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29 - AdapthaDol This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors. AdapthaDol Dietary supplement in liquid form for bringing relief from states of nervous tension. Instructions for use. Spray directly under the tongue and the oral cavity from 5 up to a maximum of 10 times, as required during the day (equal to a maximum of 2 grams of product). Spread well around the mouth. Ingredients. Water, Echinacea roots (Echinacea angustifolia), Eleuterococcus roots (Acanthopanax senticosus), Hawthorn flowers and leaves (Crataegus oxyacantha), Pomegranate fruits (Punica granatum), Grapefruit fruits (Citrus grandis), Schisandra fruits (Schisandra chinensis), Spirae tops (Filipendula ulmaria), Rowan fruits (Sorbus aucuparia), Rhodiola roots (Rhodiola rosea), Bromeline from pineapple dry extracts (Ananas comosus) 250 GDU, Mangosteen fruits (Garcinia Mangostana), Acidifier, Citrus acid. WITHOUT PRESERVATIVES AND WITHOUT ADDED SUGARS 30ml NUTRITIONAL CONTENT OF THE PRODUCT le: liquid extract de: dry extract g per 100 grams mg per max dose Echinacea le 9,4 188 Eleuterococcus le 7,5 150 Hawthorn le 5,0 100 Pomegranate juice 4,6 92 Grapefruit juice 3,5 70 Schisandra le 2,5 50 Spirae le 1,5 30 Rowan le 1,0 20 Rhodiola de 1,0 20 Pineapple de 0,5 10 Mangosteen de 0,1 2 DENPAS S.r.l. 37047 S. Bonifacio Verona (Italy) www.denpas.it Shake before use. The presence of light sediment is an intrinsic feature of the product. It is recommended to keep within the indicated doses and not exceed them in usage. Taking dietary supplements should not be considered as a substitute for a varied diet. Do not take the product during pregnancy. Keep out of the reach of children under three years of age. Once opened, consume within 30 days. dol for bringing relief from states of nervous tension daptha adaptogen spray &

Adaptha Dol Technical ENG

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AdapthaDol Dietary supplement in liquid form for bringing relief from states of nervous tension. Instructions for use. Spray directly under the tongue and the oral cavity from 5 up to a maximum of 10 times, as required during the day (equal to a maximum of 2 grams of product). Spread well around the mouth. DENPAS S.r.l. 37047 S. Bonifacio Verona (Italy) www.denpas.it 29 - AdapthaDol NUTRITIONAL CONTENT OF THE PRODUCT g per 100 grams mg per max dose & le: liquid extract de: dry extract

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Page 1: Adaptha Dol Technical ENG

29 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

AdapthaDol Dietary supplement in liquidform for bringing relief from statesof nervous tension. Instructions for use. Spray directly underthe tongue and the oral cavity from 5 up to a maximum of 10 times, as required during the day (equal to a maximum of 2 grams of product). Spread well around the mouth. Ingredients. Water, Echinacea roots (Echinacea angustifolia), Eleuterococcus roots (Acanthopanax senticosus), Hawthorn flowers and leaves (Crataegus oxyacantha), Pomegranate fruits (Punica granatum), Grapefruit fruits (Citrus grandis), Schisandra fruits (Schisandra chinensis), Spirae tops (Filipendula ulmaria), Rowan fruits (Sorbus aucuparia), Rhodiola roots (Rhodiola rosea), Bromeline from pineapple dry extracts (Ananas comosus) 250 GDU, Mangosteen fruits (Garcinia Mangostana), Acidifier, Citrus acid.WITHOUT PRESERVATIVES AND WITHOUT ADDED SUGARS

30ml

NUTRITIONALCONTENT OFTHE PRODUCT

le: liquid extractde: dry extract

g pe

r 10

0 gr

ams

mg

per

max

dos

e

Echinacea le 9,4 188Eleuterococcus le 7,5 150Hawthorn le 5,0 100Pomegranate juice 4,6 92Grapefruit juice 3,5 70Schisandra le 2,5 50Spirae le 1,5 30Rowan le 1,0 20Rhodiola de 1,0 20Pineapple de 0,5 10Mangosteen de 0,1 2

DENPAS S.r.l. 37047 S. Bonifacio Verona (Italy)www.denpas.it

Shake before use.The presence of light sedimentis an intrinsic feature of the product.It is recommended to keep withinthe indicated doses and not exceedthem in usage. Taking dietary supplements should not be consideredas a substitute for a varied diet.Do not take the product during pregnancy. Keep out of the reachof children under three years of age.Once opened, consume within 30 days.

dolfor bringing relieffrom statesof nervous tension

dapthaadaptogen spray

&

Page 2: Adaptha Dol Technical ENG

30 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

Adaptogen spray

AdapthaDol

Adaptogens

EchinaceaEchinacea angustifolia

Family: Compositae

Synonym: rudbeckia, purple coneflower.

Part used: the roots.

Popular and herbalist tradition: Echinacea is an adaptogenic plant that improves the resistance of the organism to external attacks by stimulating the immune system. Originally from the western North American plains, Echinacea is traditionally used for its properties of stimulating the immune system. Native Americans used echinacea for its properties of purifying the blood and for the treatment of numerous conditions: infections, wounds, eczema, rheumatism, syphilis, haemorrhoids and also as a general painkiller. At the beginning of the 20th century, European and American herbalists used this plant to treat viper bits and certain infectious illnesses such as typhoid and diptheria. In the twenties, it lost popularity with the arrival of synthetic drugs, nevertheless today it is one of the most widely used remedies for reinforcing the natural defences of the organism, especially against seasonal indispositions such as colds, influenza, coughs and seasonal allergies.

Principle ingredients: polyphenic compounds derived from caffeic acid: echinacoside, chicory acid, chlorogenic acid. Essential oil: polyacetylene compounds, N-isobutylamide Polysaccharides of high molecular weight.

Activity: adaptogen with immuno-stimulant characteristics, generally indicated for problems linked to winter ailments, a tonic.

Page 3: Adaptha Dol Technical ENG

31 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

EleuterococcusAcanthopanax senticosus Maxim

Family: Araliaceae

Synonyms: Siberian ginseng, devil’s stick.

Part used: rhyzome and roots.

Popular and herbalist tradition: the botanic name of the family of eleuterococcus is “Acantopanax” where: Acanto means “thorny” - Panax means “panacea.” The modern story of this plant begins with Brekham, in the forties, who, in the course of research to find an alternative to ginseng, discovered that eleuterococcus offered many of the benefits of the very famous Chinese and Korean product. Later research by Soviet and Chinese scientists has shown that eleuterococcus is a tonic-adaptogen with peculiar characteristics often even greater than those of the Chinese root (for example, at the level of the immune system). It is still well known for its use to aid the performance of the Russian athletes at the Moscow Olympics and for cosmonauts during long periods in space. Eleuterococcus is traditionally indicated as a tonic to reinforce the body during exertions and as a remedy against debilitation and the tendency of diminished working capacity and concentration, and during convalescence. It possesses a general action of stimulating the immune system.

Principle ingredients: eleuterosides, polysaccharides, phenolic compounds (coumarins, lignans, phenilpropans).

Activity: adaptogen, anti-asthenic, anti-stress, tonic.

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32 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

HawthornCrataegus oxyacantha

Family: Rosaceae.

Synonyms: hawthorn, bossolin, spinapulce, calaringhe.

Parts used: flowers and leaves.

Popular and herbalist tradition: used in Europe since the Middle Ages, popular medicine indicates hawthorn as a sedative remedy for the Central Nervous System and it is recommended for heart and circulation disturbances. Western herbalists consider it to be “food for the heart” because it increases the flow of blood to the heart and regulates its beat. Moreover, it is present in various medicinal preparations against insomnia and nervous conditions. Hawthorn displays a recognised sedative and muscle relaxant action which makes it particularly indicated for states of stress and anxiety. It has been demonstrated that its administration brings a calming effect on the central nervous system, being especially indicated in cases of sleep disturbances and in conditions characterised by excessive emotionality and anxiety, in stress and in the menopause. It has also been confirmed that the plant contributes to the elimination of the emotional elements of certain states of hypertension. The studies carried out reveal an important action on the cardiovascular system with a real improvement in resistance to exertion.

Principle ingredients: flavonoids including hyperosid and vitexin, triterpenoid compounds including ursolic acid, amine, sterols; tannin and purine derivatives.

Activities: invigorating, antidiarrhoeal, hypotensive and cardiotonic.

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33 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

SchisandraSchisandra chinensis

Famiglia: Schisandraceae.

Synonyms: Wu Wei Zi, Schizandra japonica.

Parts used: the fruit.

Popular and herbalist tradition: It is a deciduous and evergreen climber, of great development, with scented flowers and fruit similar to berries, widespread in eastern Asia and eastern North America, and introduced in the gardens of the West around 1850. The name Schisandra derives from the Greek, skhisis, “separation, fissure” and andros, “male,” referring to the garish dehiscence of the two anther pods. The Chinese name, “Wu Wei Zi” means “plant with 5 flavours” because, according to the system of traditional Chinese medicine, this plant contains all the flavours that regulate the effects of food on the body. Representative experiments showing the adaptogen action of Schisandra were conducted in the Soviet Union with volunteers from various professions; fighter pilots, wireless operators, athletes and intellectuals. The results were extremely positive with an improvement in performance, both physical and intellectual, with greater clarity of action and greater resistance to fatigue.

Principle ingredients: active schisandrina (methyl ester of polyphenols) Adaptogen: lignans (7% to 19.2%); sugars; tannins; essential oil; organic acids (citric acid and tartaric acid); vitamins (vitamins C and E); minerals (copper, manganese); micro elements (nickel, zink, traces of titanium and silver).

Activities: detoxicant, tonic, astringent, adaptogen, stimulant, hepatoprotective antioxidant.

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34 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

RodiolaRhodiola rosea

Family: Crassulaceae.

Part used: the roots.

Synonyms: golden root.

Part used: the roots.

Popular and herbalist tradition: traditionally used in Nordic countries to increase physical resistance and immunity, and longevity of the individual, Rhodiola has an almost legendary history. In Siberia, roots are administered to couples before marriage to promote the birth of healthy children. Rhodiola, believed to be a powerful stimulant, was used in the formulation of various love potions; the Ukrainian prince, Galitsky, who lived in the 13th century, boasted of being a great lover thanks to the roots of Rhodiola. For many centuries, Chinese emperors, who used the root to treat many different disturbances and illnesses, sent expeditions to eastern Siberia in search of the area where Rhodiola grew spontaneously. The first scientific studies on Rodiola date back to the first half of the last century, when groups of Russian scientists began to observe the effects of this plant; it was only in the early years of the sixties that information about the benefits and properties of Rhodiola was made public in the western world.

Principle ingredients: glycosidic phenolic compounds (rosavin, rosin, rosarin, salidoris), organic acids (oxalic, citric, malic, succinic, gallic), monoterpenes, beta-sitosterol, essential oils, mineral salts.

Activities: adaptogen, anti-stress, useful in the control of body weight when associated with a balanced diet. Improves the concentraton, lucidity and mnemonic potential; indicated in the treatment of asthenia, depression, apathy, stress, muscular weakness and to optimise sporting performance by reducing the duration of the recovery phase.

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35 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

FRUITS

PomegranatePunica granatum

a precious concentrate of antioxidant substances (polyphenols derived from ellagic acid), organic acids, minerals (calcium, iron, magnesium, phosphorous, potassium, copper and sulphur), vitamins (robiflavin, thiamine, vitamin B6, niacin, pantothenic acid, beta-carotene). The juice of the pomegranate combines recognised antioxidant, re-mineralising and vitamin properties with a pleasurable and refreshing taste.

GrapefruitCitrus grandis

Rich in flavonoids, pectins, vitamins of group B, vitamin C, pantothenic acid and organic acids, it possesses the organoleptic and nutritional qualities of citrus fruit.

MangosteenGarcinia mangostana

Garcinia mangostana, commonly known by the name, Mangosteen, is a typical fruit from the vast area of South-East Asia, belonging to the family of the Guttifere, and widespread in countries like Thailand, India, Malaysia, Vietnam and the Philippines, but also Australia and Hawaii. The benefits of this fruit with its pleasurably acidic flavour have recently been brought to light by studies that have revealed its marked antioxidant and immuno-modulating action.

RowanSorbus aucuparia

The name “aucuparia” (from the Latin, aiucupium: fowling) derives from the fact that, the berries being much loved by small migratory birds, it was traditionally used in traps in hunting such prey. Dried service tree fruit (also called sorb or whitty pear), in the past, was mixed with flour to enrich the bread at times of scarcity. Containing derivatives of parasorbic acid which determines the natural antifungal and anti-bacterial actions.

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36 - AdapthaDol

This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

Functionalizing

Spirea UlmariaSpiraea Ulmaria

Herbalist/popular tradition: in the Middle Ages, Spirea Ulmaria was a favourite common herb. Gerard wrote in his Herball (1597) that the “odour from this source makes the heart happy and joyous and delights the senses.” The salicylic acid isolated from the plant was synthesised for the first time in 1890 and used to create aspirin. It was moreover one of the herbs most sacred to the Druids, but it is not known whether it was also used as a medicine. For a long time, it was a popular remedy in many parts of Europe. Nicholas Culpeper wrote in 1652 that “boiled in wine, it quickly helps those with the colic and stops diarrhoea.” Used for gastric problems and inflammatory pathologies like arthritis.

Activities: analgesic, antacid, anti-inflammatory, light urinary antiseptic, anti-ulcerogenic, astringent.

Neutralising action: combats gastric hyperacidity. A decoction of flowers of Dropwort (1:10; 1:20) have a demonstrated preventative activity on ulcers caused by ulcerogenic agents such as aspirins and ethanol, and reduced the ulcerogenic effect of the pylorus ligament.

Anti-inflammatory action: the phenolic glycosides such as salicin possess

the anti-inflammatory effects typical of the salicylates. The content, derived from salicylic acid and flavonoids, therefore supports the observed anti-inflammatory, analgesic, antispasmodic and antibacterial effects of the medicine. It has a remarkable action as a diuretic, favouring the retention of water and the formation of fatty accumulations.

Principle ingredients: flavonoid glucosides: quercetin, spiraosides (quercetin-4’-glucoside), kempferolo; phenolic glycosides (salicylates), salicilaldeide, polyphenols (tannins) spiraoside (quercetin-4’-glucoside).

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This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

spiraeoside (quercetin-4’-glucoside)

Essential oil: salicilaldehyde (75%), ethyl salicylate, methyl salicylate, I. methoxybenzaldehyde, etc..Phenolic glycosides: spireina, monotropina, gaultherina. II. Flavonoids: spiroside, rutin, iperoside, avicularina. III. Polyphenols: especially tannins.IV. Chalcones, Phenylcarboxylic acid, ascorbic acid.V.

Indications: ulmaria, commonly known as Meadowsweet, is one of the anti-

inflammatory and analgesic remedies most delicate on the gastric mucous and is often used in the treatment of painful inflammatory complaints such

as rheumatic pain, headaches and toothache. Also used as a depurative.

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This documentation is reserved to the professional corps. The information contained herein is based on our knowledge at the moment of going to press. The user is advised to ensure the suitability and completeness of this information in relation to the specific use that is to be made of it. The information given must not be considered a guide to self-medication. Users are invited to discuss the information with Doctors, Pharmacists or an authorised Personal Physician. Facts, studies and claims are the result of bibliographic research carried out on individual plants drugs. The editorial team is not responsible for typographical or typing errors.

PineappleAnanas Sativus

Herbalist/popular tradition: discovered by colonists of the American tropics, it was almost immediately introduced in Europe, but given the difficulties and length of early ocean crossings, it was only in 1733 that the growth of the first pineapple fruit was celebrated in old Europe. Cultivation in Italy began in Naples, then in the important greenhouse of Villa Reale of Monza, under Umberto I. From there, it spread to the greenhouses of Lombardy and Piedmont, Veneto and Tuscany.

Actions: the bromeline contained in the pineapple was the first proteolytic

protein (that is, capable of breaking down proteins) identified. This enzyme has

the capacity of breaking down in a few minutes the equivalent in protein of

1,000 times its weight. It has a vigorous anti-edematous power. The activity of bromeline in combatting the inflammatory processes has been known and studied for a long time; today, nevertheless, no unequivocal mechanism of the action is known. Various studies have shown it provides support in cases of

acute and chronic inflammation.

Principle ingredients: nitrogenous substance, citric acid, Bromeline.

Indications: edamatous manifestations, inflammatory states, auxiliary disinfiltration in the treatment of cellulite.