Topic 1- Introduction to Cell

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    Topic 1

    Introduction to cell

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    Biologyis the systematic study of life

    The branch of science that is concerned with

    the study on life and living organisms

    The characteristics of life: All living organismsshare the following characteristics of life:

    i) Organization: the levels of biological organization

    extend as follows:

    Introduction

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    ii) Acquisition of materials and energy from the

    environment

    iii) Reproduction: they produce offspring

    iv) Respond to stimuli: they react to internal and

    external events

    v) Internal homeostasis

    vi) Growth and developmentvii) Adaptations to a changing environment

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    The Diversity and Unity of Cells

    Cells are the fundamental units of all living

    things

    Although the diversity organisms isincredible, the cells of all organism share

    many similarities.

    Only a few structural differences betweenmost types of cells.

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    Cell Theory

    All organisms are composed of one or

    more cells.

    Cells are the basic living unit of structureand function in organisms.

    All cells come only from other cells.

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    Cell Theory (cont.)

    Four generalizations constitute the cell theory:

    1. Every living organism consists of one ormore cells

    2. A cell is the smallest unit of life, individuallyaliveeven as part of a multicelled organism

    3. All living cells come from division ofpreexisting cells

    4. Cells containhereditary material, which

    they pass to their offspring during division

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    Two main types of cells

    There are 2 components to the cell theory.

    i) All organisms are composed of cells.

    ii)Cells come only from preexisting cells.

    All cells have an outer membrane called theplasma membrane.

    The plasma membrane encloses asemifluid substance called thecytoplasmand the cells genetic material.

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    The word cellentered biology in the 17thcentury.

    Anton van Leeuwenhoekis recognized forinventing one of the earliest microscopes and

    observing a first cell.

    Robert Hookeconfirmed earlier findings andcoined the term cell.

    Matthias Schleidenstated that plants are

    composed of cells.

    Theodore Schwannstated that animals are

    composed of cells.

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    Size of Cell

    Cell size varies, but are quite small.

    A frogs egg is about 1 millimeter (1mm) in

    diameter. Large enough to be seen by naked eye

    Most cells are smaller than 1mm.

    Some cells are as small as 1 micrometer

    (1mm).

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    Size of Cell (cont.)

    Cells being small is an advantage formulticellular organisms:

    Nutrientssuch as glucose can enter thecell.

    Wastessuch as CO2 can exit cell.

    Therefore surface area affects the ability toget materials in and out of a cell.

    As cells increase in volume, the proportionateamount of surface area decreases.

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    Size of Cell (cont.)

    For a cube-shaped cell:

    The volumeincreases by the cube of the

    sides (height X width X depth). The surface area increases the square of

    the sides and the number of sides (height

    X width X 6). If a cell doubles in size, its surface area

    increases fourfold, while the volume

    increases eightfold.

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    Surface Area / Volume Ratio

    All 3 have the same volume, but the group

    on the right has 4 times the surface area

    One 4-cm cube Eight 2-cm cubes Sixty-four 1-cm cubes

    Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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    How scientist study cells?

    Most cells are far too small to see withthe naked eye

    We use different types of microscopes

    and techniques to reveal cells andtheir internal and external details

    Cells under the microscope

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    Cells under the microscope (cont.)

    Our bodies are comprised of severalhundred different types of cells, withbillions of each cell type present.

    Each type of cell is specialized in itsparticular function.

    Cells are so small that a microscope isneeded to see them.

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    Types of microscopes

    1. Light microscopes

    2. Phase-contrast

    microscopes

    3. Fluorescence

    microscope

    4. Electronmicroscopes

    5. TransmissionelectronMicroscopes

    6. Scanning electronmicroscopes

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    Examples of microscopes

    Compound light microscope Transmission electronmicroscope (TEM)

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    phosphor

    screen

    incoming electron beam

    condenser

    lens

    specimen

    on gridobjective

    lensprojectivelens

    Transmission electron microscope (TEM)

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    Cells under the microscope (cont.)

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    Cells under the microscope (cont.)

    Light microscopes can be used to view

    cells but not in much detail.

    Electron microscopes allow the

    structure of cells to be viewed in greater

    detail.

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    Sizes of Living Things

    10 m1 m0.1 m1 cm1 mm100 m10 m100 nm10 nm1 nm0.1 nm

    mousefrog egg

    human eggmost bacteria

    virus

    protein

    atomant

    electron microscope

    light microscope

    human eye

    human

    blue whale

    chloroplastrose

    1 km100 m1 m

    amino

    acids

    plant and

    animal

    cells

    ostrich

    egg

    Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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    ALight micrograph. BLight micrograph. CFluorescence

    micrograph.

    DA transmission

    electron micrograph

    reveals fantastically

    detailed images of

    internal structures.

    E A scanning

    electron micro-graph

    shows surface

    details. SEMs may beartificially colored to

    highlight specific

    details.

    A reflected light

    microscope captures

    light reflected fromspecimens.

    A phase-contrast

    microscope yields high-

    contrast images oftrans- parent

    specimens. Dark areas

    have taken up dye.

    This image shows

    fluorescent lightemitted by

    chlorophyll

    molecules in the

    cells.

    Different views of different microscopes, reveal

    different characteristics of the same organism

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    Cells under the microscope (cont.)

    Cells are small because they are limited bytheir surface-area-to-volume-ratio.

    The surface area of a cell is critical because

    it must be large enough to allow adequatenutrients to enter the cell.

    Cells can increase their surface area with

    specialized projections such as microvilli.

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    Traits common to all cells

    Cells differ in size, shape, and function.

    Although cells differ in size, shape andfunction, each starts out with a plasmamembrane, cytoplasm, and a region of

    DNA (in eukaryotic cells, a nucleus)