Krok 1 - 2011 Question Paper (Pharmacy)

Krok 1 Pharmacy 2011 1

1. A man got an injection of curareli-ke substance causing the relaxation of allskeletal muscles. What is its mechanism ofaction?

A. Block of cholinergic receptors ofpostsynaptic membraneB. Disturbance of acetylcholine synthesisC. Block of Ca2+-channels of presynapticmembraneD. Disturbance of cholinesterase synthesisE. Disturbance of acetylcholine secretion

2. Production of primary urine in kidneysis induced by filtration in renal corpuscles.What components of blood plasma areabsent in the primary urine?

A. ProteinsB. Amino acidsC. GlucoseD. UreaE. Ions

3. Microscopic examination of primarycortex of a root in its absorption zonerevealed that it consisted mainly ofmultilayer loose living parenchyma withamyloid granules. It is called:

A. MesodermB. EndodermC. ExodermD. CollenchymeE. Phellogene

4. Particles of dispersed phase of anemulsion are deformed and look likepolyhedrons. What emulsion is it?

A. High-concentratedB. ConcentratedC. DilutedD. Oil-in waterE. Water-in-oil

5. A child with evident hypotrophy gotedemata on his lower extremities, asci-tes. What is the main mechanism ofpathogenesis of cachectic edema?

A. Drop of oncotic pressure of bloodplasmaB. Rise of hydrostatic blood pressureC. Rise of oncotic pressure of intercellularfluidD. Increased permeability of vascular wallE. Disturbance of lymph outflow

6. Protein digestion in the stomach iscarried out by pepsin secreted in formof an inactive pepsinogen. Pepsinogen isconverted to pepsin by the removal of the

N-terminal peptide that is provoked by:

A. Perchloric acidB. Sulfuric acidC. Acetic acidD. Bile acidsE. Amino acids

7. Hydrogen is characterized by thefollowing oxidation rates: −1; 0; +1. The−1 oxidation rate hydrogen has in:

A. HydridesB. AcidsC. HydroxidesD. WaterE. Acid salts

8. High-grade deficit of the ascorbic acidcauses development of scorbutus. Thispathology develops due to the disturbedsynthesis of the following connective ti-ssue protein:

A. CollagenB. ProthrombinC. FibrinogenD. AlbuminE. Ceruloplasmin

9. Cardiac diseases are treated wi-th cocarboxylase preparation. Thispreparation is the coenzymatic form ofthe following vitamin:

A. B1

B. B6

C. B12

D. CE. P

10. What substance can act as both oxi-dant and reducer in oxidation-reductionreactions?

A. SO2

B. SO3

C. CO2

D. PbO2

E. CrO3

11. Examination of a patient revealedan increase in low-density lipoproteinconcentration in blood serum. The pati-ent can be expected to have the followingdisease:

A. AtherosclerosisB. PneumoniaC. GlomerulonephritisD. Acute pancreatitisE. Gastritis

12. Nitrogen (I) oxide (N2O) is applied for


inhalation narcosis. It is obtained by heati-ng of:

A. NH4NO3

B. NH3

C. Cu(NO3)2

D. NH4OHE. NaNO3

13. For determination of nitrate ions di-phenylamine was added to the soluti-on under examination. The followingchanges were observed:

A. Generation of blue solutionB. Generation of yellow depositionC. Generation of blue depositionD. Generation of brown gasE. Emergence of a typical smell

14. A patient was prescribed a bilepreparation for better digestion of fattyfood. What components of this preparati-on cause fat emulsification?

A. Bile acidsB. Cholesterol and its ethersC. DiglyceridesD. BilirubinglucuronidsE. Bile pigments

15. According to the requirements ofWHO and Pharmacopoeia different drugdosage forms of unsterile preparationsare allowed to have a certain quantityof bacteria and fungi. What quantity ofsaprophytic bacteria and fungi in 1 g (ml)of a peroral preparation will ensure itssafety?

A. 1000 bacteria and 100 mold fungiB. 500 bacteria and 50 mold fungiC. 250 bacteria and 25 mold fungiD. 500 bacteria and 200 mold fungiE. 1500 bacteria and 150 mold fungi

16. Antibiotics can be classified accordi-ng to various principles. According to theaction mechanism cephalosporins relateto the following group:

A. Inhibitors of cell wall synthesisB. Inhibitors of protein synthesisC. Inhibitors of respiratory processesD. Inhibitors of oxidative phosphorilationE. Inhibitors of cytoplasmic membranesynthesis

17. It is known that digestion of proteins,fats and carbohydrates happens due toprotease, lipase and amylase respectively.What digestive juice contains all threeenzyme groups enough for digestion?

A. Juice of pancreasB. SalivaC. Gastric juiceD. BileE. Juice of large intestine

18. Plant pathogenic microorganismsrelate to various groups. Which of themcauses diseases of medicinal plants mostoften?

A. FungiB. VirusesC. BacteriaD. ActinomycetesE. Micoplasma

19. Iodometric determination offormaldehyde in formaline can be doneby the back titration. Iodine surplus is ti-trated with the standard solution of:

A. Sodium thiosulphateB. Sodium nitrateC. Sodium sulphateD. Sodium carbonateE. Sodium phosphate

20. It is required to diminish pump functi-on of patient’s heart. This can be doneby means of blockers of the followingmembrane cytoreceptors:

A. β-adrenoreceptorsB. Nicotinic cholinoreceptorsC. Muscarinic cholinoreceptorsD. α-adrenoreceptorsE. Dopamine receptors

21. Electrolyte solutions are medicinalpreparations. What is the maximum valueof isotonic coefficient for MgSO4 soluti-on?

A. 2B. 4C. 3D. 5E. 7

22. A patient had cerebral haemorrhagethat made impossible active motions ofleft arm and leg. Muscle tone of theselimbs is increased, their spinal reflexesare intensified, reflex zones are increased.What type of CNS disorder is it?

A. Central paralysisB. Peripheral paralysisC. Spinal shockD. Atonic paralysisE. Reflex paralysis


23. Corolla of the origanum flower iszygomorphic, sympetalous and consists ofa tube and two limbs. The upper limb isbilobate and the lower is trilobate. Suchcorolla is called:

A. BilabiateB. UnilabiateC. LingulateD. Thimble-likeE. -

24. Structure of proteins includes protei-nogenic amino acids. What is the positi-on of the amino group in the structure ofthese amino acids?

A. α-positionB. β-positionC. γ-positionD. δ-positionE. ε-position

25. Biochemical function of water-solublevitamins depends on their ability to turninto the coenzymatic forms. Specify thecoenzymatic form of the vitamin B2 (ri-boflavin):

A. FMN (flavin mononucleotide)B. NAD+ (nicotinamide adenine di-nucleotide)C. TMP (thiamine monophosphate)D. TDP (thiamine diphosphate)E. PALP (pyridoxal phosphate)

26. A plant has ribbed and hollow stems,sheathing pinnatisected leaves; compoundumbel inflorescence; fruit with essentialoil tubules. These features are typical forthe representatives of the following fami-ly:

A. ApiaceaeB. SolanaceaeC. FabaceaeD. BrassicaceaeE. Scrophulariaceae

27. One of the examined soft fruits ischaracterized by essential-oil exocarp,spongioid mesocarp and overgrownendocarp that consists of juice saccules.What fruit was under examination?

A. HesperidiumB. PepoC. MulticoccusD. DrupeE. Bacca

28. Enzymes (biological catalysts) areused as pharmacologic preparations.

What is the mechanism of enzyme acti-on in the biochemical reactions?

A. They reduce the energy of reactionactivationB. They increase the energy of reactionactivationC. They inhibit the reaction processD. They change the constant of the reacti-on rateE. They change the reaction order

29. Depressurization of the cabin at analtitude of 19 km led to instantaneousdeath of pilots. What is its cause?

A. Explosive decompressionB. HematencephalonC. Myocardial infarctionD. BleedingE. Respiratory centre paralysis

30. After a girl had accidentally eateninedible mushrooms she was admittedto the resuscitation unit with symptomsof impaired consciousness, arterialhypotension, anuria, hyperazotemia.What kind of renal dysfunction is it?

A. Acute renal failureB. Acute glomerulonephritisC. Acute pyelonephritisD. UrolithiasisE. Urine acid diathesis

31. Filter paper impregnated with solutionof cobalt (II) nitrate and a solution underexamination forms blue ash when burneddown. This is the evidence of presence ofthe following ions:

A. Al3+

B. Cr3+

C. Ni2+

D. Sb3+

E. Zn2+

32. After a solution had been heated wi-th (NH4)2S2O8 in presence of AgNO3, itturned crimson. What ions were presentin the solution?

A. Mn2+

B. Fe3+

C. Fe2+

D. Co2+

E. Cu2+

33. A solution under examinationwas added to the solution of FeSO4

in presence of concentrated H2SO4.Formation of a brown ring indicatespresence of:


A. Nitrate ionsB. Acetate ionsC. Carbonate ionsD. Oxalate ionsE. Phosphate ions

34. For tuberculosis prevention thenewborns got an injection of a vaccine.What vaccine was used?

A. BCGB. MantouxC. DTaP vaccineD. AnatoxinE. Oral polio vaccine (Sabin vaccine)

35. Bromination proceeds with generationof tribromoderivative in presence of thefollowing substituent X:

A. Х = OHB. Х = COOHC. Х = NO2

D. Х = CHOE. Х = SO3H

36. Gastric juice of a patient has decreasedconcentration of enzymes. What secretorycells of stomach display disfunction?

A. Chief cells of glandsB. Parietal cells of glandsC. Gland mucocytesD. Cells of tegumental epitheliumE. G-cells

37. Yield of medical products canbe enhanced by proper choice oftemperature conditions during theirproduction. What equation determinesdependence of equilibrium constant fromthe temperature under constant pressure?

A. Isobaric lines of chemical reactionB. Isotherms of chemical reactionC. Kirchhoff equationD. Isochores of chemical reactionE. Gibbs-Helmholtz equation

38. During identification of a perennialherb of Ranunculaceaе family it was foundto have: apical flowers of regular form

up to 6 cm in diameter; 5 downy violet-and-green calyx lobes of irregular serrateform; up to 20 bright yellow glossy petalswithout nectarostigma. What plant is it?

A. Аdonis vernalisB. Helleborus purpurascensC. Ranunculus acrisD. Delphinium elatumE. Aconitum napellus

39. A herb under analysis relates tothe Malvaceae family and is used as anexpectorant and coating agent. The stemis erect, with simple palmate three to fivelobed leaves, large pink flowers growing inshort panicles. The herb has schizocarpicfruit - a capsule. Identify the plant:

A. Althaea officinalisB. Fragaria vescaC. Potentilla erectaD. Tussilago farfaraE. Thymus serpyllum

40. What is the final product of methanechlorination?

A. TetrachloromethaneB. ChloroformC. ChloroethanolD. EthaneE. Chloromethane

41. 1M sulphuric acid solution was addedto the solution under study. This resultedin formation of white sediment that wassoluble in the alkalies. This indicated thatthe solution contains:

A. Plumbum cationsB. Calcium cationsC. Barium cationsD. Argentum cationsE. Mercury (I) cations

42. A solution contains cations of zincand aluminum. Specify the reagent thatenables to detect cations of zinc in thissolution:


A. Potassium hexacyanoferrate (II) soluti-onB. Sodium hydroxide solutionC. Cobalt nitrate Co(NO3)2

D. The excess of 6M sodium hydroxide inpresence of hydrogen peroxideE. Sulfuric acid solution

43. The polarographic method iscommonly used for the analysisof inorganic cations and anions.Electroreduction of the analyzed ions isperformed by using:

A. Dropping mercury electrodeB. Platinum electrodeC. Antimony electrodeD. Calomel electrodeE. Silver electrode

44. What disorder of local circulation ischaracterized by pallor, local temperaturedrop, pain, local sensitivity disorder,reduction in the volume of the organ?

A. IschemiaB. VenostasisC. ThrombosisD. EmbolismE. Arterial hyperemia

45. Choose the reagent that can be usedfor acetone cyanohydrin production:

A. HCNB. H2N�OHC. H2N�NH2

D. H2N − NH − C6H5

E. H2N − CH3

46. Which reagent allows to distinguishpropine (CH3 − C ≡ CH) from propene(CH3 − CH = CH2)?

A. [Ag(NH3)2]OHB. Br2

C. HClD. Cu(OH)2

E. Cl2

47. What compound is formed as a resultof reaction:

A.

B.

C.

D.

E.

48. Cellular and plasma mediators playan important part in the pathogenesis ofsecondary alteration during inflammati-on. What mediators are produced in theblood plasma?

A. BradykininB. HistamineC. LeukotrienesD. ProstaglandinsE. Lysosomal factors

49. A 73-year-old patient had been admi-tted to a hospital with closed fracture ofhis right femur. Suddenly his conditiondeteriorated, the patient was diagnosedwith vascular embolism. What type ofembolism is observed most often in pati-ents with the fractures of tubular bones?

A. FattyB. AirC. TissueD. RetrogradeE. Gas

50. Stable contraction of myofibrillaof muscle fibers takes place due toaccumulation of the following ions in thecytoplasm:


A. CalciumB. PotassiumC. SodiumD. MagnesiumE. Hydrogen

51. A 45-year-old woman has frequentuterine haemorrhages, she presents withgeneral weakness, dyspnea, tachycardia,cardiac pain. In blood: erythrocytes -3 · 109/l, Hb- 70 g/l, colour index - 0,7.The smear contains mostly hypochromicerythrocytes, microcytes. Specify the typeof anaemia accrding to its mechanism ofdevelopment:

A. Iron-deficiencyB. B12-folate-deficiencyC. HaemolyticD. Minkowsky-Shauffard diseaseE. Protein-deficiency

52. For production of phenol ether it isnecessary to cause reaction of sodiumphenoxide with:

A. CH3ClB. CH3OHC. CH4

D. CH3NH2

E. CH3C ≡ N

53. Polysaccharide cellulose consists of theremains of the following monosaccharide:

A. β-D-glucopyranoseB. α-D-glucopyranoseC. β-D-fructopyranoseD. α-D-fructofuranoseE. β-D-glucofuranose

54. A higher avascular plant shows clearalternation of generations with the domi-nant sexual (gametophyte) and reduced

asexual (sporophyte) generation. Thisindicates that the plant relates to the:

A. BryophytaB. LycopodiophytaC. EquisetophytaD. PteroidE. Gymnosperms

55. A patient has a necrotizing phlegmonof his lower extremity. A doctor suspectsa gas gangrene. Microscopy reveals gram-positive bacilli. In order to confirm thediagnosis further bacteriological testsshould include inoculation of the materialinto the following nutrient medium:

A. Kitt-Tarozzi mediumB. Endo agarC. Levine agarD. Meat-peptone agarE. Milk-salt agar

56. A female patient bitten by a stray dogcame to a surgery. Wide lacerated woundswere localized on the patient’s face. Whattreatment-and prevention aid should berendered in order to prevent rabies?

A. Immunization with the antirabic vacci-neB. Combined antibiotic therapyC. Hospitalization, injection of diphtheria-pertussis-tetanus vaccineD. Hospitalization, medical surveillanceE. Urgent injection of normal gamma-globulin

57. With an attachment of −CH2 group toa hydrocarbon radical the surface activityof surfactants increases (maximally) by:

A. 3,5 timesB. 2,5 timesC. 1,5 timesD. 4,5 timesE. 5,5 times

58. Specify two compounds that can bepresent in a solution at the same time:

A. Al(NO3)3 and HClB. Ba(OH)2 and CO2

C. NaOH and P2O5

D. CuSO4 and BaCl2E. AgNO3 and HCl

59. Specify the standardized solutionsused for direct and back titration ofreducing agents in the iodometric method:


A. I2, Na2S2O3

B. K2Cr2O7, Na2S2O3

C. I2, KID. KMnO4, KIE. K2Cr2O7, I2

60. Specify the standard solution (titrant)for the iodometric determination of oxi-dants:

A. Na2S2O3

B. KMnO4

C. I2

D. K2Cr2O7

E. KBrO3

61. In a surgical unit an outbreakof purulent infections has been regi-stered. The infections are caused byStaphylococcus aureus with multiple resi-stance to antibiotics. What plasmid hasprovided this property?

A. RB. FC. ColD. ToxE. Hly

62. Iron (II) sulfate is a part of drugs usedin treatment of iron deficiency anemia.FeSO4 enters into reaction with one ofthe following compounds:

A. KMnO4

B. HClC. CO2

D. FeCl2E. NaCl

63. Treatment of a wound with hydrogenperoxide is accompanied by the release ofsome gas bubbles from the solution. Whatkind of gas is it?

A. OxygenB. HydrogenC. OzoneD. Carbon dioxideE. Nitrogen

64. Micelle solutions of surfactants areapplied in pharmaceutical production asstabilizers and solubilizers. What soluti-on of colloidal surfactants will have thegreatest value of critical concentration ofmicelle formation?

A. C9H19SO3NaB. C14H29SO3NaC. C16H33SO3NaD. C12H25SO3NaE. C10H21SO3Na

65. In the pharmaceutical industry, themicelle-forming solutions of surface-active substances are used for producti-on of water-soluble preparations out ofwater-insoluble substances, for examplevitamins A and E. The critical concentrati-on of micelle formation has the lowestvalue in the solutions of the followingsubstances:

A. C17H35COONaB. C12H25COONaC. C13H27COONaD. C15H31COONaE. C11H23COONa

66. Pharmaceutic preparation collargol isa colloid silver solution containing a high-molecular compound. What is the functi-on of this compound?

A. It enhances aggregative stabilityB. It induces coagulationC. It facilitates sedimentationD. It reduces aggregative stabilityE. It increases dispersion degree

67. What kind of standard solution (ti-trant) is used according to Folgard’s directtitration method?

A. Ammonium thiocyanateB. Sodium chlorideC. Silver nitrateD. Potassium chromateE. Potassium dichromate

68. Presence of which ion of d-elements inthe solutions can be detected by means ofK4[Fe(CN)6]?

A. Fe3+

B. Fe2+

C. Zn2+

D. Cr3+

E. Cu2+

69. Temporary hardness of water is causedby presence of the following calcium andmagnesium salts in the natural water:

A. Hydrogen carbonateB. SulfatesC. ChloridesD. NitratesE. Phosphates

70. Which of these chemical substancesCANNOT act as an excitatoryneurotransmitter in the central nervoussystem?


A. GlycineB. SerotoninC. NoradrenalineD. Substance PE. Dopamine

71. Which of the following presentationscan be explained by the functional effectsof adrenaline?

A. Relaxation of bronchial musclesB. The decrease in heart rateC. Dilatation of the skin vesselsD. Intensification of stomach and intesti-nes contractionE. High uropoiesis

72. To quantify the adsorption at the solid-gas interface, the following equation canbe used:

A. FreundlichB. GibbsC. ShishkovskiD. Helmholtz-SmoluchowskiE. Rayleigh

73. Iron (III) hydroxide is produced as aresult of interaction of:

A. FeCI3 with NaOHB. Fe2O3 with NaOHC. FeCI3 with H2OD. Fe2O3 with H2OE. Fe with NaOH

74. What compound is formed as a resultof the intermolecular dehydration ofethanol?

A. C2H5 − O − C2H5

B. C2H5 − O − SO3HC. CH2 = CH2

D.

E.

75. As a result of the reaction of cyclic

forms of monosaccharides with alcoholsin presence of an acid catalyst the followi-ng compounds are formed:

A. GlycosidesB. EstersC. OsazonesD. AcidsE. Oxoacids

76. During examination of a plant cellunder the electron microscope somestructures in form of a stack of flattenedmembrane cisterns and vesicles werefound. What organelles are these?

A. Golgi apparatusB. Endoplasmic reticulumC. PlastidsD. MitochondrionsE. Microbodies

77. Analysis of the cerebrospinal fluid ofa child with signs of purulent lesion ofbrain tunics revealed gram-negative bean-shaped diplococci. What presumptive di-agnosis can be made on the basis of theanalysis results?

A. MeningitisB. GonorrheaC. CholeraD. PlagueE. Anthrax

78. As a result of the interaction of excessalkali with amphoteric metals the followi-ng compound is formed:

A. Hydroxo complexesB. OxidesC. HydroxidesD. Neutral saltsE. Basic salts

79. Chlorophyll, the green pigment ofplants, is a chelate compound. Specify the


chelating ion in chlorophyll:

A. Mg2+

B. Fe3+

C. Mn2+

D. Fe2+

E. Ni2+

80. In order to enhance the solubility ofthe individual components of a numberof liquid drug formulations, the colloidalsurface-active substances are added. Whatphysico-chemical phenomenon underliesthis process?

A. SolubilizationB. CoagulationC. ExtractionD. DiffusionE. Sedimentation

81. A flower has the androecium consisti-ng of two long and two short stamens.Therefore the flower’s androecium is:

A. DidynamousB. TetradynamousC. DiadelphousD. TetradelphousE. Polyadelphous

82. Potassium dichromate K2Cr2O7 isapplied as an oxidant in acidic medi-um. What is the product of reductionof dichromate-ion Cr2O

2−7 under these

conditions?

A. Cr3+

B. Cr(OH)3

C. Cr(OH)2

D. [Cr(OH)6]3−

E. Cr2O3

83. Mass serological diagnosis of HIVinfection is made by means of enzyme-linked immunosorbent assay techniques.What standard component of the reactionmust be adsorbed on the solid phase ofthe test system?

A. HIV antigensB. Monoclonal HIV antibodiesC. Enzyme-marked HIV antibodiesD. Specific immunoglobulinsE. Substrates to determine enzyme activity

84. What compound will be producedduring reduction of methyl ethyl ketone?

A. secondary-butyl alcoholB. Butanol-1C. Isobutyl alcoholD. tertiary-butyl alcoholE. Propanol-2

85. What medication is formed as a resultof interaction of salicylic acid with aceticanhydride?

A. AspirinB. Salicyl amideC. Phenyl salicylateD. Benzyl salicylateE. Sodium salicylate

86. Digestion of proteins in the digesti-ve tract is a complex process of theirhydrolysis till peptides and free amino aci-ds. What enzymes decompose proteins inthe duodenum?

A. Trypsin, chemotrypsinB. Enterokinase, lipaseC. Amylase, maltaseD. Pepsin, gastricsinE. Lipase, phospholipase

87. After a 5-year-old child has beenbrought home from the kindergarten hepresented with weakness, headache, bodytemperature rise up to 37, 5oC. What peri-od of disease develompent is the case?

A. ProdromalB. LatentC. IncubativeD. RecoveryE. Fastigium

88. Iodimetry involves use of standardsolutions of iodine and Na2S2O3. Whatsubstance is used to standardize the sodi-um thiosulfate solution?


A. K2Cr2O7

B. NaClC. N2B4O7

D. K2CO3

E. As2O3

89. It is required to determine the amountof sodium salicylate in a solution. What ti-trimetric method can be applied for thequantitative determination of aromaticcompounds?

A. BromometryB. MercurimetryC. CerimetryD. ArgentometryE. Chelatometry

90. A 56 year-old patient complains aboutlimitation of movements and pain inhand joints, mainly at night. Objectively:there is a disfiguring painful swelling ofaffected joints. Blood and urine have highconcentration of uric acid. What diseasehas developed?

A. GoutB. PellagraC. PhenylketonuriaD. AlkaptonuriaE. Tyrosinosis

91. What elements of IIB group exhibitamphoteric properties?

A. Zinc onlyB. Zinc and cadmiumC. Cadmium and mercuryD. All elementsE. Mercury only

92. Interaction of aniline with of brominewater resulted of white precipitate. Whatsubstance was produced?

A.

B.

C.

D.

E.

93. Analytical indication of effect ofpotassium iodide solution upon unstai-ned oxidizing anions in presence ofchloroform is:

A. Brown stain of free iodineB. Settling down of white depositionC. Change of aggregate stateD. Emission of gas bubblesE. Origination of deposition and its soluti-on in reagent excess

94. Every year during the plant blossomi-ng a female patient develops acutecatarrhal inflammation of conjuncti-va and nasal mucosa that is the cli-nical presentation of an allergy. Thesesymptoms relate to the following type ofallergic reactions:


A. AnaphylacticB. CytotoxicC. Immune complexD. Cell-mediatedE. Cellular dysfunction

95. A female patient consulted a doctorabout leg pain that arises usually towardthe evening; feet and shins edemata.Objectively: leg skin is cyanotic, cold tothe touch. What type of peripheral ci-rculation disorder does the patient presentwith?

A. Venous hyperaemiaB. Arterial hyperaemiaC. IschaemiaD. StasisE. Thrombosis

96. Presence of the pathogenic mi-croorganisms in the air can be prognosti-cated according to the content of sanitary-indicative bacteria. Which bacteria indi-cate immediate epidemiologic danger?

A. Haemolytic streptococciB. SarcinaeC. Mold fungiD. Yeast fungiE. Micrococci

97. A patient with low immunity, frequentcolds is recommended to take ascoruti-ne as a more effective drug than ascorbicacid. What constituent substance of thispreparation intensifies action of vitaminC?

A. Vitamin PB. Vitamin AC. GlucoseD. LactoseE. Vitamin D

98. Determination of ∆Boiling poi-nt of water-alcohol mixtures is thepharmacopoeial method of quantitativedetermination of alcohol. Which methodenables to determine ∆Boiling point?

A. EbullioscopyB. CryoscopyC. EnteroscopyD. OsmometryE. Conductometry

99. Toluol is converted to the benzoic acidunder the following conditions:

A. Oxidation with potassiumpermanganateB. Heating with sulphuric acidC. Hydrogen peroxide action at a roomtemperatureD. Sodium hydroxide action at a roomtemperatureE. Boiling in the open air

100. Which of the following compoundsforms a propionic aldehyde as a result ofalkaline hydrolysis (H2O, OH−)?

A.

B.

C.

D.

E.

101. The 0,1 M solution of whi-ch substance has the smallest ionconcentration?

A. CH3COOHB. HClC. CaCl2D. H2SO4

E. NaNO3

102. Inflammatory processes in the gallbladder exert negative influence on thecolloidal properties of bile. This may leadto gallstone formation. One of the causes


of their formation is the crystallization ofthe following substance:

A. CholesterolB. AlbumineC. HaemoglobinD. UratesE. Oxalates

103. Which of the given bases is a weakelectrolyte?

A. Mg(OH)2

B. Ca(OH)2

C. Ba(OH)2

D. NaOHE. KOH

104. Bacteria may contain not onlychromosomal but also nonchromosomalhereditary elements called plasmids.Presence of plasmid genes can show itselfby:

A. Multiple drug resistanceB. Stain resistanceC. Physical factor resistanceD. Sporogenesis abilityE. Mobility

105. The method of "accelerated drugageing"used for determination of drugshelf life is based upon:

A. Van’t Hoff’s ruleB. Fajans’ ruleC. Planck’s postulateD. Ostwald lawE. Raoult law

106. Choose the reagents for detection ofthe sulphate ions in a solution containingcarbonate, sulphate and phosphate ions:

A. Ba(NO3)2, HClB. Ba(NO3)

−2, NaOHC. BaCl2, H2OD. CaCl2, NH4OHE. AgNO3, HNO3

107. Transamination is the biochemicalprocess in which amino groups of differentamino acids take form of one of the aminoacids. What amino acid is it?

A. GlutamicB. GlycineC. ValineD. LeucineE. Arginine

108. Microscopic examination of groundtissue of a small branch revealed cork andfelloderm. These are the derivates of:

A. PhellogenB. CambiumC. ProcambiumD. ProtodermE. Pericycle

109. Chooes the reagent that can be usedfor acylation of amines:

A. (CH3CO)2OB. CH3CHOC. C2H5ClD. HNO2

E. CHCl3 + NaOH

110. What type of tautomerism is typicalfor the given compound?

A. Nitro-aci-nitro tautomerismB. Carbonyl-enol tautomerismC. Cyclo-oxo tautomerismD. Amine-imine tautomerismE. Keto-enol tautomerism

111. Aminotransferases are the enzymesthat transfer an amino group from onecompound to another. What compound isthe acceptor of amino groups?

A. α-ketoglutaric acidB. AcetoneC. Lactic acidD. Succinic acidE. Butyric acid

112. Alpha-cells of pancreas stimulatesynthesis of the glucagon hormone that isinvolved into the carbohydrate metaboli-sm. It has the following effect on liverprocesses:


A. Activates glycogenolysisB. Activates alcoholic fermentationC. Inhibits glycogenolysisD. Inhibits glycolysisE. Activates lypogenesis

113. Sol Al(OH)3 was produced as a resultof treatment of freshly prepared Al(OH)3

precipitate with a small amount of HClsolution. What phenomenon underlies thesol production?

A. Chemical peptizationB. Chemical condensationC. Washing with a solventD. Mechanical dispersionE. Physical condensation

114. What is oxidation number of thecentral atom in the compound H [AuCl4]?

A. +3B. 0C. +1D. +2E. +4

115. A 37-year-old man was admittedto a hospital with an attack of bronchi-al asthma. What respiration type will beobserved in this patient?

A. Expiratory dyspneaB. Inspiratory dyspneaC. ApnoeaD. Gasping respirationE. Hyperpnoea

116. It is required to measure the nitrogenmetabolism in a person under observati-on who is recovering from continuousstarvation. What result is most likely tobe expected?

A. Decrease in nitrogen secretionB. Nitrogen equilibriumC. Negative nitrogen balanceD. AcetonemiaE. -

117. It is required to increase the secreti-on of gastric juice in an experimentaldog with stomach fistula. What should beintroduced into the stomach?

A. Meat brothB. White breadC. MilkD. Dried breadE. Sour cream

118. Anti-tetanus gamma globulin isproduced by hyperimmunization ofdonors with tetanus anatoxin. What

class of immunoglobulins prevails in thispreparation?

A. IgGB. IgAC. IgMD. IgEE. IgD

119. Specify the product that results fromthe interaction of 2 moles of HCl with 1mole of propyne:

A.

B.

C.

D.

E.

120. Specify the name of the compoundaccording to the IUPAC nomenclature:

A. 2,3,5-Trimethyl heptadiene-3,4B. 3,5,6,6-Tetramethyl heptadiene-3,4C. 3,5,6,6-Trimethyl hepten-3D. 2-Ethyl-4,5-dimethyl hexadiene-2,3E. 2-Ethyl-4,5,5-trimethyl pentadiene-2,3

121. Which salt should be dissolved inwater in order to increase the concentrati-on of hydrogen ions?


A. ZnCl2B. NaNO3

C. KClD. Na3CO2

E. Na2S

122. Drugs in form of colloidal-and-disperse systems are widely spread in thepharmaceutical practice. What methodof sol production is based upon thephenomenon of physical condensation?

A. Solvent substitutionB. ReductionC. OxidationD. HydrolysisE. Double exchange

123. Under what conditions the limitedswelling of gelatine turns into the unlimi-ted one?

A. HeatingB. CoolingC. In presence of PO3−

4 ionsD. In presence of Cl− ionsE. In presence of H+ ions whoseconcentration is equal to their concentrati-on in the isoelectric point

124. As a result of staining of a plant mi-croslide with Sudan III solution the cellmembranes turned pink. This indicatesthe presence of:

A. SuberinB. CelluloseC. LigninD. PectinE. Hemicellulose

125. Choose a pair of titrants for the quali-tative determination of ammonia in asolution by the method of back titration:

A. HCl, NaOHB. HCl, H2SO4

C. KOH , NaOHD. NaOH , KClE. H2SO4, K2SO4

126. The analytical effect of reaction ofpotassium hexacyanoferrate (II) solutionwith iron (III) ions is:

A. Formation of blue precipitateB. Formation of white precipitateC. Formation of blue precipitate and itsdissolution in the excess of the reagentD. EffervescenceE. Characteristic smell

127. Content of potassium dichromate in

a solution was determined by iodometricmethod. Name the titrant of iodometricmethod for oxidant determination:

A. Sodium thiosulfateB. Sodium hydroxideC. Potassium iodideD. Potassium permanganateE. Potassium bromate

128. Under anaerobic conditions duri-ng glycolysis ATP is synthesized bythe way of substrate phosphorylation.This process uses energy of other high-energy compounds. Specify one of suchcompounds:

A. Phosphoenol pyruvateB. Glucose 6-phosphateC. LactateD. PyruvateE. Glucose

129. Fruits of the Apiaceae family canbe identified on the basis of a set ofmorphological features and presence ofthe following formation in the pericarp:

A. Essential oil tubulesB. Resin ductsC. Articulated lacticifersD. Non-articulated lacticifersE. Wax strips with stomata

130. A patient was diagnosed with ri-ght lung cancer and doctors administeredhim surgical treatment. After right-sidedpulmonectomy the patient began to sufferfrom evident dyspnea. What form of respi-ratory failure is it?

A. Pulmonary restrictiveB. CentralC. PeripheralD. Pulmonary obstructiveE. Thoracodiaphragmal

131. During the practical training thestudents placed the isolated frog’s heartinto a solution. This caused the cardiacarrest in diastole. What solution was theheart placed into?

A. 3% solution of KClB. 1% solution of NaClC. 3% solution of NaClD. 1% solution of CaCl2E. 0,1% solution of MgCl2

132. A patient takes blocker of muscari-nic cholinoreceptors of parasympatheticnerve organ synapses. What changes ofheart activity will be observed?


A. Heart rate riseB. Heart rate and heart force fallC. Heart rate fallD. Heart force fallE. Prolongation of atrioventricular delay

133. A patient complains about anincrease in heart rate, hyperperspirati-on, irritability, sleeplessness. He has beenpresenting with these symptoms for thelatest six months. They indicate thehyperfunction of the following endocri-ne gland:

A. Thyroid glandB. PancreasC. Adrenal glandsD. Sexual glandsE. Thymus

134. Examination of five herbarium speci-mens of medicinal plants showed that oneof them belonged to the legume family,namely:

A. Glycyrhiza glabraB. Atropa belladonnaC. Hyoscyamus nigerD. Datura stramoniumE. Solanum dulcamara

135. Iron in the +6 oxidation state actsonly as an oxidant because:

A. It is in the maximum oxidation stateB. It has 5 outer shell electronsC. It falls into VIIIB groupD. It is a d-elementE. It is found in the fourth period

136. Before diving experienced divers firsttake several deep breaths. They do it inorder to:

A. Remove as much as possible CO2

B. Reduce functional residual capacity oflungsC. Increase lung vital capacity (LVC)D. Increase total lung capacity (TLC)E. Increase respiratory volume (RV)

137. A woman in labour has been gi-ven a drug that activates contractionsof the smooth muscles of uterus. Whichhormone is a part of this drug?

A. OxytocinB. GastrinC. SecretinD. AngiotensinE. Bradykinin

138. Perchromic acid formed as a resultof chromium oxidation is unstable and di-ssolves in aqueous solutions. What solventis used for its extraction?

A. Isoamyl alcohol and etherB. ChloroformC. BenzeneD. NitrobenzeneE. Ethanol

139. When a smear is stained by Burry-Gins method a mucous structure thatis tightly bound with the cellular wallof bacteria and has well-defined outerboundaries can be detected. This elementof a bacteria cell is called:

A. CapsuleB. SporeC. FilamentsD. RibosomesE. Episomes

140. Sanitary-biologic examination ofair in a drugstore revealed a sanitary-indicative microorganism. Name it:

A. Staphylococcus aureusB. Colon bacillusC. Fecal enterococcusD. Alpha-haemolytic streptococcusE. Citrobacter

141. The product of full acetylation ofglycerol relates to the following class oforganic compounds:

A. EsterB. EtherC. KetoneD. AcetalE. Phenol

142. Specify the number of degrees offreedom of the intersection of liquidus li-ne with the ordinate axis of diagram of atwo-component system state:


A. C = 0B. C = 2C. C = 1D. C = -1E. C = 3

143. What thermodynamic potential isthe criterion for the direction of aspontaneous process at constant volumeand temperature?

A. Helmholtz energyB. EntropyC. Gibbs energyD. Chemical potentialE. Enthalpy

144. A citrus fruit is characterized by theglandular exocarp, spongiose mesocarpand overgrown endocarp consisting of jui-ce sacs. Such fruit is called:

A. HesperidiumB. LegumeC. PodD. DrupeE. Bacca

145. What is the mechanism of brominati-on of toluene aromatic ring?

A. SE

B. AE

C. SR

D. SN

E. AN

146. A patient fell ill the day before, thedisease is acute with a predominance ofgeneral toxic symptoms. With an accountfor the epidemic situation in the city,the doctor diagnosed the patient withinfluenza A. What emergency etiotropictreatment must be administered to thispatient?

A. RimantadineB. Oxolinic ointmentC. GentamicinD. Inactivated influenza vaccineE. Human gamma globulin

147. Specify the reagents enabling to provethe presence of a primary amino groupin a molecule of n-aminobenzoic acid bymeans of isonitrile test:

A. CHCl3, NaOHB. Br2, H2OC. NaHCO3

D. KMnO4

E. I2, NaOH

148. Specify the reaction which proves theacidic properties of phenol:

A. Phenol + sodium hydroxide

B. Phenol + bromine

C. Phenol + nitric acid

D. Phenol + hydrogen

E. Phenol + chloromethane

149. Specify the electronic effects of thecarboxyl group (−COOH) in a moleculeof benzoic acid:

A. −I , −MB. −IC. +I , −MD. +IE. −I , +M


150. Butanol-1 (n-butyl alcohol) and 2-methyl-1-propanol (isobutyl alcohol) arethe isomers:

A. Of carbon chainB. Position isomersC. OpticalD. GeometricE. Of functional group

151. A leaf of a plant under examinati-on has a membranous ochrea wrappedaround the internode base. Presence ofsuch modified stipules is the diagnosticfeature of the following family:

A. PolygonaceaeB. GramineaeC. RosaceaeD. LegumesE. Solanaceae

152. A solution containing the cations ofthe V analytic group (acid-base classifi-cation) has been taken for the analysis.The solution of sodium hydroxostannitehas been added to the composition whichresulted in formation of black depositi-on. This is the evidence of presence of thefollowing cation:

A. Bi3+

B. Fe2+

C. Sb3+

D. Fe3+

E. Mg2+

153. Which of the following adsorbentsis the most effective for adsorption of asubstance from the aqueous solution?

A. Activated carbonB. Silica gelC. QuartzD. Bolus albaE. Gypsum

154. Choose a plant whose apical sproutsare used in medical practice for sedativedrug production:

A. Leonurus cardiacaB. Glycyrrhiza glabraC. Digitalis purpureaD. Ledum palustreE. Fagopyrum sagittatum

155. Examination of procured medicinalherbs grown in a warm climate revealedtheir affection in form of yellowing,overgrowth of lateral shoots, dwarfism,delayed fruiting. Which organisms cancause such changes?

A. MycoplasmaB. VirusesC. BacteriaD. FungiE. Protozoa

156. Molar mass equivalent to bariumhydroxide (M(Ba(OH)2) = 171 g/mol) is:

A. 85,5 g/molB. 34 g/molC. 42,8 g/molD. 57 g/molE. 232 g/mol

157. Sanitary microbiological analysisof the indoor air of a pharmacy carri-ed out in summer revealed presenceof Streptococcus haemolyticus andStreptococcus viridians at the rate of 40microorganisms per 1 m3. Specify the mi-crobiological characteristic of the air:

A. ContaminatedB. Within the permissible limitsC. Almost pureD. PureE. These microorganisms are not thedeterminants of the air quality

158. Each stem node of white deadnettle(Lamium album) has two leaves whichgrow perpendicularly to the leaves of theprevious node. Such leaf arrangement iscalled:

A. Cross-oppositeB. SpiralC. VerticillateD. RosetteE. Leaf mosaic

159. A 3,5-year-old child has been di-agnosed with dysbacteriosis in formof critical reduction of gram-positiveanaerobic bacteria and increased numberof staphylococci and yeast fungi. Whi-ch preparation should be used for thecorrection of dysbacteriosis?

A. BifidumbacterinB. ColibacterinC. Coli-Proteus bacteriophageD. FurazolidoneE. Lactoglobulin

160. One of saliva functions is the bacteri-cidal one. It can be fulfilled due to thefollowing substance:


A. LysozymeB. AmylaseC. BradykininD. MaltaseE. Mucin

161. Morphological analysis of leavesrevealed that each vein runs along thelamina separately and the veins jointogether only at the top of the lamina.This kind of venation is called:

A. ArcuateB. PinnateC. DichotomousD. PalmateE. -

162. During identification of an unknownsalt the colorless part of the burner flameturned yellow and green. What cation wasthe salt formed by?

A. Ba2+

B. Ca2+

C. Sr2+

D. Na+

E. K+

163. A pharmaceutical analyst has toidentify potassium acetate. He can provethe presence of potassium cation in theanalyzed substance by means of thefollowing solution:

A. Tartrate acidB. Sodium hydroxideC. Potassium permanganateD. Iron (III) chlorideE. Formate acid

164. A pharmacist studies the coagulati-on process. He adds the minimumconcentration of the electrolyte to asol. Coagulation takes place when thisconcenration is exceeded. The minimumconcentration of the electrolyte is called:

A. Coagulation thresholdB. Sedimentation thresholdC. Sensitivity thresholdD. The threshold of the adsorption-solvation sensitivityE. Coagulating power

165. Reaction of a group reagent with thecations of the 2nd analytical group resultsin precipitation of PbCl2 which can be di-ssolved in:

A. Hot waterB. 0,2 M solution of sodium carbonateC. Saturated solution of sodium carbonateD. 2M sulfuric acid solutionE. Ethanol

166. A student had analyzed aninflorescence and found out that theflowers on the developed main axis wereset one by one, and due to the vari-ous length of pedicels they were locatedalmost in the same plane, so they formed:

A. CorymbB. GlomusC. AnthodiumD. VoluteE. Umbel

167. A 50-year-old patient complains ofhaving dyspnea under a considerablephysical stress, leg edemata. Examinati-on reveals chronic myocarditis and ci-rculatory failure. What is the evidence ofcardiac decompensation in the patient?

A. Decreased cardiac outputB. Increased blood flow velocityC. Increased vascular resistanceD. Decreased venous pressureE. Increased hydrostatic pressure in thelumen of blood vessels

168. Study of secretory functionof stomach revealed a decrease inhydrochloric acid concentration in gastricjuice. This must cause hypoactivity of thefollowing enzyme:

A. PepsinB. HexokinaseC. AmylaseD. LipaseE. Dipeptidase

169. In order to reduce heart rate duringtachycardia alternative medicine doctorsrecommend to induce artificial vomiting.Specify the efferent nerve of this reflex:

A. VagusB. Glossopharyngeal nerveC. Sympathetic (abdominal) nerveD. HypoglossusE. Phrenic nerve

170. Saffron propagates vegetatively - viacorms which are a modification of . . .


A. Underground shootB. Main rootC. Above-ground shootD. Lateral rootsE. Additional roots

171. Mass fraction of Fe2+ ions in Mohr’ssalt can be determined by gravimetricsedimentation method using:

A. NH4OHB. Na2SC. K3PO4

D. BaCl2E. ZnCl2

172. In order to generate hydrogen bymeans of Kipp’s apparatus the followingreagents should be used:

A. Zinc and diluted sulfuric acidB. Aluminum and potassium chloridesolutionC. Magnesium and concentrated sulfuricacidD. Hydrogen peroxideE. The compound of hydrogen and carbon

173. Specify a halogen whose reaction wi-th hydrogen causes an explosion:

A. FluorineB. BromineC. ChlorineD. AstatineE. Iodine

174. Inhibition of the synthesis of bile aci-ds from cholesterol in liver of an experi-mental animals has caused maldigestionof lipids. What is the role of these acids inthe enteral lipidic metabolism?

A. They emulsify dietary lipidsB. They keep balance of alkaline envi-ronment in the gutC. They participate in the synthesis oflipidsD. They are part of LDLE. They activate the formation of chylomi-crons

175. Pheochromocytoma provokeshypersecretion of adrenaline andnoradrenaline. The concentration of freefatty acids is higher than normal. In thiscase hyperlipidemia is caused by activati-on of the following enzyme:

A. Triglyceride lipaseB. Phospholipase CC. Phospholipase A2

D. Phospholipase A1

E. Glycogen phosphorylase

176. After a 40-year-old patient hadchanged his body position from verticalto horizontal one his heart rate droppedfrom 70 to 65 bpm. This reaction wascaused by the following reflex:

A. Depressor reflexB. Pressor reflexC. Goltz reflexD. Aschner reflexE. Bainbridge reflex

177. The microflora of the colon plays animportant part in the process of digestion.What vitamins does it synthesize?

A. Vitamins K and B groupB. Vitamin CC. Vitamin PPD. Vitamin EE. Vitamin A

178. Styloids are big single elongate-prismatic needle-like crystals. They aremostly typical for the following plants:

A. MonocotyledonousB. DicotyledonousC. GymnospermousD. LycopodiophytaE. Equisetophyta

179. The listed below drugs can be used tocorrect acid-base and ionic balance. Provi-ded that their molar concentration is thesame, the following solution will have themaximum value of ionic strength:

A. Calcium chlorideB. Potassium chlorideC. Potassium iodideD. Sodium chlorideE. Sodium fluoride

180. Examination of a patient revealedan increase in ammonia and citrullineconcentration in blood, a decrease in ureaconcentration in urine as well as citrulli-nuria. This condition is caused by the defi-ciency of the following enzyme:

A. Arginine-succinate synthetaseB. Glutamine synthetaseC. Ornithine carbamoyl transferaseD. GlutaminaseE. Arginine-succinate lyase

181. A patient with atherosclerosis has


been prescribed Linaetholum containi-ng essential fatty acids. Which of thefollowing acids is an obligatory part ofthe preparation?

A. LinolenicB. PalmiticC. CrotonicD. StearicE. Oleic

182. What cation of the 4th analyticalgroup is present in a solution, if it is knownthat the reaction with a group reagentcauses formation of yellow precipitate?

A. Cr3+

B. Zn2+

C. Sn2+

D. Al3+

E. Sn(IV )

183. A patient complains of generalweakness, dyspnea, palpitation. Exami-nation revealed inflammation of themucous membrane of tongue, lips, especi-ally in the corners of mouth; inflammati-on and increased vascularization in theexternal membrane of eye. What is the li-kely cause of this pathological condition:

A. Hypovitaminosis B2

B. Hypovitaminosis AC. Hypovitaminosis CD. Hypervitaminosis AE. Hypervitaminosis B1

184. Examination of a patient revealed anincrease in 17-ketosteroid concentration inurine. Hydroxylation of 17-ketosteroids ispossible with the enzymes of the followingsystem:

A. Microsomal oxidationB. Krebs cycleC. Protein synthesis systemD. Pentose phosphate cycleE. Ornithine cycle

185. It is necessary to carry out preventivevaccination of a student group becauseof an occurrence of diphtheria. Whichpreparation should be used for the creati-on of the artificial active immunity?

A. Diphtheria anatoxinB. Specific immunoglobulinC. DTP vaccineD. Inactivated bacteria vaccineE. Anti-diphtheria serum

186. A patient consulted a doctor aboutintolerance to the sun rays. He presents

with skin burns, impaired vision. He hasbeen diagnosed with albinism. It is causedby the deficiency of the following enzyme:

A. TyrosinaseB. DOPA-oxidaseC. Phenylalanine hydroxylaseD. Ornithine carbamoyl transferaseE. Arginase

187. The properties in a series of oxides:Al2O3 - SiO2 - P2O5 - SO3 - Cl2O7 changein the following way:

A. The properties increase from left torightB. The properties decrease from left torightC. The properties first increase and thendecreaseD. The properties do not changeE. The properties first decrease, thenincrease

188. Select the fruit that meets the descri-ption: monocarpic, dry, polyspermous, canbe split apart only in the ventral suture.The seeds are located along the ventralsuture:

A. FollicleB. CoccusC. Fleshy stone fruitD. Dry stone fruitE. Follicetum

189. A patient with current coronary heartdisease who had had two myocardialinfarctions of left ventricular wall presentswith bubbling breathing and dyspnea.Pulmonary auscultation reveals moistrales. What kind of heart failure is it?

A. Left ventricularB. Right ventricularC. CompensatedD. SubcompensatedE. Combined

190. A healthy 45-year-old man is sitti-ng in a chair reading a newspaper. Whatmuscles ensure breathing in a sitting posi-tion?

A. Diaphragm and external intercostalmusclesB. ScalenesC. Diaphragm and internal intercostalmusclesD. Internal intercostal muscles and straightmuscles of abdominal wallE. Sternocleidomastoid muscles


191. Parents of a 11-year-old boy noti-ced that he is far behind his peers inthe physical development. After the X-ray an endocrinologist revealed that thegrowth zones of tubular bones had alreadyclosed. Under these conditions, the intakeof growth hormone can result in thedevelopment of:

A. AcromegalyB. GigantismC. DwarfismD. CretinismE. Myxedema

192. A 46-year-old patient was found tohave hyperactivity of creatine kinase inblood serum. What kind of pathologyshould be suspected?

A. Myocardial infarctionB. Acute pancreatitisC. Chronic hepatitisD. Haemolytic anemiaE. Renal failure

193. Colloidal dispersion systems includesystems whose particle size is within therange:

A. 10−9 - 10−7 mB. 10−7 - 10−4 mC. > 10−4 mD. < 10−9 mE. 10−9 - 10−4 m

194. Drugs that block certain channelscan prevent the transmission of exci-tation from presynaptic membrane tothe postsynaptic memebrane of synapse.What channels are blocked?

A. CalciumB. SodiumC. Potassium potential-dependentD. Potassium ATP-dependentE. Chlorine

195. A patient with obstructive jaundi-ce presents with bradycardia, low arteri-al pressure, itching, irritability, asthenia.What is the cause of these presentations?

A. CholemiaB. AnacholiaC. HypercholesterolemiaD. HypocholesterolemiaE. Hyperbilirubinemia

196. Humoral immune response to anantigen results in generation of antibodi-es produced by plasmacytes. Plasmacytesarise as a result of immunostimulated di-vision from the following cells of immunesystem:

A. B-lymphocytesB. MonocytesC. GranulocytesD. T-helpersE. T-killers

197. It is known that the leaves ofEucalyptus globulus have cavities withwell-defined internal boundaries and fi-lled with essential oils. They are called:

A. Schizogenous cavitiesB. Non-articulated lacticifersC. Schizolysigenous cavitiesD. Articulated lacticifersE. Lysigenous cavities

198. Examination of a patient revealedtoxic hepatitis developed on thebackground of the use of medicines. Thisdiagnosis can be confirmed by the activityof the following enzyme of blood serum:

A. Alanine amino transferaseB. Creatine phosphokinaseC. Pyruvate dehydrogenaseD. MaltaseE. Malate dehydrogenase

199. A patient has a mental disorder dueto the insufficient synthesis of gamma-aminobutyric acid in the brain. Suchpathological changes might be caused bythe deficiency of the following vitamin:

A. PyridoxineB. TocopherolC. CyanocobalaminD. Folic acidE. Riboflavin

200. How many stages has a system consi-sting of molten salts NaCl and CaCl2,and being in balance with crystals of therespective salts?

A. 3B. 4C. 1D. 2E. The number of phases changes with time

Health & Medicine

Krok 1 - 2011 Question Paper (Pharmacy)