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    Origins and validity of the

    Osteoarthritis Hip and Knee

    Questionnaire

    Professor Richard Osborne BSc, PhD

    Chair in Public Health

    Public Health Innovation@Deakin,Deakin University

    Melbourne, Australia

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    RMH OWL follow up study:

    Quality of life of people waiting for JRS

    -0.20 0.00 0.20 0.40 0.60 0.80 1.00

    AQoL baseline

    0

    5

    10

    15

    20

    25

    Frequency

    Mean = 0.3885

    Std. Dev. = 0.234

    N = 307

    Populationnorm

    Ackerman IN,

    Graves SE, Wicks

    IP, Bennell KL,

    Osborne RH.

    Severely

    compromised

    quality of life inwomen and those

    of lower

    socioeconomic

    status waiting for

    joint replacement

    surgery.Arthritis

    Rheum

    2005;53(5):653-8.

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    An evidence-based prioritisationand management system is

    required

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    RHM OWL Prioritisation Proposal23 12 2003 Final.doc

    2. Project OutlineThe aim of the project is to develop a system thatfacilitates the appropriate management of people whomay require JRS. This system will involve clinicalpathways to triage people with hip or knee

    osteoarthritis, facilitate fast and slow tracking (ieprioritisation), and ultimately ensure a higherproportion of the most needy people receive timelyJoint Replacement Surgery.

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    Sponsor: Victorian

    Government, Department

    of Human Services

    Field Champions

    Mr Richard de Steiger (RMH)Mr Stan OLoughlin (DH)

    Mr Ian Critchley (GVH)

    Mr Chris Haw (WH)

    Mr Rob Pianta (WH)

    Mr Graeme Brown (Geelong)

    Miss Susan Liew (Austin)Mr Roger Westh (Austin)

    Investigators

    Prof Richard Osborne

    Prof Stephen Graves

    Prof Ian Wicks

    A/Prof Caroline Brand

    Consultants

    Prof Peter Fayers

    Prof Paul Dieppe

    Prof Tony Scott

    Project staff

    RMH: Ms Kerry Haynes

    Ms Peta Chubb

    Ms Catherine JonesMs Tanja Farmer

    Ms Debra RobbinsMs Melanie Hawkins

    GVH: Dr Jennifer Critchley

    WH: Dr Anjali Haikerwal

    DH: Ms Rosie Molloy

    Ms Barbara Newell

    Phase I:

    2.5 years (2004-5)

    Development of amanagement andprioritisation system

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    Sponsor: VictorianGovernment,Department of HumanServices

    Pilot Hospitals

    Geelong

    Peninsula

    Royal Melbourne

    St Vincents

    Investigators

    Prof Richard Osborne

    A/Prof Caroline Brand

    ConsultantsMr Richard de Steiger

    Prof Stephen Graves

    Ms Jenni Livingston

    Ms Fiona Landgren

    Project staffMs Melanie Hawkins

    Ms Catherine Jones

    Ms Jo Slee

    Phase II:

    1.5 years (2006-7)

    Development ofstatewideimplementation plan

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    Development of a

    Multi-Attribute Prioritisation Tool (MAPT)

    State-of-the-art surgeon/patient/systemconsultation, psychometrics and clinimetrics

    Concept Mapping workshops Groups facilitated to identify factors that should be

    considered when determining priority for JRS 4 workshops with orthopaedic surgeons

    4 workshops with patients

    With the grounded consultations we aimed to:

    Ensure that the questionnaire was: Clinically relevant, endorsed and owned by clinical groups

    Implementable

    Embedded into clinical practice

    Appropriate across settings

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    Prioritisation domains generated from

    surgeons and patients

    1. Pain1.1. Sleep disturbance1.2. Rest pain1.3. Pain related to movement

    2. Limitations to dailyactivities

    2.1. Impairment of mobility2.2. Ability to self-care2.3. Level of domestic support2.4. Carer roles

    3. Psychosocial health

    impact

    3.1. Psychological effect of

    disability

    3.2. Social effect of disability

    4. Economic impact

    4.1. Interference with ability to

    work

    4.2. Financial provider for

    others

    5. Recent deterioration

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    MAPT development

    Pre-testing draft ~120 questions

    Derived from what patients and surgeons saidin

    workshops

    Consultation with surgeons and other experts

    Development of draft questions across 5 domains

    Cultural and linguistic audit

    Cognitive interviews with patientsField testing

    60 draft items

    Completed by 600+ patients +/- on OWL

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    Questions

    Guttman-like scales

    Discrete health states in each response

    option Verifiable through a clinical interview

    Attribution to the hip or knee

    Not Likert questions

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    WOMAC indexWestern Ontario & McMaster Osteoarthritis Index

    24 itemsThink about the difficulty you had in doing the following daily physical activities due to your

    arthritis during the last 48 hours. By this we mean your ability to move around and look

    after yourself.

    QUESTION:What degree of difficulty do you have?

    None Mild Moderate Severe Extreme

    8. Descending (going down) stairs

    9. Ascending (going up) stairs

    10. Rising from sitting

    11. Standing

    12. Bending to the floor

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    Weighting items

    Some questions (indications for need for joint

    replacement) are more important than others

    Discrete Choice Experiments

    Surgeons asked to apply clinical judgement to

    patient vignettes

    Helps to appropriately weight clinical red flags

    96 Victorian orthopaedic surgeons participated

    Simple score

    0 (no need for surgery)

    100 (highest need for surgery)

    Victoria has

    ~140

    arthroplasty

    surgeons

    Witt J, Scott A, Osborne RH. Designing Choice Experiments with Many Attributes. An Application to

    Setting Priorities for Orthopaedic Waiting Lists. Health Economics 18: 681-96, 2009

    Orthopaedic Waiting List Project

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    Orthopaedic Waiting List ProjectDiscrete Choice Experiments

    Please indicate whether you are a consultant or registrar:Consultant Registrar

    1 (1.1)

    Patient A Patient BI do not look after, or experience nodifficulty looking after, dependents.

    It is moderately difficult looking afterdependents.

    I have pain that stops me going to

    sleep most of the time.

    I have pain that stops me going to

    sleep all of the time.It does not affect, or causes littleaffect to, my enjoyment of life.

    It makes it moderately or verydifficult for me to enjoy my life.

    I do not getenough help withlooking after myself.

    I do not getenough help with lookingafter myself.

    It makes it moderately difficult formy household to manage financially. It does not affect my householdfinances or it makes it slightlydifficult for my household to managefinancially.

    Higher priority: Patient A Patient B1% 99%

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    The need for surgery assessed

    by the MAPT

    MAPT WOMAC

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    Validation

    Administered to 1000+ patients Correlation with international standards

    Oxford Hip / Knee

    WOMAC

    Quality of Life (AQoL)

    SF36 EQ-5D

    Hospital Anxiety and Depression Scale

    Clinical veracity of the questionnaire Face validity

    Construct validity Test re-test reliability

    Practicality response rate (patient, health professional)

    Gaming and stoicism

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    Correlation R=0.80

    Correlation R=0.84

    Correlation between the MAPT and

    other questionnaires

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    Correlation between the MAPT and

    other questionnaires

    MAPT MAPT MAPT

    Whole Sample Hips Only Knees Only

    Oxford Hip - 0.8 -

    Oxford Knee - - 0.75WOMAC

    Pain 0.75 0.87 0.62

    Stiffness 0.66 0.70 0.68

    Physical Function 0.75 0.81 0.88

    WOMAC Total 0.78 0.84 0.92

    MAPT

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    MAPTshowed

    appropriate

    correlationswith other

    scales

    MAPT

    Whole Sample

    AQoL

    Independent Living -0.57

    Social Relationships -0.47

    Physical Senses -0.13Psychological Wellbeing -0.75

    AQoL Total -0.71

    EQ-5D (Euroqol) -0.77

    HADS

    Depression 0.62

    Anxiety 0.58

    SF-36

    Physical Function -0.57

    Role Physical -0.59

    Bodily Pain -0.36

    General Health -0.32Vitality -0.50

    Social Function -0.60

    Role Emotional -0.54

    Mental Health -0.44

    Physical Summary -0.46

    Mental Summary -0.51

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    Reliability

    Internal consistency reliability

    Very High

    Cronbachs alpha coefficient 0.87 (n=854)

    Test-retest reliability

    High

    Participants on the OWL (n=80).

    Two-week interval retest ICC = 0.75

    MDD = about 10 units on the 100 unit scale

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    MAPT scores x time since surgery

    Weeks Since Surgery N Mean SD

    Currently on OWL 460 45.5 30.4

    1 12 54 21.8 27.5

    13 24 32 11.8 22.3

    25 -104 118 6.8 15.4

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    Coordinator vs patient score(ICC = 0.74)

    Coordinator

    marks higher

    than patient

    (stoic?)

    Coordinator

    marks lower

    than patient

    (gaming?)

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    Key points:

    MAPT contains the information a clinician needs for

    making sound clinical (holistic) judgments

    key information on a platter

    Free of bias

    Hip/knee, age, education, gender

    Transparent

    Supports equitable clinical care Developed and validated using state-of-the-art

    techniques to prioritise care

    The MAPT is a core element of bringing order into

    what was a chaotic system

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    Thank you

    [email protected]

    mailto:[email protected]:[email protected]