CRC Group - Research and Project Center

Welcome to CRC Group

Various Department

Admission Open-Offer30% # Job Placement consultancy

# Projects & Training – All Biotech/Life

Science/MBA/MCA/Engg/Medical/Pharma Etc..UG/PG/Ph.D

Contact:[email protected]

CRC DIVISION• CRC Division-Chromosoft Research Centre is a growing

organization founded by Dr.MOKS with a team of young scientists with extensive academic and industrial experience in the areas of modern biology for over five years and training wide spectrum of Research scholar, Students of School, Colleges and Teachers in the field of Modern biology likePharma, Biotechnology, Bioinformatics, Molecular Biology, Microbiology, Biochemistry, Biomedical Genetiecs and Students, Faculty of Siddha, Ayurveda,Medicine etc., The objective of CRC is to provide training programs that is aimed to Narrow the gap between the Academic institutions and Industry, thereby enhancing the skill of market oriented professionals.

• To provide students pursuing Life science and related careers with good laboratory skills and technical knowledge to full fill their academic goals.

• Speciality of the work shop • Interaction with Scientists from industry and academic background • Personal support for each students throughout the programme• Sound practical training • Limited number of students for each batch • Programs are designed as per the University syllabus• Nominal fee• PROJECTS• CRC has guided more than 1500 research Work/ projects for All

UG/PG- M.Sc.,Pharmacy, M.Phil., Ph.D., B.Tech and M.Tech students on all aspects of Biotechnology, Molecular Biology, Bioinformatics, Microbiology and Biochemistry.

• COURSE MODULES• The laboratory programs are designed to provide “HANDS-ON” Experience to learn

basic and advanced techniques in Pharma,Microbiology, Biochemistry, Molecular Biology, Plant Biotechnology, Animal Biotechnology and Immunotechnology.

• MODULE 1: Fees : Rs.4000.00• Basic Molecular biology and Molecular Genetics • Venue Date:• 1. Chennai -6 Batch• 1. Isolation of DNA from bacteria. • 2. Isolation DNA from Plant• 3. Isolation of RNA from yeast. • 4. Agarose gel Electrophoresis. • 5. DNA quantification by Spectrophotometer• 6. Plasmid DNA Isolation from bacteria. • 7. DNA elution from agarose gel. • 8. SDS-PAGE• 9. Restriction enzyme Digestion• 10.PCR-RAPD

• MODULE 2: Fees : Rs.5000.00• Advanced Molecular biology Techniques• Venue Date:• 1. Chennai -5 Batch• 1. DNA Fingerprinting• 2. Protein Fingerprinting • 3. RT PCR • 4. Nested PCR• 5. Southern blotting• 6. Northern Blotting• 7. Western blotting• 8. Gene Expression• MODULE 3: Fees :3500.00• Immunotechnology• Venue Date:• 1 – Chennai -3 Batch

CRC- TRAINING COURSESMODULE 1: Basic and Clinical Microbiology Techniques1. Designing of Microbiology laboratory & Handling of instruments2. Media preparation3. Isolation of Microbes from various sources4. Characterization of Microbes using conventional and moderntechniques5. Maintenance and Transport of culture6. Phage titration assay7. Growth curve8. Bacterial conjugationDURATION – 1 week, Rs 4500MODULE 2: Mycotechnology1. Setting up of Mycology lab2. Preparation of Various culture media3. Isolation of Fungus from various environmental & clinical sample4. Identification of fungus using conventional and molecular techniques

5. Maintenance of fungal cultures6. Extraction of DNA from Fungus and characterization using AGE7. Extraction and characterization of Fungal proteins using SDSPAGEDURATION – 2 weeks Rs 6500MODULE 3: Molecular Biology and Molecular GeneticsBasic Module1. Isolation of DNA from Bacteria, Fungi, Yeast & Plant2. Isolation of RNA from Bacteria & Yeast3. Agarose gel electrophoresis4. DNA quantification using spectrophotometer5. Plasmid DNA isolation from Bacteria6. DNA elution technique7. PCR8. SDS-PAGEDURATION – 10 DAYS, Rs 3500

Advanced Module I1. DNA fingerprintingi. RFLPii. AFLPiii. RAPDiv. ERIC PCR2. Different types of PCRi. RT PCRii. Nested PCR3. Protein profilingDURATION – 1 week Rs 6000Advanced Module II1.PCR detection of SNP & PNP2.Detection of DNA contamination using PCR3.Blotting techniquesi. Southern Blottingii. Northern Blottingiii. Western Blotting4.TransformationDURATION – 1 week Rs 5000

Sophisticated Techniques*1.Detection by autoradiography using radiolabelled probes2.Transformation of DNA from prokaryotes to eukaryotes* - Enquire for detailsMODULE 4: Immunotechnology1. Immunization and Schedule (theory)2. Antigen and Antibody characterizationSingle Radial Immuno DiffusionODD patternImmunoelectrophoresisRocket ImmunoelectrophoresisCounter current Immunoelectrophoresis3. Lymphocyte Preparation4. Dot- ELISA

DURATION –1 week Rs 4000MODULE 5: Plant Tissue Culture Techniques1. Tissue Culture media preparation2. Inoculation of Stem, Leaf, Root and Stem3. Anther Culture4. Embryo Culture5. Agrobacterium Mediated Transformation6. Protoplast Isolation7. Identification of herbal plants for Anti-cancer, Anti-diabeticand Antimicrobialstudy8. Phytochemical analysis of bioactive compounds9. Detection of bioactive compounds using TLC,HPTLC & HPLC

DURATION – 1 week Rs 8000MODULE 6: Animal Tissue Culture Techniques1. Primary cell culture2. Cryopreservation & Revival of cell lines3. Maintenance of Cell lines4. Subculture and Passaging of Cell lines5. Identification of Virus – HA or HAI6. Fixing of Cells for Staining7. Determination of Cytotoxicity of Cell lines8. Screening for Antiviral and Anticancer activity of Plant Extract9. Estimation of Cytotoxicity by Biochemical Analysis (MTT assay)

DURATION – 1 week Rs 9000MODULE 7: Chromatographic Techniques1. Thin Layer (TLC) and Paper Chromatography2. Column Chromatography3. Gel Filtration chromatography4. Ion exchange Chromatography5. High Performance Thin Layer Chromatography (HPTLC)6. High Performance Liquid Chromatography (HPLC)DURATION – 7 DAYS, Rs 8000

Our People

Class Room

CRC – Group RESEARCH CENTRE

Microbiological analysis of samples with reference to bacteria, fungi, yeast, moulds & Actinomycetes

Virulence anlaysis of pathogensPCR detection of pathogens

Gene specific PCRGenetic diversity of the microbes

RAPD PCRERIC PCRRep PCRBOX PCR

16 srRNA PCR analysisSDS PAGE analysis of proteins

Western Blot analysisEnzyme profiling & all enzyme related studies

Extraction of compounds from plants & microbesBiological activity of compounds

Antibacterial activityAntifungal activity

Purification of biomolecules, proteins & enzymes Gel filtration chromatography

Ion Exchange ChromatographyAffinity Chromatography

TLC & BioautographyPlant tissue culture based works

Standardization & optimization of tissue culture plants for specific compoundsOptimization of tissue culture raised plants

Animal cell cultureCytotoxic analysis of compounds

Antitumour evalution of compoundsEvalution of Ahderence & invasiness of pathogens

REAL TIME RESEARCH TRAINING CENTRE / SEMINARS / WORKSHOP

COURSES OFFERED:

CERTIFICATE COURSES (Part / Full time)

• Bio, Chemical informatics: (1 Month program) • Pharmaco Informatics in Drug Designing / Molecular modelling

(3 Weeks Program) • Singapore University Colloboration Industrial Projects • Analytical and Clinical Research: (Apex Technical University) • Hands on training instrumentation (1 Month program) • Bio-Analysis (Pre clinical, clinical) (6Weeks program) • Pharmacokinetics (1 Month program) • Bio-Statistics (1 Month program) • Clinical Data Management (2 Month program) • Supply Chain Management (SCM) (2 Month program) • Project Management (PMP)Live

Projects: **• Analysis (Pharmaceutical and Biological) (1 Month program)

• ERP and SCM (3 Month program)

http://www.crcgroupin.com/contact.html

























STUDENT PROJECTS

• First-nopefAdmission Open

• Training-calendar-dec07-to-jun08

• Application form for students with instructions

• Application Form

• Data Mining • Database Construction • Tool Development • Post sequencing analysis of the genomic/contig

sequences (sequence assembly) • Immunoinformatics (Epitope Predictions) • Comparative Genomics • Gene Identification and Characterization • Microarray Data Analysis • Metabolomics (Pathway Analysis)

Current Research• Comparative analysis of leprosy causes type 1 & type 2 genes • Insilco characterization and analysis of RB1 gene • Identification of suitable ligand for molecular docking of pancreatic

cancer • An in-silico studies on the Interaction of Antxr1 with protective

antigen(toxin) • Identification of suitable ligand for molecular docking of Rheumatic

Heart Disease using combinatorial chemistry • Structure prediction for the protein product of SIVA1 gene-

Homology modelling approach. • Structure prediction for the 3 beta-hydroxysteroid dehydrogenase-

Homology modelling approach. • Docking studies on the binding site of receptor -BRCA1 and

screening its suitable ligands

• Bioinformatics

Services include DNA and Protein sequence Analysis, Protein Structure Analysis, Homology Modeling, Biostatistics, Data analysis using SAS/R, and Microarray data analysis.

Chemoinformatics

Services include Molecular Modeling Studies, Lead Generation, Virtual Screening, ADME and Toxicological Property Prediction and Crystal Structure Prediction. Structural Biology Structure determination services, critical analysis of protein structures, protein-drug interactions and protein-protein interactions.

• Custom curation

Provide data-mining services and annotation of chemical, biological, pharmacological and toxicity information from patents, journals or targets. Information is curated in custom-designed formats to meet specific client requirements.

- Bio-indexing- Pharma-indexing- Name to structure

Services / Medical ChemsitryOur Medicinal Chemistry services meet exacting client needs for organic / medicinal chemistry and include synthesis of: • Building Blocks, Scaffolds, Intermediate com¬pounds, Reference compounds • Specially designed small molecules or analogues for Lead Generation and Lead Optimization • Pharmacophore based focused libraries gener¬ated for a particular target protein • Compound Libraries • Lead compounds in grams and kilos (custom synthesis)

Other Services

• Pharma Machinery Dealers• Pharma Machinery Distributors• Pharma Consultancy, Students, Industry• Bio Technology/ Students, Industry• Herbal Formulation Distributors• Herbal Raw Material Distributors• Herbal Plants – Raw Material Sales• Medicinal Plants Sales/ Raw Material Distributors• Job Placement Non IT(science/Medical/Pharmacy/Bio

Informatics/Bio Technology/MBA/Top Management)• Health Care Information• Pharma Formulation/ R&D Services – Drug Discovery

• Pre Clinical R&D Services• Clinical Trials R&D Services• Bio and Analytical R& D Services• Bio Equivalence R&D Services• New formulation information services• Drug discovery dealers• Drug discovery & drug development R&D consultant• Bio technology R&D services• Bio informatics Research• Drug designing research• Chemical informatics• Phyto chemistry R&D services• New molecule research• Bio R&D services

• Who can do?: • Life Sciences, Biotech., Chemical Engg.,

B.Pharm, M.Pharm, BHMS, M.B.B.S., B.V. Sc., M.V.Sc., B.Tech, M. Tech, B.Sc, M.Sc, PhD, M.C.A, M.B.A, B.B.A and all degree final year students.

• Timings are flexible, for more details contact: +91- 9952968059

• Training-calendar

Contact us

• Enquiry & Registered Office: • CRC Group,

Chromosoft , Purasawalkam Division:No: 61, Jermiah Road, (Near Towton Hot Chips), Vepery, Chennai - 600 007.TeleFax : +91- 44 – 45126460Email : [email protected], [email protected] : www.crcgroupin.com