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Intro to ANS DR RAHUL ASSO.PROF

Introduction to Autonomic Nervous System Pharmacology

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Dr Rahul Kunkulol

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Page 1: Introduction to Autonomic Nervous System Pharmacology

Intro to ANSDR RAHUL

ASSO.PROF

Page 2: Introduction to Autonomic Nervous System Pharmacology

The Human Nervous System

Page 3: Introduction to Autonomic Nervous System Pharmacology

What Is It ?

Regulation of blood pressure

Control of visceral smooth muscle(eyes, bladder, bowel)

Control of endocrine and exocrine glands

Control of metabolic energy (glycolysis, neoglucogenesis etc)

ANS Controls

Distribution of blood flow & tissue perfusion

The component of the Nervous System that functions below the conscious level, controlling several key physiological processes

Page 4: Introduction to Autonomic Nervous System Pharmacology

Neurotransmitters

Neurotransmitters Present In Peripheral Nervous System

Acetylcholine Norepinephrine Epinephrine

Neurotransmitters are endogenous chemicals which transmit signals from a neuron to a target cell across a synapse

Definition

Page 5: Introduction to Autonomic Nervous System Pharmacology
Page 6: Introduction to Autonomic Nervous System Pharmacology
Page 7: Introduction to Autonomic Nervous System Pharmacology
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Sympathetic Sympathetic Para-

sympathetic Para-

sympathetic

CholinergicCholinergic Adrenergic Adrenergic

ANSANS

NeurotransmitterNeurotransmitter

Type Of SystemType Of System

Nicotinic & Muscarinic

α1 α2 β1 β2 β3

ReceptorsReceptors

Page 9: Introduction to Autonomic Nervous System Pharmacology
Page 10: Introduction to Autonomic Nervous System Pharmacology

Neurohumoral transmission

Recognition

Release

Storage

Synthesis

Metabolism

5 Steps