7
Metacognitive beliefs in unipolar and bipolar depression: A comparative study GÖKHAN SARISOY, OZAN PAZVANTO ĞLU, DENIZ DENIZ ÖZTURAN, NAILE DILA AY, TUBA YILMAN, SEMA MOR, I Ş IL ZABUN KORKMAZ, ÖMER FARUK KAÇAR, KÜBRA GÜMÜ Ş Sarısoy G, Pazvanto ğlu O, Özturan DD, Ay ND, Yılman T, Mor S, Korkmaz IZ, Kaçar ÖF, Gümü ş K. Metacognitive beliefs in unipolar and bipolar depression: A comparative study. Nord J Psychiatry 2013;Early Online:1–7. Aims: The purpose of this study was to perform a comparative investigation of metacognitive beliefs regarding pathological worry in patients with unipolar and bipolar depressive disorder. Methods: Those subjects with acute depressive episodes among patients diagnosed with major depressive disorder (unipolar) or bipolar disorder on the basis of DSM-IV diagnostic criteria (unipolar n 51, bipolar n 45), and healthy controls ( n 60), were included in the study. Participants were administered the Meta-Cognitions Questionnaire (MCQ-30) in order to determine metacognitive beliefs. The relationship between metacognitive beliefs and anxiety severity, depression severity and self-esteem in the unipolar and bipolar patients groups was then examined. Results: Scores for negative beliefs about worry concerning uncontrollability and danger and for beliefs about the need to control thoughts were higher in both the unipolar and bipolar depression groups than in the healthy controls ( P 0.05). Lack of cognitive confidence scores were higher in the bipolar group than in the healthy controls ( P 0.05). Metacognitive beliefs (to a greater extent in parameters in the bipolar group) were correlated with anxiety level, depression level and self-esteem in both patient groups. Conclusion: In addition to metacognitive beliefs known to be associated with ruminations in unipolar and bipolar depression, metacognitive beliefs can also be seen in association with worry. Worry-associated metacognitive beliefs should be the subject of focus in the identification of metacognitive beliefs in depression patients and in metacognitive therapy in these patients. • Bipolar, Depression, Metacognition, Unipolar, Worry. Gökhan Sarısoy, M.D., Assistant Professor, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Tıp Fakültesi Psikiyatri A.D. Samsun 55139, Turkey, E-mail: [email protected]; Accepted 9 June 2013. M etacognitions are beliefs concerning the power, meaning and significance of thoughts, and the need to control these thoughts (1). They are a psychological process associated with the interpretation, control and modification of repetitive negative thinking such as worry and rumination (2). Nolen-Hoeksama defines rumination as “behaviors and thoughts that passively focus one’s attention to one’s depressive symptoms and on the impli- cations of these symptoms (3). Worry is a chain of thoughts and images, negatively affect-laden and rela- tively uncontrollable; it represents an attempt to engage in mental problem solving on an issue whose outcome is uncertain but contains the possibility of one or more neg- ative outcomes; consequently, worry relates closely to the fear process” (4). According to the Self-Regulatory Executive Function (S-REF) model, in addition to establishing a general predisposition to the formation of psychopathologies, metacognitive beliefs also play an important role in the progression of psychopathologies. This picture is known as Cognitive Attentional Syndrome. This syndrome is characterized by heightened self-focused attention, threat monitoring, recyclical thinking patterns (rumination and worry), activation of dysfunctional beliefs and self- regulation strategies that fail to modify maladaptive self-knowledge (1). According to the S-REF model, metacognitive beliefs lead to the development and per- sistence of psychopathologies by causing maladaptive response styles (thought suppression, cognitive avoidance of feared situations, depressive rumination etc., all of which fail to reduce anxiety or threat) (1, 5). The Meta- Cognitions Questionnaire (MCQ) was developed in order to investigate dysfunctional metacognitive beliefs on the basis of the S-REF model (6, 7). This scale measures © 2013 Informa Healthcare DOI: 10.3109/08039488.2013.814710

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Page 1: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

Metacognitive beliefs in unipolar and bipolar depression: A comparative study G Ö KHAN SARISOY , OZAN PAZVANTO Ğ LU , DENIZ DENIZ Ö ZTURAN , NAILE DILA AY , TUBA YILMAN , SEMA MOR , I Ş IL ZABUN KORKMAZ , Ö MER FARUK KA Ç AR , K Ü BRA G Ü M Ü Ş

Sar ı soy G, Pazvanto ğ lu O, Ö zturan DD, Ay ND, Y ı lman T, Mor S, Korkmaz IZ, Ka ç ar Ö F, G ü m ü ş K. Metacognitive beliefs in unipolar and bipolar depression: A comparative study. Nord J Psychiatry 2013;Early Online:1–7.

Aims: The purpose of this study was to perform a comparative investigation of metacognitive beliefs regarding pathological worry in patients with unipolar and bipolar depressive disorder. Methods: Those subjects with acute depressive episodes among patients diagnosed with major depressive disorder (unipolar) or bipolar disorder on the basis of DSM-IV diagnostic criteria (unipolar n � 51, bipolar n � 45), and healthy controls ( n � 60), were included in the study. Participants were administered the Meta-Cognitions Questionnaire (MCQ-30) in order to determine metacognitive beliefs. The relationship between metacognitive beliefs and anxiety severity, depression severity and self-esteem in the unipolar and bipolar patients groups was then examined. Results: Scores for negative beliefs about worry concerning uncontrollability and danger and for beliefs about the need to control thoughts were higher in both the unipolar and bipolar depression groups than in the healthy controls ( P � 0.05). Lack of cognitive confi dence scores were higher in the bipolar group than in the healthy controls ( P � 0.05). Metacognitive beliefs (to a greater extent in parameters in the bipolar group) were correlated with anxiety level, depression level and self-esteem in both patient groups. Conclusion: In addition to metacognitive beliefs known to be associated with ruminations in unipolar and bipolar depression, metacognitive beliefs can also be seen in association with worry. Worry-associated metacognitive beliefs should be the subject of focus in the identifi cation of metacognitive beliefs in depression patients and in metacognitive therapy in these patients.

• Bipolar, Depression, Metacognition, Unipolar, Worry.

G ö khan Sar ı soy, M.D., Assistant Professor, Psychiatry Department, School of Medicine, Ondokuz Mayis University, T ı p Fak ü ltesi Psikiyatri A.D. Samsun 55139, Turkey, E-mail: [email protected]; Accepted 9 June 2013.

Metacognitions are beliefs concerning the power,

meaning and signifi cance of thoughts, and the need

to control these thoughts (1). They are a psychological

process associated with the interpretation, control and

modifi cation of repetitive negative thinking such as worry

and rumination (2). Nolen-Hoeksama defi nes rumination

as “ behaviors and thoughts that passively focus one ’ s

attention to one ’ s depressive symptoms and on the impli-

cations of these symptoms (3). Worry is a chain of

thoughts and images, negatively affect-laden and rela-

tively uncontrollable; it represents an attempt to engage

in mental problem solving on an issue whose outcome is

uncertain but contains the possibility of one or more neg-

ative outcomes; consequently, worry relates closely to the

fear process ” (4).

According to the Self-Regulatory Executive Function

(S-REF) model, in addition to establishing a general

predisposition to the formation of psychopathologies,

metacognitive beliefs also play an important role in the

progression of psychopathologies. This picture is known

as Cognitive Attentional Syndrome. This syndrome is

characterized by heightened self-focused attention, threat

monitoring, recyclical thinking patterns (rumination and

worry), activation of dysfunctional beliefs and self-

regulation strategies that fail to modify maladaptive

self-knowledge (1). According to the S-REF model,

metacognitive beliefs lead to the development and per-

sistence of psychopathologies by causing maladaptive

response styles (thought suppression, cognitive avoidance

of feared situations, depressive rumination etc., all of

which fail to reduce anxiety or threat) (1, 5). The Meta-

Cognitions Questionnaire (MCQ) was developed in order

to investigate dysfunctional metacognitive beliefs on the

basis of the S-REF model (6, 7). This scale measures

© 2013 Informa Healthcare DOI: 10.3109/08039488.2013.814710

Page 2: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

G. SARISOY ET AL.

2 NORD J PSYCHIATRY·EARLY ONLINE·2013

about ruminations. The rumination-metacognition model

in depression is supported in clinical and non-clinical

samples in several studies (19 – 23).

In addition to ruminations, pathological worry is

another frequently seen clinical characteristic seen in

depressive disorder patients (24, 25). Depression studies

in the literature also focus on the relationship between

metacognitive beliefs and rumination. The number of

studies on the relationship between metacognitive beliefs

and pathological worry in these patients is limited (5,

11). To the best of our knowledge, there have been no

previous comparative studies evaluating metacognitive

beliefs and pathological worry in unipolar and bipolar

depression samples.

Aims The fi rst aim of this study was to perform a comparative

determination of metacognitive beliefs regarding patho-

logical worry in unipolar and bipolar depression patients.

The second aim was to examine the relationship between

metacognitive beliefs and depression, severity of anxiety

and self-esteem in both patient groups.

Method Participants and procedures This study was performed at the Ondokuz May ı s Univer-

sity Faculty of Medicine Department of Psychiatry,

Turkey, between February and August 2012, with a total

of 156 subjects – 51 with unipolar depression, 45 with

bipolar depression and 60 healthy volunteers. Patients

undergoing acute depressive episodes from among sub-

jects diagnosed with major depressive disorder and bipo-

lar disorder on the basis of DSM-IV diagnostic criteria

between these dates were included. Healthy controls were

selected from a social sample, particularly friends and

relatives of the authors, and from hospital personnel.

Exclusion criteria for the unipolar and bipolar depressive

group were illiteracy, mental retardation, brain injury or

trauma, neurological disease, depressive episode being of

a psychotic nature and substance abuse. Exclusion crite-

ria for the control group were a continuing psychiatric

disorder, illiteracy, mental retardation, brain injury or

trauma, neurological disease and substance abuse.

Unipolar depression, bipolar depression and control

group socio-demographic data were investigated using a

semi-structured form, and all three groups were adminis-

tered the MCQ-30. Unipolar and bipolar depression

patients were also administered the Beck Depression,

Beck Anxiety and Rosenberg Self-Esteem scales. The

patient groups and control group were compared in terms

of MCQ subscale scores. The relationship between MCQ

subscale scores in each group and anxiety, depression

and self-esteem was investigated.

metacognitive beliefs associated with worry, frequently

seen in anxiety disorder, especially generalized anxiety

disorder (GAD), and other disorders. The scale consists

of fi ve subsections. Three of these inquire into beliefs

about positive beliefs about worry, negative beliefs and

the control of worries. The other two subsections inquire

into cognitive self-consciousness and lack of confi dence

regarding cognitive functions (6, 7).

Metacognitive beliefs have been studied in anxiety

disorders such as obsessive – compulsive symptoms (8, 9),

obsessive – compulsive disorder (OCD) (10 – 13), panic

disorder (PD) (5, 13, 14), GAD (5, 11, 15), social pho-

bia (SP) (5) and post-traumatic stress disorder (PTSD)

(16), and particularly in disorders such as schizophrenia

(12, 14) and hypochondriasis (17).

Studies in the literature regarding metacognitive

beliefs have focused on anxiety disorders, such as OCD,

GAD and PD. Scores for “ negative beliefs about worry

concerning uncontrollability and danger ” and “ beliefs

about the need to control thoughts ” have been shown to

be higher in OCD (10, 12, 13), PD (13, 14) and GAD

(11, 14) patients than in healthy controls. These studies

have suggested that metacognitive beliefs about worry

are correlated with anxiety disorders. Beliefs about the

need to control thoughts have been found to be corre-

lated with obsessive – compulsive symptoms in OCD

patients and have been set out as a potential therapeutic

target in therapy for the reduction of these symptoms

(12, 18). Another fi nding regarding OCD and GAD is

that patients feel a lack of confi dence in cognitive func-

tions such as memory, attention and concentration (8, 10,

11, 13). Increased cognitive self-consciousness has also

been determined in OCD patients (11).

In contrast to the worry-metacognition model in anxi-

ety disorders, a rumination-metacognition model has been

suggested in depression patients. A metacognitive model

has been established as the result of both clinical studies

involving depressive disorder and in non-clinical samples

(19, 20). According to the clinical model hypothesis,

positive metacognitions initiate ruminations. Positive

metacognitions are beliefs concerning ruminations help-

ing to solve problems (reducing discrepancies between

the negative life style) (e.g. “ In order to understand my

feelings of depression I need to ruminate on my prob-

lems ” ). When positive metacognitions are inadequate in

the resolution of problems, negative metacognitions about

ruminations begin to emerge. Negative metacognitions

are beliefs regarding the uncontrollability of ruminations,

and that they are harmful or have negative interpersonal

and social outcomes (e.g. “ Ruminating means I ’ m out of

control ” or “ People will reject me if I ruminate ” ). Negative

metacognitions about ruminations contribute to the devel-

opment and persistence of depression. Additionally,

decreases in confi dence in cognitive functioning contribute

to the development of positive and negative metacognitions

Page 3: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

METACOGNITIVE BELIEFS IN DEPRESSION

NORD J PSYCHIATRY·EARLY ONLINE·2013 3

between 0 and 3, and consisting of 21 items (29). The

reliability and validity of the Turkish-language version

was evaluated by Ulusoy et al (30).

The Rosenberg Self-Esteem Scale (RSES) : Developed

by Rosenberg in 1965, the scale consists of 63 multiple

choice questions in 12 sub-categories. The fi rst 10 items

are used to measure self-esteem. We evaluated these fi rst

10 items of the scale. High values indicate high self-es-

teem (31): The relevance-reliability for Turkey was

established by Ç uhadaro ğ lu (32).

Statistics Statistical analysis was carried out using SPSS 16.0 for

Windows. The chi-square test was used to compare cate-

goric variables. Student ’ s t -test was used for comparison

of data for two groups obtained by measurement, and

analysis of variance (one-way ANOVA) was used to

compare three groups. As variances for the post hoc test

were equal, Tukey ’ s test was used. Cohen ’ s method was

used to determine effect size in comparison of two

groups. For this index, cutoffs of 0.2, 0.5 and 0.8 are, by

convention, interpreted as small, medium and large effect

sizes, respectively. Effect size index (as partial eta-

squared, η 2 ) for one-way ANOVA is computed using a

general linear model procedure. For this index, cutoffs of

0.01, 0.06 and 0.14 are, by convention, interpreted as

small, medium and large effect sizes, respectively. Cor-

relation analysis was performed between MCQ subscale

scores and depression, anxiety and self-esteem scale

scores in both the bipolar and unipolar groups (Pearson).

Correlation coeffi cients of 0.30 – 0.49 were regarded as

low, 0.50 – 0.69 as moderate, 0.70 – 0.89 as high and 0.90 –

1.00 as very high (33). The data obtained by measure-

ment were expressed as arithmetical mean � standard

deviation, and those obtained by counting as percentages.

P � 0.05 was regarded as signifi cant.

Results Comparison of groups in terms of socio-demographic characteristics There was no difference between the unipolar depression,

bipolar depression and control groups in terms of age,

gender, marital status, income level, place of residence

and total years in education ( P � 0.005) (Table 1).

Various clinical characteristics of the unipolar and bipolar depression patients Mean number of depressive episodes experienced was

3.29 � 3.97 (Min � 1; Max � 20) in the unipolar group

and 4.48 � 5.00 (Min � 0; Max � 18) in the bipolar group

( t � � 1.69, P � 0.09). Mean number of manic (and

mixed) episodes in the bipolar group was 2.33 � 1.55

Ethical considerations The study protocol was approved by the local ethics

committee, and all patients gave written informed consent.

Measures Socio-demographic and clinical data form : This form

inquired into all participants ’ ages, gender, marital status,

income level, place of residence and total years spent in

education, and these were all recorded. Various clinical

data such as patients ’ past episode types and numbers,

age at onset of disease and duration of disease were

obtained from our mood clinic patient records and

recorded on this form.

The MCQ-30 : developed by Wells & Cartwright-Hat-

ton (7). It consists of fi ve conceptually different but

inter-related factors: (1) positive beliefs about worry (e.g.

“ worrying helps me cope ” , “ worrying helps me to avoid

problems in the future ” ); (2) negative beliefs about worry

concerning uncontrollability and danger (e.g. “ when I

start worrying I cannot stop ” , “ my worrying is danger-

ous for me ” ); (3) beliefs about lack of cognitive confi -

dence (e.g. “ my memory can mislead me at times ” , “ I

have little confi dence in my memory for words and

names ” ); (4) beliefs about the need to control thoughts

(e.g. “ not being able to control my thoughts is a sign of

weakness ” , “ I will be punished for not controlling cer-

tain thoughts ” ); and (5) cognitive self-consciousness (e.g.

“ I pay close attention to the way my mind works ” ,

“ I monitor my thoughts ” ). All factors contain two com-

mon compounds, positive and negative metacognitive

beliefs and metacognitive processes (selective attention,

observation of internal cognitive processes). After read-

ing the statement in each item, participants select the

response most appropriate to them by placing a mark on

a Likert-type classifi cation scale from 1 ( “ I defi nitely

disagree ” ) to 4 ( “ I defi nitely agree ” ). Total possible

scores from the scale range from30 to 120, with higher

scores indicating increased pathological-type metacogni-

tive activity (7). The MCQ-30 has good reliability and

validity. Cronbach coeffi cient alphas for the subscales

range from 0.72 to 0.93. Tosun & Irak investigated the

psychometric characteristics of the scale, adapted it in a

Turkish sample and determined its validity and reliabil-

ity. The Turkish-language version of the form was found

to be valid and reliable (26).

The Beck Depression Inventory (BDI) : This scale was

developed by Beck et al (27) and is widely used in

measuring depression symptom levels. The relevance-

reliability of this scale for Turkey was determined by

Hisli (28).

The Beck Anxiety Scale (BAS) : Developed by Beck

et al., this is a self-evaluation scale used for the purpose

of determining the frequency and intensity of individuals ’

anxiety symptoms. It is a Likert-type scale scored

Page 4: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

G. SARISOY ET AL.

4 NORD J PSYCHIATRY·EARLY ONLINE·2013

thoughts ( F � 6.994, P � 0.001, medium effect size � 0.08)

subscale scores. Both subscale scores were higher in the

unipolar and bipolar groups than in the controls. There

was no difference between the unipolar and bipolar

depression groups in terms of these two subscale scores.

However, a difference was determined between the

groups in terms of lack of cognitive confi dence subscale

scores ( F � 4.832, P � 0.009, medium effect size � 0.06).

Lack of cognitive confi dence scores were higher in the

bipolar depression group than in the control group. There

was no difference between the unipolar depression and

control groups. No difference was also determined

between the unipolar and bipolar depression groups. No

difference was also determined between the groups in

terms of positive beliefs about worry and cognitive self-

consciousness subscale scores ( P � 0.05) (Table 2).

Correlation between MCQ subscale scores and depression, anxiety and self-esteem scores in the bipolar and unipolar depression groups In the bipolar depression group, positive beliefs about

worry scores exhibited a low, positive correlation with

anxiety and depression scores. Negative beliefs about

worry concerning uncontrollability and danger scores

(Min � 1; Max � 7) and mean number of hypomanic

episodes was 0.80 � 1.34 (Min � 0; Max � 6).

Age at onset of disease was 33.06 � 12.00 years in

the unipolar group and 28.11 � 9.56 years in the bipolar

group ( t � 2.21, P � 0.03). Duration of disease was

3.26 � 6.02 years in the unipolar group and 11.22 � 10.52

in the bipolar group ( t � � 4.47, P � 0.000).

Mean Beck Depression Scale score was 29.20 � 9.95

in the unipolar group and 30.22 � 9.72 in the bipolar

group ( t � � 0.51, P � 0.61). Mean Beck Anxiety Scale

score was 25.80 � 13.59 in the unipolar group and

28.82 � 14.16 in the bipolar group ( t � � 1.06, P � 0.29).

Mean Rosenberg Self-Esteem Scale score was

15.69 � 5.79 in the unipolar group and 13.13 � 5.17 in

the bipolar group ( t � 2.27, P � 0.03, small effect

size � � 0.59).

Comparison of the unipolar depression, bipolar depression and control groups in terms of MCQ subscale scores The difference was determined between the groups in

terms of negative beliefs about worry concerning uncon-

trollability and danger ( F � 9.772, P � 0.000, medium

effect size � 0.11) and beliefs about the need to control

Table 1. Comparison of groups in terms of socio-demographic characteristics.

Unipolar group Bipolar group Control

( n � 51) % ( n � 45) % ( n � 60) % χ 2 / F P

Age 39.65 � 12.84 39.50 � 12.10 36.63 � 7.54 F � 1.36 0.26

Gender χ 2 � 2.56 0.28

Female 33 35.5 29 31.2 31 33.3

Male 18 28.6 16 25.4 29 46.0

Marital status 15 25.9 25 43.1 χ 2 � 0.88 0.64

Single 18 31.0 30 30.6 35 35.7

Married 33 33.7

Income level χ 2 � 0.24 0.89

Low 10 34.5 9 31.0 10 34.5

Average/high 41 32.3 36 28.3 50 39.4

Residence χ 2 � 3.48 0.17

City 37 29.8 35 28.2 52 41.9

Town/village 14 43.8 10 31.2 8 25.0

Total years spent in education 9.76 � 3.41 9.89 � 4.40 11.00 � 3.89 F � 1.69 0.19

Total 51 100.0 45 100.0 60 100.0

Table 2. Comparison of groups in terms of Meta-Cognitions Questionnaire (MCQ) subscale scores.

Unipolar group (1)

( n � 51)

Bipolar group (2)

( n � 45)

Control group (3)

( n � 60) F P

Effect size

( η 2 )

Post hoc

(Tukey)

Positive beliefs about worry 12.63 � 4.42 13.58 � 4.48 12.22 � 4.26 1.270 n.s.

Negative beliefs about worry concerning

uncontrollability and danger

15.84 � 4.67 17.00 � 3.98 13.43 � 4.07 9.772 0.000 0.11 * 1/3, 2/3

Lack of cognitive confi dence 14.41 � 4.73 15.02 � 4.54 12.40 � 4.52 4.832 0.009 0.06 * 2/3

Beliefs about the need to control thoughts 15.84 � 4.52 16.42 � 4.52 13.53 � 3.81 6.994 0.001 0.08 * 1/3, 2/3

Cognitive self-consciousness 15.06 � 3.73 15.42 � 3.59 16.65 � 4.13 2.617 n.s.

Note: signifi cance P � 0.05, n.s., non-signifi cant, η 2 ; partial eta-squared for ANOVA results.

* Medium effect size.

Page 5: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

METACOGNITIVE BELIEFS IN DEPRESSION

NORD J PSYCHIATRY·EARLY ONLINE·2013 5

The fi rst aim of this study was to perform a compara-

tive determination of metacognitive beliefs associated

with pathological worry in unipolar and bipolar depres-

sion patients, because pathological worry is frequently

seen in addition to ruminations in depression patients

(24, 25). The literature contains many studies regarding

the rumination-metacognition correlation in depression

patients (19 – 23), while the number of those regarding

the worry-metacognition correlation is limited (5, 11). In

the fi rst of these studies, Wells & Carter used the MCQ

and showed that metacognition levels in depression

patients were lower compared with GAD patients, simi-

lar to those of PD patients, and higher than those in SP

patients and healthy controls (5). In another study, Brah-

man determined that metacognition levels were higher in

depression, GAD and OCD patients compared with the

control group (11). Furthermore, positive beliefs about

worry levels in depressive patients were higher than

those in OCD patients (11): The primary objective in

these two studies was not to use MCQ to measure the

worry-metacognition relationship in depressive patients,

but to perform a comparison with anxiety disorders. No

distinction was made between bipolar and unipolar

depression in either of these two studies. “ Negative

beliefs about worry concerning uncontrollability and dan-

ger ” and “ beliefs about the need to control thoughts ”

subscale scores in both our bipolar and unipolar depression

groups were higher than those of the healthy controls. Our

results and those of these two studies in the literature show

that in addition to the known rumination-metacognition

relationship in depression patients, metacognitive beliefs

regarding worry may also be signifi cant. Researchers tend

to correlate worry with anxiety disorders (and particularly

GAD), and rumination with depressive disorder. However,

Hong (34) and Hoyer et al. (35) reported in a non-clinical

sample and Goring & Papageorgieu (25) in a clinical

exhibited a low negative correlation with self-esteem

scores, a low positive correlation with depression scores

and a moderate positive correlation with anxiety scores.

Lack of cognitive confidence and cognitive self-

consciousness scores exhibited a low positive correlation

with anxiety scores. Beliefs about the need to control

thoughts scores were moderately negatively correlated

with self-esteem scores, lowly positively correlated with

depression scores and moderately positively correlated

with anxiety scores (Table 3).

In the unipolar depression group, positive beliefs

about worry and cognitive self-consciousness scores

exhibited no correlation with self-esteem, anxiety or

depression scores. Negative beliefs about worry concern-

ing uncontrollability and danger scores exhibited a low

negative correlation with self-esteem scores and a low

positive correlation with anxiety scores. Lack of cogni-

tive confi dence scores were lowly positively correlated

with anxiety scores. Beliefs about the need to control

thoughts scores exhibited a low positive correlation with

depression and anxiety scores (Table 3).

Discussion Unipolar and bipolar patients were enrolled in the study

during their latest depressive episodes. There was no dif-

ference between these two groups in terms of mean num-

ber of depressive episodes experienced. Similarly, no

difference was found between the two groups in terms of

severity of depression and anxiety. Self-esteem was lower

in the bipolar group compared with the unipolar group

(small effect size). These fi ndings suggested that the two

groups were similar in terms of disease severity. Depres-

sive disease onset was later in the unipolar group, while

duration of disease was greater in the bipolar group. This

is an expected fi nding.

Table 3. Pearson correlation analysis between Meta-Cognitions Questionnaire (MCQ) subscales and anxiety, depression and self-esteem scale scores in the bipolar and unipolar depression groups.

Self-esteem Beck depression Beck anxiety

Bipolar depression ( n � 45)

Positive beliefs about worry r � � 0.26 r � 0.33 * r � 0.37 * Negative beliefs about worry concerning

uncontrollability and danger

r � � 0.38 * * r � 0.30 * r � 0.53 * * *

Lack of cognitive confi dence r � � 0.27 r � 0.23 r � 0.32 * Beliefs about the need to control thoughts r � � 0.51 * * * r � 0.34 * r � 0.60 * * * Cognitive self-consciousness r � � 0.15 r � 0.23 r � 0.44 * *

Unipolar depression ( n � 51)

Positive beliefs about worry r � � 0.18 r � 0.13 r � 0.19

Negative beliefs about worry concerning

uncontrollability and danger

r � � 0.43 * * r � 0.28 r � 0.38 * *

Lack of cognitive confi dence r � � 0.25 r � 0.10 r � 0.31 * Beliefs about the need to control thoughts r � � 0.41 r � 0.44 * * r � 0.39 * * Cognitive self-consciousness r � � 0.09 r � 0.08 r � 0.19

* P � 0.05, * * P � 0.01, * * * P � 0.001.

Coeffi cients � 0.30 are shown in bold.

Page 6: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

G. SARISOY ET AL.

6 NORD J PSYCHIATRY·EARLY ONLINE·2013

bipolar depression, metacognitive beliefs about worry can

also be seen. Metacognitive beliefs about worry need to

be focused on in the identifi cation of metacognitive

beliefs in depression patients and in the metacognitive

therapy given them.

Acknowledgments This paper has not received funds from any agency. The

authors do not have an affi liation with or fi nancial inter-

est that might pose a confl ict of interest for this paper.

Declaration of interest The authors report no confl icts of

interest. The authors alone are responsible for the content

and writing of the paper.

References Wells A . Emotional disorders and metacognition: innovative 1. cognitive therapy . Chichester: Wiley; 2000 . Fisher PL , Wells A . Metacognitive therapy for obsessive – 2. compulsive disorder: A case series . J Behav Ther Exp Psychiatry 2008 ; 39 : 117 – 32 . Nolen-Hoeksema S . Ruminative coping with depression. In: 3. Heckhausen J, Dweck CS, editors. Motivation and self regulation across the life span. New York: Cambridge University Press; 1998 . p. 237 – 256 . Brokovec TD , Robinson E , Pruzinsky T , De Prue JA . Preliminary 4. exploration of worry . Some characteristic and processes. Behav Res Ther 1983 ; 21 : 9 – 16 . Wells A , Carter K . Further tests of a cognitive model of 5. generalized anxiety disorder: Metacognitions and worry in GAD, panic disorder, social phobia, depression, and nonpatients . Behav Ther 2001 ; 32 : 85 – 102 . Cartwright-Hatton S , Wells A . Beliefs about worry and intrusions: 6. The Meta-Cognitions Questionnaire and its correlates . J Anxiety Disord 1997 ; 11 : 279 – 96 . Wells A , Cartwright-Hatton S . A short form of the Metacogni-7. tions Questionnaire: Properties of the MCQ-30 . Behav Res Ther 2004 ; 42 : 385 – 96 . Wells A , Papageorgiou C . Relationships between worry, 8. obsessive – compulsive symptoms and meta-cognitive beliefs . Behav Res Ther 1998 ; 36 : 899 – 913 . Myers SG , Wells A . Obsessive – compulsive symptoms: The 9. contribution of metacognition and responsibility . J Anxiety Disord 2005 : 19 : 806 – 17 . Hermans D , Engelen U , Grouwels L , Joos E , Lemmens J , Pieters G . 10. Cognitive confi dence in obsessive – compulsive disorder: Distrusting perception, attention and memory . Behav Res Ther 2008 ; 46 : 98 – 113 . Barahmand U . Meta-cognitive profi les in anxiety disorders . Psychia-11. try Res 2009 ; 169 : 240 – 3 . Moritz S , Peters MJ , Lar ø i F , Lincoln TM . Metacognitive beliefs in 12. obsessive – compulsive patients: A comparison with healthy and schizophrenia participants . Cogn Neuropsychiatry 2010 ; 15 : 531 – 48 . Cucchi M , Bottelli V , Cavadini D , Ricci L , Canca V , Ronchi P 13. et al . An explorative study on metacognition in obsessive – compulsive disorder and panic disorder . Compr Psychiatry 2012 ; 53 : 546 – 53 . Morrison AP , Wells A . A comparison of metacognitions in patients 14. with hallucinations, delusions, panic disorder, and non-patient controls . Behav Res Ther 2003 ; 41 : 251 – 6 . Wells A . Meta-cognition and worry: A cognitive model of general-15. ised anxiety disorder . Behavioral and Cognitive Psychotheraphy 1995 ; 23 : 301 – 20 . Holeva V , Tarrier NT , Wells A . Prevalence and predictors of acute 16. stress disorder and PTSD following road traffi c accidents: Thought control strategies and social support . Behav Ther 2001 ; 32 : 65 – 83 .

sample that worry is correlated with anxiety and depres-

sion while rumination is only correlated with depression.

Barahmand, however, maintains depressive disorder

patients have a greater tendency compared with GAD

and OCD patients to make greater use of worry as a

thought-control strategy in order to control intrusive and

distressing thoughts (11). In the light of these and our

own fi ndings, in addition to metacognitions associated

with depression, it is also important for metacognitions

associated with worry to be evaluated in depression

patients. Lack of cognitive confi dence scores in our bipo-

lar depression patients was higher than those of the

healthy controls. However, we determined no difference

between unipolar and control group scores. In one study

with OCD patients, lack of cognitive confi dence was

correlated, not with severity of OCD, but with depres-

sive symptoms (12). Studies involving larger numbers of

depression patients are needed to investigate the probable

correlation between lack of cognitive confi dence and

depression (particularly bipolar depression).

The second aim of this study was to investigate the rela-

tionship between metacognitions and anxiety, depression

and self-esteem in unipolar and bipolar depression groups.

No studies investigating this were encountered. Negative

beliefs about worry concerning uncontrollability and danger

in the bipolar and unipolar patient groups, and also beliefs

about the need to control thoughts in the bipolar patient

group, were negatively correlated with self-esteem. Meta-

cognitions in both the unipolar and bipolar patient groups

were positively correlated with anxiety and depression lev-

els. It is noteworthy that anxiety level was correlated with

all MCQ subscale scores in the bipolar patient group. One

study with a non-clinical sample reported that negative

metacognitive beliefs about uncontrollability and danger of

worry were a predictor of anxiety and depression indepen-

dently of stressful life events (36). Another study with a

non-clinical sample identifi ed metacognitions as a predictor

of state anxiety (37, 38). Our study fi ndings are important

in showing that metacognitions (concerning worry) are

closely correlated with self-esteem, anxiety and depression

in both groups of depression patients.

The literature contains two different scales evaluating

positive and negative beliefs about ruminations in depres-

sion patients (19, 22). In order to be able to fully evalu-

ate metacognitions in depression patients, an inclusive

scale (as MCQ) evaluating lack of cognitive confi dence,

beliefs about the need to control thoughts and cognitive

self-consciousness is needed in addition to these two

scales. Worry as well as ruminations should be evaluated

in that scale.

Conclusions In conclusion, in addition to rumination-associated meta-

cognitive beliefs that are already known in unipolar and

Page 7: Metacognitive beliefs in unipolar and bipolar depression: A comparative study

METACOGNITIVE BELIEFS IN DEPRESSION

NORD J PSYCHIATRY·EARLY ONLINE·2013 7

Ç uhadaro 32. ğ lu F . Adolesanlarda benlik sayg ı s ı . Uzmanl ı k tezi . Hacettepe Ü niversitesi T ı p Fak ü ltesi, Ankara , 1986 (in Turkish) . Hinkle DE , Wiersma W , Jurs SG . Applied statistics for the 33. behavioral sciences . New York: Houghton Miffl in Company; 1998 . Hong RY . Worry and rumination: Differential associations with 34. anxious and depressive symptoms and coping behavior . Behav Res Ther 2007 ; 45 : 277 – 90 . Hoyer J , Gloster AT , Herzberg PY . Is worry different from rumina-35. tion? Yes, it is more predictive of psychopathology! Psychosoc Med 2009 ; 6 : 1 – 9 . Y ı lmaz AE , Gen ç ö z T , Wells A . The temporal precedence of 36. metacognition in the development of anxiety and depression symptoms in the context of life-stress: A prospective study . J Anxiety Disord 2011 ; 25 : 389 – 96 . Spada MM , Georgiou GA , Wells A . The relationship among 37. metacognitions, attentional control, and state anxiety . Cogn Behav Ther 2010 ; 39 : 64 – 71 . Dragan M , Dragan W Ł , Kononowicz T , Wells A . On the 38. relationship between temperament, metacognition, and anxiety: Independent and mediated effects . Anxiety Stress Coping 2012 ; 25 : 697 – 709 .

G ö khan Sar ı soy, M.D., Assistant Professor, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . Ozan Pazvanto ğ lu, M.D., Assistant Professor, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . Deniz Deniz Ö zturan, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . Naile Dila Ay, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . Tuba Y ı lman, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . Sema Mor, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey . I ş ı l Zabun Korkmaz, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey. Ö mer Faruk Ka ç ar, M.D., Assistant, Psychiatry Department, School of Medicine, Ondokuz Mayis University, Samsun, Turkey .K ü bra G ü m ü ş , Nurse, Health Services Vocational School, Ondokuz Mayis University, Samsun, Turkey.

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