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Venous Thromboembolism Prevention
August 2010August 2010
Venous Thromboembloism Prevention2
Expected Practice
Assess all patients upon admission to the ICU for risk factors of venous thromboembolism (VTE) and anticipate orders for VTE prophylaxis based on risk assessment
Venous Thromboembloism Prevention3
Expected Practice
Moderate-risk patients (medically ill and postoperative patients): low dose unfractionated heparin, low-molecular-weight heparin (LMWH), or fondaparinux
High risk patients (major trauma, spinal cord injury, or orthopedic surgery): LMWH, fondaparinux, or oral vitamin K antagonist
Venous Thromboembloism Prevention4
Expected Practice
Patients with high risk for bleeding: mechanical prophylaxis
Graduated compression stockings Intermittent pneumatic compression devices
Mechanical prophylaxis may also be anticipated in conjunction with anti-coagulant based prophylaxis regimens
Venous Thromboembloism Prevention5
Expected Practice
Review daily each patient’s current VTE risk factors including
clinical status necessity for central venous catheter current status of VTE prophylaxis risk for bleeding response to treatment.
Venous Thromboembloism Prevention6
Expected Practice
Maximize patient mobility to reduce the amount of time the patient is immobile
Ensure that mechanical prophylaxis devices are fitted properly and in use at all times
Venous Thromboembloism Prevention7
Problem Scope and Impact
Most hospitalized patients have at least one risk factor for VTE.
VTE is common and contributes to excess length of stay, excess charges, and mortality.
Primary thromboprophylaxis reduces the morbidity and mortality associated with deep vein thrombosis and pulmonary embolism.
Venous Thromboembloism Prevention8
Supporting Evidence The majority of critical care patients have one or more risk
factors leading to VTE formation Immobilization sedation/neuromuscular blockade CVC’s Surgery sepsis mechanical ventilation vasopressor administration heart failure Stroke Malignancy previous VTE renal dialysis
Venous Thromboembloism Prevention9
Supporting Evidence
Signs and symptoms of VTE are frequently silent and can lead to fatal pulmonary embolism, VTE prophylaxis is recommended for at-risk patients.
Venous Thromboembloism Prevention10
Supporting Evidence
Low dose unfractionated heparin and LMWH are efficacious in preventing VTE in moderate-risk critical care patients.
For patients at higher risk major trauma or post orthopedic surgery, LMWH has been shown to provide superior protection over low dose unfractionated heparin.
Direct thrombin inhibitors can be used in place of low molecular weight heparin or unfractionated heparin in patients with heparin induced thrombocytopenia.
Venous Thromboembloism Prevention11
Supporting Evidence
Mechanical methods of prophylaxis have been shown to reduce the risk of VTE
graduated compression stockings intermittent compression devices venous foot pumps
Mechanical prophylaxis is less efficacious when compared to anticoagulation based therapy.
Mechanical prophylaxis methods do not pose bleeding concerns.
Venous Thromboembloism Prevention12
Supporting EvidenceWritten policies for VTE prophylaxis along
with either standing ICU admission orders increase compliance with prophylaxis measures
A daily goals form, which included VTE prophylaxis, resulted in a significant improvement in increased staff understanding the patient’s daily goals for care and decreased ICU length of stay
Venous Thromboembloism Prevention13
Supporting Evidence
The presence of a CVC is a risk factor for upper extremity VTE population
Several studies identified immobility either as a co-morbidity or independent risk factor.
Compliance monitoring with intermittent pneumatic compression devices demonstrated rates of non-compliance ranging from 22% to 81% in at-risk patients
Venous Thromboembloism Prevention14
Supporting Evidence
Improperly fitted compression stockings producing a reversed pressure gradient were associated with a significantly higher incidence of VTE compared with stockings that were properly fitted
Venous Thromboembloism Prevention15
Actions for Nursing Practice
Ensure that your unit has a written policy for VTE prophylaxis that is updated regularly to reflect emerging evidentiary findings
Ensure that preprinted or computerized admission orders are available and current
Ensure that your unit has an organized process for developing and communicating patient goals (including VTE prophylaxis) to members of the multidisciplinary team
Venous Thromboembloism Prevention16
Actions for Nursing Practice
Educate and routinely evaluate all staff in the use of mechanical prophylaxis devices
Review orders of patients discharged from the ICU to ensure a continuation plan for VTE prophylaxis
Venous Thromboembloism Prevention17
Actions for Nursing Practice
Monitor compliance with VTE prophylaxis policies rates of VTE and pulmonary embolism initiate quality improvement initiatives
Venous Thromboembloism Prevention18
For more information or further assistance, please contact a clinical practice specialist with the AACN Practice Resource Network.
Need More Information?
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