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7/30/2019 Reliable Science on the Pill
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Reliable science on the pill
There are many conflicting researches being bandied around on the contraceptive pill, the center of the
RH debate. In the midst of this, it should be clear that in any given question (is the pill unsafe or safe,
abortifacient or not), only one side is true and the other false, since it is impossible for exact
contradictories to be both true.
Due to the great emotions this topic engenders and the presence of ideologies, both secular and
religious, it is all the more necessary to adopt a calm and objective attitude. For this, we have to clarify
the relevant criteria to arrive at scientific truth and certainty, and if this is not possible, to arrive at the
most reliable science on the contraceptive pill.
We believe that given the enormity of the questions, research should offer (1) the latest findings,
because a 1999 study can very well be overturned by a 2000 study, (2) the most comprehensive study,
with special emphasis on meta-analysis or a systematic and extensive review of current literature, and
(3) the most authoritative and prestigious peer-reviewed journals and scientific experts, and (4) themost unbiased studies that are above the partisan ideological influence of pro-RH and anti-RH lobbyists.
Thus for a serious national debate on scientific issues, we should not use sources such as blogs, pro-life
magazines, pro-abortion websites, and we should use with discernment research that is directly
produced by political, commercial, religious advocates. The only exception is when the conclusion of
these groups run counter to their advocacies.
We humbly offer what we believe are the latest, most comprehensive, most authoritative and
prestigious, and most unbiased studies that we know. In this on-going debate, we would gladly be told
of new, additional data that outdo the reliability of these studies.
Cancer, stroke and heart attacks
A monograph released just last year (2011) by a working group under the WHOs International Agency
for Research on Cancer (IARC) made an overall evaluation that oral combined estrogenprogestogen
contraceptives are carcinogenic to humans. The 2011 report classified the pill as a Group 1 carcinogen,
which means the highest level of evidence of cancer risk. It specified the types of cancer the pill causes:
Oral combined estrogenprogestogen contraceptives cause cancer of the breast, in-situ and invasive
cancer of the uterine cervix, and cancer of the liver.
This is the third time the Lyon, France-based IARC evaluated the carcinogenicity of pills. The earlier
monographs were published in 1989 and 2007. Summarizing its review, the 2011 IARC monograph said:There are increased risks for cancer of the breast in young women among current and recent users
only. This effect was noted particularly among women under 35 years of age at diagnosis who had
begun using contraceptives when young (< 20 years), whereas the increased risk declined sharply with
older age at diagnosis.. (WHO-IARC findings on Combined Estrogen-Progesterone Pills, retrieved from:
monographs.iarc.fr/ENG/Monographs/vol100A/mono100A-19.pdf)
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On breast cancer, the Mayo Clinic, consistently considered as one of the best hospitals in the world,
published in 2006, an article entitled Oral Contraceptive Use as a Risk Factor for Pre-menopausal
Breast Cancer: A Meta-analysis. The meta-analysis, a study of world scientific literature on this issue,
concluded that use of the pill is linked with statistically significant association with pre-menopausal
breast cancer. The association was 44% over baseline in women who have been pregnant and took the
pill before their first pregnancy. (See sidebar for more data)
In 2010, the Cancer Epidemiology, Biomarkers & Prevention published a study which concluded that the
current use of the pill carries an excess risk of breast cancer". It also stated that "Previous studies
convincingly showed an increase in risk of breast cancer associated with current or recent use of oral
contraceptives from the 1960s to 1980s."
On cervical cancer, a systematic review of literature of 2003 published at the Lancet, one of the leading
medical journals in the world, stated: long duration use of hormonal contraceptives is associated with
an increased risk of cervical cancer.
On heart attacks, a 2005 meta-analysis at The Journal of Clinical Endocrinology & Metabolism stated that
a rigorous meta-analysis of the literature suggests that current use of low-dose OCs significantly
increases the risk of both cardiac and vascular arterial events.
On stroke, one of the lead scientific journals of the American Heart Association, precisely titled Stroke,
published a study in 2002 that concluded that indeed the pill confers the risk of first ischemic stroke.
Replies and counter-replies
To these findings a number of possible replies can be given.
First, all medications have side-effects, even paracetamol. Our reply would be: Paracetamol is notusually taken everyday, but pill is. Also, the risk of the side effect should be proportionate to the reason
for taking a medicine. In the case of contraceptives, there is no disease, since a child is not a disease.
Moreover, the three side-effects which have strong empirical proof are not superficial side-effects but
some of the most common causes of death among Filipinos.
A second possible reply: according to some studies, there is only a slight risk. Reply: We have to take
note of the actual words of the most reliable studies: excess risk of breast cancer and significantly
increases risk of heart attacks. And if, for the sake of argument, the risk were slight, cancerthe big C--
is no light matter.
Thirdly, someone might say: government authorities prescribe them. Our reply: not all governmentorders are correct. They can also make mistakes, especially now when foreign governments and wealthy
and powerful commercial lobbies are actively pushing for the RH Bill .
A fourth reply would be that the pregnancy is a greater risk than cancer. On the contrary, the datum
from the science shows pregnancy has a protective effect against breast cancer. The journal Breast
Care: A Multidisciplinary Journal for Research, Diagnosis and Therapy published a study in 2009 that
showed that A meta-analysis of large Scandinavian epidemiological studies found that [women who
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have never given birth] have a 30% increased risk compared with women who have had at least 1 full-
term pregnancy. Additionally, an increasing protective effect was found with increasing number of full-
term pregnancies. For each birth, the risk was reduced by about 7%.
Abortifacient effects
Some people might still decide to take the pill or to prescribe it in the name of helping the woman
avoid an onerous pregnancy. However, another aspect has to be taken into account. A third party
outside of the doctor and of the woman: the possible presence of a child.
The question of whether the pill is abortifacient [induces abortion or a miscarriage] or not is of
inestimable significance, because the value of a human being cannot be measured.
But the first question is: When does a woman have a child, another human, in her womb? Based on the
most authoritative and unbiased sources, the most reliable answer is: at fertilization, when the human
male sperm unites with the human female egg. This conclusion was the overwhelming agreement in
countless scientific writings, and of most authoritative experts, including scientists from Harvard
Medical School and the Mayo Clinic that were gathered together in the US Senate in 1983. It is aposition upheld in 2011by the Philippine Medical Association in their pro-RH but anti-contraceptive
statement, which they said, is founded strongly on the principle that life or conception begins at
fertilization.(bold letters in the original)
Second question: Does the pill abort the human being at his or her embryonic stage? The answer is yes.
Science has shown that the pill works to stop pregnancy by at least three ways: 1) to prevent the
discharge of female egg cells, a process called ovulation (no egg, no fertilization, no human
being) , 2) to change the cervical mucus which increases the difficulty of sperm entry into the
uterus (no meeting of sperm and egg, no fertilization, no human being), and 3) cause changes
in the lining of the uterus [called endometrium] that makes it hostile for the fertilized egg (thehuman at the embryonic stage) to rest on the mothers womb and obtain nutrition (no food,
death to a previously alive human being).
The third action, which was not widely known until recently, has been shown in many studies. The most
famous of which is the study of Dr. Walter Larimore that was published in one of the scientific journals
of the American Medical Association in the year 2000. Dr. Larimore narrates: I have prescribed the Pill
since 1978. My wife and I used the Pill for years, having no moral concerns about it. Then, in 1995 my
friend showed me a patient information brochure that claimed the Pill had a post-fertilization effect
[effect that could take place after conception] causing ". . . the unrecognized loss of preborn children."
its claims seemed to be outlandish, excessive, and inaccurate. So, I decided to begin a literature search
to disprove these claims to my partner, myself, and any patients who might ask about it. In the end, Dr.Larimore found 94 studies that showed that the pill does indeed have a postfertilization effect. From
then on, he stopped prescribing the pill.
Writing to the Inquirer in July 2011, Dr. Larimore and his co-author, Dr. Joseph Stanford, stressed that
this fact is now so well-established in medical literature that the United States Food and Drug
Administration says of the pill: Although the primary mechanism of action is inhibition of ovulation,
other alterations include changes in the endometrium [ lining for the uterus] which reduce the
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likelihood of implantation [the human embryo adhering to the wall of the uterus]. He also referred to
the pro-RH American Society for Reproductive Medicine that admitted in 2008 that the pill modifies the
endometrium, thus preventing implantation .
How do we explain the third action? While it is true that contraceptive pills are supposed to prevent
ovulation in the first place, hence the fertilization is rendered unlikely, it can never be overemphasized
that no drug is 100% effective.It is a scientific fact that even if a woman is on the pill, ovulation is not
always suppressed, and this is referred to as breakthrough ovulation. This can occur in around 20% of
cycles of women on the pill, and in case this happens, the woman can still get pregnant if she is sexually
active on the day of breakthrough ovulation. This datum is mentioned in a 2003 study published in
Fertility and Sterility, the official science journal of the American Society of Reproductive Medicine.
Thus, as Dr. Walter Larimore and Dr. Stanford said: given that there are highly effective, inexpensive,
totally natural, and non-abortifacient methods of birth control (the methods of modern natural family
planning), it appears that most arguments for using birth -control pills can be said to be advocating
convenience for mothers and fathers at the potential expense of innocent and invaluable human life.
===============
*Kahlenborn C, Modugno FM, Potter DM, Severs WB. Oral contraceptive use as a
risk factor for premenopausal breast cancer: a meta-analysis.Mayo Clin Proc2006;
81(10):1290-1302.
Attribution: From The Polycarp Research Institute Statement on Mayo Clinic Article
(http://www.polycarp.org/statement_mayo_clinic_article.htm); used with permission.
http://www.polycarp.org/statement_mayo_clinic_article.htmhttp://www.polycarp.org/statement_mayo_clinic_article.htmhttp://www.polycarp.org/statement_mayo_clinic_article.htmhttp://www.polycarp.org/statement_mayo_clinic_article.htm