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Wait-and-See Policy as a First-Line Management for Extra-Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur, Frédérique Larousserie, Philippe Anract, and François Gouin J Bone Joint Surg Am Volume 96(8):631-638 April 16, 2014 ©2014 by The Journal of Bone and Joint Surgery, Inc.

Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

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Cumulative probability of the patient dropping out from the wait-and-see policy (left axis) by time (bottom axis), estimated in a competing-risk setting. Sylvain Briand et al. J Bone Joint Surg Am 2014;96: ©2014 by The Journal of Bone and Joint Surgery, Inc.

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Page 1: Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

Wait-and-See Policy as a First-Line Management for Extra-Abdominal Desmoid Tumors

by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur, Frédérique Larousserie, Philippe Anract, and François Gouin

J Bone Joint Surg AmVolume 96(8):631-638

April 16, 2014

©2014 by The Journal of Bone and Joint Surgery, Inc.

Page 2: Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

Process for the selection of the patients for the study and their management.

Sylvain Briand et al. J Bone Joint Surg Am 2014;96:631-638

©2014 by The Journal of Bone and Joint Surgery, Inc.

Page 3: Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

Cumulative probability of the patient dropping out from the wait-and-see policy (left axis) by time (bottom axis), estimated in a competing-risk setting.

Sylvain Briand et al. J Bone Joint Surg Am 2014;96:631-638

©2014 by The Journal of Bone and Joint Surgery, Inc.

Page 4: Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

Proportion of patients with a nonprogressive tumor (left axis), with 95% confidence intervals, after different periods of time (bottom axis).

Sylvain Briand et al. J Bone Joint Surg Am 2014;96:631-638

©2014 by The Journal of Bone and Joint Surgery, Inc.

Page 5: Wait-and-See Policy as a First-Line Management for Extra- Abdominal Desmoid Tumors by Sylvain Briand, Olivier Barbier, David Biau, Axelle Bertrand-Vasseur,

Radiographic evolution of tumor size over time represented by the ratio of the actual tumor size to the initial size for primary (Fig. 4-A) and recurrent (Fig. 4-B) tumors and by the real size (Fig. 4-

C) for patients who dropped out from the wait-and-see po...

Sylvain Briand et al. J Bone Joint Surg Am 2014;96:631-638

©2014 by The Journal of Bone and Joint Surgery, Inc.