Version 1.0 | AUG 2018 Access

SPC-ADRS-1.0© 2018 LABCYTE INC. All rights reserved.

Access™DUAL ROBOT SYSTEMFOR ACOUSTIC SAMPLE MANAGEMENT

TECHNICAL SPECIFICATIONS Version 1.0 | AUG 2018

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Table of Contents

TECHNICAL SPECIFICATIONS Access™ Dual Robot System

Access™ Dual Robot System (DRS) for Sample Management, Ultra High Throughput Assay-Ready Plate Creation System ............................... 3

Access™ Dual Robot System (DRS) for Sample Management, High Throughput Assay-Ready Cell Plate Creation System .................................4

System Device Specifications .......................................................................................................................................................................................................................... 5

System Module Types ......................................................................................................................................................................................................................................... 9

Dual Robot Module ...................................................................................................................................................................................................................................... 9

Device Module #1 ........................................................................................................................................................................................................................................ 10

Device Module #2 .........................................................................................................................................................................................................................................11

Echo Module ..................................................................................................................................................................................................................................................12

Ambient Storage Module .........................................................................................................................................................................................................................12

MicroServe Module .....................................................................................................................................................................................................................................13

Incubator Storage Module .......................................................................................................................................................................................................................13

System Dimensions .............................................................................................................................................................................................................................................14

System Weight ......................................................................................................................................................................................................................................................15

System Configuration .......................................................................................................................................................................................................................................16

Environment HVAC Integration and Distribution .......................................................................................................................................................................... 17

Automated Docking ..................................................................................................................................................................................................................................18

Echo Turntable ............................................................................................................................................................................................................................................18

Slide-Out Shelves .......................................................................................................................................................................................................................................19

System Performance ........................................................................................................................................................................................................................................ 20

System Workflow....................................................................................................................................................................................................................................... 20

Access System Process Step Timings ............................................................................................................................................................................................... 20

System Throughput ....................................................................................................................................................................................................................................21

System Capacities .......................................................................................................................................................................................................................................21

Additional System Options .............................................................................................................................................................................................................................22

Computer Specifications and Supported Operating System ..........................................................................................................................................................23

Supported Software Versions ........................................................................................................................................................................................................................23

Supported Labware ............................................................................................................................................................................................................................................23

Additional Supported Devices ......................................................................................................................................................................................................................24

Supported Accessories and Specifications .............................................................................................................................................................................................25

System Requirements .......................................................................................................................................................................................................................................26

Power Requirements .................................................................................................................................................................................................................................26

Air Requirements ........................................................................................................................................................................................................................................26

Vacuum Requirements .............................................................................................................................................................................................................................26

Laboratory Floor Requirements ...........................................................................................................................................................................................................26

Laboratory Environment Requirement ..............................................................................................................................................................................................27

Building Management System (BMS) .................................................................................................................................................................................................27

System Certification and Compliance Standards .................................................................................................................................................................................27

SPC-ADRS-1.0 3

Access™ Dual Robot System (DRS) for Sample Management, Ultra High Throughput Assay-ready Plate Creation System

LABCYTE INC.

Legend Device Name Manufacturer Device Type Quantity

A Echo 655T Labcyte Acoustic Liquid Handler 2

B PF750 Robot Precise Automation Microplate Handler 2

C IntelliXCap Brooks Life Sciences Capper/Decapper 4

D HiG 3 BioNex Solutions Centrifuge 2

E Microplate Labeler (VCode) Agilent Technologies Microplate Labeler 1

F PlateLoc Agilent Technologies Heat Sealer 2

G XPeel Brooks Life Sciences Seal Remover 1

H Certus Flex Fritz Gyger AG Nanoliter Bulk Dispenser 1

I AmbiStore M HighRes Biosolutions High-capacity Random-access Storage 1

J MicroServe HighRes Biosolutions High-capacity FILO Stacker 1

K Random-access Hotels Labcyte 20-position Temporary Hotels 4

L 10-position Delidder Labcyte Lid/De-Lid Station 1

M Barcode Reader Labcyte 1D/2D Keyence Barcode Reader 1

N Regrip Nest Labcyte Regrip from Portrait to Landscape 1

O Hand over Nests Labcyte Transfer between Robots 1

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C

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HA I

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AGE

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RIGHT VIEW

LEFT VIEW

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Access™ Dual Robot System (DRS) for Sample Management, High Throughput Assay-ready Cell Plate Creation System


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F

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D

A

J

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JA

D

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F

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Legend Device Name Manufacturer Device Type Quantity

A Echo 655T Labcyte Acoustic Liquid Handler 2

B PF750 Robot Precise Automation Microplate Handler 2

C IntelliXCap Brooks Life Sciences Capper/Decapper 4

D HiG 3 BioNex Centrifuge 2

E Microplate Labeler (VCode) Agilent Technologies Microplate Labeler 1

F PlateLoc Agilent Technologies Heat Sealer 2

G XPeel Brooks Life Sciences Seal Remover 1

H Certus Flex Fritz Gyger AG Nanoliter Bulk Dispenser 1

I AmbiStore M HighRes Biosolutions High-capacity Random-access Storage 1

J Cytomat 10C Thermo Fisher Scientific High-capacity Incubator Storage 1

K Random-access Hotels Labcyte 20-position Temporary Hotels 4

L 10-position Delidder Labcyte Lid/De-Lid Station 1

M Barcode Reader Labcyte 1D/2D Keyence Barcode Reader 1

N Regrip Nest Labcyte Regrip from Portrait to Landscape 1

O Hand over Nests Labcyte Transfer between Robots 1

RIGHT VIEW

LEFT VIEW

SPC-ADRS-1.0 5

System Device Specifications

Labcyte Echo® 655T Acoustic Liquid Handler

Description Acoustic liquid handler that supports acoustic tubes and plates

Drop volume 2.5 nL

Volume transfer range 2.5 to 5,000 nL(the range is dependent on the fluid type, assay, and source plate used)

Transfer accuracy < 10% deviation from target volume

Transfer precision < 8% CV

Source labware compatibility

Echo® Qualified Tubes, 384- and 1536-well microplates

Destination labware compatibility

All Echo Qualified Microplates, 96- acoustic tube racks and most ANSI-compliant/SLAS-standard microplates in 96-, 384-, 1536-, and 3456-well formats with 8 to 16 mm well height

For more specifications

www.labcyte.com/support/specification-sheets

Precise PF750

Precise PF750 Microplate handling robot

Drive 4-axis, servo controlled, absolute encoders

Max horizontal reach 576 mm

Vertical reach 750 mm

Maximum velocity 500 mm/sec

Maximum acceleration

2500 mm/sec 2

Repeatability ± 50 μm

Payload 500 gm

Gripper Servo

Brooks Life Sciences IntelliXCap™ Decapper

Description Acoustic tube compatible 96 channel capper/decapper

Speed Whole or partial rack cap/decap in 20–30 secs

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Agilent Microplate Labeler

Description Microplate barcode labeler with a wide range of formats and optional barcode reader

Cycle time 4 seconds per label

Symbologies Code 128, Code 39 (full ASCII), Interleaved 2 of 5, Codabar, Code 93, HIBC, Data Matrix (2D), PDF 417 (2D), Micro PDF 417 (2D)

Label dimensions Standard size = 50.8 mm W x 6.35 mm H [2 in x 0.25 in], smaller sizes available

Roll length 6,500 or 13,000 labels per roll

Supported labware Microplates that meet the ANSI Standards, ANSI/SLAS 1-2004 through ANSI/SLAS 4-2004

Agilent PlateLoc Sealer

Description Microplate heat sealer, with Labcyte customized universal plate insert and gas purging option available

Supported labware Microplates up to 51 mm (2 in) tall

Cycle time Approximately 8 seconds per plate

Warm-up Time 2.5 minutes

Cool-down Time 1 hour (from 160°C to room temperature)

Sealing temperature 30 to 200°C

Seal types [Plates per roll]

Peelable Aluminum [5,000], Peelable Aluminum RT* [5,000], Pierceable Aluminum [5,000], Clear Peelable [2,000], Clear Pierceable [4,700], Clear Permanent [5,000]* NOTE: Contact Agilent for labware and seal type compatibility

BioNex HiG™ 3 Centrifuge

Description High speed, high imbalance tolerance microplate centrifuge speed; Up to 5000 x G, acceleration/deceleration in 20 s; Insert required for high speeds

Imbalance tolerance Up to 100-gram weight difference between buckets.

Supported labware ANSI/SLAS microplates up to 61 mm in height


SPC-ADRS-1.0 7

HighRes Biosolutions AmbiStore™ M

Description High-capacity, random-access, ambient storage device

Number of hotels 28 with variety of choices based on labware thickness

Hotel specifications • 33 – Position // 11.1 mm max height (including lid)

• 24 – Position // 17.3 mm max height (including lid)

*Hotel type used in Access DRS system*

• 10 – Position // 49.4 mm max height (including lid)

Capacity(assumes unit is all one hotel type)

672, acoustic tube racks or 96-, or 384-well plates; 924, 1536-well plates; 280 deep-well plates

Speed 10–12 s retrieval/storage time

Input/output 2 nests to maximize input/output retrieval times (up to 6 can be configured)

Barcode reader Integrated Microscan MS-3 Barcode Scanner

Fritz Gyger AG Certus Flex

Description Contact-less nanoliter bulk dispenser

Dispense technology 5 or 8 individual Micro valves

Volume range 50 nL – 1000 uL

Accuracy > 500 nL ± 1.5 %

Precision < 100 nL, CV < 5 % // > 100nL CV < 2 %

Speed 384-wells – 47 s (Single Channel) / 13 s (4 Channel); 1536-wells - 145 s (Single) / 39 s (4 Channel)

Supported labware ANSI/SLAS 48-, 96-, 384-, 1536-, 3456-well plates 3 – 51 mm in height

Supported reagents 1 to 8 reagent types including DMSO, aqueous buffers, alcohols, cells, proteins or oils*Contact Fritz Gyger AG for more info

Brooks Life Sciences XPeel® Automated Microplate Seal Removal

Description Adhesive tape microplate seal remover

Tape roll capacity Up to 400 plates

Speed Up to 200 plates per hour

LABCYTE INC.

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Thermo Scientific™ Cytomat™ 10C Incubator

Description Environment controlled incubator, storage device

Unload/load speed 10 s

Temperature Ambient +10°C to 50°C

Humidity Humidity up to 98% RH at 37°C

CO2 CO2 range of 0–20 Vol. %

Number of hotels 10 with variety of choices based on labware thickness

Autoclavable hotel specifications

• 28-Postion: Max height 12 mm (including lids)



• 10-Position: Max height 45 mm (including lids)

Capacity 260 – 280, 1536-well plates ; 210, acoustic tube racks and 96-, or 384-well plates; 100, deep-well plates

HighRes Biosolutions MicroServe™ Labware Stacker

Description High-capacity, random-access, ambient storage device

Number of stacker positions

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Capacity 1120, 1536-well plates ; 770, 96- or 384-well plates; 154 deep-well plates

Barcode reader Integrated Microscan MS-3 Barcode Scanner


SPC-ADRS-1.0 9

DUAL ROBOT MODULE

• Integrated with 6 modules

- 2 Device Modules, 2 Storage Modules, 2 Echo Systems

• Configured with 2x PF750, but can also support 2x PF1160 or mix of 1x PF750 and 1x PF1160 robots

• Configured to supports up to 4 automated docking modules (optional)

Dual Robot Module Weight

• Robot module total: 1858 lb; 843 kg

Weight includes core components, devices, accessories, and both docking and environment features.

System Module Types

FRONT VIEW

TOP VIEW

LABCYTE INC.

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DEVICE MODULE #1


• Includes XPeel, Microplate Labeler, HiG 3, PlateLoc

• Supports integration of alternative devices listed in “Supported Devices”

• Equipped with automated docking and environment features (optional)

• Configurable to include 1 – 3 shelves of different type

- Slide out (Top Shelf with XPeel and Labeler)

- Fixed (Middle Shelf with HiG and PlateLoc)

- Turntable (not shown)

84in2133mm

HiG3 NEST

41in1043mm

38in

PLATELOC NEST

1585mm62in

1434mm

XPEEL NEST

56in

969mm

34in876mm

64in1634mm

VCODE NEST

40in1004mm

36in927mm

84in2133mm

HiG3 NEST

41in1043mm

38in

PLATELOC NEST

1585mm62in

1434mm

XPEEL NEST

56in

969mm

34in876mm

64in1634mm

VCODE NEST

40in1004mm

36in927mm

84in2133mm

HiG3 NEST

41in1043mm

38in

PLATELOC NEST

1585mm62in

1434mm

XPEEL NEST

56in

969mm

34in876mm

64in1634mm

VCODE NEST

40in1004mm

36in927mm

FRONT VIEW

TOP VIEW

Device Module #1 Weight



SPC-ADRS-1.0 11

DEVICE MODULE #2

• Includes Certus, HiG 3, PlateLoc

• Supports integration of alternative devices listed in “Supported Devices”

• Is equipped with automated docking and environment features

• Configurable to include 1 – 3 shelves of different type

- Slide Out (Top Shelf with Certus)

- Fixed (Middle Shelf with HiG and PlateLoc)

- Turntable (not shown)

• Option for Ergotron and monitor mount

LABCYTE INC.

FRONT VIEW TOP VIEW

84in2134mm

1434mm56in

38in969mm

34in876mm

38in971mm

60in1530mm

40in1004mm

36in927mm

Device Module #2 Weight



12

471191

ECHO NEST

[FOR REFERENCE ONLY]

CUSTOMER:

LAYOUT OPTION

UNCONTROLLED

PROPRIETARY AND CONFIDENTIAL

18

896

465

35

20517

INTELLICAP NEST

35894

401004

AMBIENT STORAGE MODULE

471191

ECHO NEST

[FOR REFERENCE ONLY]

CUSTOMER:

LAYOUT OPTION

UNCONTROLLED

PROPRIETARY AND CONFIDENTIAL

18

896

465

35

20517

INTELLICAP NEST

35894

401004

ECHO MODULE

• Integrated with Echo® 655T Liquid Handler (also supported 5XX models) and relative accessories

• Equipped with automated docking (optional)

• Configured with Echo turntable (optional)

• Includes slide out shelf underneath with 2x, IntelliXCaps

- Other options include Fixed or Turntable shelf

• Option for Ergotron and monitor mount

• Integrates and provides an enclosure for ambient storage devices such as HighRes AmbiStore D & M models, HighRes MicroServe and NanoServe Models, Thermo Cytomat Hotel models, and Liconic LPX models.

• Automated docking option available.

• Computer, Ergotron and Monitor are mounted to this module

FRONT VIEW


84in2134mm

927mm36in

36in911mm

11in270mm

70in1772mm

84in2134mm

927mm36in

36in911mm

11in270mm

70in1772mm

FRONT VIEW

TOP VIEW

TOP VIEW

Storage Module Weight

• AmbiStore + module total: 827 lb; 375 kg

Weight includes core components, devices, and accessories. This module is fixed and not equipped with docking or environment features.

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LABCYTE INC.

STORAGE MODULE WITH MICROSERVE

36in915mm

36in905mm

70in1787mm

876mm34in

44in1129mm

CYTOMAT NEST

36in915mm

36in905mm

70in1787mm

876mm34in

44in1129mm

CYTOMAT NEST

FRONT VIEW

TOP VIEW

842133

13

481208

332

561415

37927

36911

842133

13

481208

332

561415

37927

36911

FRONT VIEW

TOP VIEW

INCUBATOR STORAGE MODULE

• Integrates storage devices that have their own safety or environment enclosure.

• Automated docking option available, but not on this system

• Option for Ergotron and Monitor mount


• MicroServe + module total: 575 lb; 261 kg



• Cytomat + module total: 642 lb; 291 kg


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System Dimensions

NOTE: Additional 1 meter clearance needed around system for doors and docking.

39in1000mm

SERVICE AREA

39in1000mm

SERVICE AREA

39in1000mm

SERVICE AREA39in1000mm

SERVICE AREA

221in5603mm

SERVICE AREA

193in4901mm

SERVICE AREA

36in922mm

FOOTPRINTSYSTEM2901mm

114in

FOOTPRINTSYSTEM3603mm

142in

892mm35in

988mm39in

71in1814mm

TOP VIEW


SPC-ADRS-1.0 15


• uHT ARP system total: 7072 lb; 3209 kg

• Cell ARP system total: 7139 lb; 3239 kg

Weight includes all modules, core components, docking, and environment features.

LABCYTE INC.

SIDE VIEWS

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System Configuration

The Access DRS for Cell and Standard Assay-ready Plate creation layout consists of the following modules and options.

AUTOMATED DOCKING

AUTOMATED DOCKING

ECHO MODULE

ECHO MODULE

DEVICE MODULE #1

DEVICE MODULE #2

STORAGE MODULE[AMBISTORE]

STORAGE MODULE[MICROSERVE OR

CYTOMAT]

HVAC ENVIRONMENTINTEGRATION/DISTRIBUTION


SPC-ADRS-1.0 17

LABCYTE INC.

To maintain a low %RH environment inside the processing area, the system has been designed to connect to and distribute conditioned air that is

provided by an external laboratory HVAC unit.

To meet the specifications the supplied air must

meet the following requirements.

• 20°C ± 1°C• 10% ± 2% RH• 350 – 500 CFM (total)

• 22°C ± 2°C• 10 - 50% RH

• 6 input HVAC connections- 2 Echo- 2 Device Module- 2 Robot Module

• 2 output HVAC connections- 2 Robot Module

System Internal Environment Specification

• Temperature: 24°C ± 2°C• Relative humidity: 10 – 15%

Connection Requirements

HVAC Air Input Requirements

Ambient Environment Requirements

Connection and Flow Rate Requirements Per Module

Environment HVAC Integration and Distribution

Tube Size Flow Rate Category

Legend In. mm Min. Max. Input/Output

A 6 150 100 CFM 145 CFM Input

B 6 150 -50 Pa -100 Pa Output

C 3 75 50 CFM 75 CFM Input

D 3 75 25 CFM 30 CFM Input

NOTE: See Site Prep Guide for more details.

D

C

B

C

A

B

D

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The Access systems are configured with 4 automated docking modules to provide easy access into the system without terminating a run in

progress.

Each Echo® Module is installed with an Echo® Turntable to allow standalone use and provide easy accessibility for maintenance.

• Locking, latch mechanism

• Up to 180-degree rotation with locking positions to enable standalone use

• Clean routing and management of HVAC (optional), chiller and vacuum tubing

• Integrated presence sensors

• Repeatable robot position: no reteaching required

Automated Docking Details

• Push button automated docking mechanism

• No re-teaching required

• 1 meter retractable umbilicus containing power, communication and utilities

• Integrated sensors to detect module presence

• Undock timing: 30s

• Dock timing: 30s

• Requires robot module to be bolted to floor See Site Prep Guide for details.

• Safety alarm option

Turntable Specifications

Repeatability Specifications

• ± 100 μm in X and Y, ± 200 μm in Z

AUTOMATED DOCKING

ECHO TURNTABLE


SPC-ADRS-1.0 19

LABCYTE INC.

The Access systems are equipped with slide-out shelves to provide access to devices that require frequent changing of consumables.

Shelf Specifications

• Max load: 196 kg / 432 lb

• Max extension: 1070 mm / 42 in

• Dual latch and slide rail mechanism

• Integrated sensors to detect shelf status

Example Shelf Dimensions

SLIDE-OUT SHELVES

ECHO MODULE

DEVICE MODULE

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New technologies from Labcyte, Titian Software, and Brooks Life Sciences have been integrated to produce a fully automated solution for acoustic

sample management workflow. The figure below highlights the entire process from order entry to Assay-ready Plate (ARP) creation.

System Performance

Action Timing

Unload and load from storage 12 - 14 s

Centrifuge (20 s spin @ 3000 RPM) 1 min 3 s

Decap tubes 24 s

Unseal plate 15 s

Seal plates (2.5 s seal apply time) 10 s

Cap tubes 36 s

Label plates (1 side) 8 s

Robot moves 12 - 20 s**

Action Plate

Echo dispense Variable*

Backfill dispense Variable*

*Varies due to number of wells and volume dispensed

**Accounts for variability caused by regrips and cross zone plate transfers

SYSTEM WORKFLOW

ACCESS SYSTEM PROCESS STEP TIMINGS

Submit Sample Order

Pick and Rack Tubes

Load Access Dual Robot Systemand Start Run

Upload Process Data

Upload Access System

Archive Tubesand Racks

Unload Labware from Storage

Devices

Centrifuge Tube Racks, Source or

Control Plates

Load Source and Destination

Labware into Echo System

Decap Tubes or Unseal Source

Apply Human Readable Label with Order Info

Seal Destinations Load Labware to Storage Device

Cap Tubes or Seal Source, Control or

Intermediate Plates

Dispense Samples Dispense ControlsBackfill

Intermediate

* For Dose-Response or Single Dilution protocols only. Backfill can be done either by Echo System or intergrated bulk dispenser.

*

SPC-ADRS-1.0 21

LABCYTE INC.

Table below details example throughput data for a series ARP creation support for different screening scenarios. This information takes in account

all the steps highlighted in the system workflow and process timing section.

Additional throughput data can be tested and provided on request.

SourceFormat

# ofSample/ Source

Int. Format

Det.Format

# ofReplicates

# of Dil.Points

EchoTransfer

Vol

#Samples/ Dest

# ofControls/ Dest

Total # of Samples

and Controls

Processed/Hour

DestPlates /

Hour

DestPlate /

Day

SCR

EE

N T

YP

E

Primary Screen 96 TR 88 N/A 1536 1 1 40 nL 1408 128 3614 2.4 19

Primary Screen 96 TR 88 N/A 384 1 1 40 nL 352 32 2836 7.4 60

Primary Screen 1536 1408 N/A 384 1 1 40 nL 352 0 10560 30.0 240

Primary Screen 1536 1408 N/A 1536 1 1 40 nL 1408 0 22528 16.0 128

Primary Screenwith Dilution

96 TR 88 384 PP 384 1 1 40 nL 352 32 3124 8.1 66

Primary Screenwith Dilution

96 TR 88 1536 LDV

1536 1 1 40 nL 1408 128 2671 1.7 14

Dose Response 96 TR 75 384 PP 384 4 10 50 nL 36 12 816 /(612 curves)

17.0 136

Dose Response 96 TR 75 384 PP 1536 4 10 50 nL 150 36 1116 / (900 curves)

6.0 48

Confirmation 96 TR 88 384 PP 384 4 1 50 nL 32 32 3686 9.6 77

Confirmation 96 TR 88 1536 LDV

1536 4 1 50 nL 1408 128 4757 3.1 25

SYSTEM THROUGHPUT

SYSTEM CAPACITIES

Ultra-High Throughput Assay-ready Plate Creation System

Cell Assay-ready Plate Creation System

Device # of Hotels # of Positions/Hotel Total Number Acoustic Tube Racks or Plates Notes

AmbiStore M 28 24 672 Random-access

MicroServe 14 N/A 770 (tubes or 96/384w plates) 1120 (1536 or 384 LDV plates)

FILO Stacker

Temporary Hotels 4 20 80 Robot Module

Device # of Hotels # of Positions/Hotel Total Number Acoustic Tube Racks or Plates Notes

AmbiStore M 28 24 672 Random-access

Cytomat 10C 10 21 210 FILO Stacker

Temporary Hotels 4 20 80 Robot Module

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Turntable for devices • Up to 180-degree rotation with locking positions to enable standalone use• Integrated presence sensors• Repeatable robot position: no reteaching required

Environment options Ambient and safety enclosure only• Integrated fans to vacate system heat from inside the system

HEPA Filter Fan• Adjustable fan speed• Snap-in prefilter allows for easy replacement and maintenance• High Efficiency Particulate Air Filter: 99.99% efficient @ 0.3 Micron

UPS option • Uninterrupted power supplies can be installed in each module; size and power output of UPS varies based on requirements

Building management system option

The Access Sample Management systems provide the option to connect and communicate to lab building management systems (BMS).This enables the following functionality and features:• Install environment probe/monitor to provide feedback of system environment conditions to lab HVAC/BMS to allow BMS to adjust system

input air to meet desired conditions• Automated system reaction to BMS feedback in the event of HVAC failure.

- Tempo flags plates and continues run.• Automated system response to BMS feedback in the event of lab power failure.

- If system has been running on generator power for a user specified amount of time, Tempo will stop run -> cap all tubes -> return to storage -> suspend any other runs from starting.

Blanking panels • Panels that install in place of a removed module, to allow for the system to operate while maintaining safety and the internal environment

Secondary containment • Drip drays and waste management options for bulk dispensing devices that use reagent bottles and priming reservoirs

Additional System Options


SPC-ADRS-1.0 23

Supported Software Versions

Supported Labware

• Tempo™ Automation Control Software: v 2.0 or greater

• Echo® Dose-Response: v 1.7.x or greater

• Echo® Combination Screening: v 1.7.x or greater

• Echo® Cherry Pick: v 1.7.x or greater

• Echo® Plate Reformat: v 1.7.x or greater

• Echo® Plate Audit v 1.7.x or greater

• Integration with Titian’s Mosaic Sample Software 7.0 or greater using Titian’s Tempo Fulfillment Module (TFM)

• All Echo® Qualified microplates, acoustic tubes and most ANSI-compliant/SLAS-standard microplates in 96-, 384-, 1536-, and 3456-well formats

8 to 16 mm total height without lid

• Automation compatible, low profile or Labcyte MicroClime Lids

• See random access hotel specifications under “Supported Accessories” for maximum labware height allowed with lid

• For Labcyte Echo Qualified Labware specifications, please reference www.labcyte.com/support/specification-sheets

Computer Specifications and Supported Operating System

• Intel® Core™ i7 -6500U, 2.5GHz

• Memory 16GB (up to 32GB possible)

• Storage 1x M.2 PCIe/SATA + 1x 2.5" SATA

• Disk Samsung 960PRO 512GB PCIe NVMe M.2 Internal SSD

• Graphics Intel® HD Graphics 520

• Ethernet 2x 10/100/1000 Mbps

• USB 2x USB 3.0 + 2x USB 3.1 (one USB Type-C)

• Monitor Dell 23" Monitor

• Dimensions 46.8 mm x 112.6 mm x 119.4 mm

• Windows 10 Operating System

LABCYTE INC.

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PF1160 Microplate Handling Robot

Drive 4-axis, servo controlled, absolute encoders

Max horizontal reach 576 mm

Vertical reach 1160 mm

Maximum velocity 500 mm/sec

Maximum acceleration 2500 mm/sec2

Repeatability ± 50 µm

Payload 500 gm

Gripper Servo

Liquid Handling

Labcyte Echo 5XX Liquid Handler Series

Labcyte Echo 65XT Liquid Handler Series

Plate Washing

BioTek EL406 washer

Real-time qPCR

Roche LightCycler 1536, 480

Multimode Reading

PerkinElmer EnVision Reader

BMG PHERAstar, ClarioStar, and Omega Series

Plate Shaker

Teleshake 1536

Thermal Cycler

Inheco ODTC 96, 384

Labeler

Agilent Microplate Labeler (VCode)

Seal Remover

Brooks XPeel

Centrifuge

Agilent Microplate Centrifuge (VSpin)

BioNex HiG 3 Centrifuge

Capper / Decapper

Brooks IntelliXCap

Brooks IntelliXCheck

Plate Sealing

KBiosystems KAPS-500 Adhesive Sealer

Agilent PlateLoc Heat Sealer

Storage

Thermo Scientific Cytomat Incubators and Ambient Hotels

HighRes Biosolutions AmbiStore D & M

HighRes Biosolutions MicroServe Stacker

HighRes Biosolutions NanoServe Stacker

Mecour Thermal Tower

Liconic Storage STX and LPX Series

Bulk Dispenser

Thermo Scientific Multidrop Combi nL

Thermo Scientific Multidrop Combi

BioTek MultiFlo FX

Labcyte Deerac LXP

Fritz Gyger Certus Flex

Formulatrix Tempest V2 or V3

Formulatrix Mantis

NOTE: Please check with your local account manager for recent list of device drivers available. 3rd party device specifications can be found at the vendor website, for Labcyte devices please check http://www.labcyte.com/support/specification-sheets.

Additional Supported Devices


SPC-ADRS-1.0 25

LABCYTE INC.

5 – 10 position vacuum delidder

Supports Labcyte MicroClime Lids, BioRad PCR lids, and most ANSI/SLAS low profile automation microplate lids

2D / 1D barcode reader Compatible Barcode Formats: CODE39, ITF, INTERLEAVED 2-of-5, COOP 2-of-5, Codabar, CODE 128,EAN-128, CODE 93, EAN/UPC (A*E)

Echo insert station Holds up to 2 Labcyte source plate inserts for the Echo E5XX series

25 position random Access plate hotels

• Compatible with Echo Qualified 1536/384-well LDV microplates, and standard 1536-well plates

• Rack pitch: 28.6 mm

• Max labware height allowed (including lids): 15.9 mm

20 position random Access plate hotels

• Compatible with Echo Qualified 1536/384-well LDV microplates, Echo® Qualified 384-well Polypropylene plates, Echo Qualified 6-well reservoir and most standard labware within height restrictions stated below

• Rack Pitch: 35.9 mm

• Maximum labware height allowed (including lids): 23.2 mm

Handover nests Location used to transfer labware between robot modules

Regrip nest Location for robot to adjust grip to change between landscape and portrait or adjust grip offset in Z

Supported Accessories and Specifications

26

Power • Two Single-phase 230V AC, 50Hz, 30A drops (regions with 200 - 230V Native Power)• Two 3-phase, 5-wire, 208V AC, 60Hz, 30A drops (regions with 100 - 120V Native Power)

Air

Vacuum

Laboratory floor requirements

To meet docking repeatability specifications, the floor levelness must fall within the range of the following specifications and standards• ASTM E 1155 Standard• FF35/FL25 to FF50/FL30


System Requirements

F-number

Gap under an unleveled 10-foot straightedge (fraction of an inch)

FF12 1/2

FF20 5/16

FF25 1/4

FF32 3/16

FF50 1/6

Floor surface classification

Specified overall flatness

(FF)

Specified overall

levelness (FL)

Maximum Gap

90% Compliance

(mm)

100% Compliance

(mm)

Conventional 20 15 13 19

Moderately flat 25 20 9.5 16

Flat 35 25 6.35 9.5

Very flat 45 35 n/a n/a

Super flat 60 40 n/a n/a

Floor surface classification in ACI 117-061

Although there are no direct equivalents between F-number and straight edge tolerances, ACI 302,"Construction of Concrete Floor and Slabs," give the following table of approximate values:

"Maximum gap section" of chart show the maximum gap between the floor surface and the bottom of the 10 foot straight edge. Note that 90% of the sample must not exceed column 2 and 100% of the sample must not exceed column 3 of the table below.

Clean and Dry Pressure Flow Rate Tubing

Maximum oil content Min. Max. Min. OD

ppm kPa PSI kPa PSI lpm cfm In. mm

0.01 620 90 690 100 180 6.35 3/8 10

Pressure Flow Rate Tubing

Min. Min. ID

Torr mbar In. Hg Lpm cfm In. mm

200 266 22 70 2.5 3/8 9.5

SPC-ADRS-1.0 27

Laboratory environment requirement

• Systems with Ambient Environment: 21 °C ± 2 °C / 10 - 80 % RH• Systems with Low %RH HVAC Integration to achieve 10 % RH: 22°C ± 2 °C / 10 - 50 % RH.

Building Management System (BMS)

The Access system has an option to connect to a lab BMS. This connection is hardwired directly from lab BMS to the top of the robot module and requires 5, 24 - 22 AWG , 24V dry wires. The following figure highlights the connections needed.

System Certification and Compliance Standards

• 2004/08/EC (Electromagnetic Compatibility Directive) – EN 61326-1:2006

• 2006/95/EC (Low Voltage Directive) – EN 61010-1:2001 and EN 60825-1:2007

• Low Voltage (LVD) Directive 2006/95/EC

- EN60204 - 1 Safety of machinery - Electric equipment of machines - Part 1: General Requirement

• Electromagnetic Compatibility (EMC) Directive 2004/108/EC

- EN61000 - Electromagnetic compatibility (EMC)

• Machinery (MD) Directive 2006/42/EC

- EN ISO 10218-1 Robots and robotic devices - Safety requirements for industrial robots - Part 1: Robots

- EN ISO 10218-2 Robots and robotic devices - Safety requirements for industrial robots - Part 1: Robot system and integration

- EN ISO 12100-2010 Safety of Machinery - General principles for design - Risk assessment and risk reduction

• E-stop compliance to EN ISO 13850:2015

• EMC and Leakage Current complies with EN61326 and EN61010

• CE Certified

• RoHS Compliant

LABCYTE INC.

All product names, logos, and brands are property of their respective owners. All company, product and service names used in this document are for identifi cation purposes only. Use of these names, logos, and brands does not imply endorsement.

LABCYTE INC.170 Rose Orchard WaySan Jose, CA 95134 USA

Toll-free: +1 877 742-6548Fax: +1 408 747-2010

SALESNorth America | +1 408 747-2000 | [email protected] | +353 1 6791464 | [email protected] | +81 03 5530 8964 | [email protected] | +61 39018 5780 | [email protected] | +1 408 747-2000 | [email protected]

© 2018 LABCYTE INC. All rights reserved. Labcyte®, Echo®, MicroClime®, the Labcyte logo, Access™, and Tempo™ are registered trademarks or trademarks of Labcyte Inc., in the U.S. and/or other countries.

FOR RESEARCH USE ONLY. Not for use in diagnostic procedures.SPC-ADRS-1.0

AUG 2018

Documents

Version 1.0 | AUG 2018 Access