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Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: [email protected]

Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: [email protected]@definiens.com

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Page 1: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Knowledge and image processing algorithms for

real-life applications. Dr. Maria Athelogou

Principal Scientist & Scientific Liaison Manager

Email: [email protected]

Page 2: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Artificial intelligence (AI) is the technology and a branch of computer science that studies and develops intelligent machines and software. 

Goals

Knowledge Based Systems

Speech Recognition

Pattern Recognition and Pattern Analysis / Image Analysis

Robotics

Tools

Search and Optimization

Planning

Logic

Probabilistic Methods

Classifiers and statistical Learning

Neural Networks

Control theory

Languages

Page 3: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Knowledge Based Image Analysis

A Knowledge-based system is a computer program  that reasons and uses knowledge to solve complex problems.

Image analysis is the extraction of meaningful information from images; mainly from digital images by means of digital image processing techniques.

Problem:Many powerful programs and many different program libraries have been developed. In such libraries the individual programs are integrated from a low level point of view. But not support is provided to users who need to solve practical image processing problems. Every end – user cannot have a deep understanding of program semantic and syntax.

Knowledge Based Image Analysis: Experts create systems, which canuse knowledge to compose complex image analysis processes from primitive image processing operators. These systems have a Graphical User Interface, which enables the users to use the systems in order to solve image analysis tasks.

Example: GNORASI

Page 4: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Segmentation – Classificationfor Image Analysis

Segmentation:  the partitioning of a digital image into two or more regions

Classification:  analyzes the numerical properties of various image features and organizes data into categories (Classes).

Page 5: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Segmentation

Page 6: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Image

Page 7: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Segmentation Algorithm

Page 8: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Segmentation

Page 9: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Image Features

Page 10: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Classification (knowledge: Nuclei are blue and Cells are brown)

Page 11: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Classification

Page 12: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Automated Image Analysis and Quantification

The Cognition Network Technology emulates the way the human mind understands images

Definiens Cognition Network Technology® examines pixels in context to extract intelligence from images.

Multiscale

Object based

Context based

Knowledge driven

Find all relevant objects and their mutual relations create a hierarchical linked object structure referred to as „segmentation“

Link these objects with the knowledge about them and their relations knowledge representation

hierarchical classification

In the context of this technology (CNT) Image Analysis is an Iterative process:

Alternation between Segmentation and Classification

Page 13: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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CNT - Image analysis system has a GUI

This GUI contains this CNT - meta language that allows for fast and efficient development of rule bases

A rule base addresses the solution of a specific image analysis task

A rule base is reusable

Cognition Network Language is a meta language for Image Analysis

Page 14: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Operating on this network: “localized” decision making can account for biological heterogeneity

A lot of relational and often decisive context information is accessible: deeper insights, more data.

Pixels are grouped into meaningful objects……which have defined

relationships to neighbours, across the same scale

relationships to bigger or smaller objects

Morphology/Geometry/ArchitectureIntensity

Creating a network of image objects2D/2D plus time/3D/3D plus time

Page 15: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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A lot of relational and often decisive context information is accessible: deeper insights, more data.

Semantic Network

Class Hierarchy

Process Network

Algorithms HierarchyImage Object Network

Definiens Cognition Network Technology

Cognition Network Language

Page 16: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Semantic Network

Class HierarchyImage Object Network

Process Network

Algorithms Hierarchy

Definiens Cognition Network Technology

Cognition Network Language

Page 17: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Context – Objects - Features

Page 18: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Semantic Network-Class HierarchyClass definition using Fuzzy Logic

Page 19: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Slide - 20 Confidentialwww.definiens.com

Real Space / Size of Objects

1nm

1mm

1mm

10

100

10 100

0.1

10 1001m

10

100 1Km

10

Atom

transistor OrganPerson

Ship

CarHouse CityCell

Forest

m=meter

Traveling through the DimensionsReal World Applications

www.eCognition.com

Wide range of scientific areaswhich can make use of CNT

Page 20: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Slide - 21 Confidentialwww.definiens.com

Real Space / Size of Objects

1nm

1mm

1mm

10

100

10 100

0.1

10 1001m

10

100 1Km

10

Atom

transistor OrganPerson

Ship

CarHouse CityCell

Forest

m=meter

www.eCognition.com

One Technology – Many ApplicationsAutomatic Detection of Image Contents

Page 21: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Electron Microscopy

TissueHigh Content Sreening

CellsCancer Biomarker

TissueProliferation index

Tissue

3D-Confocal Microscopy

Cell biology3D-Confocal Microscopy

Tissue Molecular Pathology

3D PET/CT

Small animal

One Technology – Many ApplicationsAutomatic Detection of Image Contents

Page 22: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Page 23: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Slide - 24 Confidentialwww.definiens.comwww.definiens.com

Real Space / Size of Objects

1nm

1mm

1mm

10

100

10 100

0.1

10 1001m

10

100 1Km

10

Atom

transistor OrganPerson

Ship

CarHouse CityCell

Forest

m=meter

One Technology – Many ApplicationsAutomatic Detection of Image Contents

Page 24: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Slide - 25 Confidentialwww.definiens.com

BiopsyTissue

One Technology – Many ApplicationsAutomatic Detection of Image Contents

SerumCells

X-RayMammography

CTLiver tumor

CTBlood vessels

CTHead/Neck

MRIVentricles

CTLymph Nodes

Page 25: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Page 26: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

Slide - 27 Confidentialwww.definiens.comwww.definiens.com

Real Space / Size of Objects

1nm

1mm

1mm

10

100

10 100

0.1

10 1001m

10

100 1Km

10

Atom

transistor OrganPerson

Ship

CarHouse CityCell

Forest

m=meter

One Technology – Many ApplicationsAutomatic Detection of Image Contents

Page 27: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Geo: Impervious Surface Maps Generation www.eCognition.com

Page 28: Knowledge and image processing algorithms for real-life applications. Dr. Maria Athelogou Principal Scientist & Scientific Liaison Manager Email: mathelogou@definiens.commathelogou@definiens.com

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Thank You for Your Attention