasala, MD, PhD, FACC, FSCAIDirector Interventional CardiologyWashington University School of MedicineSt. Louis, Missouri

Raj Makkar, MD, FACC, FSCAIDirector, Interventional Cardiology and Cardiac Catheterization LaboratoryCedars-Sinai Medical CenterLos Angeles, California

Sameer Mehta, MD, MBA, FACCVoluntary Associate Professor of MedicineUniversity of MiamiMiami, Florida

Gary S. Mintz, MD, FACCChief Medical OfficerCardiovascular Research FoundationNew York, New York

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DB Pahlajani, MDSenior Physician Nanavati HospitalMumbai, India

Augusto D. Pichard, MD, FACC, FSCAIDirector, Cardiac Catheterization LaboratoryWashington Hospital CenterWashington, DC

Jeffrey J. Popma, MD, FACC, FSCAIDirector, Interventional Cardiology Clinical ServicesBeth Israel Deaconess Medical CenterBoston, Massachusetts

Charanjit S. Rihal, MD, MBA, FACC, FSCAIChair, Division of Cardiovascular DiseaseMayo ClinicRochester, Minnesota

Alfredo E. Rodriguez, MD, PhD, FACC, FSCAIHead Director, Cardiac UnitCardiovascular Research CenterBuenos Aires, Argentina

Mathew Samuel K, MD, FACC, FSCAIDirector, Cardiac Catheterization LabApollo HospitalsChennai, India

Satyavan Sharma, MD, FACC, FSCAIProfessor and Head of CardiologyBombay Hospital and Medical Research CentreMumbai, India

Gregg W. Stone, MD, FACC, FSCAIProfessor of Medicine, Columbia University Medical CenterDirector of Cardiovascular Research FoundationNew York, New York

Paul S. Teirstein, MD, FACC, FSCAIDirector of Interventional CardiologyScripps ClinicLaJolla, California

Ron Waksman, MD, FACC, FSCAIAssociate Director, Division of CardiologyWashington Hospital CenterWashington, DC

Sudhir Vaishnav, MDInterventional CardiologistLilavati Hospital and Research Centre Mumbai, India

VASCULAR SYMPOSIUM DIRECTORPrakash Krishnan, MD, FACCDirector, Endovascular InterventionAssistant Professor of MedicineThe Mount Sinai Medical Center New York, New York

VASCULAR SYMPOSIUM CO-DIRECTORSJ. Michael Bacharach, MD, FACC, FSCAISection Head, Vascular Medicine and Peripheral Vascular InterventionNorth Central Heart Institute Sioux Falls, South Dakota

Peter L. Faries, MDChief of Vascular SurgeryThe Mount Sinai Medical CenterNew York, New York

Jose Wiley, MD, FACC, FSCAIAssistant Professor of Medicine and RadiologyThe Mount Sinai Medical CenterNew York, New York

MOUNT SINAI FACULTY: VASCULARDaniel Soffer, MD, FACC, FSCAIAssistant Professor of Medicine

Robert Lookstein, MDAssociate Professor of Radiology and Surgery

Vivek Reddy, MDProfessor of Cardiology

Stanley Tuhrim, MDProfessor, Neurology

Jonathan A. Winston, MDProfessor, Nephrology

VASCULAR SYMPOSIUM GUEST FACULTYAnvar Babaev, MD, PhD, FSCAIDirector, Peripheral InterventionNew York University Medical CenterNew York, New York

Mark W. Burket, MD, FACC, FSCAIDirector of Vascular MedicineUniversity of Toledo Medical CenterToledo, Ohio

Tyrone J. Collins, MD, FACC, FSCAIDirector, Cardiac Catheterization LaboratoryOchsner Medical CenterNew Orleans, Louisiana

Andrey Espinoza, MD, FACC, FSCAIMedical Director, Cardiac Cath LabHunterdon Medical CenterFlemington, New Jersey

Christopher L. Gade, MD, FACC, FSCAIAssistant Professor of Medicine, CardiologyWeill Cornell Medical College / New York PresbyterianNew York, New York

Daniel H. Gruenstein, MD, FSCAIDirector of Pediatric Interventional CardiologyUniversity of Minnesota AmplatzChildren’s HospitalMinneapolis, Minnesota

Amir Kaki, MD, FACC, FSCAIAssistant Professor of Medicine, CardiologyWeill Cornell Medical College / New York PresbyterianNew York, New York

James F. McKinsey, MD, FACSChief, Division of Vascular Surgery and Endovascular InterventionNY Presbyterian Hospital / Columbia UniversityNew York, New York

Peter L. Smith, MDDirector, The Vascular InstituteBayonne Medical Center Bayonne, New Jersey

Michael J. Trepal, DPM, FACFASVP for Academic Affairs and DeanNew York College of Podiatric Medicine New York, New York

Craig M. Walker, MD, FACCInterventional CardiologistCardiovascular Institute of the SouthHouma, Louisiana

Mark H. Wholey, MD, FSCAIDirector, Peripheral Vascular InterventionsUniversity of Pittsburgh Medical Center ShadysidePittsburgh, Pennsylvania

NURSE / TECHNOLOGIST SYMPOSIUM DIRECTORSRobin Krinsky, RN-BC, CCRNNurse Educator/ClinicianThe Mount Sinai Medical CenterNew York, New York

Antonietta Tolentino, ANP-CAdult Nurse PractitionerThe Mount Sinai Medical CenterNew York, New York

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2012 Faculty 2012 Faculty

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Special Events / Industry Workshop

Wednesday, June 13th

Saturday, June 16th

Complex Cardiovascular Topics*7:00 p.m. Registration / Cocktails, Buffet Dinner Sheraton NY Hotel and Towers7:30 p.m. Emerging Stent Design and Coatings: Absorb Trial Pedro Moreno, MD7:50 p.m. Chronic Total Occlusions Recanalization: Expert CTO Trial Annapoorna S. Kini, MD8:10 p.m. Unprotected Left Main Intervention: EXCEL Trial Samin K. Sharma, MD8:30 p.m. DAPT Interruption Post DES: Xience V Meta Analysis Michael C. Kim, MD8:50 p.m. Carotid Stenting: CHOICE Trial Prakash Krishnan, MD9:10 p.m. Panel Discussion 9:30 p.m. Conclusion

(Workshops to be held at the Sheraton NY Hotel and Towers)

Interventional Board Review 2012* 8:00 a.m. – 12:00 p.m. Sheraton NY Hotel and Towers

This course is designed to prepare interventional cardiologists and fellows for the Interventional Board by providing the updated practical clinical aspect of various interventional subjects. Most of the education will be performed as multiple choice Q&A, with explanations for the correct choice as well as short case presentations and discussion. Key findings of randomized trials will be presented in the simple Q&A format. An expert faculty has been selected to deliver state-of-the-art, in depth discussion of the subject.

8:00 a.m. Vascular Biology and Atherosclerosis Pedro Moreno, MD8:30 a.m. Antiplatelet and Antithrombotic Therapy George Dangas, MD, PhD9:00 a.m. Vascular Access and VCD Michael C. Kim, MD9:30 a.m. Important Tips in Peripheral Arterial Disease Prakash Krishnan, MD

10:00 a.m. BREAK

10:10 a.m. Coronary Anatomy and Physiology Annapoorna S. Kini, MD 10:40 a.m. IVUS; Interpretation in Day-to-Day Practice Tony J. De Martini, MD 11:10 a.m. Interventional Devices and Trials; Q & A Samin K. Sharma, MD

12:00 p.m. LUNCH

Cardiovascular Case Discussion* India Breakout Session1:00 p.m. – 5:00 p.m. Sheraton NY Hotel and Towers This course is designed to update Interventional Cardiologists on how to choose the appropriate revascularization methods based on physiologic imaging and angiography; deciding whether to intervene or not intervene. The attendee will also be able to formulate evidence-based and state-of-the-art interventional strategies during these presentations. An expert faculty will present key findings of selected appropriate devices and techniques for stent delivery and expansion inpatients with complex cases. “Taking On The Tough Ones” 1:00 p.m. CAD Burden in the South Asian Population Jagat Narula, MD1:20 p.m. Overview of Interventional Cardiology 2012 Samin K. Sharma, MD1:45 p.m. BREAK2:00 p.m. – 4:00 p.m.“Disease State Overview & Complex Case Presentations” Complex Coronary Cases..............Samin K. Sharma, MD, DB Pahlajani, MDPanel Case Presentations: Sumeet Sethi, MD, Anand Srinivas, MDChronic Total Occlusions Cases...........................Annapoorna S. Kini, MDPanel Case Presentations: Sharad Chandra, MD, Lingaraj Nath, MD Bifurcation Cases...........................................................D.S. Gambhir, MDPanel Case Presentations: Satya Gupta, MD, Uthaya Kumaran Kalaichevan, MD, Sudhir Vaishnav, MD Left Main Intervention.............................................Harinder K. Bali, MDPanel Case Presentations: Pakshirajan Balaji, MD , Rajneesh Jain, MD, Bhaskar Rao, MD 4:00 p.m. – 5:00 p.m. Managing Complications: Case Review & Panel Discussion

*All workshops are not CME Accredited

To register for the Wednesday Evening Symposium or the Saturday Workshops, please complete and return the Registration Form, or Register Online at: www.cccsymposium.org

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Agenda | Nurse/Technologist Symposium

Wednesday, June 13th8:00 a.m. Registration / Continental Breakfast Mount Sinai Hospital, Stern Auditorium

8:30 a.m. Welcome Address / Program Overview Robin Krinsky, RN-BC, MSN, CCRN

8:45 a.m. Top Ten Advances of Interventional Cardiology 2011 Samin K. Sharma, MD

9:15 a.m. PCI: A Look Back...A Look Ahead Antonietta Tolentino, ANP-C

9:35 a.m. Multi-Modality Imaging During PCI Pedro Moreno, MD

10:00 a.m. BREAK / VISIT EXHIBITS

10:15 a.m. State of Peripheral Intervention Prakash Krishnan, MD

10:40 a.m. Status of Radial Intervention in the USA Robin Krinsky, RN-BC, MSN, CCRN

11:00 a.m. Role of Cardiac Rehabilitation Post MI/ PCI Maryann McLaughlin, MD

11:25 a.m. Aggressive Risk-Factor Modification Post PCI Peggy O’Boyle, NP

11:45 a.m. LUNCH AND TOUR OF THE CATH LAB

1:15 p.m. STEMI Update 2012 Annapoorna S. Kini, MD

1:35 p.m. Highlights in Transcatheter Aortic Valve Replacement Melissa Mattimore, ANP-BC

1:55 p.m. LV Assist Devices: Emerging Role Sean Pinney, MD

2:15 p.m. New Developments in Antithrombotic Therapy Tanya Sullivan, NP

2:35 p.m. BREAK / VISIT EXHIBITS

2:50 p.m. Pathology in Hemodynamic Recordings Michael C. Kim, MD

3:05 p.m. Bridging Evidence in Interventional Cardiology Roxana Mehran, MD

3:20 p.m. Prevention of Contrast Nephropathy Surekha Patel, ANP-C

3:40 p.m. Radiation Safety: Avoiding Hazards of the Beam Javier Hernandez, RT (R)

4:00 p.m. Closing Remarks/Conclusion/Awarding of Contact Hours Antonietta Tolentino, ANP-C

4:30 p.m. WINE & CHEESE RECEPTION IN EXHIBIT HALL

6.0 CEU’s will be provided for registered Nurses and Cardiovascular Professionals

Wednesday, June 13th6:00 p.m. – PRE-REGISTRATION 8:00 p.m. Sheraton NY Hotel & Towers, Lower Lobby

Thursday, June 14th 7:00 a.m. Registration / Continental Breakfast Mount Sinai Hospital, Stern Auditorium

7:40 a.m. Welcome: Introduction – Top Ten Advances of Interventional Cardiology 2011 Samin K. Sharma, MD

8:15 a.m. Welcome: Lessons Learned From HRP Study 2012 Valentin Fuster, MD, PhD

8:45 a.m. Live Case Presentations #1, #2 and #3: Bifurcation and Calcified Lesions Moderator: George Dangas, MD, PhD Panelists: Antonio Colombo, MD, Raj Makkar, MD, Gary S. Mintz, MD, Augusto D. Pichard, MD, Alfredo E. Rodriguez, MD, Mathew Samuel K, MD

10:20 a.m. DEBATE #1: DES Controversy Everolimus Eluting Stent is the Best................................................James B. Hermiller, MD Zotarolimus Eluting Stent is the Best..........................................Alfredo E. Rodriguez, MD Newer DES & BVS Will Prevail............................................................Mathew Samuel K, MD BMS Will Prevail in Half.........................................................................Augusto D. Pichard, MD

11:00 a.m. BREAK / VISIT EXHIBITS

11:15 a.m. KEYNOTE LECTURE #1: IVUS vs. OCT for PCI Optimization..............Gary S. Mintz, MD 11:35 a.m. Live Case Presentations #4 and #5: Left Main and Bifurcation Lesions Moderator: George Dangas, MD, PhD Panelists: Harinder K. Bali, MD, Antonio Colombo, MD, Raj Makkar, MD, Sameer Mehta, MD, Gary S. Mintz, MD, Alfredo E. Rodriguez, MD

12:45 p.m. LUNCH / VISIT EXHIBITS

1:30 p.m. Live Case Presentations #6 and #7: Chronic Total Occlusions Moderator: Pedro Moreno, MD Panelists: Vinay K. Bahl, MD, Harinder K. Bali, MD, Jeffrey Bander, MD, John M. Lasala, MD, Sameer Mehta, MD, Augusto D. Pichard, MD, Mathew Samuel K, MD

2:30 p.m. DEBATE # 2 Myocardial Regeneration: It Works..................................................................Raj Makkar, MD Myocardial Regeneration: Ineffective Expansive Research Tool...Sameer Mehta, MD DEBATE # 3 Bifurcation Lesion PCI: One Stent Strategy is the Best.................James B. Hermiller, MD Bifurcation Lesion PCI: Two Stent Strategy is Preferred..................Antonio Colombo, MD 3:10 p.m. Live Case Presentations #8, #9, and #10: Cardiovascular Cases–TPVR, BMV, HOCM Moderator: Michael C. Kim, MD Panelists: Vinay K. Bahl, MD, James B. Hermiller, MD, John M. Lasala, MD, Raj Makkar, MD, Sameer Mehta, MD, Augusto D. Pichard, MD

4:15 p.m. Complex Cases / Complications Cine Review Moderator: Samin K. Sharma, MD Presenters: Harinder K. Bali, MD, Vinay K. Bahl, MD, Robert Pyo, MD

5:00 p.m. Concluding Remarks...................................................................................Samin K. Sharma, MD

7:00 p.m. – GALA SOCIAL EVENT – Dinner Cruise Around Manhattan 10:00 p.m. (Buses Depart the Sheraton NY Hotel & Towers at 6:40 p.m.)

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Agenda | Coronary Symposium

Friday, June 15th 7:00 a.m. Continental Breakfast Mount Sinai Hospital, Stern Auditorium7:55 a.m. Welcome and Introduction Samin K. Sharma, MD8:00 a.m. DEBATE #4 Appropriateness of the Appropriate Use Criteria.................................Samin K. Sharma, MD An Inappropriate Look at Appropriate Use Criteria...............................Paul S. Teirstein, MD DEBATE #5 Minimum DAPT Duration Post DES: 1+ Year.............................................Samir K. Kapadia, MD Minimum DAPT Duration Post DES: <1 Year..................................................Michael C. Kim, MD

8:40 a.m. Live Case Presentations #11, #12, and #13: Bifurcation and Calcified Lesions Moderator: Roxana Mehran, MD Panelists: Carlo Di Mario, MD, D.S. Gambhir, MD, Samir Kapadia, MD, Charanjit S. Rihal, MD, Paul S. Teirstein, MD, Ron Waksman, MD

10:10 a.m. Live Case Presentation #14: CoreValve TAVR Case Satellite Transmission From: University Hospital Bonn, Germany Operator: Eberhard Grube, MD, FACC, FSCAI Moderator: Roxana Mehran, MD Panelists: Carlo Di Mario, MD, Samir Kapadia, MD, DB Pahlajani, MD, Charanjit S. Rihal, MD, Paul S. Teirstein, MD, Ron Waksman, MD

10:40 a.m. KEYNOTE LECTURE #2: In Search of Vulnerable Plaque?.........................................................................Gregg W. Stone, MD

11:00 a.m. BREAK / VISIT EXHIBITS

11:15 a.m. Live Case Presentations #15 and #16: Left Main and Bifurcation Lesions Moderator: Roxana Mehran, MD Panelists: D.S. Gambhir, MD, B K Goyal, MD, Saibal Kar, MD, Charanjit S. Rihal, MD, Gregg W. Stone, MD, Paul S. Teirstein, MD, Sudhir Vaishnav, MD

12:45 p.m. LUNCH / VISIT EXHIBITS

1:30 p.m. Live Case Presentations #17 and #18: Chronic Total Occlusion Moderator: Pedro Moreno, MD, FACC Panelists: Carlo Di Mario, MD, Saibal Kar, MD, Jeffrey J. Popma, MD, Satyavan Sharma, MD, Gregg W. Stone, MD, Ron Waksman, MD

2:30 p.m. DEBATE #6: Invasive Lesion Assessment Adjunct to PCI FFR is Supreme............................................................................................................Carlo Di Mario, MD IVUS is Very Useful.....................................................................................................Ron Waksman, MD NIRS is Emerging: Yellow Trial.......................................................................Annapoorna S. Kini, MD

3:00 p.m. KEYNOTE LECTURE #3: Update in TAVI/TAVR Status: Emerging Indications.............................Jeffrey J. Popma, MD 3:20 p.m. Live Case Presentations #19 and #20: Cardiovascular Cases–Sapien TAVR, BMV Moderator: Michael C. Kim, MD Panelists: Carlo Di Mario, MD, B K Goyal, MD, Samir Kapadia, MD, Jeffrey J. Popma, MD, Charanjit S. Rihal, MD, Satyavan Sharma, MD, Sudhir Vaishnav, MD

4:30 p.m. Complex Cases / Complications Cine Review Moderator: Samin K. Sharma, MD Presenters: Saibal Kar, MD, Charanjit S. Rihal, MD, Satyavan Sharma, MD

5:00 p.m. Course Conclusion & Future Directions for the 16th Symposium Samin K. Sharma, MD

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Agenda | Coronary Symposium Agenda | Coronary Symposium

Friday, June 15th7:30 a.m. Continental Breakfast Mount Sinai Hospital, Hatch Auditorium

7:55 a.m. Welcome and Introduction Prakash Krishnan, MD

8:00 a.m. Management of Asymptomatic Carotid Artery Disease: Are the Negative Views on Medical Therapy Misinformed? Stanley Turhrim, MD

8:10 a.m. Proximal vs. Distal Protection During Carotid Stenting: How Do I Choose? Peter L. Faries, MD

8:20 a.m. Minor Strokes After CAS and Impact of MI’s and Cranial Nerve Injuries After CEA? What’s the Sustained Clinical Effect? J. Michael Bacharach, MD

8:30 a.m. The Results of CREST / ICSS / ACT1 Will Influence Treatment of Symptomatic and Asymptomatic Patients with Carotid Disease — How and in What Way? Mark H. Wholey, MD

8:40 a.m. Neuro-Rescue for the Carotid Interventionalist: Approach, Advice, Tips and Tricks Tyrone J. Collins, MD

8:50 a.m. Live Case Presentations: #1 and #2 Operators: Peter L. Faries, MD, Prakash Krishnan, MD, Jose Wiley, MD Moderator: J. Michael Bacharach, MD Panelists: Tyrone J. Collins, MD, Andrey Espinoza, MD, Stanley Tuhrim, MD, Mark H. Wholey, MD

10:30 a.m. BREAK / VISIT EXHIBITS

RENAL SYMPOSIUM10:40 a.m. Live Case Presentation #3: Renal Sympathetic Denervation Satellite Transmission From: Heart Center, Bad Krozingen, Germany Operators: Thomas Zeller, MD Moderator: J. Michael Bacharach, MD Panelists: Mark W. Burket, MD, Tyrone J. Collins, MD, George Dangas, MD, PhD, Andrey Espinoza, MD, Robert Lookstein, MD, Vivek Reddy, MD

11:15 a.m. Renal Sympathetic Denervation for Hypertension: What is the Available Data, Available Devices, and Future Impact? Mark W. Burket, MD

11:25 a.m. Renal Stenting is Near Death: Only Rare Niche Indications Remain Jonathan A. Winston, MD

11:35 a.m. Who are the Best Candidates for Renal Stent Placement and How Can We Predict Who Will Respond? Insights from Renal Stent Trials: Role of BNP? Role of IVUS, FFR? Robert Lookstein, MD

11:45 a.m. Live Case Presentation #4 Operators: Prakash Krishnan, MD, Jose Wiley, MD Moderator: J. Michael Bacharach, MD Panelists: Mark W. Burket, MD, Tyrone J. Collins, MD, Andrey Espinoza, MD, Robert Lookstein, MD, Vivek Reddy, MD

12:15 p.m. LUNCH / VISIT EXHIBITS

Agenda | Vascular Symposium

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Agenda | Vascular Symposium Agenda | Vascular Symposium

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Friday, June 15th PERIPHERAL ARTERY SYMPOSIUM1:20 p.m. State Of-The-Art Lecture Drug Delivery Will Be The New Standard in the SFA: Current Trials, Available Technology, and Future Directions James F. McKinsey, MD

1:40 p.m. Do Covered Stents Really Outperform Stents for Iliac Occlusive Disease and When Do I Use Them? Tyrone J. Collins, MD

1:50 p.m. Is Catheter-Based SFA Atherectomy Archaic or Will it Avoid Extinction in Concert with the Use of Drug Coated Technology? Mark W. Burket, MD

2:00 p.m. Brachiocephalic Intervention: Indications and Approach to Treatment J. Michael Bacharach, MD

2:10 p.m. Transpedal Approach and Pedal Arch Reconstruction Techniques in Treating Patients with CLI Craig M. Walker, MD

2:20 p.m. Live Case Presentations: #5 and #6 Operators: Prakash Krishnan, MD, Jose Wiley, MD Moderator: J. Michael Bacharach, MD Panelists: Tyrone J. Collins, MD, James F. McKinsey, MD, Craig M. Walker, MD, Mark H. Wholey, MD

3:30 p.m. BREAK / VISIT EXHIBITS

CONTROVERSIES, ANEURYSMS AND ULCERS Moderator: J. Michael Bacharach, MD

3:40 p.m. Update on Percutaneous ASD and PFO Closure? Where Are We Heading? Daniel H. Gruenstein, MD

3:50 p.m. EVAR: Should Be the Preferred Treatment for Abdominal Aneurysms Peter L. Faries, MD

4:00 p.m. Endovenous Thermal Ablation: Radiofrequency vs. Lasers: Is There a Difference? Jose Wiley, MD

4:10 p.m. The Work-Up, Acute Therapy, and Chronic Care of Arterial Ulcers Michael J. Trepal, DPM

4:20 p.m. Pudendal Artery Interventions and Erectile Dysfunction? Anvar Babaev, MD

4:30 p.m. Complex Endovascular Cases: Cine Review Moderator: Prakash Krishnan, MD Presenter: Christopher Gade, MD, Amir Kaki, MD, Peter L. Smith, MD Panelists: J. Michael Bacharach, MD, Mark W. Burket, MD, Tyrone J. Collins, MD, Andrey Espinoza, MD, Craig M. Walker, MD, Mark H. Wholey, MD 5:00 p.m. Course Conclusion & Future Directions for 2013 Symposium Prakash Krishnan, MD

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Coronary Case StudiesComplex Distal LM and 3V CAD PCI with Impella Assist

Complex LM and LAD Bifurcation PCI: ROTA, Simultaneous Kissing Stents (SKS) and DES

Multiple 80-90% LM/LAD/LCx Calcified Lesions

Multiple LM, LAD, and LCx Calicified Lesions

Final Results Post Rota and DES (Xience V X4)

Final Post SKS, LAD and LCx Rota DES (Xience V X4)

90% LM & Multiple 90% Prox-Mid LAD and 70% D2 Bifurcation Lesions

Complex LM and LAD/D2 Bifurcation Lesions

Post SKS in LM and 2 Xience V DES in LAD

Final Results Post (SKS LM and 2 Xience V DES in LAD) and Flextome PTCA of D2

Retrograde Ostial LAD CTO Recanalization via RCA Collaterals

100% Ostial LAD Total Occlusion; Distal Vessel Fills via RCA Collaterals

100% Ostial LAD CTO Fills via RCA Collaterals

Retrograde Fielder XT Wire advanced via RCA LAD Septal with Corsair

Final Results Post LAD DES (Resolute X2)

Impella RAO Cranial SKSRAO Caudal

RAO Caudal RAO Cranial SKSRota 1.75

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Retrograde RCA CTO Recanalization via LAD Septals

100 Ostial RPDA Occlusion Fills via LAD Septal Collaterals

Fielder XT Guide Wire via LAD Septal to RPDA and then to RCA

Fielder XT Guide Wire Exteriorized via RCA Guide Cather

Final Results Post DES Promus Element x2 in RPDA

Subtotal Diffuse Calcific LAD Disease Post Rota Burr (1.25mm) in LAD Post 3 Xience V DES: In Prox-Mid LAD Final Results Post Xience V DES X3

Diffuse Extensive CAD with Severe LV Dysfunction; Rota, DES PCI with Impella Assist

Cardiovascular Cases Studies

Transcatheter Aortic Valve Replacement (TAVR) for Severe Aoric Stenosis

Baseline Aortogram with Severe AS Inset: Baseline Hemodynamic: Mean Gradient 60 mmhg, AVA 0.6 cm2

BAV with 22/5.5 cm Z-med II Balloon Aortic Valvuloplasty

29 mm CoreValve Implantation Aortogram; No AI

Post TAVR Hemodynamic; MeanGradient 8mmhg and AVA 1.7 cm2

Impella

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Other Case Studies

Reduction in lipid plaque content on high dose statin as measured by near infrared spectroscopy (NIRS)

Baseline

Follow Up after 7 Weeks

Venture Catheter to Direct Wire to Native Anterior Tibial

Successful Cross Retrograde AT Wire Antegrade Popliteal Wire

Successful PTA Stent and Patent SFA Popliteal

Anterior Ischemia; High Grade Left Subclavian Artery Stenosis and Intervention

LIMA Patent

High Grade Stenosis of Left Subclavian Artery

Successful PTA/Stent Successful PTCA with Patent LIMA

LIMA

Successful PTCA

Patient with Critical Limb Ischemia; Successful Retrograde Cross and Intervention

Patent Distal Anastomosis

PatentFem/DP Bypass

AnteriorTibial ArteryOccluded

PoplitealArtery

Occluded SFA Occluded Popliteal Artery Retrograde Filling of Native Anterior Tibial

Patent Distal Anastomosis

Endovascular Case StudiesA Case of Plaque

Regression

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New York Citywww.nyctourist.com

Welcome to The Big Apple. Whether it’s magnificent shopping, fine dining, the theater or sightseeing, New York City has it all. With average temperatures in June around 75 degrees, there is no better time to visit and enjoy everything the city that never sleeps has to offer!

THEATERwww.newyorktheatre.com Seeing a show on Broadway and going to the theater in NYC is one of the most popular events for New York City tourists. See hit shows such as The Lion King, Wicked, Spiderman, Chicago, Mamma Mia, Mary Poppins, Sister Act and Jersey Boys.

MUSEUMS

Solomon R. Guggenheim Museum www.guggenheim.org

The American Museum of Natural Historywww.AMNH.org

STATUE OF LIBERTYwww.statueofliberty.orgLocated in New York Harbor, the Statue of Liberty was a gift of international friendship from France to the United States. Stroll into the lobby where you can experience the original torch and the Statue of Liberty Exhibit, then proceed to the promenade area for an up close view of the statue and a spectacular view of New York Harbor. Ferries depart Battery Park to the Statue between the hours of 8:30 a.m. – 6:00 p.m.

CENTRAL PARKwww.centralpark.comCentral Park features 843 acres of beautiful landscape filled with numerous attractions such as the Central Park Zoo and Wildlife Center and the Children’s Zoo. The park also has restaurants including the scenic Boathouse Restaurant.

The Museum of Modern Art Art www.MoMa.org

The Metropolitan Museum of Artwww. metmuseum.org

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2012 Symposium SupportersThe symposium is being funded in part through educational grants from medical device and pharmaceutical industries. The following is a preliminary list of supporters for the 2012 symposium. We appreciate their participation in this conference and their support of continuing medical education. A complete list of contributors and appropriate acknowledgement will be given to all supporters in the course syllabus.

St. Jude MedicalTerumo Medical Corporation

ABIOMED, Inc.AccessClosure, Inc. / Mynx

AstraZeneca Edwards LifesciencesVolcano Corporation

Acist Medical Systems / BraccoAngioscore, Inc.

B. Braun MedicalPhilips Medical Systems

Tryton MedicalVascular Solution, Inc.

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“Please express my thanks to Prakash Krishnan, MD for having me at the meeting. It was a great meeting and I really enjoyed it.”– Mark H. Wholey, M.D.

“It was an enjoyable meeting and a great pleasure to see the face of CAD treatment changing at Mount Sinai. You must be having the largest experience of PCI in patients of high syntax score using second generation DES. It will be interesting to see their 2 or 3 year follow-up data from your group. It will be an honor to be part of the 2012 meeting.” – Satyavan Sharma, M.D.

“It is always an honor to be a part of the Complex Coronary Faculty! It is an exceptional meeting.” – James B. Hermiller, M.D.

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Registration InformationThe registration fee for this CME activity is $400.00 for physicians who are members of SCAI (Society for Cardiovascular Angiography and Interventions) or ISIC (Indo-American Society of Interventional Cardiologists). The fee for physicians who are non-members of SCAI or ISIC is $600.00. A reduced registration fee of $200.00 is available for Residents, Nurses, Technicians and Mount Sinai Affiliates. The registration fee for Industry Personnel is $400.00. Fellows registration fees are WAIVED! Your registration fee includes attendance at the Wednesday, Thursday and Friday Sessions, course materials, continental breakfasts, refreshment breaks, lunches and a gala social event on Thursday evening. For questions regarding registration, please contact Gaffney Events, kate@gaffneyevents.com or 425.844.9019.

ONE-DAY REGISTRATION RATESThere are one-day registration rates available for both the Nurse / Technologist Symposium on Wednesday, June 13th and the Vascular Symposium on Friday, June 15th. The Nurse Technologist Symposium one-day rate is $75.00. The registration fee for the Vascular Symposium is $200.00 for physicians who are members of SCAI or ISIC. The one-day registration fee for physicians who are non-members of SCAI or ISIC is $300.00. A reduced registration fee of $100.00 is available for Residents, Nurses, Technicians and Mount Sinai Affiliates. The registration fee for Industry Personnel is $200.00.

EARLY BIRD DISCOUNT REGISTRATION RATES! Full Symposium Registration will be reduced by 25% if registration is received prior to Friday, May 25, 2012.

REFUNDS: Cancellations will be accepted through Friday, May 25, 2012 and are subject to a $50 cancellation fee. There will be no refund of tuition for cancellations received after that date. The Post-Graduate School for Continuing Medical Education must receive written notification of your intent to cancel before the cancellation deadline. No refund of tuition will be given for no-shows.

SYMPOSIUM LOCATIONMount Sinai School of MedicineAnnenberg BuildingStern Auditorium100 Street & Madison AvenueNew York, NY 10029

NOTE: Mount Sinai School of Medicine is located approximately 3 miles from the Sheraton New York Hotel & Towers. Attendees who are staying at this hotel will be provided with complimentary round-trip transportation between the hotel and the hospital on Thursday, June 14th and Friday, June 15th. There will also be a complimentary shuttle service running every half hour between the hotel and Mount Sinai Hospital.

HOTEL ACCOMMODATIONSSheraton New York Hotel & Towers811 Seventh Avenue, 53rd StreetNew York, NY 10019Guest Telephone: 212.581.1000Guest Fax: 212.262.4410

A block of rooms has been reserved at the Sheraton NY Hotel & Towers for attendees of the 2012 CCC Symposium at a special reduced rate of $309.00 single or double occupancy (per night), plus tax. To receive the discounted room rate, reservations must be confirmed by Saturday, May 19, 2012. After that date, reservations will be subject to space and rate availability. Please note, June is a very busy time in NYC. Hotel rooms will be scarce and your room rate will increase if your reservations are not made prior to the cut-off date.

Please contact the Reservations Department directly at 212.581.1000 or 888.625.5144 to request accommodations. When making your reservation, please be sure to mention that you will be attending the Mount Sinai Hospital Cardiology Symposium.

You may also book your room reservations directly online by visiting our website at www.cccsymposium.org.

TRANSPORTATIONThe Sheraton New York Hotel & Towers is located in midtown Manhattan. The hotel is 45 minutes from LaGuardia Airport and 60 minutes from the John F. Kennedy International Airport. Yellow Medallion Taxi service is available from LaGuardia Airport for approximately $30.00 (one way) and is available from the JFK International Airport for approximately $60.00 (one way). Rental car services are available at both airports. Hotel garage parking is available for $50.00 per 24 hours.

Fax registration form ONLY if payment is made by credit card.

CONTACT INFORMATION

Name:________________________________________________________________________Institution:_______________________________________________

Mailing Address: ________________________________________________________________________________________________________________

City: ____________________________________________________ State: _____________________________ Zip / Postal Code: ______________________

Office Phone: (_______)____________________________________________ Office Fax: (_______)____________________________________________

E-mail Address (required for registration confirmation):__________________________________________________________________________________

Professional Degree or Credential: o M.D. o D.O. o Ph.D. o R.N. o Other ________________________________________________________

REGISTRATION FEESFULL SYMPOSIUM REGISTRATION

Complex Coronary & Vascular Cases Symposium$600.00 o Physician, Non-Member of SCAI or ISIC$400.00 o Physician, Member of SCAI or ISIC$400.00 o Industry Professional$200.00 o Nurse, Tech, Mount Sinai Affiliates o Yes, I will also be attending the Cardiovascular Nurse Technologist Symposium, Wednesday, June 13 (included when paying full registration)

As a Full-Registration participant, PLEASE CHOOSE THE COURSE TRACK you will attend Friday, June 15: o Coronary o Vascular (Note: You may change your course track on-site, based on space availability.)

One-Day Vascular Symposium Registration (Attendance at Friday, June 15 ONLY)$300.00 o Physician, Non-Member of SCAI or ISIC$200.00 o Physician, Member of SCAI or ISIC$200.00 o Industry Professional$100.00 o Nurse, Tech, Mount Sinai Affiliates

One-Day Cardiovascular Nurse/Technologist Symposium (Wednesday, June 13 ONLY)$75.00 o Nurse, Tech, Mount Sinai Affiliate, Industry Professional

Industry Supported Workshop (Complimentary when paying Full-Registration)Will you be attending the following Wednesday Evening Industry Workshop: (Wednesday, June 13 – Sheraton NY Hotel & Towers)

Complex Cardiovascular Topics • 7:00 p.m. to 9:30 p.m. o YES o NO

Saturday Workshops (to be held at the Sheraton NY Hotel & Towers – Saturday, June 16)Will you be attending either of the Saturday Workshops:

Interventional Board Review Course • 8:00 a.m. to 12:00 p.m. o YES o NO

India Breakout Session • 1:00 p.m. to 5:00 p.m. o YES o NO

Gala EventWill you attend the Thursday Evening Gala Cruise around Manhattan? (Complimentary with Full Registration) o YES o NO

Will you be bringing a guest? ($50.00 Additional fee per guest) o YES o NO Number of guests: ______

METHOD OF PAYMENTo Check (made payable to The Page and William Black Post-Graduate School of Medicine). Amount: $__________________________________________________________

o Credit Card: o VISA o MasterCard o American Express

Credit Card Number: _______________________________________________________________Expiration Date: ________________________________

Name as it appears on credit card: _____________________________________________________Signature: _____________________________________

Office Use Only: Check No.: ________________________________________________________ Amount: $___________ Date: ___________________

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Registration Information Registration Form

FELLOWS FEES WAIVED!In order to receive the Complimentary Fellows

Full-Meeting Registration, please contact Kate Maxwell at kate@gaffneyevents.com

to obtain a fellows registration form. Complimentary registration is limited and

on a first-come, first-served basis.

REGISTER ONLINE AT:www.cccsymposium.org

• View high quality video highlights from the 2011 Symposium including lectures and case demonstrations • Join user discussion forums • View live cases via Live Webcasts

VISIT US AT OUR WEBSITE WHERE YOU WILL BE ABLE TO:

To register for the 2012 Live Symposium of Complex Coronary & Vascular Cases Complete this form and return to Gaffney Events

Gaffney Events27322 NE 143rd Pl.Duvall, WA 98019PH: 425.844.9019FAX: 425.788.0668

JUNE 13-16, 2012New York, New York

Register by May 25thand save up to $150

15TH ANNUAL

COMPLEXCORONARY & VASCULARCASES

www.cccsymposium.org

15321 Main Street NEP.O. Box 219Duvall, WA 98019