420 Delaware Street SE MMC 508 Minneapolis, MN 55455 (612) 625-8988 (800) 866-2170 lhi@umn.edu http://www.med.umn.edu/cardiology/ http://www.med.umn.edu/lhi/

CARDIOVASCULAR division and LILLEHEI HEART INSTITUTE

innovat ion discovery educat ion

INVESTED IN THE FUTURE The University of Minnesota understands the importance of the Cardiovascular Program, and has made an outstanding investment in faculty support, infrastructure, faculty recruitment, and core research facilities for the program. Over the past two years, the Cardiovascular Program has recruited 15 new faculty members in the fields of cardiogenesis, stem cell biology, myocardial regeneration, and molecular genomics. The University of Minnesota has also committed to the construction of a new 60,000 square foot Lillehei Heart Institute research building. This new building – like the University’s Variety Club Heart Hospital, which was the first heart hospital in the United States in 1951 – will further advance our program and enhance clinical and basic science research and development. Construction is slated to begin in 2011. INNOVATION DISCOVERY EDUCATION These three word sum up what we do, and what we are about. The innovation that translates into therapies. The discoveries that happen every day. The education that trains the next generation of cardiovascular physicians and scientists. The University of Minnesota stands alone in its profound and lasting impact on advancing treatment for heart disease. We intend to continue that noble tradition, and invite you to join us on this exciting medical journey to cure heart disease.

CARDIOVASCULAR division and LILLEHEI HEART INSTITUTE

MEET JOHN WATSON (Number 6, and Number 428) In 1955, John Watson of White Bear Lake, Minnesota was one of the first six children to undergo heart surgery at the University of Minnesota using a bypass pump developed by pioneering surgeon Dr. C. Walton Lillehei and Dr. Richard DeWall. Considered the sickest of the six, he became the only long-term survivor. Almost 10 years ago, Watson unexpectedly collapsed at work. A medical examination revealed severe ventricular heart failure, better known as congestive heart failure and marked by the heart’s inability to adequately pump blood. To help his heart work, a left ventricular assist device (LVAD) was implanted. In December 2001, he became the 428th person to receive a heart transplant at the University of Minnesota. Today at age 62 and semi-retired, Watson is one of the staunchest friends of the University of Minnesota's Cardiovascular Program. “There’s no place like the University of Minnesota for everything to do with heart care—it’s the best,” Watson says. “I’m proof of that.”

Nationally recognized for our profound and lasting impact on advancing treatment for heart disease.

HEART DISEASE HEART DISEASE IS THE #1 CAUSE OF DEATH IN THE U.S. AND WORLDWIDE, AND AFFLICTS PEOPLE OF ALL AGES WOMEN ACCOUNT FOR HALF OF THE DEATHS DUE TO HEART DISEASE EVERY YEAR ABOUT 785,000 AMERICANS HAVE A FIRST HEART ATTACK, WHILE ANOTHER 470,000 WHO HAVE ALREADY HAD ONE OR MORE HEART ATTACKS HAVE ANOTHER ATTACK IN 2010, HEART DISEASE WILL COST THE UNITED STATES $316.4 BILLION ACROSS THE UNITED STATES, DEATH RATES DUE TO HEART DISEASE IN 2006 WERE HIGHEST IN MISSISSIPPI AND LOWEST IN MINNESOTA

A dedicated program at work for you A LEGACY OF CARE THA T CONTI NUES TO REVOL UTIONIZE CARDI OVASCULAR MEDI CI NE

Outstanding, innovative, and pioneering clinical care is the foundation for everything we do – and the driving force behind the University of Minnesota’s Cardiovascular Division and Lillehei Heart Institute. A cardiovascular program, that since the 1950s, has consistently ranked among the best in the United States because of our outstanding patient care and revolutionary discoveries and innovations. The Cardiovascular Program offers a full range of patient care in every subspecialty of cardiovascular disease including interventional catheterization, heart failure and transplantation, arrhythmia, vascular disease, heart disease prevention, and non-invasive imaging; which includes ECHO, nuclear, and CT/MRI imaging.

But our program is not only about clinical care. Nationally recognized for basic-science, clinical, and translational research, the Cardiovascular Program’s physicians and scientists are involved with the latest research every day, and translate those discoveries into therapies and strategies that provide hope to even the sickest patients. Today, 60 years and thousands of patients after we began, the University of Minnesota Cardiovascular Division and Lillehei Heart Institute remains at the center of cardiovascular research and treatment. In our quest to become one of the best programs in the world, we have evolved into one of the largest and most vigorous programs in the nation, while at the same time never forgetting that helping those with cardiovascular disease is our passion.

the center of cardiovascular research and treatment

OUR GOAL IS A WORLD FREE OF CARDIOVASCULAR DISEASE

INNOVATIVE CLINICAL CARE Our Cardiovascular Program is like no other in the United States. Through various centers of excellence, enhanced local, regional, and global collaborations, and expert education, our doctors provide clinical care that is both compassionate and state-of-the-art in prevention and diagnosis. LILLEHEI HEART INSTITUTE The Lillehei Heart Institute is built on the legacy of University of Minnesota professors who blazed the trail in heart surgery; pioneered new therapies in heart failure; established the link between cholesterol and arteriosclerosis; and set the stage for world-renowned programs in organ transplantation. Named after Dr. C. Walton Lillehei, world-renowned as the "Father of Open-Heart Surgery," the Lillehei Heart Institute brings together faculty committed to cardiovascular scholarship and lessen the toll of cardiovascular disease in all of us. Ever expanding, the Lillehei Heart Institute currently includes over 100 active faculty and staff, while housing close to 25 major research grants.

RESEARCH TO FIND A CURE The dedication and work of our scientists and physicians to continually discover, and then translate their research discoveries into new clinical treatments has transformed our

over the past two years we have established and recruited new research teams, and have developed state-of-the-art research facilities that have resulted in a 250% increase in research funding and five large programmatic grants. The Cardiovascular Division and Lillehei Heart Institute are currently home to over 150 active researchers with close to 90 currently funded projects, generating over $10 million per year in grant support for their investigations. While our research has grown in national prominence, we never forget the reason we work so hard – to find a cure for heart disease.

Cardiovascular Program into one of the largest and most prestigious in the nation. Starting 60 years ago, with the first world’s first successful open heart surgery, the world’s first successful heart/lung machine, and the world’s first pacemaker, our research has always been instrumental to revolutionizing the study of heart disease. This philosophy has not changed, as

in·no·va·tion [inə’veiʃən] n

1. something newly introduced, such as a new method or

device

2. a creation (a new device or process) resulting from study

and experimentation

3. the driving force behind the Cardiovascular Program at the

University of Minnesota

dis·cov·er·y [di’skʌvəri] n pl -eries

1. the act, process, or an instance of discovering

2. the act of detecting something;

catching sight of something

3. a productive insight that occurs almost daily within the Cardiovascular

Program at the University of Minnesota

ed·u·ca·tion [,ɛdjʊ’keiʃən] n

1. the knowledge or skill obtained or developed by a learning process

2. a program of instruction of a

specified kind or level

3. an instructive or enlightening experience that over 70% of

Minnesota’s cardiologists gained at the University of Minnesota