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ACM NANOCOM 2015, Boston, MA, 21-22 September 2015 WWW.CONAN.DIEI.UNIPG.IT/LAB WWW.FET-CIRCLE.EU @FETCIRCLE [email protected] This project has received EU funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No. 665564 Models of Molecular Communications Systems Dr. Mauro Femminella CNIT - University of Perugia [email protected]

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Page 1: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

ACM NANOCOM 2015, Boston, MA, 21-22 September 2015

WWW.CONAN.DIEI.UNIPG.IT/LABWWW.FET-CIRCLE.EU

@[email protected]

This project has received EU funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No. 665564

Models of Molecular

Communications Systems

Dr. Mauro FemminellaCNIT - University of Perugia

[email protected]

Page 2: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

Summary

Definition & high level view

TX-RX model

Taxonomy of channel models

A case study: pure diffusion

Conclusion and future work

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Page 3: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

MolCom Definition:

Molecular communication is defined as the transmission and reception of information by means of molecules among nanomachines

Introductory material: I. F. Akyildiz et al., “Nanonetworks: A New Communication Paradigm”,

Computer Networks, 2008. T. Nakano et al., “Molecular communication and networking:

Opportunities and challenges”, IEEE Trans. on NanoBioscience, 2012 T. Nakano et al., “ Molecular Communication Among Biological

Nanomachines: A Layered Architecture and Research Issues”, IEEE Trans. on NanoBioscience, 2014

L. Felicetti et al. “Applications of molecular communications to medicine: A survey”, Nano Communication Networks, 2016

N. Farsad et al. “A Comprehensive Survey of Recent Advancements in Molecular Communication”, IEEE Comm. Surveys & Tutorials, in press

Page 4: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Technology for nanomachines

Page 5: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

MolCom: a big picture

Page 6: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Taxonomy of active research areas

Page 7: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

TX-RX model

Traditional

MolCom

Page 8: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

A protocol stack model

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Page 9: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Taxonomy on propagation schemes

Page 10: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Active vs. Passive transport

Page 11: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Free diffusion: reference model

r0

rr

Page 12: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Free diffusion

Fick’s law of diffusion

Concentration in free space w/o receiver for a pulse of Q molecules

Dt

rr

eDtQrtrp4

)(

30

20

4)|,(

c

b

r

TKD

6

Page 13: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Free diffusion with receiver

Boundary conditions:

Very far from transmitter

On the receiver surface

Page 14: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Absorbing receiver

H. B. Yilmaz et al., "3-D Channel Characteristics for Molecular Communications with an Absorbing Receiver“, IEEE Communications Letters, 2014.

Page 15: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Receiver with absorbing receptors

A. Akkaya et al., "Effect of Receptor Density and Size on Signal Reception in Molecular Communication via Diffusion With an Absorbing Receiver“, IEEE Communications Letters, 2015.

Page 16: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

A more advanced scenario

L. Felicetti et al., "Modeling CD40-Based Molecular Communications in Blood Vessels,“ IEEE Transactions on NanoBioscience, 2014.

Page 17: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Proposed modelNumberbonds

Nu

mb

erV

CA

Ms

......

......

......

...

Page 18: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Parameter matching

Page 19: Models of Molecular Communications Systems - unipg.itconan.diei.unipg.it/pub/Femminella_SSPG.pdf · Fick’s law of diffusion ... Environmental monitoring ... management and deployment

2nd IEEE Italy Section PhD Summer SchoolPerugia, June 6-10 2016

Molecular communications focus on

Modeling of communication aspects At all networking layers

Potential disruptive applications Medicine

Food control

Environmental monitoring

Validation by experiment is the next step

Examples: bacteria, flux chambers, microfluidics

Drop me an email at [email protected] if you are interested in MolCom!

Conclusion & outlook