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    HEAD TRAUMA

    Oleh :Litany alamudi

    Pembimbing :Dr. Jovizal,Sp.S

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    Layers of the Cranial Vault

    Anatomy of the Brainwww.neurosurgery.org/pubpgages/patres/anatofbrain.html#micro

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    Definition Traumatic Brain Injury

    Traumatic brain injury (TBI) is a seriousneurodisorder commonly caused by car accidents,

    sports related events or violence

    Review molecular mechanisms in the pathogenesis of traumatic brain injuryhttp://www.hh.um.es

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    Mechanisms of Injury for TBI

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    Traumatic Brain Injury

    Primary Brain Injury

    Results from what hasoccurred to the brain at

    the time of the injury

    Secondary Brain Injury

    Physiologic andbiochemical events which

    follow the primary injury

    World journal of emergency surgerymolecular mechanisms of traumatic brain injury:the missing link in management

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    Traumatic Head Injury

    www.med.ub.es/All-Net/english/neuropage/trauma/head-8htm

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    HEAD INJURIES / BRAIN INJURIES

    Skull fractureDiffuse Axonal InjuryEpidural HematomaSubdural Hematoma

    Coup contussionContracoup contussion

    World journal of emergency surgerymolecular mechanisms of traumatic brain injury:the missing link in management

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    EPIDURALANDSUBDURALHEMATOMA

    www.med.ub.es/All-Net/english/neuropage/trauma/head-8htm

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    SUBDURALHEMATOMA

    C d C

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    Coup and ContracoupContusions

    A combination of vascular and tissue damage leadsto cerebral contusion

    Coup contusions occur at the area of direct impact

    to the skull and occur because of the creation ofnegative pressure.

    Contracoup contusions are similar to coupcontusions but are located opposite the site of

    direct impact

    World journal of emergency surgerymolecular mechanisms of traumatic brain injury:the missing link in management

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    ASSESSMENT

    Note: Monitorsecure airway and protect c-spine

    Assess breathing

    Assess circulation Control major bleeding

    Prevent hypotension

    Transport decision and interventions

    GCS

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    ASSESSMENT DETAILEDEXAM

    Vital signs SAMPLE history Head-to-toe exam, including neurological

    and GCS, fluid Continuous observation

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Management ofTraumatic Head Injury

    Maximize oxygenation and ventilation

    Support circulation / maximize cerebral

    perfusion pressure

    Decrease intracranial pressure

    Decrease cerebral metabolic rate

    Guidelines for the management of severe traumatic brain injury 3rd edition

    P i S d

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    Primary vs. SecondaryBrain Injury

    Primary injury is immediate from bruising orpenetrating objects

    Secondary injury is from hypoxia orperfusion of the brain Caused by swelling, hypoxia, or hypotension Hyperventilation decreases perfusion of the brain

    tissueProtect airway, give oxygen, maintain BP

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Intracranial Pressure (ICP)

    ICP is usually low (15mmhg was one of five

    independent risk factors associated with death.

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Lowering ICP

    Evacuate hematoma Drain CSF Intraventricular catheters use is limited by degree of

    edema

    Craniotomy Permanence, risk of infection, questionable benefit

    Reduce edema Promote venous return Reduce cerebral metabolic rate Reduce activity associated with elevated ICP

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Diuretic Therapy

    Osmotic Diuretic Mannitol (0.25-1 gm / kg) Increases osmolarity Vasoconstriction

    (adenosine)

    Loop Diuretic Furosemide Decreased CSF formation Decreased systemic and

    cerebral blood volume(impairs sodium and water

    movement across blood brainbarrier)

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Hypertonic Fluid Administration

    Hypertonic saline Comparing mannitol with barbiturates for controlICP after TBI

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Anesthetics, Analgetic and sedatives

    High dose barbiturate therapy can result in control ofICP when all others medical and surgical treatmentshave failed.

    Anticonvulsants - Prevent seizure activity

    PentobarbitalAdverse effects include hypotension and bone

    marrow dysfunction

    Used only after unsuccessful attempts to control

    ICP and maximize CPP with other therapies

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    Dose regimens

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    Factors that Effect Secondary BrainInjuries

    Blood PressureOxygenationTemperature

    Control of Blood GlucoseFluid Volume Status Increased Intracranial Pressure

    Guidelines for the management of severe traumatic brain injury 3rd edition

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    References

    Dr. Baxter Larmon, Director of the UCLA CPCand Professor of Medicine, UCLA School ofMedicine

    UCLA EMT Lectures, Barry Jensen and EMTTeam, 2003

    Brady / DOT paramedic lectures and curriculum

    www.emedicine.com

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    Evidence SupportingNormoventilation

    Forbes et al. (1998) Journal of Neurosurgery, 88(3)

    Marion et al. (1995) New Horizons, 3(3)

    McLaughlin & Marion (1996) Journal of Neurosurgery, 85(5

    Muizelaar et al. (1991) Journal of Neurosurgery, 75(5)

    Newell et al. (1996) Neurosurgery, 39(1)

    Skippen et al. (1997) Critical Care Medicine, 25(8)

    Yundt & Diringer (1997) Critical Care Clinics, 13(1)