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    WEIGHT KILOGRAMS POUNDS

     AT BIRTH 3.25 7

    3-12 MOS   + 92

      Age (mos) +

    11

    1-6 YRS Age (yrs) X 2 + 8 Age ( yrs) X 5+ 17

    7-12 YRS    7 − 52

      Age ( yrs ) X 7

    + 5

    HEIGHT centimeter Inches

     AT BIRTH 50 20

     AT I YR 75 30

    2 -12 YR Age ( yr) X 6 +77 Age (yr) X 2.5+ 30

    BODY SURFACE AREA :

       ()3600

     

    APGAR

    Sign 2 1 0

    Muscle tone(Acticity)

    active Someflex./ext

    limp

    Pulse >100

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      Aztreonam(Azactam)

    NB2kg: 90mg/k/d q8h IV/IM

    (1st week)120mg/k/d q

    6h (1-4wk)IN,CH: 90-120 mg/k/dq 6-8hSevere or lifethreatening infxn:2 gms IV q 6-8 h

    500 mg,1 g vial

    Cloxacillin(Orbenin,Prostaphlin

     A)

    IN,CH: 50-100 mg/kg/dq6-8 po

     A: 2-4g/d q 6 po

    250, 500mg cap125mg/5ml susp250mg/5 ml susp250 and 500 mgvial

    Oxacillin NB1200g: 50-75 mkd q8-12

    (up to 1week)

    100-150mkd q6-8

    (1-4wks)

    IM/IV over15-30

    minIN,CH: 100-200 mkd q6 IM/IV

    (over 30 mins)50-100mg/kg/day q6 IV

     A: 2-12 g/d q4-6 IM/IV(over 30mins)

    250mg vial500 mg vial

    Nafcillin(Vigopen)

    NB: 40mg/k/d q12 IV(up to 1 wk)

    60-80mg/k/d q 6-8h (1-4wks)IN,CH: 100-200 mg/k/dq 4-6h IV

    250mg/5ml susp250 mg cap500 mg and1 g vial

    Pen V(phenoxymethyl-penicillin)

    50,000-100,000U/kg/day q6high dose: 150,000-200,000 U/kg/day q6PO(Megapan,Pantacillin,Sumapen, medoxypen)

    125mg/5ml(200,000u/5ml)250mg/5ml(400,000u/5ml)500mg cap(800,000 u)

     AqueousPen G

    Benzylpenicillin

    50,000-100,000U/kg/day q6meningitic dose:200,000-400,000U/kg/day q6 IV

    1,000,000 U/vial5,000,000 U/vial

    PENICILLIN G (PENADUR) = Wt x 100 /600

    Benzathine

    Crystalline

    Procaine

    50,000 u/kg singledose IM600,000-1.2 M u IM q3-4 wks(Rheumatic Fever

    prophylaxis)

    NB: 50,000-100,000u/kg q 6

    IV/IMIN,CH: 100,000-250,000 u/kg q

    4-6 IM/IV

    25,000-50,000ukd, IMq 12-24Meningitic: 200,000-400,000Skin infxn:150,000u/k/d x 10 days

    1.2 M & 2.4 M uvial

    1M and 5M u vial

    CEPHALOSPHORINS

    1st GENERATION

    Cephalexinmonohydrate

    TD: 30-50 mg/k/d q6-8OM: 75-100 mg/k/d

    (keflex)100mg/ml drops125mg/5mlsusp,250mg/5ml susp250, 500 mg 1 gcap250, 500 mgpulvule

    Cefalothin Na 80-160 mg/k/d q 6h

    life threatening: up to2g/k/d q4

    1g/vial

    (Keflin)

    Cefazolin NB: 40mg/k/d q 12 (1stwk)

    40-60mg/k/d q8-12 (1-4 wks) IM/IV over 15-30minIN,CH: 50-100mg/k/d q8IM/IV

    (Stancef)500mg &1 g vials

    2nd GENERATION

    Cefaclor(ceclor)

    IN,CH: 20-40mg/kg/daypo q8

     A: 750mg-1.5g q8

    250, 500 mg cap125mg/5 mlsusp250mg/5 mlsusp

    Cefuroxime 100-150 mg/kg/d q8 IM/IV10-15 mkday q12 oral

    250mg/kg/d q 6 IV (forbacterial meningitis)OM: 40mg/k/d q 12>5 yrs: 30 mkd q 12>5 yrs: 40 mkd q 12

     A: 250mg q 12

    Zinacef:250mg, 750mg,

    1.5g vial;125mg/ml susp125mg, 250mg,500mg tabZinnat: 125,250mg sachetsusp., 125mg,250mg, 500mgcoated tab

    Cefetamet CH12 yrs: 500 mg po q 12

    (globocef)250, 500 mg tab250mg/5ml susp

    Cefoperazone CH: 100-150mg/k/d q 6-8IM/IV

     A: 2-12g/d IM/IV q 6-8

    (cefobis)500 mg, 1 gvials

    Cefotaxime IN,CH: 50-100mg/k/d q

    12-16h A (gonorrhea): 500mgIM/IV SD

    (Claforan)

    250mg, 500mg,1 g vial

    Cefoxitin 80-160 mg/kg/day IM/IV q4-8

    (Mefoxin) 1 gvial

    3rd GENERATION

    Ceftriaxone(3rd gen)

    50-100mg/kg/day q12-24IVTyphoid:75-80mg/kg/dayx

     A: 1-4 g/d

    (Rocephin)IM: 250mg,500mg, 1 g (inj.w/ lidocaine)IV: 250mg,500mg, 1 g (inj.w/ 1% water)

    Ceftazidime(3rd gen)

    NB

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    MACROLIDES

     Azithromycin CH: 10mg/kg/day x 3days or alternatively for5 days w/ a single10mg/kg dose on day 1then 5 mg/kg on D2-5

    250mg cap200mg/5mlpowder for oralsuspension

    Clarithromycin

    CH: 15mg/kg q12 po A: 500-1000 mg q12Severe infxn: 2 tab BIDx 6-14 days

    (Klaricid)250mg tab125mg/5mlsusp

    Erythromycin IN,CH: 30-50mg/kg/dayq6 po

    15-30mg/k/d q6

    SIV infusion A: 1-2 g/k/d q6 po1-4gkd q6 IV

    Int. antisepsis: 1 g/dosex 3 doses (1pm,2pm,11pm) the day before sx

    (Erycin,Macrodin,Ilosone

    125mg/5ml;250mg/5ml)100mg/2.5mldrops250mg, 500mgcap200mg/5mlsusp400mg/5mlsusp500 mg vial

    Roxithromycin (Rulid,Macrol)

     A: 1 tab BID po 15-30min before meals

    QUINOLONES

    Ciprofloxacin(Ciprobay)

     A: 500mg-1.5 g po q12100-200 mg as IV

    infusion for 30 min q12Norfolxacin UTI: 200-400 mg BID

    GI infxn: 400 mg BIDGonorrhea: 800mg SD

    OfloxacinUncom.

    UTICompl.

    UTI, Pn, OM,sinusitis, skin& soft tissueinfxn

    GonococcusNon-

    gonococcus

    GI infection

    100mg BID po x 2-7days200mg BID po x 7-14days

    300-600mg as singledose100-200mg BID x 7-14days

    200-300mg BID x 5-7days

    Inoflox, Qinolon

    100, 200mg tab

    Chloramphenicol

    NB1200g: 25-50mkd q12-24h, IV over 15-30 min(1st week)IN,CH: 50-100 mkd q6po

    IM/IV

    (pediachlor,chlormycetin,Chloramol,chlorambid)125mg/5mlsusp250mg, 500mgcap1 g vial

    Clindamycin NB2g: 15mg/k/d q8 or

    20mg/k/d q6IN,CH: 10-40 mg/k/d q6

    (dalacin-C)150mg, 300mgcap

    150mg/ml amp

    Imipenem-Cilastatin

    IN,CH>3mos: 15mg/k/dq6

     A: 1-2 g IV infusion*Crea clearnce of15ml/min should notreceive unlesshemodialysis isinstituted within 48 hrs

    (Tienam)500 mgimipenem500 mgcilastatin, 1amp

    Co-trimoxazole(SMX-TMP)

    5-8 mg/k/d q 12 (Bactrim,Septrin,Microbid)40mg+200mg/5

    mlTriglobe:

    45mg+205mg/5mlBacidal80mg+400mg/5ml160mg+800mgforte tab80+400mgtab/cap160mg+800mgtab

    AMINOGLYCOSIDES 

     Amikacin(Amikin,Pediakin)

    NB: 15 mkd q12 (1stwk)15-22.5 mkd q8-12

    (1-4 wks) IM/IV (over 1-2h)IN,CH,A: 15 mkd div q8IM/IV (over 30-60 min)LD: 10 mg/k/dose

    250mg/ml,(2ml) vial125mg/ml,(2ml) vial50 mg/ml (2ml)vial

    Gentamicin(Garamycin,Servigenta,Progara)

    NB:

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    COLDS PREPARATION:

    Phenylpropanolamine(decongestant)

    1-3mos: ¼ ml q 84-6mos: ½ ml q 87-12 mos: ¾ ml q 81-2 yr: 1 ml q 82-6 yr: ½ tsp q 87-12 yr: 1 tsp q 8

    Disudrin12.5mg/5mlsyr6.25 mg/mldrops

    Combined Prep: Rondec, Drixine, Sudafed, Dimetapp,Decolsin, Triaminic, Tridecon

    Brompheneraminemaleate,phenylephrine,phenylpropanolamine

    1-3 mos: 0.25 cc4-6 mos: 0.5 cc7mos-2 yrs: 1 cc3-12 yrs: 1 tsp TID

    DimetappPer 5 ml syrupPer infant drop

    Iron SupplementDose: 3-5 mg/kg/day (maintenance)

    6 mg/kg/day ( therapeutic dose)preparation: drops 15 mg/ml

    syrup 30 mg/5 ml

    Immuzincdose: 1-2 mg/kg/dayprep: 20 mg /5 ml syrup10 mg/ml drops 

    Nifuroxazide (ercefuryl)< 6 monts 1 tsp BID> 6 months 1 tsp TID

    Calcium Gluconate Dose: 200-300 Ex. WT x dose x prep1.4 kg x 200 mg/ml = 290 mg/ml x 100mg /ml= 2.9 ml

    NaloxoneDose: 0.1 mg/kg/dose IV/IM/SC

    Theophyllineprep: 80 mg/ml

    26.7 mg/mldose: 2.5 mg/kg/dose q12

    ANALGESICS DOSE PREPARATION Aspirin

    ThrombolyticRHD activityKawasaki

    65-130 mg/kg/d q 4-6h3-5 mg/k/day75-100mg/k/day80-100 mkd q 6h x2wksthen 3-5 mg/kg x 6-8

    wks

    80 mg, 325 mgtab

    Diclofenac CH: 50 mg tab BIDduring or after meals

     A: 75-100 mg daily

    25, 50 mg tab100 mg tab (SR)25mg/ml (3ml)amp

    Mefenamic Acid

    6.5 mg/kg/dose q 6 h 50 mg/5ml susp(ponstan,tynostan)250, 500 mgtab/cap

    Paracetamol 10-15 mg/kg/dose q4-6 h

    150mg/ml (2mlamp)125, 250 mgsusp325, 500 mg tab120, 250/5mlsyrup60mg/0.6 mldrops

    BRONCHODILATORS

     Aminophylline 3-5 mg/kg/dose or0.6-0.9 mg/k/hrLD: 5-7 mg/k/doseMD: 3-5 mg/k/dose q 6hr + 2 or 3 cc IVF torun for20-30 min

    25mg/ml (10ml)amp80mg/15ml syr(nuelin)125, 250 mg tab(nuelin,phenedrine)120mg tab(tedral)

    Ipratropium +Fenoterol(Berodual)

    7 yrs, A: 2-10gtts (0.1-0.5 ml)3-6x daily ( min

    interval: 2 hours)

    MDI: 20mcg I +50 mcg F/10ml250mcg I + 500

    mcg F/ 20mlinhalant

    Salbutamol

    Nebulizer

    0.1-0.15 mkd po q 6-8or 2.5 ml tsp q 6-8 ( 6mos-3 y/o) or 5 ml q 6-8 hrsrecommended dose:0.1-0.3 mg/k/d

    0.01 ml/kg (max 1 ml)in 3ml NSS or 5-10gttin 2ml NSS q6

    2mg/5ml syrup(activent,librentin, ventolin)1mg/5ml expector2mg tab2.5mg/2.5ml nebor 5mg/2.5 neb200ug rotacap0.1mg/inhalation(Asmalin)5mg/ml resp soln0.5mg/ml(2ml)amp

    Terbutaline

    Nebulizer

    0.1-0.18-5 mkd po q 8or 0.075 mg/k dose q 6

    hr; or 1 mcg SC to rptprn after 20 min oncedaily

    0.01 ml/kg (max of 1 mlin 3 ml NSS or 5-10 gttin 2 ml NSS) q 6

    0.5mg/ml (1ml)amp

    1.5mg/5ml syr(betalin, bricanyl,pulmoxel,terbulin)2.5 mg tab5 mg tab (ER)2.5mg/ml (2ml)neb0.5mg/dturbohaler, 100 d

    Ketotifen 6mos-3 yrs: 1 drop BIDor 0.25 ml syr BID>3 yrs: 5 ml syrup BID

    (zaldec, Zadilen)1mg cap1mg/5ml syr

    Clenbuterol

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    Solmux) TID4-7 yrs: 5 ml TID8-12 yrs: 7.5 ml

    Solmux:250mg/5 ml500 mg/5mlsuspension

    S-CARBOXYMETHYLCISTEINE (LOVISCOL,MUKINYL,VISCODEC)

    Loviscol 12 yrs: 7.5 ml BID or½ tab to 1 tab BID poor0.025 mg/k IM

    0.5mg/ml syr1mg tab2mg/2ml amp

    Diphenhydramine(Benadryl)

    3-5 mg/kg/day q 6 po,IM, IV

    25mg, 50mg cap12.5mg/5ml syr50mg/ml (1ml)amp

    HydroxyzineHCl (Iterax)

    10 mg OD or1 mg/k/day BID

    0.2 mg/syrup10, 25 mg tabs

    Mequitazine(primalan)

    ½- 2 tabs/day accdgto age

    5 mg tab2.5mg/5ml syr

    Terfenadine(Teldane)

    15-30 mg BID 30mg/5ml syr60mg tab

     ANTI-CONVULSANTS

    Carbamazepine LD: 10-20 mg/kgMD: 5 mg/kg/day

    Tegretol100mg/5ml syr200mg tab

    Clonazepam IN,C 10 yrs: 1- 2 mg/k/dMD:

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    ANTI-ULCER

     Antacid 2-4 tabs chewtab QID1 hr after meals or2-4 tsp QID susp

    Chewable tabs250 and 500 mlsusp

    Cimetidine (tagamet)

    5-7.5mg/kg/dose q 6po/IV or10-20 mg/kg QID

    200,400,800 mgtab100mg/ml (2ml)amp100mg/5ml syrup

    Ranitidine(Zantac)

    2-4 mg/k/dose BID poor1 mg/k/dose TID, IV

    75,150, 300 mgtabs150mg/5ml syrup50mg/2ml amp

    ANTI-SPASMODIC

    Bentyl 2.5-10 ml TID 10 mg tab10mg/5ml syrup

    DicycloverineHCl,Simethicon

    IN: 0.5-1 ml gtt or ½tsp syr QID/TID1-5 yrs: 2.5-5mlTID/QID6-12 yrs: 5 ml

    Relestal: 5 mg/mldrops10mg/5ml syrup

    Hyoscine-N-butyl bromide(buscopan)

    IN: ¼ amp TID IM, SCor slow IVCH, A: 1-2 tabs 3-5 xdaily

    10 mg tab5 mg/5 ml syrup20 mg/ml amp

    ANTI-FLATULENT

    Dimethyl-polysiloxane

     A: 1-2 tab TID po 40 mg tabDisflatyl, Gascon

    ANTI-HELMINTICS

     AlbendazoleNematodeCapillariasis

    Strongyloidiasis

    400 mg po200 mg BID x 10days400 mg q day x 3days

    Zentel200 mg/5ml syr400 mg tab

    Mebendazole(Antiox)

    200 mg po BID x 3days or 500 mg poone dose

    100, 500 mgtab100 mg/5 mlsusp

    Piperazine(Expelin,

     Aloxin)

    75 mg/kg (max:3.5g/d) q day x 2 days(for ascariasis only)

    1.25 mg/5 mlsyr62.5 mg/5 mlsyr

    Pyrantel

    Pamoate

    11 mg/kg/day (max 1

    g) x 3 days

    Combantrin

    250, 500 mgtab125, 250mg/5mlQuatrel:100 mg/5 ml100 mg tab

    ANTI-DIARRHEALS

    Nifuroxazide( Ercefuryl)

    6 mos: 3 tsp daily

     A: 1 cap QID

    200 mg cap220mg/5mlsyr

    Paromomycin +kaolin + pectinBacterialdiarrhea

     AmeobiasisDysenteryPre-opHepatic comaTaeniasisGiardiasis

    6 doses35 mg/kg x 4 consecdays75mg/kg20-50 mg/kg/day x 5days20-30 mg/kg/day x 5-8days

    Humagel150 mg cap50mg/5mlsusp

    OPTICAL ANTI-INFECTIVES:

    Chloramphenicolsolutionointment

    1 gtt 2-4x/day (1 gtt/hr foracute cases) Apply insidesurface of lower lid

    0.25%,0.5%, 1% 5ml drops0.1%,0.5%3.5 g tube

    Framycetinsolutionointment

    1-2 gtts q 1-2h or 1-2 gtts3-4x/day (acute)2-3 application daily or atbedtime

    0.5% 2.5mldrops, 0.5%2.5 g tube

    Sulfacetamide 1-2gtts into lowerconjunctival sac 2-3h

    10% 15%5ml drops

    TobramycinSolutionointment

    1-2 gtts q4½ in ribbon intoconjunctival sac 2-3x/day

    3mg/ml(0.3%),5ml3mg/g

    (0.3%) 3.5gtube

    AMEOBICIDES

    Diloxanidefuroate(furamide,elizol)

    20mg/k/day po TIDx 10 days

    125mg/5ml

    Etofamide(kitnos)

    CH: 15-20ml/kg/dayor 2 tsp TID x 3days

     A: 5 tabs BID x 3days or 1 forte tabBID

    100mg/5ml susp200mg tab500 mg forte

    EAR PREPARATIONS:

    1. Antiseptics with corticosteroidsPolymyxinB+Neomycin+HAA

    Cortisporin 3-4 gtts tid-qid

    5mldrops

    Fluocinoloneacetonide +polymyxin B +neomycin

     Aplosyn,Synalar

    3-4 gtts tid-qid

    5 mldrops

    Triamcinoloneacetonide +neomycin +gramicidine +nystatin

    kenacomb 2-3 gtts tid-qid

    7.5mldrops

    2. Anti-Infectives and Antiseptics

    Chloramphenicol Chloromycetin 2-3 gtts bid-qid

    (5%)5ml

    Polymycin B + glaci

    acetic acid

     Aerosporin 3-4 gtts tid 10ml

    dropsPolymycin B +lidocaine

    Lignosporin 3-4 gtts tid 10mldrops

    3. Miscellaneous

     Antipyrine +Benzocaine +glycerinedehydrated

     Auralgan Moisten cottonplug with solutionthen insert intomeatus tid-qid

    10ml,15mldrops

    Dousatesodium

    otosol Fill ear canal witsoln & stay inposition for 4-5min then insert acotton wool plug x2 consecutivenights

    (0.5%)10 mldrops

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    mo alone pincer grasp,can make a

    crayon mark,releases

    voluntarily

    words otherthan

    mama/dada orproper nouns,

     jargoning(runs severalunintelligible

    wordstogether with

    tone orinflection),one-step

    command withgesture

    actions,comes when

    called,cooperates

    with dressing

    15mo Creeps upstairs,walks back-

    wardsindependen

    tly

    Scribbles inimitation,builds towerof two blocksin imitation

    Uses 4 –6words, followsone-stepcommand

    withoutgesture

    15 –18 mo:Uses spoonand cup

    18mo

    Runs,throwsobjects

    fromstandingwithoutfalling

    Scribblesspontaneous

    ly, buildstower of 3

    blocks, turns2 –3 pages at

    a time

    Mature jargoning(includesintelligible

    words), 7 –10word

    vocabulary,knows 5 body

    parts

    Copiesparent in

    tasks(sweeping,dusting),plays in

    company ofother

    children

    24mo

    Walks upand down

    stepswithout

    help

    Imitatesstroke with

    pencil, buildstower of 7

    blocks, turnspages one at

    a time,removesshoes,

    pants, etc.

    Usespronouns (I,

    you, me)inappropriately, follows two-

    stepcommands,has a 50 – 

    wordvocabulary,

    uses two-wordsentences

    Parallel play

    3 yr Canalternatefeet whengoing up

    steps,pedalstricycle

    Copies acircle,

    undressescompletely,

    dressespartially,

    dries handsif reminded,unbuttons

    Usesminimum of

    250 words, 3 –word

    sentences,uses plurals,

    knows allpronouns,

    repeats twodigits

    Group play,shares toys,takes turns,plays well

    with others,knows full

    name, age,gender

    4 yr Hops,skips,

    alternatesfeet going

    down steps

    Copies asquare,buttonsclothing,

    dresses selfcompletely,catches ball

    Knows colors,says song orpoem from

    memory, asksquestions

    Tells ―talltales,‖ playscooperativelywith a groupof children

    5 yr Skipsalternatingfeet, jumps

    over lowobstacles

    Copiestriangle, ties

    shoes,spreads with

    knife

    Prints firstname, askswhat a word

    means

    Playscompetitive

    games,abides by

    rules, likes tohelp in

    householdtasks

     Age Cal per kgProt g/kg

    0.5 mos 115 3.5

    6-11 mos 110 3.0

    1-2 yrs 110 2.5

    3-6 yrs 90-100 2.0

    7-9 yrs 80-90 1.5

    10-12 yrs 70-80 1.5

    13-15 yrs 55-65 1.5

    16-19 yrs 45-50 1.2

     Age Normal respiratory rate

    20kg

    Ludansmethod

    2 kg

    mild 50 30

    moderate 100 60¼ PLR ¾ D50.9 6-7 hrs

    severe 150 901/3 PLR x 1 hr

    2/3 D5 0.3 or 0.9 6-7hrs

    For every degree rise in temperature add 12% Of maintenance

    IVF components (meq/L)

    Na K Cl base Mg

    D5LRS 130 4 109 28 -

    D5 0.3 Nacl 51 - 51 - -D5 0.45 Nacl 75 - 75 - -

    D5 0.9 NaCl 154 - 154 - -

    D5 mannitol 49 25 19 20 -

    D5 NR 140 5 98 50 -

    D5 NM 40 13 40 16 -

    D5 IMB 25 20 22 23 -

    NP 30 20 25 23 -

    D5NSS 150 - 150 - -

    D5W - - - - -

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     WHO treatment plan (CDD)

    Plan A

     Age in yrs. Give every after BM

    10 As much as tolerated

    Plan B

     Age Weight Ml in 4 hours

    6.5 meg/lMgt: glucose 0.5 – 1 g/kg + insulin 0.1-0.2 units/ kgover 30 minutes

    Bicarbonate Correction

    Total Bicarbonate correction= Wt. x 0.3 x base excess

    Calcium GluconatePreparation 10% calcium gluconate= 10 g = 100 mg100 cc ml

    maintenance = 150-200 mkdayEx. Wt x desired ( 4.1 x 200 = 820mkday)= 100 = 8.2 ml div into doses

    X ml

    Blood Transfusion

    FWB: 10 cc/kg 4-6 hoursPRBC: 10 cc/kg 4 hoursPlt Conc: 1 unit/7 kg fast dripFFP: 10 – 15 cc/kg 2-4 hrsCryoppt: 1unit/5 kg

    How to compute ANC= WBC(% neutrophils + % bands) x 1000

    Fluid Balance

    TFB=Total fluid intake – total fluid outputTFI – ( TFO + (BSAxIWL))TFI = parenteral (IVF/meds) + oralTFO= IWL (400-700/m2) + urine output+ vomitus/ NGT outputTFR = BSA x IWL + ½ U.O in 24 hours(if with diuretics )If w/o diuretic use BSA x IWL + U.O in 24 hours

    Albumin Transfusion

    Dose: 0.5 -1 gm/kgPreparation: 20% 10 gm

    25 % 12.5 gm

    Transfuse 1 vial to run for 2 hrs at 6-7 gtts/min After 1 vial give furosemide (1 mkdose)Give 2

    nd vial then furosemide

    Mobitor VS q 15 mins while ongoing Infusion

    IVIg Computation 

    # of vials needed = WT. x Dose (2g/kg)preparation(g/ml) 

    Ex. 12 kg

    # of vials needed = 12 kg x 2g/kg2.5 g

    = 9.6 vials or 10 vialsInfusion Rate:0.01-0.02 ml/kg/min for the first 30 mins. Via infusion pump ifno adverse reactions noted, may increase to maximum of

    0.04 ml/kg/minEx: 12 kg wt

    Infusion rate of 0.0112 kg X 0.01 x 3o mins = 4 ml* give for ml to run for 30 mins watchout for nausea, vomiting,chills fever, dyspnea, malaise, hjeadache etc.

    2. increase to infusion rate 0f 0.02 x 60 mins12 x 0.02 x 60 = 15 ml to run for 60 min

    3. remaining to run for 14 hours

    IVIg Preparation Available 

    10 ml (500mg/vial)20 ml (1000 mg/vial)

    50 ml (2500 mg/vial)100 ml (5000 mg/vial)200 ml ( 10000 mg/vial)

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     Haesteril 6%

    1 inc. erythropoeisis, inc BM activity, hemolysis

    < 1 dec. erythropoeisis, BM failure

    Hypoglycemia

    normal glucose value(mg/dl) 

    premature 20-60

    neonate 30-60

    newborn:

    1 day 40-60

    >1 day 50-90

    child 60-100

    fasting 70-105

    2 hours PP

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    Ex. BW = 3 kg3 x 2 ml = 6 ml6 x factor = 6 x 0.11

    = 0.66 ccorder: 5.3 cc of present IVF (or D5W) + 0.7 cc of D50-50 tomake D10 as bolus 

    Croup Scoring

    Hypoxic Ischemic Encephalorathy (Sarnat Scoring)

    I II III

    level of conciusness alert lethargy coma

    muscle tone normal orhypertonic

    hypotonic failed

    myoclonus + + -

    seizure - + +

    suck reflex active weak absent

    moro reflex exagerated inc. -

    grasp N or inc exag. -

    dolls eye N overactivity dec. 0r -

    respi. reg. varies apneicCR N or tachy brady brady

    pupils dilatedreactive

    anisoreactive

    anisononreact.

    TABLE 25-3 -- EVALUATION OF CEREBROSPINAL FLUID 

    WBC Count Mean % PMNs

    Preterm 0 –25WBCs/mm

    57%

    Term 0 –22WBCs/mm

    61%

    Child 0 –7WBCs/mm

    5%

    GLUCOSE 

    Preterm 24 –63 mg/dL 1.3 –3.5 mmol/LTerm 34 –119 mg/dL 1.9 –6.6 mmol/L

    Child 40 –80 mg/dL 2.2 –4.4 mmol/L

    CSF GLUCOSE/BLOOD GLUCOSE 

    Preterm 55% –105%

    Term 44% –128%

    Child 50%

    LACTIC ACID DEHYDROGENASE 

    Normal range 5 –30 U/L (or about10% of serum value)

    PROTEIN 

    Preterm 65 –150mg/dL 0.65 –1.5 g/L

    Term 20 –170mg/dL

    0.20 –1.7 g/L

    Child 5 –40mg/dL

    0.05 –0.40 g/L

    CSF, cerebrospinal fluid; PMNs, polymorphonuclearlymphocytes; WBC, white blood cell.

    Modified from Oski FA: Principles and Practice of Pediatrics,3rd ed. Philadelphia, JB Lippincott, 1999. 

    TABLE 25-2 -- EVALUATION OF TRANSUDATE vs. EXUDAT(PLEURAL, PERICARDIAL, OR PERITONEAL FLUID) 

    Measurement*  Transudate Exudate

    Specific gravity 1.016

    Protein (g/dL) 3.0

    Fluid : serum ratio 0.5LDH (IU) 200

    Fluid : serum ratio(isoenzymes not useful)

    0.6

    WBCs‡  1000/mm

    RBCs 1 suggpancreatitis.

    TABLE 1-2 -- MANAGEMENT OF CIRCULATION 

    Location*  Rate

    (per min)Compress

    Ventilat

    Infants 1 fingerbreadth

    below intermammaryline

    >100 5:1

    Children(8 yr)

    Lower half ofstemum

    100 15:2

    TABLE 17-3 -- PREDICTED ENDOTRACHEAL TUBE SIZE ANEXPECTED BIRTH WEIGHT BY GESTATIONAL AGE

    GestationalAge (wk)

    Weight(g)

    ETT Size(mm)

    ETT Depth of Inser(cm from upper li

    24 700 2.5 7

    26 900 2.5 7

    28 1100 2.5 –3.0 7

    30 1350 3.0 732 1650 3.0 7

    34 2100 3.5 8

    36 2600 3.5 8

    38 3000 3.5 –4.0 9

    LABORATORY DIFFERENTIATION OF OLIGURIA Test Prerenal Renal

    FENa 3%

    BUN/Cr ratio >20 :1 1.015

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     TABLE 17-11 -- GUIDELINES FOR USE OF PHOTOTHERAPY IN

    PRETERM INFANTS 2500 >15 >20

    GUIDELINES FOR USE OF PHOTOTHERAPY IN PRETERMINFANTS 2500 >15 >20

    CALCULATION OF EXPECTED COMPENSATORYRESPONSE 

    Disturbance PrimaryChange

    pH ExpectedCompensatory

    Response

     Acuterespiratoryacidosis

    ↑ PaCO2  ↓ pH  ↑ HCO3- by 1 mEq/L

    for each 10 mmHgrise in PaCO2 

     Acute

    respiratoryalkalosis

    ↓ PaCO2  ↑ pH  ↓ HCO3- by 1 –3

    mEq/L for each 10mmHg fall in PaCO2 

    Chronicrespiratoryacidosis

    ↑ PaCO2  ↓ pH  ↑ HCO3- by 4 mEq/L

    for each 10 mmHgrise in PaCO2 

    Chronicrespiratoryalkalosis

    ↓ PaCO2  ↑ pH  ↓ HCO3- by 2 –5

    mEq/L for each 10mmHg fall in PaCO2 

    Metabolicacidosis

    ↓ HCO3-  ↓ pH  ↓ PaCO2 by 1 to 1.5

    × fall in HCO3- 

    Metabolicalkalosis

    ↑ HCO3-  ↑ pH  ↑ PaCO2 by 0.25 –1

    × rise in HCO3- 

    Lumbar Tap OrdersPlease secure consent Prepare the ff materials:

    Sterile gloves size _____Disposable needle q 23/24Sterile Specimen bottles #4Eye sheetSterile gauze/cottonBetadine/Alcohol #1

    Secure ___________ for sedationFor HGT prior to LT

    Post Lumbar Tap Orders

    >Flat on bed for 4 hours>NPO temp for 2 hours then may feed oncefully awake with aspiration precaution>Monitor VS q 15 min x 1 hour, q30 mins x2 hours then q 1 till stable>Send CSF Specimen to the lab as ff:

    bottle #1 : GS/CS; AFB#2 : RBC, WBC, diff ct.#3 : protein/sugar#4 phadebact ( test for strep B, H. I influ, strep Pn, Nmeningitides)

    Blood transfusion Orders

      Secure and transfuse (blood product )to run for hoursproperly typed and x matched

      IVF to KVO while ongoing transfusion then

      Resume present IVF once transfusion is finished

      watch out for any untoward signs and symptoms such asfever, chills, rashes, DOB, tachycardia

      hook plain NSS while on BT to run at KVO

      monitor vs q 15 minutes while ongoing BT

      give paracetamol __ mg SIVP 1 hr prior to BT

      Inform PROD once blood product is available

      For repeat CBC 6 hours post BT (optional)

      Furosemide at 0.5- 1 mg/kg/dose mid

    For BMA Orders

      prepare the ff Materials

      gloves size_____

      eye sheet

      sterile cotton #1

      sterile gauze # 2

      glass slides #20

      syringe 10 cc #2

      5cc syringe #1

      betadine #1

      lidocaine 2% #2

      70% alcohol

      secure consent pls. and post BT (depends sa AP)

    For exchange transfusion ordersPls. prepare the following :

    -  French 5 feeding tube #2-  3 way stopcock-  syringe connector-  sterile bottle 1L-  10 cc syringe #2-  betadine and alcohol-  sterile cotton-  sterile gauze #2-  suture with needle

    note: give calcium gluconate 10%0.7 ml + 0.7 ml sterile water IVpush every 10 exchanges> give furosemide after exchange

    Pulse Cyclophosphamide Therapy( for Systemic Lupus Erythematosus)Pre hydration:- D5W 750 ml to run for 1 hour alternate with D5 0.3 Nacl 750 for 2 doses- Ondansetron (zafran) 8 mg/4ml, 4 mg +50 ml D5W to run for - cyclphophamide 1gm (1000 mg) + 100 ml D5W to run for 1 h

    Post chemo/ cyclophosphamide hydration- same regulation as pre chemo hydration- ondansetron 4mg + 50 ml D5W for 30mins- Prednisone 20 mg OD after breakfast- TPR q4 and record pls.- I and O q shift- limit sodium intake to 2 g/day- maintain on heplock after 10 hrs. therapy

    Materials for Triple Intrathecal (TIT)

    > NPO temp. For 4-6 hours> secure consent> prepare the ff. materials:

    - sterile gloves size_______- sterile eyesheet- sterile cotton balls- sterile gauze- sterile water 50 ml #1- tuberculin syringe #3- sterile specimen bottle #1- 2.5 cc syringe #1

    >sterile needle g 23 or ___

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     ACID PHOSPHATASE 

    (Major sources: prostate and erythrocytes)

    Newborn 7.4 –19.4 U/L 7.4 –19.4 U/L

    2 –13 yr 6.4 –15.2 U/L 6.4 –15.2 U/L

     Adult male 0.5 –11.0 U/L 0.5 –11.0 U/L

     Adult female 0.2 –9.5 U/L 0.2 –9.5 U/L

    ALANINE AMINOTRANSFERASE (ALT) 

    (Major sources: liver, skeletal muscle, and myocardium)

    Neonate/infant 13 –45U/L

    13 –45 U/L

     Adult male 10 –40U/L

    10 –40 U/L

     Adult female 7 –35 U/L 7 –35 U/L

    ALDOLASE 

    (Major sources: skeletal muscle and myocardium)

    10 –24 mo 3.4 –11.8 U/L 3.4 –11.8 U/L

    2 –16 yr 1.2 –8.8 U/L 1.2 –8.8 U/L

     Adult 1.7 –4.9 U/L 1.7 –4.9 U/L

    ALKALINE PHOSPHATASE 

    (Major sources: liver, bone, intestinal mucosa, placenta, andkidney)

    Infant 150 –420 U/L 150 –420 U/L

    2 –10 yr 100 –320 U/L 100 –320 U/L

     Adolescent males 100 –390 U/L 100 –390 U/L

     Adolescentfemales

    100 –320 U/L 100 –320 U/L

     Adult 30 –120 U/L 30 –120 U/L

    AMMONIA 

    (Heparinized venous specimen on ice analyzed within 30 min)

    Newborn 90 –150 μg/dL  64 –107 μmol/L 

    0 –2 wk 79 –129 μg/dL  56 –92 μmol/L 

    >1 mo 29 –70 μg/dL  21 –50 μmol/L 

     Adult 0 –50 μg/dL  0 –35.7 μmol/L 

    AMYLASE 

    (Major sources: pancreas, salivary glands, and ovaries)

    Newborn 5 –65 U/L 5 –65 U/L

     Adult 27 –131 U/L 27 –131 U/L

    ANTINUCLEAR ANTIBODY (ANA) 

    Not significant 1 :320

    Patterns with clinical correlation:

    Centromere—CREST

    Nucleolar —Scleroderma

    Homogeneous—SLE

    ANTISTREPTOLYSIN O TITER 

    (4-fold rise in paired serial specimens is significant)

    Preschool 19yr)

    7.35 –7.45

    90 –110 35 –45 22 –2

    BILIRUBIN (TOTAL) 

    Cord 

    Preterm

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    CREATININE (SERUM) 

    Cord 0.6 –1.2 mg/dL 53 –106 μmol/L 

    Newborn 0.3 –1.0 mg/dL 27 –88 μmol/L 

    Infant 0.2 –0.4 mg/dL 18 –35 μmol/L 

    Child 0.3 –0.7 mg/dL 27 –62 μmol/L  Adolescent 0.5 –1.0 mg/dL 44 –88 μmol/L 

    Man 0.7 –1.3 mg/dL 62 –115 μmol/L 

    Woman 0.6 –1.1 mg/dL 53 –97 μmol/L 

    ERYTHROCYTE SEDIMENTATION RATE (ESR) 

    Term neonate 0 –4 mm/hr

    Child 4 –20 mm/hr

     Adult (male) 1 –15 mm/hr

     Adult (female) 4 –25 mm/hr

    FERRITIN 

    Newborn 25 –200 ng/mL 20 –200 ng/mL

    1 mo 200 –600 ng/mL 200 –600 ng/mL

    2 –5 mo 50 –200 ng/mL 50 –200 ng/mL

    6 mo –15 yr 7 –140 ng/mL 7 –140 ng/mL Adult male 20 –250 ng/mL 20 –250 ng/mL

     Adult female 10 –120 ng/mL 10 –120 ng/mL

    FOLATE (SERUM) 

    Newborn 5 –65 ng/mL 11 –147 nmol/L

    Infant 15 –55 ng/mL 34 –125 nmol/L

    2 –16 yr 5 –21 ng/mL 11 –48 nmol/L

    >16 yr 3 –20 ng/mL 7 –45 nmol/L

    γ-GLUTAMYL TRANSFERASE (GGT) 

    (Major sources: liver [biliary tree] and kidney)

    Cord 19 –270 U/L 19 –270 U/L

    Preterm 56 –233 U/L 56 –233 U/L

    0 –3 wk 0 –130 U/L 0 –130 U/L

    3 wk –3 mo 4 –120 U/L 4 –120 U/L

    3 –12 mo boy 5 –65 U/L 5 –65 U/L3 –12 mo girl 5 –35 U/L 5 –35 U/L

    1 –15 yr 0 –23 U/L 0 –23 U/L

     Adult male 11 –50 U/L 11 –50 U/L

     Adult female 7 –32 U/L 7 –32 U/L

    GLUCOSE (SERUM) 

    Preterm 20 –60 mg/dL 1.1 –3.3 mmol/L

    Newborn, 1 day 50 –80 mg/dL 2.8 –4.5 mmol/L

    Child 60 –100 mg/dL 3.3 –5.6 mmol/L

    >16 yr 74 –106 mg/dL 4.1 –5.9 mmol/L

    HEMOGLOBIN A1 C  5.0 –7.5% total Hgb

     Adult 12 yr 2.7 –4.5 mg/dL 0.87 –1.45 mmol/L

    POTASSIUM 

    Newborn 3.7 –5.9 mEq/L 3.7 –5.9 mmol/L

    Infant 4.1 –5.3 mEq/L 4.1 –5.3 mmol/L

    Child 3.4 –4.7 mEq/L 3.4 –4.7 mmol/L

     Adult 3.5 –5.1 mEq/L 3.5 –5.1 mmol/L

    PREALBUMIN 

    Newborn 7 –39 mg/dL

    1 –6 mo 8 –34 mg/dL

    6 mo –4 yr 2 –36 mg/dL

    4 –6 yr 12 –30mg/dL

    6 –19 yr 12 –42

    mg/dL

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      ConventionalUnits 

    Sl Units 

    PYRUVATE  0.3 –0.9 mg/dL 0.03 –0.10 mmol/L

    RHEUMATOIDFACTOR