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Krok 1 Pharmacy 2009 1 1. Microscopical examination of pri- mary cortex of a root in its absorption zone revealed that it consisted mainly of multilayer living loose parenchyma with amyloid granules. It is called: A. Mesoderm B. Endoderm C. Exoderm D. Collenchyme E. Phellogene 2. A patient has been administered a competitive inhibitor of cholinesterase. Name it: A. Proserin B. Aspirin C. Sodium diclophenac D. Indometacin E. Allopurinol 3. A 30 year-old patient suffering from pulmonary tuberculosis, has been prescri- bed isoniazid. Continuous taking of this drug may lead to the deciency of the following vitamin: A. Pyridoxine B. Tocopherol C. Cobalamin D. Ergocalciferol E. Retinol 4. Active form of one of the sulphur- containing amino acids can be used as a methyl group donor for the drug methylation. Specify this amino acid: A. Methionine B. Glycin C. Glutamine D. Tyrosine E. Glutamate 5. A chemist in analytical laboratory needs to standardize solution of sodium hydroxide. What primary standard soluti- on can be applied for this purpose? A. Oxalic acid B. Acetate acid C. Chloride acid D. Sodium tatraborate E. Sodium chloride 6. A patient has taken a large dose of a barbiturate hypnotic (amytal) that inhibi- ts NAD-dependent dehydrogenase of the respiratory chain. What process running in the mitochondria will be disturbed? A. ATP synthesis B. Glycogen synthesis C. Amino acid synthesis D. Lipide synthesis E. Glucose synthesis 7. Particles of dispersed phase of an emulsion are deformed and look as polyhedrons. What emulsion is it? A. High-concentrated B. Concentrated C. Diluted D. Oil-in water E. Water-in-oil 8. A drug which inhibits ATP synthesis in a cell has been used during an experiment. What type of transmembrane transport will be disturbed? A. Active B. Diffusion C. Osmosis D. Filtration E. Facilitated diffusion 9. Increase in secretion of hydrochloric acid in the stomach of an experimental animal can be provoked by subcutaneous injection of the following gastrointestinal hormone: A. Gastrin B. Secretin C. Cholecystokinin D. Somatostatin E. Motilin 10. Protein digestion in the stomach is carried out by pepsin secreted in form of an inactive pepsinogen. Pepsinogen is converted to pepsin by the removal of the N-terminal peptide that is provoked by: A. Perchloric acid B. Sulfuric acid C. Acetic acid D. Bile acids E. Amino acids 11. In order to keep eubiotics viable and stable, frozen microorganisms are dried out under the conditions of high vacuum. This method is called: A. Lyophilization B. Pasteurization C. Tyndallization D. Inactivation E. Hybridization 12. Cardiac diseases are treated wi- th cocarboxylase preparation. This

Krok 1 - 2009 Question Paper (Pharmacy)

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1. Microscopical examination of pri-mary cortex of a root in its absorptionzone revealed that it consisted mainly ofmultilayer living loose parenchyma withamyloid granules. It is called:

A. MesodermB. EndodermC. ExodermD. CollenchymeE. Phellogene

2. A patient has been administered acompetitive inhibitor of cholinesterase.Name it:

A. ProserinB. AspirinC. Sodium diclophenacD. IndometacinE. Allopurinol

3. A 30 year-old patient suffering frompulmonary tuberculosis, has been prescri-bed isoniazid. Continuous taking of thisdrug may lead to the deficiency of thefollowing vitamin:

A. PyridoxineB. TocopherolC. CobalaminD. ErgocalciferolE. Retinol

4. Active form of one of the sulphur-containing amino acids can be usedas a methyl group donor for the drugmethylation. Specify this amino acid:

A. MethionineB. GlycinC. GlutamineD. TyrosineE. Glutamate

5. A chemist in analytical laboratoryneeds to standardize solution of sodiumhydroxide. What primary standard soluti-on can be applied for this purpose?

A. Oxalic acidB. Acetate acidC. Chloride acidD. Sodium tatraborateE. Sodium chloride

6. A patient has taken a large dose of abarbiturate hypnotic (amytal) that inhibi-ts NAD-dependent dehydrogenase of therespiratory chain. What process runningin the mitochondria will be disturbed?

A. ATP synthesisB. Glycogen synthesisC. Amino acid synthesisD. Lipide synthesisE. Glucose synthesis

7. Particles of dispersed phase of anemulsion are deformed and look aspolyhedrons. What emulsion is it?

A. High-concentratedB. ConcentratedC. DilutedD. Oil-in waterE. Water-in-oil

8. A drug which inhibits ATP synthesis ina cell has been used during an experiment.What type of transmembrane transportwill be disturbed?

A. ActiveB. DiffusionC. OsmosisD. FiltrationE. Facilitated diffusion

9. Increase in secretion of hydrochloricacid in the stomach of an experimentalanimal can be provoked by subcutaneousinjection of the following gastrointestinalhormone:

A. GastrinB. SecretinC. CholecystokininD. SomatostatinE. Motilin

10. Protein digestion in the stomach iscarried out by pepsin secreted in formof an inactive pepsinogen. Pepsinogen isconverted to pepsin by the removal of theN-terminal peptide that is provoked by:

A. Perchloric acidB. Sulfuric acidC. Acetic acidD. Bile acidsE. Amino acids

11. In order to keep eubiotics viable andstable, frozen microorganisms are driedout under the conditions of high vacuum.This method is called:

A. LyophilizationB. PasteurizationC. TyndallizationD. InactivationE. Hybridization

12. Cardiac diseases are treated wi-th cocarboxylase preparation. This

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preparation is the coenzymatic form ofthe following vitamin:

A. B1

B. B6

C. B12

D. CE. P

13. During starvation the normal rate ofglucose in blood is sustained due to thegluconeogenesis stimulation. Which ofthe following substances can be used asa source for glucose synthesis?

A. AlanineB. AdenineC. AmmoniaD. NicotinamideE. Urea

14. It is known that infectious type Bhepatitis is a systemic disease caused bythe type B hepatitis virus and characteri-zed by a predominant liver affection.Choose from the below given list thedrugs for the etiotropic therapy of thisinfection:

A. AcyclovirB. PenicillinC. TetracyclineD. SulfanilamidesE. Fluoroquinolones

15. Choose a non-salt-forming oxide fromthe following compounds:

A. N2OB. CuOC. P2O5

D. SO3

E. Na2O

16. What substance can act as both oxi-dant and reducer in oxidation-reductionreactions?

A. SO2

B. SO3

C. CO2

D. PbO2

E. CrO3

17. Oxidative deamination of biogenicamines in the tissues is catalyzed by thefollowing enzyme:

A. MonoaminooxidaseB. Aspartate transaminaseC. Alanine transaminaseD. DecarboxylaseE. Acetylcholinesterase

18. Nitrogen (I) oxide (N2O) is applied forinhalation narcosis. It is obtained by heati-ng of:

A. NH4NO3

B. NH3

C. Cu(NO3)2

D. NH4OHE. NaNO3

19. Quantitative determination ofpharmaceutical substances can be doneby means of acidimetry. Its titrant isthe secondary standard solution ofhydrochloric acid. According to whichcompound the precise concentration ofhydrochloric acid can be determined?

A. Sodium tetraborateB. Oxalic acidC. Potassium dichromateD. Sodium thiosulfateE. Magnesium sulphate

20. Analysis of a patient’s urine revealedincreased concentration of the uric acid.The patient was prescribed allopurinol.What is the biochemical mechanism of itsaction?

A. Xanthine oxidase inhibitionB. Cyclooxigenase activationC. Desaminase inhibitionD. Phosphorylase inhibitionE. Nucleosidase inhibition

21. Physical exercise results in an increasein thermogenesis due to an increase inheat production in the following structure:

A. Skeletal musclesB. HeartC. LungsD. LiverE. Brain

22. Plant pathogenic microorganismsrelate to various groups. Which of themcauses diseases of medicinal plants mostoften?

A. FungiB. VirusesC. BacteriaD. ActinomycetesE. Micoplasma

23. It is known that proteins, fats andcarbohydrates are digested by means ofproteases, lipases and amylases, respecti-vely. Which of digestive juices contains allthese groups of enzymes enough for di-gestion?

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A. Pancreatic juiceB. SalivaC. Gastric juiceD. BileE. Juice of large intestine

24. Colloidal protection is used whi-le manufacturing drug preparations.Name the preparation of colloidal silverprotected by proteins:

A. ProtargolB. FestalC. EnzymtalD. ArgentumE. Collagen

25. It is known that the unconjugatedbilirubin being the product of hemecatabolism is detoxicated in liver. Whichcompound is involved into the bilirubindetoxication within the hepatocytes?

A. Glucuronic acidB. UreaC. Mevalonic acidD. Lactic acidE. Glycin

26. An adult presents with systemic arteri-al pressure at the rate of 160/100 mm Hg.This might be caused by the increasedconcentration of the following hormonein blood:

A. AdrenalinB. AldosteroneC. GlucagonD. CortisolE. Thyroxin

27. It is required to diminish pump functi-on of patient’s heart. This can be doneby means of blockers of the followingmembrane cytoreceptors:

A. β-adrenoreceptorsB. Nicotinic cholinoreceptorsC. Muscarinic cholinoreceptorsD. α-adrenoreceptorsE. Dopamine receptors

28. Taking vasopressin resulted in adecrease in diuresis. The reason for itis increased water reabsorption in thefollowing renal tubuli:

A. Distal convoluted tubuli and receivingtubesB. Proximal convoluted tubuliC. Henle’s loopsD. Descending limbs of Henle’s loopsE. Ascending limbs of Henle’s loops

29. Under conditions of high exteriortemperature a ventilating fan can relievestaying in the premises because it intesifi-es heat emission by means of:

A. ConvectionB. Liquid evaporationC. Heat radiationD. Heat conductionE. Heat radiation and conduction

30. In the pharmaceutical productionprocesses of drug synthesis take placeunder different conditions. Entropy staysunchanged in the following process:

A. AdiabaticB. IsothermalC. IsochoricD. IsobaricE. Polytropic

31. Specify the complexing agent for acomplex compound K2[HgI4]:

A. Hg2+

B. K+

C. I−

D. HgI2−4

E. K2[HgI4]

32. Analysis of a patient’s urine showed anincrease in Na+ ions concentration and adecrease is K+ ions concentration. Thismight be caused by the reduced secretionof the following hormone:

A. AldosteroneB. InsulinC. ThyroxineD. HydrocortisoneE. Prolactin

33. Choose a reagent for synthesis ofacetic acid hydrazide from ethyl acetate:

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A. H2N − NH2

B. N�3

C. H2N − CH3

D. C6H5NH2

E. C6H5NHNH2

34. When computing quantities ofadjuvant substances required to make li-quid drug forms isotonic, the values ofisotonic quotients are used. What is thequotient for zinc sulphate if known thatit dissociates completely in an aqueoussolution?

A. 2B. 0C. 1D. 3E. 4

35. After a stomach resection a pati-ent presented with weakness, skin pallor,face puffiness, enlargement of liver andspleen. Analysis of the peripheral bloodrevealed megaloblasts and megalocytes;hyperchromatism (colour index - 1,3).What type of anaemia is observed in thispatient?

A. B12-deficientB. HaemolyticC. HypoplasticD. Iron-deficientE. Toxic

36. Water-soluble vitamins take coenzymeform in an organism. Thiamine di-phosphate is coenzyme of the followingvitamin:

A. B1

B. B2

C. CD. B6

E. B12

37. Quantitative determination of calciumchloride is carried out by method of directchelatometric titration. Choose an indi-cator for fixation of the titration endpoint:

A. Eriochrome black TB. PhenolphthaleinC. Methyl redD. EosinE. Starch

38. One of the examined soft fruits ischaracterized by essential-oil exocarp,spongioid mesocarp and overgrownendocarp that consists of juice saccules.What fruit was under examination?

A. HesperidiumB. PepoC. MulticoccusD. DrupeE. Bacca

39. Enzymes (biological catalysts) areused as pharmacologic preparations.What is the mechanism of enzyme acti-on in the biochemical reactions?

A. They reduce the energy of reactionactivationB. They increase the energy of reactionactivationC. They inhibit the reaction processD. They change the constant of the reacti-on rateE. They change the reaction order

40. After a solution had been heated wi-th (NH4)2S2O8 in presence of AgNO3, itturned crimson. What ions were presentin the solution?

A. Mn2+

B. Fe3+

C. Fe2+

D. Co2+

E. Cu2+

41. A solution under examinationwas added to the solution of FeSO4

in presence of concentrated H2SO4.Generation of a brown ring indicatespresence of:

A. Nitrate ionsB. Acetate ionsC. Carbonate ionsD. Oxalate ionsE. Phosphate ions

42. Specify standard substances usedfor standardization of titrant soluti-ons (NaOH , KOH) in the alkalimetricmethod:

A. Oxalic and succinic acidsB. Acetic and succinic acidsC. Formic and acetic acidsD. Sulphanilic and oxalic acidsE. Sulphanilic and salicylic acids

43. Irritation of the sympathetic nervein an experimental dog induces quanti-tative and qualitative alterations in thesaliva composition. What alterations areinduced?

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A. Little saliva, a lot of enzymesB. A lot of saliva, a lot of enzymesC. Little saliva, few enzymesD. A lot of saliva, few enzymesE. A lot of saliva, no enzymes

44. Kinetic methods are used for determi-nation of drug stability. What is the orderof reaction if its rate constant equals toc−1?

A. FirstB. ZeroC. FractionalD. SecondE. Third

45. Underneath the stem epidermis somelayers of living perenchymal cells werefound. The cells contained chloroplastsand had cellulose membranes with thi-ckened angles. This tissue is called:

A. Angular collenchymeB. Lacunar collenchymeC. Lamellar collenchymeD. Storage parenchymeE. Chlorophyll-containing parenchyme

46. Which of the following oxides is theanhydride of nitric acid?

A. N2O3

B. N2O5

C. N2O4

D. NOE. NO2

47. What is the product of ethyl alcohol-acetic aldehyde reaction?

A.

B.

C.

D.

E.

48. Choose the carbocation among the gi-ven intermediate reactive particles:

A.

B.

C.

D.

E.

49. 1 M sulphuric acid solution was addedto the solution under study. This resultedin formation of white sediment that wassoluble in the alkalies. This indicated thatthe solution contains:

A. Plumbum cationsB. Calcium cationsC. Barium cationsD. Argentum cationsE. Mercury (I) cations

50. Argentum nitrate solution was addedto a solution containing anions of thesecond analytical group. This resulted information of light-yellow sediment thatwas insoluble in the nitric acid and partly

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soluble in the ammonia solution. Whatanions were present in the solution?

A. Bromide ionsB. Iodide ionsC. Chloride ionsD. Sulphide ionsE. Arsenite ions

51. A patient has bradycardia, moderatehypotension, decrease of basal metaboli-sm, edemata. What abnormality caninduce such syndrome?

A. Thyroid hypofunctionB. Parathyroid hypofunctionC. Thyroid hyperfunctionD. Parathyroid hyperfunctionE. Adrenal hypofunction

52. Most cases of alimentary starvati-on are accompanied by developmentof evident edemata. What is the leadi-ng pathogenetic mechanism of edematadevelopment in this case?

A. Fall of oncotic pressure of blood plasmaB. Rise of hydrostatic pressure in thecapillariesC. Fall of hydrostatic pressure in the tissuesD. Rise of oncotic pressure in theintercellular fluidE. Fall of osmotic pressure in theintercellular fluid

53. A patient suffering from pleuritisunderwent pleural puncture. There wasobtained a transparent odourless liquid.What type of exudate was obtained?

A. SerousB. HaemorrhagicC. PurulentD. FibrinousE. Putrefactive

54. Examination of a medicinal plantrevealed that its underground organ hadnodes, internodes, cataphylls, gemmaeand secondary roots. Therefore, thisunderground organ is:

A. RhizomeB. Storage rootC. Root bulbD. StolonE. Tuber

55. A patient took a maximal deep breath.Air volume being present in lungs underthese conditions is called:

A. Total lung capacityB. Vital lung capacityC. Tidal volumeD. Residual volumeE. Inspiratory reserve volume

56. Choose a reagent that can be used forproduction of propanol−2 out of acetone:

A. H2 (Ni)B. CH3OHC. CH3ID. HCNE. HCOH

57. Galactose belongs to the aldehydealcohols and similarly to aldehydesinteracts with hydrocyanic acid (HCN)according to the following mechanism:

A. AN

B. SN1C. SN2D. AE

E. SR

58. Identify the succinimide (succinic acidimide) among the given compounds:

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A.

B.

C. H2NOC − CH2 − CH2 − CONH2

D. H2NOC−CH2−CH2−CH2−CONH2

E.

59. Ammonia is generated in different ti-ssues and organs and then transported toliver for detoxication and conversion intourea. What amino acid transports it fromskeletal muscles to liver?

A. AlanineB. HistidineC. GlycinD. SerineE. Valine

60. For production of phenol ether it isnecessary to cause reaction of sodiumphenoxide with:

A. CH3ClB. CH3OHC. CH4

D. CH3NH2

E. CH3C ≡ N

61. A higher nonvascular plant has di-stinct alternation of dominant sexual(gametophyte) and reduced asexual(sporophyte) generations. This indicatesthat the plant belongs to the following di-

vision:

A. BryophytaB. LycopsidaC. EquisetophytaD. PteridophytaE. Gymnospermae

62. A fruit under examination ispseudomonocarpic, with woody pericarpand one seed. The seed cuticle remainsunfused with the pericarp. Such fruit iscalled:

A. NutB. CremocarpC. AchenocarpD. CaryopsisE. Pseudomonocarpic drupe

63. The birch has compound inflorescenceswith drooping main axis bearing dichasiacomposed of unisexual cells. Therefore,this inflorescence is called:

A. AmentB. RacemeC. SpadixD. SpikeE. Glomus

64. A female patient bitten by a stray dogcame to a surgery. Wide lacerated woundswere localized on the patient’s face. Whattreatment-and prevention aid should berendered in order to prevent rabies?

A. Immunization with the antirabic vacci-neB. Combined antibiotic therapyC. Hospitalization, injection of diphtheria-pertussis-tetanus vaccineD. Hospitalization, medical surveillanceE. Urgent injection of normal gamma-globulin

65. It is suspected that the workersof a serum drugs plant at a regionalhemotransfusion station are carriers ofpathogenic staphylococcus aureus. Inorder to detect staphylococcus carriage,the material from the nasopharynx of theworkers should be inoculated into thefollowing medium:

A. Egg-yolk-salt agarB. Endo agarC. Meat infusion brothD. Kessler mediumE. Blood agar

66. Analysis of sputum obtained froma patient with suspected pneumonia

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revealed gram-positive diplococci. Theywere slightly elongated, with the pointedopposite ends. What microorganisms wererevealed in the sputum?

A. Streptococcus pneumoniaeB. Staphylococcus aureusC. Klebsiella pneumoniaeD. Neisseria meningitidisE. Streptococcus pyogenes

67. Examination of air state in drugstorepremises for preparation of injectiondrugs was done by method of sedimentati-on. It revealed 5 small roundish coloni-es with zone of hemolysis around them.Inoculations were made on the followingcultural medium:

A. Blood agarB. Endo agarC. Meat infusion agarD. Egg yolk and salt agarE. Lewin’s agar

68. According to the Pharmacopoeiarequirements, all drugs for topical admi-nistration should be tested for “microbi-ological purity”. Inapplicability of thisdrug group in the medical practice is indi-cated by presence of the following mi-croorganisms:

A. Staphylococcus aureusB. Yeast fungiC. Saprophytic staphylococciD. Mold fungiE. Sarcinae

69. A pharmacy produced a batch of vialswith glucose diluent for injections. Whatis the best way for their sterilization?

A. Autoclave sterilization by flowing steam(fractional method)B. Autoclave sterilization under 2atmosphere pressureC. Dry-heat sterilizationD. X-ray exposureE. UV exposure

70. When producing some liquid drugforms, it is necessary to take into accounttheir osmotic pressure. The highestosmotic pressure is characteristic for the0,1 M solution of the following substance:

A. AlCl3B. GlucoseC. SaccharoseD. CaCl2E. KNO3

71. Which of the following indices ofthe external respiration characterizes themaximum volume of air that a person canexhale after maximum inhalation?

A. Lung vital capacityB. Total lung capacityC. Functional residual capacityD. Expiratory reserve volumeE. Respiratory volume

72. The air in a room has increasedconcentration of carbonic acid. Whatrespiratory changes (depth and rate) willbe observed in a person after entering thisroom?

A. Increase in respiration rate and depthB. Decrease in respiration rate and depthC. Decrease in respiration depth andincrease in respiration rateD. Increase in respiration depth anddecrease in respiration rateE. There will be no respiratory changes

73. Vitamin A is quickly oxidized in theopen air and hereupon looses its bi-ological activity. What component of thefoodstuffs mainly prevents the oxidationof the vitamin?

A. TocopherolB. Nicotinic acidC. Common saltD. ProteinE. Fat

74. Specify the standardized solutionsused for direct and back titration ofreducing agents in the iodometric method:

A. I2, Na2S2O3

B. K2Cr2O7, Na2S2O3

C. I2, KID. KMnO4, KIE. K2Cr2O7, I2

75. By heating aniline with concentratedsulphuric acid the following compoundcan be obtained:

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A.

B.

C.

D.

E.

76. During the quantitative analysis carri-ed out under the primary conditions,a specific reagent to Fe3+ cations isK4[Fe(CN)6]. Their interaction gives aprecipitate of the following colour:

A. BlueB. WhiteC. BrownD. RedE. Black

77. From a patient with the symptomsof acute meningitis the spinal fluid wastaken. Its smears contained gram-negativediplococci within the leukocytes andoutside them. Which microorganism is themost likely cause of the disease?

A. Neisseria meningitidisB. Haemophilus influenzaeC. Streptococcus pneumoniaeD. Candida albicansE. Escherichia coli

78. Potentiometric method of pHdetermination is regarded as the mostuniversal and enters into the Nati-onal Pharmacopeia of Ukraine. Whichelectrode is used as a reference electrode?

A. Saturated calomelB. QuinhydroneC. GlassD. HydrogenE. Zinc

79. Sodium nitrite is used in medicine asa vasodilating drug against stenocardia.NaNO2 acts as reducer with the followingcompound:

A. KMnO4

B. H2SC. NH3

D. KIE. NaHCO3

80. Most technological processed inpharmaceutics run in heterogenoussystems. How many phases has an eutecticcomposition under eutectic temperatureof two-component system?

A. 3B. 2C. 5D. 4E. 1

81. Sulphur (IV) oxide is a constituentpart of one of the most harmful envi-ronment pollutants called toxic smog.When dissolved in water, sulphur (IV) oxi-de forms the following acid:

A. SulphurousB. SulphuricC. HydrosulphuricD. ThiosulfateE. Tetrathionate

82. Micelle solutions of surfactants areapplied in pharmaceutical production asstabilizers and solubilizers. What soluti-on of colloidal surfactants will have thegreatest value of critical concentration ofmicelle formation?

A. C9H19SO3NaB. C14H29SO3NaC. C16H33SO3NaD. C12H25SO3NaE. C10H21SO3Na

83. In the pharmaceutical industry, themicelle-forming solutions of surface-active substances are used for producti-on of water-soluble preparations out ofwater-insoluble substances, for examplevitamins A and E. The critical concentrati-on of micelle formation has the lowestvalue in the solutions of the followingsubstances:

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A. C17H35COONaB. C12H25COONaC. C13H27COONaD. C15H31COONaE. C11H23COONa

84. Specify the titration method, in whicha standardized titrant solution is graduallyadded to the solution under study until atitration endpoint is reached:

A. Direct titrationB. Back titrationC. Indirect titrationD. Substitution titrationE. Residue titration

85. The given reaction is called:

�6�12�6enzymes−−−−−→ 2�2�5��+ 2��2?

A. Alcohol fermentation of glucoseB. Glucose hydrolysisC. Glucose oxidationD. Lactic-acid fermentation of glucoseE. Glucose reduction

86. Which of the following formulascorresponds to the electronic configurati-on of Cu atom?

A. [Ar] 3d10 4s1

B. [Ar] 3d9 4s2

C. [Ar] 3d6 4s2

D. [Ar] 3d8 4s2

E. [Ar] 3d7 4s2

87. Early pregnancy test involves analysisof a woman’s urine. Pregnancy isascertained by presence of the followinghormone:

A. Chorionic gonadotropinB. EstriolC. AldosteroneD. TestosteroneE. Progesterone

88. Microbiological assay of a pepperminttincture established its discrepancy withthe Pharmacopoeia requirements. It wasfound to contain pathogenic microflora.The reason for such a conclusion was thepresence of the following microflora:

A. Blue pus bacillusB. Yeast fungiC. Epidermal staphylococcusD. Mold fungiE. Micrococci

89. Which electronic configuration ofvalence electrons is corresponding to anelement of the 4th period, VI group, mainsubgroup?

A. 4s2 4p4

B. 4s1 3d5

C. 6s2 6p2

D. 6s2 5d2

E. 3s2 3p4

90. According to the mass action law,velocity of process 2SO2 (g) + O2 (g) =2SO3 (g) is expressed as:

A. k [SO2]2 x [O2]

B. [2SO2] x [O2]C. k [SO2] x [O2]D. k [SO2] + [O2]E. [SO2]

2 + [O2]

91. What saturated heated solution is usedfor transformation of sulphates BaSO4,SrSO4, CaSO4 to carbonates during thesystematic analysis?

A. Na2CO3

B. CaCO3

C. (NH4)2CO3

D. MgCO3

E. CO2

92. Which indicatorless method enablesquantitative determination of iron (II)content?

A. PermanganatometryB. ChelatometryC. ArgentometryD. IodometryE. Nitritometry

93. Thresholds of coagulation of a drug solby electrolytes MgSO4, NaCl, Al(NO3)3

are equal to 0,81; 51,0; 0,095 millimole/lcorrespondingly. Which electrolyte ionhas the maximal coagulating effect?

A. Al3+

B. Mg2+

C. Na+

D. Cl−

E. SO2−4

94. Iodoform when stored decomposesspontaneously into free iodine. Whichthermochemical function is a criterion forthis process direction when V and T areconstant?

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A. Helmholtz energy FB. Entropy SC. Enthalpy HD. Gibbs energy GE. Intrinsic energy U

95. Glycosidic (hemiacetal) hydroxyl ina molecule of α-D-glucose pyranose isbonded to the following carbon atom:

A. C1

B. C2

C. C3

D. C4

E. C6

96. Microscopic examination of a potatotuber showed some cell inclusions thatbecome blue-violet as affected by Lugol’siodine solution. These inclusions are:

A. Starch granulesB. Aleurone grainsC. Drops of fatty oilD. Insulin crystalsE. Calcium oxalate crystals

97. Chlorophyll, the green pigment ofplants, is a chelate compound. Specify thechelating ion in the chlorophyll:

A. Mg2+

B. Fe3+

C. Mn2+

D. Fe2+

E. Ni2+

98. Prevailing plants of a foliage forest aremonoecious high trees coated with thi-ck dark-grey rind with deep cracks. Theirleaves are short-petiolar, pinnatilobate.Their fruit is acorn. Therefore, the domi-nating species is:

A. Quercus roburB. Robinia pseudoacaciaC. Aesculus hippocastanumD. Tilia cordataE. Betula verrucosa

99. Potassium dichromate K2Cr2O7 isapplied as oxidant in acidic medium. Whatis the product of reduction of dichromate-

ion Cr2O2−7 under these conditions?

A. Cr3+

B. Cr(OH)3

C. Cr(OH)2

D. [Cr(OH)6]3−

E. Cr2O3

100. Medicinal plants collected at aplantation included a lot of plants withmosaic-coloured leaves. What is the mostlikely causative agent of such infection?

A. Phytopathogenic virusesB. Phytopathogenic bacteriaC. Toxic substances of the soilD. Microscopic mitesE. Nematode worms

101. A pharmaceutic factory recei-ved a batch of crude herbal drugs forphytomedicines production. To evaluatequality of these crude drugs it is necessaryto determine:

A. Total number of microorganisms pro 1g of thecrude drugB. Coli titerC. Coli indexD. AntimicrobialE. Pyrogens

102. The leukocytes that are the first toappear in a focus of inflammation arecalled:

A. NeutrophilsB. MonocytesC. EosinophilsD. LymphocytesE. Basophils

103. The most active component in theaniline acylation reaction is:

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A.

B.

C.

D.

E.

104. Staphylococci were isolated inpure culture from a patient with sepsis.These were staphylococci producingbetalactamase. Such property should betaken into account when:

A. Choosing an antibiotic for treatmentB. Determining biiochemical propertiesC. Determining the strain pathogenicityD. Differentiating specific types ofstaphylococciE. Choosing optimal conditions for culti-vation

105. It is required to determine amount ofsodium salicylate in a solution. What ti-trimetric method can be applied for thequantitative determination of aromaticcompounds?

A. BromometryB. MercurimetryC. CerimetryD. ArgentometryE. Chelatometry

106. In order to determine mass fractionof calcium in a pharmaceutical preparati-on, gravimetric method was applied.Ammonium oxalate solution was used asa precipitating agent. What is the gravi-metric form in this case?

A. Calcium chlorideB. Anhydrous calcium oxalateC. Monohydrous calcium oxalateD. Calcium carbonateE. Calcium hydroxide

107. A man’s tip of tongue was processedwith an anesthetic solution. Therefore hewill loose the sense of the following taste:

A. SweetB. BitterC. SourD. SaltyE. Bitter and salty

108. Anti-inflammatory effect of anumber of drugs is caused by the inhibiti-on of arachidonic acid release. This acid isthe precursor of:

A. ProstaglandinsB. Uric acidC. UreaD. HaemE. Cholesterol

109. Dark-violet colour appears, whenFeCl3 solution is added to the followi-ng substance:

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A.

B.

C.

D.

E.

110. Inoculation of hen’s embryos is themain method of detection of influenzavirus. In order to neutralize associatedbacterial flora in the material underexamination (nasopharyngeal lavage) itis necessary to add beforehand:

A. AntibioticsB. EubioticsC. Fluorescent serumD. Leukocytic interferonE. Ant-influenza gamma globulin

111. Interaction of lactic acid with SOCl2excess will result in generation of thefollowing compound:

A.

B.

C.

D.

E.

112. A female patient consulted a doctorabout leg pain that arises usually towardthe evening; feet and shins edemata.Objectively: leg skin is cyanotic, cold tothe touch. What type of peripheral ci-rculation disorder does the patient presentwith?

A. Venous hyperaemiaB. Arterial hyperaemiaC. IschaemiaD. StasisE. Thrombosis

113. A patient 42 year old sufferi-ng from chronic calculous cholecysti-tis complains about acute pain inthe right subcostal area, itching andskin icteritiousness, multiple petechi-al haemorrhages, saponified and light-coloured feces (steatorrhea). What typeof icterus is it?

A. MechanicB. HemolyticC. ParenchymatousD. CythemolyticE. Hepatocellular

114. Specify the relevant indicators for fi-xation of the titration endpoint when usi-

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ng nitritometric method:

A. Tropeolin 00 + methylene blueB. Methylene blueC. Methylene orangeD. Starch solutionE. Diphenylamine

115. Presence of the pathogenic mi-croorganisms in the air can be prognosti-cated according to the content of sanitary-indicative bacteria. Which bacteria indi-cate immediate epidemiologic danger?

A. Haemolytic streptococciB. SarcinaeC. Mold fungiD. Yeast fungiE. Micrococci

116. To prevent fatty degeneration of liverafter viral hepatitis, a patient should beadministered lipotropic factors. Indicateone of them:

A. CholineB. TryptophaneC. AllopurinolD. ContricalE. Vicasol

117. Hybridization of one s− and 2�−orbitals leads to formation of three s�2-hybrid orbitals. Specify the angle betweenthese orbitals:

A. 120o

B. 180o

C. 109o

D. 90o

E. 104, 5o

118. Toluol is converted to the benzoicacid under the following conditions:

A. Oxidation with potassiumpermanganateB. Heating with sulphuric acidC. Hydrogen peroxide action at a roomtemperatureD. Sodium hydroxide action at a roomtemperatureE. Boiling in the open air

119. Which of the following compounds

forms a propionic aldehyde as a result ofalkaline hydrolysis (H2O, OH−)?

A.

B.

C.

D.

E.

120. During thin-layer chromatographyof novocaine, the developed platerepresented a stain 3 cm away from thestart line, and the length of solvent frontwas 10 cm. What is the Rf value ofnovocaine?

A. 0,3B. 0,4C. 0,5D. 0,6E. 0,7

121. For quantitative determination ofsome drugs the solutions of sulfuric andperchloric acids are applied. Which ofthe following oxides are the anhydridesof these acids?

A. SO3, Cl2O7

B. SO2, Cl2OC. SO3, ClO2

D. SO2, Cl2O7

E. SO2, Cl2O7

122. A patient suffers from the cerebralatherosclerosis. Blood count showedhyperlipoproteinemia. You will most li-kely observe increase in the concentrationof the following plasma lipoprotein class:

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A. Low-density lipoproteinsB. High-density lipoproteinsC. ChylomicronsD. Globulin complexes with steroidhormonesE. Fatty acid complexes with albumines

123. Inflammatory processes in the gallbladder exert negative influence on thecolloidal properties of bile. This may leadto gallstone formation. One of the causesof their formation is the crystallization ofthe following substance:

A. CholesterolB. AlbumineC. HaemoglobinD. UratesE. Oxalates

124. A 55-year-old woman with renal fai-lure has arterial pressure at the rate of170/100 mm Hg. Stable pressure rise iscaused by hyperactivity of the followingsystem:

A. Renin-angiotensin-aldosteroneB. SympathoadrenalC. Hypothalamo-pituitaryD. Central nervousE. Kallikrein-kinin

125. What method of titrimetric analysiscan be applied for the quantitativedetermination of sulphuric acid by meansof the potassium hydroxide solution?

A. AlkalimetryB. AcidimetryC. Oxidation-reductionD. PrecipitationE. Complexation

126. General formula of alkynes is�nH2n−2. Isomerous alkynes fall into thefollowing compound class:

A. AlkadienesB. AlkenesC. CycloalkanesD. Mononuclear arenesE. Multinuclear arenes

127. Diphenylmethane can be derivedfrom benzol by means of the followingreagent:

A. CH2Cl2B. C2H5ClC. CH2OD. CH3COOHE. NaNH2

128. Pharmaceutical practice involves useof microheterogeneous systems with li-quid disperse medium and solid dispersephase. Such drug form is:

A. SuspensionB. FoamC. PowderD. AerosolE. Emulsion

129. What is the number of degrees offreedom for the salol-camphor system,provided that both components crystallizefrom the melt simultaneously?

A. 0B. 1C. 2D. 3E. - 1

130. Choose the reagents for detection ofthe sulphate ions in a solution containingcarbonate, sulphate and phosphate ions:

A. Ba(NO3)2, HClB. Ba(NO3)

−2, NaOHC. BaCl2, H2OD. CaCl2, NH4OHE. AgNO3, HNO3

131. A big brown alga has a stipe, rhizoidsand laminae rich in alginates and iodine.It belongs to the following genus:

A. LaminariaB. ChlorellaC. ChlamydomonasD. SpirogiraE. Ulothrix

132. Aetiological factors for the infecti-ous diseases are often microorganisms wi-th various ultrastructure. Which of thefollowing microorganism groups relatesto the eucariots?

A. ProtozoaB. VirusesC. ViroidsD. PrionsE. Scotobacteria

133. After a birth trauma a newbornpresents with limited movements ofthe right upper extremity, hyporeflexia,myatrophy. These changes relate to the

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following type of motor dysfunctions:

A. Peripheric (atonic) paralysisB. Central paralysisC. MyastheniaD. Bulbar paralysisE. Neuritis

134. Temperature quotient of the reactionvelocity is equal to 2. In how many timesdoes the reaction velocity change, if thetemperature changes by 40oC?

A. In 16 timesB. In 8 timesC. In 4 timesD. In 32 timesE. In 24 times

135. Surface-active substances are widelyused in the drug production. Specify asurface-active substance present at theaqueous solution-air interface:

A. Butyric acidB. SaccharoseC. NaClD. NaOHE. HCl

136. What type of tautomerism is typicalfor the given compound?

A. Nitro-aci-nitro tautomerismB. Carbonyl-enol tautomerismC. Cyclo-oxo tautomerismD. Amine-imine tautomerismE. Keto-enol tautomerism

137. Microscopic examination of a ficusleaf revealed in some cells of its epidermisa protrusion of the cell membrane with anaccumulation of crystals that dissolve inthe hydrochloric acid and release carbonicacid gas. This structure is called:

A. CystolithB. RaphideC. DruseD. Single crystalE. Styloid

138. Alpha-cells of pancreas stimulatesynthesis of the glucagon hormone that isinvolved into the carbohydrate metaboli-sm. It has the following effect on liverprocesses:

A. Activates glycogenolysisB. Activates alcoholic fermentationC. Inhibits glycogenolysisD. Inhibits glycolysisE. Activates lypogenesis

139. Sol Al(OH)3 was derived by processi-ng a freshly made Al(OH)3 precipitatewith a small amount of HCl solution.Sol production bases upon the followingphenomenon:

A. Chemical peptizationB. Chemical condensationC. Rinsing with a solventD. Mechanic dispersingE. Physical condensation

140. What is the molecular weight of anundefined gas knowing that its density is20 relative to the density of hydrogen?

A. 40 g/moleB. 10 g/moleC. 20 g/moleD. 30 g/moleE. 50 g/mole

141. How much sodium hydroxide isrequired to prepare 500 g of 10% sodi-um hydroxide solution?

A. 50 gB. 0,5 gC. 5 gD. 10 gE. 25 g

142. A 37-year-old man was admittedto a hospital with an attack of bronchi-al asthma. What respiration type will beobserved in this patient?

A. Expiratory dyspneaB. Inspiratory dyspneaC. ApnoeaD. Gasping respirationE. Hyperpnoea

143. After a bacteriological analysis atableted medication was considered to beinapplicable, though its general microbi-al contamination was within the norm.The reason for such a conclusion was thepresence of the following microorganisms:

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A. EnterobacteriaB. Mold fungiC. ActinomycetesD. MicrococciE. Sarcinae

144. An essential oil plant under exami-nation has a square stem, flowers withbilabiate corolla, coenobium fruit. Thesecharacteristics are typical for the followi-ng family:

A. LamiaceaeB. PapaveraceaeC. PolygonaceaeD. SolanaceaeE. Scrophulariaceae

145. Concentration of different ions withinthe cytoplasm of a neurocyte has beenmeasured during an experiment. The hi-ghest ion concentration was observed in:

A. K+

B. Na+

C. Cl−

D. Ca2+

E. HCO3−

146. Specify the molecular formula of theoxide whose conjugate is permanganicacid:

A. Mn2O7

B. Mn3O4

C. Mn2O3

D. MnO2

E. MnO

147. A patient presents with weakeningof the inhibitory processes of CNS whi-ch is associated with disturbed producti-on of gamma-aminobutyric acid. Whatsubstance is the GABA precursor?

A. GlutamateB. TryptophaneC. MethionineD. ValineE. Glycin

148. Drugs in form of colloidal-and-disperse systems are widely spread in thepharmaceutical practice. What methodof sol production is based upon thephenomenon of physical condensation?

A. Solvent substitutionB. ReductionC. OxidationD. HydrolysisE. Double exchange

149. The best swelling of gelatine will be

observed in the following solvent:

A. WaterB. BenzolC. Ethyl alcoholD. ChloroformE. Acetone

150. A patient suffering from the bonemarrow form of radiation sickness wasfound to have the following changesin his hemogram: leukocytes - 2 · 109/l,lymphopenia, erythrocytes - 3, 0 · 1012/l,Hb- 52 g/l, thrombocytes - 105 · 109/l,reduced blood coagulation. These changesare typical for the following stage of theradiation sickness:

A. FastigiumB. Latent periodC. Prodromal periodD. SolutionE. Relapse

151. Immediate-type allergies arecharacterized by degranulation of the ti-ssue basophils that secrete biologicallyactive substances. One of such substancesis:

A. HistamineB. AcetylcholineC. PlasminogenD. Hageman’s factorE. Thromboxane

152. A 56-year-old female patientcomplains about a fast growing hardneoplasm in the mammary gland thatappeared a month ago. Objectively: theformation is fused with the surroundi-ng tissues, it is uneven, slightly painful.What are the peculiarities favouring theinfiltrative growth of a malignant tumour?

A. Lack of contact inhibitionB. Intensified chalone formationC. Intensified contact inhibitionD. Intensified formation of tight contactsE. Rise of embryonal antigens

153. During the field practice a studentfound a plant with disk-shaped structureof its rachis, sessile flowers and husk. Thisinflorescence is called:

A. AnthodiumB. SpikeC. SpadixD. GlomusE. Raceme

154. As a result of staining of a plant mi-

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croslide with Sudan III solution the cellmembranes turned pink. This indicatesthe presence of:

A. SuberinB. CelluloseC. LigninD. PectinE. Hemicellulose

155. After a plant microslide had beenprocessed with phloroglucinol togetherwith concentrated hydrochloric acid, thecell membranes turned crimson red. Thisindicates presence of:

A. LigninB. PectinC. CelluloseD. HemicelluloseE. Suberin

156. Nitritometric determination ofcompounds containing primary aromaticamino group can be carried out under thefollowing conditions:

A. With observation of all the mentionedconditionsB. At a temperature up to 10oCC. With adding of the crystalline KBr(catalyst)D. Chloric acid excessE. Slow titration

157. What electrode is used as indicatorduring dichromatometric determinationof FeSO4 in a solution provided that fi-xation of the equivalence point is done bya potentiometric method?

A. PlatinumB. GlassC. QuinhydroneD. SilverE. Silver chloride

158. Inflorescence of Ledum palustre hasa significantly shortened rachis, conniventnodes, pedicles of the quite similar length.This inflorescence is called:

A. UmbelB. GlomusC. BostryxD. SpikeE. Ament

159. Reaction of pyruvic acid in whichthe ketone functional group takes placeproceeds with the following reagent:

A. HCNB. NaOHC. SOCl2D. FeCl3E. CH3OH (H+)

160. Which of the following compoundshas acidophobic properties?

A. PyrroleB. PyrazoleC. PyridineD. PyrimidineE. Imidazole

161. What reagent can demonstratepresence of an aldehyde group in afurfural molecule?

A. [Ag(NH3)2]OHB. (CH3CO)2OC. NaNO2

D. NH3

E. NaOH

162. A patient present’s with Kussmaul’srespiration, acetone smell from themouth; low tonus of eyeballs, myoticpupils, dry skin, polyuria, glycosuria,hyperglycemia. Such symptom complexis typical for the following coma:

A. DiabeticB. HepaticC. Alimentary dystrophicD. HypoglycemicE. Adrenal

163. Heart automatism is possible dueto the atypical cardiomyocytes formi-ng the cardiac conduction system. Whatpart of this system is the primary cardiacpacemaker?

A. Sinoatrial nodeB. Purkinje’s fibersC. Atrioventricular nodeD. His’ bundleE. His’ bundle branches

164. Essential oil glandules consisting of 8

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secretory cells arranged in two rows andfour tiers can be be found in most plantsof the following family:

A. AsteraceaeB. ApiaceaeC. LamiaceaeD. RosaceaeE. Scrophulariaceae

165. To relax skeletal muscles duringcomplex surgeries, curarelike substancesare applied. These substances block thefollowing structure:

A. Neuromuscular synapsesB. Basal ganglionsC. Red nuclei of the mesencephalonD. Synaptic structures of the spinal cordE. Vegetative ganglions

166. Anxious condition can be characteri-zed by reduced salivation and sense ofdry mouth. What mediator is exuded outof nerve terminals innervating salivaryglands?

A. NoradrenalineB. AcetylcholineC. SerotoninD. HistamineE. GABA

167. A patient complains about anincrease in heart rate, hyperperspirati-on, irritability, sleeplessness. He has beenpresenting with these symptoms for thelatest six months. They indicate thehyperfunction of the following endocri-ne gland:

A. Thyroid glandB. PancreasC. Adrenal glandsD. Sexual glandsE. Thymus

168. What mediator provides informati-on transmission from nerve terminationsof motoneurons to the fibers of skeletalmuscles?

A. AcetylcholineB. AdrenalineC. NoradrenalineD. SerotoninE. GABA

169. What is the mechanism of additionreaction of ethanol to acetaldehyde?

A. AN nucleophylic additionB. AE electrophylic additionC. SE electrophylic additionD. SN nucleophylic substitutionE. SR radical substitution

170. The highest bromination rate will beobserved for the following compound:

A.

B.

C.

D.

E.

171. Examination of five herbarium speci-mens of medicinal plants showed that oneof them belonged to the legume family,namely:

A. Glycyrhiza glabraB. Atropa belladonnaC. Hyoscyamus nigerD. Datura stramoniumE. Solanum dulcamara

172. Bacca fruit is typical for the followingrepresentative of Solanaceae family:

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A. Atropa belladonnaB. Hyoscyamus nigerC. Datura stramoniumD. Nicotiana tabacumE. Datura innoxia

173. A patient was found to have anincrease in total bilirubin concentrationin plasma at the expense of indirect bi-lirubin; high rate of stercobilin in fecesand urine; normal rate of direct bilirubin.What jaundice is it?

A. HaemolyticB. MechanicC. Gilbert’s syndromeD. ParenchymatousE. Physiological

174. A patient has been administeredL-carnitine. This preparation ensurestransmembrane transfer of the followingsubstances:

A. Higher fatty acidsB. Amino acidsC. Purine nucleotidesD. Pyrimidine nucleotidesE. Glucose

175. Coordination number of iron inthe potassium hexacyanoferrate (II)K4[Fe(CN)6] is:

A. 6B. 2C. 4D. 3E. 8

176. A patient is 50 years old. Ad a resultof continuous improper feeding he gothypovitaminosis C. Lesion of connecti-ve tissue is caused by low activity of thefollowing enzyme:

A. Proline hydroxylaseB. Alanine aminotransferaseC. Pyruvate carboxylaseD. Tryptophane hydroxylaseE. Glutaminase

177. Low rate of vitamin B6 in the dietaryintake leads to disturbance of proteinmetabolism. What biochemical processesin the patient’s organism will become lessactive?

A. TransaminationB. Reduction-oxidationC. PhosphorilationD. MethylationE. Hydrolysis

178. Before diving experienced divers firsttake several deep breaths. They do it inorder to:

A. Remove as much as possible CO2

B. Reduce functional residual capacity oflungsC. Increase lung vital capacity (LVC)D. Increase total lung capacity (TLC)E. Increase respiratory volume (RV)

179. As a result of reaction of mercuryexcess with diluted nitric acid the followi-ng gas will escape:

A. NOB. NH3

C. N2

D. N2OE. -

180. A 47-year-old patient with an arminjury was delivered to a hospital in painshock condition. Objectively: the pati-ent is in grave condition, with mentalconfusion; integuments are moist, pale,acrocyanotic. There are also tachypnea,fall in the arterial pressure, tachycardia.What type of hypoxia is prevailing in thispatient?

A. CirculatoryB. HaemicC. TissueD. RespiratoryE. Substrate

181. A patient suffering from the essenti-al hypertension presents with an increasein the arterial pressure up to 180/110 mmHg; dyspnea, cyanosis, tachycardia; heartborders are dilated to the left, in lungsmoist rales are present. What signs ofurgent compensation for cardiac failureare observed?

A. TachycardiaB. Arterial pressure riseC. CyanosisD. DyspneaE. Myogenic dilatation

182. A patient has been suffering from di-abetes mellitus for 10 years. He was deli-vered to a hospital in grave condition.On the 2nd day of treatment his condi-tion grew significantly worse: he lapsed

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into a coma, there appeared noisy deepbreathing. Deep inspirations took turnswith forced expirations with assistance ofexpiratory muscles. What form of respi-ration disorder is it?

A. Kussmaul’s respirationB. Stenotic respirationC. TachypneaD. Cheyne-Stokes respirationE. Biot’s respiration

183. The product of potassiumpermanganate reduction in the neutralmedium has the following chemicalformula and colour:

A. MnO2, brownB. MnO2, greenC. K2MnO4, greenD. K2MnO4, violetE. MnSO4, colourless

184. What is maximal valency of ni-trogen in consideration of donor-acceptormechanism of covalent bond?

A. 4B. 1C. 2D. 3E. 5

185. Microscopy of a leaf epidermisof Convallaria majalis showed that thestomata had four accessory cells. Two ofthem were lateral, and two other werepolar. What type of stomatal mechanismis it?

A. TetracyticB. DiacyticC. AnisocyticD. AnomocyticE. Paracytic

186. Medical examination of a dairymaidrevealed affection of the locomotivesystem, vision impairment, disorder of thenervous and other systems. To confirm thediagnosis the patient was referred for aserological assay (Wright’s reaction) andBurnet’s skin allergy test. What was theprovisional diagnosis?

A. BrucellosisB. TularemiaC. AnthraxD. RheumatismE. Leptospirosis

187. Specify the number of degrees offreedom for intersection of the liquidus

line with ordinate axis of the equilibriumdiagram of a two-component system:

A. С = 0B. С = 2C. С = 1D. С = –1E. С = 3

188. After taking phenacetin a pati-ent complained about sore throatand impossibility of deglutition. Anotolaryngologist made a dignosis ofnecrotic angina. In blood: Hb- 130 g/l,erythrocytes - 4, 5 · 1012/l, leukocytes -3, 0 · 109/l, among them lymphocytes -75%, neutrophils - 10%, eosinophils - 5%,monocytes - 10%. What type of whiteblood cell disorder is it?

A. NeutropeniaB. NeutrophiliaC. MonocytosisD. EosinophyliaE. Lymphopenia

189. 3 years ago a patient was diagnosedwith chronic glomerulonephritis. The pati-ent has got multiple edemata within thelast 6 months. What is the cause of theirdevelopment?

A. ProteinuriaB. HyperaldosteronismC. Injection of non-steroidal anti-inflammatory preparationsD. Glucocorticoid treatmentE. Vasopressin hyperproduction

190. One of the herbarium specimens ofmedicinal plants relates to the Asteraceaefamily. This plant is:

A. Arctica lappaB. Atropa belladonnaC. Cassia acutifoliaD. Urtica dioicaE. Rubus idaeus

191. Examination of a medicinal herbrevealed that its leaves were divided downto the base of the leaf blade with segmentsradiating from a common point in a fanmanner. These leaves are:

A. PalmatisectedB. PinnatisectedC. PalmatipartiteD. PinnatipartiteE. Palmatilobate

192. What is the primary standard forstandardization of Hg2(NO3)2 solution?

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A. Sodium chlorideB. Sodium bromideC. Sosium sulphateD. Sodium hydroxideE. Sodium dichromate

193. After the diluted solution ofhydrochloric acid had been added to thesolution under examination, the whitecaseous precipitate settled down. Thisindicates presence of the following ions:

A. SilverB. AmmoniumC. Iron (II)D. BariumE. Iodine

194. Tritane relates to:

A. Multinuclear arenes with isolatedbenzene cyclesB. Multinuclear arenes with condensatedbenzene cyclesC. Mononuclear arenesD. AlkanesE. Alkenes

195. Name the process characterizedby a chemical interaction between anadsorbate and an adsorbent:

A. Chemical adsorptionB. SolvationC. AbsorptionD. DesorptionE. Sedimentation

196. Optical isometry can be applied tothe following compounds:

A. Iodine fluorochloromethane (CHIFCl)B. Methane (CH4)C. Chloroform (CHCl3)D. Dichloromethane (CH2Cl2)E. Tetrachloromethane (CCl4)

197. What analytical effect is observedwhen potassium cation is being determi-ned by the sodium hexanitrocobaltate(III) solution?

A. Yellow crystalline precipitateB. White crystalline precipitateC. Yellow colouring of the solutionD. Black crystalline precipitateE. Red crystalline precipitate

198. Epidemic of influenza wasannounced in a town. Which drug canbe recommended for the nonspecificprophylaxis of influenza?

A. Leukocytic interferonB. Anti-influenza vaccineC. AntibioticsD. Anti-influenza immunoglobulinE. Anti-influenza serum

199. A drug solution under examinationcontains cations of magnesium (II) andaluminium (III). Which reagent can helpto separate these cations during analysisof this drug?

A. Alkali solutionB. Solution of hydrogen peroxide in acidicmediumC. Solution of silver nitrateD. Ammonia solutionE. Solution of chloride acid

200. Quantitative determination ofpharmaceutical substances can be carri-ed out by method of alkalimetry using 0,1M sodium hydroxide solution as a titrant.Precise concentration of sodium hydroxi-de can be determined according to:

A. Oxalic acidB. Sodium tetraborateC. Potassium dichromateD. Sodium thiosulphateE. Ammonium hydroxide