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RICHMOND HILL - An MX-5 like never before, the new 2017 MX-5 RF (retractable fastback) stunned the world with its revolutionary and breathtak- ing design when it debuted at the New York International Auto Show earlier this year. With a new fastback-style retractable hardtop, the MX-5 RF brings a new level of sophistication and open-air appeal to the best-selling roadster of all time. Now, this car is set to take roadster fans on a new chapter, with the opportunity to pre-order one of the first cars inCanada starting today. Mazda Canada will invite a select group of loyal Mazda customers to secure their order by sending them a unique PIN code via email. This special code will give them access to the pre-order website and allow them to build and order their own MX-5 RF to their unique specifications, one week before the pre- order site opens up to the general public. "With the new MX-5 retractable fastback, we want to bring the joy of open-top driving to even more people; those people who value the security and design of a fixed-top coupe, but still want the opportunity to drive with the wind in their hair," said Vincent Reboul, Director, Marketing, Mazda Canada. "This exclusive pre-order offer will allow fifty Canadians to be among the first in the world to share in the excitement of this brand new version of the MX-5." When the MX-5 RF arrives in show- rooms, it will be available in two trim levels; GS and GT, with several option packages available to allow consumers to personalize their MX-5. CREA Housing Forecast: Sales activity to rise by 6.0% to 535,900 units DIVYA KHOSLA KUMAR WALUSCHA D`SOUZA RADHIKA APTE JACQUELINE FERNANDEZ KATRINA KAIF PICS: IANS POONAM SINHA DURING THE BOOK LAUNCH OF MOJOSH EARTH ANGELS IN MUMBAI (IANS). 2017 Mazda MX-5 RF designed for the stylish PROP UP IMMUNE SYSTEM TO PREVENT CANCER NEW YORK, (IANS) Greater emphasis on immune system- based prevention should be central to new efforts to prevent cancer, researchers say. "The body's immune system is ca- pable of intercepting pre-malignancies and preventing cancer. It does so countless times every day in all of us. That natural ability is what we want to leverage," said Elizabeth M. Jaffee from the Johns Hopkins University in the US. "Building upon our innate defenses against cancer is the foun- dation of new immunotherapies, which have shown great prom- ise in a very short time," Jaffee added. New research tools and other developments now make it possible to decipher in detail how different cancers begin, how benign or precancerous tis- sues turn malignant and deadly, the researchers said. However, "if we are ever to eradicate this scourge, we must work to prevent it from occurring altogether," noted Scott M. Lippman, Director of Moores Cancer Center at the University of California - San Diego. Prevention research has made strides, but progress has been anecdotal and isolated. OTTAWA - The Canadian Real Estate Association (Crea) has updated its forecast for home sales activity via the Multiple Listing Service® (MLS®) Systems of Canadian real estate Boards and Associations in 2016 and 2017. Canadian housing market trends have largely evolved in line with previous expectations over the second quarter of 2016, with the exception of sales activity in British Columbia and Ontario. Sales in the Lower Mainland of British Columbia have braked more abruptly than anticipated, reflecting buyer uncertainty following the introduction of the new property transfer tax on Metro Vancouver home purchases by foreign buyers. By comparison, transactions in Ontario have held steady in recent months near record levels and have yet to show signs of cooling. Taking these factors into consideration, sales forecasts have been revised upward for Ontario and downward for British Columbia. These revisions largely offset each other at the national level. In addition, Alberta's sales forecast has been revised upward, re- flecting better than expected activity during the second quarter and decent sales momentum entering the third quarter. Even so, the cur- rent economic climate suggests Alberta sales may struggle to main- tain traction over the remainder of 2016 and into 2017. Nationally, sales activity is forecast to rise by 6.0 per cent to 535,900 units in 2016, which is little changed from Crea's previously predicted sales increase of 6.1 per cent to 536,400 units this year. This represents a new record for annual sales. However, after adjust- ing for population growth, sales are still expected to remain be- low the peak reached in 2007. Among the most populous provinces, British Columbia is still fore- cast to post the largest annual increase in activity this year (+14.6 per cent) notwithstanding that much of its strength is in the rear- view mirror at this point. Prince Edward Island is forecast to post the largest annual percentage increase in sales this year (+20.1 per cent). This would make it one of only four provinces to set a new annual sales record in 2016, along with British Columbia, Manitoba and Ontario.

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RICHMOND HILL - An MX-5 like never before, the new 2017 MX-5 RF(retractable fastback) stunned the world with its revolutionary and breathtak-ing design when it debuted at the New York International Auto Show earlierthis year. With a new fastback-style retractable hardtop, the MX-5 RF bringsa new level of sophistication and open-air appeal to the best-selling roadsterof all time. Now, this car is set to take roadster fans on a new chapter, with theopportunity to pre-order one of the first cars inCanada starting today. MazdaCanada will invite a select group of loyal Mazda customers to secure theirorder by sending them a unique PIN code via email. This special code willgive them access to the pre-order website and allow them to build and ordertheir own MX-5 RF to their unique specifications, one week before the pre-order site opens up to the general public. "With the new MX-5 retractablefastback, we want to bring the joy of open-top driving to even more people;those people who value the security and design of a fixed-top coupe, but stillwant the opportunity to drive with the wind in their hair," said Vincent Reboul,Director, Marketing, Mazda Canada. "This exclusive pre-order offer will allowfifty Canadians to be among the first in the world to share in the excitement ofthis brand new version of the MX-5." When the MX-5 RF arrives in show-rooms, it will be available in two trim levels; GS and GT, with several optionpackages available to allow consumers to personalize their MX-5.

CREA Housing Forecast: Sales activityto rise by 6.0% to 535,900 units

DIVYA KHOSLA KUMAR WALUSCHA D`SOUZARADHIKA APTEJACQUELINE FERNANDEZ KATRINA KAIF PICS: IANS

POONAM SINHA DURING THE BOOK LAUNCH OF MOJOSH EARTH ANGELS IN MUMBAI (IANS).

2017 Mazda MX-5 RFdesigned for the stylish

PROP UP IMMUNE SYSTEMTO PREVENT CANCERNEW YORK, (IANS) Greater emphasis on immune system-based prevention should be central to new effor ts to preventcancer, researchers say. "The body's immune system is ca-pable of intercepting pre-malignancies and preventing cancer.It does so countless times every day in all of us. That naturalability is what we want to leverage," said Elizabeth M. Jaffeefrom the Johns Hopkins University in the US."Building upon our innate defenses against cancer is the foun-dation of new immunotherapies, which have shown great prom-ise in a very shor t time," Jaffee added. New research tools andother developments now make it possible to decipher in detailhow different cancers begin, how benign or precancerous tis-sues turn malignant and deadly, the researchers said.However, "if we are ever to eradicate this scourge, we mustwork to prevent it from occurring altogether," noted Scott M.Lippman, Director of Moores Cancer Center at the University ofCalifornia - San Diego. Prevention research has made strides,but progress has been anecdotal and isolated.

OTTAWA - The Canadian Real Estate Association (Crea) has updatedits forecast for home sales activity via the Multiple Listing Service®(MLS®) Systems of Canadian real estate Boards and Associations in2016 and 2017. Canadian housing market trends have largely evolvedin line with previous expectations over the second quar ter of 2016,with the exception of sales activity in British Columbia and Ontario.Sales in the Lower Mainland of British Columbia have braked moreabruptly than anticipated, reflecting buyer uncer tainty following theintroduction of the new proper ty transfer tax on Metro Vancouver homepurchases by foreign buyers. By comparison, transactions in Ontariohave held steady in recent months near record levels and have yet toshow signs of cooling. Taking these factors into consideration, salesforecasts have been revised upward for Ontario and downward forBritish Columbia. These revisions largely offset each other at thenational level.In addition, Alber ta's sales forecast has been revised upward, re-flecting better than expected activity during the second quar ter and

decent sales momentum entering the third quar ter. Even so, the cur-rent economic climate suggests Alber ta sales may struggle to main-tain traction over the remainder of 2016 and into 2017. Nationally,sales activity is forecast to rise by 6.0 per cent to 535,900 units in2016, which is little changed from Crea's previously predictedsales increase of 6.1 per cent to 536,400 units this year. Thisrepresents a new record for annual sales. However, af ter adjust-ing for population growth, sales are still expected to remain be-low the peak reached in 2007.Among the most populous provinces, British Columbia is still fore-cast to post the largest annual increase in activity this year (+14.6per cent) notwithstanding that much of its strength is in the rear-view mirror at this point. Prince Edward Island is forecast to postthe largest annual percentage increase in sales this year (+20.1per cent). This would make it one of only four provinces to set a newannual sales record in 2016, along with British Columbia, Manitobaand Ontario.

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Astrology tips before tying the knot

LUXURY VEHICLES: AUDI, BMW, MERCEDES, SPORTS CARS ANDCONVERTIBLE CARS. WE ALSO HAVE 7, 8, AND 9 PASSENGERS VEHICLES

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NEW DELHI, (IANS) Understanding each other is essential for a success-ful wedding. Try a few astro-numerological ways to find your soulmate,says an expert. Astro-numerologist Gauravv Mittal suggests how:* Destiny numerological card compatibility: Destiny number describesyour life purpose, your mission, and shows what you should do. Bothopportunities and internal resources come from this number, this is anarea of life that one wants to explore, develop and adopt in order to makeone's soul comfortable in life.* Name number: It reveals your inherent talents and abilities and showsthe best career path on which you will be able to use all your possibilitiesand support each other.* Personality number: It points to the vital function of its owner. Thisnumber vibrations are felt throughout the whole life. If its value is thesame for couples, they remain the most idle couple.* Birthday number: It reveals your special talent. Bir thday number espe-cially influences the mid-phase of life. Life remains cool if there is har-

mony between you and your soul number of your partner.* Soul number: To find soul number, you need only the calendar day ofyour bir th. If this number is two-digit year you need to reduce it to singledigit by adding together figures that make up this number. The higher thevalue, the stronger its vibrations are. This number indicates the hiddeninternal talent of its owner.* Soul urge number: Soul urges are able to help you to find the explana-tion for all your inner desires, dreams, hopes, to realise why you experi-ence internal motivation and where your most passionate desires arefrom. It is very important for every person to live in accordance with hisor her true desires and aspirations. Soul urge vibrations number can befound by adding the values of all the vowels of your full name.* Quiescent self: It reflects all your inner strength and hidden possibilities aboutwhich you probably don't even know. Your inner strength, the source of which isthis number, helps you to achieve the goals. Number of vibrations of quiescent selfis found by adding together the values of all the consonants of your full name.

PROLONGED SITTING CAUSES 4 PERCENT OF DEATHS WORLDWIDE: STUDY

NEW YORK, (IANS) Nearlyfour per cent of all deaths -approximately 433,000 peryear -- are due to the fact thatpeople worldwide spend morethan three hours a day justsitting down, a study has

found. Various studies overthe last decade havedemonstrated how theexcessive amount of timewe spend sitting down mayincrease the risk of death,regardless of whether or not

we exercise.The new study, published inthe American Journal ofPreventive Medicine, nowestimates the propor tion ofdeaths attributable to that'chair effect' in the population

of 54 countries, using datafrom 2002 to 2011. "It isimpor tant to minimisesedentary behaviour in orderto prevent premature deathsaround the world," said leadauthor of the study LeandroRezende from University ofSao Paulo in Brazil.He also highlighted that"cutting down on the amountof time we sit could increaselife expectancy by 0.20 yearsin the countries analysed."The results revealed that over60 per cent of people world-wide spend more than threehours a day sitting down - theaverage in adults is 4.7 hours/day -- and this is the culpritbehind 3.8 per cent of deaths.Among the territories studied,there were more deaths in theregions of the Western Pacific,followed by European coun-tries, the Eastern Mediterra-nean, America and SoutheastAsia. The highest rates werefound in Lebanon (11.6 percent), the Netherlands (7.6 percent) and Denmark (6.9 percent), while the lowest rateswere in Mexico (0.6 per cent),Myanmar (1.3 per cent) andBhutan (1.6 per cent).

Smoking impact on DNAeven 30 years after quittingNEW YORK, (IANS) Smoking, a leading preventable causeof deaths worldwide, impacts the human DNA for morethan 30 years even after one quits, a study has found. Thefindings showed that smoking leaves its "footprint" on thehuman genome in the form of DNA methylation -- a pro-cess by which cells control gene activity.Methylation, one of the mechanisms of the regulation ofgene expression, affects what genes are turned on, whichhas implications for the development of smoking-relateddiseases. "Our study has found compelling evidence thatsmoking has a long-lasting impact on our molecular ma-chinery, an impact that can last more than 30 years," saidlead author Roby Joehanes, instructor at Harvard MedicalSchool in Massachusetts, US.For people who stopped smoking, the majority of DNAmethylation sites returned to the levels that are seen inthose who never smoked within five years of quitting it.However, some DNA methylation sites persisted even af-ter 30 years of quitting. Even decades after stopping, formersmokers are at long-term risk of developing diseases in-cluding cancers, chronic obstructive pulmonary disease,and stroke.The most statistically significant methylation sites werelinked to genes enriched for association with numerousdiseases caused by cigarette smoking, such as cardio-vascular diseases and cer tain cancers. DNA methylationcould be an impor tant sign that reveals an individual'ssmoking history, and could provide researchers with po-tential targets for new therapies, the researchers said.

Activity trackers not reliablefor weight lossNEW YORK, (IANS) Wearable devices that monitor physi-cal activity are not reliable tools for weight loss, a newstudy has found. The study specifically investigatedwhether regular use of commercially available activitytrackers is effective for producing and sustaining weightloss.The study followed 470 individuals between the ages of18 and 35 with a body mass index between 25 and 39 atthe star t of the trial. Approximately 77 per cent of par-ticipants were women and 29 per cent were from mi-nority communities. According to the study, publishedin the journal JAMA, all par ticipants were placed onlow-calor ie diets, prescribed increases in physicalactivity, and received group counselling sessions onhealth and nutrition.They par ticipated in weekly health counsell ing ses-sions for the initial six months and less frequent coun-selling for the last 18 months. Weight was assessed atsix-month intervals throughout the 24-month trial. Atthe conclusion of a 24-month trial, researchers ob-served that par ticipants without physical activity track-ers showed nearly twice the weight loss benefits at theend of the 24 months.Par ticipants who uti l ised wearable devices repor tedan average weight loss of 7.7 pounds, while those whotook par t only in health counselling repor ted an aver-age loss of 13 pounds. Through these observations,researchers concluded that devices that monitor andprovide feedback on physical activity do not offer anadvantage over standard weight loss approaches thatinclude behavioural counsell ing on physical activityand diet. "While usage of wearable devices is cur-rently a popular method to track physical activity --steps taken per day or calories burned during a work-out -- our findings show that adding them to behaviouralcounselling weight loss that includes physical activityand reduced calorie intake does not improve weightloss or phys ica l ac t iv i ty engagement , " sa id JohnJakicic, researcher at the University of Pittsburgh, US.

28 MidWeek MIDWEEK NEWS WEEKLY

TUESDAY, SEPTEMBER 27, 2016r e a l e s t a t e

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SIBLINGS' MENTAL HEALTHPROBLEMS MAY AFFECT YOU

LONDON, (IANS) Individuals whohave a brother or sister with men-tal disorders may be at an in-creased risk of developing thecondition, a study has warned.The study found that having a sib-ling with schizophrenia increasesa person's risk of developing thecondition by ten times. They alsohave six to eight times increasedchance of suffer ing fromschizoaffective disorder -- symp-toms of both schizophrenia and amood disorder -- and seven to 20times greater risk of sufferingfrom bipolar disorder than thegeneral population.If a brother or sister suffers frombipolar disorder, then their sib-l ings have four t imes greaterchance of suffering from bipolardisorder, schizophrenia, and otherpsychiatric disorders. "This is alarge study which allows us toput meaningful figures on therisks of developing mental disor-

ders after they have arisen in abrother or sister," said lead re-searcher Mark Weiser, Professorat the Tel Aviv University in Is-rael. These results are importantcl in ical ly, as they encouragemental heal th workers to beaware of the increased risk ofpsychiatric disorders in siblingsof patients, the researchers said."The study can also be used byscientists studying the geneticunderpinnings of mental disor-ders, as they indicate that thesame genes might be associated

with increased risk for variouspsychiatric disorders," Weisernoted. In the study, the team ex-amined the rates of mental disor-ders in the families of 6,111 Is-rael i pat ients who had beenhospitalised with schizophrenia,bipolar disorder, or depression.They compared them to over74,000 controls, age and gendermatched controls. The findingswere presented at the EuropeanCollege of Neuropsychopharmacology (ECNP) con-gress in Vienna, recently.

Wrestler Sakshi Malik and actress Sonakshi Sinha during a programme in Mumbai (IANS).

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Shreyas Talpade and Manjari Fadnis promoting their film Wah Taj at International Institute of Fashion Designing (INFD) in Nagpur (IANS).

Eating eggs, peanuts early mayward off food allergies in babies

NICOTINE SANS TOBACCOMAY WARD OFF ALZHEIMER'SDISEASE: STUDYNEW YORK, (IANS) Nicotine -- when given independent oftobacco -- could help protect the brain as it ages and evenward off neuro-degenerative diseases such as Parkinson'sor Alzheimer's disease, US researchers have said. Theability of nicotine -- an impor tant component of cigarettes-- to be neuro-protective may be par tly due to its well-known ability to suppress appetite, said Ursula Winzer-Serhan, Associate Professor at the Texas A&M Universityin the US, in a paper published in the Journal of Toxicology.In the study, researchers added nicotine to drinking water of threedifferent groups of mice and at three different concentrations(low, medium and high) corresponding to occasional, low andmedium smokers, respectively, in comparison to a control groupthat did not receive any nicotine. The two groups that receivednicotine at low and medium doses did not show any levels of thedrug in their blood and experienced no changes in food intake,body weight or number of receptors in the brain where nicotineacts. Conversely, the group that received the highest concentra-tion of nicotine ate less, gained less weight and had more recep-tors, indicating that at higher doses, the drug gets into the brainwhere it can impact behaviour. But, even at high doses, itdidn't seem to have worrying behavioural side effects likemaking the individuals more anxious, study said.

Loneliness may run in familiesNEW YORK, (IANS) Loneliness is linked to poor physicaland mental health, and a new study of more than 10,000people has found that the risk for feeling lonely is at leastpar tially due to genetics. Genetic risk for loneliness isalso associated with neuroticism -- long-term negativeemotional state -- and depressive symptoms, said the studypublished in the journal Neuropsychopharmacology."For two people with the same number of close friends and fam-ily, one might see their social structure as adequate while theother doesn't," said lead researcher Abraham Palmer, Professorof Psychiatry at University of California - San Diego School ofMedicine in the US. "And that's what we mean by 'genetic predis-position to loneliness' -- we want to know why, genetically speak-ing, one person is more likely than another to feel lonely, even inthe same situation," Palmer noted. In their latest research, Palmerand his team examined genetic and health information from 10,760people aged 50 years and older that was collected by the Healthand Retirement Study, a longitudinal study of health, retirementand aging sponsored by the National Institute on Aging at the USNational Institutes of Health.The researchers found that loneliness, the tendency to feel lonelyover a lifetime, rather than just occasionally due to circumstance,is a modestly heritable trait -- 14 to 27 per cent. The researchersalso determined that loneliness tends to be co-inherited withneuroticism and a scale of depressive symptoms.

LONDON, (IANS) Introducing eggs and peanuts intochildren's diet early and at a young age may reduce their riskof developing food allergy, a new study has found. Allergiesto foods -- like nuts, egg, milk or wheat -- are caused by themalfunctioning and over-reacting of the immune systemtriggering symptoms of rashes, swelling, vomiting andwheezing.The study showed that children who star ted eating eggbetween the ages of four and six months had a 40 per centreduced risk of egg allergy compared to children who triedegg later in life. Children who ate peanuts between the agesof four and eleven months had a 70 per cent reduced peanutallergy risk compared to children who ate the food later.Fur ther, the researchers also found that where 5.4 per cent ofpeople with egg allergy was introduced to egg between fourand six months of age, 24 cases per 1,000 people werereduced. For peanuts, with 2.5 per cent of people the intro-duction to the food between four and eleven months, 18

cases reduced per 1,000.Until now parents were advised to delay giving allergenic foodssuch as egg, peanut, fish and wheat to their infant. However,"this new analysis pools all existing data, and suggests intro-ducing egg and peanut at an early age may prevent the develop-ment of two of the most common allergies," said lead AuthorRober t Boyle, at Imperial College London.In addition, the team analysed milk, fish (including shellfish),tree nuts - almonds - and wheat, but did not find enoughevidence to show introducing these foods at a young agereduces allergy risk. The researchers cautioned againstintroducing egg and peanut to a baby who already has a foodallergy, or has another allergic condition such as eczema."If your child falls into these categories, talk to your doctorbefore introducing these foods," Boyle said. Moreover, Boylealso noted that whole nuts should not be given to babies ortoddlers due to choking hazard, "If you decide to feed peanut toyour baby, give it as smooth peanut butter," he said.

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RITEISH DESHMUKH, NARGIS FAKHRI AND PRODUCER KRISHIKA LULLA DURING A PRESS CONFRENCE TO PROMOTE THEIRFILM BANJO IN NEW DELHI (IANS).

Epileptics face higher risks of discrimination

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COMMON CHEMICALS MAYREDUCE VITAMIN D LEVELSNEW YORK, (IANS) Exposure to cer tain common chemicalscalled endocrine-disrupting chemicals found in several con-sumer products, including plastic bottles, may reduce levelsof vitamin D in the bloodstream, says a study. Endocrine-disrupting chemicals (EDC) are found in everyday productsand throughout the environment. Bisphenol A (BPA), a knownEDC, is often found in plastics and other consumer products."Nearly every person on the planet is exposed to BPA andanother class of endocrine-disrupting chemicals called ph-thalates, so the possibility that these chemicals may evenslightly reduce vitamin D levels has widespread implica-tions for public health," said the study's first author LaurenJohns from the University of Michigan School of Public Healthin Ann Arbor. EDCs are chemicals or mixtures of chemicalsthat can cause adverse health effects by interfering with hor-mones in the body. "Vitamin D plays a broad role in maintain-ing bone and muscle health. In addition, low vitamin D levelshave been implicated in outcomes of numerous conditionssuch as cardiovascular disease, diabetes and cancer," Johnssaid. The study examined data from 4,667 US adults whopar ticipated in the National Health and Nutrition ExaminationSurvey (NHANES) between 2005 and 2010.

Binge eating may up varioushealth conditionsNEW YORK, (IANS) Individuals with binge-eating disorder(BED) may be at high risk of getting diagnosed with illnessesassociated with the endocrine and circulatory systems, astudy suggests. Binge-eating disorder is a serious eating dis-order in which an individual frequently consumes unusuallylarge amounts of food and is unable to stop craving for more.Individuals with BED could be at an increased risk of 2.5-times ofhaving an endocrine disorder and at 1.9-times of having a circulatorysystem disorder. The endocrine system influences heart, bones andtissues growth, and even fertility. It plays a vital role in determiningwhether there were chances of developing diabetes, thyroiddisease, growth disorders, sexual dysfunction, and a host ofother hormone-related disorders.

LONDON, (IANS) Researchers, including one of Indian-origin, havefound that people with epilepsy are at significantly higher risk of ex-periencing discrimination due to health problems than the generalpopulation. This risk is greater for them than those with other chronichealth problems such as diabetes, asthma and migraines. People withepilepsy also had a greater likelihood of experiencing domestic violence andsexual abuse than the general population, according to the study published in thejournal Epilepsia. The analysis also found that such psychosocial adversitiescould help explain why individuals with epilepsy are at an increased risk of devel-oping depression and anxiety disorders. "We still don't know enough aboutwhy people with epilepsy develop depression and anxiety disordersmuch more often than the general population. Our findings suggestthat adverse life events such as discrimination may be impor tant,"said senior author Dheeraj Rai from University of Bristol in Britain.

For the study, the researchers used data from the the Adult Psychiat-ric Morbidity Survey 2007 that included comprehensive interviewswith 7,403 individuals living in private residences in England. Doctor-diagnosed epilepsy and other chronic conditions were established byself-repor t. Discrimination, domestic violence, physical and sexualabuse, and other stressful life events were assessed using comput-erised self-completion and a face-to-face interview, respectively. Theresearchers found that people with epilepsy were sevenfold morelikely to have repor ted experiencing discrimination due to health prob-lems than the general population without epilepsy. "This paper dem-onstrates that despite all of the advances made over the last 100years, the experience of discrimination continues to be a significantproblem for people with epilepsy," first author of the study VictoriaNimmo-Smith from University of Bristol said.

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Strawberry flavour increasestoxicity in e-cigarettes

NEW YORK, (IANS) Are you ad-dicted to flavoured e-cigarettes?If so, then think again before youuse them. A new study has foundthat flavouring added to electroniccigarettes, par ticularly straw-berry, impacts the toxicity of thedevices. The research also men-tioned that increasing the batteryoutput voltage of these devicessignificantly increases toxicity."This study suggests that variouscharacteristics of e-cigarettes,including any flavourings, mayinduce inhalation toxicity andtherefore, caution should be usedwith these products until morecomprehensive studies are per-formed," said Maciej Goniewicz,Assistant Professor at theRoswell Park Cancer Institute, atNew York, in the US.In this study, published in the jour-nal Tobacco Control, researchersexposed bronchial cells to aero-sol generated from several vari-able-voltage e-cigarettes and

analysed cell viability and activ-ity as well as the release of in-flammatory mediators.They evaluated six types of e-ciga-rette devices filled with liquids ofdifferent flavours -- tobacco, pinacolada, menthol , coffee andstrawberry -- at several batteryoutput voltages. Their findingssuggested that the power of thee-cigarette device, as well as theaddition of any flavourings, sig-nificantly affect the toxicity of e-cigarette aerosol, with straw-

berry being the most toxic to us-ers."Our study demonstrates that e-cigarette products differ signifi-cantly in the degree of their cel-lular toxicity to bronchial epithe-l ia l cel ls," Goniewicz added.These findings have impor tantregulatory implications, becausethe features of e-cigarette prod-ucts -- such as the power of thedevice and the presence offlavourings -- can be regulatedand standardised.

SLEEP WELL AT 11 AND KICK THESUBSTANCES OUT IN YOUR TEENSNEW YORK, (IANS) Sleep duration and quality of sleep during late childhood may affect the use ofalcohol and cannabis later in adolescence years, a study has found. "Improve the amount andquality of sleep during late childhood as it would benefit in terms of reducing substance use inlater life," said Assistant Professor Brant P. Hasler from University of Pittsburgh Medical Center.For the study, researchers analysed 186 boys of low-income family and examined factors asso-ciated with vulnerability and resilience. After accounting for race, socio-economic problems,neighbourhood threat, self-regulation, and internal and external factors, both sleep duration andsleep quality at the age of 11 were associated with early substance use throughout adolescence.The study, published in the journal Drug and Alcohol Dependence, said par ticipants who slept theleast, compared to those who slept the most, were more likely to report earlier use, intoxicationand repeated use of both alcohol and cannabis. Every hour of less sleep at 11 years was associ-ated with a 20 per cent increase in the first use of alcohol and/or cannabis.While the quality of sleep though associated with alcohol use, intoxication and repeated use wasnot responsible the first use. "After considering other possible influences, we were able to deter-mine that sleep anomalies are preceding the substance use problems. Addressing sleep deficien-cies may now be something we can add into the package of our substance abuse prevention andtreatment effor ts," Hasler added.

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SHARMAN JOSHI AND SUNNY LEONE DURING THE RELEASE OF SONG TU ZAROORAT NAHI TU ZAROORI HAI FROM FILMFUDDU IN MUMBAI (IANS).

Dress right before hitting the gym

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NEW DELHI, (IANS) Always have the right pair of shoes, fresh socksand make sure you go for clothes with sweat-resistant material before you hit thegym, says an expert. Swati Deogire, Myntra Fashion Stylist, has shared importanttips on things to keep in mind before hitting the gym:* Shoes: Come prepared with a pair of basic running shoes that aresuited for a simple workout session at the gym. They will ensure thatyour feet are protected and that you stay fit as well as stay injury-free.* Hoodie: Whether you're a newbie or a fitness maniac, no workoutgear is complete without a comfor table hoodie. Invest in a sweatshir tand wear it for your workout every now and then as it will help yousweat more and lose those extra kilos faster.* Sweat resistant t-shir ts: You do need a couple of training t-shir tsbefore hitting the gym. But make sure you go for those with sweat-resistant material to avoid looking like you just took par t in a wet T-shir t contest.* Fitness tracker: The best way to stay up to date with your health isby strapping on a fitness tracker. Wear one to the gym to keep tabs onyour hear t rate, calories burned and what not!

* Fresh socks: Stock your wardrobe with at least seven sets of cottonsocks to keep you going throughout the week. They help in absorbingexcess moisture, resisting odour and also prevent blisters.* Opt for shor ts: We often overlook the simplest things in life and thesame treatment is meted out to our good 'ole gym shor ts. Go for ultra-light mesh shor ts for added comfor t. Like the T-shir ts you've investedin, ensure these too are sweat-resistant.

NEW DELHI, (IANS) From Bollywood diva Priyanka Chopra tointernational celebrities like Kerry Washington, Heidi Klumand Tracee Ellis Ros chose just a dash of skin show in cut-outdresses with a figure-hugging silhoutte for the Emmy Awards2016 red carpet. If you wish to ape the look, make sure you'reat your fittest best and opt for a single colour ensemble, In-dian designers suggest.Priyanka looked resplendent and scintillating in a scarlet JohnWu single-shoulder chiffon gown which accentuated her curvesjust at the right places. A cut-out near her svelte waist was just apt toadd a sensual look to the outfit. According to designer Varija Bajaj,the former Miss World who is now a known face in the US courtesyTV show "Quantico", "has reached that stage of her career where herpersona is much bigger than her attire"."The red gown looked splendid on her and she so gracefully carriedit. However, it is hard to imagine anyone else carrying the samecreation with the same elegance," Bajaj told IANS. The look wascarried very elegantly also by Kerry, who despite her baby bump,chose to experiment with a cut-out right below her chest, in a blackoff-shoulder gown. Heidi, on the other hand also made a bold state-ment when she stepped out in a glittering silver number which notjust gave a side-dekko at her washboard abs, but also at her perfectpins which she proudly flaunted with a thigh-high slit.Designer Pallavi Mohan of the brand Not So Serious says that suchdresses are "super chic and make their own statement. They addjust the right combination of elegance and sexiness with the subtleamount of skin show," Mohan told IANS. She also added that one has tobe fit to carry off the outfit well. "A cut-out dress will do the talks if it fitssnugly to the body, be a bodycon or a skater dress or a floor length gown.Also, unicolour cut-out dress highlights the figure, accentuating the curves,"said Mohan. Poornamrita Singh, who recently designed costumes forboth Sidharth Malhotra and Katrina Kaif in "Baar Baar Dekho", shared that"there is something very cheeky and flirty about it" which she loves. Thedesigner feels that Priyanka nailed it in her Emmys appearanceand added that "The cut-out should be in the right places foryour body type.

CUT-OUT DRESSES MAKE ACHIC CUT FOR FASHIONISTAS

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SHREYAS TALPADE AND MANJARI PHADNIS DURING THE SCREENING OF FILM WAH TAJ IN MUMBAI (IANS).

HOW DEPRESSION IS LINKED TODIABETES DURING PREGNANCY

NEW YORK, (IANS) Depression in early pregnancy more thandoubles the risk of gestational diabetes, which, in turn, increasesrisk of postpar tum depression six weeks after giving bir th, says astudy. Gestational diabetes is a form of diabetes occurring only inpregnancy and, if untreated, may cause serious health problems formother and infant."Our data suggest that depression and gestational diabetes mayoccur together," said study first author Stefanie Hinkle from USNational Institutes of Health's Eunice Kennedy Shriver NationalInstitute of Child Health and Human Development (NICHD). "Untilwe learn more, physicians may want to consider observingpregnant women with depressive symptoms for signs of gestationaldiabetes. They also may want to monitor women who have hadgestational diabetes for signs of postpar tum depression," Hinklenoted. Although obesity is known to increase the risk for gestational

diabetes, the likelihood of gestational diabetes was higher for non-obese women repor ting depression than for obese women withdepression, the study found. The researchers analysed pregnancyrecords from the NICHD Fetal Growth Studies-Singleton Cohort,which tracked the progress of thousands of pregnancies, tounderstand the patterns of fetal growth. The study enrolled 2,334non-obese and 468 obese women in weeks eight to 13 of preg-nancy.The women responded to questionnaires on symptoms of depres-sion when they enrolled in the study, again between the 16th and22nd week of pregnancy, and then six weeks after giving bir th. Theresearchers found that women who had the highest scores fordepression in the first and second trimesters -- about 17 percent --had nearly triple the risk for gestational diabetes when compared towomen who had lower depression scores.

Blind people use brainnetworks to solve math sumsNEW YORK, (IANS) Our visual experiences are not be linkedto our understanding of numbers, a study, led by an Indian-origin researcher, of people born blind has revealed. Thestudy showed that the visual cor tex -- the par t of the brainthat receives and processes sensory nerve impulses fromthe eyes -- in blind people is highly involved in numericalreasoning, suggesting that the brain is vastly more adapt-able than previously believed."The number network in brain develops totally independentlyof visual experience. Blind people have never seen anythingin their lives, but they have the same number network aspeople who can see," said lead author Shipra Kanjlia, a gradu-ate student at Johns Hopkins University in Maryland, US.Fur ther, the visual cor tex -- also known as the visual area -- involved in doing maths is similar in both blind as well assighted people, the study said.This visual cor tex is extremely plastic and, when it isn'tprocessing sight, can respond to everything from spokenlanguage to math problems. "The brain as a whole could beextremely adaptable, almost like a computer that -- depend-ing on data coming in -- could reconfigure to handle almostlimitless types of tasks," explained another researcher Ma-rina Bedny, assistant professor at Johns Hopkins University.

Internet addiction may up riskof depression, anxietyTORONTO, (IANS) Excessive use of internet may signifi-cantly increase the risk of mental health problems such asdepression and anxiety, especially among college-going stu-dents, a study has found. The findings showed that individu-als with internet addiction had more trouble dealing withtheir day-to-day activities, including life at home, at work/school and in social settings.They had problems with planning and time management,greater levels of attentional impulsivity as well as attentiondeficit hyperactivity disorder (ADHD). Internet addiction mayalso be strongly linked to compulsive behaviour and sev-eral other addiction in students, the study said."This leads us to a couple of questions like are we grosslyunderestimating the prevalence of internet addiction and arethese other mental health issues a cause or consequence ofthis excessive reliance on the internet?" said lead researcherMichael Van Ameringen from the McMaster University inCanada.The study may also have practical medical implications. "Ifyou are trying to treat someone for an addiction when in factthey are anxious or depressed, then you may be going downthe wrong route. We need to understand this more, so weneed a bigger sample, drawn from a wider, more variedpopulation," Ameringen added.

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Detoxification drinks for weight loss

Simple workout routine at officeNEW DELHI, (IANS) A sedentary lifestyle can ruin yourfitness. So, in between all the deadlines and pending work,make sure you do some stretching exercises at your work-place, suggests an exper t. Gaurav Dawar, Fitness Exper tand CEO of FlabThugs, lists down some easy workouts.Workout exercises while standing:* Try to walk around your office or walk the stairs to stretchyour legs, which is the best workout. You can also try tak-ing the widest step and lunge forward.* Raise your heels off the floor and slowly lower them. Itwill help in relaxing your calf.* Stand in front of your chair and repeat sitting down and standingup 10 times. You can do this at least three times in a day.* You can stand in front of a desk or other piece of furniturewhich is comfortable for you to hold on to for balancingyourself, lean on a sturdy piece of furniture and graduallypush your body off it in a sor t of standing push up.

NEW DELHI, (IANS) All the fluids extracted in their natural form are good fordetoxification and weight loss. And if you take the right ingredients, that mayboost weight loss. Sonia Narang, Nutrition Expert, Oriflame India, tells youhow you can drink your way to weight loss:* Banana water shake: Put one ripe banana in a blender, few ice cubes, halfcup of water. Blend till its frothy. Drink chilled. This drink is a rich source ofenergy and potassium and calcium. Good for weight loss as it doesn't havemilk which otherwise makes the drink heavy.* Coconut mint pine pina colada: Fresh coconut water, two slices of pine-apple, few leaves of mint. Blend the above in a blender. It makes for a cleandrink which is packed with minerals, good for digestion and is rich in enzymeBromelain which is known to boost weight loss. It also helps reducing badcholesterol.* Cucumber, coriander smoothie: One small cucumber, bunch of coriander,quarter ginger(grated), one spoon of aloe vera gel. Put all the above togetherin a mixer, make a smoothie, add few ice cubes and blend again. Add littlewater to have the consistency according to your taste, squeeze half a lemon

juice in this and drink. It's an amazing detoxifier. Works wonders to reduce thefat from belly. A very good diuretic to reduce the blood pressure.* Kiwi, cucumber, strawberry drink: Put cut slices of the above in a jug ofwater. The water gets infused with the goodness of these fresh fruits and vegwithin 5-10 minutes. Keep drinking through this jug and refilling with morewater. The fruity flavour of this water is refreshing and alkaline. This drinkgives the nutrients of the ingredients like Vitamin C and Vitamin A. The watercan be infused with any random fruits and vegetables that meets the eye.* Turmeric lemon detox tea: Put half teaspoon turmeric powder, few tealeaves, a pinch of cinnamon in 200 ml. Add water and bring to boil. Cool it and thenadd half a lemon's juice and drink. This tea can be had warm or ice cold. It's adetoxifier. It's a rich source of flavonoids and has the goodness and antibacterialqualities of turmeric. You can also also add 1/2 tsp honey to the same.* Green coffee coconut: Put a sachet of green coffee in a mug of hot boilingwater and let it steep for 10 minutes. Strain and add half teaspoon coldpressed extra virgin coconut oil to it and drink. This enhances metabolismand is rich in antioxidants. Coconut oil is heart and bone healthy.

VIDEO GAMES CAN BEAT TUTORS INIMPROVING MATH SKILLSNEW YORK, (IANS) A computer-based brain trainingprogramme developed at Yale University helps improvestudent per formance in reading and math -- in somecases even more than individualised tutoring, accord-ing to a new study. In a study of more than 500 secondgraders, math and reading scores on school- adminis-tered tests increased significantly more in children whoused the brain training programme Activate during theschool year than in control classes. The effect on mathachievement scores was greater than what has beenrepor ted for one-on-one tutoring, said the study pub-lished in the journal Scientific Repor ts."The programme increases focus, self-control, and memory --cognitive skills essential for learning," said lead author of the studyBruce Wexler, Professor Emeritus of Psychiatry at Yale Uni-versity in New Haven, Connecticut, US.

SONAM KAPOOR AT THE INAUGURATION OF KALYAN JEWELLERS SHOWROOM IN CHENNAI (PTI)

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