Download pdf - MD/PhD Program “Molecular Medicine“ - MH-Hannover · Chairman of the MD/PhD program The MD/PhD program “Molecular Medicine“ was established in autumn 2000. Our program has

MD/PhD Program “Molecular Medicine“

Hannover Medical School

Report 2005

MD/PhD Program “Molecular Medicine“

Hannover Medical School (MHH)

Responsible Univ. Prof. Dr. Reinhold E. Schmidt Chairman MD/PhD Program Carl-Neuberg Str. 1 30625 Hannover Tel: 0511-532-6656 [email protected] MD/PhD committee:

Prof. Dr. A. Gossler, Prof. Dr. G. Brabant, Prof. Dr. C. Baum, Prof. Dr. C. Klein, Prof. Dr. R. Lichtinghagen, Prof. Dr. M. Gaestel, HD Dr. B. Sodeik, PD Dr. T. Tschernig, Dr. E. Jäckel, Dr. C. Nassenstein (final exam Nov. ‘05), Dr. E. Hesse/ Prof. Dr. D. Gadzicki, Dr. M. Ünalan, M. Rhein Dr. Susanne Kruse, Marlies Daniel MD/PhD Office

OE 9117 Carl-Neuberg Str. 1 30625 Hannover Tel. 0511-532-6011 [email protected] [email protected] Internet: www.mh-hannover.de/studium/phd

Chairman of the MD/PhD program

The MD/PhD program “Molecular Medicine“ was established in autumn 2000. Our program has meanwhile become one of the leading PhD programs in Germany due to excellent interdisciplinary cooperation between the Hannover Medical School (MHH), the University, the School of Veterinary Medicine Hannover and the Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, due to the support of the International Promotion Program (IPP) by DAAD and DFG. We are also proud to have international outstanding teachers, such as Prof. Fritz Melchers, in our program. It is also the first German PhD program which has been accreditated according to European standards (modules ECTS). There is a good ratio between medical students and students from life sciences as well as between German and foreign students. This program attracts great national and international interest. Additionally, the MD/PhD program is the basis for the Hannover Biomedical Research School (HBRS) founded in 2003, which is extremely successful in integrating all postgraduate programs at MHH. Joint curricula have been established. Currently, HBRS is applying for funds in the Excellence Initiative and has already passed the first round.

We meanwhile can be proud of three classes which have successfully graduated from the program. They are ambassadors for MHH around the world. Many sponsors are generously providing support for our workshop or even better stipends for our students. Many thanks to everyone who has supported this MD/PhD program, especially to those students who determine the excellence of the program.

Reinhold E. Schmidt, MD Professor of Medicine and Immunology

Dean of Hannover Biomedical Research School

We express our thanks to our sponsors: “Friends of MHH” Martin Lawrenz, Hannover

Table of Contents

I. Current Status, Problems and Prospects _________________________ 7

1. Current Status ____________________________________________________________________ 7 2. Common Rules ___________________________________________________________________ 10 3. Cooperation with International Institutes_____________________________________________ 11 4. Success and measures for implementation ____________________________________________ 12

II. Measures and Results _______________________________________ 13

1. Personnel _______________________________________________________________________ 13 1.1. Scientific collaborators and administrative personnel__________________________________________ 13 1.2. Tutors ______________________________________________________________________________ 14

2. Language courses_________________________________________________________________ 14 3. Social Activities __________________________________________________________________ 14 4. Organization of Educational Material________________________________________________ 15 5. Marketing Measures ______________________________________________________________ 15 6. Guest Lectures and additional colloquia ______________________________________________ 16 7. Travel __________________________________________________________________________ 17 8. Visits abroad by the graduate students _______________________________________________ 17

6

I. Current Status, Problems and Prospects

1. Current Status

Statistics Applications 2005

Country Number of applicants Now in the program

Total female male total female male

Germany 25 14 11 8 4 4

Western Europe: 12 5 7 - - -

Central and Eastern Europe

32 17 15 - - -

North America: 2 1 1 - - -

Latin America: 4 3 1 1 - 1

Africa, Subsahara: 28 10 18 1 1

North Africa and Middle East:

18 5 13

Asia, Australia and Oceania:

263 84 179 10 4 6

Total: 384 139 245 20 9 11

Final exams in the MD/PhD program 2005:

12 students did their final exams in November 2005. From 18 students of the year 2002, 9 did their

final exams after exactly 3 years = 50%, seven plan to finish after 3,5 years, two after 4 years.

Detailed Description At the moment (February 2006) there are 70 students in the program [30 women and 40 men; 51

international and 19 Germans; 19 medical students (incl. veterinary students) and 51 life scientists].

The international students come from Bolivia (1), China (5), Columbia (1), Estonia (1), Ethiopia (1),

Georgia (1), Hungary (1), India (30), Indonesia (1), Kenia (2), Mongolia (1), Poland (1), Slovakia (1),

Syria (1), the Netherlands (1), Ukraine (1) and Zimbabwe (1).

7

The students are either financed by the corresponding departments or by scholarships (DAAD;

industry etc.). We are very grateful that in 2005 the MHH provided for the second time ten half

stipends (about 1.000,-Euro/month for 18 months) for the best ten students of the ranking list after

selection.

Concerning selection of the new students, a 3-step level procedure was introduced in 2002. It consists

of: 1. preselection by the PhD commission, 2. a written test in the individual home countries, 3. an

interview (in 2005 in Hannover, New Delhi and Hyderabad, India). In 2002 an extensive application

form was developed, which as further improved in 2005. Now, there is a joint application form

together with the PhD program “Infection Biology”.

The selection of the applicants is based on qualification only. The accepted candidates are supposed to

choose a department and a research project themselves. This means that there can be bottle-necks

regarding the guarantee of the financing of the students. For this reason scholarships were applied for

with e.g. the Excellence Initiative of the German government.

Students work on a 3-year research project in one of the departments of the MHH or at cooperating

institutes (see list of students). In addition, there is an obligatory program of teaching consisting of

seminars and tutorials (see list of lecturers).

In October 2003, the Graduate School: “Hannover Biomedical Research School” (HBRS) was founded

at MHH (director: Prof. Dr. R.E. Schmidt, office: Dr. S. Kruse). Here, all graduate programns [PhD

(MD/PhD “Molecular Medicine” and PhD “Infection Biology”, Graduate Colleges (GRK 705,

European GRKs “Pseudomonas” and “Strategiesof human pathogens to establish acute and chronic

infection”), etc.] are coordinated.

In 2004, a joint Curriculum of the HBRS [MD/PhD program, PhD program “Infection Biology”

(speaker: Prof. Dr. Förster) and Miditrain (GBF, EST Marie Curie, speaker: Prof. Dr. Hauser)] was

established in order to bundle resources.

In the first year, basics and methods of biology and medicine are taught. There are special in-depth

seminars for medical students as well as life scientists. Furthermore, specific tutorial series for the

MD/PhD program respective PhD “Infection Biology”/Miditrain were organized.

During the second academic year, focus lies more on current research projects (applied aspects). Since

2003, four main foci have been established in the MD/PhD program: Immunology; Infection;

Oncology and Differentiation; Genetics and Cell Biology (Fig. 2).

Besides an extensive English curriculum, guest seminars, scientific colloquia, discussions with the

supervisors and technical practical courses took place.

8

Most important are the so-called “soft skills“ as well as seminars about “Research Ethics” (members of

the institute of “Science and Ethics”, Bonn), “Ethics“ (Prof. Schmidtke), “Animal Experiments“ (Prof.

Hedrich), “Scientific Writing“ (Dr. Kruse), “Presentation techniques” (Prof. Dierks), “Bioinformatics”

(Zheng, GBF), “Intercultural communication” (together with Göttingen and Ulm) etc.

The students keep book about all seminars. At the end of every semester an evaluation of the

educational programs and lecturers is performed.

After 18 months, students give an oral intermediate exam in the respective main subject and the

subject of the co-supervisor (presentation and discussion of a research paper). After 3 years the final

exam takes place in form of a public disputation.

In 2005, twelve MD/PhD students (Syed Raza Ali, India, Clinical Immunology; Srinivas Annavarapu

Rao, India, Endocrinology; Wahid Ansari, India, Clinical Imunology; Meta Djojosubroto, Indonesia,

Gastroenterology; Thomas Gebhardt, Germany, Gastroenterology; Claudia Karacsonyi, Argentina,

Cell Biology; Varsha Kumar, India, Clinical Immunology; Jianyun Liu, Visceral Surgery; Christina

Nassenstein, Germany, Fraunhofer Institute; Axel Schambach, Germany, Hematology and Oncology;

Amar Deep Sharma, India, Gastroenterology; Frank Traub, Germany, Pathology) sucessfully finished

the program, whereby 9 from altogether 18 of the year 2002 needed exactly 3 years. The remaining six

students will perform the final exams either on June 9th, 2006 (seven) or November 10th, 2006 (two).

The ECTS System was introduced (credit points = cp; see Fig. 1). The program was accreditated

according to European standards by ZEvA on December 9th, 2003.

Figure 1. Study Structure MD/PhD Program “Molecular Medicine“

9

3-year PhD project work (125 cp) Annual presentation in department (3x; 10 cp) Journal club (3x; 3 cp) Public annual presentation/project report (3x; 10 cp) Talk/presentation on international congress (2 cp)

Basics (seminar and tutorial; 3 h per week; 8 cp)

Year 1 Year 2 Year 3

Interdisciplinary seminars/courses (60 h; 6 cp) Project-orientated seminars/courses (80 h; 8 cp)

PHD thesis and

Final exam Complex and clinical

systems (seminar and tutorial; 3 h per week; 8 cp)

Intermediate Exam after 18 months

Figure 2. Curriculum 2005/6

In September 2002, a German-wide network of biomedically orientated PhD programs was established

(currently 15 members). Further improvement of the coordination of selection procedures (exams and

interviews) was achieved. In 2005, the second joint workshop on “Intercultural communication” took

place in Bergkirchen, organized by the PhD programs of Ulm, Göttingen and Hannover.

2. Common Rules

On 15.12.99, a rule for the MD/PhD program was passed by the senate of Hannover Medical School.

This rule unites a regulations for studies and exams. On 12.02.02, the MD/PhD program received

authorization from the Lower Saxony Ministry for Science and Culture to alternatively award besides

the PhD title for scientists the title Dr. rer. nat. Such changes in the rules and adaption to the program

situation were passed by the senate on 04.06.02. On 11.02.04, the rules were adapted to the

suggestions by the committee of referees for accreditation and were overall updated, same accounts for

April 2005. The PhD rules consider all aims of the program.

10

3. Cooperation with International Institutes

Fortunately, within the MHH there is an active exchange, i.e. participation of almost all scientifically

active departments in the MD/PhD program – whether by means of active organizing within the

MD/PhD commission, by supervising the MD/PhD students at the research laboratories or as lecturers

in the numerous educational programs. This goes for the basic scientific as well as for the clinically

orientated departments, for example: Biochemistry, Cardiology, Cell Biology, Clinical Immunology,

Dermatology, Gastroenterology-Hepatology-Endocrinology, Genetics, Hematology, Heart and

Thoracic Surgery, Immunology, Microbiology, Molecular Biology, Nephrology, Oncology, Pathology,

Physiology, Rheumatology, Tumor Biology, Virology, Visceral and Transplantation Surgery, etc.

Therefore intensive cooperation exists between collaborators (Post-docs etc.) from Graduate Colleges

with the MD/PhD program. Moreover, the “Graduate School” (HBRS) was founded in October 2003.

There is close cooperation between the graduate and PhD programs of the School of Veterinary

Medicine Hannover, also concerning lecturers and students. In addition, there are very close

cooperations to the GBF in Braunschweig and the Fraunhofer Institute (ITEM) in Hannover. Thanks to

the scientists of the MHH there is already intensive cooperation with European and internationally

very well-known research institutes (e.g. also by means of the European Graduate College

“Pseudomonas: Pathogenicity and Biotechnology“). Of course, the PhD students profit from this

cooperation, too.

A constant exchange and participation in education and research exists with the following institutes:

a) national:

• German Research Center for Biotechnology (GBF); Braunschweig • School of Veterinary Medicine, Hannover • Fraunhofer Institute for “Toxicology and Experimental Medicine” (ITEM), Hannover • Max Planck Institute for “Experimental Endocrinology“, Hannover • Institute for “Animal Breeding”, Mariensee (FAL) • Center for Stem Cell Research, Gatersleben

There is intensive cooperation with these national institutes as well as concerning education (lecturers)

and concerning research, i.e. making three year projects available or the function of scientists as co-

supervisors.

b) international (especially with):

• Centre for DNA Fingerprinting (CDFD), Hyderabad, India With Prof. Dr. S. Hasnain there has been intensive contact since 2002 (see guest lecturer and trip to India). The establishment of a mutual “summer school“ is planned and the exchange of scientists.

11

c.) Economy/Industry (especially with):

Solvay GmbH Hannover, Schering AG Berlin and Novartis GmbH Basel

Industry excursions (e.g. Solvay AG, Hannover; Bayer AG, Research Center, Wuppertal) are regularly

taking place.

4. Success and measures for implementation

In 2005, twelve students successfully finished the MD/PhD program (see above). Some of the finalists

continue to work at MHH or German universities (medical consultant, Postdoc etc.). Eight of them

already went to work as Postdocs abroad (UK, USA, Australia, China, Switzerland). The MD/PhD

program plans to establish an ALUMNI organization on the long-term range. At the moment the PhD

students form a sub-group of the MHH Alumni e.V.

The MHH has guaranteed to continue financial support of the MD/PhD program after discontinuation

of the support by the DAAD/DFG (after 5 years). The DAAD has extended their financial support for

2005 and 2006 after an extremely successful evaluation of the program. The MHH already provided

ten grants to excellent stdents per year (see above).

The MD/PhD program plays a key role (scientific, organization) in Hannover Biomedical Research

School (HBRS). The establishment of the Graduate School will be considered in the future budget

(personel and consumables). Currently, MHH is applying for funds for HBRS in course of the

Excellence Initiative.

Furthermore, the accreditation (see above) implements the program.

The program was very successful in gaining sponsors, either for the annual workshop, the year book or

for student’s grants (see list on page 6). A sponsoring concept as well as special flyers were developed.

12

II. Measures and Results The MD/PhD Program “Molecular Medicine“ started in winter semester 2000/01. Since 01.01.2002,

the program is supported by the DAAD/DFG by means of the “International Promotion Program”

(IPP).

1. Personnel

Within the IPP the posts for a scientific coordinator (full time) and funds for assistant students (see

“non scientific care”; 10 hours/week) have been granted.

1.1. Scientific collaborators and administrative personnel

Since 01.05.2002, Dr. Susanne Kruse has been working on the program as scientific coordinator. She

is a graduated biologist and, therefore, most competent for the sector “Molecular Medicine”. She has

various tasks; she is responsible for the total coordination and organization of the MD/PhD program

and HBRS, e.g.

• Consultation of the PhD students and applicants

• Organization and coordination of the application and selection procedure

• Cooperation with the PhD commission and HBRS

• Processing of the PhD commission meetings

• Contact to supervisors and lecturers of the Medical School and cooperating institutes

• Public relations (articles, homepage design etc.)

• Marketing (flyers, poster, advertisements etc.)

• Fund raising (incl. sponsors); applications (DFG, BMBF etc.)

• Planing and coordination of the curriculum (including “Soft skills”)

• Organization of workshops/seminars

• Presentation of the seminar “Scientific Writing“

• Evaluation of seminars and tutorials

• Preparation of exams and coordination

• Organization of the inauguration, non scientific care and social activities

• Contact to DAAD and other PhD programs (esp. MD/PhD Network)

• Administration of the budget

• Instruction of the person in charge (Mrs. Daniel), the German teacher (Mrs. Marotz)

and assistant students (see below!)

13

Mrs. Marlies Daniel works at the PhD Office (full time) as person in charge/correspondant. Her

position is financed by the Hannover Medical School.

Mrs. Daniel supports Dr. Kruse with the coordination und organization of the MD/PhD program. She

is responsible for the total correspondence, telephone calls, organization of the application procedure,

taking care of the students (esp. during the training period: organization of accommodation, banks,

insurance etc.), statistics etc.

1.2. Tutors

In 2005, Tracey Gillman, E. Makono Mayhar (Mike), Ruth Knorr und Florian Bittner have been

employed as assistant students on an hourly basis. These tutors especially take care of the MD/PhD

students in close cooperation with the “International Office” (concerning culture, geography, history

and institutions), help at German authorities, help at International evenings and with the homepage.

2. Language courses

Mrs. Petra Marotz has been employed as the German teacher since 01.10.2002 (hourly basis) with a

lectureship. She teaches the foreign PhD students in two courses à 2 hours/week. This concerns a

course for beginners and an advanced course (1 year experience). A total of over 20 PhD students of

HBRS participate in the courses.

3. Social Activities

• On 19.02.05, a joint “Bowling“ evening for students of all PhD programs was organized.

• On 30.04.05, a day excursion by bus to Bremen was taking place (Science Center) in close

cooperation with the International Office.

• Regular tables were held in the Maza, City Centre.

• On 07.07.05, summer term was closed with an international barbeque for all PhD students,

lecturers and supervisors in HBRS.

• On 08.07.05, an excursion to the Biotech company „BioVision AG“ Hannover was organized with

about 20 students from HBRS.

14

• Orientation weeks (04.10.-17.10.05) were financially supported by the “WIN“ program (Welcome

in Niedersachsen) of Lower Saxony.

• The opening of term / welcome of new students was celebrated on 17.10.05. All students,

supervisors and lecturers of the MD/PhD program “Molecular Medicine“ and PhD program

“Infection Biology” as well as the president of MHH and several guests (e.g. State secretary Dr.

Lange, MWK) participated. Invited spealer was Prof.’in Dr. U. Beisiegel (University Clinics

Hamburg Eppendorf, see also 6.), musical introduction by: A. Barkhoff + Band.

• On 11.11.05, the festive ceremony after the final exams took place. Invited guest speaker was Prof.

Dr. Braun (Max-Planck Institute, Bad Nauheim) (see also under 6.), musical introduction by Nora

Teschner (Cellotrio).

• On 25.11.05, students visited a variete in cooperation with the International Office.

• On 14.12.05, an international Christmas Party was celebrated with all students, supervisors and

lecturers of HBRS (all programs).

4. Organization of Educational Material

No particilar aquisitions were made in this sector.

5. Marketing Measures

• For marketing uses, flyer and poster were created and printed by the agency HzweiS. These were

distributed on meetings, congresses, within MHH and other universities.

• A large number of ads were published in Nature, Science, New Scientist, Laborjournal etc.. The

resonance was enourmous (400 applications).

• Within MHH, poster are put up to inform employees and students of events (info meetings,

ceremonies etc.), printed by the “Forschungswerkstätten”.

• A year book 2004 was printed.

• On 17.02.05, an info meeting on the MD/PhD program was organized for students/candidates.

• Because of the accreditation, the MD/PhD program serves as a model and advisor for lots of other

programs.

15

6. Guest Lectures and additional colloquia

• On 28.01.05, Dr. Kruse held the seminar “Scientific writing“ at MHH.

• From 10.-12.03.05, the annual Stephansstft Workshop (retreat) was taking place. Students had to

present and discuss their projects with all participants (students, supervisors, lecturers). In addition

assemblies of students as well as lecturers/supervisors were organized. The international evening

was planned for Friday. The workshop was financially supported by a number of sponsors.

• On 26.04.05 and 03./04.05.05, members of the Institute of “Science and Ethics“ in Bonn were

invited to hold the seminar “Research Ethics“ at MHH (participants 20 students and scientists from

HBRS)

• On 10.05.05, the written test for new applicants was given at MHH. In addition, tests were

organized in home countries of candidates.

• From 26.-27.05.05, GBF offered the workshop “Bioinformatics“ in Braunschweig.

• From 03.-05.06.05, the workshop “Intercultural Communication“ took place in Bergkirchen (near

Hannover) in a joint effort of PhD programs in Ulm, Göttingen and Hannover.

• From 14.-16.03.05 and from 21.-25.11.05, Prof. Hedrich and colleagues held the course “Animal

Experiments“ for HBRS students at MHH.

• Altogether 72 applicants were invited for interview in Hannover, New Delhi (India; DAAD office)

and Hyderabad (India; CDFD) June/ July 2005. Candidates had to give short presentations of

previousexperimental work and were asked questions (total 20 min).

• On 07.07.05, the seminar “Career perspectives“ was given by Dr. Kruse at MHH.

• From 18.-19.07.05, the workshop “Presentation techniques“ was offered by PD Dr. Dierks (MHH).

Aim was to prepare students for presentations on congresses, meetings etc.

• On 04.10.05, Prof. Rouse, Tennessee, USA was visiting MHH and gave a guest lecture.

• From 19.-20.09.05, the seminar „Gene Technology Security“ was organized by Dr. Mertsching

(Gene Security Officer). The course was given at MHH for the second time in English. Participants

receive a certificate, which enablees to work as project leader in the field of genetechnology and

working with pathogenic microorganisms.

• On 17.10.05, the opening of term took place with the guest speaker Prof.’in Dr. U. Beisiegel

(University Clinics Hamburg Eppendorf).

16

• On 24.10.05, Prof. Melchers gave lecture in couse of the HBRS curriculum.

• On 11.11.05, final exams (public defenses, in English) were organized for twelve MD/PhD

students. At least one external reviewer was invited (Maurer, Berlin; Manes, Madrid/Spanien;

Karlsson, Lund/Schweden; Bürger, Münster; Fischer, Berlin; Hengstler, Leipzig; Andersson,

Malmö/Schweden; Nieswandt, Würzburg; Zwirner, Göttingen; von Zglinicki, Newcastle/UK;

Kabelitz, Kiel; Geissler, Regensburg; Schlitt, Regensburg). On the evening of the festive

ceremony, Prof. Dr. T. Braun was invited as guest speaker. Musical introduction was given by

Nora Teschner. During their stay in Hannover, some of the external reviewers gave guest lectures

talking about their own research results.

7. Travel

• From 03.-05.02.05, Dr. Kruse participated in the EUA meeting “Doctoral programs for the

Knowledge Society“ in Salzburg

• On 17.05.05, Dr. Kruse was invited to give a lecture on the DAAD meeting “Qualitative Selection

of international students: Do we need tests?” in Hamburg.

• From 30.-31.05.05, Dr. Kruse and Prof. Dr. R. E. Schmidt participated in the annual IPP (DAAD)

meeting in Berlin.

• From 25.06.-01.07.05, Dr. Kruse and Prof. Dr. R. E. Schmidt performed interviews with 30 Indian

applicants in New Delhi (DAAD office) and at CDFD Hyderabad durch. From these, nine students

were selected for the MD/PhD program.

• From 21.-24.09.05, Dr. Kruse was invited by the “German Socuiety of Immunology“ to give a

seminar on “New international structured programs in Germany (Master/PhD)“ in course of the

annual congress in Kiel.

8. Visits abroad by the graduate students

• Altogether 72 applicants were invited for interviews in June/July 2005 (see above).

• For all new students travel costs to Hannover were supported by the “WIN” program (see above;

October 2005)

• Overall, the MD/PhD students attended numerous meetings, congresses and short research stays

abroad. They were supported by the departments, DAAD, DFG etc.

17

Year 2001

Christoph M. Happel

Vladimira Jakubcakova

Yijiang Li

College/University: Universtiy of Frankfurt/Main, Germany

Highest degree:MD

Major Subjects:Medicine, Cell Biology

Projects/Research:Evaluation of Metal-Complexes conjugated to Peptide Nucleic Acids as Nucleases

Hobbies and other interests:family, reading, running, architecture

Publications:Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24) Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C,Schlegelberger B. Annals of Human Genetics, 2005, accepted

Cu(II) Complexes of Nitrogen Ligand - Oligopeptide Conjugates as Potential Artificial Nucleases Kirin SI, Happel CM, Klein C, Metzler-Nolte N. In Epton, R. (Ed.), 'Innovation and Perspectives in Solid Phase Synthesis and CombinatorialLibraries‘ (Proceedings of the Eighth International Symposium, London, 2003), ISBN0-9515735-5-1, Mayflower Worldwide Ltd., Kingswinford, U.K., 2004 261-262

Synthesis, structure and comparison of the DNA cleavage ability of metal complexes M(II)L with the N-(2-ethoxyethanol)-bis(2-picolyl)amine ligand L (M Co, Ni, Cu and Zn) Kirin SI, Happel CM, Hrubanova S, Weyhermüller T, Klein C, Metzler-Nolte N. Dalton Trans., 2004 1201-1207

Quantitative analysis of epithelial cell aggregation in the diploblastic metazoan Hydra reveals a switch from homotypic to heterotypic cell interactions. HobmayerB, Snyder P, Alt D, Happel CM, Holstein TW. Cell Tissue Res, 2001 (304) 147-157

Wnt signaling molecules act in axis formation in the diploblastic metazoan hydra. Hobmayer B, Rentzsch F, Kuhn K, Happel CM, Cramer v Laue C, Snyder P, Rothbächer U, Holstein TW. Nature, 2000 (407) 186-189

Education

First names:Christoph M.

Last name:Happel

Date of birth:16.04.1974

Country:Germany

E-mail:[email protected]

Supervisor:Prof. C. Klein

EducationCollege/University:Faculty of Nature SciencesUniversity of P.J SafarikDepartment of Molecular Biology; Kosice, Slovakia

Highest degree:Dr. rer. nat. (RNDr.)

Major Subjects:Molecular biology, neurobiology, chronobiology

Projects/Research:Circadian RhythmsThe Role of PKCα in Circadian Rhythms

Scientific Interests and Goals:My aim is to improve myself in research, to be good scientist...

Hobbies and other interests:life, nature, travelling, music, ...

First name:Vladimira

Last name:Jakubcakova


Country:Slovakia


Supervisor:Prof.EicheleMax-Planck-Institute of Experimental Endocrinology

EducationCollege/University:1994-1999 Bachelor of Medicine Univ. in Xi‘An1999-2001 Master of Medicine Univ. in Xi‘An

Higest degreeM.B., M.Sc. in Medicine

Major subjectPulmonary Transplantation Immunology

Project /Research2003 - Suppression of MHC-Class II molecule up regulation by HMG-CoA reductase inhibitors in an allogeneic model of rat lung transplantation2002 - Tissue engineered carotids: immunological,histological and molecular characteristics

Scientific Interests and GoalsEvery aspect concerning the lungLung Transplantation & Transplant ImmunologyLung Preservation & Ischemia reperfusion injuryPulmonary Stem cell & Tissue EngineeringThoracic & Experiment Surgery

Hobbies and other interestsI have many hobbies, please visit my personal website, or leave message on my BBS.

Publication:Li, Y. Clinical Medicine of China 2001; 13 (9) :1297-1299

First Name:Yijiang

Last name:Li


Country:China

E-mail:[email protected]:www.ki.mycm.net

Supervisor:Prof. Axel Haverich

Year 2002

Diya Abraham

Georg Bohn

Shashi Kant

Gesa Meyer

Anika Meyerholz

Aravind Sekhar

Krishna Kumar Singh

Manvendra Singh

Linding Wang

EducationCollege/University:1999 B.Sc.-University of Mysore, India2001 M.Sc.-University of Mysore, India

Highest degree:M.Sc. in Biochemistry

Major Subjects:Microbiology, Zoology, Botany

Projects/Research:Functional analysis of the role of Protein kinase C gamma in the mammalian circadian clockRestoration of circadian rhythmicity in Per2/Cry1 mutants in constant light

Scholarships:1. Gold medallist in Master of Science2. Venkataraman Aarthie award

Scientific Interests and Goals:My main field of interest is Genetics and Molecular Biology.With the expertise I gain from these fields I would like tocontribute to the upliftement of mankind and society and alsounderstand to certain extent the great complexity of life.

Hobbies and other interests:Singing, Dancing, Cooking, Interior decoration, Reading,Flower arrangement

First name:Diya

Last name:Abraham


Country:India


Supervisor:Dr. M. LeitgesMax-Planck-Institutefor ExperimentalEndocrinology

EducationCollege/University:1994-1997 Albert Ludwigs Universität Freiburg1997-1998 Universidad de Salamanca, Spain1998-2002 Technische Universität München

Highest degree:MD (Dr. med.)

Major Subjects:Medicine

Projects/Research:Identification and characterization of three novel auxiliary γsubunits of voltage gated calcium channelsGeneration and characterization of hematopoietic stem cell lines as novel tools to investigate genetic and developmental aspects of congenital bone marrow failure syndromes

Scientific Interests and Goals:Identification and characterization of yet undefined congenital bone marrow failure syndromes and the genuine role of hematopoietic stem cells in the development and differentiation of the hematopoietic system

Hobbies and other interests:Music, opera and exhibitions, cooking

Publications:Klugbauer N, Dai S, Specht V, Lacinova L, Marais E, Bohn G, Hofmann F. FEBS Lett 2000; 470: 189-197Bohn G, Moosmang S, Conrad H, Stieber J, Ludwig A, Biel M, Klugbauer N, Hofmann F. JPN J Electrcardiol 2000; 20: 76-78Bohn G, Moosmang S, Conrad H, Ludwig A, Hofmann F, Klugbauer N. FEBSLett 2000; 481: 73-76Moosmang S, Bohn G, Conrad H, Ludwig A, Biel M, Klugbauer N, Hofmann F (2001) “Molecules contributing to cardiac pacemaker current” in Morad M, Kostyuk P Calcium Signaling (IOS Press): 262-264

First name:Georg

Last name:Bohn


Country:Germany


Supervisor:Prof. KleinPediatric Hematologyand Oncology

EducationCollege/University:2000-2002 School of Biotechnology, Madurai Kamarej University, Madurai, India

Highest degree:M.Sc. in Biotechnology

Major Subjects:Biotechnology

Projects/Research:Mechanisms of activation and substrate targeting in the MAP kinase cascadesCotransformation of multiple T-DNAs: Segregation analysis in the T1generationHydrophobic conserved residues of homeodomains

Scholarships:Have received DBT (Department of Biotechnology) studentship for 2years during my M.Sc.Have received educational stipend during my B.Sc. under rural experience program.

Scientific Interests and Goals:I am interested in the study of molecular mechanisms of activation of MAP kinase cascade and it´s target proteins.

Publications:Kant S, Bagaria A, Ramakumar S.Biochem Biophys Res Commun. 2002; 299(2):229-32.Schumacher S, Laa K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M. The EMBO Journal (2004) 23, 4770–4779

First name:Shashi

Last name:Kant


Country:India

E-mail:[email protected]@mh-hannover.de

Supervisor:Prof. Dr. M. GaestelPhysiological Biochemistry

EducationCollege/University:1995-2003 School of Veterinary Medicine Hannover, Germany

Highest degree:Dr. med. vet

Major Subjects:Toxicology, Cell Biology

Projects/Research:Molecular mechanisms of the inflammatory response of mastcells and colonocytes induced by Clostridium difficile toxins A and B: analysis of toxin-induced pro-inflammatory signalcascades.

Scientific Interests and Goals:To get further insights into the pathogenesis of intestinalinflammation induced by bacterial toxins using molecular and immunological techniques

Hobbies and other interests:Everything related to music: playing the violin, dancing…

First name:Gesa

Last name:Meyer


Country:Germany


Supervisor:Prof. Dr. JustInstitute of ToxicologyHannover Medical School

College/University:1995-2002: Hannover Medical School, human medicine

Highest degree:Dr. med.

Major SubjectsCell biology, Pediatrics, Internal Medicine

Projects/Research:Role of CALM in clathrin coat formation

Scientific Interests and Goals:Clathrin mediated endocytosis

Hobbies and other interests:playing the piano, literature

Publications:

meda A, Meyerholz A, Ungewickell E: Identification of the universal cofactor(auxilin 2) in clathrin coat dissociation. Eur J Cell Biol. 2000 May;79(5):336-42.

Meyerholz A, Hinrichsen L, Groos S, Esk PE, Brandes G, Ungewickell E: Effect of CALM Depletion on Clathrin Coat Formation. Traffic 2005, 6: 1225-1234

Education

First name:Anika

Last name:Meyerholz


Country:Germany

E-mail:meyerholz.anika@ mh-hannover.de

Supervisor:Prof. Dr. E. Ungewickell

EducationCollege/University:1996-2002 Bangalore Medical College, Bangalore

Highest degree:M.B.B.S.(Bachelor of Medicine & Surgery)

Major Subjects:Medicine, Surgery, Obstetrics & Gynaecology

Projects/Research:Genes specifically expressed in intestine epithelium

Scholarships:JNCASR Summer Research Fellowship `98

Scientific Interests and Goals:Developmental biology

Hobbies and other interests:Travel, Reading, Rock Music, Calligraphy

First name:Aravind

Last name:

Sekhar


Country:India


Supervisor:Prof. GosslerMolecular Biology

EducationCollege/University:1995-1998 Udai Pratap College/Purvanchal University1998-1999 Benaras Hindu University1999-2001 Goa University

Highest degree:M.Sc. (Biotech)


Projects/Research:Genetics of Marfan syndrome.

Scholarships:Grant from Proteina (2003-2004).

Scientific Interests and Goals:I want to pursue research in the field which has some direct effect in the medical sciences

Hobbies and other interests:Music, Cricket, Chess and literature.

Publications:Singh KK, Ristau S, Dawson WW, Krawczak M, Schmidtke J. Mapping of a macular drusen susceptibility locus in rhesus macaques to the homologue of human chromosome 6q14-15. Exp Eye Res. 2005 Oct;81(4):401-6.Singh KK, Schmidtke J. Single nucleotide polymorphisms within the promoter region of the rhesus monkey tumor necrosis factor-alpha gene. Immunogenetics. 2005 May;57(3-4):289-92.Rommel K, Karck M, Haverich A, von Kodolitsch Y, Rybczynski M, Muller G, Singh KK, Schmidtke J, Arslan-Kirchner M. Identification of 29 novel and nine recurrent fibrillin-1 (FBN1) mutations and genotype-phenotype correlations in 76 patients with Marfan syndrome. Hum Mutat. 2005 Dec;26(6):529-39Singh KK, Shukla PC, Rommel K, Schmidtke J, Arslan-Kirchner M. Sequencevariations in the 5' upstream regions of the FBN1 gene associated with Marfansyndrome. Eur J Hum Genet (in press)

First name:Krishna K.

Last name:Singh


Country:India


Supervisor:Prof. Dr. Jörg Schmidtke

EducationCollege/University:2000-2002 Madurai kamaraj University M.Sc in Biotechnology.



Projects/Research:1. Construction of antisense vector to studythe process of Melanin biosynthesis and UV induced inflammation.2. Production, purification, characterization and comparativestudy of a protease from a thermophilic fungi Thermomyceselanuginosus.

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology program. (2000-2002).2. Junior Research Fellowship (JRF) awarded by Council for Scientific and Industrial Research (CSIR), India.3. R&D Assistantship from JNCASR, Bangalore, India.

Scientific Interests and Goals:My main field of interest is Developmental Biology, I want to study the biology of Heart, Somite and Limb Patterning. I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us tounderstand this fascinating area of biology better.

Hobbies and other interests:Music, Cricket, Movies, literature, etc.

Publications:(1) Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A. The T-box transcription factor Tbx15 is required for skeletal development. Mechanisms of Development. 2005;122(2):131-44.(2) Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A. Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707.(3) Airik R, Bussen M, Singh MK, Petry M, Kispert A. Tbx18 regulates thedevelopment of the ureteral mesenchyme. Journal of Clinical Investigation(in press).

First name:Manvendra

Last name:Singh


Country:India


Supervisor:Prof. KispertMolecular Biology

EducationCollege/University:Anhui UniversityShanghai Institute of Biological Products

Highest degree:M.Sc. in Pathogenic Microbiology & Molecular Biology

Major Subjects:Cloning and expression of HIV-1 gag p24, env gp41 recombinantantigens and p24-gp41 fusion recombinant antigen in Escherichiacoli

Projects/Research:Functional characterization of M-type K15 of Kaposi’s Sarcoma-associated herpesvirus

Scholarships:DAAD

Scientific Interests and Goals:Molecular biology and virology; grasp the highest standardtechniques and serve people

First name:Linding

Last name:Wang


Country:China


Supervisor:Prof. SchulzVirology

Year 2003

Khaled Alkasah

Tammy Chang

Anuhar Chaturvedi

Dorothea Dijkstra

Dorothea Gadzicki

Jaba Gamrekelashvili

Arnab Ghosh

Shipra Gupta

Eric Hesse

Kumaravelu Jagavelu

Gustavo Salguero Lopez

Harini Nivarthi

Andri Pramono

Rahul Purwar

Bishnudeo Roy

Tibor Veres

Anastassiia Vertii

EducationCollege/University:1992-1996 BSc in Medical Laboratories, Sanaá University, Yemen.

Highest degree:MSc in Medical Microbiology, Sanaá University, Yemen.

Major Subjects:Microbiology, Haematology and Biochemstry.

Projects/Research:Viral and Genetic Detreminants of KSHV/HHV-8 Transmission from Mother to Child and its replication.

Scholarships:DAAD

Hobbies and other interests:Swimming and other sports

Publications:Dedicoat M, Newton R, Alkharsah KR , et al. Mother-to-Child Transmission of Human Herpesvirus 8 in South Africa. J Infect Dis. 2004;190(6):1068-75. Henke-Gendo C, Mengel M, Hoeper MM, Alkharsah KR, Schulz TF. Absence of Kaposi's Sarcoma–associated Herpesvirus in Patients withPulmonary Arterial Hypertension. Am J Respir Crit Care Med.2005;172(12):1581-5 Alkharsah KR, Dedicoat M, Deluca DS, Schulz TF, BlasczykR. Identification of two new HLA-A variants, HLA-A*2911 and HLA-A*6827. Tissue Antigens. 2006;67(2):170-2. Alkharsah KR, Dedicoat M, Blasczyk R, Newton R, Schulz TF. Association of HLA polymorphism with increased KSHV shedding in saliva. Manuscript in preparation.

First name:Khaled

Last name:Alkharsah


Country:Syria


Supervisor:Prof. Dr. T. F. Schulz Virology department

First name:Tammy

Last name:Chang


Country:Taiwan (R.O.C.)

E-mail:Tammy_CYS@ web.de

Supervisor:Prof. TümmlerKlinische Forschergruppe“Molecular Pathology of Cystic Fibrosis”

EducationCollege / University:1995-1997 Phillipps University Marburg, Germany1997-2003 Justus-Liebig University Gießen, Germany

Highest degree:Dipl. oec. troph.

Major Subjects:Biochemistry of Nutrition, Nutrition in developing countries

Project / Research:Pseudomonas aeruginosa – mammalian host cell interaction: Phagocyte-sensitizing genes of P. aeruginosa and Pseudomonas adhesion to human tracheobronchial mucin

Other Scientific Activities:Member of European Graduate Colleg: Pseudomonas -Pathogenicity and Biotechnology

Scientific Interests and Goal:Investigation & characterization of novel fitness factors whichenable survival of P. aeruginosa in granulocytesExamination of novel Pseudomonas adhesion mechanism

Hobbies and other interests:Sports (swimming, jogging), classical music, reading, cinema, enjoy a cup of freshly brewed coffee with a good friend

Publications:Iozef R, Rahlfs S, Chang T, Schirmer H, Becker K. FEBS Letters 2003 Oct;554:284-288

EducationCollege/University:1997-2001 B. Pharm, Department of Pharmaceutical Sciences

and Drug Research, Punjabi University Patiala, Punjab India.

2001 - 2002 MS (Pharm) Biotechnology, National Institute of Pharmaceutical Education and Research , Mohali, Punjab. India

Highest degree:MS(Pharm)

Major Subjects:Pharmacology, Pharmaceutics, Biotechnology

Projects/Research:Functional genomics using RNA-interference in hematopoieticcells

Scientific Interests and Goals:Functional analysis of individual signaling molecules by meansof RNAi in primary normal and malignant hematopoietic cellsthus to find targets for therapeutic interventation.

Scholarships1. Awarded by National Institute of Pharmaceutical

Education and Research for MS(Pharm) in Biotechnology-July 2001 to Dec 2002

2. Junior Research Fellowship awarded by Council of Scientific and Industrial Research India (Dec, 2002 )

Hobbies and other interests:Movies, Travelling and cooking

Publications:Agarwal S, Chaturvedi A., Roy N. Current Research and Information inPharmaceutical Sciences Vol. 3 No. 3 July - September 2002

First name:Anuhar

Last name:Chaturvedi


Country:India


Supervisor:Prof. Matthias EderHematology and Oncology

First Name:Dorothea (Dorrit)

Last Name:Dijkstra

Date of Birth:28.10.1977

Country:The Netherlands


Supervisors:Prof. Dr. T. WerfelDr. R. GutzmerDermatology

EducationCollege/University:1995-1999 Hogeschool IJsselland, Deventer, The

Netherlands1999-2001 Vrije Universiteit, Amsterdam, The

Netherlands

Highest degree:MSc (Drs.)

Major Subjects:Immunology, Dermatology, Pharmacology

Scientific Interests and Goals:To find out the role of anaphylatoxins C3a and C5a and their respective receptors in modulating the interaction between dendritic cells and T-lymphocytes in the skin. We will compare healthy subjects and patients with chronic inflammatory skin diseases as a model.

Hobbies and other interests:Parasitology (fascinating how they escape from host immune responses!), World Wildlife Foundation, Windsurfing, Skating, Friends, Drawing, Reading, Music, my parents dog Rocaille etc.

EducationCollege/University:1994-2001 Medizinische Hochschule Hannover, Germany

Highest degree:MD (Dr. med.)

Major Subjects:Genetics, Tumorigenesis

Projects/Research:Identification of secondary genetic changes in BRCA1/2-induced hereditary breast cancer development

Scholarship/Award:Junior Professorship for Hereditary Breast Cancer awarded bythe Lower Saxony Ministry of Science and Culture, Dorothea Erxleben Program (from November 2005)

Scientific Interests and Goals:To gain insight into fundamental molecular processes duringbreast cancer development, in particular of hereditary breastcancer, to improve the diagnostic procedures and adapttherapeutic strategies for a better prognostic outcome.

Hobbies and other interests:Literature, theatre, sports, drawing

Publications:Gadzicki D, Müller-Vahl K, Stuhrmann M (1999) A frequent polymorphism in the coding exon of the human cannabinoid receptor (CNR1) gene. Molecular and Cellular Probes 13:321-323

Gadzicki D, Müller-Vahl KR, Heller D, Ossegge S, Nöthen MM, Hebebrand J, Stuhrmann M (2004) Tourette Syndrome is not caused bymutations in the central cannabinoid receptor (CNR1) gene. Am J MedGenet B Neuropsychiatr Genet 127:97-103

Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, Wilkens L, Schlegelberger B. (2005) BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib. Cancer Genet Cytogenet 159:164-7

Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C, Schlegelberger B. (2006) Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24). Ann Hum Genet (in press)

First name:Dorothea

Last name:Gadzicki


Country:Germany


Supervisor:Prof. Dr. med. Brigitte Schlegelberger,Institute of Cell and MolecularPathology

EducationCollege/University:1996-2002 Tbilisi State Medical University, Tbilisi Georgia

Highest degree:MD

Major Subjects:Basic and tumor Immunology

Projects/Research:Influence of tumor cell death on tumor-specific immune responses

Scientific Interests and Goals:Mechanisms of immune tolerance & activation in tumor immunity

Hobbies and other interests:Table tennis, football, neuroscience.

Publications:Garbe AI. Vermeer B. Gamrekelashvili J. von Wasielewski R. Greten FR. Westendorf AM. Buer J. Schmid RM. Manns MP. Korangy F. Greten TF. Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses. Cancer Res. 2006 Jan 1;66(1):508-16.

Nizharadze N. Gongadze M. Sanikidze T. Gamrekelashvili J. Sumbadze C.Kevlishvili O. Effects of LPS on the proliferating processes in splenocytes. Proc. Georgian Acad. Sci., Biol., Ser. A., 2002, vol. 28, #5-6 pp. 573-576.

First name:Jaba

Last name:Gamrekelashvili


Country:Georgia


Supervisor:PD.Dr. T. GretenDepartment of Gastroenterology,Hepatology & EndocrinologyMH Hannover

EducationCollege/University:1996-2001 Mysore Medical College, India

Highest degree:MBBS


Projects/Research:Mechanisms and modulation of anti-leukemia immunity

Scientific Interests and Goals:To obtain further insights into management of childhoodleukemia

Hobbies and other interests:Exploring Indian wildlife; Anthropology and development of languages

First name:Arnab

Last name:Ghosh


Country:India


Supervisor:PD Dr. M. SauerPediatric Hematology and Oncology

EducationCollege/University:1998-2003: All India Institute of Medical Sciences (AIIMS),

New Delhi, India

Highest degree:M.Biotech.

Major Subjects:Biotechnology, Molecular Biology, Immunology

Projects/Research:Interaction of human hemofiltrate CC chemokine 1 derivatives

with various chemokine receptors: Implications for drug development.

Scientific Interests and Goals:To know more about the role of chemokines in allergic airway

diseases

Hobbies and other interests:Painting

PublicationsGupta S, Schulz-Maronde S, Kutzleb C, Richter R, Forssmann WG, Kapp A,

Forssmann U, and Elsner J; “Cloning, Expression and Functional Characterization of Cynomolgus Monkey (Macaca fascicularis) CC Chemokine Receptor 1”; Journal of Leukocyte Biology, 2005, Nov;78(5):1175-84

Elsner J, Dulkys Y, Gupta S, Escher SE, Forssmann WG , Kapp A, ForssmanU; “Differential pattern of CCR1 internalization in human eosinophils: prolonged internalization by CCL5 in contrast to CCL3”; Allergy, 2005, Nov;60(11):1386-93

Gupta S, Schulz-Maronde S, Forssmann U, Kutzleb C, Kapp A, ForssmannWG, and Elsner J; “Macaca fascicularis CC chemokine receptor 1(CCR1) gene” ; GenBank accession number DQ008589, 2005,15 Nov.2005.

First name:Shipra

Last name:Gupta


Country:India


Supervisor:Prof. Dr. W.G. ForssmannDept. of Pharmacology and Toxicology, MHH, HannoverProf. Dr. J. ElsnerDept. of Dermatology & Allergology

EducationCollege/University:since 2005 Yale University School of Medicine, USA1996-2005 Hannover University Medical School, Germany

Harvard University Medical School, USAUniversity of Birmingham, GBUniversity of Otago, New ZealandUniversity of Zurich, SwitzerlandUniversity of Cape Town, South Africa

Highest degree:M.D. (Dr. med.)

Major Subjects:Cell- and Molecular Biology

Projects/Research:Regulation of osteoblastogenesis and bone formation

Scientific Interests and Goals:Bone Biology

Scholarship:1. DFG Research Fellowship2. I-lab Award, Aventis Foundation3. Hannelore Munke Research Award, MHH4. DAAD Fellowship5. Scholarship, Bayer Leverkusen Foundation

Hobbies and other interests:Sports, Literature

Publications:Hesse E, Jagodzinski M, Wehmeier M, Horne WC, Baron R. Mechanoinduction of FosB in human bone marrow stromal cells. JBMR; Vol. 20, Suppl. 1, pp S356, September 2005.

Hesse E, Musholt PB, Potter E, Petrich T, Wehmeier M, von Wasielewski R, Lichtinghagen R, Musholt TJ. Oncofoetal fibronectin - a tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma. Br J Cancer. 2005 Sep 5;93(5):565-70

First name:Eric

Last name:Hesse


Country:Germany


Supervisor:Prof. R. Baron(Orthopaedics andCell Biology,Yale University)

EducationCollege/University:1997-1999 Bharathidasan University, Trichy, India

Highest degree:M.Sc.

Major Subjects:Microbiology

Projects/Research:Involvement of the p38-MK2 signaling pathway in artherogenesis

Scientific Interests:Developmental Biology

Hobbies and other interests:Photography, Lepidoptery, Travelling

Publications:Kumaravelu J, Shanmugasundaram GK, Unwala H, Ramamoorthi N, Banerjea AC. Genes and Immunity 2001; 2, 404-407.Ramamoorthi N, Kumaravelu J, Shanmugasundaram GK, Rani K, Banerjea AC. Genes and Immunity 2001; 2, 408-410.

First name:Kumaravelu

Last name:Jagavelu


Country:India

E-mail:[email protected]@hotmail.com

Supervisor:PD Dr. SchiefferCardiology

EducationCollege/University:1995-2001 Universidad Nacional de Colombia, Bogota Colombia

Highest degree:MD

Major Subjects:Cellular and molecular biology of cardiovascular diseases: Cellular and molecular mechanisms of angiogenesis.Role of progenitor cells in neovascularization

Projects/Research:Impact of biomechanical stretch in progenitor cell differentiation. Role of progenitor cells in Hypertension

Scientific Interests and Goals:My main goal is to apply the knowledge from research in molecular biology on the understanding of cardiovascular diseases. As a first approach I am working on in vitro and in vivomodels of vascular hypertension at a cellular and molecular level. It will open me new perspectives about potential applications of molecular technology and their impact on diagnostic and prevention strategies and more specific and effective treatments for these kind of diseases.

Hobbies and other interests:Take a walk by the mountains. Good music and literature.

First name:Gustavo

Last name:Salguero


Country:Colombia


Supervisor:PD. Bernhard SchiefferCardiology and Angiology

EducationCollege/University:B.Sc. Biochemistry, Daulat Ram College, Delhi Univrsity.M.Sc. Biotechnology, Madurai Kamaraj University

Highest degree:Master

Major Subjects:Biotechnology, Biochemistry

Projects/Research:Molecular analysis of transcription factors involved in dendritic cell developmernt

Hobbies and other interests:Reading, Indian classical dance.

First name:Harini

Last name:Nivarthi


Country:India


Supervisor:Prof. Dr. KleinPediatric Hematology and Oncology

EducationCollege/University:1999 B.Sc. University of Indonesia, Indonesia2003 M.Sc. University of Indonesia, Indonesia

Highest degree:M.Sc. in Microbiology Medicine

Major Subjects:Cell Biology, Embryonic Stem Cell

Projects/Research:Analysis of Thrombopoetin function on hematopoeticdifferentiation in mouse embryonic stem cell

Scientific Interests and Goals:My interest unravelling molecular mechanism of hematopoiesis in embryonic stem cell.

Hobbies and other interests:Playing piano, watching movie.

Publications:

Rekiansyah M, Pramesyanti A, Bella B, Kosasih H, Ma‘roef CN, Tobing SY, Rudiman PI, Alisjahbana B, Endi TP, Green S, Kalayanarooj S, Rothman AL, Sudiro TM. Southeast Asian J. Trop. Med. Public Health. 2005 ;36(5) :1187-1197.

Wang Z, Skokowa J, Pramono A, Ballmaier M, Welte K.Ann NY Acad Sci. 2005; 1044:29-40.

First name:Andri

Last name:Pramono


Country:Indonesia


Supervisor:Prof. Karl Welte

EducationCollege/University:Lucknow UniversityAll India Institute of Medical Sciences, New Delhi, India

Highest degree:M.Sc( Biochemistry)

Major Subjects:Biochemistry, Immunology

Projects/Research:T cell - keratinocyte interaction in chronic inflammatory skin

diseases

Scientific Interests and Goals:Doing good research in the field of Immunogy

Hobbies and other interests:Reading, Cricket

Publications:Purwar R, Werfel T & Wittmann M; IL-13 stimulated human keratinocytes

preferentially attract CD4+CCR4+ T-cells:Possible role in AtopicDermatitis. J Invest. Dermatol. 2006, (in press).

Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. Human keratinocytes respond to IL-18. Implication for the course of chronic inflammatory skin diseases. J Invest Dermatol 2005, 124 (6) 1225-33.

First name:Rahul

Last name:Purwar


Country:India


Supervisor:Prof.Dr. M. WittmannProf. Dr. T.WerfelDept. Of Dermatology & Allergology

EducationCollege/University:2001-2003 School of Biotechnology, Madurai Kamaraj University, Madurai, India

Highest degree:MSc in Biotechnology


Projects/Research:Contribution of B1 cells to the gut associated humoral immunity.

Scholarships •Received DBT (Department of Biotechnology, India) studentship during my MSc.• Junior research fellowship (JRF) awarded by Counsil for Scientific and Industrial Research (CSIR), India

Scientific Interests and Goals:I Have a particular interest in understanding the complexity of the regulation of immune responses.

First name:Bishnudeo

Last name:Roy


Country:India


Supervisor:Dr. S. WeissMolecular ImmunologyGBF

EducationCollege/University:1996-2003 Semmelweis University Budapest, Hungary

Highest degree:MD

Major Subjects:Respiratory Immunology

Projects/Research:Interaction between pulmonary dendritic cells and nerves duringallergic airway inflammation

Scientific Interests and Goals:Understanding the mechanisms of cross-talk between thenervous and immune system and investigating the contributionof neuroimmune interactions to allergy

Hobbies and other interests:Music, literature, languages, hiking

Publications:Vannay A, Fekete A, Muller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabo AJ. Kidney Blood Press Res. 2004;27(2):105-13.

Sander LE, Lorentz A, Sellge G, Coeffier M, Neipp M, Veres T, Frieling T, Meier PN, Manns MP, Bischoff SC. Gut. 2005 Nov 18

First name:Tibor

Last name:Veres

Date of birth:11. 06. 1978

Country:Hungary


Supervisor:Dr. BraunFraunhofer-Institute forToxicology and Experi-mental Medicine

EducationCollege/University:1993-1998 Kharkov State University -Kharkov, Ukraine2001-2003 Kadir Has University-Istanbul, Turkey

Highest degree:MSc in Biology

Major Subjects:Molecular Biology, Protein Interaction, Heat Shock Proteins

Projects/Research:Search for biological functions of Hsp25 phosphorylation

Scientific Interests and Goals:Hsps have essential cellular functions. This is the pillow thatprovides us with „soft landing“ once we fall unexpectedly. So I will try to learn how it works in details.

Hobbies and other interests:Alpine skiing (Bad Grund Club), Diving (PADI), Thai-Chi; Lab mice (at home) and Street cats (“Sokak Melek”, “SED”)

Publications:Memon A., Aktoprakligil D., Ozdemir A., Vertii A. Turk J. Bot 2001; 25:11-121

Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Dak E, Cagatay P, Gunay D, Buyukdevrim AS. Arch Pathol Lab Med. 2004 Aug;128(8):869-74.

Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Cagatay P, Gunay D, Sevim Buyukdevrim A. Ann Hum Biol. 2005 Sep-Oct;32(5):620-9.

First name:Anastassiia

Last name:Vertii


Country:Ukraine


Supervisor:Prof. Dr. M. GaestelDr. A. KotlyarovInstitut für Biochemie/Physiologische Chemie

Year 2004

Rannar Airik

Abdul Mannan Baru

Adan Jirmo Chari

Sangeeta Chauhan

Mingmin Chen

Prajeeth C.K.

Gamze Kabalak

Khurshed Iqbal

Joanna Jagielska

Nonsikelelo Mpofu

Frederick Onono

Erkembulgan Purevdorj

Aeheli Choudhury Roy

Jessica Schwermann

Meera Shah

Anurag Singh

Kirsten Sommer

Leena Srivastava

Basant Thakur

Murat Ünalan

Fei Zhao

EducationCollege/University:1998-2004 University of Tartu, Estonia

Highest degree:M.Sc. In Developmental Biology

Major Subjects:Developmental Biology, Molecular Biology

Projects/Research:Analysis of the function of the T-box gene Tbx18 in the murine kidney development.

Scientific Interests and Goals:To get further insights into the mechanism of tissue and organ patterning in early mammalian development.

Hobbies and other interests:Literature

PublicationsAirik R, Bussen M, Singh MK, Petry M, Kispert A. Tbx18 regulates the development of the ureteral mesenchyme. J. Clin. Invest. In press

First name:Rannar

Last name:Airik


Country:Estonia



First Name:Abdul Mannan

Last Name:Baru


Country:India


Supervisor:Dr. Georg Behrens.Clinical Immunology.

EducationCollege/University:1996-1999 Bachelors in Microbiology, Mumbai University, India1999-2001 Masters in Microbiology, Mumbai University, India

Highest Degree:Masters in Microbiology

Major subjects:Genetics, Biochemistry, Biotechnology, Medical and Industrial Microbiology

Project / Research:Roads to Presentation: Targeting the pathways in antigen uptake to dissectout mechanisms for cross presentation.

Credentials and scholarships:• Topped Mumbai University in Microbiology at Bachelors level.• Worked as a Junior Research Fellow at TIFR, Mumbai, under Indo-Frenchcollaborative grant.• Worked as a Senior Research Fellow at TIFR, Mumbai under ICMR grant.

Scientific Interest and goals:To understand and characterize the cells and processes involved in immune protection.

Hobbies and other interests:Stage, Reading, Music.

EducationCollege/University:1994-1998 B.Sc (honours) Moi Univ.-Kenya2000-2003 M.Sc (Immunoparasitology) University of

Nairobi-Kenya

Highest degree:M.Sc (Immunoparasitology)

Major Subjects:Immunology,Virology and Parasitology

Projects/Research:Assessment and Modulation of CD8+T cell responses to HSV-1 Epitopes for induction of effective CTL-immunity :The Role of DC in antiviral immune responses Vs Viral Factors Required for Entry,Immune Evasion and Latency development for HSV-1 in Transgenic Mouse Models

Scientific Interests and Goals:Elucidation of scientific principles and their translation intobeneficial-societal use

Hobbies and other interests:Soccer,Chess and Charting with friends

First name:Adan

Last name:Chari Jirmo


Country:Kenya

E-mail:[email protected]@mh-hannover.de

Supervisor:Prof. BehrensClinical Immunology

EducationCollege/University:2001-2003 University of Jammu, M.Sc in Biotechnology.



Projects/Research:1. Construction and characterization of cDNA library of Plantagoovata.2. Regulation of the turn over of mitotic cyclins and their role in the development of human malignancies.

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology program. (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.

Scientific Interests and Goals:My main field of interest is cell biology and oncology, I want to study cell cycle and its regulation . I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology.

Hobbies and other interests:Music, Movies, literature, etc.

First name:Sangeeta

Last name:Chauhan


Country:India


Supervisor:Dr. N.P. MalekMolecular Biology

EducationCollege/University:1999-2003 BSc. in Biological Science, Ningbo University, China2003-2004 MSc. in Molecular Genetics, the University of

Leicester, UK

Highest degree:MSc. in Molecular Genetics

Major Subjects:Genetics, Biochemistry and cellular biology

Projects/Research:The function of PDZ domain proteins in ion transport and the signal pathways by regulated cytoproteins.

Scientific Interests and Goals:To identify certain signal pathways on ion transport and their different physiological affection on ion absoption and secretion.

Hobbies and other interests:Relaxing and lying on somewhere with cool soft drinks and wonderful performance.

First name:Mingmin

Last name:Chen


Country:China


Supervisor:Prof. SeidlerGastroenterology, Hepatology & Endocrinology

EducationCollege/University:1997-2000 Bachelor of Science (Microbiology)

Osmania University, Hyderabad, India2001-2003 Master of Science (Biotechnology)

MKU, Madurai, India

Highest degree:Master of Science: Biotechnology


Projects/Research:Constitutive and induced antigen presentation of exogenous antigens by dendritic cells

Scientific Interests and Goals:To gain clear understanding into the underlying events occurringin the immune system with an aim to modulate the immune responses and directing them efficiently towards the infections.

Hobbies and other interests:Music, Cricket

First name:Prajeeth

Last name:C.K


Country:India

E-mail:[email protected], [email protected]

Supervisor:Prof BehrensClinical Immunology

EducationCollege/University:1998-2000 University of Greifswald, Germany2000-2002 University of Heidelberg, Germany2003 Diploma in Pharmacy

(University of Greifswald)

Highest degree:Dipl. pharm.

Major Subjects:Immunology, Human genetics

Projects/Research:Genetic risk factors of autoimmune diseases: Multiple Sclerosis, Sjögren’s syndrome and Systemic lupus erthematosus

Scientific Interests and Goals:My main interest is to study new targets and the development of therapeutics.

Hobbies and other interests:singing, guitar, meeting with friends, cinema

First name:Gamze

Last name:Kabalak


Country:Germany


Supervisor:PD Dr. med. WitteClinical Immunology

EducationCollege/University:1998-2000 M.Sc. In Biotechnology, HPU, Shimla, India.2001-2002 Diploma in Bioinformatics, JNU, Delhi, India.

Highest degree:M.Sc. in Biotechnology, Advanced Diploma in Bionfomatics

Major Subjects:Biotechnology and Computational Biology

Projects/Research:To unravel Telomeres and Telomerase activity in Bovine Embryos and Stem cells

Scientific Interests and Goals:To execute innovative and value-added research

Scholarships:Research Fellowsip by Council for Scientific and Industrial Reseach (CSIR), ICMR and Department of Biotechnology, India.

Hobbies and other interests:Travelling, Movies, Reading and Exploring „The Deutschland“.

First name:Khursheed

Last name:Iqbal


Country:India


Supervisor:Prof. Dr. Niemann

Department ofBiotechnology,Institute of Animal Sciences (FAL), Mariensee

EducationCollege/University:1996-1999 Bachelor of Science Honours Degree in

Biochemistry,University of Zimbabwe, Zimbabwe2002-2004 Master of Science Degree in Molecular Biology ,

Vrije Universiteit Brussel, Belgium

Highest degree:MSc in Molecular Biology

Major Subjects:Biochemistry and Molecular Biology

Projects/Research:Antigen-specific regulatory T-cells for control of auto- and alloimmune responses

Scientific Interests and Goals:To understand the molecular basis of human diseases and to apply this knowledge in the developmemnt of new therapies.

Hobbies and other interests:Traveling, Reading, Singing, meeting new people and learningabout new cultures

First name:Nonsikelelo

Last name:Mpofu


Country:Zimbabwe


Supervisor:Dr. JaeckelGastroenterology, Hepatology & Endocrinology

EducationCollege/University:1997 Jomo Kenyatta University of Agriculture and Technology-

Kenya, BSc(Biochemistry and Chemistry)

2003 University of Nairobi –Kenya MSc in Biochemistry

Highest degree:MSc in Biochemistry

Major Subjects:Biochemistry

Projects/Research:Farnesyl Transferase Inhibitor (FTI) Modulation of Topoisomerase

IIα Inhibition efficacy in Myloid Leukemia

Scientific Interests and Goals:Interested in Biological Signalling and its role in controlling

disease

Hobbies and other interests:Long distance Running, Eating free food, Arguing and Sleeping

Publications:Graham SP, Pelle R, Honda Y, Mwangi DM, Tonukari NJ, Yamage M, Glew

EJ, de Villiers EP, Shah T, Bishop R, Abuya E, Awino E, Gachanja J, Luyai AE, Mbwika F, Muthiani AM, Ndegwa DM, Njahira M, NyanjuiJK, Onono FO, et al. Theileria parva candidate vaccine antigensrecognized by immune bovine cytotoxic T lymphocytes. Proc Natl AcadSci U S A. 2006 Feb 21; [Epub ahead of print]

First name:Fredrick Onyango

Last name:Onono


Country:Kenya


Supervisor:PD Dr. ReuterHematology and Oncology

EducationCollege/University:1992-1998 MD National Medical University of Mongolia1999-2001 MSc Medical Genetics NMUM

Highest degree:MD, MSc

Major Subjects:Medical Genetics, Cell Biology

Projects/Research:ErB4 in fetal surfactant synthesis

Scientific Interests and Goals:To study molecular and cellular aspects of prenatal and postnatal disorders, to contribute to the development of biomedicalresearch in my country.

Hobbies and other interests:Sports, Travel

First name:Erkhembulgan

Last name:Purevdorj


Country:Mongolia


Supervisor:Dr. DammannPediatric Pulmonologyand Neonatology

EducationCollege/University:1999-2002 BSc (Hons.) Microbiology,Gargi College, Delhi

University, New Delhi, India2002-2004 MSc Biotechnology, AIIMS, New Delhi, India

Highest degree:MSc Biotechnology

Major Subjects:Microbiology, Immunology, Molecular Biology

Projects/Research:Analysis of the sequence of telomere dysfunction followed by telomerase activation during aging and carcinogenesis

Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics

Hobbies and other interests:Reading, Philately, Numismatics, Origami

First name:Aaheli

Last name:Roy Choudhury


Country:India


Supervisor:Dr. K. L. RudolphGastroenterology, Hepatology& Endocrinology

EducationCollege/University:1998-2004 TFH-Berlin, Germany 2002 Dublin City University, Ireland2003 Baylor College of Medicine, Houston, TX, USA

Highest degree:Dipl. Ing. (FH)

Major Subjects:Pharmaceutical & Chemical Engineering

Projects/Research:Interaction between the p38 MAP kinase signaling cascade and Polycomb group proteins:Analysis of function and structure of MK2-Edr Polycomb complexes.

Scholarships:Grant from Hannover Biomedical Research School

Hobbies and other interests:Sports and travelling

First name:Jessica

Last name:Schwermann


Country:Germany


Supervisor:Prof. Dr. M. GaestelPhysiologicalChemistry

EducationCollege/University:2001- 2003: Master of Science in Biotechnology: MaduraiKamaraj University, Madurai., India.1998- 2001: Bachelors óf Science ( Chemistry): VanasthaliVidyapith, Rajasthan, India.

Highest degree:Master of Science, Biotechnoligy.

Major Subjects:Biochemistry, Molcular Biology, Immunology, Plant Biotechnology, Animal Biotechnology.

Projects/Research:Structural-Functional analysis of cis-acting elements required formRNA stability.

Scientific AchievmentBest poster award on Ćharacterization of DNA Gyrasemodulatory activity of Glutamate Racemase from Mycobacteriatuberculosis.Sugopa Sengupta, Meera Shah, V Nagaraja. in ITREID ( transcriptional meeting), 2005.

Scientific Interests and Goals:To get further insights to the proteins involved which areresponsible for mRNA regulation.

Hobbies and other interests:Music, dance, Reading, interest lies in doing science.

First name:Meera

Last name:Shah

Date of birth:03. 05. 1980

Country:INDIA


Supervisor:Prof. Helmut HoltmannInstitute of PhysiologicalChemistry

EducationCollege/University:1999-2002 B.Sc. Hons. In Chemistry Banaras Hindu University,India2002-2004 M.Sc. Biotechnology, Madurai Kamaraj University,

India

Highest degree:M.Sc. In Biotechnology


Projects/Research:Elucidation of molecular mechanisms of Helicobacter VacA toxin.

Hobbies and other interests:Playing Games (table tennis, cricket), listening to music

First name:Anurag

Last name:Kumar Singh


Country:India

E-mail:[email protected] [email protected]

Supervisor:Prof. Ursula SeidlerGastroenterology, hepatology and Endocrinology

EducationCollege/University: Bsc,Poorvanchal University

Highest degree:M.Sc, JNU, New Delhi


Projects/Research:1. Structural and functional study of Actin binding proteins2. Cloning and expression of recombinant GMCSF in E. coli

Plasmid stability of GM-CSF gene in diff vectorsCenter For Biotechnology JNUSupervisor: KJ Mukherjee Associate Professor JNU

3. Cell BiologyMaintainance of Macrophage,Lymphocyte and Tcell linesMaintaince of entamoeba cell linesWorked with vibrio strains and also some experiments on

proteases

Scientific Interests and Goals: To go into infection biology feild.

Hobbies and other interests:Music .

First name:Leena

Last name:Srivastava


Country:India


Supervisor:Dr.Elena KorenbaumBiophysical Chemistry

EducationCollege/University:M.Sc Biotechnology from School of Biotechnology, Madurai Kamaraj University

Highest degree:M.Sc Biotechnology

Major Subjects:Molecular Biology, cell biology, biochemistry and biotechnology.

Projects/Research:An approach towards structural determination of Cardamon mosaic virus.To generate SYMV resistance in Soybean crops using siRNA mediated gene silencing.

Scientific Interests and Goals:To do basic research in the field of cell and molecular biology. Post-transcriptional gene regulation.

Hobbies and other interests:Travel and Cricket

First name:Basant Kumar

Last name:Thakur


Country:India


Supervisor:Prof. HoltmannPhysiological Chemistry

EducationCollege/University:1995-2002 Humboldt University Berlin, Medical Faculty

Charitè, Germany

Highest degree:MD

Major Subjects:Molecular- and Cell Biology, Differentiation

Projects/Research:Differentiation and Proliferation Control by Wnt and BMP Signaling Cascades in Thyroid Cancer

Scientific Interests and Goals:Understanding the Molecular Basis of Multicellularity, Differentation and Tumorigenesis. My Goal is to use a Hybrid approach with Standard Laboratory Techniques Guided byTheoretical Models to Understand Genomic Complexity of Health and Disease.

Hobbies and other interests:Fine art, Cooking/Sushi, Programming, My Collection of SeaShells, Machine Intelligence, History of Science.

Publications:Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Biochim Biophys Acta 1998 19; 1448(1): 157-52 Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Ann N Y Acad Sci 1999 20;885:448-450Ohnemus U, Uenalan M, Handjiski B, Paus R J Invest Dermatol 2003 122(1): 7-13Ohnemus U, Uenalan M, Conrad F, Handjiski B, Mecklenburg L, Nakamura M, Inzunza J, Gustafsson JA, Paus R Endocrinology 2004, epub

First name:Murat

Last name:Ünalan


Country:Germany


Supervisor:Prof. Brabant,Endocrinology

EducationCollege/University:1997-2001 Huazhong Agricultural University, P.R.China2001-2004 Wuhan Institute of Virology, Chinese Academy of

Sciences

Highest degree:Master of Science

Major Subjects:Tumor immunology

Projects/Research:Identification of a dominant antigen of the murine pancreatic

tumor by SEREX, and characterize the antigen

Scientific Interests and Goals:Tumor research

Hobbies and other interests:Travelling and Movies.

First name:Fei

Last name:Zhao


Country:P.R.China


Supervisor:PD. Dr. med. Tim F. GretenGastroenterology, Hepatology& Endocrinology

year 2005

Mathias Christgen

Priyanka Dutta

Ursula Ehmer

Luis Guachalla Gutierez

Lydia Asrat Haile

Harshvardhan

Henoch Hong

Ananta Paine

Amrita Rai

Sumit Rathore

Mathias Rhein

Reena Singh

Inga Sörensen

Ratnesh K. Srivastav

Ujala Srivastava

Kathrin Steinwede

Shazad Nawaz Syed

Dong Wang

Alexander Wolf

Katja Zscheppang

EducationCollege/University:2004-2005: University Kiel, Germany, Institute of Pathology, Clinical Training (PJ).2003-2004: Howard Hughes Medical Institute, Cleveland, U.S.A., Research Scholar in Cancer Genetics.2000-2003: University Kiel, Graduate Student in Medicine. 1998-2000: University Halle, Germany, Undergraduate Student in Medicine.

Highest degree:M.D


Projects/Research:Isolation of characterization of clonogenic breast cancer cells

Awards & Scholarships:2003: Scholarship of the German Academic Exchange Service.2002: Abraham-Buschke-Award of the Charité Berlin.2001: Scholarship of the „Studienstiftung“.1995: Jugend-Forscht-Award in chemistry.

Scientific Interests and Goals:Yo Berra, an American baseball star of the 1950ties, once said: “What gets us into trouble is not what we don‘t know. It‘s what we know for sure that just ain‘t so.“ In my opinion, this pertains to science, too. Hence, it is my goal, that our research on epithelial malignancies truly tackles the nature of cancer.

Hobbies and other interests:Soccer, funk music and cross country skiing.

PublicationsFrom previous work

First name:Matthias

Last name:Christgen


Country:Germany


Supervisors:PD. Dr. Lehmann / Prof. Dr. Kreipe, Institute of Pathology

EducationCollege/University:2003-2005 All India Institute for Medical Sciences (AIIMS)



Projects/Research:1. Further characterize the contribution of p53 to cytokine receptor mediated signaling and cellular phenotype in 32Dwt and 32D p53hypo cells. 2. Elucidate cellular components involved in myeloiddifferentiation

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2003-2005).

Scientific Interests and Goals:My main field of interest is Haematopoesis, I want to study thebiology of the haematopoetic cytokine receptor signalling. I would consider myself to be successful in my ambition if I am inany way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology better.

Hobbies and other interests:Music, books, Movies, literature, etc.

First name:Priyanka

Last name:Dutta


Country:India


Supervisor:Prof. Scherr/Prof. EderHaematology

EducationCollege/University:1997-2004 Hannover Medical School

Highest degree:MD

Major Subjects:Gastroenterology and hepatology, human genetics, metabolism

Projects/Research:Identification of functional relevant single nucleotide polymor-phisms in drug metabolizing enzymes (UDP-glucuronosyltrans-ferases, UGT). Regulation studies on UGT in a transgenic mouse model

Scientific Interests and Goals:Molecular genetics, impact of genetic polymorphisms on metabolism, regulation of metabolic enzymes.

Hobbies and other interests:Reading, sports, travelling, cooking.

Publications:Ehmer U, Vogel A, Schütte JK, Krone B, Manns MP, Strassburg CP. Variation of hepatic glucuronidation: novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. Hepatology, 2004; 39(4): 970-977

Vogel A, Ockenga J, Ehmer U, Barut A, Kramer FJ, Tukey RH, Manns MP, Strassburg CP. Polymorphisms of the carcinogen detoxifying UDP-glu-curonosyltransferase UGT1A7 in proximal digestive tract cancer. Z. Gastroenterol. 2002, 40(7): 497-502

Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, Strassburg CP. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 2001; 121: 1136-1144

First name:Ursula

Last name:Ehmer


Country:Germany


Supervisor:PD Dr. C. S. StrassburgGastroenterology, Hepatology and Endocrinology

EducationCollege/University:1998-2002 Universidad Mayor de San Andres. Licenciado in Biochemistry2004-2005 University of Westminster. MSc in MedicalBiotechnology

Highest degree:M.Sc. in Medical Biotechnology


Projects/Research:1. Analysis of the role of stanniocalcins genes and apoptosispathways during cellular and organismal ageing.

Scholarships:1. Full International Scholarship awarded by the University of Westminster. London, UK (2004-2005).

Scientific Interests and Goals:The understanding and elucidation of ageing mechanisms in invitro and in vivo systems.

Hobbies and other interests:Music, athletics.

First name:Luis Miguel

Last name:GuachallaGutierrez


Country:Bolivia


Supervisor:PD. Dr. med Lenhard Rudolph

EducationCollege/University:2001-2003 National Institute of Pharmaceutical Education and Research, M.Sc in Pharmacology.

Highest degree:M.Sc. in Pharmacology

Major Subjects:Pharmacology

Projects/Research:T cell based therapies in mouse model of colitis associatedColon cancer

Scientific Interests and Goals:To get further insights in to the molecular causes of diseases.

Hobbies and other interests:Music, Movies, travelling

Publications:Srinivasan K, Viswanad B, Asrat L, Kaul CL, Ramarao P. Combination of high-fat diet fed and low dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.Pharmacol Res.2005 Oct;52(4):313-20.

First name:Lydia

Last name:Haile


Country:Ethiopia


Supervisor:PD. Dr. Tim GretenGastroenterology

Education2002-2004; Masters in Life Sciences from Jawaharlal Nehru University (JNU), New Delhi.2004-2005; Doctoral student at Indian Institute of Science (IISc), Bangalore.

Highest Degree:M.Sc. in Life Sciences.

Major Subjects:Molecular Cell Biology and Immunology.

Projects/Research:1. Survival of syngenic and xenogenic erythrocytes in mice, Immune functioning and modulation.2. Initiation of replication in single stranded positive sense RNA viruses.

Scholarship:Junior Research Fellowship (JRF-NET) awarded by Council forScientific and Industrial Research (CSIR), India.

Scientific Interests and Goals:I am interested in induction of aging and its molecluar aspects.The main mediators of aging are the immune system and the Nervous system or Brain. In the past time the average age of human being has increased continously and so the incedences of age related disordes like Parkinsons disease and Alzehimers disease that target Brain; have also increased parallely. My work is focused on the induction of aging and ist effect on development and progression of such disorders.

Hobbies and other interests:Music, Cricket, Movies and Poetry.

Name:Harshvardhan

Date of Birth:01.01.1982

Country:India


Supervisor:Dr. Lenhard K. RudolphDept. of Gastroenterology, Hepatology and Endocrinology.

EducationCollege/University:2000-2005 University of Heidelberg in Biology.2004-2005 Diploma Thesis at the DKFZ (German CancerResearch Center)

Highest degree:Diploma in Biology

Major Subjects:Molecular Biology, Cell Biology, Biochemistry

Projects/Research:Study how HIV-1 affects and impairs the innate immunityfocusing on natural killer cells and dendritic cells; establishing an in vitro model for the interaction of highly purified dendritic cellsand natural killer cells

Scientific Interests and Goals:Immunology and Virology are my main fields of interest.

Hobbies and other interests:Playing piano, Basketball, Christian Literature, Cooking and Eating etc.

First name:Henoch Sangjoon

Last name:Hong


Country:Germany


Supervisor:Prof. Dr. Schmidt/Dr. med HeikenClinical Immunology

EducationCollege/University:2002-2004 University of Pune , M.Sc. in Bioinformatics

Highest degree:M.Sc. in Bioinformatics

Major Subjects:Bioinformatics

Projects/Research:Identification of immunotherapeutically targetable peptide

antigens for individualized leukemia treatment .

Scholarships:G.N. Ramchandran Scholarship , awarded by CBT, India (2002-

2004).

Scientific Interests and Goals:My areas of interest are immunology and cancer reseach . As a scientist my dream is to find effective treatments for various

infectious and systematic diseases .

Hobbies and other interests:Painting, movies, music, literature .

First name:Ananta

Last name:Paine


Country:India

E-mail:anantapaine24@@yahoo.com

Supervisor:Prof Dr. Britta Eiz Vesper Institute for Transfusion Medicine

Education

College/University:1999-2002 Banaras Hindu University, B.Sc. (Hons) in Chemistry2002-2004 Indian Institute of Technology Roorkee, Roorkee M.Sc. in Biotechnology.

Highest degree:M.Sc.


Projects/Research:

1. Structure and function of Dynamin and Dynamin Related Proteins.2. Worked as J.R.F at National Centre for Cell Science,Pune India. I was working on project “ Differentiation of mouse embryonic stem cells (mES)

into Pancreatic ß cell like clusters (2004-05)”.3. Project work on “ Studies on acid and salt tolerance of Rhizobial strains

isolated from legumes(2004)”.4. Worked on cloning ,expression and characterization of phosphoenol pyruvate carboxylase,UV survival and thermoluminescence of wild and mutants of Anacystis nidulans (2003).

Scholarships:

1. Junior Research Fellowship (JRF) awarded by Council for Scientific and Industrial Research (CSIR), India. Among top 20%2. Qualified Graduate Aptitude Test in Engineering (GATE). All India Rank 563. Received Biotechnology Scholarship for Masters (2002-04),it was sponsored by DBT ,India.

Scientific Interests and Goals:To learn more about Dynamins.

Hobbies and other interests:Music , Dress designing and Roaming.

First name:Amrita

Last name:Rai

Date of birth:15-07-1980

Country:India


Supervisor:Prof. D.J.MansteinBiophysical Chemistry

EducationCollege/University:2002-2004 All India Institue of Medical SciencesM. Biotechnology



Projects /Research:1. Development of muatnt and standard clone from 5‘UTR of Hepatitis C virus towards the development of quantiative PCR assay2. Production , purification , chracterization of Rv 1984c fromM.Tuberculosis

Scholarships:1. Awarded by DBT,India for selection in All india combined M.Sc. Biotechnology programe (2002-2004).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.

Scientific Interests and Goals:My main field of interest is Immunology, I want to study the role of granulocytes and the pathways of there apoptosis. I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us to understand thisfascinating area of biology better.


First name:Sumit

Last name:Rathore


Country:India


Supervisor:Prof. Bettina WediDermatology

EducationCollege/University:1999-2004 Johann Wolfgang Goethe University of Frankfurt

Highest degree:Diploma of Biochemistry

Major Subjects:Biochemistry, Biophysical Chemistry

Projects/Research:1. Mouse models for neurotrophin receptor- induced leukemia2. Functional analysis of deregulated neurotrophin receptoractivation in leukemia3. Validation of potential therapeutic approaches to treatneurotrophin- induced leukemia

Scholarships:PhD stipendship of the German Jose Carreras LeukemiaFoundation (Deutsche Jose Carreras Leukämie- Stiftung)

Scientific Interests and Goals:My scientific focus is leukemia. We try to understand the basicmechanisms that lead to leukemogenesis through oncogenicderegulation of neurotrophin receptors. The goal is to utililzemouse models for the discovery of new therapeutic approaches to treat human neurotrophin- related leukemia.

Hobbies and other interests:Music(guitar), Aikido, english language, sports

First name:Mathias

Last name:Rhein


Country:Germany


Supervisor:Prof. Dr. C. BaumDr. Zhixiong Li

Experimental CellTherapy, Department of Hematology, Hemostaseology and Oncology

First name:Reena

Last name:Singh


Country:India



EducationCollege/University:2003-2005 Madurai Kamaraj University



Projects/Research:1. Study of expression of pigmentation genes in skin and their

functional role in melanogenesis.2. Cloning of Thaumatin like protein and Chitinase gene in binary

vector and transformation of indica rice variety White Ponni to enhance sheath blight resistance.

Scholarships:1. Fellowship awarded by DBT,india for selection in All india

combined M.Sc. biotechnology programme (2003-2005).2. Junior Research Fellowship (JRF) awarded by Council for

Scientific and Industrial Research (CSIR), India (2005).

Scientific Interests and Goals:My main field of interest is Developmental Biology, I want to

investigate role of T-box genes during heart development.

Hobbies and other interests:Music, dance, love to be in the laps of nature,

EducationCollege/University:2000-2005 University of Applied Sciences Hamburg

Highest degree:Diploma in Biotechnology

Major Subjects:Biotechnology:Applied Micro-and Molecular Biology

Projects/Research:1. Expression, Purification and Characterisation of the bacteriocinpediocin PA-1 from Pichia pastoris (BRI, National Research Council of Canada, Montreal)2. Lesion induced plasticity in the spinal cord of adult zebrafish (dDiploma thesis, Center of Molecular Neurobiology Hamburg)3. Role of the Notch ligand Delta-like-1 in cardiovascularregeneration.

Scholarships:1. Karl-Heinz-Ditze Stiftung: full scholarschip for studyingabroad2.Scholarship from DAAD for study expenses in Canada.

Scientific Interests and Goals:My main field of interest is regeneration in different complexsystems and model organisms. I want to study which genes areinvolved and which role they play in cardiovascular regnerationand angiogenisis. I would like contribute a small step to thedevelopment of new therapies for cardiovascular diseases in humans.

Hobbies and other interests:Hockey (UHC Hamburg, now Hannover 78), Fitness, Traveling

Publications:under submission

First name:Inga

Last name:Sörensen


Country:Germany


Supervisor:Dr. F.P. LimbourgMolecular Cardiology

EducationCollege/University:2001-2003 Madurai kamaraj University M.Sc in Biotechnology.



Projects/Research:1.Expression, refolding and purification of ßketo acyl ACP reductase an indespansible enzyme of Fatty acid biosynthesisof plasmodium.2.Cloning, subcloning and expression of PKS antibiotics in E.coliexpression system.3. Refolding and purification of C and Z sigma factor of Micobacterium tuberculosis.

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.3. R&D Assistantship from JNCASR, Bangalore, India.4. 40th rank in GATE coducted by Indian institute of technology India in 2003.

Scientific Interests and Goals:My main field of interest is Developmental Biology, I want to study the biology of Somite and Limb Patterning.


First name:Ratnesh

Middle nameKumar

Last name:Srivastav


Country:India



EducationCollege/University:1998-2001 Bachelors in Science from University of Lucknow,

Lucknow, India.2001-2003 Masters in Biochemistry from University of Lucknow,

Lucknow, India

Highest degree:M.Sc. in Biochemistry


Projects/Research:Production and characterisation of the Est1 knockout mouse and

the role of Rad9 in replicative senescence.

Scholarships & Awards:Prof. P.S. Krishnan gold medal for securing first position in

mastersCouncil for Scientific and Industrial research(CSIR) and Indian

council of Medical Research (ICMR) fellowship

Scientific Interests and Goals:The elucidation of senescence mechanisms in in vitro and in vivo

systems.

Hobbies and other interests:Music, Reading etc.

First name:Ujala

Last name:Srivastava


Country:India


Supervisor:PD. Dr. med Lenhard Rudolph

EducationCollege/University:2000-2005 University Bremen2005 Diploma in Biology (University Bremen)

Highest degree:Dipl. Biology

Major Subjects:Immunology, Microbiology

Projects/Research:Investigation of the role of lysosomal cathepsins in mycobacterialinfections of the lung

Scientific Interests and Goals:To understand the host immune response in engendering protective immunity against bacterial and viral infections and Iam also interested in the strategies of pathogens to evade the immune system. .

Hobbies and other interests:music, guitar, theatre, movies…

First name:Kathrin

Last name:Steinwede


Country:Germany

E-mail:[email protected]@MHH.de

Supervisor:PD Dr. MausPneumology

EducationCollege/University:1999-2000 MSc –I Botany (Nagpur University)2000-2002 MSc in Biochemitry (Nagpur University)

Highest degree:MSc (Biochemistry)

Major Subjects:Biochemistry, Biotechnology, Immunology

Projects/Research:1. “Establishment of COS cell Transfection and Erythrocyte Adhesion

Assay for Plasmodium vivax Erythrocyte Binding Protein”.2. “Standardization of AmpRT Assay using HIV-1 genome”3. Understanding the molecular mechanism, genetics and functional

genomics of insecticide resistance Helicoverpa armigera.

Scholarships:1. Qualified Indian Council for Medical Research exam for Junior

Research Fellowship (ICMR JRF), July 2003.2. PhD fellowship from GRK-705.

Scientific Interests and Goals:My focus in PhD research is Molecular Immunolgy. I would like to

decipher molecular regulation in autoimmune diseases withspecial emphasis on AIHA so that the knowledge can betranslated into effective therapeutic scheme.Only more research – result oriented, would help invigorate my curiosity and take me to an advanced stage of standpoint.

Hobbies and other interests:Outdoor Sports, Music,Technologies, etc.

First Name:Shahzad Nawaz

Last Name:Syed


Country:India


Supervisor:Prof. Dr. GessnerClinical Immunology

EducationCollege/University:1997-2002 Peking Union Medical College.

Highest degree:M.D.

Major Subjects:Immunology/Infectious Disease

Projects/Research:Pathogenic roles of keratinocytes in cutaneous lupuserythematosus.

Scholarships:Les Amis de Pasteur,Pasteur Institute of Brussels

Scientific Interests and Goals:Besides interests in Immunology/Infectious disease, I wouldelucidate the role of keratinocytes in the pathophysiology of lupus erythematosus especially the cross presentation of extracellular antigens to MHC-I restricted CD8 T cells.

Hobbies and other interests:Literature,History,Music,Econimy, Philosophy and Linguistic.

Publications:1.Wang D, Liu Baofeng. Malaria Vaccine, p.355-401.Vaccinology. Editor in chief: Zhang Yanling, Science Press of China, Beijng, PR China, 2004

2.Wang D, Mao YH, Wang H. Molecular cloning of P.y. dynamin-like protein PyDyngene and the immunological character of its domains. ACADEMIAE MEDICINAE SINICAE. 2003;25(2):176-80

First name:Dong

Last name:Wang


Country:China


Supervisor:Prof. WittmannDermatology

First name:

Alexander

Last name:

Wolf


Country:Germany

E-mail:alex.plasmid

@gmx.de

Supervisor:Prof. Kracht

Pharmacology

EducationCollege/University:1999-2004 University Hannoversince 2004 Medical School Hannover

Highest degree:Dipl. Biochemistry

Major Subjects:Biochemistry, Organic Chemistry, Pharmacology

Projects/Research:Analysis of the mechanism by which the yersiniaenterocolitica virulence factor Yop.P inhibits host cell protein kinases

Scientific Interests and Goals:to research the way like the virulence factor Yop.P caninhibit simultaenously several inflammation pathways

Hobbies and other interests:climbing, hiking, canoeing, travelling by bike, chess, Music

Publications:Tsikas D, Wolf A, Frolich JC. Simplified HPLC method for urinary andcirculating creatinine. Clin Chem. 2004 Jan;50(1):201-3.

EducationCollege/University:2000-2005 University of Applied Sciences, Senftenberg.

Highest degree:MSc in Biotechnology


Projects/Research:ErbB4 receptor activation, trafficking, and function in fetal lung type II cells

Scientific Interests and Goals:To get further insights in the mechanisms by which ErbBreceptors regulate processes of fetal lung maturation.

Hobbies and other interests:Meeting with friends, Movies, Reading

First name:Katja

Last name:Zscheppang


Country:Germany


Supervisor:Dr. DammannPediatric Pulmonologyand Neonatology

Faculty Jürgen Alves Zhixiong Li

Christopher Baum Robert Lindner

Armin Braun (Fraunhofer Inst.itut) Nisar Peter Malek

Jan Buer (GBF) Dietmar Manstein

Olaf Dammann Fritz Melchers

Matthias Eder Martin Messerle

Britta Eiz-Vesper Nils v. Neuhoff

Reinhold Förster Heiner Niemann (TiHo, Mariensee)

Matthias Gaestel Francoise Routier

Harald Genth Lenhard Rudolph

Engelbert Gessner Michaela Scherr

Achim Gossler Bernhard Schieffer

Florian Gunzer Brigitte Schlegelberger

Matthias Gunzer (GBF) Reinhold Ernst Schmidt

Carlos Alberto Guzmann (GBF) Jörg Schmidtke

Hermann Haller Thomas F. Schulz

Hansjörg Hauser (GBF) Reinhard Schwinzer

Hans Heiken Ursula Seidler

Denise Hilfiker Axel Seltsam

Helmut Holtmann Beate Sodeik

Peter Horn Jürgen Strehlau

Roland Jacobs Manfred Stuhrmann-Spangenberg

Elmar Jaeckel Burkhard Tümmler

Christine Josenhans Ernst Ungewickell

Ingo Just Claus Urbanke

Andreas Kispert Jürgen Wehland (GBF)

Christoph Klein Siegfried Weiss (GBF)

Andreas Klos Eva Weissinger

Alexey Kotlyarov Karl H. Welte

Hans Kreipe Thomas Werfel

Norbert Krug (Fraunhofer Institut) Miriam Wittmann

Ulrich Lehmann Anna M. Wobus (IPK Gatersleben)

Andreas Lengeling (GBF)

Department and function:Professor, Biophysical Chemistry

Education:1975 – 1981 University of Hannover, Biochemistry1981 – 1984 PhD thesis

Positions:1984 – 1990 Postdoc Hannover Medical School1990 – 1995 PD Hannover Medical School1995 - Prof. Hannover Medical School

Major research interests:Protein design using different model systems:• Restriction endonuclease EcoRI• IS1 Transposase• Helikase I• DynaminCircular Dichroism Spectroscopy

Selected Publications:Windolph S, Fritz A, Oelgeschlaeger T, Wolfes H, Alves J. Biochemistry 1997; 36: 9478-9485.Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. J Biol Chem 2002, 277:8209-16.Scheele U, Alves J, Frank R, Duwel M, Kalthoff C, Ungewickell E. J Biol Chem. 2003; 278(28):25357-68.Fritsche P, Alves J. Biol Chem. 2004; 385(10):975-85

First name:Jürgen

Last name:Alves

Acad. Title:Prof. Dr. rer. nat.

Address:OE 4350Hannover Medical School

Phone and e-mail:++49-0511-532 [email protected]

Further information:http://www.mh-hannover.de/institute/bpc

Department and function:Professor, Hematology and Oncology

Education:1981-1982 Philosophy1982-1989 Medicine

Positions:1989-1991 Research Clinics, Borstel b. Bad Oldesloe1991-1992 Toxicology, Univ. of Hamburg1993-1999 Heinrich-Pette-Institute Hamburg 2000 University Hospital Eppendorf, Hamburg2000 - MHH, Dept. Hematology and Oncology2002 Cincinnati Children‘s Hospital Adjunct Position

Major research interests:Cell Therapy, Gene Transfer and TherapyRetroviruses, Gene expressionStem Cell BiologyBiology of cell selection and clonal evolution

Oncogenesis

Selected Publications:Schieldmeier B, et al. Blood 2003, 101:1759-1768.Baum C, et al. Blood 2003, 101:2099-2114.Williams DA, Baum C. Science. 2003; 302(5644):400-1. Engels B, et al. Hum Gene Ther. 2003; 14(12):1155-68Li Z, et al. Exp Hematol. 2003; 31(12):1206-14Baum C, et al. Mol Ther. 2004; 9(1):5-13.Werner M, et al. Gene Ther. 2004; 11(12):992-1000Klein C, Baum C. Hematol J. 2004;5(2):103-11Williams D, Baum C Nature. 2004; 429(6988):129Frank O, et al. Blood. 2004; 104(12):3543-9.Kraunus J, et al. Gene Ther. 2004; 11(21):1568-78.Galla M, et al. Mol Cell. 2004; 16(2):309-15. von Kalle C, et al. Semin Hematol. 2004; 41(4):303-18.Modlich U, et al. Blood. 2005; 105(11):4235-46.Kustikova O, et al. Science. 2005; 308(5725):1171-4.Klump H, et al. Ann N Y Acad Sci. 2005; 1044:6-15.Schambach A, et al. Mol Ther. 2006 Feb;13(2):391-400.Schambach A, et al. Gene Ther. 2005 Dec 15;Baum C, et al. Hum Gene Ther. 2006 Feb 8

First name:Christopher

Last name:Baum

Acad. Title:Prof. Dr. med.Adjunct AssociateProf. of Pediatrics



Further information:www.mh-hannover.de/kliniken/haemonko/cb_research.htm

Department and function:Head of Immunology and Allergology, Fraunhofer Institute of Toxicology and Experimental Medicine

Education:1998 PhD in Immunology, Humboldt-University

Berlin

Positions:1999-2001 Scientific Assistant (“post doc”), Prof. Dr. Renz,

Department of Clinical Chemistry, Philipps University Marburg, Germany

2001- Head of Immunology and Allergology, Fraunhofer Institute of Toxicology and Experimental Medicine

Major research interests:Neuro-immun Interaction in asthmaAnimal models of asthmaLung infection modelsImmunotoxicology

Selected Publications:C. Nassenstein, A. Braun, V.J. Erpenbeck, M. Lommatzsch, et al. J Exp Med. 2003; 198:455-467.A. Braun, M. Lommatzsch, U. Neuhaus-Steinmetz, D. Quarcoo, H. Renz. Br J Pharmacol. 2004;141:431-440H. Weigt, P.F. Muhlradt, M. Larbig, N. Krug, A. Braun. J Immunol. 2004; 172(10):6080-6.U. Forssmann, I. Hartung, R. Bälder, S.E. Escher, et al. J Immunol. 2004; 173(5):3456-66..R. Bälder, B. Fuchs, W. Bautsch, J. Zwirner, et al. J. Immunol. 2005; 174(2):783-9.Schulte-Herbruggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H, Braun A. J Neuroimmunol. 2005;160(1-2):204-9Weigt H, Nassenstein C, Tschernig T, Muhlradt PF, Krug N, Braun A. Am J RespirCrit Care Med. 2005;172(5):566-72.Lommatzsch M, Quarcoo D, Schulte-Herbruggen O, Weber H, Virchow JC, Renz H, Braun A. Int J Dev Neurosci. 2005;23(6):495-500.Nassenstein C, Schulte-Herbruggen O, Renz H, Braun A. Eur J Pharmacol. 2006 Feb 1

First name:Armin

Last name:Braun

Acad. Title:Dr.

Address:Nikolai-Fuchs-Str. 130625 Hannover

Phone and e-mail:+49 511 5350 [email protected]

Further information:www.item.fraunhofer.de

Department and function:Professor, Mucosal Immunity, GBF

Education:1987-1994 Medicine in Hannover and New York, 1995 Approbation, Doctor of Medicine, 2001 Habilitation in Immunology,

Positions:1998-present Head of Mucosal Immunity (GBF), 1998-present Institute of Medical Microbiology (MHH), 1996-1998 DFG-Fellowship in Immunology, Hôpital Necker-

Enfants Malades, Paris, France,1995-1996 Resident in Internal Medicine, Department of

Hematology and Oncology (MHH),

Major research interests:My current work on mucosal immunity concentrates on functional genomics of regulatory T cells in transgenic mouse models and patients with autoimmunity and inflammation. Other interests are Host-Pathogen-Crosstalk and Molecular Diagnostics.

Selected Publications:Lechner O, Lauber J, Franzke A, Sarukhan A, von Boehmer H, Buer J. Curr. Biol. 2001; 11: 587-595.Buer J, Balling R. Nature Reviews Genetics 2003; 4: 195-205.Franzke A, Piao W, Lauber J, Gatzlaff P, Konecke C, et al. Blood. 2003; 102:734-9.Matussek A, Lauber J, Bergau A, Hansen W, et al. Blood. 2003; 102(4):1323-32.Walter U, Toepfer T, Dittmar KE, Kretschmer K, et al. Diabetologia. 2003; 46(8):1106-14Bruder D, Probst-Kepper M, Westendorf AM, Geffers R, et al. Eur J Immunol. 2004; 34(3):623-30Bruder D, Westendorf AM, Geffers R, Gruber AD, et al. Am J Respir Crit Care Med. 2004; 170(11):1145-52Westendorf AM, Templin M, Geffers R, Deppenmeier S, et al. Gut. 2005; 54:60-9.Ma HW, Kumar B, Ditges U, Gunzer F, Buer J, Zeng AP. Nucleic Acids Res. 2004; 32(22):6643-9.Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS Microbiol Lett. 2005; 242(2):287-95Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von BoehmerH, Mahnke K, Buer J. Diabetes. 2005 Dec;54(12):3395-401.

First name:Jan

Last name:Buer

Acad. Title:Prof. Dr. med.

Address:GBF-MIMascheroder Weg 138124 Braunschweig

Phone and e-mail:[email protected]

Further information:www.gbf.de

Department and function:Head, Perinatal Infectious Disease Epidemiology UnitObstetrics, Prenatal Medicine, and General GynecologyPediatric Pulmonology and Neonatology

Education:1981-83 Linguistics, U of Hamburg, 1983-90 Medicine, Med U of Lübeck and U of Hamburg,

Epidemiology,1996-97 Harvard School of Public Health,

Positions:1991-95 Post-Doc, Pediatrics, U of Hamburg1995-97 Post-Doc, Neuroepidemiology, Children‘s Hospital,

Boston,1997-2000 Instructor in Neurology, Harvard Med School,since 2000 Assistant Professor in Neurology, Harvard Med School, since 2002 Professor of Perinatal Infectiology, Hannover Med.

School

Major research interests:Epidemiologic research on the role of infection and inflammation in theetiology and pathogenesis of brain white matter damage in pretermnewborns

Selected Publications:Dammann O, Allred EN, Genest DR, Kundsin RB, Leviton A. Paediatric and Perinatal Epidemiology 2003;17:49-57.Dammann O, Drescher J, Veelken N. Developmental Medicine & Child Neurology 2003;45:148-51.Jung H, Neumaier Probst E, Hauffa BP, Partsch CJ, Dammann O. J Clin EndocrinolMetab. 2003; 88(10):4590-5.Dammann O, Leviton A. Ann Neurol. 2004;55(2):158-161.Dammann O, Allred EN, Van Marter LJ, Dammann CE, Leviton A. Pediatr Res. 2004; 55(2):319-325.Leviton A, Dammann O. Pediatr Res. 2004; 55(4):541-5Losch H, Dammann O. J Child Neurol. 2004; 19(5):318-22.Dammann O, Allred EN, Leviton A, Shen-Schwarz S, Heller D, Genest DR, Collins MH. Placenta. 2004; 25(10):788-96.Dammann O, Bartels DB, Berner R. Pediatr Infect Dis J. 2004;23(10):978-9Bartels DB, Kreienbrock L, Dammann O, Wenzlaff P, Poets CF. Arch Dis Child Fetal Neonatal Ed. 2005; 90(1):F53-9.Leviton A, Blair E, Dammann O, Allred E. J Pediatr. 2005; 146(1):123-7.Dammann O, Leviton A, Gappa M, Dammann CE. BJOG. 2005 Mar;112 Suppl 1:4-9.

First name:Olaf

Last name:Dammann

Acad. Title:Prof. Dr.med., M.Sc.

Address:OE6415Hannover Medical School

Phone and e-mail:++49-511- 532 [email protected]

Further information:http://www.mh-hannover.de/forschung/perinatalinfektiologie/index.htm

Department and function:Professor, Hematology/Oncology unit; Consultant Bone marrow transplantation

Education:1982-89 Study of Medicine, Homburg/S and

Frankfurt/M1990 Doctoral thesis1989-91 Research assistant and fellow Int. Med.1991-93 Research fellow Dana Farber Cancer Inst., Boston1993-2000 Research fellow Int. Med. Frankfurt + MHHSince 2001 Habilitation, consultant Int. Medicine

Positions:1991-1993 Dana Farber Cancer Institute, Boston1993-1996 Johann Wolfgang v.Goethe University

FrankfurtSince 1996 MHH

Major research interests:Signal transduction by cytokine receptors in myeloid cellsModels for myeloproliferative disorders and acuteleukemiaLentiviral gene transferRNA interference

Selected Publications:Scherr M, Battmer K, Blömer U, Schiedlmeier B, Ganser A, Grez M, Eder M. Blood2002, 99:709Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M.. Blood 2003, 101:1566Scherr M, Morgan MA, Eder M. Curr Med.Chem 2003, 10: 245Tiede A, Eder M, von Depka M, Battmer K, Luther S, et al. Gene Ther. 2003; 10(22):1917-25. Scherr M, Steinmann D, Eder M. Ann Hematol. 2004; 83(1):1-8.Scherr M, Battmer K, Dallmann I, Ganser A, Eder M. Oligonucleotides. 2003; 13(5):353-63.Scherr M, Eder M. Curr Opin Mol Ther. 2004; 6(2):129-35Scherr M, Battmer K, Schultheis B, Ganser A, Eder M. Gene Ther. 2005; 12:12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M. Blood. 2005 Nov 8;

First name:Matthias

Last name:Eder




Further information:http://www.mh-hannover.de/kliniken/haemonko/index.htm

Department and function:Professor, Institute for Transfusion Medicine

Education:1988 – 1993 Biology, University Greifswald1993 – 1996 PhD, Virology, MHH2003 W1-Professor for Immunogenetics, Institute for

Transfusion Medicine, MHH

Positions:1996-1999 Research Group Leader at the German Red Cross

Institute, Springe1999-2003 Research Group Leader, Institute for Transfusion

Medicine, MHH2003-recent W1-Professor for Immunogenetics, Institute for

Transfusion Medicine, MHH

Major research interests:• Minor histocompatibility antigens involved in GvL and GvHD• Antigen-specific cytotoxic T cells• Cell therapy• Expression of recombinant HLAs and proteins• Peptide sequencing

Selected Publications:Elsner HA, Bernard G, Eiz-Vesper B, de Matteis M, Bernard A, Blasczyk R. Tissue

Antigens. 2002; 59(2):139-141.Khattab B, Eiz-Vesper B, Ganser A, Hertenstein B, Blasczyk R. Ann Hematol 2004:

83: 107-113.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45 (6): 960-968.Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.

Immunogenetics 2004; 56: 83 - 88. Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.

Immunogenetics 2005; 56: 769-772.Eiz-Vesper B, Horn PA, Daubert C, Khattab B, Blasczyk R. Transfusion 2006; in

press.

First name:Britta

Last name:Eiz-Vesper


Address:OE 8355Institute for Transfusion MedicineHannover Medical School

Phone and e-mail:++49- 511- 532 [email protected]

Further information:www.mh-hannover.de/institute/transfusion

Department and function:Director, Immunology

Education:1981 Abitur, Gymnasium Pegnitz1988 DVM, Munich, Veterinary Faculty1988 - 1991 Ph.D. Thesis

Positions:1991-93 Postdoc, Insitute of Biochemistry, University of Munich1994-00 Research Associate, Max-Delbruck-Center for

Molecular Medicine, Berlin2000-01 Associate Professor for Experimental Surgery and

Immunology, University of Erlangen2001 – Director and Head, Institute of Imunology, Professor for

Immunology

Major research interests:Chemokines and chemokine receptors, role in lymphoid organorganogenesis and organization, development of immunology memory,cell migration, tumor metastasis

Selected Publications:Henning G., Ohl L, Junt T., Reiterer P., Brinkmann V., et al. J Exp Med 2001;194:1875Ohl L., Henning G., Krautwald S., Lipp M., Hardtke S., et al. J Exp Med 2003;197:1199Pabst O, Ohl L, Wendland M, Wurbel MA, Kremmer E, Malissen B, Forster R J Exp

Med. 2004; 199(3):411-6Pabst O, Herbrand H, Bernhardt G, Forster R. Curr Opin Immunol. 2004; 16:394-9.Misslitz A, Pabst O, Hintzen G, Ohl L, et al. J Exp Med. 2004; 200(4):481-91Ohl L, Mohaupt M, Czeloth N, Hintzen G, et al. Immunity. 2004; 21(2):279-88.Pabst O, Herbrand H, Worbs T, Friedrichsen M, et al. Eur J Immunol. 2005; 35:98-

107.Gunther K, Leier J, Henning G, Dimmler A, Weissbach R, Hohenberger W, Forster

R. Int J Cancer. 2005 Sep 20;116(5):726-33Hardtke S, Ohl L, Forster R. Blood. 2005 Sep 15;106(6):1924-31.Pabst O, Peters T, Czeloth N, Bernhardt G, Scharffetter-Kochanek K, Forster R. J

Immunol. 2005 Jun 15;174(12):7492-5.Czeloth N, Bernhardt G, Hofmann F, Genth H, Forster R. J Immunol. 2005;

175(5):2960-7.Pabst O, Herbrand H, Willenzon S, Worbs T, Schippers A, Muller W, Bernhardt G,

Forster R. J Immunol. 2006; 176(3):1474-80.

First name:Reinhold

Last name:Förster

Acad. Title:Prof. Dr. med. vet



Department and function:Director, Biochemistry (Physiological Chemistry)

Education:1983 PhD in Biology (Biophysics), Humboldt-University

Berlin1993 Habilitation in Biochemistry, Free University Berlin

Positions:1991-1995: Junior Research Group Leader at the Max-Delbrück-

Centrum for Molecular Medicine (MDC), Berlin-Buch1995-1997: Heisenberg-Fellow of the German Research Council

(DFG), Guest Research Group Leader at the MDC,Berlin-Buch

1997-2000: Professor of Molecular Genetics; Innovationskolleg"Zellspezialisierung" of the Martin-Luther-UniversityHalle-Wittenberg

2001-recent: Chair and Head of Institute of Biochemistry/ Physiological Chemistry of Hannover Medical School

Major research interests:Analysis of mechanisms of stress-dependent signal transductionNucleo-cytoplasmic signallingRegulation of gene expression by protein phosphorylation at the post-transcriptional level

Selected Publications:Kotlyarov A., Neininger A., Schubert C., Eckert R., Birchmeier C., et al. Nature Cell Biol. 1999; 1: 94-97.Neininger A., Thielemann H, Gaestel M. EMBO Rep. 2001; 2: 703-708.Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., et al. J. Biol. Chem. 2002; 277: 3065-3068.Kotlyarov A., Yannoni Y., Fritz S., Laaß K., Telliez J.-B., et al. Mol. Cell. Biol. 2002; 22: 4827-4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21): 7732-7741.Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M EMBO J. 2004; 23(24):4770-4779Gaestel M. Nat Rev Mol Cell Biol. 2006; 7(2):120-30.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006 Mar;26(6):2399-407.

First name:Matthias

Last name:Gaestel

Acad. Title:Prof. Dr.



Further information:www.mh-hannover.de/institute/biochemie

Department and function:Group leader, Department of Toxicology

Education:1998-95 Chemistry, Technical University of Darmstadt,

Germany 1995-2000 PhD in Chemistry, Albert-Ludwigs-Universität

Freiburg

Positions:2000-recent: Group leader, Institute of Toxicology/


Major research interests:Mode of action of bacterial protein toxinsSignal transduction pathways governed by Rho and Ras

Selected Publications:Genth, H., J. Selzer, C. Busch, J. Dumbach, F. Hofmann, K. Aktories, I. Just.. Infection and Immunity. 2000; 68: 1094-1101Genth, H., R. Gerhard, A. Maeda, M. Amano, K. Kaibuchi, K. Aktories, I. Just.. Journal of Biological Chemistry. 2003; 278:28523-28527.Gerhard,R., H. Tatge, H. Genth, T. Thum, J. Borlak, G. Fritz, I. Just.. Journal of Biological Chemistry 2005; 280(2):1499-505, 2005.Czeloth, N., G. Bernhardt, F. Hofmann, H. Genth, R. Foerster. Journal of Immunology 2005; 175(5):2960-7.

First name:Harald

Last name:Genth

Acad. Title:Dr. rer. nat.



Further information:www.mh-hannover.de/institute/toxikologie

Department and function:Group Leader, Laboratory of Molecular Immunology; ClinicalImmunology

Education:1993 PhD in Chemistry and Molecular Biology, Technical

University (TU) Berlin1999 Habilitation in Immunology, Hannover Medical School

Positions:1994-1996: Research Associate, Dept. of Clinical Immunology,

Hannover Medical School 1994: Visiting Scientist, Dept. of Immunology, University of

Utrecht, The Netherlands1997: EMBO Research Fellow, Dept. of Pathology, CMU

Geneva, Switzerland1997-recent: Research Group Leader, and from 2002 on, Scientific

Director and Head of the Laboratory of Molecular Immunology at the Department of Clinical Immunology, Hannover Medical School

Major research interests:I) Analysis of molecular mechanisms underlying immunoregulationduring disease development in gene knockout mice.II) Signal transduction of G-protein coupled receptors.III) Gene regulation of IgG Fc receptors and their targeting for theestablishment of new therapeutic strategies.

Selected Publications:Schiller C. et al. Eur J Immunol. 2000; 30:481-490.Baumann U. et al. J Immunol. 2000; 164:1065-1070.Baumann U. et al. J Immunol. 2001; 167:1022-1027.Chouchakova N. et al. J Immunol. 2001; 166:5193-5200.Heusohn F. et al. J Immunol. 2002; 168:2857-2864.Radeke HH. et al. J Biol Chem. 2002; 277:27535-27544.Shushakova N. et al. J Clin Invest. 2002; 110:1823-1830.Nieswandt B. et al. Int Immunol. 2003; 15:341-349.Godau J, et al. J Immunol. 2004; 173(5):3437-45Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Wingender G, et al. Immunology. 2006; 117(1):117-26.Kumar V, et al. J Clin Invest. 2006 Feb;116(2):512-20.

First name:J. Engelbert

Last name:Geßner

Acad. Title:Prof. Dr. rer.nat.Dr. hum.biol.habil.



Further information:www.mh-hannover.de/kliniken/immun

Department and function:Director, Molecular Biology

Education:1982 B.S. Eberhard-Karls-University, Tübingen,) 1983 M.S. Friedrich-Miescher-Laboratory (FML) of

the Max-Planck-Society, Tübingen1986 Ph.D. Max-Planck-Society, Tübingen1987 - 1989 Postdoc at the Mount Sinai Hospital Res.

Institute, Toronto, Canada

Positions:June 1989- July 1994 Head of an independent research group at

Max-Delbrück-Lab., Cologne, GermanyApril 1994 Habilitation: University of Cologne Aug. 1994 - July 1997 Associate Staff Scientist, The Jackson

Laboratory, Bar Harbor, MEAug. 1997 - June 1999 Staff Scientist , The Jackson Laboratorysince July 1999 Professor for Molecular Biology, MHH

Major research interests:The main research interest of the group lies on the analysis of the molecular mechanisms underlying developmental processes during mammalian embryogenesis. Development of the Notochord The notochord is a transient embryonic structure that serves as a signaling center that is essential for the dorsoventralpatterning of the spinal cord and somites. Various mutations in mice disturb the development or maintenance of the notochord. Identification and functional characterization of the genes affected by these mutations is the subject of several projects. Somitogenesis Somites form as the result of segmentation of the paraxial mesoderm. They give rise to the vertebrae, ribs, the epaxial and hypaxialmuscles and the dorsal dermis. Their formation lays the basis for the metameric arrangement of the vertebrae and of the spinal ganglia. The formation of segments as well as their subdivision into cranial and caudal compartments is the subject of our investigations. We analyse the role of Notch signalling in these processes as well as spontaneous mouse mutants in which somitogenesis is disrupted.

Selected Publications:Watabe-Rudolph M, Schlautmann N, Papaioannou VE, Gossler A. MOD 2002; 119:251-256Aulehla A, Wehrle C, Kemler R, Mallo M., Gossler A., Kanzler B, Herrmann BG. Dev. Cell 2003; 4: 395-406Serth K, Schuster-Gossler K, Cordes R, Gossler A.Genes Dev. 2003; 17(7):912-25Cordes R, Schuster-Gossler K, Serth K, Gossler A. Development. 2004; 131:1221-33Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21.Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, et al. Genes Dev. 2004; 18(14):1725-36Hofmann M, Schuster-Gossler K, Watabe-Rudolph M, Aulehla A, Herrmann BG, Gossler A. Genes Dev. 2004; 18(22):2712-7

First name:Achim

Last name:Gossler




Further information:http://www.mh-hannover.de/institute/molekularbiologie/

Department and function:Group Leader, Medical Microbiology

Education:1983 – 1990 Medical School in Würzburg, Bonn and Köln1991 – 1993 MD thesis

Positions:1994 – 1996 Postdoc, Tufts University, BostonFrom 1996 Research associate, Institute of Medical Microbiology,


Major research interests:-Virulence of enterohemorrhagic E. coli and pathogenicity of EHEC-infections-Microbe/host interactions in EHEC-disease-Development of diagnostic tools for detection of bacterial pathogens

Selected Publications:Gunzer F, Hennig-Pauka I, Waldmann KH, Sandhoff R, Gröne HJ, et al. Am.J.Clin.Pathol. 2002; 118:364-375.Gunzer F, Hennig-Pauka I, Waldmann KH, Mengel M. Methods Mol.Med. 2003;73:307-327.Pulz M, Matussek A, Monazahian M, Tittel A, Nikolic E, et al. J Clin Microbiol. 2003; 41(10):4671-5. Matussek A, Lauber J, Bergau A, Hansen W, Rohde M, et al. Blood. 2003; 102(4):1323-32Pulz M, Matussek A, Monazahian M, Tittel A, Nikolic E, Hartmann M, Bellin T, Buer J, Gunzer F. J Clin Microbiol. 2003; 41(10):4671Ma HW, Kumar B, Ditges U, Gunzer F, Buer J, Zeng AP. Nucleic Acids Res. 2004; 32(22):6643-9.Westendorf AM, Templin M, Geffers R, Deppenmeier S, Gruber AD, Probst-KepperM, Hansen W, Liblau RS, Gunzer F, Bruder D, Buer J. Gut. 2005; 54(1):60-9Ukena SN, Westendorf AM, Hansen W, Rohde M, Geffers R, Coldewey S, SuerbaumS, Buer J, Gunzer F. BMC Med Genet. 2005, 13;6:43.

First name:Florian

Last name:Gunzer

Acad. Title:MD (Dr. med.)



Further information:http://www.mh-hannover.de/institute/mikrobiologie/

Department and function:Head of Junior Research Group Immunodynamics, GBF

Education:1999 Diploma in Biochemistry, University of

Witten/Herdecke, Witten1999 PhD in Biology (Immunology), University of

Witten/Herdecke, Witten

Positions:2003-recent Junior Research Group Leader at the German Research

Centre for Biotechnology (GBF), Braunschweig

Major research interests:Analysis of cell migration in vitro and in vivoT cell activationImmunological defence against pathogens

Selected Publications:Gunzer, M., Kämpgen, E., Bröcker, E.-B., Zänker, K.S., Friedl, P. Adv. Exp. Med. Biol. 1997; 417: 97-103.Gunzer, M., Friedl, P., Niggemann, B., Bröcker, E.-B., Kämpgen, E., Zänker, K.S. J.Leukoc.Biol. 2000; 67: 622-629.Gunzer, M., Schäfer, A., Borgmann, S., Grabbe, S., Zänker, K.S., Bröcker, E.-B., Kämpgen, E., Friedl, P. Immunity 2000; 13: 323-332Gunzer, M., Weishaupt, C., Planelles, L., Grabbe, S. J Immunol Methods 2001; 258: 55-63Gunzer, M., Weishaupt C., Hillmer A., Basoglu Y., Friedl P., Dittmar K.E., Kolanus W., Varga G., Grabbe S. Blood 2004; 104:2801-2809.Gunzer M, Riemann H, Basoglu Y, Hillmer A, Weishaupt C, Balkow S, et al. Blood. 2005; 106(7):2424-32.Friedl P, den Boer AT, Gunzer M. Nat Rev Immunol. 2005 Jul;5(7):532-45.

First name:Matthias

Last name:Gunzer

Acad. Title:Dr.

Address:German Research Centre for BiotechnologyMascheroder Weg 1D-38124 Braunschweig


Further information:http://www.gbf.de/id

Department and function:Head Vaccine Research Group, Microbial Pathogenesis and Vaccine Research, Division of Microbiology, GBF

Education:1976-1981 Medicine, National University Rosario, Argentina1982-1986 Specialisation in Bacteriology, Rosario, Argentina 1988 MD, University of Genoa, Italy1989 Qualifying Medical Graduates Examination, School of

Medicine and Surgery, Genoa, Italy1993 PhD in Microbiology, University of Genoa, Italy2000 Habilitation Medical Microbiology, Hanover Medical

School

Positions:Since 1994 Head Vaccine Research, GBF, Braunschweig, Germany1991 - 1993 Laboratory of Microbial Pathogenesis, Univ. Genoa, Italy1989 - 1991 Division of Microbiology, GBF, Braunschweig, Germany1986 - 1989 Institute of Microbiology, Genoa, Italy1982 - 1986 National University of Rosario, Argentina1982 - 1986 Italian Hospital, Rosario, Argentina1982 - 1986 Children Hospital, Rosario, Argentina

Major research interests:Vaccinology, mucosal immunity, development of antigen delivery systems and adjuvants.

Selected Publications:Link C, Gavioli R, Ebensen T, Canella A, Reinhard E, Guzman CA Eur J Immunol. 2004; 34(3):899-907Ebensen T, Paukner S, Link C, Kudela P, de Domenico C, Lubitz W, Guzman CA Bacterial ghosts are an efficient delivery system for DNA vaccines. J Immunol. 2004 Jun 1;172(11):6858-65.Fey A, Eichler S, Flavier S, Christen R, et al. Appl Environ Microbiol. 2004; 70(6):3618-23.Borsutzky S, Cazac BB, Roes J, Guzman CA J Immunol. 2004; 173(5):3305-9. Rharbaoui F, Westendorf A, Link C, Felk S, et al. Infect Immun. 2004; 72:6978-86.Guzman CA, Feuerstein GZ. Curr Opin Biotechnol. 2004; 15(6):503-5Schulze K, Goldmann O, Toppel A, Medina E, Guzman CA. Vaccine. 2005; 23(11):1408-13.Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Guzman CA, Cebolla A, Beltrametti F, Staender LH, de Lorenzo V. FEBS Lett. 2005; 579(3):813-8.Borsutzky S, Kretschmer K, Becker PD, Muhlradt PF, Kirschning CJ, Weiss S, Guzman CA. J Immunol. 2005; 174(10):6308-13.Schulze K, Medina E, Guzman CA. Vaccine. 2006; 24(9):1446-50.Borsutzky S, Ebensen T, Link C, Becker PD, Fiorelli V, Cafaro A, Ensoli B, Guzman

CA. Vaccine. 2006; 24(12):2049-56.

First name:Carlos Alberto

Last name:Guzman

Acad. Title:MD, PhD

Address:GBFMascheroder Weg 138124-Braunschweig


Department and function: Director, Nephrology; Chairman, Department of Internal Medicine

Education:1972-1982 Chemistry, Art History, Medicine in

Tübingen, Berlin and Cardiff

Positions:1992-1996 Assistenzarzt FU Berlin1996-1999 Postdoctoral Fellowship Yale University1992-1997 Professor of Medicine, Franz-Volhard-Klinik

at the Max Delbrück Centre, Berlin1999 Professor of Medicine, MHH

Major research interests:I am interested in acute and chronic changes of the vasculature. I havestarted in analysing signal transduction pathways in vascular smooth muscle cells and gradually moved into endothelial cells. Additionally, I am interested in vascular development, circulating endothelialprogenitor cells and stem cells in the kidney.

Selected PublicationsFiebeler A, Park JK, Muller DN, Lindschau C, Mengel M, et al. Am J Kidney Dis. 2004 Feb;43(2):286-95Fiebeler A, Borgmann S, Woywodt A, Haller H, Haubitz M. Nephrol Dial Transplant. 2004; 19(4):969-7Mazak I, Fiebeler A, Muller DN, Park JK, et al. Circulation. 2004; 109(22):2792-800.Woywodt A, Goldberg C, Scheer J, Regelsberger H, Haller H, Haubitz M Ann Hematol. 2004; 83(8):491-4Haubitz M, Votsch K, Woywodt A, Nashan B, et al. Transplantation. 2004; 77(10):1517-21de Groot K, Bahlmann FH, Sowa J, Koenig J, et al. Kidney Int. 2004; 66(2):641-6Menne J, Park JK, Boehne M, Elger M, et al. Diabetes. 2004; 53(8):2101-9Bahlmann FH, Song R, Boehm SM, Mengel M, et al. Circulation. 2004; 110:1006-1Kielstein JT, Boger RH, Bode-Boger SM, Martens-Lobenhoffer J, et al. Clin Nephrol. 2004; 62(4):295-300Schwarz A, Mengel M, Gwinner W, Radermacher J, et al. Kidney Int. 2005; 67(1):341-8Fliser D, Wagner KK, Loos A, Tsikas D, Haller H. J Am Soc Nephrol. 2005; 16(4):1135-40.Schwarz A, Gwinner W, Hiss M, Radermacher J, Mengel M, Haller H. Am J Transplant. 2005; 5(8):1992-6Gwinner W, Menne J, Lonnemann G, Bahlmann F, Koch KM, Haller H. Int J ArtifOrgans. 2005 Dec;28(12):1224-7.Agrawal R, Marx A, Haller H. J Hypertens. 2006; 24(1):185-92

First name:Hermann

Last name:Haller




Further information:[email protected]

Department and function:Head, Gene Regulation and Differentiation And Division of Molecular Biotechnology, GBF

Education:1969-1974 University of Stuttgart-Hohenheim, Food technology1974-1977 PhD thesis at University of Konstanz, Biology

Positions:1978-1980 Post-Doc at MPI f. Molecular Genetics, Berlin and

DKFZ, Heidelberg1981- Research fellow, group leader, head of dept.,

head of division, GBF, Braunschweig

Major research interests:1. Signal transduction in the cytokine system (signalling molecules

and their impact on transcription, cellular and systemic consequences)

2. Biotechnology with mammalian cells (protein production, viral vectors, cellular vaccines)

Selected Publications:Unsinger J, Kröger A, Hauser H, Wirth D. Molecular Therapy 2001; 4: 484-489Meraro D, Gleit-Kielmanowicz M, Hauser H, Levi B-Z. J. Immunology 2002; 168:6224-6231Feng X, Guo Z, Nourbakhsh M, Hauser H, Ganster R, et al. Proc. Natl. Acad. Sci.USA 2002, 99: 14212-14217Kröger A, Dallügge A, Kirchhoff S., Hauser H. Oncogene 2003, 22:1045-1056Spitzer D, Dittmar KE, Rohde M, Hauser H, Wirth D. J Virol. 2003; 77(10):6070-5Koster M, Lykke-Andersen S, Elnakady YA, Gerth K, et al. Exp Cell Res. 2003;

286(2):321-31Unsinger J, Lindenmaier W, May T, Hauser H, Wirth D. Biochem Biophys Res

Commun. 2004; 319(3):879-87Niedick I, Froese N, Oumard A, Mueller PP, Nourbakhsh M, Hauser H, Koster M. J

Cell Sci. 2004; 117(Pt 16):3447-58Wirth D, Hauser H. Methods Mol Biol. 2004;267:467-76.May T, Hauser H, Wirth D. Nucleic Acids Res. 2004; 32(18):5529-38May T, Wirth D, Hauser H, Mueller PP. Biochem Biophys Res Commun. 2005;

327(3):734-41May T, Mueller PP, Weich H, Froese N, Deutsch U, Wirth D, Kroger A, Hauser H.J Biotechnol. 2005; 120(1):99-110.Froese N, Schwarzer M, Niedick I, Frischmann U, Koster M, Kroger A, Mueller PP,

Nourbakhsh M, Pasche B, Reimann J, Staeheli P, Hauser H. Mol Cell Biol. 2006; 26(1):293-302.

First name:Hansjörg

Last name:Hauser

Acad. Title:Dr. rer. nat

Address:GBFMascheroder Weg 138124 Braunschweig

Phone and e-mail:++49 [email protected]


Department and function:Clinical ImmunologyResearch Associate

Education:1990 MD, Hannover Medical School

Positions:1990-1992: Internship, Dept. of Immunology and Transfusion

Medicine, Hannover Medical School 1992-1995: Research Fellowship (German Research Council, DFG)

in the Laboratory of Immunobiology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, USA

1995-recent: Resident in Internal Medicine, Clinical Immunology, Hannover Medical School

Major research interests:Analysis of NK cell functions in HIV infectionPrognostic factors in HIV infectionChemokines and chemokine coreceptorsImpact of GBV-C coinfection on HIV progression

Selected Publications:Tillmann HL, Heiken H, Knapik-Botor A, et al. N Engl J Med. 2001; 345(10):715-24.Grosse V, Schulte A, Weber K, Mendila M, Jacobs R, Schmidt RE, Heiken H. AIDS 2002; 16(7):1075-7.Tillmann HL, Stoll M, Manns MP, Schmidt RE, Heiken H. AIDS. 2002; 16(5):808-9.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE. J Clin Immunol. 2004; 24(3):281-6. Jacobs R, Heiken H, Schmidt RE. Mol Immunol. 2005; 42(2):239-49.

First name:Hans

Last name:Heiken

Acad. Title:Dr. med.




Department and function:Group Leader, Molecular Cardiology (Cardiology and Angiology)

Education:1994 PhD in Biology (Genetics and Developmental Biology),

University of ZürichZürich, CH

Positions:1994-1996: Post Doc in the Department of Biology at the EMORY University in Atlanta (Georgia, USA)1997-2001: Post Doc in the Department of Cardiology and

Angiology of Hannover Medical School2001-recent: Group Leader in Molekular Cardiology in the

Department of Cardiology and Angiology

Major research interests:Analysis of mechanisms of stress-dependent signal transductionresponsible for the transition of compenatory hypertrophy to decompensated hypertrophy in the heart. Focus on the gp130-JAK/STAT signaling pathway and AP-1 transcription factors.Regulation and role of pro-angiogenic gene CCN1 in the pathophysiology of the heart.

Selected Publications:Hilfiker A., Hilfiker-Kleiner D., Pannuti A., Lucchesi J. C.. EMBO J. 1997; 16: 2054-2060

Hilfiker-Kleiner D, Hilfiker A, Schieffer B, Engel D, Mann DL, Wollert KC, DrexlerH Cardiovasc Res. 2002; 53(2):460-469.

Hilfiker A., Hilfiker-Kleiner D., Fuchs M., Kaminski K., Lichtenberg, A., RothkötterH., Schieffer B., and Drexler H. Circulation. 2002; 106(2):254-260

Podewski E.K., Hilfiker-Kleiner D., Hilfiker A., Morawitz H., Lichtenberg A., Wollert K.C. and Drexler H. Circulation. 2003Hilfiker-Kleiner D, Kaminski K, Kaminska A., Fuchs M., Klein G., Podewski E.,Kiian I., Wollert K.C., Hilfiker A., Drexler H. Circulation 2004; 109(18):2227-33Hilfiker-Kleiner D, Hilfiker A, Fuchs M, et al. Circ Res. 2004; 95(2):187-95.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22): 3493-500.Hilfiker-Kleiner D, Hilfiker A, Kaminski K, Schaefer A, Park JK, Michel K, Quint A, Yaniv M, Weitzman JB, Drexler H. Circulation. 2005; 112(10):1470-7.

First name:Denise

Last name:Hilfiker-Kleiner

Acad. Title:PhD



Further information:www.mh-hannover.de/cardiology

Department and function:Professor, Biochemistry (Physiological Chemistry)

Education:1980 Diploma in Biology, University of Hannover1985 Ph. D., Ludwig-Maximilians-University Munich1993 Habilitation in Immunology, Medical School Hannover

Positions:1985-1987: Postdoctoral fellow at the Weizmann Institute of

Science, Rehovot, Israel1987-2001: Group leader, Institute of Pharmacology, Medical

School Hannover2001-2003: GBF-BraunschweigSince 2003: Professor for Biochemistry of Cellular Signal

Transduction, Institute of Biochemistry/Physiological Chemistry, Medical School Hannover

Major research interests:Post-transcriptional control of gene expression in inflammation

- cis-acting RNA elements- regulatory RNA-binding proteins- signalling pathways affecting post-transcriptional mechanisms

Selected Publications:Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.-Y.A., Shyu A.-B., Müller M., Gaestel M., Resch K., Holtmann. H. EMBO J. 1999; 18:4969-4980.Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N., Cooper J.A., Resch K., Kracht M. Mol. Cell. Biol. 1999; 19:6742-6753.Bollig F., Winzen R., Kracht M., Ghebremedhin B., Ritter B., Wilhelm A., Resch K., Holtmann H. Eur. J. Biochem. 2002; 269:5830-5839.Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H. Biochem Biophys Res Commun. 2003;301(3):665-7Winzen R, Gowrishankar G, Bollig F, Redich N, Resch K, Holtmann H .Mol Cell Biol. 2004; 24(11):4835-47Gowrishankar G, Winzen R, Bollig F, Ghebremedhin B, Redich N, Ritter B, Resch K, Kracht M, Holtmann H. Biol Chem. 2005; 386(12):1287-93.

First name:Helmut

Last name:Holtmann




Further information:www.mh-hannover.de/institute/biochemie

Department and function:Institute for Transfusion Medicine, Group Leader Cell Therapy

Education:1990-97 Graduated in Medicine, University of Bochum1999 M.D., University of Bochum1998-99 Postgraduate training in Hematology and Oncology,

University of Cologne2002-05 Postgraduate training in Transfusion Medicine,

University of Düsseldorf and Hannover Medical School

Positions:1998-99 Resident, Internal Medicine, University of Cologne2000-02 Research Fellow, FHCRC, Seattle, USA2002-04 Physician, Cord Blood Bank, Institute for Transplantation

Diagnostics & Cell Therapies, University of Düsseldorf2004-recent Group leader, Institute for Transfusion Medicine,

Hannover Medical School, Hannover

Major research interests:Cell and Gene Therapy, Immunogenetics, Stem Cell Biology, Large Animal Studies, Stem Cell Transplantation

Selected Publications:Horn, P.A., DeLuca, D., Jindra, P., Blasczyk, R. 2006. Human Immunology, in pressEiz-Vesper, B., Horn, P. A., et al. Transfusion 2006. in pressHorn, P.A., Blasczyk, R. Tissue Antigens 2005. 66, 56-57Horn, P.A., Mansmann V., Blasczyk, R. Tissue Antigens 2005. 66, 335-337Kiem, H.P., et al. Molecular Therapy 2004 9, 389-395Horn, P.A., K.A. Keyser, L.J. Peterson, T. Neff, et al. Blood 2004. 103: 3710-3716Horn, P.A., Morris, J.C., Neff, T., Kiem, H.P. Molecular Therapy 2004. 10, 417-431Neff, T.*, P.A. Horn*, et al. Journal of Clinical Investigation 2003. 112: 1581-1588Horn, P.A., B.M. Thomasson, B.L. Wood, et al. Blood 2003. 102: 4329-4335Storek, J., T. Gillespy III, H. Lu, A. Joseph, et al. Blood 2003. 101: 4209-4218Horn, P.A., J. Morris, A. Bukovsky, et al. Gene Therapy 2002. 9: 1464-1471Neff, T., P.A. Horn, V.E. Valli, A.M. Gown, et al. Blood 2002. 100: 2026-2031Horn, P.A.*, M.S. Topp*, J.C. Morris, R.S. Riddell, et al. Blood 2002. 100: 3960-7

First name:Peter A.

Last name:Horn

Acad. Title:Dr. med.



Further information:www.mh-hannover.de/institute/transfusion/transfusionsmedizin/

Department and function: Group Leader, Clinical Immunology

Education:1981-1986 Biology in Hannover

Positions:1987-recent Scientist in the Division of Clinical Immunology, MHH1992 PhD in Biology, MHH2003 Habilitation in Immunology, MHH

Major research interests:Analysis of Natural Killer (NK) cell subpopulations. Our particularinterest is focused on NK cells with weak cytoxic capacity that aresupposed to play an important role in immune regulation.

Selected PublicationsJacobs R, Hintzen G., Kemper A., Beul K., et al. Eur J Immunol 2001; 31: 3121-3126.Jacobs R., Pawlak C. R., Mikeska E., Meyer-Olson D., et al.. Rheumatol 2001; 40: 868-875.Kittner J. M., Jacobs R., Pawlak C. R., Heijnen C. J., Schedlowski M., Schmidt R. E.. Rheumatol 2002; 41: 1031-1039.Straub R. H., Kittner J. M., Heijnen C. J., Schedlowski M., Schmidt R. E., Jacobs R. J Rheumatol 2002; 29: 1659-1664.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE J Clin Immunol. 2004; 24(3):281-6Jacobs R, Heiken H, Schmidt RE Mol Immunol. 2005; 42(2):239-49

First name:Roland

Last name:Jacobs

Acad. Title:PD Dr.




Department and function:Assistant and research group leader department gastroenterology, hepatology, endocrinology

Education:1996 Master in medicine, University of Hamburg1997 MD, Dept. Pharmacology, Friedrich-Alexander

University, Erlangen

Positions:1996-1999: Research fellow and assistant Dept. Gastroenterology,

MHH, Hannover1998: Research Fellow, German Primate Center Goettingen1999-2003: Postdoctoral fellowship dept. cancer immunology and

AIDS, Dana Farber Cancer Institue, Harvard MedicalSchool, Boston

2003-recent: Assistant and research group leader departmentGastroenterology, Hepatology, Endocrinology

Major research interests:Mechanisms and regulation of immune tolerance in autoimmunity, alloimmunity and chronic infection

Selected Publications:Jaeckel E, Heringlake S, Berger D, Brabant G, Hunsmann G, Manns MP. Diabetes 1999; 48(1):209-14. Jaeckel E, Cornberg M, Santantonio T, Mayer J, et al. New England Journal of Medicine 2001; 345:1452-1457.Jaeckel E, Klein L, Martin-Orozco N, von Boehmer H. J Exp Med 2003; 197: 1635-1644.Wiegand J, Jackel E, Cornberg M, Hinrichsen H, et al. Hepatology 2004; 40:98-107.Jaeckel E, El-Armouche A, Boheler KR, Boknik P, et al. Biochem Biophys Res Comm 2004; 318: 219-226.Jaeckel E, Lipes MA, von Boehmer H. Nat Immunol 2004; 5: 1038-1035.Jaeckel E, von Boehmer H, Manns MP Diabetes 2005; 54: 306-310.Jaeckel E, Kretschmer K, Apostolou I, von Boehmer H. Semin Immunol. 2006; 18(2):89-92

First name:Elmar

Last name:Jaeckel

Acad. Title:MD

Address:OE6819TPFZ, K11/01-1450


Further information:www.mh-hannover.de/kliniken/gastro/gastro.htm

Department and function:Group leader (Institute of Medical Microbiology and Hospital Epidem.)

Education:1996 PhD in Biology (Microbiology/Biochemistry/Cell

Biology), Ruhr-University Bochum, Germany

2003 Habilitation in Medical Microbiology, University of Würzburg, Germany

Positions:1998-1999: Junior Research Group Leader, Dept. Medical

Microbiology, Ruhr-University Bochum, Germany

1999-2000: Post-Doctoral Research, Institute for Cellular Pathology, Université Catholique de Louvain, Bruxelles/Brussel, Belgium

2000-2004: Junior Research Group Leader, Institute for Hygiene and Microbiology, University of Würzburg, Germany

from 2004: Research Group Leader “Cellular Microbiology”Institute for Medical Microbiology and Hospital Epidem. at Hannover Medical School

Major research interests:Characterization of virulence mechanisms of pathogenic bacteriaBacterial sensing, signal transduction and gene regulationBacterial motility and secretion processesInfluence of bacteria on cellular signaling and immune responses in health (commensals) and disease (pathogens) in the gastrointestinal tract

Selected Publications:Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., et al. Proc. Natl. Acad. Sci. U.S.A. 2003; 100:7901-7906.Lee S. K., Stack A., Katzowitsch E., Aizawa S. I., Suerbaum S., Josenhans C. Microbes Infect. 2003; 5:1345-1356.Schreiber S., Stüben M., Groll C., Scheid P., et al. Natl. Acad. Sci. 2004; 101: 5024-5029.Niehus E., Gressmann H., Ye F., Schlapbach R., et al. Mol. Microbiol. 2004; 52: 947-961. Schmausser B., Josenhans C., Endrich S., Suerbaum S., et al. Infect. Immun. 2004; 72: 6773-6779.Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Garten D, Scheid P, et al. Infect Immun. 2005; 73(3):1584-9Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Scheid P, Gatermann S, Josenhans C, Suerbaum S. Arch Microbiol. 2006;184(5):335-40.

First name:Christine

Last name:Josenhans

Acad. Title:P.D. Dr. rer. nat. (Ph.D.)



Further information:www.mh-hannover.de/institute/mikrobiologie/

Department and function: Director, Toxicology

Education:1976-1988 Pharmacy in Münster

Medicine at Free University Berlin

Positions:1989-1995 Postdoc positions in Pharmacology at the Universities

of Giessen, Essen, Homburg/Saar1997 Post Orange Fellowship of INSERM in Nice, France1995-2000 Assistant Professor at the University of Freiburg2000 Professor of Toxicology, MHH

Major research interests:The molecular and cellular mode of action of bacterial proteintoxins and the functional consequences on the signal transductionof the target cells.

Selected Publications

Vetter, IR, Hofmann, F, Wohlgemut, S, Herrmann, C, Just, I. J. Mol. Biol. 2000; 301:1091-1095 Wilde, C, Chhatwal, GS, Schmalzing, G, Aktories, K, Just, I. J. Biol. Chem 2001; 276:9536-9542Wilde, C, Barth, H, Sehr, P, Han, L, Schmidt, M, Just, I, Aktories, K J. Biol. Chem. 2002; 277:14771-14776 Gerhard, R, John, H, Aktories, K, Just, I Mol. Pharmacol. 2003; 63:1349-1355Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just, I. J. Biol: Chem. 2003; 278: 28523-28527Ahnert-Hilger G, Höltje M, Große G, Pickert G, Mucke C, Nixdorf-Bergweiler B, Boquet P, Hofmann F, Just I. J. Neurochem. 2004, 90(1):9-18.Gerhard R, Tatge H, Genth H, Thum T, Borlak J, Fritz G, Just I J Biol Chem. 2005; 280(2):1499-1505Just I, Gerhard R. Rev Physiol Biochem Pharmacol. 2004; 152:23-47Gerhard R, Tatge H, Genth H, Thum T, Borlak J, Fritz G, Just I. J Biol Chem. 2005; 280(2):1499-505Gerhard R, Burger S, Tatge H, Genth H, Just I, Hofmann F. Microb Pathog. 2005; 38(2-3):77-83.

First name:Ingo

Last name:Just

Acad. title:Prof. Dr.



Further information:http://www.mh-hannover.de/

institute/toxikologie/

Department and function:Professor, Molecular Biology of Vertebrates

Education:1983-1989 University of Tübingen, Biochemistry1987-1988 Queen Mary College, London, Biochemistry1989-1990 Diploma thesis, MPI Tübingen1990-1993 PhD thesis, MPI Tübingen

Positions:1993-1994 Postdoc, MPI Tübingen1994-1996 Postdoc, Harvard University1997-2001 Group leader, MPI FreiburgSince 2001 C3 Professor, MHH

Major research interests:Genetic control of vertebrate (mouse) development:- Organogenesis (organs of mesodermal origin like kidneys, skeleton,

muscles, heart)- Function of Wnt and Tbx genes in development

Selected Publications:Kispert A, Vainio S, McMahon AP. Development 1998; 125: 4225-4234Herrmann BG, Koschorz B, Wertz K, McLoughlin KJ, Kispert A. Nature 1999; 402: 141-146Leitges M, Neidhardt L, Haenig B, Herrmann BG, Kispert A. Development 2000; 127: 2259-2267Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A. Cytogenet Genome Res. 2002; 98(4):274-7Moeller C, Swindell EC, Kispert A, Eichele G. Development. 2003; 130(21):5103-11. Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21Haenig B, Kispert A . Dev Genes Evol. 2004; 214(8):407-11.Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A. Mech Dev. 2005; 122(2):131-44Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A. Development. 2005 Jun;132(12):2697-707.Airik R, Bussen M, Singh MK, Petry M, Kispert A. J Clin Invest. 2006;116(3):663-74.

First name:Andreas

Last name:Kispert




Further information:http://www.ifm-mhh.de.vu/

Department and function:Professor; Pediatric Hematology/Oncology

Education:1983-1990 Medical School (University Ulm, Munich)1992 Magister Artium, Philosophy2000 Doctorat Immunology (Institut Pasteur, Paris)

Positions:1990 Residency in Pediatrics, University Munich1991-1994 Residency and Research Associate Hôpital Necker

Enfants Malades, Paris1994-1995 Residency in Pediatrics, University Freiburg1995-1998 Clinical and Research Fellow

Children‘s Hospital, Harvard Medical School Boston1998-2000 Instructor in Pediatrics and Research Associate, Howard

Hughes Medical Instit., Harvard Medical School, Boston2000- Hannover Medical School

Major research interests:Gene Therapy, Tumor Immunology, Stem Cell Biology

Selected Publications:Klein C, Bueler H, Mulligan RC. J Exp Med 2000; 191: 1699-1708Dahl AM, Klein C, Andres PG, London CA, Lodge MP, et al.. J Exp Med 2000,191:2031-2038Snapper SB, Takeshima F, Rosen FS, Antón I, Thomas S, et al. Nat Cell Biol 2001;3:897-904Robert C, Klein C, Cheng G, Kogan A, Mulligan RC, et al. Gene Therapy 2003; 10(17):1479-86Klein C, Nguyen D, Liu CH, Mizoguchi E, Bhan AK, Rosen FS, et al. Blood 2003; 101(6):2159-66Klein C, Baum C Hematol J. 2004;5(2):103-11Cloppenborg T, Stanulla M, Zimmermann M, Schrappe M, Welte K, Klein C.Leukemia. 2005; 19(1):44-8.Rathinam C, Geffers R, Yucel R, Buer J, Welte K, Moroy T, Klein C. Immunity. 2005; 22(6):717-28.Maecker B, Mougiakakos D, Zimmermann M, Behrens M, Hollander S, Schrauder A, Schrappe M, Welte K, Klein C. Leukemia. 2006 Feb 23Rathinam C, Sauer M, Ghosh A, Rudolph C, Hegazy A, Schlegelberger B, Welte K, Klein C. Leukemia. 2006 Mar 2

First name:Christoph

Last name:Klein

Acad. Title:Prof. Dr., PhD


Phone and e-mail:+49-511-532 [email protected]

Further information:www.mh-hannover.de/Kliniken/paed_haemonko/Klinik.htm

Department and function:Assistant Medical Director, Medical Microbiology

Education:1980 - 86 Study of Medicine at the Johannes-Gutenberg University

Mainz1988 - 91 Experimental training in Molecular Biology and Cell

Biology at the Baylor College of Medicine, Department ofCell Biology, Houston, Texas, Medical Center

2000 Consultant with board certification in Med. Microbiol.

Positions:1987 - 88 Research Assistent in the Department of Medical

Microbiology, Johannes-Gutenberg University, Mainz1991 -2000 Research Assistant and, from 2001 on, Assistant Medical

Director at the Department of Medical Microbiology, MHH

Major research interests:Basic research on …1. Chlamydia: Bacteria–host-cell interaction, regulated host-cell genes, mechanisms and signalling pathways2. Complement: Anaphylatoxic peptides C3a, C5a and their G-proteincoupled receptors as part of the innate immunity, receptor regulation on various levels including gene-regulation and interaction with cytokines

Selected Publications:Settmacher B, Rheinheimer C, Hamacher H, Ames RS, et al. Eur J Immunol. 2003; 33(4):920-7Hess S, Peters J, Bartling G, Rheinheimer C, et al. Cell Microbiol. 2003; 5(11):785-95Otto M, Hawlisch H, Monk PN, Muller M, et al. J Biol Chem. 2004; 279(1):142-51Godau J, Heller T, Hawlisch H, Trappe M, et al. J Immunol. 2004; 173(5):3437-45.Fischer SF, Vier J, Kirschnek S, Klos A, et al. J Exp Med. 2004; 200(7):905-16.Peters J, Hess S, Endlich K, Thalmann J, Holzberg D, Kracht M, Schaefer M, Bartling G, Klos A. Cell Microbiol. 2005; 7(8):1099-108Schaefer M, Konrad S, Thalmann J, Rheinheimer C, Johswich K, Sohns B, Klos A..J Biol Chem. 2005; 280(51):42113-23

First name:Andreas

Last name:Klos




Further information:www.mh-hannover.de/institute/mikrobiologie/

Department and function:Group Leader, Biochemistry (Physiological Chemistry)

Education: 1978-1985 Medical School, Charkov, Ukraine1987-1991 PhD thesis

Positions:Research Assistent

Major research interests:MAPK cascades activated by stress or cytokinesSignalling events that are triggered by p38 activity,and analyse how these events contribute to specific gene expression and cellular responses.

Selected Publications:Kotlyarov A., Neininger C., Schubert R., Eckert C., Birchmeier H-D, et al. Nature Cell Biol. 1999; 1: 94-97.Kotlyarov A, Gaestel M. Biochem. Soc. Trans. 2002; 30: 959-963.Kotlyarov A, Yannoni Y, Fritz S, Laaß K, Telliez J-B, et al. Mol. Cell. Biol. 2002; 22: 4827–4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21):7732-41.Wu Y, Hannigan MO, Kotlyarov A, Gaestel M, Wu D, Huang CK. Biochem Biophys Res Commun. 2004; 316(3):666-7Schumacher S, Laass K, Kant S, Shi Y, et al. EMBO J. 2004; 23(24):4770-9.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006 Mar;26(6):2399-407

First name:Alexey

Last name:Kotlyarov

Acad. Title:MD



Further information:www.mh-hannover.de/ institute/biochemie/

Department and function:Director, Institute of Pathology

Education:1976-1982 Study of Medicine, University of Kiel1985 Doctoral thesis, University of Kiel1991 Habilitation , University of Kiel

Positions:1984 - 1993: Institute of Pathology, University of Kiel; senior

registrar since 19911993 - 1998: Professor and Deputy Director Institute of Pathology

University of Würzburgsince 1998: Professor and Head of the Department of Pathology,

Medizinische Hochschule Hannover

Major research interests:Molecular pathology of breast cancer and leukemiasDifferentiation and regeneration of normal tissues

Selected Publications:Lehmann U, Langer F, Feist H, Glockner S, Hasemeier B, Kreipe H. Am J Pathol. 2002; 160(2):605-12.Lehmann U, Celikkaya G, Hasemeier B, Langer F, Kreipe H. Cancer Res. 2002; 62(22):6634-8.Tammen H, Kreipe H, Hess R, Kellmann M, Lehmann U, Pich A, Lamping N, Schulz-Knappe P, Zucht HD, Lilischkis R. Breast Cancer Res Treat. 2003; 79(1):83-93.Serinsoz E, Neusch M, Busche G, Wasielewski R, Kreipe H, Bock O. Br J Haematol. 2004; 126(3):313-9.Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Am J Pathol. 2004;165(6):2079-85.Bock O, Loch G, Schade U, Büsche G, von Wasielewski R, Wiese B, Kreipe H. Br J Haematol. 2005; 130:76-82Lehmann U, Versmold A, Kreipe H. Methods Mol Biol. 2005;293:113-23.

First name:Hans H.

Last name:Kreipe




Further information:www.mh-hannover.de/institute/pathologie

Department and function:Head of Immunology, Allergology and Clinical Inhalation Research, ITEM

Education:1981-89 Medicine in Hannover, Göttingen and Hartford (USA)1998-2000 Degree in Internal Medicine, Respiratory Medicine,

Allergology and Intensive Care Medicine, Hannover Medical School (MHH)

1999 Habilitation in Internal Medicine (MHH)

Positions:1989-93 and1995-2000: Assistenzarzt Medical School Hannover (MHH)1993-95: Postdoctoral Fellowship University Bochum and

University Southampton (German Research CouncilScholarship)

since 2000: Professor of Immunology, Allergology and Clinical Inhalation Research, MHHand Head of Department Immunology, Allergology and Clinical Inhalation Research, Fraunhofer ITEM

Major research interests:Pathophysiology and therapeutic interventions of airway diseases, in particular asthma. Preclinical and clinical research.

Selected Publications:Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, et al. J Exp Med 2003; 198; 455-67.Erpenbeck VJ, Hagenberg A, Dulkys J, Elsner J, Krentel H, et al. Am J Respir Crit Care Med 2004; 169; 578-586.Hohlfeld JM, Schmiedl A, VJ Erpenbeck, Venge P, Krug N. J Allergy Clin Immunol 2004; 113: 496-502.Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A. J Immunol. 2004; 172:6080-6.Schaumann F, Borm PJ, Herbrich A, Knoch J, et al. Am J Respir Crit Care Med. 2004; 170(8):898-903.Erpenbeck VJ, Malherbe DC, Sommer S, Schmiedl A, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Dec 10Baelder R, Fuchs B, Bautsch W, Zwirner J, et al. J Immunol. 2005; 174(2):783-9.Krug N, Hohlfeld JM, Geldmacher H, Larbig M, Heermann R, Lavallee N, Nguyen DT, Petzold U, Hermann R. Allergy. 2005 Mar;60(3):354-9.Erpenbeck VJ, Hagenberg A, Krentel H, Discher M, Braun A, Hohlfeld JM, Krug N.Int Arch Allergy Immunol. 2006 Feb 22;139(4):306-316

First name:Norbert

Last name:Krug


Address:Fraunhofer Institute forToxicology and Experimental MedicineNikolai-Fuchs-Str. 130625 Hannover


Further information:www.item.fraunhofer.de

Department and f unction:Group Leader and Head of the Laboratory of MolecularDiagnostics; Pathology

Education:1986-1992 University of Hannover, Biochemistry1992-1996 PhD, Molecular Biology

Positions:1996-1998 Head Laboratory of Molecular Diagnostics

Institute of Pathology, Bielefeldsince 1999 Research Group Leader and Head of the

Laboratory of Molecular Diagnostics,Institute of Pathology, Hannover Medical School

Major research interests:Epigenetics of malignant neoplasiaTumor evolutionMolecular diagnosis of neoplasiaMain focus on breast cancer and hematological neoplasia in humans

Selected Publications:Lehmann U, Celikkaya G, Hasemeier B, Länger F, Kreipe H. Cancer Res 2002;62: 6634-6638.Kleeberger W, Versmold A, Rothamel T, Glockner S, Bredt M, et al. Am J Pathol. 2003; 162(5):1487-94Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U.Leukemia. 2003; 17(5):910-8. Tessema M, Lehmann U, Kreipe H. Cell cycle and no end. Virchows Arch. 2004 Apr;444(4):313-23.Lehmann U, Brakensiek K, Kreipe H. Ann Hematol. 2004; 83(3):137-52Lehmann U, Kreipe H. Methods Mol Biol. 2004; 287:207-18.Langer F, Stickel J, Tessema M, Kreipe H, Lehmann U. Leuk Res. 2004; 28(10):1081-3.Brakensiek K, Langer F, Kreipe H, Lehmann U. Blood. 2004; 104(5):1586-7Tessema M, Langer F, Bock O, Seltsam A, Metzig K, Hasemeier B, Kreipe H, Lehmann U. Int J Oncol. 2005; 26(2):499-507.Langer F, Dingemann J, Kreipe H, Lehmann U. Leuk Res. 2005; 29(3):325-9.Lehmann U, Berg-Ribbe I, Wingen LU, Brakensiek K, Becker T, KlempnauerJ, et al. Clin Cancer Res. 2005; 11(10):3654-60.Brakensiek K, Langer F, Kreipe H, Lehmann U. Leuk Res. 2005; 29:1357-60.Brakensiek K, Langer F, Schlegelberger B, Kreipe H, Lehmann U. Br J Haematol. 2005; 130(2):209-17.Lehmann U, Kreipe H. Methods Mol Med. 2006;120:65-75.

First name:Ulrich

Last name:Lehmann

Acad. Title:PD Dr. rer. nat.



Further information:www.mh-hannover.de/ institute/pathologie/

Department and function:Division of Microbiology, Head of the Junior Research Group Infection Genetics, GBF - German Research Centre for Biotechnology

Education:1997 PhD in Biology (Genetics), University of Bielefeld

Positions:1997-2000: Postdoctoral Research Fellow at the University of

Pennsylvania, Medical School, Philadelphia, USA2000-2001: Senior Research Scientist at the Institute of Mammalian

Genetics, National Research Centre for Health andEnvironment (GSF), in Munich

2001-recent: Junior Research Group Leader at the German Research Centre for Biotechnology (GBF).

Major research interests:Host-pathogen interactions, Mouse infection models, Macrophage functions during infections, Clearance of apoptotic cells, Infection Genetics.

Selected Publications:Hough, R.B., Lengeling, A., Bedian, V., Bucan, M. PNAS 1998; 95: 13800-13805.Lengeling, A., Wiltshire, T., Otmani, C., Bucan, M. Genome Res.1999; 9: 732-738.Lengeling, A., Pfeffer, K. and Balling, R. Mamm. Genome 2001; 12: 261-271.Schneider, J.E., Böse, J., Bamforth, S.D., Gruber, A.D., Broadbent, C., Clarke, K.,Neubauer, S., Lengeling, Bhattacharya, S. BMC Dev. Biol. 2004; 4: 16.Böse, J., Gruber, A.D., Helming, L., Schiebe, S., Wegener, I., Hafner, M., Beales, M., Köntgen, F., Lengeling, A. Journal of Biology 2004; 3, 15.Helming L, Bose J, Ehrchen J, Schiebe S, Frahm T, Geffers R, Probst-Kepper M, Balling R, Lengeling A. Blood. 2005; 106(13):4351-8Medina E, Lengeling A. Brief Funct Genomic Proteomic. 2005; 4(3):248-57.

First name:Andreas

Last name:Lengeling


Address:Mascheroder Weg 138124 Braunschweig



Department and function:Project leader, Experimental Cell Therapy,Dept. Hematology, Hemostaseology and Oncology

Education:1993 Master of Medicine (equivalent to MD)

Tongji Medical School, Wuhan, PR. China1998 MD, University of Hamburg, Hamburg

Positions:1993-1995 Clinical and Research fellow, Tongji Medical School1995-1996 Clinical fellow, Clinic of Dr. Kleeberg (HOPA,

Hamburg)1996-1998 Research fellow, Center for Bone Marrow

Transplantation, University Hospital Eppendorf,Hamburg

1999-2002 Faculty member and Deputy Director Department of HematologySun Yat-Sen Memorial HospitalSun Yat-Sen University, Guangzhou, PR. China

2000-2002 Postdoctoral fellowDepartment of Cell & Virus GeneticsHeinrich-Pette-Institute, University of Hamburg

2001-present Staff scientist, project leaderHannover Medical School

Major research interests:1) Leukemogenesis of receptor tyrosine kinases;2) Stem cell biology; 3) Gene therapy

Selected Publications:Li Z et al., Science 2002;296:497Li Z et al., Leukemia 2002;16:1655-63Schiedlmeier B et al., Blood 2003;101:1759-68Li Z et al., Experimental Hematology 2003; 31:1206-1214Baum C et al., Blood 2003;101:2099-2113Baum C et al., Molecular Therapy 2004;9:5-13Modlich U et al., Blood 2005 Jun 1;105(11):4235-46Kustikova O, et al. Science. 2005; 308(5725):1171-4.

First name:Zhixiong

Last name:Li

Acad. Title:MD



Department and functionGroup Leader, Cell Biology

Education:1982-1987 Biology, Technical University of Munich1988-1992 PhD Thesis, MPI for Biochemistry, Martinsried

Positions:1992-1997 Postdoc at Washington University, St. Louis, MO, USA1997-2000 Assistant in the Department of Immunobiology,

University of Bonnsince 2000 Assistant in the Department of Cell Biology

Major research interests:Antigen processing and presentation; intracellular sorting of MHC II molecules, antigens and cofactors for antigen processing; lipid rafts and their function in MHC II biology; roles of intestinal epithelial cells in mucosal immunity

Selected Publications:Lindner R., Unanue E. EMBO J. 1996; 15: 6910-6920.Lindner R. Electrophoresis 2001; 22: 386-393.Lindner R. Traffic 2002; 3: 133-146.Karacsonyi C, Knorr R, Fulbier A, Lindner R J Biol Chem. 2004; 279(33):34818-2Karacsonyi C, Bedke T, Hinrichsen N, Schwinzer R, Lindner R. J Leukoc Biol. 2005; 78(5):1097-105.

First name:

Robert

Last name:Lindner



Phone and e-mail:++49- 511- 532-2918

[email protected]

Further information:www.mh-hannover.de/Institute/Zellbiologie/

Department and function:Group Leader, Gastroenterology, Hepatology and Endocrinologyand Molecular Biology

Education:6/96 MD1/98-12/00 Post Doc Fred Hutchinson Cancer Center, Seattle WA;

USA

Positions:since 1/96 Dept. of Gastroenterology, MHHsince 2/01 Dept.of Gastroenterology and Institute for Molecular

Biology

Major research interests:My scientific interest concentrates on the understanding of themammalian cell cycle, specifically on the control of cyclin dependentkinases. Our research tries to elucidate the molecular regulation of cyclin kinase inhibitors by proteolytic mechanisnms. We are usingbiochemistry and mouse models as our main tools.

Selected Publication:Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts J. Nature2001; 413: 323-27.Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, et al. Proc Natl Acad SciUSA 2003; 100(13):7797-802.Kossatz U, Dietrich N, Zender L, Buer J, Manns MP, Malek NP. Genes Dev. 2004; 18(21):2602-7

First name:Nisar Peter

Last name:Malek

Acad. Title:Dr.med.



Further information:http://www.mh-hannover.de/ kliniken/gastro/gastro.htm

Department and function:Director, Biophysical Chemistry

Education:1986 PhD in Biochemistry, Heidelberg University1999 Venia Legendi for Biochemistry and Biophysics,

Heidelberg University

Positions:1986 Research Associate, University of Michigan, USA1987-1990 Postdoctoral Fellow, Stanford University, USA1990-1996: Group Leader, National Institute for Medical

Research, London, UK1996-2002: Senior Group Leader, Max-Planck-Institute for

Medical Research, Heidelberg2002-: Professor of Biophysical Chemistry, MHH

Major research interests:Molecular motorsRegulation of dynamic changes in the cytoskeleton associated with cellmovements and cytokinesisG-protein mediated processes

Selected Publications:Knetsch, M.L.W., Schäfers, N., Horstmann, H., Manstein, D. J. EMBO J 2001, 20:1620-1629.Klockow, B., Tichelaar, W., Madden, D., Niemann, H.H., Akiba, T., Hirose, K., anstein, D.J. EMBO J 2002, 21: 240-250.Krylyshkina, O., Manstein, D.J. et al. J. Cell Biol. 2003, 161: 853-859.Reubold, T.F., Eschenburg, S., Becker, A., Kull, F.J., Manstein, D.J. Nature Struct.Biol 2003, 10: 826-830.Tsiavaliaris G, Fujita-Becker S, Manstein DJ. Nature. 2004; 427(6974):558-61.Fujita-Becker S, Durrwang U, Erent M, Clark RJ, Geeves MA, Manstein DJ. J Biol

Chem. 2005; 280(7):6064-71Reubold TF, Eschenburg S, Becker A, Leonard M, Schmid SL, Vallee RB, Kull FJ,

Manstein DJ. Proc Natl Acad Sci U S A. 2005; 102(37):13093-8.Durrwang U, Fujita-Becker S, Erent M, Kull FJ, Tsiavaliaris G, Geeves MA,

Manstein DJ. J Cell Sci. 2006; 119(Pt 3):550-8.

First name:Dietmar

Last name:Manstein




Further information:http://www.bpc.mh-hannover.de/

Department and function:Professor, Senior Research Group leader

Education:1961 Dipl. chem.., University of Cologne, Germany1964 Ph.D. (Dr.rer.nat.), University of Cologne, Germany1971 Dr.rer.nat. habil., Venia legendi, University of Freiburg

i.Br. Germany Faculty of Biology

Positions:1965-67 Research Associate, Salk Institute for Biological

Studies, La Jolla, CA, USA (Fulbright Travel Scholar)1968-69 Postdoctoral Fellow, Max Planck Institute for Molecular

Genetrics, Beriln, Germany1970 Senior Research Assistant, Max Planck Institute for

Molecular Genetrics, Berlin, Germany1970 Visiting Scientist, Weizmann Institute, Rehovot, Israel1970-71 Visiting Scientist, Department of Genetics, Stanford

University Medical School, Stanford, CA1970-1980 Permanent Member, Basel Institute for Immunology,

Basel, Switzerland1980-2001 Director, Basel Institute for Immunology, Basel,

Switzerland2003- Senior Research Group Leader, Max Planck Institute for

Infection Biology, Berlin, Germany

Major research interests:The senior group will continue to work on some projects which were developed at the Basel Institute for Immunology and which have focused on the development of cells of the innate and adaptive from stem cells and early progenitors and which have studied the development of B-lymphocytes in greater details.

Selected Publications:Shimizu T, Mundt C, Licence S, Melchers F, Martensson IL. J Immunol. 2002; 168, 6286-93.Rolink AG, Schaniel C, Melchers F. Immunol Rev. 2002; 187, 87-95.Hoffmann R, Bruno L, Seidl T, Rolink AG, Melchers F. J Immunol. 2003; 170, 1339-53.Ohnishi K, Melchers F. Nat Immunol. 2003; 4, 849-56.Melchers F. Nat Rev Immunol. 2005; 5, 578-84.

First name:Fritz

Last name:Melchers


Address:Max Planck Institute for Infection BiologyCampus Charité MitteSchumannstr. 21/2210117 Berlin, Germany


Further information:http://www.mpiib-berlin.mpg.de/

Department and function:Associate Professor, Virology

Education:1990 PhD in Biology (Genetics), Eberhard Karls-University

Tübingen2002 Habilitation in Experimental Virology,

Ludwig Maximilians-University München

Positions:1991-1994: Postdoc at the Department of Virology, University

of Ulm and Department of Haematology and Oncology, University of Freiburg

1995-2001: Research Group Leader at the Department of Virology, University of Heidelberg and at the Max von Pettenkofer-InstituteLudwig-Maximilians-University München

2001-2004: Leader of the Virus-Cell-Interaction Unit at the Medical Faculty, University of Halle-Wittenberg

since 2005: Professor of Molecular Virology, Hannover Medical School

Major research interests:Analysis of viral proteins involved in the interaction of herpesviruseswith their host cellsImmunomodulation by herpesvirusesDevelopment of viral vectors for gene transfer, vaccination and tumortherapy

Selected Publications:Messerle M., Crnkovic I., Ziegler H., Hammerschmidt W., Koszinowski U.H. Proc. Natl. Acad. Sci. 1997; 94:14759-14763.Borst E., Hahn G., Koszinowski U.H., Messerle M. J. Virol. 1999; 73:8320-8329. Borst E., Mathys S., Wagner M., Muranyi W., Messerle, M. J. Virol. 2001; 75:1450-1458.Mathys S., Schroeder T., Ellwart J., Koszinowski U.H., Messerle M., Just U. J. Inf. Dis. 2003; 187:988-999.Borst E., Messerle M. Hum. Gene Ther. 2003; 14:959-970. Loewendorf A., Krueger C., Borst E., Wagner M., Just U., Messerle M. J. Virol. 2004; 78:13062-13071.Borst E., Messerle, M. J. Virol. 2005; 79(6):3615-26.

First name:Martin

Last name:Messerle




Further information:www.mh-hannover.de/institute/virologie/home.html

Department and function:Group Leader Molecular Genetic Diagnostics

Education:1988-1994 Study of marine biology, University of Kiel

Main focus: marine pathology1994 Thesis at Robert Koch Institut Berlin (AIDS Zentrum)1999 PhD in cell biology, University of Kiel

Positions:1994-2000: Group Leader, Stem Cell Transplantation Unit of the II.

Medical Clinic, University of Kiel2001 Head of Molecular Genetic Diagnostics, Institute of Cell

and Molecular Pathology, Hannover Medical School

Major research interests:- Modification of steroid resistance in childhood leukemia (ALL)

by differentially expressed peptides and proteins- Mesenchymal stem cells and wnt-pathway regulation

Selected Publications:von Neuhoff N, Kaiser T, Wittke S, Krebs R, et al. Rapid Commun. Mass Spectrom2004; 18: 149-156Janke, V., von Neuhoff, N., Schlegelberger, B., Leyhausen, G., Geurtsen, W.Biomaterials. 2004; 25(19):4573-80.Ritgen M, Stilgenbauer S, von Neuhoff N, Humpe A, et al. Blood. 2004; 104:2600-2.Rudolph C, Steinemann D, von Neuhoff N, Gadzicki D, et al. Cancer GenetCytogenet. 2004; 153(2):144-50.Cario G, Stanulla M, Fine BM, Teuffel O, Neuhoff NV, et al. Blood. 2005;105(2):821-6.Dammann CE, Meyer M, Dammann O, von Neuhoff N. Biol Neonate.

2006;89(2):126-32

First name:Nils

Last name:von Neuhoff




Further information:www.mh-hannover.de/institute/zellpathologie

Department and function:Head, Biotechnology; FAL

Education:1973-1978 Veterinary Sciences, Veterinary University Hannover1978-1980 PhD thesis1985/86 Texas A&M University, College of Veterinary

Medicine1989: Habilitation Veterinary University Hannover1994: Apl. Professor for Reproductive Biology Veterinary

University Hannover

Positions:1980-1987: Scientist at the Institute for Animal Science1987-now: Head of Dept. Biotechnology at the Institute

Major research interests:Molecular regulation of preimplantation developmentTransgenesis in domestic species, Use of agricultural animals forbiomedical applications, Aspects of somatic cloningGenetic diversity

Selected Publications:Oropeza A, Wrenzycki C, Herrmann D, Hadeler KG, Niemann H. Biol Reprod. 2004; 70(6):1634-43.Niemann H. Proc Natl Acad Sci U S A. 2004; 101(19):7211-2Kues WA, Niemann H Trends Biotechnol. 2004; 22(6):286-94.Wrenzycki C, Herrmann D, Lucas-Hahn A, Lemme E, Korsawe K, Niemann H Anim Reprod Sci. 2004; 82-83:593-603. Kues WA, Petersen B, Mysegades W, Carnwath JW, Niemann H. Biol Reprod. 2005; 72(4):1020-8Wrenzycki C, Herrmann D, Lucas-Hahn A, Korsawe K, Lemme E, Niemann H.Reprod Fertil Dev. 2005; 17(1-2):23-35.Kues WA, Carnwath JW, Niemann H. Reprod Fertil Dev. 2005;17(1-2):125-34.Yadav PS, Kues WA, Herrmann D, Carnwath JW, Niemann H. Mol Reprod Dev. 2005;72(2):182-90.Holker M, Petersen B, Hassel P, Kues WA, Lemme E, Lucas-Hahn A, Niemann H.Cloning Stem Cells. 2005;7(1):35-44.Somfai T, Dinnyes A, Sage D, Marosan M, Carnwath JW, Ozawa M, Kikuchi K, Niemann H. Theriogenology. 2006 Feb 4;

First name:Heiner

Last name:Niemann

Acad. Title:Prof. Dr. med.vet. Dr.habil.

Address:Dept. BiotechnologyInstitute for Animal Science, MarienseeFAL, Hoeltystr. 1031535 Neustadt

Phone and e-mail:++49-(0)[email protected]

Further information:www.tzv.fal.de

Department and function:Department of Cellular ChemistryJunior Professor

Education:1994 PhD in Biochemistry at Lille Universiy, France

Positions:1995-1996: Postdoctoral position at University College London, UK1997-1999: Postdoctoral position at University of Dundee, UK2000: Maternity break2001: Marie Curie Fellow at Wageningen Research Center,

The Netherlands2002: Research Scientist, Cellular Chemistry, Hannover

Medical School2003- present: Junior Professor in Parasitology

Cellular Chemistry, Hannover Medical School

Major research interests:Analysis of the glycosylation pathways of eukaryotic pathogenssuch as the parasite Leishmania major and the fungus AspergillusfumigatusGalactofuranose metabolism; Nucleotide sugar transportersDesign and testing of drug leads in collaboration with other laboratories

Selected Publications:Bakker H, Kleczka B, Gerardy-Schahn R, Routier FH. (2005). Biol Chem., 386(7), 657-661.Tiralongo J, Ashikov A, Routier FH, Eckhardt M, Bakker H, Gerardy-Schahn R, von Itzstein M (2006). Glycobiology, 16(1), 73-81Ashikov A, Routier FH, Fuhlrott J, Helmus Y, Wild M, Gerardy-Schahn R, Bakker H(2005). J Biol Chem., 280(29), 27230-27235 Higson AP, Ross AJ, Tsvetkov YE, Routier FH, Sizova OV, Ferguson MA, NikolaevAV (2005). Chemistry, 11 (7), 2019-2030.Routier FH, Bakker H, Oelmann S, Jordi W, Lommen A, Gerardy-Schahn R, Bosch D (2005). Glycobiology, 15(2), 193-201.

First name:Françoise

Last name:Routier




Further information:www.mh-hannover.de/institute/zellulaere_ chemie

Department and function:Department of Gastroenterology, Hepatology and EndocrinologyTeam Leader

Education:1997 Medical Doctor, Georg-August-University Göttingen2003 Habilitation in Experimental Gastroenterolgy, MHH

Positions:1998-2000: Postdoc with RA DePinho:

1. Albert-Eonsytein-college of Medicine, Bronx, New York2. Dana Faber Cancer Institute, Boston, MA

2001: Research Group Leader on Senescence, Aging and Carcinogenesis funded by the Emmy-Noether-Program of the DFG

Major research interests:1. Exploring the role of telomere shortening in A) Senescence, Aging, and Regeneration and B) Induction of chromosomal instability and Cancer2. Identification of organ and tissue specific Aging Markers3. Exploring new model organisms for aging research

Selected Publications:Rudolph KL, Chang S, Lee H-W, Blasco M, Gottlieb GJ, Greider C, DePinho RA. Cell96: 701-712, 1999.

Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Science 2000;287:1253-8.

Rudolph KL, Millard M, Bosenberg MW, DePinho RA. Nat Genet. 2001; 28:155-9.

Wiemann SU, Satyanarayana A, Tsahuridu M, Tillmann HL, et al. FASEB J. 2002;16:935-42.

Satyanarayana A, Wiemann SU, Buer J, Lauber J, et al. EMBO J. 2003; 22:4003-4013

Satyanarayana A, Greenberg RA, Schaetzlein S, Buer J, et al. MCB 2004; 24:5459-74.Schaetzlein S, Lucas-Hahn A, Lemme E, Kues WA, et al. PNAS 2004; 101:8034-8.Wiemann SU, Satyanarayana A, Buer J, Kamino K, et al. Oncogene 2005; 24(9):1501-9.Lechel A, Satyanarayana A, J u Z, Plentz RR, et al. EMBO Rep. 2005; 6(3):275-81Schaetzlein S, Rudolph KL. Reprod Fertil Dev. 2005;17(1-2):85-96.Plentz RR, Lankisch TO, Basturk M, Muller CC, Kirchhoff T, Gebel M, Bleck JS,

Kubicka S, Manns MP, Meier PN, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(7):1134-6.

Plentz RR, Tillmann HL, Kubicka S, Bleck JS, Gebel M, Manns MP, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(9):1422-8.

Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL. Hepatology. 2005; 42(5):1127-36.

First name:K. Lenhard

Last name:Rudolph

Acad. Title:PD. Dr. med.

Address:OE 6811Hannover MedicalSchool


Department and function:Junior Professor of Molecular Hematology

Education:1997 PhD in Chemistry (Biological Chemistry), Johann

Wolfgang Goethe-University in Frankfurt/Main2002 Habilitation in Molecular Biology, Hannover Medical

School

Positions:1997-1998: Post-doc at the Beckman Research Institute of the City

of Hope, Dept. of Molecular Biology1998-2002 Post-doc at the Hannover Medical School, Dept. of

Hematology and Oncology2002-current: Junior Professor of Molecular Hematology at the

Hannover Medical School, Dept. of Hematology and Oncology

Major research interests:Gene silencing mediated by RNA interference (RNAi): functionalgenomics and therapeutic optionsLentiviral gene transfer into hematopoietic stem and precursor cells

Selected Publications:Scherr M., Battmer K., Blömer U., Schiedlmeier B., Ganser A., Grez M., Eder M. Blood 2002; 99: 709-712.Scherr M., Battmer K., Ganser A., Eder M. Cell Cycle 2003; 2: 251-257.Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., Eder M. Blood 2003;101:1566-1569.Scherr M., Battmer K., Dallmann I., Ganser A., Eder M. Oligonucleotides 2003; 13: 353-363.Scherr M., Battmer K., Schultheis B., Ganser A., Eder M. Gene Ther 2005; 12: 12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M.Blood. 2005 Nov 8;

First name:Michaela

Last name:Scherr




Further information:www.mh-hannover.de/kliniken/haemonko/AK_Scherr/index1.html

Department and function:Professor, Cardiology and Angiology

Education:1984-1990 Medical School, Albert Ludwigs

University Freiburg i. Br.1987-1990 Doctoral thesis: Role of the Renin-

Angiotensin System in Experimental Heart Failure.1992-1993 Clinical Residency, Dept. of Cardiology,

Freiburg, University Hospital1993-1996 Postdoc, Dept. Of Experimental

Pathology, EMORY University Atlanta, USA.1996- Dept. Of Cardiology and Angiology, MHH

Positions:1992-1993 Clincial Residency1993-1996 Post-doc1996-1999 Clinical Residency1999-2001 Research Associatesince 2001 Assistant Prof. of Medicine

Major research interests:Vascular biology and Signal transduction of G-Protein coupledreceptors. Experimental and clinical atherosclerosis research

Selected Publications:Krämer C, Sunkomat J, Luchtefeld M., Walden M., Forssmann WG., et al. Circ Res. 2002; 90(7):770-6.Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, et al. Circ Res. 2003; 92(11): e80-6 Luchtefeld M, Drexler H, Schieffer B. Biochem Biophys Res Commun. 2003; 308(3):668-72.Grote K, Drexler H, Schieffer B. Nephrol Dial Transplant. 2004; 19(4):770-3.Schieffer B, Bunte C, Witte J, Hoeper K, Boger RH, Schwedhelm E, Drexler H. J Am Coll Cardiol. 2004; 44(2):362-8Grote K, Bavendiek U, Grothusen C, Flach I, Hilfiker-Kleiner D, Drexler H, Schieffer B. J Biol Chem. 2004; 279(53):55675-81Schmidt B, Drexler H, Schieffer B. Am J Cardiovasc Drugs. 2004; 4(6):361-8.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22):3493-500Luchtefeld M, Grote K, Grothusen C, Bley S, Bandlow N, Selle T, Struber M, Haverich A, Bavendiek U, Drexler H, Schieffer B. Biochem Biophys Res Commun. 2005; 328(1):183-8.Grothusen C, Bley S, Selle T, Luchtefeld M, Grote K, Tietge UJ, Drexler H, Schieffer B. Atherosclerosis. 2005; 182(1):57-69.

First name:Bernhard

Last name:Schieffer

Acad. Title:PD Dr. med.


Phone and e-mail:++49-511-532 4666++49-511-532 [email protected]

Further information:www.mh-hannover.de/ kliniken/kardiologie/htm/ home.html

Department and function:Director, Cell and Molecular Pathology

Education:1975-1982 Studied medicine at the Ludwig Maximilian University

in Munich and the Christian Albrecht University of Kiel

Positions:1983-2000 Assistant, University Lecturer, then Professor at the

Institute of Human Genetics, University of Kiel1987-2000 Deputy Director of the Institute of Human Genetics,

University of Kiel2001-2003 Director of the Institute of Cell and Molecular

Pathology, Hannover Medical School

Major research interests:My main interests are tumor genetics, with particular emphasis on thedissection of tumorigenesis, development of new diagnostic tools, and on genetic counseling in hereditary cancer syndromes.

Selected Publications:Metzke-Heidemann S, Harder L, Gesk S, Schoch R, Jenisch S, et al. GenesChromosomes Cancer 2001; 31: 10-14 McPherson JD, Marra M, Hillier L, Rosenthal A, Wen G, et al. Nature 2001; 409: 934-41 Steinemann D, Gesk S, Zhang Y, Harder L, Pilarsky C, et al. Genes ChromosomesCancer. 2003; 37(4):421-6Wilkens L, Flemming P, Gebel M, Bleck J, Terkamp C, et al. Proc Natl Acad SciUSA. 2004;101(5):1309-14. Neuhoff N, Kaiser T, Wittke S, Krebs R, Pitt A, Burchard A, Sundmacher A, Schlegelberger B, Kolch W, Mischak H. Rapid Commun Mass Spectrom. 2004; 18(2):149-56Nippert I, Schlegelberger B; Consortium 'Hereditary Breast and Ovarian Cancer of The Deutsche Krebshilfe'. Community Genet. 2003;6(4):249-58.Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, et al. Genes Chromosomes Cancer. 2004; 41(3):257-65. Rudolph C, Steinemann D, Von Neuhoff N, Gadzicki D, et al. Cancer Genet Cytogenet. 2004; 153(2):144-50.Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, et. Al. Cancer Genet Cytogenet. 2005;159(2):164-7.Wilkens L, Gerr H, Gadzicki D, Kreipe H, Schlegelberger B. Virchows Arch. 2005; 447(3):586-92.Rudolph C, Hegazy AN, von Neuhoff N, Steinemann D, Schrock E, Stripecke R, Klein C, Schlegelberger B. Cancer Genet Cytogenet. 2005; 161(1):51-6.Rudolph C, Liehr T, Steinemann D, Emura M, Daibata M, Matsuo Y, et al. CytogenetGenome Res. 2006;112(3-4):213-21.

First name:Brigitte

Last name:Schlegelberger

Acad. Title:Prof. Dr..



Further information:www.mh-hannover.de/institute/zellpathologie/

Department and function:Director, Clinical ImmunologyChairman of the MD/PhD Program

Education:1976 M.D., Medical School of the Rheinische Friedrich-

Wilhelms-Universität Bonn1977 Masters of Psychology, Rheinische Friedrich-Wilhelms-

Universität Bonn

Positions:1978-83 Instructor in Medicine, Medical School of the University

of Bonn1986-94 Associate Professor of Medicine and Immunology,

Hannover Medical School1995- Head, Professor of Medicine and Immunology, Dept.

Clinical Immunology, Hannover Medical School

Major research interests:Fc receptors, regulation and activation, role in pathogenesis of diseases; activation mechanisms of human natural killer cells; pathogenesis of vasculitis and chronic rheumatoid arthritis; immunotherapy (cytokinesand immunoglobulins); immunodeficiencies, AIDS - pathogenesis and treatment; clinical therapy studies

Selected Publications:Behrens GM, et al. Eur J Med Res. 2003;8(5):221-5.Werwitzke S, et al. Clin Exp Immunol. 2003;133(3):334-43. Drescher B, et al. Immunology. 2003;110(3):335-40Ulbricht KU, et al. Arthritis Rheum. 2003; 48(12):3542-3.Baumann U, et al. Arch Immunol Ther Exp (Warsz). 2003;51(6):399-406Jacobs R, et al. J Clin Immunol. 2004; 24(3):281-6Momot T, et al. Arthritis Rheum. 2004; 50(5):1561-5Stoll M, et al. Autoimmun Rev. 2004; 3(4):243-9Tillmann HL, et al. AIDS Care. 2004; 16(6):736-43Jacobs R, et al. Mol Immunol. 2005; 42(2):239-49Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Koch S, et al. Genes Immun. 2005; 6(5):445-7.Mobius U, et al. J Acquir Immune Defic Syndr. 2005; 39(2):174-80.Rihl M, et al. J Infect. 2005 Nov 4;Kumar V, et al. J Clin Invest. 2006; 116(2):512-20.

First name:Reinhold Ernst

Last name:Schmidt




Further information:www.mh-hannover.de/kliniken/immunwww-mh-hannover.de/studium/phd

Department and function:Director, Human Genetics

Education:1966-1973 Universities of Freiburg and Basel, Medicine

Positions: 1988-1990 Professor of Human Genetics, Berlin1990- Professor of Human Genetics, Director and Chair, MHH

Major research interests:Molecular Basis of Inherited Disease, Genetics of Behavior in Subhuman Primates, Structure and Ethics of Genetic Service Provision

Selected Publications:Krawczak and Schmidtke: DNA-Fingerprinting, Bios, Oxford (1998)Trefilov, Berard, Krawczak and Schmidtke, Behavior Genet. 2000; 30: 295.Rommel, Karck, Haverich, Schmidtke, Arslan-Kirchner, Hum. Mutat 2002; 20: 406Schubert S, Skawran B, Dechend F, Nayernia K, Meinhardt A, et al. Biol Reprod. 2003; 69(3):968-75.Pabst B, Arslan-Kirchner M, Schmidtke J, Miller K. Cytogenet Genome Res. 2003; 103(1-2):3-7Schmidtke J, Kuhnau W, Wand D, Edelmann J, Szibor R, Krawczak M Prenat Diagn. 2004; 24(8):662-4.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78Krawczak M, Trefilov A, Berard J, Bercovitch F, et al. Biol Reprod. 2005; 72(5):1109-13.Singh KK, Schmidtke J. Immunogenetics. 2005; 57(3-4):289-92.Skawran B, Schubert S, Dechend F, Vervoorts J, Nayernia K, Luscher B, Schmidtke J. Mol Cell Biochem. 2005; 276(1-2):159-67.Singh KK, Ristau S, Dawson WW, Krawczak M, Schmidtke J. Exp Eye Res. 2005; 81(4):401-6.Trefilov A, Croucher PJ, Krawczak M, Schmidtke J. Twin Res Hum Genet. 2005; 8(6):551-2.

First name:Jörg

Last name:Schmidtke


Address: OE 6300Hannover Medical School


Further information:www.human-genetik.net

Department and function:Director, Virology

Education:1980 MD Mainz1986 Habilitation Innsbruck

Positions:1996 MRCPath, London, 2003 FRCPath, London,

Major research interests:Kaposi‘s sarcoma – associated herpesvirus/human herpesvirus 8

Selected Publications:Greensill J, Sheldon J, Renwick NM, Beer B, Norley S, et al. J. Virol. 2000; 74:1572-1577.Luppi M, Barozzi P, Schulz TF, et al. N Engl J Med 2000; 343: 1378-1385Viejo-Borbolla A, Kati E, Sheldon J, Nathan K, Mattsson K, et al. J.Virol. 2003; 77(12):7093-100.Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF. J Virol. 2003; 77(17):9346-58.Viejo-Borbolla A, Schulz TF. AIDS Rev. 2003; 5(4):222-9Henke-Gendo C, Schulz TF, Hoeper MM. N Engl J Med. 2004; 350(2):194-5Henke-Gendo C, Schulz TF. Curr Opin Infect Dis. 2004; 17(1):53-7Dedicoat M, Newton R, Alkharsah KR, Sheldon J, et al. J Infect Dis. 2004; 190(6):1068Viejo-Borbolla A, Pizzato M, Blair ED, Schulz TF. Virus Res. 2005;108(1-2):45-55.Viejo-Borbolla A, Thomas P, Blair ED, Schulz TF. J Gen Virol. 2005;86:2469-80.Henke-Gendo C, Mengel M, Hoeper MM, Alkharsah K, Schulz TF. Am J Respir CritCare Med. 2005; 172(12):1581-5.Viejo-Borbolla A, Ottinger M, Bruning E, Burger A, Konig R, Kati E, Sheldon JA, Schulz TF. J Virol. 2005; 79(21):13618-29.Alkharsah KR, Dedicoat M, Deluca DS, Schulz TF, Blasczyk R. Tissue Antigens. 2006; 67(2):170-2

First name:Thomas F.

Last name:Schulz

Acad. Title:Prof. Dr. med., FRCPath



Department and function:Group Leader, Transplant Laboratory

Education:1983 Degree of „Diplom-Biologe“ (Masters Degree in

Biology), University of Braunschweig

1987 Degree of „Dr.rer.nat.“ (PhD), University of Hannover

1994 Habilitation; Venia legendi for Immunology, Hannover Medical School (MHH)

Positions:1983-1987 Research Assistant, MHH

1987-1990 Research Associate, MHH

1990-1991 Fellowship of the German Research Council (DFG), National Jewish Center for Immunology, Denver

1991- Group leader, Transplant Laboratory, MHH

1999- Professor of Immunology

Major research interests:Transplant Immunology/Xenotransplantation: Analysis of human anti-pig T cell responses, development of immunomodulatory antibodies, immunological monitoring of transplant recipients.Analysis of T cell activation in the human: Signal transduction, role of cell surface molecules (CD28, CD45), CD45 polymorphisms.

Selected Publications:Siefken R, Klein-Heßling S, Serfling E, Kurrle R, Schwinzer R. J Immunol 1998; 161:1645-1651 Jacobsen M, Schweer D, Ziegler A, et al. Nature Gen 2000; 26:495-499Niemann H, Verhoeyen E, Wonigeit K et al. Transplantation 2001; 72:1898-906 Dulat H, von Grumbkow C, Baars W, Schröder N, Wonigeit K, Schwinzer R. Eur J Immunol 2001; 31: 2217-2226Schwinzer R, Witte T, Hundrieser J, et al. Genes Immun 2003; 4:168-169Bedke T, Baars W, Schwinzer R Ann Transplant. 2003; 8(3):35-8Do HT, Baars W, Schwinzer R. Transplant Proc. 2005; 37(1):51-2.Do HT, Baars W, Borns K, Windhagen A, Schwinzer R. J Immunol. 2006; 176(2):931-8.

First name:Reinhard

Last name:Schwinzer

Acad. Title:Prof. Dr.rer.nat.



Further information:www.mh-hannover.de/kliniken/visceralchirurgie/

Department and function:Gastroenterology, Hepatology & EndocrinologyAttending in medicine and GI, principal investigator

Education:1977 -1985 Study of Medicine at the Ludwig-

Maximilian‘s University, Munich1985 Doctoral thesis2000 Venia legendi for international medicine

Positions:1985 - 1987 Postdoc, Dept. of Pharmacology, MHH1987 – 1988 Postdoc., Dig. Dis Center, Beth Israel Hospital, Boston1988 – 1995 Resident in Internal medicine and GI, Technical

University of Munich1995 - 2002 Attending, GI Division, Eberhard-Karls University,

Tübingen

Major research interests:1.Structure-function relationsships and protein-protein interactions in the regulation of the transport proteins for intestinal salt absorption and anion secretion.2.Mechanisms of volume regulation in gastrointestinal cells.3.Adaptive mechanisms in the gastrointestinal tract after selectiveknockout of transport and regulator proteins which are important in gastrointestinal salt and nutrient transport.

Selected publications:Jacob P, Rossmann H, Lamprecht G, Kretz A, Neff C, et al. Gastroenterology 2002;122(3):709-24Lamprecht G, Heil A, Baisch S, Lin-Wu E, Yun CC, et al.. Biochemistry 2002;41(41):12336-42. Bachmann O, Rossmann H, Berger UV, Colledge WH, Ratcliff R, et al. Am. J.Physiol. 2003; 284(1):G37-45.Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J PhysiolGastrointest Liver Physiol. 2003; 285(5):G887-97.Fahrmann M, Kaufhold M, Pfeiffer AF, Seidler U. Br J Pharmacol. 2003; 139:545-54Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J Physiol Gastrointest Liver Physiol. 2003; 285(5):G887-97Bachmann O, Riederer B, Rossmann H, Groos S, et al. Am J Physiol Gastrointest Liver Physiol. 2004; 287(1):G125-33.Schwab A, Rossmann H, Klein M, Dieterich P, Gassner B, Neff C, Stock C, Seidler U. J Physiol. 2005;568(Pt 2):445-58Tuo B, Riederer B, Wang Z, Colledge WH, Soleimani M, Seidler U. Gastroenterology. 2006;130(2):349-58

First name:Ursula

Last name:Seidler




Further information:www.mh-hannover.de/ kliniken/gastro/gastro.htm

Department and function:Institute for Transfusion Medicine

Education:1996 MD, Friedrich-Alexander-University

Erlangen2002 Medical specialist in transfusion medicine2003 W1-Professor for molecular immunohematology

Positions:1996-1998: Intern, Clinic I for Internal Medicine, Clinical Center

Fuerth1998-2001: Resident, Department of Hematology, Oncology and

Blood Bank, Humboldt-University Berlin1997-2000: Resourch Group Leader, Institute for Transfusion

Medicine, Hanover Medical School, Hanover, Germany2003-recent: W1-Professor, Institute for Transfusion Medicine,

Hanover Medical School, Hanover, Germany

Major research interests:Molecular biology of erythrocyte proteinsDecreasing Immunogenicity of Progenitor Cells by Regulating MHC Expression

Selected Publications:Seltsam A, Hallensleben M, Kollmann A, Blasczyk R. Blood 2003; 102: 3035-42.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45:960-8.Seltsam A, Das Gupta C, Wagner FF, Blasczyk R. Transfusion. 2005;45:359-65.Wagner FF, Blasczyk R, Seltsam A. Transfusion 2005;45:1331-4.Figueiredo C, Seltsam A, Blasczyk R. J Mol Med. In press.

First name:Axel

Last name:Seltsam

Acad. Title:Prof. Dr.med.



Further information:www99.mh-hannover.de/institute/transfusion/transfusionsmedizin/

Department and function:Assistant Professor, Virology

Education:1982 – 1988 University of Bonn, Biology1988 – 1989 Columbia University, New York, NY, USA

Immunology1989 - 1993 European Molecular Biology Laboratory, Heidelberg,

Cell Biology

Positions:1993 - 1997 Postdoc and Staff Scientist, Yale University,

New Haven, CT, USA, Dept. Cell Biology1997 – 2002 Group leader, Biochemistry Dept., MHH

Major research interests:Our group is interested in the cell biology of complex DNA viruses. How does a virus get access to a cell, disassemble to uncover its genome for replication, and how is – within a couple of hours – the viral program switched to virus assembly and egress? We have developed several in vivo and in vitro motility assays to analyse the cell biology of Herpes Simplex Virus and particularly the microtubule-mediated capsid transport by digital video microscopy. Using these assays, we characterize cytosolic host factors as well as structural viral proteins important in HSV1 entry and egress.

Selected Publications:Sodeik, Doms, Ericsson, Hiller, Machamer, van' t Hof, et al. J of Cell Biology 1993;121:521-541.Sodeik, Ebersold, Helenius. J of Cell Biology 1997; 136:1007-1021.Ojala, Sodeik, Ebersold, Kutay, Helenius. Mol & Cell Biology 2000; 20:4922-4931.Döhner, Wolfstein, Prank, Echeverri, Dujardin, Vallee, & Sodeik. Molecular Biology Cell 2002; 13:2795-2809.Mabit H, Nakano MY, Prank U, Saam B, Dohner K, et al. J Virol. 2002; 76(19):9962-71Sodeik B. J Cell Biol. 2002; 159(3):393-5.Marozin S, Prank U, Sodeik B. J Gen Virol. 2004; 85(Pt 4):775-86.Haas M, Siegert M, Schurmann A, Sodeik B, Wolfes H. Biochemistry. 2004; 43(25):8152-9.Dohner K, Sodeik B. Curr Top Microbiol Immunol. 2005;285:67-108.Wolfstein A, Nagel CH, Radtke K, Dohner K, Allan VJ, Sodeik B. Traffic. 2006; 7(2):227-37Radtke K, Dohner K, Sodeik B. Cell Microbiol. 2006; 8(3):387-400.

First name:Beate

Last name:Sodeik

Acad. Title:HD Dr. rer.nat.



Further information:www.mh-hannover.de/institute/virologie/

Department and function:Group Leader, Pediatric Nephrology and Metabolic Diseases,Consultant for Transplant and Nephrology Ward, Dialysis and Outpatient Service

Education:1975-1983 Medical Schools at Bochum, Stanford and Hamburg1983-85 Clinical Anesthesia

Positions:1985-1986 Pediatrics and Transplant Medicine Heidelberg 1986-1993 Pediatrics, Intensive Care and Pediatric Nephrology,

UKE Hamburg1993-1996 Research Fellow and Deputy Chief of Lab. Div. Of

Immunology, TB Strom Beth Israel Deaconess MedicalCenter, Harvard Medical School, Boston

1996-1997 Clinical Consultant Pediatric Nephrology Charite Berlin1998-now MHH

Major research interests:Transplant Immunology, Activation and Silencing of T-Cells, Quantitative Measurement of T-Cell ResponsesT-Cell Effectors, T-cell driven Primary Renal Diseases

Selected Publications:Strehlau J, Pavlakis M, et al. Proc Natl Acad Sci U S A. 1997;94(2):695-700. Strehlau J, Schachter AD, et. Al. Kidney Int. 2002;61(1):90-5.Pape L, Froede K, Strehlau J, Ehrich JH, Offner G. Pediatr Transplant. 2003; 7(4):302-4Melk A, Henne T, Kollmar T, Strehlau J, Latta K, et al. Kidney Int. 2003; 64(1):314-20.Pape L, Froede K, Strehlau J, Ehrich JH, Offner G. Pediatr Transplant. 2003; 7(4):302-4Pape L, Henne T, Offner G, Strehlau J, Ehrich JH, Mengel M, Grimm PC.Transplantation. 2003; 76(6):955-8.Henne T, Latta K, Strehlau J, Pape L, Ehrich JH, Offner G. Transplantation. 2003; 76(9):1326-30.Vannay A, Fekete A, Muller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabo AJ. Kidney Blood Press Res. 2004; 27(2):105-13.Pape L, Mengel M, Offner G, Melter M, Ehrich JH, Strehlau J. Pediatr Transplant. 2004; 8(6):565-70.

First name:Juergen

Last name:Strehlau



Phone and e-mail:0511-532-5597/[email protected]

Department and function:Professor, Human Genetics

Education:1980 – 1986 Free University Berlin, Medicine1988 MD1995 Specialist in Human Genetics2002 apl. Professorship

Positions:1987 Guestdoc, Cerrahpasha Medical Faculty,

Istanbul, Turky1988 – 1990 Postdoc, Inst. Humangenetics, FU BerlinSince 1991 Head of Molecular Diagnostics, Inst. Human

Genetics, Medical School Hannover

Major research interests:Molecular genetics of several monogenenic disorders like cysticfibrosis, haemochromatosis, morbus Osler, ataxia telangiectasia; neuro-and psychiatro-genetics, genetic screening

Selected Publications:M.Stuhrmann, L.Bashawri, MA.Ahmed, et al. British Journal of Haematology2001, 112: 616-620J.Ockenga, T.Dörk, M.Stuhrmann. Journal of Medical Genetics 2001; 38:243-244D.Heller, U.Schneider, J.Seifert, KF.Cimander, M.Stuhrmann. Addiction Biology2001, 6:183-187M.Schürmann, M.Albrecht, E.Schwinger, M.Stuhrmann. Eur J Hum Genet 2002;10:729-732Groman JD, Hefferon TW, Casals T, Bassas L, Estivill X, et al. Am J Hum Genet. 2004; 74(1):176-9.Gadzicki D, Muller-Vahl KR, Heller D, Ossege S, Nothen MM, Hebebrand J, Stuhrmann M. Am J Med Genet B Neuropsychiatr Genet. 2004; 127(1):97-103Grundmann K, Laubis-Herrmann U, Dressler D, Vollmer-Haase J, et al. Mov Disord. 2004; 19(11):1294-7.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78.Kuehl HK, Caselitz M, Hasenkamp S, Wagner S, El-Harith el-HA, Manns MP, Stuhrmann M. Hum Mutat. 2005; 25(3):320.Stuhrmann M, Hoy L, Nippert I, Schmidtke J. Genet Test. 2005 Fall;9(3):242-54.Hildebrand F, Pape HC, Griensven M, Meier S, Hasenkamp S, Krettek C, Stuhrmann M. Shock. 2005 Dec;24(6):518-22.

First name:Manfred

Last name:Stuhrmann-Spangenberg




Further information:www.mh-hannover.de/kliniken/humangenetik

Department and function:Head, ‘Clinical Reasearch Group Pseudomonas‘

Education and positions:1971 - 1976 study of biochemistry1974 - 1981 study of medicine1979 Dr. rer.nat.1984 Dr. med.1991 habilitation1992 professorship

Major research interests:• Genomics• Molecular pathology of cystic fibrosis• Pseudomonas genomics

Selected Publications:Wiehlmann L, Salunkhe P, Larbig K, Ritzka M, Tümmler B. Genome Letters 2002, 1: 123-130Larbig KD, Christmann A, Johann A, Klockgether J, et al. J Bacteriol. 2002; 184:6665-80.Weinel C, Nelson KE, Tümmler B. Environmental Microbiology 2002, 4: 809-818Kiewitz C, Tümmler B. Genome Letters 2002, 1: 111-114 Mekus F, Laabs U, Veeze H, Tümmler B. Hum Genet. 2003;112:1-11.Klockgether J, Reva O, Larbig K, Tummler B. J Bacteriol. 2004; 186(2):518-34.Mekus F, Tummler B Cystic fibrosis and NOS3. Am J Respir Crit Care Med. 2004; 169(2):319-2Mekus F, Tummler B. Am J Respir Crit Care Med. 2004;169(6):770Juhas M, Wiehlmann L, Huber B, Jordan D, et al. Microbiology. 2004; 150(Pt 4):831-41.Charizopoulou N, Jansen S, Dorsch M, Stanke F, Dorin JR, Hedrich HJ, Tummler B. BMC Genet. 2004; 5(1):6.Tummler B. J Cyst Fibros. 2004; Suppl 2:149-50Hug MJ, Tummler B. J Cyst Fibros.; 3 Suppl 2:157-8.Ritzka M, Stanke F, Jansen S, Gruber AD, et al. Hum Genet. 2004;115(6):483-91.Eberl L, Tummler B. Int J Med Microbiol. 2004; 294(2-3):123-31. Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS Microbiol Lett. 2005; 242(2):287-95.Salunkhe P, Topfer T, Buer J, Tummler B. Bacteriol. 2005; 187(8):2565-72.Reva ON, Tummler B. BMC Bioinformatics. 2005; 14;6:251.Stanke F, Becker T, Cuppens H, Kumar V, Cassiman JJ, Jansen S, Radojkovic D, Siebert B, Yarden J, Ussery DW, Wienker TF, Tummler B. Hum Genet. 2006;:1-13van Barneveld A, Stanke F, Ballmann M, Naim HY, Tummler B. Biochim BiophysActa. 2006 Feb 13;

First name:Burkhard

Last name:Tümmler

Acad. Title:Prof. Dr. Dr.



Further information:http://www. mh-hannover.de/ kliniken/kinderheilkunde/kfg/index.htm

Department and function: Director, Cell Biology

Education:1974: Diploma in Biology from the Free University Berlin1976: PhD obtained from the Free University Berlin1977-79: EMBO Fellow at the MRC Unit for Biophysics at

King‘s College in London, UK1979-82: Postdoctoral fellow (DFG) at the Biological

Laboratories at Harvard University (Cambridge, Ma)1982-84: Heisenberg-Fellow at the LMB in Cambridge (UK)

and the Max-Planck Institute for BiophysicalChemistry in Göttingen, Germany.

Positions:1986-92: Junior-Research group leader at the Max-Planck-

Institute for Biochemistry, Martinsried, Germany1992-1998: Associate Professor at the Dept. of pathology at

Washington University St. Louis, MOsince 1998: Professor for Cell Biology at MHH

Major research interests:Intracellular vesicular transport, functions of molecular chaperones

Selected Publications:Ungewickell, E., H. Ungewickell, et al. Nature 1995; 378: 632-635.Umeda, A., A. Meyerholz, et al. Eur J Cell Biol 2000; 79(5): 336-342.Scheele, U., C. Kalthoff, et al. J Biol Chem 2001; 276(39): 36131-36138.Kalthoff, C., S. Groos, et al. Mol Biol Cell 2002; 13(11): 4060-4073.Kalthoff, C., J. Alves, et al. J Biol Chem 2002; 277(10): 8209-8216.Scheele, U., J. Alves, et al. J Biol Chem. 2003; 278(28):25357-68.Hinrichsen, L., J. Harborth, et al. J Biol Chem. 2003; 278(46): 45160-70.Tsukada M, Prokscha A, Ungewickell E, Eichele G. J Biol Chem. 2005; 280(12):11361-8.Meyerholz A, Hinrichsen L, Groos S, Esk PC, Brandes G, Ungewickell EJ. Traffic. 2005; 6(12):1225-34.

First name:Ernst

Last name:Ungewickell



Phone and e-mail: ++49-511- 532 [email protected]

Further information:www.mh-hannover.de/institute/zellbiologie/

Department and function:Head, Central Institute for Biophysical and BiochemicalProcedures

Education:1968-1972 Chemistry, Technical University Braunschweig1972 – 1976 Dissertation, University Hannover

Positions:1973- Hannover Medical School

Major research interests:Protein nucleic acid and protein protein interactions Single strandedDNA binding proteins, analytical ultracentrifugation, biophysicalchemistry in solution

Selected Publications:Urbanke C, Wray J. Biochem J 2001; 358:165-73 Grazulis S, Deibert M, Rimseliene R, Skirgaila R, Sasnauskas G, et al. NucleicAcids Res 2002; 30(4):876-85Meyer S, Urbanke C, Wahle E.. Biochemistry 2002 ;41(19):6082-9Landwehr M, Curth U, Urbanke C. Biol Chem 2002; 383(9):1325-33 Schubert WD, Urbanke C, Ziehm T, Beier V, Machner MP,et al. Cell 2002; 111(6):825-36Witte G, Urbanke C, Curth U. Nucleic Acids Res. 2003; 31(15):4434-40Zaremba M, Urbanke C, Halford SE, Siksnys V J Mol Biol. 2004; 336(1):81-92Dreisewerd K, Rohlfing A, Spottke B, Urbanke C, Henkel W. Anal Chem. 2004; 76(13):3482-91Hansen T, Urbanke C, Schonheit P Extremophiles 2004; 8(6):507-12Maheswaran M, Urbanke C, Forchhammer K. J Biol Chem. 2004; 279(53):55202-10Yildiz O, Doi M, Yujnovsky I, Cardone L, Berndt A, Hennig S, Schulze S, Urbanke C, Sassone-Corsi P, Wolf E. Mol Cell. 2005; 17(1):69-82.Brasen C, Urbanke C, Schonheit P. FEBS Lett. 2005; 579(2):477-82.Urbanke C, Witte G, Curth U. Methods Mol Biol. 2005;305:101-14.

First name:Claus

Last name:Urbanke




Further information:http://www.mh-hannover.de/einrichtungen/bpc/

Department and function:Head of Division of Cell Biology and Immunology, German Research Centre for Biotechnology (GBF), Braunschweig

Education:1980 PhD in Cell Biology, Max-Planck-Institute for

Biophysical Chemistry, Göttingen; University Bonn1988 Habilitation in Cell Biology, University Bonn

Positions:1980-1982: Postdoc, National Cancer Institute, Bethesda,

USA (supported by EMBO fellowship)1983-1989: Research Assistant, Dept. of Biochemistry and Cell

Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen

1989-1993: Research Assistant, Project Leader in Dept. of Microbiology, German Research Centre for Biotechnology (GBF), Braunschweig

1994-1997: Acting head of the Division of Cell Biology and Immunology, German Research Centre for Biotechnology (GBF), Braunschweig

Since 1997: Full Professor (C4) for Cell Biology and Immunology, Technical University Braunschweig;Head of the Division of Cell Biology and Immunology, German Research Centre for Biotechnology (GBF), Braunschweig

Major research interests:Analysis of mechanisms of host/pathogen interactions signalling to the actin cytoskeleton; actin dynamics and cell motility.

Selected Publications:Krause, M., Sechi, A.S., Konradt, M., Monner, D., Gertler, F.B. & Wehland, J. J. Cell Biol. 2000; 149: 181-194.l, S., Lommel, S., Benesch, S., Rottner, K., Franz, T., Wehland, J. & Kühn, R. EMBO reports 2001; 2: 850-857.Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M., Domann, E., Wehland, J., Chakraborty, T. & Heinz, D.W. Cell 2002; 111: 825-836.Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J.,Stradal, T. E. EMBO J. 2004; 23(4):749-59Erck C, Peris L, Andrieux A, Meissirel C, Gruber AD, Vernet M, Schweitzer A, Saoudi Y, Pointu H, Bosc C, Salin PA, Job D, Wehland J. Proc Natl Acad Sci U S A. 2005; 102(22):7853-8.Dieterich G, Karst U, Fischer E, Wehland J, Jansch L. Nucleic Acids Res. 2006; 34(Database issue):D402-6.

First name:Jürgen

Last name:Wehland


Address:German Research Centre For Biotechnology (GBF)


Further information:www.gbf.de/forschergruppen/

Department and function: Head, Molecular Immunology, GBF

Education:1969-1978 Biology at the Free University of Berlin,

Special Studies: Molecular Biology and Genetics1974-1978 PhD Student at the Basel Institute for Immunology,

Basel, Switzerland

Positions:1978-1980 Research Associate at the Salk Institute for Biological

Studies, Department of Developmental Biology, San Diego,USA.

1980-1983: Scientific Assistant at the Friedrich-Miescher-Laboratorium of the Max-Planck-Gesellschaft, Tübingen, Germany.

1983-1989: Member at the Basel Institute for Immunology, Basel, Switzerland.

1989-1990: Visiting Professor at the Institute for Immunology and Rheumatology, University of Oslo, Oslo, Norway.

1990-present: Group leader at the GBF (Gesellschaft für Biotechnologische Forschung), Braunschweig, Germany.

Major research interests:Interaction of bacteria with the immune system.B cell development.

Selected PublicationsHense M, Domann E, S. Krusch S, Wachholz P, Dittmar KEJ, Rohde M, Wehland J, Chakraborty T, Weiss S. Cell. Microbiol. 2001; 3: 599-609 .Krusch S, E. Domann E, M. Frings M, A. Zelmer A, M. Diener M, T. Chakraborty T, S. Weiss S. J. Gene Med. 2002; 4, 655-667.Kretschmer K, Joungebloud A, Stopkowicz J, Stoermann B, Hoffmann R, Weiss S. J. Immunol. 2003; 171, 1192-201.Duber S, Engel H, Rolink A, Kretschmer K, Weiss S. Mol Immunol. 2003; 40(8):509-16Loessner H, Weiss S Expert Opin Biol Ther. 2004; 4(2):157-68Gekara NO, Weiss S. Biochem Soc Trans. 2004; 32(Pt 5):712-4.Zelmer A, Krusch S, Koschinski A, Rohde M, Repp H, Chakraborty T, Weiss S.J Gene Med. 2005; 7(8):1097-112.Samuelsson CV, Lienenklaus S, Muller PP, Zawatzky R, Hauser H, Weiss S.Biochem Biophys Res Commun. 2005; 335(2):584-9.Gekara NO, Jacobs T, Chakraborty T, Weiss S. Cell Microbiol. 2005;7(9):1345-56.

First name:Siegfried

Last name:Weiss

Acad. Title:Dr. rer.nat.

Address:AG MolekulareImmunologie,Mascheroder Weg 1a,38124 Braunschweig

Phone and e-mail:++49-0531-6181-230, [email protected]

Further information:[email protected]>-> Forschung Molecular Immunology

Department and function:Hematology, Hemostasis and OncologyScientist (bone marrow transplantation; Experimental Hematology)

Education:1987: MD Medical Faculty, University of Vienna, Austria1997: Habilitation in Experimental Hematology, Ludwig-

Maximillians-Universität / Munich2005: APL-Professor/ Experimental Hematology

Positions:1989-1992: Visiting fellow at the National Institutes of Health, NCI, Laboratory of Genetics1992-1993: Visiting associate (NIH/NCI/LG)1993-1998: Junior group leader GSF / Hämatologikum / Munich1998-1999: Invited scientist NIH/ National Heart/Lung/Blood

Institute1999-2002: Scientific and clinical staff fellow MHH/ Hematology2002-2003: Chief medical officer mosaiques diagnostics GmbH2003- recent: Scientific group leader MHH/ Hematology

Major research interests:Gene therapy of Graft versus Host diseaseStem Cell Transplantation: experimental and clinical application

Antigen-specific T-cells : therapeutic and researchProteomics in clinical research and diagnosis

Selected Publications:Bonini, C., Grez, M., Traversari, C., et al., Nature Med.; 9: 367-369 (2003)Weissinger E.M., Oettrich K., Evans C., Genieser H.G., Schwede F., Dangers M., Dammann E., Kolb H.J., Mischak H., Ganser A., Kolch W. Br J Cancer; (2004); 91:186-92Weissinger, E.M., Wittke, S., Kaiser, et al. Kidney Int.; (2004), 65: 2426-2434Kaiser T., Kamal H., Rank A., Kolb H.J., Holler E., Ganser A., Hertenstein B., Mischak H., Weissinger E.M. Blood; (2004) 104: 340-349Weissinger, E.M., Mischak, H. Transplant Med.; (2004) 16:1-5

First name:Eva

Last name:Mischak-Weissinger

Acad. Title:Prof. Dr.med univ.



Further information:www.mh-hannover.de/kliniken/haemonko

Department and function:Director, Pediatric Hematology/Oncology

Education:1969-1973 University Tübingen, Medicine1973-1975 Freie Universität Berlin1975 Dr. med.1976 Approbation1984 Board certified Pediatrician

Positions:1985-1987 Assist. Professor, Head Laboratory of

Cytokine Biology, Memorial Sloan KetteringCenter, New York

1987-1993 Professor for Pediatrics, MHH1993-1997 Professor for Specific Pediatric Hematology

and Oncology, MHHSince 1997 Head, Dept. of Pediatric Hematology/

Oncology, MHH

Major research interests:Cytokines, Hematopoietic stem cells, Bone marrow failuresyndromes, Leukemias

Selected Publications:Dale DC, et al. Am J Hematol. 2003; 72(2):82-93Lauten M, et al. Haematologica. 2003; 88(3):353-4Ballmaier M, et al. Ann N Y Acad Sci. 2003; 996:17-25.Beger C, et al. Br J Haematol. 2003; 122(2):245-52.Lauten M, et al. Leukemia. 2003; 17(8):1551-6Lauten M, et al. Haematologica. 2003; 88(11):1253-8.Grigull L, et al. Mycoses. 2003; 46(11-12):441-6.Zeidler C, et al. Rev Clin Exp Hematol. 2003; 7(1):72-83.Beger C, et al. Clin Cancer Res. 2004; 10(11):3780-7.Meissner B, et al. Leukemia. 2004; 18(11):1920-3.Kracht T, et al. Haematologica. 2004; 89(12):1492-7Cario G, et al.. Blood. 2005; 105(2):821-6Cloppenborg T, et al. Leukemia. 2005; 19(1):44-8Stanulla M, et al. Blood. 2005;105(2):906-7Cario G, et al. Br J Haematol. 2005; 129(2):275-8.Wang Z, et al. Ann N Y Acad Sci. 2005; 1044:29-40.Kardinal C, et al. Blood. 2006 Feb 1;107(3):1133-40.Germeshausen M, et al. Hum Mutat. 2006; 27(3):296.

First name:Karl

Last name:Welte


Address:OE 6780Hannover MedicalSchool


Further information:www.mh-hannover.de/Kliniken

Department and function:Professor, Dermatology

Education:Medical Doctor, Professor of Medicine

Positions:1985-1989 Post Doc in the Dept´s of Immunology in Hannover and in Goettingen1989-1994 Clinicail Education in the the Field of Dermatology in Hannoversince 1994: Registrar („Oberarzt“) in the Dept of Dermatology

Major research interests:Dermatoimmunology:Specifity and functions of skin infiltrating T-cells in eczemaRegulation of cytokine pattern in human T-cells and antigen-presentingcellsExpression and function of anaphylatoxin receptors

Selected Publications:Schmid-Ott G, Jaeger B, Meyer S, Stephan E, Kapp A, Werfel T. J Allergy ClinImmunol 2001; 108:455-462Gutzmer R, Langer K, Lisewski MS, Mommert S, Kapp A, Werfel T. J Allergy Clin Immunol 2002; 109:524-531Wittmann M, Kienlin P, Mommert S, Kapp A, Werfel T. J Immunol 2002; 168:3793-3800Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71. Weinmann O, Gutzmer R, Zwirner J, Wittmann M, Langer K, et al. Immunology2003; 110(4):458-65. Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004;111(4):435-43.Breuer K, Heratizadeh A, Wulf A, Baumann U, Constien A, Tetau D, Kapp A, Werfel T. Clin Exp Allergy. 2004; 34(5):817-24.Breuer K, Wulf A, Constien A, Tetau D, Kapp A, Werfel T. Allergy. 2004; 59(9):988-94.Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. Allergy Clin Immunol. 2004; 114(4):965-73.Gutzmer R, Diestel C, Mommert S, Kother B, Stark H, Wittmann M, Werfel T. J Immunol. 2005; 174(9):5224-32.Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Breuer K, Wittmann M, Kempe K, Kapp A, Mai U, Dittrich-Breiholz O, Kracht M, Mrabet-Dahbi S, Werfel T. Clin Exp Allergy. 2005; 35(8):1088-95.

First name:Werfel

Last name:Thomas

Acad. Title:Prof Dr. med.

Address:Dept DermatologyHannover MedicalSchoolRicklinger Str. 530449 Hannover

Phone and e-mail:[email protected]@gmx.de

Further information:http://www.klinikum-hannover.de/hkl/

Department and function:Juniorprofessor, Dermatology

Education:1989 Abitur, Gymnasium am Geroweiher,

Mönchengladbach1989-96 University Studies, Human Medicine, Heinrich-Heine

University, Düsseldorf

Positions:1996 – 2003 Residency, Department of Dermatology, Hannover

Medical School1999-2001 Postdoctoral Research (DFG Grant)12/2002 - Juniorprofessorin, Department of Dermatology,


Major research interests:Inflammation in eczematous skin diseases, regulation of IL-12, Th1 / Th2 „specific“ transcription factors, heat shock proteins in inflammatory skin diseases (HSP70, HSP27, gp96)

Selected Publications:Wittmann et al. Blood 1999; 94:1717Wittmann et al. Int Arch Allergy Immunol 2001; 124:346Wittmann et al. J Immunol 2002; 168:3793Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71.Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004; 111(4):435-43Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. J Allergy Clin Immunol. 2004; 114(4):965-73Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Purwar R, Werfel T, Wittmann M. J Invest Dermatol. 2006 Feb 16

First name:Miriam

Last name:Wittmann


Address:Ricklinger Str. 530449 Hannover

Phone and e-mail:0511 9246 278miriamwittmann@ web.de

Further information:http://www.klinikum-hannover.de/hkl/

Department and function:Head, "In Vitro Differentiation" Group, IPK Gatersleben

Education:1964-1969 Study of biology at the Univ. of Greifswald1970-1974 PhD thesis at the Institute of Genetics Gatersleben /

University of Halle1997 Habilitation and venia legendi ("Cell Biology") at the

Medical Faculty, University of Halle

Positions:1974-1991 Scientific co-worker (Mutagenesis and embryonic

stem cell research) Institute of Genetics, Gatersleben, Academy of Sciences

Since 1992 Head of the Research Group "In Vitro Differentiation", IPK Gatersleben

Major research interests:-Stem cell research: Embryonic and adult (intestinal, hematopoietic) stem cells-Stem cell differentiation into cardiac, skeletal, vascular smooth muscle, neuronal and pancreatic cells-Analysis of cell-cell and cell-matrix interactions-Embryotoxicity analysis in vitro using embryonic stem cells

Selected Publications:Blyszczuk P, Czyz J, Kania G, Wagner M, Roll U, St-Onge L, Wobus AM.Proc. Natl. Acad. Sci. USA 2003; 100:998-1003Czyz J, Wiese C, Rolletschek A, Blyszczuk P, Cross M, Wobus AM. Biol Chem. 2003; 384(10-11):1391-409.Kania G, Blyszczuk P, Czyz J, Navarrete-Santos A, Wobus AM.Methods Enzymol. 2003; 365:287-303Czyz J, Nikolova T, Schuderer J, Kuster N, Wobus AM. Mutat Res. 2004; 557(1):63-74.Rolletschek A, Blyszczuk P, Wobus AM.Toxicol Lett. 2004;149(1-3):361-9. Kania G, Blyszczuk P, Wobus AM. Int J Dev Biol. 2004; 48(10):1061-4.Kania G, Blyszczuk P, Jochheim A, Ott M, Wobus AM. Biol Chem. 2004; 385(10):943-53Blyszczuk P, Asbrand C, Rozzo A, Kania G, St-Onge L, Rupnik M, Wobus AM.. Int J Dev Biol. 2004 Dec;48(10):1095-104.Czyz J, Guan K, Zeng Q, Wobus AM. Int J Dev Biol. 2005;49(1):33-41.Kania G, Corbeil D, Fuchs J, Tarasov KV, Blyszczuk P, Huttner WB, Boheler KR, Wobus AM. Stem Cells. 2005 Jun-Jul;23(6):791-804.Nikolova T, Czyz J, Rolletschek A, Blyszczuk P, Fuchs J, Jovtchev G, Schuderer J, Kuster N, Wobus AM. FASEB J. 2005 Oct;19(12):1686-8.

First name:Anna M.

Last name:Wobus

Acad. Title:PD Dr. rer. nat.

Address:Institute of Plant Genetics (IPK Gatersleben)Corrensstr. 306466 Gatersleben


Further information:www.ipk-gatersleben.de