8
U. 5. DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE Plans for Survey Of TV Effect on Children Revealed Plans for a sel'ies of conferences l eading to research into the effect of television upon children were announced ecent ly by the then Secretary of Health, Education, and Welfare, Abraham Ribicoff, Jwior to his resignation. "We expect these conferences to outllirn research projects which will be designed to l)rovi<le great- er knowledge of the impact of television on children and to make this knowl edge available in a prac- tical way as material for consid- erat ion by those ha\'ing responsi - bility for the p1·esentation of tele- vision programs," Mr. Ribicoff said in announcing plans for the confe1·ences. Project Hoi l ed by NAB The project was hailed by the pFesident of the National Associa- tion of Broadcasters, LeRoy Col- lins, former Governor of Florida, who said: "We are pl eased to see the un- dertaking of such broadly based planning of research. The televi - sion industry welcom es the devel- opment of authoritative informa- tion regarding the effects of tele- Yision on childt'en which should prove helpful in serv ing their (See SURVEY. P~ye 8/ Jul y 31, 1962 Volume XIV, No. 15 Anthony Celebrezze Heads DH EW Succeeding Abraham A. Ribicoff President Kennedy con fers with Anthony J. Celebre: ne of Cleveland ( cent er ) and Abra h am A. Ribicoff ot t he White House followi ng his ap- pointment of Mr. Celebre: n:e as Secr eto ry of Health, Educotion, and Wel- fare to succeed Mr. Ribicoff who resigned to compoign for the Senote.- Wide World Phot o. President Kennedy's app:lintmcnt of Anthony J. Celebrezze, five- time Mayor of Cle,·eland, Ohio, aE Secretary of Health, Education, and Welfare, was confirmed by the Senate July 20. Mr. Celebrezze ~ucceeds Abra- ---- ---- ------- ham A. Ribicoff, former Governor or Connecticut, who resigned Ju ly 13 to become a candidate for nomi- nation to t he 1:. S. Senate from that State . Tn making the surprise an - nouncement of Mr. Celebrezze's appointn1ent July 14, the President said that he ". . . brings to my Cabinet a wealth of experience gained from having w o r k e d through the years with the prob- lems of people, particularly those in the areas of health, education and welfare. Gonzales and Co. Display Tennis Skill In Exhibition for NIH , NMC Patients "He therefore brings to this great Department," Mr. Kennedy added, "an intimate knowledge which will prove invaluable in making the Depm·tment an effec- tive instrument for the genernl welfare." Patients from the NJH Clinical Center joined patients from the near by Naval Medical Cen te r and other spectators in witnessing an exhibition of top-flight tennis on the courts of the Naval Medical Centfl' on Thursday, July 19. Participants in the 2-set exhi- bition match were Pancho Gon- zal es, former amateu1· tennis great and subsequent ly king of the pros, who pai,·ed with Pauline Betz Ad- die, for rn er women's national singles champion, against Gardner Mulloy, former U. S. Davis Cup star, and Allie Ritzenberg, pro of the nearby St. Albans Tennis Club. P laying in J )erf ect weather, the quartet displayed a brand of ten- n is t hat thew exclama tions and frequent applause from the gal- l ery. Mulloy and Ritzenberg, off to a fast sta1t, won the first two games and the fourth. With his competi- tiYe dander up, Gonzales t hen ap- plied the pressure, and backed by the flawl es playing of his blond partner, came from behind to win the fil'st set 8-6. Mull oy, the shot master, was steady throughout and at times Mr. Celebi·e zze has been promi- nent in Ohio politics since 1950, when he was elected to the State Senate. He was reelected in 1952, and while still serving in the Leg- islature he was elected Mayor of Cleveland in 1953. He was rc- electc<l in '55, '57 and '59, and in 1961 won an unprecedented fifth term. He is President of the United States Conference of M ayors and in 1958-59 was President of the (Se, CRf,F.RRF.Z7.E, Paye .i) N ATIONAL INSTITUTES OF HEALTH PUBLIC HEALTH SERVICE New NIH Division Begins Operation With 5 Branches The new Divisi on of Research Facilities and Resources com- menced operation July 15 under the direction of Dr. Frederick L. Stone, formerly Acting Chief of the D ivision of General Medical sciences, in a<'cordance with plans announced in April by Surgeon General L uther L. Terrv. ln addition to the Office of the Chief, the Division aonsist$ of five branches: the Health Resea1·ch Fa- cil ities Branch, headed by Dr. Francis L. Schmehl; the AJ1imal Resources Branch, headed by Dr. Willard H. Eyestone; the General Clinical Research Centers Branch, headed by Dr. Sam Silbergeld; the Special R e s e a r ch Resources Branch, headed by Dr. J. Harold U pton Brown; and the Gene1·al Re- search Support Grants Branch, whose head was to be announced later. Branches Transferred The functions and responsibili - ties of three previously existing· branches have been transferred to the new Division as follows: H ealth Research Facilities Branch, DRG, to Health Research Facilities Branch, DRFR; Regional Primate Research Centers Brru1ch, NHL to Animal Resources Branch, DRFR; and Clinical Res ear r h Centers Branch, DGMS, to General Clinical Research Centel'S Branch, DRFR. (See DI!' IS/ON, !'aye J) Concert by Morine Bond To Be Gi v en August 2 The third in this season's series of outdoor band concerts for Clini- cal Center patients will be given here on Thursday, August 2, at 7:30 p.m., by t he U. S. Marine Band. NIH employees, theil· families and friends ar e cordially invited. The concerts are held on the first floor tenace of the Clinical Cen- ter, east of the auditorium. In case of min, the CC au<litorium is used.

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Page 1: Plans for Survey Anthony Celebrezze Heads DH EW New NIH … · 2019-05-21 · Animal Resources Branch, DRFR; and Clinical Res ear r h Centers Branch, DGMS, to General Clinical Research

U. 5. DEPARTMENT OF

HEALTH. EDUCATION. AND WELFARE

Plans for Survey Of TV Effect on Children Revealed Plans for a sel'ies of conferences

leading to research into the effect of television upon children were announced 1·ecently by the then Secretary of Health, Education, and Welfare, Abraham Ribicoff, Jwior to his resignation.

"We expect these conferences to outllirn research projects which will be designed to l)rovi<le great­er knowledge of the impact of television on children and to make this knowledge available in a prac­tical way as material for consid­eration by those ha\'ing responsi­bility for the p1·esentation of tele­vision programs," Mr. Ribicoff said in announcing plans for the confe1·ences.

Project Hoiled by NAB The project was hailed by the

pFesident of the National Associa­tion of Broadcasters, LeRoy Col­lins, former Governor of Florida, who said:

"We are p leased to see the un­dertaking of such broadly based planning of research. The televi­sion industry welcomes the devel­opment of authoritative informa­tion regarding the effects of tele­Yision on childt'en which should prove helpful in serving their

(See SURVEY. P~ye 8/

July 31, 1962 Volume XIV, No. 15

Anthony Celebrezze Heads DH EW Succeeding Abraham A. Ribicoff

President Kennedy confers with Anthony J. Celebre:n e of Cleveland (center ) and Abra ham A. Ribicoff ot the White House following his ap­

pointment of Mr. Celebre:n:e as Secretory of Health, Educotion, and Wel­fare to s ucceed Mr. Ribicoff who resigned to compoign for the Senote.­Wide World Photo.

President Kennedy's app:lintmcnt of Anthony J. Celebrezze, five­time Mayor of Cle,·eland, Ohio, aE Secretary of Health, Education, and Welfare, was confirmed by the Senate July 20.

Mr. Celebrezze ~ucceeds Abra- --------------­ham A. Ribicoff, former Governor or Connecticut , who resigned July 13 to become a candidate for nomi­nation to t he 1:. S. Senate from that State.

Tn making the surprise an­nouncement of Mr. Celebrezze's

appointn1ent July 14, the President said that he ". . . brings to my Cabinet a wealth of experience gained from having w o r k e d through the years with the prob­lems of people, particularly those in the areas of health, education and welfare.

Gonzales and Co. Display Tennis Skill In Exhibition for NIH, NMC Patients

"He therefore brings to this great Department," Mr. Kennedy added, "an intimate knowledge which will prove invaluable in making the Depm·tment an effec­t ive instrument for the genernl welfare."

Patients from the NJH Clinical Center joined patients from the nearby Naval Medical Cen ter and other spectators in witnessing an exhibition of top-flight tennis on the courts of the Naval Medical Centfl' on Thursday, July 19.

Participants in the 2-set exhi­bition match were Pancho Gon­zales, former amateu1· tennis great and subsequently king of the pros, who pai,·ed with Pauline Betz Ad­die, for rn er women's national singles champion, against Gardner Mulloy, former U. S. Davis Cup star, and Allie Ritzenberg, pro of the nearby St. Albans Tennis Club.

P laying in J)erfect weather, the quartet displayed a brand of ten­nis that thew exclama tions and

frequent applause from the gal­lery.

Mulloy and Ritzenberg, off to a fast sta1t, won the first two games and the fourth. With his competi­tiYe dander up, Gonzales t hen ap­plied the pressure, and backed by the flawles playing of his blond partner, came from behind to win the fil'st set 8-6.

Mulloy, the shot master, was steady t hroughout and at times

Mr. Celebi·ezze has been promi­nent in Ohio politics since 1950, when he was elected to the State Senate. He was reelected in 1952, and while still serving in the Leg­islature he was elected Mayor of Cleveland in 1953. He was rc­electc<l in '55, '57 and '59, and in 1961 won an unprecedented fifth term.

He is President of the United States Conference of Mayors and in 1958-59 was President of the

(Se, CRf,F.RRF.Z7.E, Paye .i)

N ATIONAL INSTITUTES OF HEALTH

PUBLIC HEALTH SERVICE

New NIH Division Begins Operation With 5 Branches The new Division of Research

Facilities and Resources com­menced operation July 15 under the direction of Dr. Frederick L. Stone, formerly Acting Chief of the Division of General Medical sciences, in a<'cordance with plans announced in April by Surgeon General L uther L. Terrv.

ln addition to the Office of the Chief, the Division aonsist$ of five branches: the Health Resea1·ch Fa­cilities Branch, headed by Dr. Francis L. Schmehl; the AJ1imal Resources Branch, headed by Dr. Willard H. Eyestone; the General Clinical Research Centers Branch, headed by Dr. Sam Silbergeld; the Special R e s e a r ch Resources Branch, headed by Dr. J. Harold Upton Brown; and the Gene1·al Re­search Support Grants Branch, whose head was to be announced later.

Branches Transferred

The functions and responsibili ­ties of three previously existing· branches have been transferred to the new Division as follows: Health Research Facilities Branch, DRG, to Health Research Facilities Branch, DRFR; Regional Primate Research Centers Brru1ch, NHL to Animal Resources Branch, DRFR; and Clinical Res ear r h Centers Branch, DGMS, to General Clinical Research Centel'S Branch, DRFR.

(See DI!' IS/ON, !'aye J)

Conce rt by Morine Bond To Be Given August 2 The third in this season's series

of outdoor band concerts for Clini­cal Center patients will be given here on Thursday, August 2, at 7:30 p.m., by t he U. S. Marine Band.

NIH employees, theil· families and friends are cordially invited. The concerts are held on the first floor tenace of the Clinical Cen­ter, east of the auditorium. In case of min, the CC au<litorium is used.

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Page 2 July 31, 1962 THE NIH RECORD

~ II Published bi-weekly nt Bethesda. Md .• by the Public Information Section. Offiee of Rcsenrch Information, for the information of employees of the National Institutes of Health, principal research center of the Public lleallh Service, U. S. De1,artment of Health, Education, and Welfare.

Editor E. K. Stabler

Stoff Corresponde nts

Betty Slattery, NCI; Tony Anastasi, NHI; Kathryn Mains. NIAID; )lary Henley. :-,/lAl\lD; Marie Norris, NIDR; Lillie Bailey, NTMH; Pat l\lacPhcrson. NJ!\'Dll; Elsie Fahrenthold. CC: Fare Heil. DRS; H<.'lene Doying, DGMS; Dick Turlington, DRG; Jean Torgerson, DRS.

NEWS from PERSONNEL

SUMMER STUDENT EMPLOYEES

Several hundred students have temporarily swelled the ranks of NIH employees again this summel'. The annual influx began in early June, and now nearly 500 high school, college, and professional school students are "on board" and functioning in a wide variety of positions in the professional, tech­nical and clerical areas.

Three hundred and twenty-two students are working in scientific and technical fields, and 114 are in clel'ical and related positions. In addition, 51 students are serving in the Commissioned OfTicer Student Training Extern Program (COS­TEP).

Fosters Student Interest

The summer employment pro­gram is designed to aid NIH scien­tists and administrators in accom­plishing essential work, and to fos­ter th e interest of students in pur­suing a caree1· in medical research.

The Pers o n n e I Management Brnnch has announced that this year two questionnaires in rela­tion to the summe1· program will be distributed-one to supervisors and one to students. These ques­tionnaires are designed to assist in an evaluation of the over-al\ ef­fectiveness of the summer pro­gram and will be used as the basis for effecting changes in next year's program.

MANAGEMEKT INTERN PROGRAM

Kenneth Brown, Executh·e Of­ficer, NIAID, and Chairman of the NIH Administrati"e T r a i n i n g Committee, bas announced that the recruitment of nine new manage­ment interns dul'ing the month of June hPs increased the numbe1· of interns cunently undergoing train­ing to 20-the largest group in the history of the program.

Mr. Brown said that the commit-

NMC Advises NIH Drivers To Observe Parking Rules

KIH employees who visit the Naval Medical Center are ad­vised by its Security Officer to carefully observe parking regu­lations.

It has been noted lately, he said, that many cars bearing NIH parking stickers have been parked in spaces reserved for Navy personnel.

The Security Officer said that unless N lH employees pa1·k in Yisitors' spaces, he will have to prohibit them from parkjng on the Navy reservation.

tee hopes no\\· to graduate this number annually, with no relaxa­tion of the high selection stand­ards which have always been main­tained.

Since its inception in late 1956, the management intern program has graduated a total of 30 young administrators, many of whom haYe now risen to positions of con­siderable responsib'lity a nd im­portance within NTH.

Mr. Brown added that the intcm program is proYing to be an in­valuable tool for staffing entrance level positions in general aclminis­trntion and in fulfi !ling many cen­tral service needs. The program has lately assumed international significance \\'ith four graduate in­terns now serving as administra­tive officers in Ghana, Brazil, Paki­stan, and France. A fifth gradu­ate is scheduled to leave for Tokyo in the autumn or early wi·nter.

M1·. Brown said that the Train­ing Committee expects that, with the continued expansion o( NIH and its prog1·ams, the intem pro­gram will become increasingly im­portant during the coming years.

Information on acquiring the services of an intern, either on a permanent basis or for a trainee assignment, may be obtained from the Employee Development Sec­tion, Person n e I Managemen~ Bnmch, Ext. 2147.

Mr. Clown, Balloons, Pennants Enliven Picnic for the CC Children Patients

About 30 Clinical Center children patients participated in their first NIH outdoor picnic on the afternoon of July 13 in the beautiful shaded area we~t of Building 20. Brightly colored banners strung between trees, and balloons for eYeryone added a festive note to The indiYidually packaged picnic the scene. fare consisted of sandwiches, eel-

Antics by "Mi·. Clown," as the children called him, were the en­tertainment hit of the picnic. He is Mr. Joseph Sliva of 515 Quincy Street, Washing-ton, who belongs to an amateur group known as Clovms, Incorporated, whose mem­bers devote their spare time to the entertainment of others.

The children also particpated in a variety of games, and there were prizes -for winners of the relay races.

ery and carrot sticks, potato chips, cookjes, and fresh fruit, prepared by the CC Nutrition Depal'tment, and included lemonade aplenty.

Normal volunteers and Junior Red Cross workers, assigned to the CC by the Gray Ladies of the American Red Cross, assisted Kristen Peery of the CC Patient Activities Section in making this first picnic a memorable affair for the children.

At the picnic for children patients of the Clillicol Center, a clown pro­vides e ntertainment and balloons add color. Left to right: Frank Suite of Brussels, Be lgium; Sharon A. Whitener of Silver Spring, Md.; Roderick M. Stotler of Greenbelt , Md.; Joseph Sliva of Washington, D. C. , os "Mr. Clown"; and Dovid Schuler of Parma, Ohio.-Photo by Sam Silvermon.

4 NIH Training Films Available from CDC Foul' training films prepared by for assessing the condition of the

or fol' the National Institutes of nervous system at birth, and pre­Health are available for loan to sents some oC the normal and ab­

normal 1·esponses lo these tests. merlical schools and other appro- Neurological Examination of the priate audiences. They are: One Yea1· Old - 16 mm, color,

Eaton Agent Pneumonia - 16 sound, 30 minutes, illustrates simi ­mm, color, sound, 22 minutes, de- lar techniques for use with this picts studies which confirmed the age group. role of the Eaton agent in primary All of the films are avai\ablc atypical pneumonia. from the Audio Visual Section,

Germfree Animals in Medical Communicable Disease Cente1·, Research-16 mm, colo1·, sound, 19 Public Health Service, Atlanta 22, minutes, shows the kinds of equip- Ga. Requests for loans should rnent necessa1·y to cany on germ- reach CDC at leaRt two weeks in free 1·csea1·ch and demonstrates the . ndvancE> of the p1·efened showing usefulness of gel'mfree animals as !date. Loans a1-e for short periods, research tools; techniques are ex- :not to exceed one week. The two plained. I neurological films are also ,:ivail-

Neurolo~cal Examination of the ,able from the American Medical Newborn-16 mm, color, sound, 30 Association Film Library, 535 minutes, depicts testing methods :Korth Dearborn St., Chicago, Tll.

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THE NIH RECORD

N IAI D Parasitologist Heads Advisory T earn In WHO Assignment Dr. Louis J . Olivier, Assistant

Chief of the NlAJD Laboratory of Parasitic Diseases and R ead of the Ecology, Biology and Field Studies Section, has accepted a 2-year tem­porary assignment with the WHO.

Tomorrow he will assume his new duties as T eam Leade1· of the Bilharziasis Advisory Team. Based in Geneva, Dr. Ol ivier will travel in wo.-ld areas where bilhar ziasis (schistosomiasis) is a problem.

Worldwide, schislosomiasis is one of the most serious disease problems, ranking next to malaria in importance. An estimated 150 million people in tropical a nd sub­tropical countries suffer from this debilitating pai-asitic disease.

Se rves in South America

A Commissioned Officer in the Public Health Ser\·ice, Dr. Olivier has been at the N IH since 1946 Tn the early 1950's he was sta­tioned in South America on as­signment to the Pan American Sanitary bureau while a staff member of the Laboratory of Tropical Diseases. He relurned to Bethesda in 1954. When the Lab­oratory of Parasitir Diseases was organized in 1959 he transfened to t hat unit.

DT. Olivier has t1·aveled exten­sively for t he WHO. In J a nuary 1961 at the request of the Indian government h e made a survey of foci of schistosomiasis in t hat country, and early this year spent two months in Trinidad, British Guiana, Venezuela, and Brazil studying the disease in those coun­lries.

At t he end of his ViHO assign­ment Dr. Olivier will return to the Laboratory of Parnsitic Di~ease!..

CELEBREZZE (Contin,u,d f rom Paye 1 J

American Municipal Association. 1n 1959 he was appoil1ted by Pres­ident Eisenhowe1· to the Advisory Commission on IntergoYernmental Relations and was reappointed earlier this year.

The son of naturalized American citizens, Mr. Celebrezze was bm·n in 1910 in Anzi, Italy, while his parents "·ere visiting their home­land. Although born in ltaly, he is by birth an American citizen, as h is parents made their home in Cleveland.

He was educated in Cleveland public schools and for a short time attended ,John Canoll University, also in Cleveland. He received his LL.B. degree from Ohio Northern University at Ada, Ohio, in 1936 and in the same vcar was admitted to t he Ohio B;ir.·

From 1937 until 1939, when he

July 31, 1962 Page 3

NEW 'COs' MEET AT COFFEE BREAK Dr. Kety Resigns Post at Hopkins To Return to NIH Dr. Seymom Kety, for the past

year Henry Phipps, Professor and Chairman, Department of Psychi­atry, J ohns Hopkins University School of Medicine, has returned to the N.ition:,l Tnstitutc of Mental

During a coffee break be tween sessions of the recent orientation pro-9,am conducted here, new PHS Commissioned Officers get acquainted with each other and meet NIH staff ,members.- Photo by Sam Silverman.

Health as Chief of t h e Labora­toi·y f r o m 1956 until he accepted the Hopkins ap­pointment I as t year.

Correlation Seen Between FFA Levels, Structure of Norepinephri ne Analogues

In announcing his return, D r . Robert H. Felix, Institute Direc-

Recent studies of analogues of norepinephrine show thei1· effect on free fatty acid ( FF A ) mobiliza­tion in many depends on their chemical structure at specific mole­cular sites. A correlation was not found between chemical structure and blood glucose level.

'l'he changes in plasma FF A and blood glucose levels during the in­fusion of ten analogues of noni­pinephl"ine, a I 1 sympatomimetic a mines, we1·e studied by Peter S. Mueller, Laboratory of Clinical Science, Xational Institute of Men­tal Health, and DaYid Horwitz, Ex­perimental Therapeutics Branch, National Heart Institute, to deter­mil1e those specific molecular stn1ctures and sites associated with changes in the p lasma FFA level in man.

N ine males, nonobcsc, 1101 mal volunteel's r eceived infusions of the amines, structural derivatives of phenylethylamine, in doses pro­ducing equivalenl bloo::l pressure

entered private law practice in Cleveland, he was an attorney for the Ohio Bureau of Unemployment Compensation.

During Wo.-ld War IT hP was a seaman in the U nited States Navy.

Mr. Celebrezze is married to the former Anne Marco of CleYela nd and has thrne children: a son, An­~hony, Jr., a first classman at the U. S. Naval Academy at Annapo­lis; and t"·o daughiel"s, Jean Anne and Susan Marie.

;\l[r. Ribicoff was the first mem­ber appoil1ted to Mr. Kennedy's Cabinet and the first to resign. In '.l farewell memol"andum to all DHEW employees he s~id, "The one and one-half years I have been .issociated with you has been one of the most memorable experiences of my life. I am very proud of this Department and of the people who work for it .. .. You have my thanks, deep appreciation and re­spect for all that you have done."

changes. The changes in FFA levels, glucose levels and hear t rate were r ecorded and compared with the change which occurred after a similar infusion of saline solution.

Fl'Om their observations the in­vestigators showed t he fatty acid effect depended upon th e presence of particular chemical groups at predetermined sites on th e amine molecule. They demonstrnted that the change in plasma FF A level does not always correlate with t he effect of blood glucose level or with physiological changes such as blood pressure and pulse rate. No consistent differences in effect was noted between those amines with predominant constl'ictor and t hose with predominant dilator effects on blood vessels.

This systematic study of the ability of the analogues of no1·c­pinephrine to mobilize FF A and blood glucose in man \\"as reported in the Journal of Lipid Research.

Three Exec. Secretaries Appointed by DRG

tor, said, "We Dr. Kety

are delighted to have him back at NIMH and look forward to the re­establishment of his association with us which has resulted in so much productive 1·esea1·ch."

As Laboratory Chief, Dr. Kety will be responsible for the dii-ec­tion of an NIMH progJ"am investi­gating t he biological aspects of schizophrenia.

Joins NIH in 1951

With the exception of hi,; year at Johns Hopkins, Dr. Kety has been with NTH since 1951, when he was named first Scientific Di­rector of the National Institute of Mental Health and the National Instit ute of Neurological Diseases and Blindness, a post he held for six years.

A physiologist, Dt·. Kety has sought an understanding of ho\\' the processes of the mind a1·e in­fluenced by the structure and func­tion of t he brain.

He first became widely known for developing a method of meas­uring cerebral circulation and oxygen consumption in the human

Dr. Dale R. Lindsay, Chief of brain. This finding led to new the Division of Research Grants, possibilities for studying brain has announced the appointment of" cirulation in coma, anesthesia, and three study section execut ive sec- sleep and under varying conditions retaries. They are Drs. Irving A. of consciousn ess, including anxiety. Woods, J ohn C. Dalton, and Harold The more than 100 scientific J. Fournelle. papers of which he has been au-

Dr. Woods, Director of the Sup- thor or coaulhor have dealt chiefly porting Research Laboratory at w i th cerebral circulation and the U. S. Army Aberdeen Proving metabolism, and with the biologi­Ground, has been named Executive cal aspects of mental diseases. Secretary of the Bebavi.oral Sci- Among Dr. Kety's many honors ences Study Section. He succeeds (See I\ETY. !'au, 4)

Dr. Munay Abo111 who now heads a new DGMS program of grants in Chief of the new Special Projects the behavioral sciences. Branch of NHL

Dr. Dalton has been named Ex- Dr. Fournelle from the Environ-ecutive Secretary of the Metab o- mental Services Branch of DRS !ism Study Section. Before his has been appointed Executive Sec­NIH appointment, Dr. Dalton was retary of t he Microbiology Fellow­an associate professor of biology ships Review Section. He succeeds at the University of Buffalo in

I Dr. Irving Delappe who trans­

Buffalo, N. Y. He succeeds Dr. ferred to the Extramu1·al Pro­William H. Goldwater who is now grams Branch, NIAID.

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Page 4

Dr. Andres Appointed To Gerontology Post Dr. Reubin Andres has been ap­

pointed Assistant Chief o( the Gerontology Branch of the Na­tional Heart Institute. Prior to his appointment he was Assistant Chief of Medicine, Depa,·tment of M edicine of the Baltimore City Hospitals.

Dr. Andres will assist Dr. Nathan W. Shock, Gerontology C h i e f , in administering the Branch's broad programs of re­search i.nto the many problems of the aged. The Gerontology staff is located at the Baltimore City Hos­pitals.

Teaches at Hopkins

Dr. Andres was Assistant Phy­s1c1an, Out-Patient Department, Department of Medicine, at Johns Hopkins University from 1950 to 1958. He was instruct01· in the same department from 1955 to 1959, when he was appointed As­sistant Professor of Medicine there.

Born in Dallas, Texas, in 1923, Dr. Andres graduated from South­ern Methodist University and Bay­lor University College of Medicine. He received his M .D. degree from Southwestern Medical College in 1944. From 1945 to 1947 he served as a captain in the U.S. Army.

In 1952 D1·. Andres was named a Diplomate of the American Board of Internal Medicine. He is a member of the Ame1·ican Physio­logical Society, the American So­dety for Clinical Investigation, Sigma Xi.

KETY (Contin1ted from f'ane SJ

and awards is the Distinguished Se1·vice A ward of the Depa1·tment of Health, Education, and Welfare, presented to him in 1958. He de­livered the Academic Lecture at the Annual Meeting of the Ameri­can Psychiatric Association in 1961 and that same year was speaker for the Thomas William Salmon Lectures, presented an­nually in New York City. He was recently elected to the National Academy of Sciences.

A native of Philadelphia, Dr. K ety received his A.B. degree in 1936 and M.D. degree in 1940 from the University of Pennsylvania. After completing his intemship at Philadelphia General Hospital, he spent a year at Harvard Univer­sity on a National Research Coun­cil Fellowship in the Medical Sci­ences.

He joined the staff of the Uni­versity d Pennsylvania in 1943 as instructor in pharmacology and, after interim promotions to assist­ant and associate professor, was appointed professor of clinical

J uly 31, 1962

First Results of Birth Study Link Prematurity & Smok~ing

The first important ·results of t he nationwide long-rnnge collabora­tive Perinatal Research Project link prematurity, stillbirths, and brain damage with some previously unsuspected events of pregnancy and delivery.

'l'hese findings on the study, which is coordinated by the National Institute of Neurological Diseases and Blindness, were revealed re­cently by Dr. Richard L . Masland, NI KDB Director, at hem·ings be­fore Congressional appropriations subcommittees.

"Although these are preliminary findings of continuing research and therefore should be viewed with caution," Dr. Masland said, "they may prove to be promising leads for futul'e investigation."

Now in its fourth year, the col­laborative project has compiled data to the present time on more than 23,000 expectant mothers and 17,000 children enrolled at 15 par­ticipating medical centers. Anal­yses of these data have revealed the following eal'ly findings:

• Premature births- an imp ort­ant cause of brain damage and deaths - occur more frequently among mothers who smoke than among nonsmokers. ( I nf an t s weighing 2,500 grams or less were considered to be premature,) In addition, birthweight was found to be inversely proportional to the reported amount of smoking. These findings confirm the results of previous studies which have shown a relationship between ciga­rette smoking during pregnancy and p1·ematurity.

• More than 40 percent of a firoup of study infants diagnosed as abnwrnal at the 8-rnonth psy­chological examination had suf­fered from breathing difficulties at or soon after birth.

Tn addition, Dr. Masland re­pm'ted to Congress that individual investigators at the collaborating hospitals ha\'e published the fol­lowing findings of special related studies :

• In efforts to identify mothers who run a high risk of losing their babies, investigators confirmed the finding of a previous study that there is a close relationship be­tween fetal deaths and certain al­terations in the concentration of blood proteins of expectant moth-

physiology to the Graduate School of Medicine in 1948, a position he held until 1961.

Dr. Kety is a member of a num­ber of national and international scientific and professional societies and serves on the editorial boards of several scientific journals. H e is Editor-in-Chief of the Journal of Psychiatric Research, a new jour­nal published quarterly and devot­ed to the scientific aspects of psy­chiatry.

ers. These results may lead to the development of preventi\'e therapy.

• Additional evidence was un­covered to show that premature births may be caused by a symp­tomless urinarv tract infection which cannot b~ detected bv rou­tine methods. Scientists at ·one of the collaborating institutions have de"ised a simple, sensitive test fo1· detecting this infection.

• Investigators confirmed that infants of diabetic mothers weigh more than infants of nondiabetic mothers. However, postmortem studies showed that the brains of infants of diabetic mothers were comparatively sni.1ller in weight and volume.

• High rates of prematm·ity and infant death were found to be as­sociated with findings suggestive of inflammation of the placenta, fetal membrnnes, and umbilical cord. In some 50 percent of cases where such inflammation occurred, infection of the vagina, cervix, or both was also present, a discovery which emphasizes the impo1tance of careful treatment o( these in­f ections during pregnancy.

• Tn studying the effects of an Asian flu epidemic on pregnancy outcome, scientists 1·eported that this infection may affect the un­born child especially if it occurs <luring the early months of preg­nancy. Especially important was the discovery that nearly 40 per­<'ent of cases had no symptoms and could be cliagno~ed only by blood test.

• A possible basis for early de­tection of brain damage in young children was pro\.ided by studies showing that prolonged lack of oxygen is followed by an increase in the permeability of the blood­brnin banier to certain enzymes. Brain damage may then be diag­nosed by measuring the increase in these enzymes in the spinal fluid.

• Improved techniques were de­\'eloped at one of the collaboTati.:ng hospitals to detect bi·ain damage in infants by me a n s of brain wa\'e recordings (electroencephalo­grams). Moreover, the use of visual stimulation in conjunction with these recordings is providing criteria for determining brnin maturation at birth.

• A new pamphlet published by NINDB describes in detail the pur­pose and operation of the collabo­rative p1·oject. Single copies of the leaflet, "The Fateful Months

THE NIH RECORD

CC Chief of Pharmacy Elected to Presidency Of Pharmacy Society Milton vV. Skolaut, Chief of the

Clinical Centei· Pharmacy Depatt­ment, received notification on July 19 of his election, by mai led ballot, to the office of President of the American S o c i e ty of Hospital

Pharmacists for the 1 9 6 3 - 1964 term, beginning next May 1.

T h e Society, an affiliate of the American Phar­maceutical Asso­ciation, is a na­tional organiza­tion devoted to

Mr. Skolout lhe profession of hospital pharmacy and declicated to the improvement of pharmaceu­tica l service in the interest of bet­ter patient care in hospitals. Mem­bership n ow totals 3,400, including about 3,200 from t he United States and Canada and app1·oximately 200 from other countries thl'oughout the wol'ld.

Se rves an Committees

Mr. Skolaut was Vice President of the Society in 1955-1956. He has served on various committees and pm·ticipated in programs at most of the Society's annual meet­ings and institutes on hospital pharmacy. He is Chairman of t he Publicity Committee and the Reso­lutions Committee and a membe1· of the Executive Committee. The author of many articles published in the literature of the profession, he has presented various pharma­ceutical programs over closed cir­cu it te)e\·ision.

He is a contributing editor to the American Journal of Hospital Phai1nacy, the official journal of the American Society of Hospital Pharmacists; a consultant to the Saint Elizabelhs Hospital; and member of a number of profes­sional organizations.

Mr. Skolaut joined the Commis­sioned Corps of the Public Health Sen·ice in 1949 and now holds the rank of Pharmacist Directo1·. He is a g1·aduate of the University of Texas College of Pharmacy and served his intemship at the Johns Hopkins Hospital in Baltimore. He was with the PHS Hospital, Stat­en Island, N. Y., prior to assuming his present position in 1953 when the Clinical Center opened.

When Life Begins," are available from the N INDB lnfo1·mation Of­fice, Bldg. 31, Rm. 8A46, Ext. 5751. Multiple copies may be purchased from the Superintendent of Docu­ments, U. S. Government Printing Office, Washington 25, D. C., for five cents a single copy or 83.25 per l 00 copies.

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THE NIH RECORD Ju ly 31, 1962

Following their exhibition doubles match at the Novol Medical Center, the three male participants conduct a brief "post morte m" for the bene­fit of NIH Clinical Center patients (seated), four of whom are visible in this picture. The players, left to right : Pancho Gonxoles, Allie Rit:.en­berg, and Gordner Mulloy. Children ( right}, daughters of Novy per­sonnel, ore wait ing to request autogrophs.-Photos by Jerry Hecht.

Two PHS Scientists Win ACS Scholarships Two Public Health Service scien-

tists were awarded Postdoctoral Research Scholarships recently by the American Cancer Society,

These grants, two of four made in the country, are a new cate­gory of research grants aimed at preparing young physicians and cloctol's of philosophy for careers in clinical ill\·estigation of cancer.

Dr. Alexander L. Kisch, Senior Assistant Surgeon in the Labora­tory of Infectious Diseases, :I\ a­tional Institute of Allel'gy and In­fectious Diseases, recei,·e<l a 1-year scholarship of $10,140.

Studies in Scotland He will begin study at the In­

stitute of Virology, University of Glasgow, Scotland, later this sum­mer. Dr. Kisch received his M.D. degree from Harvard Medical School in 1956.

Dr. Lyman A. Page, Associate Director, Poison Contl·ol Branch, Bureau of State Services, received a 3-year S<"holarship of $36,190. He began study at Da1tmouth Col­lege Medical School, Hanover, N. H., on July 1.

Dr. Page, who is also a junior associate at Childl'en's Hospital, Washington, D. C., l'eceived his M.D. degree from Columbia Uni­versity College of Physicians and Surgeons in 1957.

TENNIS (Continued. f rom Pag(' 1)

brilliant, but Rihcnberg. obviously off his game, alternated between flub shots and spectaculal' play. Gonzales and Addie won the sec­ond set at 6-4.

Later the same day, in a match at St. Albans' courts, Mulloy and Ritzenberg got their revenge by defeating Pancho and Pauline in a 3-set match, 4-6, 8-6, 6-3.

The match at Navy was one of a series by the four players in the Washington area that week, in coopei-ation with the Sports Committee of the People to People Progrnm. Tt was refereed by H. L. Richards, former member of the U. S. Davis Cup Committee, now a resident of Lake Barcroft, Va.

Gonzales, now pro at the new Ocean Club on Paradise Island in the Bahamas, is also coach of th e U. S. Davis Cup team. Pauline Addie is now the pro at the nearby F,dgemoor Club.

These are th~ first of a new category of grants which seeks to cut down the lag bet,veen the re­search scientist's laboratory and the clinical application of the sci­entists' findings by practicing phy­sicians.

Pauline Bet:r; Addie, former U. S. Women's Singles Champion, is caught by the camera midway of a backhand kill at the net, during the e xhibi­tion match ot the Novol Medical Center. Her partner, GonJEoles, hovers in the bock court.

Page 5

This closeup of Poncho Gon,.oles, poised for o return at the net, reveals the tiptoe balance and steel-spring leg action that led sport swriters to dub him "the Big Cot."

DIVISION (Continued from Page J)

Responsibility for the adminis­tration of two p1·ograms previous­ly administei-ed by DGMS has been transferred to DRFR, as follows: General Research Suppo1t Grants to General Res ear ch Grants Branch, and Special Research Re­source Grants to Special Research Resoui·ccs Bl'anch.

-Prim· to ap11ointment to the new Division, Dr. Schmehl was Chief of the Health Research Facilities Brnnch, DRG; Dr. Eyestone was Chief of the Regional Primate Re­search Centers Branch, NHI; Dr. Silbergeld was Chief of the Clini­cal Research Centers Branch, DGMS; and Dr. Brown was Execu­tive Secretary of two DGMS Training Committees-Physiology and the Biomedical Engineering Training Program.

Gerald Sparer, Assistant Execu­tive Officer of th e PBS Division of Radiological Health, is the DRFR l~xecutive Officer; Helen Schroed­er, Chief of the Gi·ants Adminis­Lrntion Section, Research Training Bmnch, DGMS, has been named Special Assistant to Dr. Slone; and Herbert B. Nichols, Informa­tion Officer of DGMS, is the Infor­mation Officer of DRFR.

It is expected that all five branches of the Division will be lo­cated soon in the Plaza Building at t he corner of the Rockville Pike und Wall Lane.

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Page 6

USSR Congress Attended by 24 NCI Scientists Twenty-four members of the

staff of the :-I ational Cancer In­stitute were scheduled to present reports at the Eighth International Cancer Congress held at the Uni­versily of Moscow, July 22 through 28.

The International Union Against Cancer, a worldwide organization pl'omoting inlernational coopera­tion in tho fight against cancer, sponsored the meeting.

Presents Data

\Villiam Haenszcl, Chief of the Institute 's Biometry Branch, was chairman of a panel presenting the first data gathered under a new international program of coopera­tive cancer registries. Each of five representatives from countries participating in the program (England, France, Denmark, Fin­land, Norway, and the United States) planned to present an analysis of data on cancer of a s ingle site gathered from all six countries.

Dr. Sidney J. Cutlet·, Head of the Clinical Biometry Section of the Biometry Branch, was sched­uled to report data from the six partidpating nations on cancer of the large intestine. l{eports were also given on leukemia and cancer of the tongue, breast, and t estis.

Speakers listed

KCI scientists planned to speak on four of the other fourteen panel discussions at the Congress. They a1·e: Dr. Harold L. Stewart, Chief of the Pathologic Anatomy Branch, a panelis t on the Etiology and Pathogenesis of Cancer; Dr. Al­bert ,/. Dalton, Head of t he Cellu­lat· Biology Seclion of the Labora­tory of Vin,! Oncology, a panelist on the Ultrastructure of Malignant Cells; Dr. Paul Kotin, Chief of the Carcinogenesis Studies B1·anch, who planned to speak on air pol­lution by cancel'igenic substances on the panel on Cancerigenic Sub­stances in Human Environment; and Dr. Sarah Stewart of the Lab­oratory of Virnl Oncology, who was scheduled to report on polyoma vil-us on the Viruses and Cancer Panel.

Eighteen NCI scientists were scheduled to present original pa­pers on various aspects of t he can­cer problems. They are: Dr. J . Robert Andrews, Chief, Radiatiou Branch; Dr. Walter E. Heston. Chief, Laboratory of Biology; Dr. John Weisburger, Carcinogenesis Studies Branch; D1·. Julius White, Chief, Laboratory of Physiology;

July 31, 1962 THE :--/ Ill HECORD

NINDB Scientists Share 'Fight for Sight' Award The second annual "Fight for

Sight" citation has been presented to Dr. Sjoerd L. Bonting, Head of the Section on Cell Biology, Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, and his associate, Dr. Kenneth A. Simon, for their paper, "Sodium-Potassium Acti­vated Adenosine Triphosphatase and Aqueous Hun101· Fmmation."

The award, which consists of $500 and a sc1·oll, was pi-esented by the National Council tu Combat Blindness, Inc., at an awards din­ner on June 26.

The citation, which was also awarded to NINDB scientists last year, is presenter! for the most significant paper given at section­al meetings of the Association for Research in Ophthalmology.

The report presented by Drs. Simon and Bonting will be pub­lished this summer in Experi­mental Eye Research and the Ar­chives of Ophthalmology.

Dr. W ilhelm C. Huepe1·, Head, En­\·ironmental Cancer Section; Drs. Jolm B. Moloney and Frank J, Rauscher, Jr., Laboratory of Viral Oncology; Dr. Thelma B. Dunn, Dr. Roget· W. O'Gara, Dt·. Kath­erine :M. Herrold, and Willie D. Morgan, Laboratory of Pathology.

Also Dr. Abraham Goldin, Lab­oratory of Chemical Phannacol­ogy; Dr . Harold P. Morris, Dr. Helen M. Uyer, Ur. Pietro M. Gul­lino, and Jehu C. Hunter, Labora­tory of Biochemistry; Dr. Harry V. Gelboin, Diagnostic Research Branch; and D1·. Paul P. Carbone, Medicine B1·anch. A former mem­ber of the lnstitute's staff who is now Directot· of the National Insti­tutes of Health West Africa Re­search Unit-Ghana, Dr. J ohn H. Edgcomb, also planned to present a paper at the C011gress.

Abstracts Published

Abstrncts of papers by Drs Maurice Landy, Laboratory of Chemical Phannocology; William Moh\et', Medicine Bl'anch; and Lloyd W. Law, Laborato1-y of Biol­ogy, will be printed in the oflicial Congress proceedings.

Othcl' membc1·s of the NCI staff who were scheduled to attend are: Dr. Michael B. Shin1kin, A~sociate Di,·ecl<>r [01· Field Studies; Dr. l\farga,·el H. Sloan, Special Assist­,mt to the Director; Dr. Murray J. Shea,·, Ch ie f, Laboratory of Chemical Pharmacology; Dr. O. Malcolm Ray, Deputy Chief, Re­search G rants Branch; Dr. Herbert J. Rapp, Head of the Tmmunolog:v Section of thCl Diai>;nostic Research Branch; Dr. Margaret G. Kelly. Medicine Branch; Dr. "Elizabeth K. Weisburger, Carc·inogenesis Stud­ies Branch; and Dr. Flo,·ence R

Sorority Gives Award To CC Dietetics Chief Edith J ones, Chief of the Nu­

trition Depa-rtment of the Clinical Cenler, received the Alpha Chi Omega Award of Aehievement in the field of dietetics at the final banquet of the sorority's national

Miss Jones

convention, held recently in Miami Beach, Fla.

The Award of Achievement, es­tablished in 1955, is given to alum­nae members who have distin­guished I, hem -selYes i11 their c h o s en fields.

This is the third such honor Miss J onci; has receh·ed during her Clinical Centet· tenure, which be­gan in l 953 when th<' Center opened.

In 1957 the Association of Mil i­tary Surgeons presented her with the McLester Award for distin­guished service in the field of ap­plied nutrition and dietetics, and she received a Distinguished Serv­ice Awarrl from the University of Alabama in 1956 "for pl'Ofesgiona\ leadership in dietetics and excep­tional ability in organizing hos• pita! dietary departments."

Graduates with Honors

A graduate \,·ith honors from lhe University of Alabama and an i11iLiate of the Alpha Chi Chapter there, Miss Jones received hei- M.S. degree, also with honots, from the Uni,·ersity of Tennessee, and com­pleted d ietet ic intemship at Johns Hopkins Hospital in Baltimore.

During World War U she gained experience in therapeu· ic and administl·ative dietetics in Army hospitals in both the United Stales and the European Theult-e.

Miss Jones joined the Commis­sioned Corps of the Public Health Senice in 1950 and was assigned to the Bui·eau of State Services prior to her appointment here.

She is active in a number or professional organizations in the field of nutrition, and is now President-elect of the American Dietetic Association. She will as­sume this office in October at the annual meeting in Miami.

White. Research Communications Branch. Dr. Ray is the only mem­ber from the U.S.A. on the I.U. A.C. Committee on Tnternatio11a' Congresses. Dr . Shear is Chair-

CC Investigators Need Referrals of Patients For 2 Current Studies Clinical investigators at the

Clinical Center are requesting the coope1·ation of physicians. They need referrals of patients with Reiter's syndrome and chronic­myelogenous leukemia for cuxrent studies.

Renewed efforts are being made to recover and identifv the causa­li\·e agent of Reiter'~ syndrome. The sylldrome is characterized by a triad of arthritis, urethritis, and conjunctivitis. Cases lacking con­junctivitis would still qualify for this study. The presence of gono­coccus and urethral discharge would not preclude acceptance of a case p1·ovided this organism is not present in the synovi,i 1 fluid.

Confirms Diagnosis The appearance of cutaneous

manifestations (balantitis, kerato­de r111ia bl en not 1·hagica, maculopap­ula,· eruption on penis, hard pa­pules on soles) help confirm the diagnosis. Reiter's syndrome lasts for an average of six weeks and recurs in about 50 perce11t of the cases.

Most desirable are cases within the first two weeks of onset. Ac­cepted patients will be studied for several weeks. Upon completion of study, patients will be returned to the ca,·e of their refening physi­cians \\'hO will receive a complete narrative summary.

Physicians wishing to have pa­Lienls considered for this study may \\'rite or telephone Dr. Joseph J. Bunim, Clinical Director, Na­tional Institute of Arthritis and Metabolic Diseases, Bethesda 14, Md. Telephone: 496-4181 (Area code :301).

Studies Leukemia The study of chronic myelo­

genous leukemia, conducted by the Chemolherapy Service of the Na­tional Cancer Institute, 1·equil-es, particularly, patients in the 20 to 10 age group with high white blood cell and platelet counts for studies of newer chemotherapeutic agents and a source of white cells and platelets for iu vi/J ·o and in vivo studies. Physicians wishing to r efer patients with this disease may \l'l'ite or lelephonP Dr. Paul 8. Carbone, National Ca1wer In­stitute, Bethesda 14, Md. Tele­phone: 496-4251 (Area code 301).

man of the l.U.A.C. Finance Com- tees to work on such problems as mittee and the Committee 0~1 tumor nomenclature, and stimu­Chemothe1·apy. ]ates and encourages national ef-

The International Union Against fmts in 1·esearch, therapy, and con­Cancer sponsors international con- ti-ol. It is affiliated with the Wor'd ~resses every four years. 'l'he cil for lntemational Organizations Union a lso publishes an interna- Health Organization and the Coun­tional journal, establishes commit- of Medical Sciences.

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THE N IB RECORD

ARC Youth Group Aids In Patient Activities This summe,· for the first tirrw,

Gray Ladies oI the American Red Cross on duty at the Clinical Cen­ter have me~bers of the Red Cross youth g1·oup to assist them with their volunteer se1·vices.

Twenty-five of the 60 teenagers who 1 ecently completed the Mont­gomery County Red Crnss training courses for volunteer sen·ices are now assigned to the Gray Ladies Office of the Clinical Center for duties in the Patient ActiYities Section.

Four of the group are serving as assistants in the Patients Library, and the others are assisting with recreational activities arranged for both children and adult patients.

Amold Sperling, Chief of the CC Patient Activities Section, reports that these young people are doing outstanding work. "I am de­lighted," he said, "to have them here for the summer months when many outdoor events are being p lanned for the patients."

Surgeon General Names Dr. Wall ace Lane Chan To Investigations Post Dr. Wallace Lane Chan of the

immediate OfTice of the Surgeon General has been named Director of Investigations fol' the Public Health Service, Surgeon General Luther L. Teny announced re­cently.

Dr. Chan and his staff will be 1·esponsible for receiving, investi­gating, and making recommenda­tions with regard to grievances which, in the opinion of the em­ployee concerned, cannot be prop­e l'ly handled undel' established procedures.

Still in effect will be the estab­lished p1·ocedures for both Ci,·il Service and Commissioned Officer personnel for dealing with com­plaints about conditions of employ­ment, promotions ol' demotions, re­ductions h1 force, and similar mat­ters.

Report s Directly The Director of Investigations

will report directly to the Surgeon General.

A native of San Francisco ann a 1952 graduate of the Stanford University School of Medicine, Dr. Chan has had extensive expedence with several Fede,·al Gon, rnment agencies.

He has se1Ted on the medical faculties of Stanford University and George Washington Unive1·­sity, and as medical director of private research organi:,mtions. He comes to his 11ew position from an assignment as Special Assistant to the Deputy Sui·geon General, Pub­lic Health Services.

July 31, 1962

These teeenagers, now assisting in the Patients Library of the Clinical Center, were members of o class of 60 who recently completed the Montgomery County Red Cross tra ining course for volunteer service. They ore pictured outside the Chapter House following the groduat:on ceremony. Students at Walte r Johnson High School, Bethesda, they are ( left to right ) : Donald Edwards, Ting Ho, Karen Jenne, and Thomas Duvall.-Red Cross Photo by David Noche.

Environment and Cance r Not Linked in Study The National Cancer Institute

has completed a detailed study of causative environmental factors in cancer in the Hagerstown area of Maryland, but will continue to ob ­serve evidence of geographical or family clustering of cases ou a population-wide basis.

The studies recently concluded were started about five yeal'S ago in 20 election districts of Washing­ton County. They combined lab­oratory analyses of soil, rocks, "·a­te1·, air and vegetation with a re­view of county health 1·ecords dat­ing back se,·eral score of yem·s and the gathering of uew information on cancer illness in the study area.

An analysis of the mortality rates from al l causes of cancer onr a 30-year period in each of the 20 election districts showe::l that, contrary to p1·evious imp1·es­sions, the variation in the rates from one district to another was

Six Psychotropic Drugs Studied for Effects On V MA Excretion A National Institute of Mental

Health study of the effects of six psychotropic drugs on urinary ex­cretion of vanillylmandelic acid (VMA). show that only two caused changes in VMA excretion, indicating altered catecholamine metabolism.

The study was made by Dr. Roger K. McDonald and Virginia Weise, Laboratory of Clinical Sci­ences, NJMH, using a highly spe­cific method developed by these in­vestigators.

The six drugs consisted of three tranquilizers, reserpine, chlorpro­mazine and meprobamate; a nar­cotic, morphine sulfate; a hyp­notic, pentobarbital sodium; and a cerebral stimulant, d-amph0tamine sulfate.

attributable to chance and could Affects Excretion not be correlated with specific en- Administration of these drugs vironmental conditions. These de- in single doses to 16 normal vol­tailed studies have therefore been untee1·s at NIH, re,·ealed that only discontinued, and in the future, two, reserpine and chlorpromazine, cluste1-ing of cases by family or were associated with a consistent geographic area will be given in- and unequivOl'al effect on VMA tensive study to relate cancer to excretion. Reserpine caused an in­environment. crease and chlorpromazine, a de-

The laboratory "·ork has been crease in VMA excretion. These conducted in a building donated to effects were indeper:dent of any the W;;rnhington County He;ilth related change in kidney function Department by Andrew K. Coif- as detennined by endogenous man of Hagerstown. A staff of creatinine excretion. six National Cancel' Institute em- Morphine sulfate <·aused a de­ployees will remain in this build- r1·ease in VMA excretion followed ing to continue the field studies. by an increase. These ch,mges,

Other divisions of the Pub1ic how e v er , were paralleled by Health Service will now share the changes in endogenous crcatinine resources of the p1·oject for studies excretion indicating the effect of on different disease !Jl'oblems. I morphine on VMA excretion was

Page 7

Stanford Institute Gets Grant to Study Virus Relationship to Cancer The Public Health Service has

announced the award of a $99,459 contract to the Stanford Research Institute, Menlo Park, Calif., for l'esearch which may provide new clues to the possible causative 1·e­lationship of viruses to human cancer.

Studies will be conducted to de­termine whether virnses play a role in the development of breast cancer in rats after exposure to a chemical known to cause this type of tumor.

Dr. Kenneth l\'I. Endicott, Di­rector of the National Cancer In­stitute which will administ,;\r the contrnct, said that recent advances in laboratory techniques and rap­idly accumulating knowledge of animal tumor viruses should make this research more fruitful than was possible heretofore.

Dire cts Project Dr. Jean Scholer, Chairman of

the Department of Experimental Therapeutics, Stanfotd Research Institute, has been named project director. He1· approach will be to administer a single oral dose of 7, 12 dimethylbenz (a) anthracene (DMBA) to rats and await the de­velopment of tumors.

By the technique of ultracentri­fugation (based on a new method developed recently by National Cance1· Institute scientists) ex­tracts of tu mo1· or other tissues will be spun at high speeds, re­sulting in concentration of any \'iral agents that may be present. Newborn rats will be inoculated with the pellet thus producer! and observed over a period of one year for the de.-elopment of tumors.

Attempts also will be made in a similal' manner to demonsln.1te the presence of cance1·-causing viruses in tissues of DMBA-treated ani­mals prior to the appearance of tumors.

not a manifestation of altered catecholamine metabolism.

'l'hrough measurement of uri­nary tryptamine excretion, t hese investigators have shown that cl-amphetamine causes no mona­mine oxidase inhibition, thus dis­proving a widely held theory that this is the mechanism by which ,imphetamine c a u s e s cerebral stimulation.

1n conclusion it is evident that there is no consistent relationship between the rate of catechola­mine metabolism and the observed clinical effects of the psychotropic rll'ugs tested.

These findings are reported in The Journal of Pharmacology and Experimental Therapeutics.

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Page 8

SURVEY (Co11ti111.ted /rott, Page I J

needs and interests. Our associa­tion stands ready to assist in whate,·er ways it can."

Preceding actual research will be planning conferences, spon­sored by HEW and paTticipated in by professional educators, special­ists in child welfare, mass commu­nications reseai·chers, and ,·epre­sentatives of the television indus­try.

Purposes of these conferences are:

• To devise ways of conducting research on this subject.

• To recommend specific re­search projects on the rela­tionship of television to chil­dren.

• 'l'o recommend research proj­ects that would be of aid to the television industry in its exploration of techniques to be used in programs for chil­dren.

Directing the planning confer­ences will be a steering committee, under the chairmanship of Be1·­n ard Russell, Deputy Special As­sistant to Secreta1y Ribicoff, and consisting also of the following representatives of education and television:

Howard H. Bell, Vice President for industry affairs, National As­sociation of Broadcasters; Hugh M. Beville, Jr., Vice President for planning and research, National Broadcasting Company; Giraud Chester, Vice President in charge of daytime p1·ogramming, Ameri­("an Broadcasting Company televi­sion network; Dr. Ralph Garry, College of Education, Boston Uni­Yersity; Donald H. McGannon, President, Westinghouse Broad­casting Company, and Frank Shakespeake, Vke President and Assistant to the President, Co­lumbia Broadcasting System tele­Yision netwo1·k.

This steering committee will meet sho1-tly to prepare the sched­ule and invite participants fo1• the planning conferences, which are expected to be held early this fall.

The Foundation for Character Education will contribute .Cunds an rl services to the planning con­ferences. HEW will publish re­sults of the conference.

Financing for or sponsorship of research growing out of the plan­ning conferences may be under­taken by a number of different or­ga11 izations.

The project originated from a recommendation bv Senato1· Thom­as J. Dodd of Connecticut, sug­gested by Govemor Collins during the course of hearings held by Senator Dodd's subcommittee on jU\·enile delinquency, that the Secretary of Health, Education, and Welfare sponsor the planning of research.

Commenting on the project, Sec­retary Ribicoff said:

July 31, 1962

I RML EMPLOYEES WIN CASH AWARDS I l "

Three employees of NIAIO's Rocky Mountain Laboratory at Hamilton, Mont., who won cash awards for Be ne ficial Suggestions ore pictured at a recent informal awards ceremony at the RML. George Tallent, o physical science technician (second from left ), receives o check from Dr. Herbe rt G. Staenner, RML Assistant Director ( left ); while Bryon Hes­tekin, a bacteriolog ist (center), ond Edward Oertli, o machin ist ( second from right), receive the ir owards from Dr. Cornelius B. Philip, Director of the Laboratory. M r. Tallent and Mr. Oertli ore codesigne rs of a port­able opporatus for continuous agitation of serum-antigen mixtures, and Mr. Hestekin is the inventor of a device for restraining groups of mice while their te mperatures ore toke n and recorded over long periods.

"There a re a great number of factors which influence the lives of children - thei,· families, schools, communities, books, 111ov­ies, and television. Much has been said or the influence of tele­vision, good and bad, on the be­havior and lives of childl'en. Since children spend a great deal of time in watching television, it is our hope that we <'an separate fact from fancy in the ,,a,·iety of claims and counterclaims that su1·­round this medium.

"We are sponsoring this project with no preconceh·ed ideas but with a sincere desire to find out ·what we can do about the relationship between television and the behav­ior of children in relation to the various other influences on their behaYior.

"Out of this project, we hope, will come a better understanding of the effects of television upon young people and data indicating how its rich potentials can best be utilized to help fulfill the special needs of children in this complex and changing world."

The steering committee, accord­ing to Chairman Russell, will se­lect the projects to be undertaken, attempt to arrange necessary ti­na11cial support, and establish the appropriate mechanism for super­vising the research work.

"We recognize, of course, that the responsibility for determining the content of programming lies with the broadcasters, and it is not our intention to interfere with that responsibility," he said.

"On the contrary, we ex))ect the results of this work to be an aid, an additional l"esourcc, to the b,-oadcasting industry."

A m ejja 1e Jrom

Socia/ S ecuril'f This i's the thil"d in a .~eries of

a1-tides 1n·epared by the Silva Sp1'i1tU, Md., office of the Sociai Sec11rit11 Adminisl/'a tion for publi­cation in Govern111e11I and i11dtis­ti·ial ne-wRpapers.

George is 6 feel 2 inches tall. He probably weighed o,·er 200 pounds before he got sick. He played football and "·a3 a top bowler.

But George won't e\'el" bowl again. He has multiple sclerosis. George won't ever work again, eithcl'. Two and half years ago, he had to quit his job at the steel company-a good job-that was helµ ing him pay for a new home for his wife and tll'o children.

George lost his home because he could no longer meet t he pay­ments. Two months ago, his bank account showed $322-all he had left in the world.

Out of desperation, George's wife Grace visited the county welfare department. Once there, the cascwo1·ker asked, "What's the amount of your Social Security check?" Grace looked blank. lier family received no Social Security check.

"Let me explain," offered Grace. "My husband is still alh·e, and he's only 40. We can't collect Social Security."

Patiently the caseworker ex­plained that Social Security pay­ments are not confined to old-age and survh·or's payments. "You

THE NIH RECORD

Instrument Symposium And Equipment Exhibit Scheduled Oct. 8-12 The 12th Annual lnstrument

Symposium and Research Equip­ment Exhibit sponsored by NIH will be held here October 8-12.

Dr. James A. Shannon, Dit·ector of ::\TIH, will welcome the sympos­ium participants at the opening session, Monday, October 8, at 8 p.m., in the Clinical Center audi­torium.

Presiding office,· at the first ses­sion will be Dr. A Ian J. Sheppard of the Division of Nutrition, PHS Food and Drug Administration. The subject of the meeting will be thin film and gas chromatography.

Duri11g the 5-day scientific meet­ing-with two sessions dai ly, at 2 p.m. and 8 p.m.-noted im·estiga­tors will report on recent trends a n d developments in research methods and instrumentation.

Discussion topics will cover new ion exch ange techniques through nuclear magnetic responses, optical masers, vacuum u ltraviolet, x-ray microscopy, automation in chemi­cal and biological research, physio­logical monitoring, and x-ray di/'­fraction studies of protein.

Representatives Speak

Speakers on the scientific pro­g1·am will include representatives of universities, medical institu­t ions, industrial firms, and Federal agenciei; engaged in reseai·ch in the I ife sciences.

The research equipment exhjbit, displaying the latest developments of 68 of thf' :Nation's leading sci­entific apparatus manufacturers, will be held concunenlly with the symposium in Buildin,:,; 22. g x­hibit hout·s will be from 11 a.111. to 5 p.m., Octobct· 9 through 12, wit h t he exception of Wt>dnC'~day, Octo­ber 1 0, whc>11 it will remain open until 9 p.111.

Last vear more than 7,000 visi­tors attended the combined lnst1·u­me11l Symposium and Hcsearch Equipment Exhibit. Visitors, in­cluding 24 from foreign countries, came from colleges and univers i­ties, hospitals, rt>search institu­tions, and public and prfr.ite or­ganizations a<'tiYe in publ ic health and medicine.

The exhibit and 8ymposiu111 are open to all professional and tech­nical wo1·kers inteTested in re­search instrumentation.

and George and the children will probably qualify for disability benefits, if you apply," she said.

We now pay George and his family $254 a month. But he has done himself out of more than $3,000 - enough to have salvaged his home.