23
ECMO in Cardiac Arrest Johnny iliff

ECMO in Cardiac Arrest

Embed Size (px)

Citation preview

Page 1: ECMO in Cardiac Arrest

ECMO in Cardiac Arrest

Johnny iliff

references LITFL Alfred Hospital ECMO Project

What is it ECMO is extra-corporeal membrane oxygenation extracorporeal life support (ECLS) may be a better

term The extracorporeal circuit allows for the

oxygenation and removal of carbon dioxide from blood

used as a supportive strategy in patients who have a high risk of death despite conventional therapy

Why are we considering it in the ED for Cardiac Arrest ldquoPatients with refractory ventricular fibrillation

receiving E-CPR tended to have higher survival rates and significantly improved neurological outcomes when compared with those receiving C-CPRrdquo Managing cardiac arrest with refractory ventricular fibrillation in the emergency department Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation1113088 -Fu-Yuan Siao et al RESUSCITATION April 2015

Drive to start ECMO in SCGHED

Indications acute severe REVERSIBLE respiratory or cardiac

failure with a high risk of death that is refractory to conventional management

poor gas exchange compliance lt 05mLcmH2Okg PF ratio lt 100 shunt fraction gt 30

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 2: ECMO in Cardiac Arrest

references LITFL Alfred Hospital ECMO Project

What is it ECMO is extra-corporeal membrane oxygenation extracorporeal life support (ECLS) may be a better

term The extracorporeal circuit allows for the

oxygenation and removal of carbon dioxide from blood

used as a supportive strategy in patients who have a high risk of death despite conventional therapy

Why are we considering it in the ED for Cardiac Arrest ldquoPatients with refractory ventricular fibrillation

receiving E-CPR tended to have higher survival rates and significantly improved neurological outcomes when compared with those receiving C-CPRrdquo Managing cardiac arrest with refractory ventricular fibrillation in the emergency department Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation1113088 -Fu-Yuan Siao et al RESUSCITATION April 2015

Drive to start ECMO in SCGHED

Indications acute severe REVERSIBLE respiratory or cardiac

failure with a high risk of death that is refractory to conventional management

poor gas exchange compliance lt 05mLcmH2Okg PF ratio lt 100 shunt fraction gt 30

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 3: ECMO in Cardiac Arrest

What is it ECMO is extra-corporeal membrane oxygenation extracorporeal life support (ECLS) may be a better

term The extracorporeal circuit allows for the

oxygenation and removal of carbon dioxide from blood

used as a supportive strategy in patients who have a high risk of death despite conventional therapy

Why are we considering it in the ED for Cardiac Arrest ldquoPatients with refractory ventricular fibrillation

receiving E-CPR tended to have higher survival rates and significantly improved neurological outcomes when compared with those receiving C-CPRrdquo Managing cardiac arrest with refractory ventricular fibrillation in the emergency department Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation1113088 -Fu-Yuan Siao et al RESUSCITATION April 2015

Drive to start ECMO in SCGHED

Indications acute severe REVERSIBLE respiratory or cardiac

failure with a high risk of death that is refractory to conventional management

poor gas exchange compliance lt 05mLcmH2Okg PF ratio lt 100 shunt fraction gt 30

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 4: ECMO in Cardiac Arrest

Why are we considering it in the ED for Cardiac Arrest ldquoPatients with refractory ventricular fibrillation

receiving E-CPR tended to have higher survival rates and significantly improved neurological outcomes when compared with those receiving C-CPRrdquo Managing cardiac arrest with refractory ventricular fibrillation in the emergency department Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation1113088 -Fu-Yuan Siao et al RESUSCITATION April 2015

Drive to start ECMO in SCGHED

Indications acute severe REVERSIBLE respiratory or cardiac

failure with a high risk of death that is refractory to conventional management

poor gas exchange compliance lt 05mLcmH2Okg PF ratio lt 100 shunt fraction gt 30

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 5: ECMO in Cardiac Arrest

Indications acute severe REVERSIBLE respiratory or cardiac

failure with a high risk of death that is refractory to conventional management

poor gas exchange compliance lt 05mLcmH2Okg PF ratio lt 100 shunt fraction gt 30

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 6: ECMO in Cardiac Arrest

Absolute Contraindications progressive non-recoverable cardiac disease (not

transplant candidate) progressive and non-recoverable respiratory disease

(irrespective of transplant status) chronic severe pulmonary hypertension advanced malignancy GVHD gt120kg unwitnessed cardiac arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 7: ECMO in Cardiac Arrest

Relative Contraindications age gt 75 multi-trauma with multiple bleeding sites CPR gt 60 minutes multiple organ failure CNS injury

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 8: ECMO in Cardiac Arrest

Types VV = veno-venous VA = veno-arterial peripheral or central Veno-pulmonary artery ECMO (provides short-

term right ventricular and respiratory support following LVAD insertion)

high (2 venous cannulae) vs low flow (1 venous cannula)

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 9: ECMO in Cardiac Arrest

VV ECMO most common mode venous drainage from large central veins -gt

oxygenator -gt venous system near RA support for severe respiratory failure (no cardiac

dysfunction) Proven to be improve survival 6months (63

vrs 47) with acute respiratory failure

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 10: ECMO in Cardiac Arrest

VV ECMO

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 11: ECMO in Cardiac Arrest

Pathology pneumonia ARDS -acute GVHD pulmonary contusion smoke inhalation status asthmaticus airway obstruction aspiration bridge to lung transplant drowning

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 12: ECMO in Cardiac Arrest

VA ECMO venous drainage from large central veins -gt

oxygenator -gt arterial system in aorta support for cardiac failure (+- respiratory failure)

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 13: ECMO in Cardiac Arrest

Pathology graft failure post heart or heart lung transplant non-ischaemic cardiogenic shock failure to wean post CPB bridge to LVAD drug OD Sepsis PE cardiac or major vessel trauma massive pulmonary haemorrhage pulmonary trauma acute anaphylaxis

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 14: ECMO in Cardiac Arrest

The ALFRED guidelines Patients in the EampTC with out-of-hospital cardiac arrest which is

refractory to standard advanced cardiac life support (ACLS) treatment AND

The patient meets ALL the following criteria in regards to the characteristics of the arrest

Likely due to Respiratory or Cardiac cause Witnessed arrest Chest compressions started within 10 mins Less than 60 mins duration in total 12-70 years old No major co-morbidities

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 15: ECMO in Cardiac Arrest

The patient is profoundly hypothermic (lt32degC) due to accidental exposure

The patient has taken a significant overdose of a vaso-active drug(s) (ie β-Blocker tricyclic acid digoxin etc)

Any other cause where there is likely to be reversibility of the cardiac arrest if an artificial circulation can be provided

In order to ensure that out-of-hospital cardiac arrest patients arrive within a short time-frame eligible patients will be transported by ambulance with an AutopulseTM as soon as possible after the initiation of ACLS

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 16: ECMO in Cardiac Arrest

STEPs1 Identify potential patient2 US guided Line- Venous and Arterial (Training Required)3 Prime Circuit (Training Required)4 Attach Circuit5 Intensive Care6 Optimize and treat potential casues

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 17: ECMO in Cardiac Arrest

Cannulation Itrsquos central access whatrsquos the big deal

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 18: ECMO in Cardiac Arrest

The Circuit

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23
Page 19: ECMO in Cardiac Arrest

httpswwwyoutubecomwatchv=OM27HovykWY

  • ECMO in Cardiac Arrest
  • references
  • What is it
  • Why are we considering it in the ED for Cardiac Arrest
  • Indications
  • Absolute Contraindications
  • Relative Contraindications
  • Types
  • VV ECMO
  • VV ECMO (2)
  • Pathology
  • VA ECMO
  • Slide 13
  • Pathology (2)
  • The ALFRED guidelines
  • Slide 16
  • STEPs
  • Cannulation
  • Slide 19
  • Slide 20
  • Slide 21
  • The Circuit
  • Slide 23