1

William A. Gray, MD FACC FSCAI

Curriculum Vitae

EDUCATION

1976 – 1980 Dickinson College Carlisle, Pennsylvania Bachelor of Science in Chemistry with Honors

1980 – 1984 Temple University School of Medicine Philadelphia, Pennsylvania Doctor of Medicine

POSTGRADUATE TRAINING

07/1984 – 06/1987 Intern/Resident in Internal Medicine Brown University/Rhode Island Hospital Providence, Rhode Island

Chief Resident in Internal Medicine 07/1987 – 06/1988

Brown University/Rhode Island Hospital Providence, Rhode Island

Clinical/Research Fellow in Cardiology 07/1988 – 06/1991

Brown University/Rhode Island Hospital Providence, Rhode Island

Interventional Fellow in Cardiology 07/1991 – 06/1992

Brown University/Rhode Island Hospital Providence, Rhode Island

EMPLOYMENT

07/1984 – 06/1992 Rhode Island Hospital Providence, RI

07/1992 – 07/1999 Southwest Cardiology Associates Albuquerque, New Mexico

2

08/1999 - 06/2005 Swedish Medical Center Seattle, Washington 07/2005 - 12/2015 Columbia University New York, NY 1/2016 – present Main Line Heath/Lankenau Heart Institute Wynnewood, PA BOARD CERTIFICATION 1985 National Board of Medical Examiners American Board of Internal Medicine 1987 -Internal Medicine 1991, 2001, 2016 -Cardiology 1999, 2009 -Interventional Cardiology

American Board of Vascular Medicine

2004 -Vascular Medicine 2004 -Endovascular Medicine MEDICAL LICENSURE 2016 State of Pennsylvania, License No. MD456945

2005 State of New York, License No. 236296 1999 State of Washington, License No. 37638 2001 Nuclear Medicine

1992 State of New Mexico, License No. 92-234 1993 Nuclear Medicine

1986 State of Rhode Island, License No. 6844 ACADEMIC POSITIONS 1987-1992 Clinical Instructor of Medicine Brown University Providence, Rhode Island 1993-1999 Assistant Clinical Professor of Medicine University of New Mexico Albuquerque, New Mexico 2005-2009 Assistant Professor of Medicine

3

Columbia University College of Physicians and Surgeons

New York, NY 2009-2015 Associate Professor of Medicine

Columbia University College of Physicians and Surgeons

New York, NY HOSPITAL ACTIVITIES

1987 – 1991 Intern Selection Committee

Brown University/Rhode Island Hospital 1993 – 1997 Chairman, Cardiac Clinical Operations 1993 – 1997 Director, Coronary Care Units 1996 – 1997 Vice-Chair, Division of Cardiology

Presbyterian Hospital, Albuquerque, New Mexico

1994 – 1998 Medical Director, Project Heart Start (Mass CPR training) Albuquerque, New Mexico

1998 – 1999 Board of Directors (founding member) Heart Hospital of New Mexico Albuquerque, New Mexico 1999-2005 Director, Endovascular Care Swedish Medical Center Seattle, Washington 2005 –2015 Director, Endovascular Services New York-Presbyterian Hospital Columbia University Medical Center New York, New York 2016 – present System Chief, Division of Cardiovascular Diseases,

Main Line Health President, Lankenau Heart Institute Wynnewood, PA

RELATED WORK EXPERIENCE 1987 – 1992 Emergency Physician

St. Joseph's Hospitals Providence, Rhode Island

1988 – 1990 Medical Co-Director, Ambulatory Services Notre Dame Hospital

4

Central Falls, Rhode Island

1991 – 1992 Emergency Physician Bergstrom Air Force Base

Austin, Texas

1996 – 1999 Director of Intervention and Research Southwest Cardiology Associates Albuquerque, New Mexico 1998 – 1999 President, Southwest Cardiology Associates

Private practice group Albuquerque, New Mexico

2002-2004 Medical Director, Coronary Division

Abbott Vascular Redwood City, CA HONORS/AWARDS Pioneers in Performance: Data analysis WL Gore

Veith Symposium 2012

The Haffenreffer Foundation Award for Outstanding Resident in Internal Medicine Brown University/Rhode Island Hospital 1987 Horace Elton Rogers Award for Excellence in Chemistry Dickinson College 1979

EDITORIAL BOARD Journal of the American College of Cardiology,

Interventions Catheterization and Cardiac Interventions

Endovascular Today JOURNAL REVIEWER Circulation Journal of the American College of Cardiology

Journal of the American Medical Association Catheterization and Cardiac Interventions

5

RESEARCH ACTIVITY

National/International Principle Investigator

Coronary Intervention

2005-2007 ZoMAXX II [Abbott Vascular] Prospective, multicenter, randomized FDA IDE PMA

trial of ZoMAXX novel drug-eluting coronary stent vs.TAXUS stent in patients with de novo coronary disease

Endovascular Intervention

2001-2003 ARCHeR [Guidant] Prospective, single-arm 3-phase FDA IDE PMA study

of surgical risk patients carotid artery stenting for device approval of the Acculink stent and Accunet carotid protection of high

2004-2016 ACT I [Abbott Vascular] Asymptomatic Carotid Trial: (Executive Committee) Prospective, multicenter, randomized FDA IDE PMA

trial of carotid stenting vs. endarterectomy in asymptomatic patients

2005-2007 CAPTURE [Abbott Vascular] Single-arm prospective post-approval study of the

Carotid RX ACCULINK/ACCUNET to uncover unanticipated and rare events

2006-2008 CAPTURE 2 [Abbott Vascular] Single-arm prospective post-approval study of the

Carotid RX ACCULINK/ACCUNET to uncover unanticipated and rare events: second phase

2008-2010 PROTECT [Abbott Vascular] (Executive Committee) Prospective single-arm multicenter FDA IDE 510K

study of the NAV 6 Emboshield embolic protection device in patients with carotid stenosis at high surgical risk

2009-2010 COMPLETE SE [Medtronic] Prospective single-arm multicenter FDA IDE PMA

study of the COMPLETE SE nitinol self-expanding stent system for the treatment of iliac stenosis and occlusion

6

2009-2010 ACTIVE [Medtronic] Prospective single-arm multicenter FDA IDE PMA

study of the ACTVE balloon expandable cobalt chromium stent system for the treatment of iliac stenosis and occlusion

2009-2010 EMBOLDEN [WL GORE] Prospective single-arm multicenter IDE 510K study of

the WL GORE embolic protection filter in patients with carotid stenosis at high surgical risk

2009-2010 STROLL [Cordis/Johnson &Johnson]

Prospective single-arm multicenter IDE PMA study of the SMART self-expanding nitinol stent for the treatment of SFA and popliteal occlusive disease

2008-2012 CHOICE [Abbott Vascular] Prospective single-arm post-market study of the (Executive Committee) ACCULINK/ACCUNET and XACT/NAV 6 carotid

stent systems for carotid stenting in patients at high surgical-risk for

endarterectomy 2009-present ACST 2 (Trial Management Committee)

Asymptomatic Carotid Stenosis Trial 2. UK-based (Oxford) prospective multi-center international study of carotid stenosis treatment in asymptomatic patients randomizing 5000 patients between stenting and surgery.

2011 PFAST-CTO [Bridgepoint Medical] Prospective multicenter single arm IDE 510K study of

the Bridgepoint total occlusion system for SFA/popliteal occlusions

2011-2016 OPEN [Flexible Stent Solutions] Prospective multicenter single-arm IDE PMA study of

the Flexstent in patients with SFA/popliteal stenosis or occlusion

2013-2016 SCAFFOLD [WL Gore] Prospective, single-arm, multicenter IDE PMA study

of a novel mesh covered stent for the prevention of embolic events from carotid artery stenting

7

2015-present TOBA II [Intact Vascular] Prospective, single-arm, multicenter FDA IDE PMA

study of a novel device for dissection treatment in SFA/popliteal arteries

2015-present IMPERIAL [Boston Scientific Corporation] Prospective, randomized, multicenter international

trial to evaluate the safety and efficacy of a new self-expanding drug-eluting stent vs. existing drug-eluting stent in SFA/popliteal arteries

2017- PAD 3 [Shockwave Medical] Prospective, multicenter randomized study of a

lithoplasty balloon for the treatment of heavily calcified SFA/popliteal arteries

Planned start: 2017 EnligHTNed [St. Jude] Prospective, randomized, blinded/sham-controlled,

multicenter IDE PMA study of radiofrequency renal denervation catheter in patients with resistant hypertension

Planned start: 2017 ILLUMINATE-BTK[Spectranetics] Prospective, randomized, multicenter IDE PMA study

of drug coated balloon effectiveness in patients with infra-popliteal disease/critical limb ischemia

Structural Heart Intervention Planned start: 2018 SentreHeart Prospective, randomized, multicenter study of left

atrial appendage occlusion in oral anticoagulant ineligible patients

Site Principle Investigator

Coronary

SCORES [Boston Scientific] Radius self-expanding coronary stent TRAP trial [Microvena] Coronary saphenous vein graft vascular filter

Endovascular Intervention

8

CREST– [NIH/NHLBI] Carotid Revascularization Endarterectomy vs. Stent Trial

SAPPHIRE Randomized high surgical risk carotid stent trial [Cordis/Johnson&Johnson] ARCHER [Guidant] High Surgical Risk Carotid Stent Trial using the

Acculink stent and Accunet carotid protection device CABERNET [EndoTex/BSC] Carotid Artery Revascularization Using the EPI

FilterWire EX and the NexStent CREATE [eV3] Carotid Revascularization with ev3 Arterial

Technology Evolution MAVeRIC [Medtronic] Self-Expanding Carotid Stent System with Distal

Protection In the Treatment of Carotid Stenosis Carotid Wallstent Carotid Stent vs. CEA Randomized Trial [Schneider/BSC] Memotherm [BARD] Phase I Carotid Stent Trial CASES-PMS Carotid Artery Stenting with Embolic Protection Surveillance: Post [Cordis/Johnson&Johnson] Marketing Study CAPTURE [Abbott Vascular] Carotid RX ACCULINK/ACCUNET Post-Approval

Trial to Uncover Unanticipated and Rare Events

MOBILE [Novoste] Brachytherapy to prevent restenosis following peripheral arterial intervention

VIBRANT [WL GORE] Viabahn vs. nitinol stents for SFA intervention

STROLL [Cordis] SMART Stent for SFA/popliteal stenosis and

occlusion

CAPTURE 2 [Abbott Vascular] Carotid RX ACCULINK/ACCUNET Post Approval Trial to Uncover Unanticipated and Rare Events: second phase

CHOICE [Abbott Vascular] Carotid Stenting for High Surgical-Risk Patients

EMBOLDEN [WL Gore] EMBOLic Filter in Carotid StENting for High Risk

Surgical Subjects ACTIVE [Medtronic] Iliac IDE single arm study (balloon-expandable stent) COMPLETE SE [Medtronic] Iliac IDE single arm study (self-expanding stent)

9

PROTECT [Abbott Vascular] Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy

CENTRAL [CR BARD] Evaluation of Device for crossing chronic total

occlusions in the SFA/popliteal arteries OPEN [Flexible Stent Solutions] Flexstent for the treatment of SFA/popliteal stenosis

and occlusion PFAST-CTO[Bridgepoint Medical]

Bridgepoint total occlusion system for treatment of SFA/popliteal occlusions

IN.PACT II [Medtronic] Drug-coated balloon for the treatment of

SFA/popliteal disease

Endovascular

TandemHeart Percutaneous CardiacAssist LVAD in cardiogenic shock

PLAATO [eV3] Percutaneous Left Atrial Appendage Transcatheter

Occlusion Using the X-Caliber System, A Feasibility Study

EVEREST 1 [evalve] Feasibility study of the edge-to-edge repair of mitral

valve regurgitation using the Evalve Cardiovascular Valve Repair System

PROTECT AF [Atritech] Watchman left atrial appendage system for embolic

protection in patients with atrial fibrillation EVEREST II [evalve] Randomized study of the Evalve Endovascular Valve

Edge-to-Edge Repair study in patients with severe mitral regurgitation

REALISM Continued access registry of Evalve Endovascular

Valve Edge-to-Edge Repair in high-surgical risk patients with severe mitral regurgitation

COAPT Randomized study of Evalve Endovascular Valve

Edge-to-Edge Repair in high surgical risk patients with severe functional mitral regurgitation

10

RESEARCH-RELATED ACTIVITIES 2014- Chair, Clinical Events Committee

Shockwave EU study 2012-2014 Co-chair, Peripheral Vascular Academic Research

Consortium 2009-2010 Chair, Data Safety and Monitoring Biofreedom Trial 2005-2015 Interventional Management Committee, ACT I trial

2003-2008 Interventional Management Committee, NIH CREST

study

2005-2009 Member, Clinical Events Committee Fortron AAA study

2003-2007 Chairman, Clinical Events Committee

PLAATO study 1999-2001 Data Safety and Monitoring Board, BARD

Memotherm Iliac Stent Trial COURSE DIRECTORSHIPS 2005-2015 Course Co-Director Transcatheter Therapeutics (TCT) 2011, 2015-present Course Co-Director

International Symposium on Endovascular Therapies (ISET)

Miami, FL 2011, 2014 Course Co-Director Cardiovascular Research Technologies (CRT) Washington DC

2011-2012 Course Co-Director

International Congress for Endovascular Specialists (iCON)

Phoenix, AZ 2003 – 2005 Program Director

The Status of Carotid Stenting American College of Cardiology

11

2001-2008 Course Director

Science Innovation Synergy (SIS) Seattle, WA

2000 – 2001 Chair, John Locke Conference Swedish Medical Center

Seattle, WA 1994 – 1997 Wilson Lectureship Planning Committee Presbyterian Hospital,

Albuquerque, New Mexico 1993 – 1999 Co-Director, Santa Fe Symposium Santa Fe, New Mexico INDUSTRY EXPERIENCE 2011-present Founder/CEO, Vadiswire Corporation 2009-2014 Consultant/Scientific Advisory Board, Covidien 2008-present Scientific Advisory Board, Medtronic 2005-present Scientific Advisory Board, Cordis/Cardinal Health

2005- 2009 Scientific Advisory Board, Ovalis Corporation

2004-2010 Co-Founder, CoAptus Corporation

2004-2011 Scientific Advisory Board (chair),

Pathway Medical

2003-present Strategic Scientific Advisory Board, Abbott Vascular 2002–2005 Scientific Advisory Board, Rubicon Medical Corp. 2003–2005 Medical Advisory Board, The Medicines Company 2002-2004 Medical Director, BEACH carotid trial, Boston

Scientific

1997–1999 Consultant, Schneider USA 1995–1999 Consultant, BARD USA, 1999–2005 Consultant, Guidant Corporation

12

PATENTS (USPTO) 2002 Temporary Vascular Filter Guide Wire

PFO closure devices (co-holder CoAptus corporation)

Pending PFO closure devices (co-holder Ovalis corporation) Pending Multi-wire guidewire support system

Pending DEVICE/PROCEDURE PROCTOR 2005-2008 Cordis/Johnson and Johnson Carotid Stent System 2005-2008 Guidant/Abbott Vascular Corporation Carotid System 2003-2004 NMT PFO device 1997-1999 Schneider USA Carotid Stent 1995-1996 Johnson and Johnson Interventional Coronary Stent 1995-2003 Boston Scientific/Heart Technology Rotablator SOCIETIES/OTHER AFFILIATIONS 2010-present Co-chair, SCAI Carotid and Neurovascular

Committee 2009-2012 Board of Directors

American Board of Vascular Medicine

2005 Fellow, Society of Cardiac Angiography and Intervention (FSCAI)

2003-2005 American College of Cardiology PVD Committee member, SCAI representative 2001-2007 American Heart Association Stroke Council 1995 – 1997 American Heart Association New Mexico Chapter, Board of Directors 1995 – 1997 Medical Advisory Board, New Mexico Emergency

Medical System

13

1993 Fellow, American College of Cardiology 1992 – 1999 Member, Greater Albuquerque Medical Association 1988 Member, American Heart Association Circulation

Council 1987-present Member, American College of Physicians

Abstracts

1. Gray WA, Bier J, Gewirtz H. Does EDRF Play an Important Role in Regulation of Basal Arteriolar Tone in the Normal Coronary Circulation? American Heart Association Scientific Sessions 1990, Dallas.

2. Gray WA, Gewirtz H. 99mTc-teboroxime Versus Thallium for Myocardial Perfusion Imaging in the Presence of a Coronary Stenosis. American Heart Association Scientific Sessions 1990, Dallas.

3. Gray WA, Gewirtz H. Evidence of Differential Wash-Out of 99mTc-teboroxime from Normal and Ischemic Myocardium. American College of Cardiology Scientific Sessions 1991, Atlanta.

4. Gray WA, Bier J, Gewirtz H. Vasodilator Reserve Persists Distal to a Chronic Coronary Artery Stenosis Despite Reduced Myocardial Blood Flow. American College of Cardiology Scientific Sessions 1991, Atlanta.

5. Gray WA, Emin S, Williams DO. Marked Diameter Enlargement in Polyolefincopolymer Angioplasty Balloons on Repeat Inflation. American Heart Association Scientific Sessions 1991, Anaheim.

6. Gray WA, Emin S, Williams DO. The Influence of Angioplasty Balloon Material on the "Dog-Bone" Phenomenon. American College of Cardiology Scientific Sessions 1992, Dallas.

7. Gray WA, Berman SF, Gewirtz H. Comparison of 99mTc-teboroxime and Thallium for Assessment of Relative Coronary Flow Reserve in the Presence of Coronary Artery Stenosis. American College of Cardiology Scientific Sessions, 1992 Dallas.

8. Gray WA, Emin S, Williams DO. Force Generated by Angioplasty Balloons is a Function of Balloon Material. American Heart Association Scientific Sessions, 1992 New Orleans.

9. Gray WA, Berman MS, Sharaf BL, Williams DO. Balloon Size is an Independent Determinant of Dilating Force in Coronary Angioplasty. The Society for Cardiac Angiography and Intervention Annual Meeting 1993, San Antonio.

14

10. Gray, WA, Sharaf, BL, Berman MS, Emin SA, Williams DO. Stenosis Severity: An Independent Determinant of the Dilating Force Generated by Coronary Angioplasty Balloons. The Society for Cardiac Angiography and Intervention Annual Meeting 1993, San Antonio.

11. Gray WA, Gazzal ZMB, White HJ. The Effects of Balloon Length and Angle Severity on the Straightening Force Developed by Polyethylene Tenephalate (PET) Angioplasty Balloons. American Heart Association Scientific Sessions 1993, Atlanta.

12. Gray, WA, McGuire, BJ, Benge, JW, Sanchez, R. Latent Thrombosis in a Pacemaker Patient. American College of Physicians New Mexico Regional Meeting, Albuquerque, New Mexico 1994.

13. White, H, Gray WA., Sexson, R. Longterm Outcome of Advanced Interventional Coronary Procedures. American College of Physicians Regional Meeting. Albuquerque, New Mexico 1995.

14. Gray, W, White H, Barrett D, et al. Stenting for Carotid Artery Stenosis: The New Mexico Experience. American College of Physicians New Mexico Regional Meeting 1996.

15. Gray WA, White HJ, Barrett, DM, et al. Hemodynamic Consequences of Carotid Stenting. American Heart Association Scientific Sessions 1997, Orlando.

16. Gray WA, Barrett DM, Turner R. Carotid Stenting and Endarterectomy: A Cost Comparison. American College of Cardiology, Annual Scientific Session 1998, Atlanta.

17. New G, Roubin GS, Iyer SS, Wholey MH, Diethrich EB, Hopkins LN, et al. Immediate and long-term outcomes following carotid stenting for patients with restenosis post endarterectomy. American Heart Association Scientific Sessions 1999, Atlanta.

18. Spencer MP, Moehring M, White J, Heidmiller C, Gray W, Reisman M, Olsen J, Kraybill K. Power m-mode transcranial Doppler assessment of cerebral microemboli during percutaneous closure of patent foramen ovale. American College of Cardiology Annual Scientific Session March 2002, Atlanta.

19. Reisman MR, Gray WA. Use of a head-mounted confluent display of fluoroscopic and echocardiographic images to enhance operator feedback during catheter-deployed closures of cardiac septal defects. Medicine Meets Virtual Reality 2002, Newport Beach, CA.

20. Reisman, M, Gray, WA, Sievert, H, Kramer, P, Block, P, DiMario, C, Bartorelli, A, Della Bella, P, Omran, H, Poppas, A, Williams, DO, Skanes, A, Meier, B, Nakai, T, Lesh, M. An Endovascular approach to stroke prevention an atrial fibrillation: Results of the multicenter PLAATO (Percutaneous Left Atrial Appendage Transcatheter Occlusion) feasibility trial. American College of Cardiology Annual Scientific Session March 2003, Chicago.

15

21. Sievert, H, Lesh, M, Ostermayer, S, Billinger, K, Trepels, T, Omran, H, Bartorelli, A, Della Bella, P, Nakai, T, Reisman, M, Gray, WA, DiMario, C, Block, P, Kramer, P, Williams, DO, Poppas, A, Skanes, A, Krumsdorf, U, Scherer, D. Percutaneous left atrial appendage transcatheter occlusion to prevent stroke in patients with atrial fibrillation: Initial results from the multicenter feasibilty trial. American College of Cardiology Annual Scientific Session March 2003, Chicago.

22. Gray, WA, Jesurum, J, Spencer, M, Diehl, L, Krabill, K, Olsen, J, Smith, C, Christofferson, RD, Reisman, M. Transcatheter Patent Foramen Ovale Closure is Efficacious in Patients with Coexisting Atrial Septal Aneurysm. American Stroke Association Annual Session, February 2004, San Diego.

23. Jesurum, J, Reisman, M, Spencer, M, Olsen, J, Krabill, K, Diehl, L, Smith, C, Gray, WA. Patent Foramen Ovale Size Does Not Predict Cerebral Embolic Conductance In Patients With Cryptogenic Stroke. American Stroke Association Annual Session, February 2004, San Diego.

24. Reisman, M, Jesurum, Spencer, M, Krabill, K, Diehl, L, Olsen, J, Aurora, S Smith, C, Christofferson, RD, Gray, WA. Migraine Relief Following Transcatheter Closure of Patent Foramen Ovale. American College of Cardiology Annual Meeting, March 2004, New Orleans

25. Gray, WA, Prospective Clinical Trial for Carotid Stenting with Embolic Protection in High Surgical Risk Patients; The ARCHeR* Trial: Final Results. American College of Cardiology Annual Meeting, March 2004, New Orleans.

26. Bayard, Y, Buscheck, F, Ostermayer, S, Reisman, M, Lesh, M, Nakai, T, Gray, WA, Omran, H, Kramer, P, Bartorelli, A, Della Bella, P, Block, P, DiMario, C, Matthews, R, Moses, J, Poppas, A, Williams, D, Skanes, A, Meier, B, Teirstein, P, Billinger, P, Trepels, T, Fleschenberg, D, Sievert, H. Percutaneous Left Atrial Appendage Transcatheter Occlusion (PLAATO™) to Prevent Stroke in Patients With Atrial Fibrillation: Interim Results of the Multicenter Feasibility Trial. American College of Cardiology Annual Meeting, March 2004, New Orleans

27. Brian F. Gage, MD, MSc; Carl van Walraven, MD, FRCPC, MSc; Lesly Pearce, MS; Robert G. Hart, MD; Peter J. Koudstaal, MD; B.S.P. Boode, MD; Palle Petersen, MD, PhD. Selecting Patients With Atrial Fibrillation for Anticoagulation Stroke Risk Stratification in Patients Taking Aspirin. American Heart Association 2004

28. Herrmann, H, Wasserman, H, Whitlow, P, Block, P, Gray, WA, Foster, E, Feldman, T. Percutaneous Edge-to-Edge Mitral Valve Repair: Preliminary Results of the EVEREST-I Study. American Heart Association 2004

29. Reisman, M, Gray, WA, Kramer, P, Matthews, R, Block, P, Omran, H, Bartorelli, A, Colombo, A, Moses, J, Williams, D, Meier, B, Skanes, A, Teirstein, P, Sievert, H. Safety and Efficacy of Percutaneous Left Atrial Appendage Transcatheter Occlusion (PLAATO™) in Non-Anticoagulation Eligible Patients with Atrial Fibrillation and High Risk for Stroke. American Heart Association 2004

16

30. Block, P, Reisman, M, Gray, WA, Kramer, P, Matthews, R, Omran, H, Sievert, H, Bartorelli, A, Colombo, A, Casale, P, Moses, J, Williams, D, Meier, D, Skanes, A, Teirstein, P. Interim PLAATO Therapy Results Suggest Marked Stroke Rate Reduction

31. Block, P, Reisman, M, Gray, WA, Kramer, P, Matthews, R, Omran, H, Sievert, H, Bartorelli, A, Colombo, A, Casale, P, Moses, J, Williams, D, Meier, D, Skanes, A, Teirstein, P. Interim PLAATO Therapy Results Suggest Marked Stroke Rate Reduction. American College of Cardiology Annual March 2005, Orlando.

32. Feldman, T, Wasserman, H, Herrmann, H, Gray, WA, Whitlow, T, Block, P, Foster, E, St.Goar, F. Percutaneous Edge-to-Edge Mitral Valve Repair Using the Evalve Clip: Update of the EVEREST Phase I Clinical Trial. American College of Cardiology Annual March 2005, Orlando.

33. Rohatgi, S, Wasserman, H, Block, P, Gray, WA, Whitlow, P, Wiegers, S, Foster, E, Feldman, T, Herrmann, H. Mitral Stenosis is Not Produced by Percutaneous Edge-to-Edge Mitral Valve Repair of Mitral Regurgitation. American Heart Association 2005

34. Jesurum, J, Reisman, M, Krabill, K, Spencer, M, Olsen, JV, Gray, WA. Migraineurs with Patent Foramen Ovale Have Greater Cerebral Embolic Conductance than Non-Migraineurs. American Heart Association 2005

35. Herrmann, H, Wasserman, H, Whitlow, P, Block, P, Gray, WA, Foster, E, Rohatgi, S, St. Goar, F, Feldman, T. Percutaneous Edge-to-Edge Mitral Valve Repair Using the Evalve MitraClip™: Initial One Year Results of the EVEREST Phase I Clinical Trial. American Heart Association 2005

36. Jesurum, J, Reisman, M, Spencer, M, Olsen, JV, Krabill, K, Gray, WA. Migraine Relief following Transcatheter Closure of Patent Foramen Ovale Occurs in the Presence of Residual Right to Left Shunt. American Heart Association 2005

37. Weisz, G, Gray, WA, Hathaway, L, Knipper, P, Bertling, C, Gong, M, Stone, GW, Leon, MB. Interventional Vascular Simulation Is Mostly Beneficial for Training of Fellows and Teaching the Use of New Devices and Procedures. American College of Cardiology Annual March 2006

38. Harms, V, Reisman, M, Jesurum, J, Fuller, C, Spencer, M, Olsen, JV, Krabill, K, Gray, WA. Transcatheter Closure of Patent Foramen Ovale in Patients With Paradoxical Embolism: Longitudinal Risk of Recurrent Stroke American College of Cardiology Annual March 2006

39. Scheinert, D, Graziani, L, Peeters, P, Sultan, S, Gray, WA, Laird, J, Gershony, G. Results From the Multi-Center Registry of the Novel AngioSculpt Scoring Balloon Catheter for the Treatment of Infra-Popliteal Disease. American Heart Association 2006

40. Carabello, B, Foster, E, Whitlow, P, Herrmann, H, Wasserman, H, Block, P, Kramer, P, Gray, WA, Rinaldi, M, Bailey, S, Smalling, R, Glower, D, Feldman,

17

T. Reverse Remodeling of the Left Ventricle after Percutaneous Mitral Valve Repair Using the Evalve MitraClip Device. American Heart Association 2006

41. Foster E., Tunugunta A., Whitlow PL., Block P., Herrman HC., Kramer P., Smalling R., Bailey S., Rinaldi MJ., Gray WA., et al. Significant Reduction in Mitral Regurgitation Six Months Following Percutaneous Mitral Valve Repair with the MitraClip™. Journal of the American College of Cardiology March 2007, Volume 49 No. 9 supplement A.

42. Travis J Bench, Ajay J Kirtane, Luis Gruberg, Lisa Wilbert, David L Brown, William A Gray, Allen Jeremias. Adherence to ACC/AHA Guidelines for the Management of Patients with Peripheral versus Coronary Artery Disease in a Tertiary Care Center. AHA Scientific Sessions 2008.

43. Kiesz RS, Schinert D, Peeters PJ, Bosiers M, O'Sullivan G, Sultan S, Turco MA, Gray WA, Laird JR, Malik A, Mewissen MW, Dave R, Das TS, Piemonte TC, Khanna P, Gershony G. Results from the International Registry of the AngioSculpt Scoring Balloon Catheter for the Treatment of Infra-Popliteal Disease. SCAI/ACC i2 March 2008.

44. Arjomand H, Gray W, Hymanson A, Petrovich L, LaBlanc P, Alani F, Surabhi S, Goldberg S, McCormick D. Outcome of carotid artery stenting in female versus male patients: A gender analysis of the CAPTURE-2 registry SCAI/ACC i2 March 2008

45. Helmi L. Lutsep, MD, Kirk Beach, PhD, MD, Gary Roubin, MD, Pierre Leimgruber, MD, Brajesh K. Lal, MD, William Gray, MD, Kenneth Rosenfield, MD, Robert Bergelin, MD, Jennifer Voeks, PhD, Mary Longbottom, BA, Robert W. Hobson II, MD, Thomas Brott, MD for the CREST Investigators. Carotid Luminal Diameter Changes from One Month to One Year after Stenting: CREST Lead-in Phase. ASA, San Diego February 2009.

46. Gray WA. Two-Year Interim Results from the Single-Arm Clinical Study of the Zilver® PTX® Drug-Eluting Peripheral Stent. SCAI Annual Meeting 2010 San Diego.

47. Brar SS, Izquierdo K, Schwartz J, Lam C, Saw A, Shen AJY, Chen R, Pfeffer TA, Jorgensen M, Khan S, Gray WA, Aharonian V, Mansukhani P. Relationship Between Aortic Diameter and Major Adverse Events in Type B Aortic Dissection. ACC Scientific Sessions. 2012 Chicago.

18

Original/Peer Reviewed Articles

1. Gray WA, Capone RJ, Most AS. Unsuccessful Emergency Medical Resuscitation - Are Continued Efforts in the Emergency Department Justified? N Engl J Med 1991; 325:1393-1398.

2. Gray WA, Gewirtz H. Comparison of 99mTc-teboroxime with thallium for myocardial imaging in the presence of a coronary artery stenosis. Circulation. 1991 Oct;84(4):1796-1807.

3. Gray WA, Capone RJ, Most AS. Resuscitation after Cardiac Arrest Outside the Hospital (letter). N Engl J Med 1991; Vol. 20; 325:1495-1497.

4. Gray WA. "Nearly successful" resuscitation. Lancet. 1993 Apr 3;341(8849):866.

5. Gray WA. Prehospital resuscitation. The good, the bad, and the futile. JAMA. 1993 Sep 22-29;270(12):1471-1472.

6. Mills I, Wrenn D, Sasken H, Gray W, Bier J, Levine D, Berman S, Gilson M, Gewirtz H. Adaptive Responses of Coronary Circulation and Myocardium to Chronic Reduction in Perfusion Pressure and Flow. Am J Physiol 1994 Feb;266 (2 Pt 2):H447-457.

7. Glazer S, Gray WA. Futile care. What is the endpoint of unsuccessful field resuscitation? Emerg Med Serv. 1995 Jul;24(7):65-6, 75.

8. Gray WA, DuBroff R, White H. A Common Clinical Conundrum. N Engl J Med, 1997; 336:1008-1011.

9. Gray WA, DuBroff R, White H. Carotid Stenting (letter). N Engl J Med, 1997; 337(6): 427-428.

10. Walji S, Peterson RJ, Neis P, DuBroff R, Gray WA, Benge W. Ultra-fast track hospital discharge using conventional cardiac surgical techniques. Ann Thorac Surg. 1999 Feb;67(2):363-9; discussion 369-370.

11. Gray WA, Barrett DM, Benge JW. Heart or head? N Engl J Med. 1999 Nov 4;341(19):1458-1462.

12. Wholey MH, Wholey M, Mathias K, Roubin GS, Diethrich EB, Henry M, Bailey S, Bergeron P, Dorros G, Eles G, Gaines P, Gomez CR, Gray B, Guimaraens J, Higashida R, Ho DS, Katzen B, Kambara A, Kumar V, Laborde JC, Leon M, Lim M, Londero H, Mesa J, Musacchio A, Myla S, Ramee S, Rodriquez A, Rosenfield K, Sakai N, Shawl F, Sievert H, Teitelbaum G, Theron JG, Vaclav P, Vozzi C, Yadav JS, Yoshimura SI. Global experience in cervical carotid artery stent placement. Catheter Cardiovasc Interv. 2000 Jun;50(2):160-7.

13. New G, Roubin GS, Iyer SS, Vitek JJ, Wholey MH, Diethrich EB, Hopkins LN, Hobson RW 2nd, Leon MB, Myla SV, Shawl F, Ramee SR, Yadav JS, Rosenfield K, Liu MW, Gomez CR, Al-Mubarak N, Gray WA, Tan WA, Goldstin JE, Stack RS. Safety, efficacy, and durability of carotid artery stenting for

19

restenosis following carotid endarterectomy: a multicenter study. J Endovasc Ther. 2000 Oct;7(5):345-352.

14. Gray WA. Successful resolution of a peripheral arterial in-stent thrombus in a patient with combined eptifibatide and thrombolytic therapy. J Invasive Cardiol. 2000 Dec;12 Suppl D:19D-20D.

15. Gray WA, White HJ Jr, Barrett DM, Chandran G, Turner R, Reisman M. Carotid stenting and endarterectomy: a clinical and cost comparison of revascularization strategies. Stroke. 2002 Apr;33(4):1063-1070.

16. Wang JC, Aucoin-Barry D, Manuelian D, Monbouquette R, Reisman M, Gray W, Block PC, Block EH, Ladenheim M, Simon DI. Incidence of aspirin nonresponsiveness using the Ultegra Rapid Platelet Function Assay-ASA. Am J Cardiol. 2003 Dec 15;92(12):1492-1494.

17. Reisman M, Gray WA. Vascular brachytherapy and the strontium vascular brachytherapy system. J Invasive Cardiol. 2003 Sep;15(9):520-522.

18. Casserly IP, Kereiakes DJ, Gray WA, Gibson PH, Lauer MA, Reginelli JP, Moliterno DJ. Point-of-care ecarin clotting time versus activated clotting time in correlation with bivalirudin concentration. Thromb Res. 2004;113(2):115-121.

19. Hanna IR, Kolm P, Martin R, Reisman M, Gray W, Block PC. Left atrial structure and function after percutaneous left atrial appendage transcatheter occlusion (PLAATO): six-month echocardiographic follow-up. J Am Coll Cardiol. 2004 May 19;43(10):1868-1872.

20. Gray WA. A Cardiologist in the Carotids. J Am Coll Cardiol. 2004 May 5;43(9):1602-1605.

21. Spencer MP, Moehring MA, Jesurum J, Gray WA, Olsen JV, Reisman M. Power m-mode transcranial Doppler for diagnosis of patent foramen ovale and assessing transcatheter closure. J Neuroimaging. 2004 Oct;14(4):342-349.

22. Reisman M, Christofferson RD, Jesurum J, Olsen JV, Spencer MP, Krabill KA, Diehl L, Aurora S, Gray WA. Migraine headache relief after transcatheter closure of patent foramen ovale. J Am Coll Cardiol. 2005 Feb 15;45(4):493-495.

23. Rosenfield K, Babb JD, Cates CU, Cowley MJ, Feldman T, Gallagher A, Gray W, Green R, Jaff MR, Kent KC, Ouriel K, Roubin GS, Weiner BH, White CJ. Clinical competence statement on carotid stenting: training and credentialing for carotid stenting--multispecialty consensus recommendations: a report of the SCAI/SVMB/SVS Writing Committee to develop a clinical competence statement on carotid interventions. J Am Coll Cardiol. 2005 Jan 4;45(1):165-174.

24. Ostermayer SH, Reisman M, Kramer PH, Matthews RV, Gray WA, Block PC, Omran H, Bartorelli AL, Della Bella P, Di Mario C, Pappone C, Casale PN, Moses JW, Poppas A, Williams DO, Meier B, Skanes A, Teirstein PS, Lesh MD, Nakai T, Bayard Y, Billinger K, Trepels T, Krumsdorf U, Sievert H. Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the

20

international multi-center feasibility trials. J Am Coll Cardiol. 2005 Jul 5;46(1):9-14.

25. Hara H, Virmani R, Ladich E, Mackey-Bojack S, Titus J, Reisman M, Gray W, Nakamura M, Mooney M, Poulose A, Schwartz RS. Patent foramen ovale: current pathology, pathophysiology, and clinical status. J Am Coll Cardiol. 2005 Nov 1;46(9):1768-76.

26. Gray WA. Proceedings of the TCT: endovascular interventional care evolves into multidisciplinary field. J Interv Cardiol. 2006 Jun;19(3):222-225.

27. Moussa ID, Gray WA. Peripheral arterial disease training: "Vascular medicine for the interventionalist". Future Cardiol. 2006 Sep;2(5):543-4.

28. Herrmann HC, Rohatgi S, Wasserman HS, Block P, Gray W, Hamilton A, Zunamon A, Homma S, Di Tullio MR, Kraybill K, Merlino J, Martin R, Rodriguez L, Stewart WJ, Whitlow P, Wiegers SE, Silvestry FE, Foster E, Feldman T. Mitral valve hemodynamic effects of percutaneous edge-to-edge repair with the MitraClip device for mitral regurgitation. Catheter Cardiovasc Interv. 2006 Nov 1

29. Gray WA, Hopkins LN, Yadav S, Davis T, Wholey M, Atkinson R, Cremonesi A, Fairman R, Walker G, Verta P, Popma J, Virmani R, Cohen DJ; ARCHeR Trial Collaborators. Protected carotid stenting in high-surgical-risk patients: the ARCHeR results. J Vasc Surg. 2006 Aug;44(2):258-68.

30. Gray WA, Yadav JS, Verta P, Scicli A, Fairman R, Wholey M, Hopkins LN, Atkinson R, Raabe R, Barnwell S, Green R. The CAPTURE registry: results of carotid stenting with embolic protection in the post approval setting. Catheter Cardiovasc Interv. 2007 Feb 15;69(3):341-8.

31. Harms V, Reisman M, Fuller CJ, Spencer MP, Olsen JV, Krabill KA, Gray WA, Jesurum JT.Outcomes after transcatheter closure of patent foramen ovale in patients with paradoxical embolism.Am J Cardiol. 2007 May 1;99(9):1312-5. Epub 2007 Mar 19.

32. Silvestry FE, Rodriguez LL, Herrmann HC, Rohatgi S, Weiss SJ, Stewart WJ, Homma S, Goyal N, Pulerwitz T, Zunamon A, Hamilton A, Merlino J, Martin R, Krabill K, Block PC, Whitlow P, Tuzcu EM, Kapadia S, Gray WA, Reisman M, Wasserman H, Schwartz A, Foster E, Feldman T, Wiegers SE. Echocardiographic guidance and assessment of percutaneous repair for mitral regurgitation with the Evalve MitraClip: lessons learned from EVEREST I.J Am Soc Echocardiogr. 2007 Oct;20(10):1131-40. Epub 2007 Jun 13.

33. Fairman R, Gray WA, Scicli AP, Wilburn O, Verta P, Atkinson R, Yadav JS, Wholey M, Hopkins LN, Raabe R, Barnwell S, Green R; for the CAPTURE Trial Collaborators. The CAPTURE registry: analysis of strokes resulting from carotid artery stenting in the post approval setting: timing, location, severity, and type. Ann Surg. 2007 Oct; 246(4):551-6; discussion 556-8.

34. Jesurum JT, Fuller CJ, Velez CA, Spencer MP, Krabill KA, Likosky WH, Gray WA, Olsen JV, Reisman M. Migraineurs with patent foramen ovale have larger

21

right-to-left shunt despite similar atrial septal characteristics. J Headache Pain. 2007 Sep;8(4):209-16. Epub 2007 Sep 24.

35. White CJ, Gray WA. Endovascular therapies for peripheral arterial disease: an evidence-based review. Circulation. 2007 Nov 6;116(19):2203-15.

36. Foster E, Wasserman HS, Gray W, Homma S, Di Tullio MR, Rodriguez L, Stewart WJ, Whitlow P, Block P, Martin R, Merlino J, Herrmann HC, Wiegers SE, Silvestry FE, Hamilton A, Zunamon A, Kraybill K, Gerber IL, Weeks SG, Zhang Y, Feldman T. Quantitative assessment of severity of mitral regurgitation by serial echocardiography in a multicenter clinical trial of percutaneous mitral valve repair. Am J Cardiol 2007;100:1577–1583.

37. Gray WA, Yadav JS, Verta P, Scicli A, Fairman R, Wholey M, Hopkins LN, Atkinson R, Raabe R, Barnwell S, Green R. The CAPTURE Registry: Predictors of outcomes in carotid artery stenting with embolic protection for high surgical risk patients in the early post-approval setting. Catheter Cardiovasc Interv. 2007 Nov 28;70(7):1025-1033

38. Pucelikova T, Mehran R, Kirtane AJ, Kim YH, Fahy M, Weisz G, Lansky AJ, Moussa I, Gray WA, Collins MB, Kodali SK, Stone GW, Moses JW, Leon MB, Dangas G. Short- and long-term outcomes after stent-assisted percutaneous treatment of saphenous vein grafts in the drug-eluting stent era. Am J Cardiol. 2008 Jan 1;101(1):63-8. Epub 2007 Nov 19.

39. Iyer SS, White CJ, Hopkins LN, Katzen BT, Safian R, Wholey MH, Gray WA, Ciocca R, Bachinsky WB, Ansel G, Joye JD, Russell ME; BEACH Investigators. Carotid artery revascularization in high-surgical-risk patients using the Carotid WALLSTENT and FilterWire EX/EZ: 1-year outcomes in the BEACH Pivotal Group. J Am Coll Cardiol. 2008 Jan 29;51(4):427-34.

40. Gray WA. Clinical trials: past, present, and future. Semin Vasc Surg. 2008 Jun;21(2):80-7.

41. Meyers PM, Schumacher HC, Gray WA, Fifi J, Gaudet JG, Heyer EJ, Chong JY. Intravascular Ultrasound of Symptomatic Intracranial Stenosis Demonstrates Atherosclerotic Plaque with Intraplaque Hemorrhage: A Case Report. J Neuroimaging. 2008 Oct 24.

42. White CJ, Beckman JA, Cambria RP, Comerota AJ, Gray WA, Hobson RW 2nd, Iyer SS; American Heart Association Writing Group. Atherosclerotic Peripheral Vascular Disease Symposium II: controversies in carotid artery revascularization. Circulation. 2008 Dec 16;118(25):2852-9. No abstract available.

43. Iyengar S, Gray WA. Use of magnetic guidewire navigation in the treatment of lower extremity peripheral vascular disease: Report of the first human clinical experience Catheter Cardiovasc Interv. 2009 May 1;73(6):739-44.

44. Iyengar S, Meyers PM, Goyal NK, Moses JW, MD, Gray WA. Novel Applications of Noncardiac Vascular Devices for the Treatment of Coronary Artery Pathology. J Invasive Cardiol. J Invasive Cardiol. 2009 Feb;21(2):60-4.

22

45. Gray WA, Chaturvedi S, Verta P. Current 30-Day Outcomes for Carotid Artery Stenting in 6,320 Patients with High Surgical Risk Features from a Prospective Multicenter Registry. Circ Cardiovasc Interv. 2009 Jun; 2(3):159-66. Epub 2009 Mar 6.

46. Moussa ID, Jaff MR, Mehran R, Gray W, Dangas G, Lazic Z, Moses JW. Prevalence and prediction of previously unrecognized peripheral arterial disease in patients with coronary artery disease: the Peripheral Arterial Disease in Interventional Patients Study. Catheter Cardiovasc Interv 2009 May 1;73(6):719-24.

47. Brar SS, Gray WA. Regarding "Risk-adjusted 30-day outcomes of carotid stenting and endarterectomy: Results from the SVS Vascular Registry". J Vasc Surg. 2009 May;49(5):1362; author reply 1362-3.

48. Holmes DR, Reddy VT, Turi ZG, Doshi SK, Sievert H, Buchbinder M, Mullin CM, Sick P; PROTECT AF investigators. Percutaneous closure of left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomized non-inferiority trial. Lancet.2009 Aug 15;374:534-42.

49. Feldman T, Kar S, Rinaldi M, Fail P, Hermiller J, Smalling R, Whitlow PL, Gray W, Low R, Hermann HC, Lim S, Foster E, Glower D; EVEREST investigations. Percutaneous mitral repair with the MitraClip System: safety and midterm durability in the initial EVEREST(Endovascular Valve Edge-to-Edge Repair Study) cohort. J Am Coll Cardiol. 2009 Aug 18;54(8):686-94.

50. Gaudet JG, Meyers PM, McKinsey JF, Lavine SD, Gray W, Mitchell E, Connolly ES Jr, Heyer EJ. Incidence of moderate to severe cognitive dysfunction in patients treated with carotid artery stenting. Neurosurgery. 2009 Aug;65(2):325-9;discussion 329-30.

51. Sommer R, Gray W. All defects of atrial septum are not created equally. Catheter Cardiovasc Interv. 2009 Sep1;74(3):527;author reply 528.

52. Brar SS, Gray WA, Dangas G, Leon MB, Aharonian VJ, Brar SK, Moses JW. Bifurcation stenting with drug-eluting stents: a systematic review and meta-analysis of randomised trials. EuroIntervention. 2009 Sep;5(4):475-84.

53. Zeller T, Krankenberg H, Steinkamp H, Rastan A, Sixt S, Schmidt A, Sievert H, Minar E, Bosiers M, Peeters P, Balzer JO, Gray W, Tubler T, Wissgott C, Schwarzwalder U, Scheinert D. One-year outcome of percutaneous rotational atherectomy with aspiration in infrainguinal peripheral arterial occlusive disease: the multicenter pathway PVD trial. J Endovasc Ther. 2009 Dec;16(6):653-62

54. Chaturvedi S, Matsumara JS, Gray W, Xu C, Verta P; on behalf of the CAPTURE 2 Investigators and Executive Committee. Carotid Artery Stenting in Octogenarians. Periprocedural Stroke Risk Predictor Analysis From the Multicenter Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events (CAPTURE 2) Clinical Trial. Stroke. 2010 Apr;41(4):757-64.

23

55. Hopkins LN, Roubin GS, Chakntoura EY, Gray WA, Ferguson RD, Katzen BT, Rosenfield K, Goldstein J, Cutlip DE, Morrish W, Lal BK, Sheffet AJ,Tom M, Hughes S, Voeks J, Kathir K, Meschia JF. Hobson RW 2nd, Brott TG. The Carotid Revascularization Endarterectomy versus Stenting Trial: Credentialing of interventionalists and final results of lead-in phase. J Stroke Cerebrovasc Dis.2010 Mar;19(2)153-62.

56. Roffi M, Sievert H, Gray WA, White CJ, Torsello G, Cao P, Reimers B, Mathias K, Setacci C, Schönholz C, Clair DG, Schillinger M, Grunwald I, Bosiers M, Abou-Chebl A, Moussa ID, Mudra H, Iyer SS, Scheinert D, Yadav JS, van Sambeek MR, Holmes DR, Cremonesi A. Carotid artery stenting versus surgery: adequate comparisons? Lancet Neurol. 2010 Apr;9(4):339-41.

57. Gray WA, Granada JC. Review article: Drug Coated Balloons for the Prevention of Vascular Restenosis. Circulation 2010 Jun 22;121(24):2672-80

58. Stenting versus endarterectomy for treatment of carotid-artery stenosis. Brott TG, Hobson RW 2nd, Howard G, Roubin GS, Clark WM, Brooks W, Mackey A, Hill MD, Leimgruber PP, Sheffet AJ, Howard VJ, Moore WS, Voeks JH, Hopkins LN, Cutlip DE, Cohen DJ, Popma JJ, Ferguson RD, Cohen SN, Blackshear JL, Silver FL, Mohr JP, Lal BK, Meschia JF; CREST Investigators. N Engl J Med. 2010 Jul 1;363(1):11-23. Epub 2010 May 26. Erratum in: N Engl J Med. 2010 Jul 29;363(5):498. N Engl J Med. 2010 Jul 8;363(2):198.

59. Matsumura JS, Gray WA, Chaturvedi S, Gao X, Cheng J, Verta P. Risk-Adjusted Stroke Outcomes Benchmarks for Carotid Artery Stenting with Distal Embolic Protection. J Vasc Surg. 2010 Sep;52(3):576-83, 583.

60. Safian RD, Jaff MR, Bresnahan JF, Foster M, Bacharach JM, Yadav J, Joye J, Myla S, Kassab E, Mann JT, Ansel GM. Protected carotid stenting in high-risk patients: results of the SpideRX arm of the carotid revascularization with ev3 arterial technology evolution trial. CREATE SpideRX Trial Investigators. J Interv Cardiol. 2010 Oct;23(5):491-8

61. Waseda K, Hasegawa T, Ako J, Honda Y, Grube E, Whitbourn R, Ormiston J, O'Shaughnessy CD, Henry TD, Overlie P, Schwartz LB, Sudhir K, Chevalier B, Gray WA, Yeung AC, Fitzgerald PJ; ZoMaxx I and II Trial Investigators. Comparison of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation: pooled IVUS results from the ZoMaxx I and II trials. Circ J. 2010 Oct 25;74(11):2334-9. .

62. Aronow HD, Gray WA, Ramee SR, Mishkel GJ, Schreiber TJ, Wang H. Predictors of Neurological Events Associated With Carotid Artery Stenting in High-Surgical-Risk Patients: Insights From the Cordis Carotid Stent Collaborative. Circ Cardiovasc Interv. 2010 Dec;3(6):577-84.

24

63. Gray WA, Rosenfield K, Jaff M, Chaturvedi S, Peng L, Verta P. Influence of Site and Operator Characteristics on Carotid Artery Stent Outcomes: Analysis of the CAPTURE 2 Clinical Trial. Cardiovasc Interv. 2011 Feb;4(2):235-46.

64. Neuroprotection during carotid artery stenting using the GORE flow reversal system: 30-day outcomes in the EMPiRE Clinical Study. Clair DG, Hopkins LN, Mehta M, Kasirajan K, Schermerhorn M, Schönholz C, Kwolek CJ, Eskandari MK, Powell RJ, Ansel GM; EMPiRE Clinical Study Investigators. Catheter Cardiovasc Interv. 2011 Feb 15;77(3):420-9.

65. Mahoney EM, Greenberg D, Lavelle TA, Natarajan A, Berezin RH, Ishak, KJ, Caro JJ, Yadav JS, Gray JS, Wholey M, Cohen DJ. Costs and Cost-Effectiveness of Carotid Stenting vs. Endarterectomy for Patients at Increased Surgical Risk: Results from the SAPPHIRE Trial. Catheter Cardiovasc Interv. 2011 Mar 1;77(4):463-72.

66. Percutaneous repair or surgery for mitral regurgitation. Feldman T, Foster E, Glower DD, Kar S, Rinaldi MJ, Fail PS, Smalling RW, Siegel R, Rose GA, Engeron E, Loghin C, Trento A, Skipper ER, Fudge T, Letsou GV, Massaro JM, Mauri L; EVEREST II Investigators. N Engl J Med. 2011 Apr 14;364(15):1395-406.

67. Current status of endovascular stroke treatment. Meyers PM, Schumacher HC, Connolly ES Jr, Heyer EJ, Gray WA, Higashida RT. Circulation. 2011 Jun 7;123(22):2591-601. Review.

68. Gray WA, Yeung AC, Cutlip DE, Popma JJ, Fitzgerald PJ, Williams DO, Heuer H, O’Shaughnessy CD, Overlie PA, Mann JT, Cannon LA, Hermiller JB, Henry TD, Whitbourn R, Thomas D. Stuckey TD, Midei MD, Coe J, Schwartz LB. A Randomized, Conrolled, Multi-center trial Comparing the Safety and Efficacy of Zotarolimus-Eluting and paclitaxil-eluting stents in de novo Occlusive lesions in the Coronary Arteries: Final Results of the ZoMaxx II Trial. Int J Cardiol. 2011 Jun 7.

69. Role of carotid stenting in management of carotid bifurcation disease: was the revolution overstated? Gray WA. Semin Vasc Surg. 2011 Mar;24(1):21-3.

70. Carotid stenting or carotid surgery in average surgical-risk patients: interpreting the conflicting clinical trial data. Gray WA. Prog Cardiovasc Dis. 2011 Jul-Aug;54(1):14-21.

71. Paclitaxel-iopromide coated balloon followed by "bail-out" bare metal stent in porcine iliofemoral arteries: first report on biological effects in peripheral circulation. Milewski K, Tellez A, Aboodi MS, Conditt GB, Yi GH, Thim T, Stenoien M, McGregor JC, Gray WA, Virmani R, Granada JF, Kaluza GL. EuroIntervention. 2011 Jul;7(3):362-8

72. Redo Thoracic Endovascular Aortic Repair Due to Endoleak With Celiac Artery Snorkeling. Planer D, Bliagos D, Gray WA. Ann Vasc Surg. 2011 Aug 10.

73. Gray WA. Carotid artery stenting before cardiac surgery a promising path down a muddy road? JACC Cardiovasc Interv. 2011 Nov;4(11):1197-9.

25

74. Matsumura JS, Gray W, Chaturvedi S, Yamanouchi D, Peng L, Verta P. Results of carotid artery stenting with distal embolic protection with improved systems: Protected Carotid Artery Stenting in Patients at High Risk for Carotid Endarterectomy (PROTECT) trial. J Vasc Surg. 2012 Jan 5.

75. Gray WA, Macdonald S, Schneider PA. Should Medicare reimbursement for carotid artery stenting be extended to standard and low risk symptomatic and asymptomatic patients with carotid stenosis? Vascular. 2012 Feb;20(1):7-11.

76. Smilowitz NR, Kirtane AJ, Guiry M, Gray WA, Dolcimascolo P, Querijero M, Echeverry C, Kalcheva N, Flores B, Singh VP, Rabbani L, Kodali S, Collins MB, Leon MB, Moses JW, Weisz G. Practices and complications of vascular closure devices and manual compression in patients undergoing elective transfemoral coronary procedures. Am J Cardiol. 2012 Jul 15;110(2):177-82.

77. Gray WA, Simonton CA, Verta P. Overview of the 2011 Food and Drug Administration Circulatory System Devices Panel meeting on the ACCULINK and ACCUNET Carotid Artery Stent System. Circulation. 2012 May 8;125(18):2256-64.

78. Vilain KR, Magnuson EA, Li H, Clark WM, Begg RJ, Sam AD 2nd, Sternbergh WC 3rd, Weaver FA, Gray WA, Voeks JH, Brott TG, Cohen DJ; Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk: results from the Carotid Revascularization Endarterectomy Versus Stenting Trial. Stroke. 2012 Sep;43(9):2408-16

79. Molnar RG, Gray WA. Sustained patency and clinical improvement following treatment of atherosclerotic iliac artery disease using the Assurant cobalt iliac balloon-expandable stent system. J Endovasc Ther. 2013 Feb;20(1):94-103.

80. Wayangankar SA, Abu-Fadel MS, Aronow HD, Kennedy KF, Gupta R, Yeh RW, Gray WA, Rosenfield K, Hennebry TA. Hemorrhagic and ischemic outcomes after bivalirudin versus unfractionated heparin during carotid artery stenting: a propensity score analysis from the NCDR. Circ Cardiovasc Interv. 2013 Apr;6(2):131-8.

81. Weisz G, Smilowitz NR, Parise H, Devaud J, Moussa I, Ramee S, Reisman M, White CJ, Gray WA. Objective simulator-based evaluation of carotid artery stenting proficiency. Am J Cardiol. 2013 Jul 15;112(2):299-306

82. Stilp E, Baird C, Gray WA, Schneider PA, Simonton CA, Verta P, Mena-Hurtado CI. An evidence-based review of the impact of periprocedural myocardial infarction in carotid revascularization. Catheter Cardiovasc Interv. 2013 Nov 1;82(5):709-14

83. Lim DS, Reynolds MR, Feldman T, Kar S, Herrmann HC, Wang A, Whitlow PL, Gray WA, Grayburn P, Mack MJ, Glower D. Improved Functional Status and Quality of Life in Prohibitive Surgical Risk Patients With Degenerative Mitral Regurgitation Following Transcatheter Mitral Valve Repair with the MitraClip® System. J Am Coll Cardiol. 2013 Oct 24. pii: S0735-1097(13)05864-6.

26

84. Gray WA, Verta P. The impact of regulatory approval and Medicare coverage on outcomes of carotid stenting. Catheter Cardiovasc Interv. 2013 Nov 9.

85. ACST-2 Collaborative Group, Halliday A, Bulbulia R, Gray W, Naughten A, den Hartog A, Delmestri A, Wallis C, le Conte S, Macdonald S. Status update and interim results from the asymptomatic carotid surgery trial-2 (ACST-2). Eur J Vasc Endovasc Surg. 2013 Nov;46(5):510-8.

86. Olin JW, Gornik HL, Bacharach JM, Biller J, Fine LJ, Gray BH, Gray WA, Gupta R, Hamburg NM, Katzen BT, Lookstein RA, Lumsden AB, Newburger JW, Rundek T, Sperati CJ, Stanley JC. Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association. Circulation. 2014 Mar 4;129(9):1048-78.

87. Downey P, Zalewski A, Takayama H, Kirtane A, Pucillo A, Gray W, Ali ZA.

Bilateral embolic protection devices for high-risk cardiac surgery in a patient with recent embolic stroke. Circ Cardiovasc Interv. 2014 Jun;7(3):414-6

88. Shishehbor MH, Venkatachalam S, Gray WA, Metzger C, Lal BK, Peng L, Omran HL, Blackstone EH. Experience and outcomes with carotid artery stenting: an analysis of the CHOICE study (Carotid Stenting for High Surgical-Risk Patients; Evaluating Outcomes Through the Collection of Clinical Evidence). JACC Cardiovasc Interv. 2014 Nov;7(11):1307-17

89. Gray WA, Feiring A, Cioppi M, Hibbard R, Gray B, Khatib Y, Jessup D, Bachinsky W, Rivera E, Tauth J, Patarca R, Massaro J, Stoll H-P, Jaff MR. S.M.A.R.T.™ Self-Expanding Nitinol Stent for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: One-Year Primary Outcomes of the STROLL Trial J Vasc Intern Radiol.2015 Jan;26(1): 21-8.

90. Gray WA, Mehta M, Alani F, Kasirajan K, Begg RJ, Bacharach JM, Soukas PA. Use of a Novel Embolic Filter in Carotid Artery Stenting: 30-Day Results from the EMBOLDEN Clinical Study (in review)

91. Mitsopoulos G, Hanna RF, Brejt SZ, Goldstein GE, Sheynzon V, Weitraub JL, Gray WA. Retrieval of a Dislodged Catheter Using Combined Fluoroscopy and Intracardiac Echocardiography. Case Reports in Radiology. 2015, Article ID 610362, 4 pages

92. Gray WA. Flights from wonder: the search for meaning in diffusion-weighted brain lesions. J Am Coll Cardiol. 2015 Feb 17;65(6):530-2.

93. Maehara A, Mintz GS, Shimshak TM, Ricotta JJ 2nd, Ramaiah V, Foster MT 3rd, Davis TP, Gray WA. Intravascular ultrasound evaluation of JETSTREAM atherectomy removal of superficial calcium in peripheral arteries. EuroIntervention. 2015 May;11(1):96-103

94. Patel MR, Conte MS, Cutlip DE, Dib N, Geraghty P, Gray W, Hiatt WR, Ho M, Ikeda K, Ikeno F, Jaff MR, Jones WS, Kawahara M, Lookstein RA, Mehran R,

27

Misra S, Norgren L, Olin JW, Povsic TJ, Rosenfield K, Rundback J, Shamoun F, Tcheng J, Tsai TT, Suzuki Y, Vranckx P, Wiechmann BN, White CJ, Yokoi H, Krucoff MW. Evaluation and treatment of patients with lower extremity peripheral artery disease: consensus definitions from Peripheral Academic Research Consortium (PARC). J Am Coll Cardiol. 2015 Mar 10;65(9):931-41

95. Crystal MA, Vincent JA, Gray WA. The wedding cake solution: A percutaneous correction of a form fruste superior sinus venosus atrial septal defect. Catheter Cardiovasc Interv. 2015 Dec 1;86(7):1204-10.

96. Sardar P, Chatterjee S, Giri J, Kundu A, Tandar A, Sen P, Nairooz R, Huston J, Ryan JJ, Bashir R, Parikh SA, White CJ, Meyers PM, Mukherjee D, Majersik JJ, Gray WA. Endovascular therapy for acute ischaemic stroke: a systematic review and meta-analysis of randomized trials. Eur Heart J. 2015 Sep 14;36(35):2373-80.

97. Yaghi S, Song C, Gray WA, Furie KL, Elkind MS, Kamel H. Left Atrial Appendage Function and Stroke Risk. Stroke. 2015 Dec;46(12):3554-9

98. Feldman T, Kar S, Elmariah S, Smart SC, Trento A, Siegel RJ, Apruzzese P, Fail P, Rinaldi MJ, Smalling RW, Hermiller JB, Heimansohn D, Gray WA, Grayburn PA, Mack MJ, Lim DS, Ailawadi G, Herrmann HC, Acker MA, Silvestry FE, Foster E, Wang A, Glower DD, Mauri L; EVEREST II Investigators.Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation: 5-Year Results of EVEREST II. J Am Coll Cardiol. 2015 Dec 29;66(25):2844-54.

99. Maertens H, Aggarwal R, Macdonald S, Vermassen F, Van Herzeele I; FOundER Group. Transatlantic Multispecialty Consensus on Fundamental Endovascular Skills: Results of a Delphi Consensus Study. Eur J Vasc Endovasc Surg. 2016 Jan;51(1)

100. Costa RA, Abizaid A, Mehran R, Schofer J, Schuler GC, Hauptmann KE, Magalhães MA, Parise H, Grube E; BioFreedom FIM Clinical Trial Investigators. Polymer-Free Biolimus A9-Coated Stents in the Treatment of De Novo Coronary Lesions: 4- and 12-Month Angiographic Follow-Up and Final 5-Year Clinical Outcomes of the Prospective, Multicenter BioFreedom FIM Clinical Trial. JACC Cardiovasc Interv. 2016 Jan 11;9(1)

101. Aronow HD, Collins TJ, Gray WA, Jaff MR, Kluck BW, Patel RA, Rosenfield KA, Safian RD, Sobieszczyk PS, Wayangankar SA, White CJ. SCAI/SVM expert consensus statement on carotid stenting: Training and credentialing for carotid stenting. Catheter Cardiovasc Interv. 2016 Feb 1;87(2):188-99.

102. Brott TG, Howard G, Roubin GS, Meschia JF, Mackey A, Brooks W, Moore WS, Hill MD, Mantese VA, Clark WM, Timaran CH, Heck D, Leimgruber PP, Sheffet AJ, Howard VJ, Chaturvedi S, Lal BK, Voeks JH, Hobson RW 2nd; CREST Investigators. Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis. N Engl J Med. 2016 Mar 17;374(11):1021-31.

103. Rosenfield K, Matsumura JS, Chaturvedi S, Riles T, Ansel GM, Metzger DC, Wechsler L, Jaff MR, Gray W; ACT I Investigators. Randomized Trial of

28

Stent versus Surgery for Asymptomatic Carotid Stenosis. N Engl J Med. 2016 Mar 17;374(11):1011-20

104. Adams GL, Mustapha J, Gray W, Hargus NJ, Martinsen BJ, Ansel G, Jaff MR. The LIBERTY study: Design of a prospective, observational, multicenter trial to evaluate the acute and long-term clinical and economic outcomes of real-world endovascular device interventions in treating peripheral artery disease. Am Heart J. 2016 Apr;174:14-21.

105. Eudailey K, Hamid N, Hahn RT, Kodali S, Gray W, George I. Mitraclip Followed by Surgical Aortic Valve Replacement: Hybride Techniques for Regurgitant Aortic and Mitral Valve Disease. Ann Thorac Surg. 2016 Aug;102(2)

106. Kadian-Dodov D, Gornik HL, Gu X, Froehlich J, Bacharach JM, Chi YW,

Gray BH, Jaff MR, Kim ES, Mace P, Sharma A, Kline-Rogers E, White C, Olin JW. Dissection and Aneurysm in Patients With Fibromusclar Dysplasia: Findings From the U.S. Registry for FMD. J Am Coll Cardiol. 2016 Jul 12;68(2):176-85

107. Pavo N, Samaha E, Sabdyusheva I, von Strandmann RP, Stahnke S, Plass CA, Zlabinger K, Lukovic D, Jambrik Z, Pavo IJ, Bergler-Klein J, Gray WA, Maurer G, Gyongyosi M. Coating of intravascular balloon with paclitaxel prevents constrictive remodeling of the dilated porcine femoral artery due to inhibition of intimal and media fibrosis. J Mater Sci Mater Med. 2016 Aug;27(8):131.

108. Eudailey K, Hamid N, Hahn RT, Kodali S, Gray W George I. Mitraclip Followed by Surgical Aortic Valve replacement: Hybrid Techniques for Regurgitant Aortic and Mitral valve Disease. Ann Thorac Surg. 2016 Aug;102(2):e83-5.

109. Cheng Y, Shibuya M, McGregor J, Conditt GB, Yi GH, Kaluza GL, Gray

W, Doshi M, Sojitra P, Granada JF. Biological effect on restenosis and vascular healing of encapsulated paclitaxel nancrystals deliverd via coated balloon technology in the familial hypercholesterolaemic swine model of in-stent restenosis. EuroIntervention. 2016 Oct 20;12(9):1164-1173

110. Omran J, Mahmud E, White CJ, Aronow HD, Drachman DE, Gray W, Abdullah O, Abu-Fadel M, Firwana B, Mishkel G, AL-Dadah AS. Proximal balloon occlusion versus distal filter protection in carotid artery stenting: A meta-analysis and review of the literature. Catheter Cardiovasc Interv. 2016 Nov 12.

111. Omran J, Abdullah O, Abu-Fadel M, Gray A, Firwana B, Drachman DE, Mahmud E, Aronow HD, White CJ, Al-Dadah AS. Hemorrhagic and ischemic outcomes of Heparin vs Bivalirudin in carotid artery stenting: A met-analysis of studies. Catheter Cardiovasc Interv. 2017 Mar 1;89(4):746-753.

112. Pelberg J, Gray WA. Good to great: TAVR tackles stroke risk. Catheter Cardiovasc Interv. 2017 Feb 15;89(3):478-479

113. Ahmad S, Gray WA. Closing the gap. Catheter Cardiovasc Interv. 2017 Mar 1;89(4):773-774.

29

Reviews, Chapters and Editorials

1. Gray WA. The "Nearly Successful" Resuscitation. Lancet. 1993 Apr 3;341(8849):866

2. Gray WA. A cardiologist in the carotids. J Am Coll Cardiol. 2004 May 5;43(9):1602-1605. Review.

3. Gray WA. Endovascular treatment of extra-cranial carotid artery bifurcation disease. Minerva Cardioangiol. 2005 Feb;53(1):69-77. Review.

4. Gray WA. Cervical carotid revascularization: indications from an endovascular perspective. Neurosurg Clin N Am. 2005 Apr;16(2):259-61, viii. Review.

5. Gray WA, Management of Asymptomatic Carotid Artery Disease. Chapter in Asymptomatic Carotid Artery Stenosis: Risk Stratification and Management, 1st Editon. Issam Moussa, Tanya Rundek, and Jay Preston Mohr. 256 pp, Informa Healthcare, 2007

6. Gray WA. Clinical trials: past, present, and future. Semin Vasc Surg. 2008 Jun;21(2): 80-7. Review.

7. The Differences in United States and European Union Randomized Carotid Artery Stent vs. Endarterectomy Trial Design Explain the Disparate Trial Outcomes. Charing Cross 33. Greenhalgh R. 2011

8. How to interpret critical reviews of randomized studies and registries. The Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Henry M, Dietrich EB and Polydorou A. 2011. 2nd ed.

9. Carotid stenting or carotid surgery in average-surgical risk patients: Interpreting the conflicting clinical trial data. Progress in Cardiovascular Disease Prog Cardiovasc Dis. 2011 Jul-Aug;54(1):14-21.

10. Drug Coated Balloons for Vascular Restenosis. Topol’s 6th Edition Textbook of Interventional Cardiology 2011.

11. Endovascular Therapies: Carotid Bifurcation. Abrams’ Angiography: Interventional Radiology, 3rd edition 2013

12. Goyal NK, Gray WA, Chronic Total Occlusions in peripheral arterial disease. Chapter (In Press)

13. Abizaid A, Yeung A, Gray WA, Chevalier B, Meredith I, Stone GW, Schwartz LB. The ZoMaxx Zotarolimus-Eluting Coronary Stent: Rationale, Experimental Results and Clinical Trials. Chapter (In Press)

14. Gray WA. Carotid artery stenting. Braunwald Intervention (in preparation)

15. Kapur V, Gray WA, Management of Aneurysmal Disease of the Aorta. Interventional Cardiology Clinics; Peripheral Vascular Disease. Oct 2014.

30

Books

1. Cissarek T, Gray W, Kroger K, Zeller T. Vascular Medicine and Intervention.

2010 (1st Edition) 2014 (2nd Edition)