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    PENGELOLAAN NYERI

    JOKO MURDIYANTO

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    NYERI PERSALINANDIPANDANG DARISUDUT ANESTESI

    JOKO MURDIYANTO

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    DEFINISIPain is Unpleasant sensory

    and emotional experienceassociated with actual or

    potential tissue damage, ordescribe in terms of suchdamage (IASP

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    Pain Experience

    Pain is a personal, su!ec"i#e experience "$a" co%prises &Sensor'()iscri%ina"i#e, *o"i#a"ional(a+ec"i#ean) o-ni"i#e(

    e#alua"i#e)i%ensionsRonald Melzack, Textbook of Pain 4thedition

    S

    omatization

    ?????

    Depression

    Expec

    tation&

    Desir

    e

    Anxie

    ty

    Catastrophization

    Mental

    Phy

    sical

    Spiritual

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    .$a" is Pain/ An unpleasant sensory & emotional experience associated it!

    actual or potential tissue dama"e# or descri$ed in terms o% suc!dama"e '

    T!e International Association %or t!e (tudy o% )ain

    (u$*ecti+e sensation )ain )erceptions ' $ased on expectations# past experience# anxiety#

    su""estions A,ecti+e ' one-s emotional %actors t!at can a,ect pain experience 0e!a+ioral ' !o one expresses or controls pain o"niti+e ' one-s $elie%s .attitudes/ a$out pain

    )!ysiolo"ical response produced $y acti+ation o% speci0c types o%ner+e 0$ers

    1xperienced $ecause o% nociceptors $ein" sensiti+e to extrememec!anical# t!ermal# & c!emical ener"y2

    3omposed o% a +ariety o% discom%orts One o% t!e $ody-s de%ense mec!anism .arns t!e $rain t!at tissues

    may $e in *eopardy/ Acute +s2 3!ronic '

    T!e total person must $e considered2 It may $e orse at ni"!t!en t!e person is alone2 T!ey are more aare o% t!e pain

    $ecause o% no external di+ersions2

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    Pain Acute +s2 3!ronic

    Acute pain is usually related to aneasily identi0ed e+ent or condition2

    3!ronic pain may or may not $erelated to an easily identi0edpat!op!ysiolo"ic p!enomenon#

    may $e multi%actorial# and may $epresent %or an indeterminateperiod o% time2

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    .$ere Does Pain o%e Fro%/

    u"aneous Pain ' s!arp# $ri"!t#$urnin"4 can !a+e a %ast or slo onset

    Deep So%a"ic Pain ' stems %romtendons# muscles# *oints# periosteum#& $2 +essels

    1isceral Pain ' ori"inates %rom

    internal or"ans4 di,used 5 6st& latermay $e locali7ed .i2e2 appendicitis/

    Ps'c$o-enic Pain ' indi+idual %eelspain $ut cause is emotional rat!er t!anp!ysical

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    Pain Sources 8ast +s2 (lo )ain '

    8ast ' locali7ed4 carried t!rou"! A9delta axons in s:in

    (lo ' ac!in"# t!ro$$in"# $urnin"4 carried $y 3 0$ers

    Nocicepti+e neuron transmits pain in%o to spinal cord

    +ia unmyelinated 3 0$ers & myelinated A9delta 0$ers2 T!e smaller 3 0$ers carry impulses 5 rate o% ;2< to

    =2; m>sec2

    T!e lar"er A9delta 0$ers carry impulses 5 rate o% sec2

    Acute +s2 3!ronic

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    .$a" is Re2erre) Pain/

    Occurs aay %rom pain site

    1xamples@ Mcurney-s point# Kerr-s si"n

    Types o% re%erred pain@ Myo%ascial )ain ' tri""er points# small !yperirrita$leareas it!in a m2 in !ic! n2 impulses $om$ard 3N( &are expressed at re%erred pain Acti+e ' !yperirrita$le4 causes o$+ious complaint Batent ' dormant4 produces no pain except loss o% ROM

    (clerotomic & Dermatomic )ain ' deep pain4 mayori"inate %rom sclerotomic# myotomic# or dermatomicn2 irritation>in*ury (clerotome@ area o% $one>%ascia t!at is supplied $y a sin"le

    n2 root

    Myotome@ m2 supplied $y a sin"le n2 root

    Dermatome@ area o% s:in supplied $y a sin"le n2 root

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    Ter%inolo-' !oxious' !arm%ul# in*urious

    Noxious stimuli ' stimulit!at acti+ate nociceptors.pressure# cold>!eatextremes# c!emicals/

    !ociceptor " ner+e receptors

    t!at transmits pain impulses Pain #hreshold' le+el o%

    noxious stimulus reCuired toalert an indi+idual o% apotential t!reat to tissue

    Pain #olerance' amount o%pain a person is illin" or

    a$le to tolerate Accommodationphenomenon' adaptation $yt!e sensory receptors to+arious stimuli o+er anextended period o% time .e2"2super0cial !ot & cold a"ents/2$ess sensiti%e to stimuli&

    'yperesthesia " a$normalacuteness o% sensiti+ity totouc!# pain# or ot!ersensory stimuli

    Paresthesia " a$normal

    sensation# suc! as$urnin"# pric:in"# tin"lin"

    Inhibition " depression orarrest o% a %unction Inhibitor' an a"ent

    t!at restrains>retardsp!ysiolo"ic# c!emical#or en7ymatic action

    Analgesic " a neurolo"ic orp!armacolo"ic state in!ic! pain%ul stimuli areno lon"er pain%ul

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    3ues"ions "o As4 aou" Pain

    )attern@ onset & duration Area@ location Intensity@ le+el

    Nature@ description

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    uestions to As: a$out

    )ainP Q R S T (ECG format)

    )ro+ocation ' Eo t!e in*ury occurred & !atacti+ities t!e painuality 9 c!aracteristics o% pain ' Ac!in"

    .impin"ement/# urnin" .n2 irritation/# (!arp

    .acute in*ury/# Radiatin" it!in dermatome

    .pressure on n2/F

    Re%erral>Radiation 'Re%erred ' site distant to dama"ed tissue t!at

    does not %ollo t!e course o% a perip!eral n2Radiatin" ' %ollos perip!eral n24 di,use(e+erity ' Eo $ad is itF )ain scale

    Timin" ' G!en does it occurF p2m2# a2m2# $e%ore#durin"# a%ter acti+ity# all t!e time

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    uestions to As: a$out

    )ainL O A T E SL5 Loca"ion6

    O 5 O"$er S'%p"o%s6 5 $arac"er& )eep, urnin-, "$roin-7

    A 5 A--ra#a"in- an) Alle#ia"in- 2ac"ors6

    T 5 Ti%in-6E 5 E+ec"& 'our )ail' rou"ine/

    S 5 Se#eri"'6

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    T'pes o2 Ner#es A,erent .Ascendin"/ ' transmit

    impulses %rom t!e perip!ery to t!e$rain

    8irst Order neuron

    (econd Order neuron

    T!ird Order neuron 1,erent .Descendin"/ ' transmit

    impulses %rom t!e $rain to t!eperip!ery

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    Firs" Or)er Neurons

    (timulated $y sensory receptors 1nd in t!e dorsal !orn o% t!e spinal cord Types

    A9alp!a ' non9pain impulses

    A9$eta ' non9pain impulses Bar"e# myelinated Bo t!res!old mec!anoreceptor4 respond to li"!t touc!

    & lo9intensity mec!anical in%o A9delta ' pain impulses due to mec!anical pressure

    Bar"e diameter# t!inly myelinated

    (!ort duration# s!arp# %ast# $ri"!t# locali7ed sensation.pric:lin"# stin"in"# $urnin"/ 3 ' pain impulses due to c!emicals or mec!anical

    (mall diameter# unmyelinated Delayed onset# di,use na""in" sensation .ac!in"#

    t!ro$$in"/

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    Secon) Or)er Neurons

    Recei+e impulses %rom t!e 8ON in t!e dorsal!orn Bamina II# (u$stantia Helatinosa .(H/ 9 determines

    t!e input sent to T cells %rom perip!eral ner+e

    # ells (transmission cells)transmission cell t!atconnects sensory n2 to 3N(4 neurons t!at or"ani7estimulus input & transmit stimulus to t!e $rain

    Tra+el alon" t!e spinot!almic tract )ass t!rou"! Reticular 8ormation

    Types Gide ran"e speci0c

    Recei+e impulses %rom A9$eta# A9delta# & 3

    Nocicepti+e speci0c Recei+e impulses %rom A9delta & 3

    1nds in t!alamus

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    T$ir) Or)er Neurons

    e"ins in t!alamus 1nds in speci0c $rain centers

    .cere$ral cortex/

    )ercei+e location# Cuality# intensity

    Allos to %eel pain# inte"rate pastexperiences & emotions anddetermine reaction to stimulus

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    Descen)in- Neurons

    Descendin" )ain Modulation .Descendin")ain 3ontrol Mec!anism/

    Transmit impulses %rom t!e $rain.corticospinal tract in t!e cortex/ to t!e spinalcord .lamina/ )eriaCuaductal Hray Area .)HA/ ' release

    en:ep!alins Nucleus Rap!e Ma"nus .NRM/ ' release serotonin

    T!e release o% t!ese neurotransmitters in!i$itascendin" neurons

    (timulation o% t!e )HA in t!e mid$rain & NRMin t!e pons & medulla causes anal"esia2

    *ndogenous opioid peptides9 endorp!ins &

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    Neuro"rans%i""ers 3!emical su$stances t!at allo ner+e impulses to mo+e

    %rom one neuron to anot!er 8ound in synapses

    (u$stance ) 9 t!ou"!t to $e responsi$le %or t!etransmission o% pain9producin" impulses

    Acetylc!oline ' responsi$le %or transmittin" motor ner+eimpulses

    1n:ep!alins ' reduces pain perception $y $ondin" to painreceptor sites

    Norepinep!rine ' causes +asoconstriction = types o% c!emical neurotransmitters t!at mediate pain

    1ndorp!ins 9 morp!ine9li:e neuro!ormone4 t!ou"!t to pain t!res!old $y $indin" to receptor sites (erotonin 9 su$stance t!at causes local +asodilation &

    permea$ility o% capillaries ot! are "enerated $y noxious stimuli# !ic! acti+ate

    t!e in!i$ition o% pain transmission 3an $e eit!er excitatory or in!i$itory

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    Sensor' Recep"ors

    *ec$anorecep"ors' touc!# li"!t or deeppressure Meissner-s corpuscles .li"!t touc!/# )acinian

    corpuscles .deep pressure/# Mer:el-s corpuscles

    .deep pressure/ T$er%orecep"ors 9 !eat# cold Krause-s end $ul$s .temp & touc!/# Runi

    corpuscles .in t!e s:in/ ' touc!# tension# !eat4 .in*oint capsules & li"aments ' c!an"e o% position/

    Propriocep"ors ' c!an"e in len"t! ortension Muscle (pindles# Hol"i Tendon Or"ans

    Nocicep"ors' pain%ul stimuli mec!anosensiti+e c!emosensiti+e

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    Ner#e En)in-s A ner+e endin" is t!e termination o% a ner+e 0$er

    in a perip!eral structure2 .)rentice# p2 ?/ Ner+e endin"s may $e sensory .receptor/ or motor

    .e,ector/2

    Ner+e endin"s may $e@Respond to p!asic acti+ity 9 produce an impulse

    !en t!e stimulus is or # $ut not durin"sustained stimulus4 adapt to a constant stimulus.Meissner-s corpuscles & )acinian corpuscles/

    Respond to tonic receptors produce impulses aslon" as t!e stimulus is present2 .muscle spindles#%ree n2 endin"s# Krause-s end $ul$s/

    (uper0cial ' Mer:el-s corpuscles>dis:s# Meissner-scorpuscles

    Deep ' )acinian corpuscles#

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    Ner#e En)in-s

    Mer:el-s corpuscles>dis:s 9

    (ensiti+e to touc! &+i$ration

    (lo adaptin"

    (uper0cial location

    Most sensiti+e Meissner-s corpuscles '

    (ensiti+e to li"!t touc!& +i$rations

    Rapid adaptin"

    (uper0cial location )acinian corpuscles 9

    (ensiti+e to deeppressure & +i$rations

    Rapid adaptin"

    Deep su$cutaneoustissue location

    Krause-s end $ul$s '

    T!ermoreceptor Runi corpuscles>endin"s

    T!ermoreceptor (ensiti+e to touc! &

    tension

    (lo adaptin" 8ree ner+e endin"s 9

    A,erent Detects pain# touc!#

    temperature#mec!anical stimuli

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    Nocicep"ors (ensiti+e to repeated or prolon"ed

    stimulation Mec!anosensiti+e ' excited $y stress &

    tissue dama"e 3!emosensiti+e ' excited $y t!e releaseo% c!emical mediatorsrady:inin# Eistamine# )rosta"landins#

    Arac!adonic Acid )rimary Eyperal"esia ' due to in*ury (econdary Eyperal"esia ' due to

    spreadin" o% c!emical mediators

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    Pain on"rol T$eories

    Hate 3ontrol T!eory 3entral iasin" T!eory

    1ndo"enous Opiates T!eory

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    Ga"e on"rol T$eor' Mel7ac: & Gall# 6L< (u$stantia Helatinosa .(H/ in dorsal !orn o%

    spinal cord acts as a "ate- ' only allos onetype o% impulses to connect it! t!e (ON

    Transmission 3ell .T9cell/ ' distal end o% t!e(ON

    I% A9$eta neurons are stimulated ' (H isacti+ated !ic! closes t!e "ate to A9delta &3 neurons

    I% A9delta & 3 neurons are stimulated ' (H is$loc:ed !ic! closes t!e "ate to A9$etaneurons

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    Ga"e on"rol T$eor' Hate 9 located in t!e dorsal !orn o% t!e spinal cord (maller# sloer n2 carry pain impulses Bar"er# %aster n2 0$ers carry ot!er sensations

    Impulses %rom %aster 0$ers arri+in" 5 "ate 6st

    in!i$itpain impulses .acupuncture>pressure# cold# !eat# c!em2 s:inirritation/2

    rain

    )ain

    Eeat# 3old#Mec!anical

    Hate .Tcells> (H/

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    en"ral 0iasin- T$eor'

    Descendin" neurons are acti+ated$y@ stimulation o% A9delta & 3neurons# co"niti+e processes#

    anxiety# depression# pre+iousexperiences# expectations

    3ause release o% en:ep!alins .)AH/and serotonin .NRM/

    1n:ep!alin interneuron in area o%t!e (H $loc:s A9delta & 3 neurons

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    En)o-enous Opia"es T$eor'

    Beast understood o% all t!e t!eories

    (timulation o% A9delta & 3 0$ers causes

    release o% 9endorp!ins %rom t!e )AH & NRM

    A3TE>9lipotropin is released %rom t!eanterior pituitary in response to pain ' $ro:endon into 9endorp!ins and corticosteroids

    Mec!anism o% action ' similar to en:ep!alinsto $loc: ascendin" ner+e impulses

    1xamples@ T1N( .lo %reC2 & lon" pulseduration

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    Goals in *ana-in- Pain

    Reduce pain 3ontrol acute pain

    )rotect t!e patient %rom %urt!erin*ury !ile encoura"in"pro"ressi+e exercise

    O"$ "

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    O"$er 8a's "o

    con"rol pain 1ncoura"e central $iasin" ' moti+ation#relaxation# positi+e t!in:in"

    Minimi7e tissue dama"e

    Maintain communication > t!e at!lete I% possi$le# allo exercise Medications

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    E%pa" "a$ap 9siolo-i n'eri &

    Proses "rans)u4si

    )roses dimana suaturan"san" nyeri .noxious stimuli/ diu$a! men*adisuatu a:ti0tas listri:# yan" a:an diterima ole!u*un"9u*un" sara%2

    Proses "rans%isi

    (e$a"ai peram$atan ran"san" melalui sara% sensoris menyusul prosestransdu:si2Proses %o)ulasi )roses dimana ter*adiintera:si antara sistem anal"esi: endo"enden"an asupan nyeri yan" masu: :e :ornuposterior2Persepsi Easil a:!ir dari proses yan":omple:s dan uni: yan" men"!asil:an suatu

    perasaan yan" su$ye:ti%2

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    f i

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    fracture/Postoperative

    Onoin or

    impen!in in"ury

    sprain

    #nflamation $

    #nfection

    #nfiltrate! or compresse!

    %tumors&

    stranulate!

    %scar tissue&

    Muscle Stretch

    inflame! %infection &

    Type or Category of Pain

    :6 Ps'c$o-enic

    clear t!atno somatic disorder

    is present

    ;6 Nocicep"i#e3aused $y acti+ity

    in neural pat!aysin response to potentiallytissue9dama"in" stimuli

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    Hoals

    62 De0ne t!e se+erityo%

    pain=2 Assistin t!e selection

    o% appropriateanal"esia

    ?2 1+aluate t!e response

    to treatment)ain Assessment

    *e"$o

    )s

    62 (el% Report

    =2 Team Approac!

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    T!e Met!odolo"yo% )ain Assessment

    The Assessment of the Patient with Pain, Steven Richeimer, M.D. Director USC Pain Management, USC Medica Center, !os Angees, CA, USA, "##$

    Eistory

    )ast Medical Eistory

    3urrent Medications

    )!ysical 1xamination

    (pecial Test

    )syc!olo"ical1+aluation

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    62 BI(T1N

    =2 BO3AT1

    ?2 BOOK

    A(I3

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    'ocation% Patient or nurse mar(s !ra)in

    #ntensity% Patient rates the pain* Scale +se!,

    -uality% +se patint.s )or!s/ e** pric(/ ache/ 0urn/ sharp/ hot etc.

    Onset/ !uration/ variations/ rhythms %spontaneus or evo(e!&,

    Manner of expressin pain,

    1hat relieves the pain?

    &Pain 'ehavio(r)

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    1hatcauses orincreases the pain?

    Effect of pain% %2ote !ecrease! function/ !ecrease! 3uality of life&

    Other comments,

    Plan,

    Accompanying symptoms &eg na(sea)

    Seep

    Appetite

    Physica activity

    Reation with others &eg irrita*iity)

    +motion &eg anger, s(icida, crying)

    Consentration

    ther

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    )ain Assessment (cales

    Uni-Dimensiona Scae M(ti-Dimensiona Scae

    Onlymeas(res pain intensity Appropriate for acute pain

    The most common scae (sed inoutcomeassessment &Anagesic

    efficacy)

    ot! in"ensi"' >se#eri"'?andunpleasan"ness >a+ec"i#e?

    Appropriate %or c$ronic pain Researc$ @pa"$op$'siolo-' S$oul) e use) in clinical

    ou"co%e assess%en"

    4er0al 5atin Scale %45S&

    2one/ mil!/ mo!erate/ severe

    2umeric 5atin Scale %25S&

    4isual Analo Scale %4AS&

    Pictorial Scale

    Mc6ill Pain -uestionnaire %MP-&

    7he 8rief Pain #nventory %8P#&

    7he Memorial Pain Assessment Car!

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    Photoraphic$2umeric Pain Scale

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    Photoraphic$2umeric Pain Scale

    M !ifi !

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    Mo!ifie!

    Mc6ill Pain

    -uestionnaire

    6#P ai:=Q#LP Bumayandan sedan"

    .Meliala# 6/

    6< Minutes

    Sensori4A2e4"i2

    E#alua"i2*aca%6=!r

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    Opioids Anal"esic

    62Morp!ine i+ dose ;26 m">:" it!additional doses o% ;2;< m">:"2

    =2Meperidine i+ dose 6 m">:" it!additional doses ;2< m">:"2

    ?28entanyl i+ dose = ' ? mc">:" it!additional doses titrated $y ;2< mc">:"

    until desired le+el o% anal"esia is reac!ed2

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    Pae)ia"rics

    Morp!ine .i2d2 ;2;< ';26 m">:" i+# t!entitrate# maximum 6; m">dose2

    or

    8entanyl .i2d 69= ">:"# t!en titrate#maximum 6;; ">dose/

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    TERI*A ASIBPERBATIANNYA.ASSALA*UALAIU*