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Red blood cell

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Wound in skin

Platelet gather StickyForms a temporary plugin leakingvessel

Produce

Trombokinase

Trombokinase

Ion Calcium

Prothrombin

Need

Vitamin D

Thrombin

Fibrinogen

Fibrin

Forms the threads

of the clot

Later

Harden (scab)

Mechanism of blood clotting

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Whenever an injury occurs a chain reaction is setoff.

Wound in skin

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Wound in skin

Platelets gather at a site of the injury andbecome sticky

Platelet

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Forming a temporary plug in the leakingForming a temporary plug in the leakingvesselvessel

Wound in skin

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Prothrombin (non-active enzyme) need ionProthrombin (non-active enzyme) need ion

calcium to convert into thrombin.calcium to convert into thrombin.

Trombokinase

Ion CalciumProthrombin

Vitamin K

Thrombin

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Thrombin converts soluble fibrinogenThrombin converts soluble fibrinogen

(plasma protein formed by the liver)(plasma protein formed by the liver)into insoluble fibrin. Fibrin forms theinto insoluble fibrin. Fibrin forms the

threads of the clotthreads of the clot

Thread of clot

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A mesh-like network ofA mesh-like network offibrin traps red bloodfibrin traps red blood

cells together, formingcells together, forming

the blood clot, whichthe blood clot, which

later hardens into alater hardens into a

scab.scab.