october 23 – 24, 2015omni shoreham hotel

washington, dc

menachem miodovnik, mdeunice kennedy shriver national institute of child health and human developmentnational institutes of healthbethesda, md

e. albert reece, md, phd, mbauniversity of maryland school of medicinebaltimore, md

oded langer, md, phdknoxville, tn

As the maternal age is increasing and the American population is becoming more obese, the number of pregnancies complicated by diabetes and obesity also is increasing. The 14th Biennial Meeting of the Diabetes in Pregnancy Study Group of North America (DPSG-NA) serves as a vehicle for the dissemination of data, gathered through collaboration among basic, translational and clinical researchers and research centers, both nationally and internationally. The meeting will provide attendees with state-of-the-art information on the management of the pregnant patient with diabetes, as well as a forum to discuss novel research ideas and debate current controversies.

The 14th Biennial Meeting of the Diabetes in Pregnancy Study Group of North America will be a two-day symposium featuring didactic lectures, debates and interactive panel discussions, with audience-driven participation and question/answer sessions. The meeting will include a poster session of basic, preclinical and clinical biomedical research in topic areas selected by a DPSG-NA review committee. Internationally and nationally recognized experts will underscore the state-of-the-art relevant information in areas including obesity, metabolic syndrome, hypertension and diabetes. Specific topics that will be presented during the meeting will focus on new insights into the science of diabetes; glucose management; diabetes prevention; genetic underpinnings of diabetes and obesity; preconception care, nutrition, exercise, weight gain and obesity; pharmacokinetic considerations; diagnosis and consequences of diabetic fetopathy.

learning objectives

• Consult appropriate subspecialists to create an integrated team that will deliver optimal care for the diabetic pregnant patient

• Evaluate the pros and cons of pharmacologic options and glucose monitoring strategies. Furthermore, recognize the pharmacokinetic, pharmacodynamic type, dose and frequency for the treatment of diabetes in pregnancy and apply the information to individualize patient care

• Identify patients at highest risk for diabetic fetopathy by recognizing the mechanisms that lead to the abnormal fetal development and perform appropriate studies to make the diagnosis

• Identify patients at higher risk for adverse pregnancy outcomes due to obesity complications and adjust care during the preconception period and gestation

• Recognize the contributions of the placenta to long term health and disease to develop new technologies for real-time assessment of placental health across pregnancy

• Identify other uses of genomic testing to promote pregnancy outcomes, including, but not limited to, markers of placental health, patient response to pharmacological agents and susceptibility to diseases later in life

target audience

This conference is intended for obstetricians, gynecologists, geneticists, endocrinologists, nurses, midwives, residents, fellows, family practitioners, internists, students and healthcare professionals with a special interest in the treatment of the diabetic pregnant patient.

cme accreditation

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of MedStar Washington Hospital Center and the Diabetes in Pregnancy Study Group of North America. MedStar Washington Hospital Center is accredited by the ACCME to provide continuing medical education for physicians.

credit designation

MedStar Washington Hospital Center designates this live activity for a maximum of 14 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

course directors

Menachem Miodovnik, MD Eunice Kenedy Shriver National Institute of Child Health and Human Development National Institutes of Health Bethesda, MD

E. Albert Reece, MD, PhD, MBA University of Maryland School of Medicine Baltimore, MD

Oded Langer, MD, PhDKnoxville, TN

faculty

Raul Artal, MD St. Louis University St. Louis, MO

Robert W. Bendon, MD University of Louisville Louisville, KY

Aaron B. Caughey, MD, PhD Oregon Health Science University Portland, OR

Frank A. Chervenak, MD Weill Medical College of Cornell University New York Presbyterian Hospital New York, NY

Shelley R. Ehrlich, MD, ScD, MPH Cincinnati Children’s Hospital Medical Center Cincinnati, OH

Jacob (Jed) E. Friedman, PhD University of Colorado School of Medicine Anschutz Medical Center Aurora, CO

Maisa N. Feghali, MDMagee-Womens Hospital of University of Pittsburgh Medical CenterPittsburgh, PA

Robert L. Goldenberg, MD Columbia University Medical Center New York, NY

William A. Grobman, MD Northwestern University Feinberg School of Medicine Chicago, IL

Kimberly M. Herrera, MD Mount Sinai Roosevelt Hospital Mount Sinai Health System New York, NY

Carol J. Homko, PhD Temple University Philadelphia, PA

Sandra Hummel, PhD Institute of Diabetes ResearchHelmholtz Zentrum Munchen Munich, Germany

John V. Ilekis, PhD Eunice Kenedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesda, MD

John M. Jakicic, PhD Department of Health and Physical Activity University of Pittsburgh Pittsburgh, PA

Jane C. Khoury, PhD Cincinnati Children’s Hospital Medical Center Cincinnati, OH

Siri L. Kjos, MD, MSEd Harbor-UCLA Medical Center Torrance, CA

Joseph R. Lakowicz, PhD University of Maryland School of Medicine Baltimore, MD

Mark B. Landon, MD The Ohio State University Medical Center Columbus, OH

Justin P. Lavin, Jr., MD Akron General Medical CenterAkron, OH

Elisabeth R. Mathiesen, MDCentre for Pregnant Women with Diabetes, Rigshospitalet University of CopenhagenCopenhagen, DENMARK

Dev Maulik, MD, PhDSchool of Medicine/Truman Medical CenterUniversity of Missouri-Kansas CityChildren’s Mercy Hospital Kansas City, MO

Michael J. Paidas, MD Yale University School of Medicine New Haven, CT

Alan Peaceman, MDNorthwestern UniversityFeinberg School of MedicineChicago, IL

Suzanne Phelan, PhD California Polytechnic State University San Luis Obispo, CA

Xavier Pi-Sunyer, MD, MPH New York Obesity/ Nutrition Research Center Columbia University New York, NY

Toni I. Pollin, PhD University of Maryland School of Medicine Baltimore, MD

Tonse N. K. Raju, MD Eunice Kenedy Shriver National Institute of Child Health and Human Development National Institutes of Health Bethesda, MD

Robert E. Ratner, MD American Diabetes Association Alexandria, VA

Uma M. Reddy, MD, MPH Eunice Kenedy Shriver National Institute of Child Health and Human Development National Institutes of Health Bethesda, MD

Griffin P. Rodgers, MD National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health Bethesda, MD

Barak M. Rosenn, MD Mount Sinai Roosevelt Hospital, Mount Sinai Health System New York, NY

Michael G. Ross, MD, MPH Geffen School of Medicine Fielding School of Public HealthUniversity of California Los Angeles, CA

Siegfried Rotmensch, MD Cedars-Sinai Medical Center Los Angeles, CA

Carolyn M. Salafia, MD Institute for Basic Research Staten Island, NY

Arnon Samueloff, MD Shaare Zedek Medical Center The Hebrew University of Jerusalem Jerusalem, ISRAEL

Christina M. Scifres, MD University of Oklahoma College of Medicine Oklahoma City, OK

Dinesh M. Shah, MDUniversity of Wisconsin Medical SchoolMadison, WI

Nawar M. Shara, MS, PhD Georgetown – Howard University Clinical and Translation Science Center MedStar Health Research Institute Hyattsville, MD

Catherine Y. Spong, MDEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of HealthBethesda, MD

Rhonda D. Szczesniak, PhD Cincinnati Children’s Hospital Cincinnati, OH

Elizabeth A. Thom, PhD George Washington University Biostatistics Center Washington, DC

Ronald J. Wapner, MD Columbia University Medical Center New York, NY

Erika F. Werner, MD Alpert Medical School of Brown University Providence, RI

Arnon Wiznitzer, MD Helen Schneider Hospital for Women Rabin Medical Center Tel Aviv, ISRAEL

Lynn M. Yee, MD, MPH Northwestern University Feinberg School of Medicine Chicago, IL

Yariv Yogev, MD Helen Schneider Hospital for Women Rabin Medical Center Sackler Faculty of Medicine Tel Aviv, ISRAEL

7:30 AM Registration

7:55 AM Welcome and Introduction Robert E. Ratner, MD & E. Albert Reece, MD, PhD, MBA

8:05 AM Diabetes and Obesity: The Seemingly Unending Continuum Griffin P. Rodgers, MD

opening session: setting the stageModerators: Siri L. Kjos, MD, MSEd; Tonse N.K. Raju, MD

8:20 AM Diabetes in Pregnancy in Developing Countries Robert L. Goldenberg, MD

8:45 AM Unraveling the Syndrome of Diabetic Embryopathy: From Cell Signaling to Clinical Care E. Albert Reece, MD, PhD, MBA

9:10 AM Diabetes and Stillbirth Uma M. Reddy, MD, MPH

9:35 AM Should We Deliver an Obese and Diabetic Patient Before 39 Weeks? Aaron B. Caughey, MD, PhD

10:00 AM Roundtable Discussion Moderators: Siri L. Kjos, MD, MSEd; Tonse N. K. Raju, MD Panelists: A. Caughey, R. Goldenberg, U. Reddy, E. A. Reece

10:25 AM Break and Visit the Posters and Exhibits

session i: the genome and perinatal medicine – a never ending storyModerators: John V. Ilekis, PhD; Arnon Samueloff, MD

10:40 AM Maternal Obesity and Fetal Programming Michael G. Ross, MD, MPH

11:05 AM Changing Paradigms: From Prenatal Genetic Diagnosis to Fetal Individualized Medicine Ronald J. Wapner, MD

11:30 AM Gestational Diabetes and Pathways for Programming in Mouse, Monkey and Man: Where Do We Go Next? Jacob E. (Jed) Friedman, PhD

11:55 AM How Poor Communication Can Foil Optimal Care of the Woman with Diabetes Mellitus William A. Grobman, MD

12:20 PM Roundtable Discussion Moderators: John V. Ilekis, PhD; Arnon Samueloff, MD Panelists: J. Friedman, W. Grobman, M. Ross, R. Wapner

12:45 PM Lunch and Visit the Posters and Exhibits

session ii: obesity impact on the clinician – a heavy challenge (part 1)Moderators: Carol J. Homko, PhD; Barak M. Rosenn, MD

1:30 PM Obesity Complicating Pregnancy: The Scope of the Problem Xavier Pi-Sunyer, MD, MPH

1:55 PM Obesity or Diabetes: Which is More Hazardous to the Mother and the Newborn? Oded Langer, MD, PhD

2:20 PM Managing Gestational Weight Gain for the Obese Patient: A Mystery But Far From a Myth Alan Peaceman, MD

2:45 PM Obesity or Diabetes: Impact on Childhood Obesity? Mark B. Landon, MD

3:10 PM Roundtable Discussion Moderators: Carol J. Homko, PhD; Barak M. Rosenn, MD Panelists: M. Landon, O. Langer, A. Peaceman, X. Pi-Sunyer

3:30 PM Break and Visit the Posters and Exhibits

session iii: obesity impact on the clinician – a heavy challenge (part 2)Moderators: Maisa N. Feghali, MD; Nawar M. Shara, PhD

3:45 PM Ethical Challenges of Fetal Genome Sequencing Frank A. Chervenak, MD

4:10 PM Weight Gain and Weight Loss in Normal or Diabetic Pregnancy Yariv Yogev, MD

4:35 PM The Role of Exercise in Reducing the Risks of Obesity/GDM Raul Artal, MD

5:00 PM Roundtable Discussion Moderators: Maisa N. Feghali, MD; Nawar M. Shara, PhD Panelists: R. Artal, F. Chervenak, Y. Yogev

5:20 PM Adjourn

7:30 AM Registration

session iv: the placentaModerators: Robert W. Bendon, MD; Justin P. Lavin, Jr., MD

8:00 AM Update on the Human Placenta Project Catherine Y. Spong, MD

8:25 AM Maternal Health Consequences Following Placenta- Mediated Complications Michael J. Paidas, MD

8:50 AM The Great Obstetrical Syndromes: First Trimester Detection of Placental Disease – External Validity of Algorithms Carolyn M. Salafia, MD

9:15 AM Roundtable Discussion Moderators: Robert W. Bendon, MD ; Justin P. Lavin, Jr., MD Panelists: M. Paidas, C. Salafia, C. Spong

9:30 AM Break and Visit the Posters and Exhibits

session v: diabetes intervention: an end to procrastination and a time for actionModerators: Jane C. Khoury, PhD; Dev Maulik, MD, PhD

9:45 AM The Use of Insulin During Pregnancy: Past, Present and Future Elisabeth R. Mathiesen, MD

10:10 AM Oral Hypoglycemic Agents in Pregnancy: Do the Ends Justify the Means? Oded Langer, MD, PhD

10:35 AM Myo-Inositol: New/Old Agent in Gestational Diabetes Mellitus Erika F. Werner, MD

11:00 AM Impact of the Intrauterine Environment on Long Term Outcomes in the Offspring Robert Ratner, MD

11:15 AM Roundtable Discussion Moderators: Jane C. Khoury, PhD; Dev Maulik, MD, PhD Panelists: O. Langer, E. Mathiesen, R. Ratner, E. Werner

12:00 PM Lunch and Visit the Posters and Exhibits

session vi: women at risk for type 2 diabetes: destined for disease?Moderators: Siegfried Rotmensch, MD; Elizabeth A. Thom, PhD

1:00 PM The Genetic Architecture of Diabetes in Pregnancy Toni I. Pollin, PhD

1:25 PM Assessment of Type 2 Diabetes Mellitus Risk Sandra Hummel, PhD

1:50 PM Applying Innovative Technologies and Interventions for Physical Activity for Diabetes John M. Jakicic, PhD

2:15 PM Lifestyle Interventions After Gestational Diabetes to Avoid Long Term Complications Suzanne Phelan, PhD

2:40 PM Roundtable Discussion Moderators: Siegfried Rotmensch, MD; Elizabeth A. Thom, PhD Panelists: S. Hummel, J. Jakicic, S. Phelan, T. Pollin

session vii: 5 minutes – 5 slides Each presentation will be followed by 5 minutes of Question & AnswerModerators: Christina M. Scifres, MD; Arnon Wiznitzer, MD

3:05 PM Thinking Smaller and Smarter About Glucose Monitoring: The GlucoLens Joseph R. Lakowicz, PhD

3:15 PM Temporal Gestational Modeling of the Impact of Insulin Fluctuation on Perinatal Outcome Rhonda D. Szczesniak, PhD

3:25 PM A Randomized Controlled Trial of Insulin Determir versus Insulin NPH for the Treatment of Pregnant Women with Gestational Diabetes and Type 2 Diabetes Kimberly M. Herrera, MD

3:35 PM Environmental Endocrine Disruptors and Gestational Diabetes: Should We be Concerned? Shelley R. Ehrlich, MD, ScD, MPH

3:45 PM The Intrauterine Experience: Does it Last a Lifetime? Jane C. Khoury, PhD

3:55 PM Health Literacy and Patient Education Issues for Pregnant Patients with Diabetes Lynn M. Yee, MD

4:05 PM Physiologic Interpretation of Proteinuria in Context of Diagnosis of PRE Dinesh M. Shah, MD

4:15 PM Closing Remarks Jacob (Jed) Friedman, PhD; Mencham Miodovnik, MD

The Diabetes in Pregnancy Study Group of North America Scientific Committee invites you to submit abstracts of original investigations for consideration at the 14th Biennial Meeting of the Diabetes in Pregnancy Study Group of North America. Abstracts should constitute recent original research (clinical studies, basic investigation and animal studies are equally encouraged) in the field of diabetes in pregnancy. The content may include portions of prior abstracts and/or manuscripts submitted or presented elsewhere.

abstract categories

• Risk factors for the development of gestational diabetes• Pharmacologic therapy• Nutrition, exercise and weight gain• Bench research• Prevention of diabetes in pregnancy• Translational research in diabetes• Fetal/neonatal complications• Maternal complications

recognition

Selected abstract posters will be displayed at the meeting on October 23-24, 2015

submission details

Abstracts must be submitted electronically at CME.MedStarWashington.org/DPSG by July 3, 2015.

All abstract submitters will be notified of acceptance status no later than August 21, 2015.

If you have any questions, please call 202-877-7947 or send an email to WHCCME@gmail.com.

registration information

Physician................................................................................ $200Resident/Fellow.................................................................... $150Nurse...................................................................................... $150Allied Health/Advanced Practice Clinician....................... $150

online registration preferred

Please visit our secure website at http://CME.MedStarWashington.org/DPSG for updated program and registration information. We are unable to accept registrations or cancellations by telephone. If you wish to pay your registration fee by check, please download and print a registration form and mail it to the address on the registration form with your check.

All registrations will be confirmed by email only. Please use an email address that you check regularly. If you have questions regarding registration or do not receive an email confirmation of your registration within 1-2 business days, please contact us at WHCCME@gmail.com or 202-877-8220.

cancellation policy

Cancellations made in writing by September 8, 2015 will be subject to a 50% penalty. No refunds will be given after September 8, 2015. Cancellations will not be accepted by telephone. In the unlikely event that the course is canceled, we will refund the registration fee, but are not responsible for any travel costs.

Please call 202-877-8220 or email WHCCME@gmail.com if you any questions or need any additional information.

venue information

Omni Shoreham Hotel 2500 Calvert Street, NW, Washington, DC 20008202-234-0700

room block

Please call Omni Reservations at 1-800-THE-OMNI (1-800-849-6664). When making reservations by phone please indicate that you are part of the “Diabetes in Pregnancy Study Group”.

Our preferred discount room block is available Thursday, October 22, 2015 through Saturday, October 24, 2015. Single or double-occupancy rooms are $254 per night plus 14.5% tax.

The cut-off date for making reservations is Monday, September 28, 2015.

NON-PROFIT ORG.U.S. POSTAGE

PAIDMEDSTAR

WASHINGTONHOSPITALCENTER

MedStar Washington Hospital Center110 Irving Street, NW, Suite 6B-5Washington, DC 20010

october 23 – 24, 2015omni shoreham hotel, washington, dc

for the most up-to-date program information& to register to attend, please visit:

cme.medstarwashington.org/dpsg