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Rapidly expanding research on a national basis imposes an

obligation on manufacturers of laboratory apparatus and callsfor greatly increased production of quality instruments. As our

part in this expanding program, we have recently completedconstruction of this modern factory building. Here, Interna-tional Centrifuges of traditional quality are now being producedin greater numbers than ever before. In announcing our new

address recorded below, we reaffirm our faith in the future ofresearch and pledge the scientist our continued support.

* I ** 'I 6

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--- --- 11

New (3rd)

Schneider and Karpovich on the Edition

PHYSIOLOGY ofMUSCULAR ACTIVITYLong awaited by educators, the ANew (3rd) Edition of this basic text

will undoubtedly prove one of the most popular books in the field.

Teachers have always appreciated the great clarity with which Dr.

Schneider describes the physiologic processes underlying physical ac-

tivity, while students have applauded the practical application of the

facts to the everyday problems of training, fatigue, and physical fitness.

For the New (3rd) Edition the material has been thoroughly revised in

order that it may more precisely meet the needs of today's courses.

Chapters are included on: The Role of Oxygen in Physical Exertion;Work, Energy, and Mechanical Efficiency; Respiration; Blood Composi-tion and Transportation of Gases; Blood Circulation and the Heart; The

Pulse Rate; The Arteries and Arterial Blood Pressure; The CapillaryCirculation, Venous Blood Pressure and the Venous Return; Coordina-

tion of Functions; Physical Work in Relation to External Temperature;The Fuel for Muliscular Work; etc.

By EDWARD C. SCHNEIDER, Emneritus Professor of Biology, WesleyanUniversity; and PETER V. KARPOVICH, Department of Physiology,Springfield College. 346 pages, 51l" x 81", illustrated. Nc w (3rd)Edition-Ready in June.

W. B. SAUNDERS COMPANY

West Washington Square Philadelphia S

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C

Vol. 107 No. 2781 Friday, April 16, 1948

CONMTENMTS

Some Recommendations of the Presi-dent's Commission on Higher Educa-tion:Alfred B. Bonds, Jr ........... 379

Adjustments in University Plans andPrograms to Meet Long-RangeNeeds:Arthur S. Adams .384

N ew sandNotes...........................8....6...................................... 386

Comments and Communications 391

Technical PapersThe Laboratory Growing of Quartz:Danforth R. Hale .393

Effect of Diethylstilbestrol on the ThyroidGlands of Chicks Receiving Thiouracil:Jean E. Selle and Raymond M. Selle 394

Crystalline Vitamin B12:Edward L. Rickes, et al ..396

Activity of Vitamin B12 for the Growth ofLactobacillus lactis: Mary Shorb 397

Activity of Vitamin B12 in Addisonian Per-nicious Anemia: Randolph West.398

In the LaboratoryStabilization of Prothrombin Activity by Freez-

ing: Application to the Standardization ofProthrombin Determinations:Alexander Randall, IV, and J. P. Randall 399

An Improved Method of Precipitating andDrying Vinyl Copolyiners: Harold Werbin 400

Automatic Masking of Lantern Slides:D. Eugene Copeland ................. 401

A Simple Graphical Solution for Potency Cal-culations of Multidose Assays:

Robert A.Harte 401

A Method for Obtaining Massive Growth ofBacteria in Fluid Media:J. Howard Brown and Ronald M. Wood ...... 402

Book ReviewsPhysical fitness appraisal and guidance:

Thoinas Kirk Cureton, Jr.Reviewed byDavidB. Dill ................................... 403

Hearing aids: an experimental study of designobjectives: Hallowell Davis, et al.Reviewed by Mark B. Gardner ...403

The engrammes of psychiatry:J. M. Nielson and George N. Thompson.Reviewed by William T. Lhamon ........................ 403

Scientific Book Register. 404

(Cover photo by World Wide Photos.)

Science, a weekly journal, is published each Friday by theAmerican Association for the Advancement of Science atThe Business Press, Incorporated, N. Queen St. and McGovernAve., Lancaster, Pa. Founded in 1880, it has been since1900 the official publication of the AA.AS. Editorial and Ad-vertising Offices, 1515 Massachusetts Avenue, N.W., Wash-ington 5, D. C. Telephone, EXecutive 60 or 6061. Cableaddress, SCIMAG, Washington, D. C. Entered as second-class matter at the Post Office at Lancaster, Pa., January 13,1948, under the Act of March 3, 1879. Acceptance for mail-ing at the special rate postage provided for in the Act ofFebruary 28, 1925, embodied in paragraph 4, Sec. 538, P. L.

and R., authorized January 13, 1948Articles offered for publication should be sent to the Edi-

tor. The AAAS assumes no responsibility for the opinionsexpressed by contributors. Membership correspondence forthe AAAS should be sent to the Administrative Secretary.Annual subscription, $7.50; single copies, $25; foreign

postage (outside the Pan-American Union), $1.00 extra;

Canadian postage, $50 extra. Remittances and orders forsubscriptions and single copies should be sent to the Circula-tion Department, AAAS, North Queen Street and McGovernAvenue, Lancaster, Pennsylvania,- and 1515 MassachusettsAvenue, N.W., Washington 5, D. C. Claims for missing num-bers will not be allowed if received more than 60 days fromdate of issue. No claims allowed from subscribers in CentralEurope, Asia, or the Pacific Islands other than Hawaii or be-cause of failure to notify the Circulation Department of achange of address or because copy is missing from the files.Change of address. Four weeks notice is required for

change of address. This should be sent to Science, 1515Massachusetts Avenue, N.W., Washington 5, D. C. Whenordering a change, please furnish an address stencil labelfrom a recent issue. Address changes can be made only if

the old as well as the new address is supplied.The American Association for the Advancement of Science

also publishes The Soientqic Monthly. Subscription rateson request.

Mildred Atwood Theo. J. Christensen

Acting Efditor Business Manager

Publications CommitteeFarrington Daniels, John E. FlynI, KHrtley F.

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Problem: To break the bottleneckin electrophoretic research, the

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THE SOLUTION: ELECTROPHORENISApparatus

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CONVENIENT & COMPACT . . . The apparatusis only 38 inches wide. 30 inches deep. and 60inches high. All operating controls are on a singlepanel and are manipulated from a fixed position.Has large work surface for preparatory operations.Complete operating technique can be learned in afew hours. Temperature control system is auto-matic. Refrigeration system requires no attention.Ready for operation by plugging the cord into a115-volt 60-cycle circuit.

PRECISE. . . The optical elements are coated andspecially designed for Schlieren observation. Opticaltolerances are superior to those of the finest photo..graphic objectives. The apparatus resolves proteinconcentrations of less than 0.12% in macro cellshaving an optical path length of 2.5 cm., and lessthan 0.2% in micro cells having an optical pathlength of 1.5 cm. Differences in refractive indexof 0.00027 with the macro cells and 0.00045 withthe micro cells can be distinguished. Both ascend-'ng and descending boundaries can be observed.Extraordinary line voltage fluctuations do not affectcurrent passing through the c~ells. Bath temperatureis held constant within plus or minus 0.05'C. orbetter.

COMPLETE . . Provides continuously variable andregulated high voltage supply . . . vibrationless,automatic electrical refrigeration . . . highly sensitiveSchlieren optical system . . . storage and freezingcompartment for serum or other samples . . . photo.graphic enlarger and darkroom unit . . . dialysisfacilities . .. casters for easy positioning.

We invite inquiries on electrophoresisproblems or on specialized needs for highprecision and research accessories.

VERSATILE . . . Affords instantaneous choice ofpattern-bright line (slit); dark line (bar); dark pat-tern (straight-edge). Two samples-can be onalyzedsimultaneously. Micro and macro analytical and/orroutine clinical cells (10 cc. to less than 1 cc.) canbe used. Diffusion, adsorption and refractive indexmeasurements can be made. Either cut film (31/x44¼in.) or No. 116 roll film can be used. Patterns,which can be observed or photographed. may besuperimposed on standard curves or on patterns ofprevious development.

RAPID ... Six complete electrophoresis determinationscan be made in nine hours in any routine clinicallaboratory. and dialysis facilities are more thanadequate for this output.

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Write for Bulletin 2767A

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A L%~L

SPECTROGRAPH ACCESSORIES

491e/ r by Bausch &; Lomb.,for Safer, Faster, More Efficient Spectrography

SAFETY ARC and SPARK STAND ... Makes itpossible for you to use high voltages from 2,000 to5,000 at 2 to 10 amperes for excitation with perfectsafetyl Electric current can be on only when the dooris closed and the charged parts arefully enclosed inthe chamber. Operator is completely protected fromcontact with charged parts.

SPECTRUM PLATE PROJECTOR... For newspeed, convenience, and accuracy in examination,line identification, and measuring wavelengths onspectrum plates. Gives you a clear, sharp, magnifiedimage. Extremely simple to operate.

ELECTRODE SHAPER ... Now you can form theends of graphite rods into electrodes of any desiredform with surprising speed and simplicity! All you

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BRIQUETTING PRESS . . . Accuracy in spectro-graphic analyses of samples in loose form resultsfrom using this new press which forms solid pelletsthat withstand arc and spark excitation without lossof material. Ruggedly built for long service.

These four accessories will make your spectrographic laboratory more valuableand efficient. Write for detailed literature, which has just been prepared, toBausch & Lomb Optical Company, 642-Q St. Paul Street, Rochester 2, N. Y.

BAUSCH & LOMBOPTICAL COMPANY ROCHESTER 2, N. Y.

8

ing their synthesis programs the com- The first meeting of the Committeemercially available compounds will be was held February 11, when prepara-supplemented by others prepared in tions were begun for the first GeneralAEC laboratories. Assembly of the International Union

The Commission has outlined the at Harvard University, July 28-Au-procedure for obtaining compounds gust 30.containing C14 from commercial firmsas follows: The Navy Department is currently

(a) Communicate with the company expanding three comparatively new,to determine the availability and price permanent laboratories in California.of the compound desired. One of these, the Naval Ordnance Test

(b) Send to the Isotopes Division Station, China Lake (formerly Inyo-an "Application for Radioisotope Pro- kern), 160 miles from Los Angeles,curement, " AEC Form 313, requesting originally an activity of CalTech, isC14 in the form of the compound de- presently engaged in research, develop-sired and mentioning the name of the ment, and test work with ordnancefirm from which purchase is to be equipment and explosives. Another ofmade. After review and approval of these is the Navy Electronics Labora-the application, the Isotopes Division tory, San Diego, which is an outgrowthwill return two copies of "Authori- of work done by the University ofzation for Radioisotope Procure- California. Here the work concernsment," AEC Form 374. research, development, and testing of

(c) Place a purchase order for the electronic control devices, detectionallocated C14 compound with the com- and instrumentation equipment, andmercial firm. The original copy of training aids. The third is the NavyForm 374 must be attached to the Air Missile Test Center, situated atpurchase order. Point Mugu, 60 miles north of LosOn April 1 the Commission also Angeles. The Center's work consists

announced that certain radioisotopes of flight and laboratory testing anduseful in therapy, diagnosis, and re- evaluation of guided missiles and theirsearch in cancer will now be distributed components.in this country without charge, except Each of these establishments needsfor handling ($10 per shipment) and qualified personnel in a variety oftransportation. These isotopes, with scientific fields, and it has been an-their catalogue numbers, are: Iodine nounced that examinations are now131 (S-2), Phosphorus 32 (S-3), and open for professional positions asSodium 24 (73). They may be ob- chemist, mathematician, metallurgist,tained by submitting AEC Form 313 meteorologist, physicist, statistician,to the Isotopes Division. scientific research administrator, and

scientific stall assistant. Examina-A British National Comiittee for tions are also open in various branches

Crystallography has recently been of the engineering profession. Sala-formed by the Royal Society with Sir ries for most of the positions rangeLawrence Bragg as chairman. Repre- from $3,397 to $9,975 per annum.senting the Royal Society on the According to the Navy DepartmentCommittee are W. T. Astbury, J. D. Joint Board of U. S. Civil ServiceBernal, Mrs. D. C. Hodgkin, Mrs. K. Examiners, 1030 East Green Street,Lonsdale, Sir George Thomson, and Pasadena 1, California, from whichC. E. Tilley. Representatives of other further information may be obtained,organizations include G. M. Bennett the work programs of these labora-(Chemical Society), D. A. Oliver (In- tories are planned and directed-by anstitute of Metals), E. G. Cox (Insti- outstanding stagf of civilian scientists,tute of Physics), C. Sykes (Iron and and liaison is maintained wth other re-Steel Institute), F. A. Bannister search organizations, universities, and(Mineralogical Society), and H. Wil- scientific associations.man (Physical Society). P. P. Ewald,B. C. Evans, and W. H. Taylor, as U. S. entomologists will undoubt-members of the Provisional Executive edly be interested to hear that FritzCommittee of the International Union Priefert, well-known German entomol-of Crystallography, are ex-officio mem- ogist, has offered to send free ofbers of the National Committee. charge to individual entomologists, in-

stitutions, or societies who have possi-bly aided him during past years in-sects which he collects and prepares.Because he and his wife are now livingin one small room, he does not wish tobegin extensive collections for him-self. His own entomological collec-tions, consisting of some 40,000 speci-mens, were lost. Knowledge of Mr.Priefert 's offer has come to us throughE. 0. Essig, chairman of the Divisionof Entomology and Parasitology, Uni-versity of California AgriculturalExperiment Station. In transmittingthis information Dr. Essig states:"This is an unusually generous offer,and I am sure that many systematicentomologists in this country might beinterested in accepting it . . . possiblyMr. Priefert is in need of things thatwould enable him to get some satis-faction in later years out of doingsome more work in entomology. Sincehe has lost his collection, perhaps hewould like to have some pamphlets andbooks, if not actually the necessitiesof life. " The Prieferts are now livingat 24 Stade, Kehdingermiihren 6, Ger-many.

Make Plans forAmerican Physical Society, 285th

meeting, April 29-May 1, Washington,D. C.

Nebraska Academy of Sciences,58th annual meeting, April 30-May 1,University of Nebraska, Lincoln.

New York State Geological Asso-ciation, annual field conference, April30-May 1, Hamilton College, Clinton,New York.

West Virginia Academy of Sci-ence, April 30-May 1, West VirginiaSchool of Technology, Montgomery,West Virginia.

American Society for Clinical In-vestigation, May 3, Chalfonte-HaddonHall, Atlantic City, New Jersey.

A A

AAAS

Centennial CelebrationWashington, D. C.

September 13-17, 1948

A *SCIENCE, April 16, 1948, Vol. 107390