Osteogenesis imperfecta.

A. Opalescent dentin in a patient with osteogenesis imperfecta.

B. Bite-wing radiograph of the same patient showing shell teeth with thin dentin

and enamel of normal thickness.

Blue sclera in a patient with osteogenesis imperfecta

Osteopetrosis. This 24 -year-old white man has the infantile form of osteopetrosis. He has suffered from mandibular osteomyelitis And multiple draining fistulae are present on his face.

Osteopetrosis. Low-power photomicrograph showing sclerotic bone that is replacing the

normal cancellous bone. The inset shows a nodular pattern of the dense bone obliterating

the marrow spaces.

Cleidocranial dysplasia. The patient can almost approximate her shoulders in front of her chest.

Cleidocranial dysplasia. Panoramic radiograph showing

multiple unerupted teeth

Focal osteoporotic marrow defect. The periapicalfilm shows a radiolucent area containing fine trabeculatlons.

Focal osteoporotic marrow defect. Photornicrograph showing normal hematopoietic bone marrow.

Idiopathic osteosclerosis. A. An asymptomatic area of bane sclerosis is seen

between and apical to the roots of the first and second mandibular molars. B, no

appreciable change can be seen on this radiograph taken 10 years later.

Condensing osteitis. Increased areas of radiodensitysurrounding the apices of the nonvital mandibular firstmolar.

Bone scar. Residual area of increased radiodensityin the area of extraction of the mandibular first molar.

Paget's disease. Lateral skull film shows marked enlargement of the cranium with new bone formation above the outer table of the skull and a patchy, dense, "cotton wool“ appearance.

Paget's disease. Periapical film showing the"cotton wool" appearance of the bone.

Paget's disease. Prominent osteoblastic and osteoclastic activity surround the bone trabeculae. Note the resting and reversal lines.

Giant cell tumor. This photomicrograph shows large giant cells that are distributed in a cellular mesenchymal tissue. This specimen was froman aggressive lesion that had destroyed most of the maxilla.

Massive osteolysis. Periapical radiograph showing an ill-defined radiolucency associated with vital mandibular teeth.Note the loss of lamina dura.

Massive osteolysis. Panoramic radiograph of the same patient, showing extensive bone loss and a pathologic fracture of the left mandible. This destruction occurred over an 8-month period.

Massive osteolysis. Biopsy specimen from the same patient. The loose. Highly vascular connective tissue shows a diffuse chronic inflammatory cell infiltrate.