醫工學會July, 2012 第 期6

E-Newsletter

http://www.bmes.org.tw/

Taiwanese Society of Biomedical Engineering

中華民國生物醫學工程學會

●P3

●●P32 研討會訊息

單位介紹:元培科技大學 生物醫學工程學系單位介紹: 財團法人金屬工業研究發展中心

醫療器材及光電設備處P12 JMBE最新論文

●P7 更多醫工動態盡在醫工學會電子報，請即刻閱讀！學會為了嘉惠醫工大家庭，100年4月回復電子報發行，預計每三個月出刊一期，敬請期待，對於本學會 電 子 報 ， 有 任 何 意 見 ， 歡 迎 來 電 指 教(06)2760665

封面圖：元培科技大學

恭賀JMBE： 2011 SCI IF=0.7312012邁向目標1.0前進

恭賀JMBE： 2011 SCI IF=0.7312012邁向目標1.0前進

2012 醫工科技研討會重要時程：開放上傳論文:2012年06月01日開放註冊繳費:2012年08月01日

目錄

最新消息.........................................................................................................1 單位介紹

元培科技大學 生物醫學工程學系……………………..…...…….…3 財團法人金屬工業研究發展中心醫療器材及光電設備處...…….…7

醫工證書動態消息……………………………………..………….……....11 JMBE 最新論文…………………………………………………….……..12 近期研討會相關訊息…………………………………………….………..32 2012 世界醫學物理與生物醫學工程會議參與報告………………….….35

理事長： 蘇芳慶

常務理事兼副理事長： 葉宗仁

常務理事： 王家鍾、婁世亮、張志涵、陳信泰、陳家進

申斯靜、朱湘麟、江青芬、林念游、林峯輝

徐良育、張文濤、張世明、郭士民、陳文斌

陳進富、錢嘉宏、蘇振隆、張 寅

秘書長： 王士豪

副秘書長： 張淑真

常務監事： 徐善慧

監 事： 胡威志、張憲彰、許朝淵、陳天送、黃義侑、蔡育秀

主 編： 張淑真

編 輯 群： 林鼎勝、王家鍾、李佩芳、林惠怡、郭媛琳

醫工學會秘書處：

70101 台南市大學路一號 國立成功大學生物醫學工程系轉醫工學會 TEL: +886-6-2760665 FAX: +886-6-2343270 E-mail: tsbme@conf.ncku.edu.tw

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最新消息

【JMBE 重要訊息: JMBE 2011SCI IF=0.731】 醫工學會期刊Journal of Medical and Biological Engineering (JMBE) 2011年的impact factor (IF) 已上升至0.731，比2010年的IF=0.42，大幅提升了74%。雖然在醫學工程

領域(Biomedical Engineering category)的激烈競爭下，仍在後段班(Q4, 61/72 or 84.7%)，但已脫離底部區，對僅第二年列入SCI排名，實屬難能可貴。JMBE目前在

亞洲地區的生物醫學工程相關期刊排名第一，已超越新加坡、日本及澳洲等出版的

醫學工程相關期刊。其在國內SCI的期刊排名(Country/Category ranking)也由去年的

24/31 (77.4 %)，一舉進步至前半段15/32 (46.9%)，超越國內許多名列SCI多年的生

理、物理、機械或化工等領域期刊。在Scientific Journal Ranking (SJR, SCImago Journal & Country Rank)掛名於台灣自行發行(排除國內期刊委託國際大出版社發行

者)的工程期刊(Engineering Category)，不論IF或SJR等排名皆名列前茅，遙遙領先

國內許多老牌的工程期刊。JMBE目前已是國科會補助的優良期刊，在國科會生醫

科學雜誌之AB表的計分上也有加權分數。感謝國科會的經費贊助，今年預估收稿

量將超過280篇，約有60-70%為國外地區投稿，退稿率(rejection rate)為70%。

目前JMBE的篇數已由原先每年4期32篇，增加至目前的每年6期60篇，但仍供不應

求，2013年將小幅增加篇數，約有一半期刊論文為國內優秀學者發表。明後年的目

標為突破IF=1.0，將面對許多不錯的國際醫工期刊如: Biomedical Engineering Online, Computers in Biology and Medicine, Biomedical Signal Processing and Control

但2012要達到IF=1.0，需有115篇2010-2011的JMBE的論文在2012的SCI期刊論文被

引用，有相當困難度，目前上半年初估大概缺20篇左右。希望國內醫工界先進或後

起之秀，在幫助國內醫工界的國際能見度上，多多引用JMBE最近兩年的期刊論文，

假若您有修訂中或即將接受的SCI期刊，可以引用JMBE的論文，學會可以協助引用

的方式，若需要協助請將您的摘要及題目寄至 jmbe@jason.bme.ncku.edu.tw。

JMBE網址: http://jmbe.bme.ncku.edu.tw/index.php/bme/

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最新消息

【紀念鍾高基教授】 鍾高基教授是我國醫學工程領域的精英，於國立成功大學醫學工程研究所從事教育

研究二十載。鍾教授於 101 年 7 月 1 日辭世，享年 62 歲，本學會謹在此感念鍾高

基教授對醫學工程學術、研究及教育之貢獻。

【恭喜江惠華教授】 恭喜陽明大學醫工所教授、國科會醫工學門召集人江惠華博士，於 101年起擔任行

政院科技會報辦公室執行秘書，統籌科技發展政策，整合跨部會科技發展事務，協

調推動全國整體科技發展。

【重要研討會訊息】 2012 International Symposium on Chemical-Environmental-Biomedical Technology，2012 年化工-環工-醫工技術國際研討會謹訂於 9 月 2‐5 日於成功大學光復校區國際

會議廳舉行，相關消息請參閱網址: http://conf.ncku.edu.tw/iscebt2012/isCEBT 【重要研討會訊息】 2012 醫工科技研討會謹訂於 11 月 17‐18 日於中原大學真知教學大樓舉行，重要時

程如下： 開放上傳論文 2012 年 06 月 01 日 開放註冊繳費 2012 年 08 月 01 日 論文截止收件 2012 年 10 月 01 日 註冊優惠截止 2012 年 10 月 22 日 論文通知接受 2012 年 10 月 15 日 線上註冊截止 2012 年 11 月 12 日 相關投稿及註冊消息請參閱網址：http://bmes2010.xwing.com.tw/2012/art/info/77 【重要活動訊息】 2012 生物醫學工程創意設計、製作競賽活動由中原大學醫療器材推廣中心承辦，

本次活動獎金豐富，所設定之競賽主題，對於學生也是相當難得的訓練機會，敬請

協助多多鼓勵您系/所學生，踴躍組隊參加。

創意實作競賽報名截止日期: 2012-08-15 創意實作競賽報告書收件截止日期: 2012-09-10 公告創意實作競賽報告書初審結果: 2012-09-20 創意製作競賽決賽: 2012-10-26(地點:南部科學園區-高雄園區) 得獎作品展示：2012-11-17~11-18，得獎作品需於 2012 生物醫學工程年會暨醫工科

技研討會會場進行作品展示，並於年會頒發獎牌與獎金。

詳細參賽資格及活動辦法，敬請參閱創意競賽網址：

http://www.2012bmes.create.cycu.edu.tw/

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單位介紹

元培科技大學 生物醫學工程學系 Department of Biomedical Engineering

系所簡介

以人為本、以愛出發 元培科技大學於民國 83 年成立醫學工程科，初期招收日間部二年制專科生，

隨著校務發展、師資擴充與軟硬體設備之提升，醫學工程科於民國 89 年改制為醫

學工程系，開始招收四年制及二年制學院生。民國 96 年更名為「生物醫學工程系」。

民國 101 年成立「福祉科技與工程研究所」。本系設立之宗旨乃為培育具備醫學工

程專業技術之人才，能夠從事醫療儀器與輔具之開發、安裝、維修、保養等工作，

以供國內醫療產業之人力資源需求。希望學生能發揮同理心，以工程科技與生物醫

學為基礎，開啟現代福祉科技與學術整合研究的趨勢，協助醫療品質提升，建構身

心靈無障礙的環境。

系所特色

*成立於民國 83 年，全國技職體系首創生物醫學工程系 *全國技職體系中唯一通過國際工程教育認證(IEET) *課程設計以醫學電子暨資訊學程與生醫材料暨力學學程為主軸發展 *具有連貫性的福祉科技與生物醫學工程課程教育 *擁有全方位的醫工專業實驗室：電子實驗室、微處理實驗室、生醫訊號及資訊處

理實驗室、生醫材料及力學實驗室、專題實驗室、教師研究實驗室

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單位介紹

師資陣容 目前任教於本系計有18位資歷豐富的教師，分別來自國內外生物醫學工程相關領域

之博士學位，9位教師具有醫工師證照，老師專長涵蓋生物醫學工程各領域，搭配

教授多元化課程以符合不同學習興趣與特質學生的需求。

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單位介紹

課程規劃

本系在培育跨領域技術人才，醫學電子、生物力學為發展主軸，輔以生醫資訊和生

醫材料的專業領域，培養兼具工程技術與醫學知識的醫學工程師，成為具有專業素

養與能力、工程與管理兼備及專精於整合系統之生物醫學工程人才。本系課程規劃

以實務理論並重，並依循本校宗旨「健康福祉 服務人群」為依歸，將課程領域劃

分為「醫學電子暨資訊學群」、「生醫材料暨力學學群」二大主軸。 (一) 醫學電子暨資訊學群 發展微小化生理感測技術：以微型感測器搭配簡易設計且具備高效能之生理訊號處

理電路，來量取不同的人體生理訊號為發展目標。同時考量生理感測時所產生的感

測器與人體組織之生物相容性問題，因此生醫材料的應用研究上也有著墨。 嵌入式系統於醫療電子系統之應用：有鑑於目前微處理器與多功能數位訊號處理晶

片的發達，以高效能之微處理器與晶片為核心，以發展高效能系統平台及模組化之

醫療儀器系統。 非侵入式量測技術之開發：此部分將針對現有侵入式診斷技術作一檢討，並逐一發

展相對應的非侵入式或者最少侵入診療技術，以減少受測者的痛苦。 遠距醫療與居家看護之綜合發展：在上述研究成果成型之後，將納入生一資訊學

理，整合智慧型監測及無線式傳測等技術，逐步發展適用於個人居家看護之遠距醫

療技術，以協助個人平日之自我照護與保健，以達成e-health與home-care之目標。 研製系統晶片以多元處理生理訊號：由於本校位於新竹市，鄰近新竹科學工業園

區，竹科竹南基地、國家衛生研究院、以及多所學研單位，因此可佔地利之便，結

合本地雄厚的半導體資源，針對不同的生理訊號發展出微小化的系統晶片(System on a chip)，以替未來小型醫療儀器的發展奠定良好的基礎。 微型醫療儀器系統：結合系統晶片的發展，可進一步研發微型的醫療電子儀器系

統。有別於一班醫療儀器，微型醫療儀器系統可方便個人攜帶並外出使用，除可提

供權時的生理監控與診斷外，尚符合機動性醫療單位的需求，例如緊急救援和居家

護顧系統等。 (二) 生醫材料暨力學學群 生物流體力學的研究：結合生理學、電腦輔助製圖與電腦輔助流力分析等知識，落

實可攜式治療用微流道生醫晶片之理論發展與設計製作。 科技輔具與健康器材的研發：以機電整合技術在復健器材之應用為主要發展項目，

運用從解剖學、功能評估、生物力學與臨床疾病與傷害得來的相關資料，以製作輔

具的各種材料，並依各部分輔具元件設計的原理、目的，適當的運用，以期能夠研

究出更適合、更舒適的輔具與器材。 運動生物力學的研究：藉由人體結構分析、動作行為分析、器材設計分析(包括運

動器材、防護器具、訓練儀器)、環境分析(包括場地、重力場、溫度、濕度、氣流、

水流等項目的測試與分析)，達到預防運動突發性及過度使用之傷害及提高效率及

經濟表現的目的。 智慧型生醫應用材料的開發：以環保節能為原則，以新的製程與改質技術研發智慧

型之結構性與功能性材料，具有感應壓力、溫度、濕度或生化分子等環境訊息產生 化學能、機械能或電能輸出之特性，進而應用於換能器、生物感測器、輔具元件及

藥物制放元件等關鍵零組件之製作。

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單位介紹

福祉科技與工程研究所 配合本系發展方向，本系研究所碩士班課程朝向生醫電子(Bioelectronics)、醫

學資訊(Bilinfor- matics)、生物力學(Biomechanics)、生醫材料(Biomaterial)等四大專

業領域來規劃安排。期望由本所畢業的同學，經由專業課程的訓練，均可具備解決

醫療儀器設計過程中有關生物、醫學或工程問題的能力。在整體課程的設計中強調

學群領域的互補與資源共享，達到培育跨領域技術、具有專業素養與能力及專精於

系統整合之福祉科技與醫學工程人才的目的。綜合上述兩大學群之課程與重點發展

方向之規劃，本系期盼在縱向上，能有效銜接四技之課程，做理論之延伸；在橫向

上，則做技術研發能力之紮根工作，以期順利達成「配合國家發展重點科技及產業

界之需求，培育兼具理論與實務，且能擔當技術開發之醫工專才」之教育目標

學生未來發展

升學 本系學生除可報考國內外醫學工程相關科系研究所外，也可報考電子、電機、資訊、

材料工程及生物科技等研究所。本系畢業生研究所升學率逐年上升，近二年平均升

學率均突破四成，錄取學校包括陽明大學、台科大、北醫等頂尖公、私立大學研究

所，成績亮眼。 就業 本系畢業生可任職國內各醫療院所之醫工部門，各醫療器材廠商、代理商之維修或

行銷部門、或電機、電子、資訊、輔具等產業的相關工作。另一方面，關於公職的

就業機會，則有行政院衛生署、台灣食品藥物管理局(TFDA)、台灣電子檢驗中心

之可從事醫療器材查驗管理相關工作，而法人機構方面則有國家衛生研究院、工研

院醫療器材科技中心等單位提供醫工相關之研發工作機會。 證照/考試 目前國內醫工相關證照有中華民國生物醫學工程學會所認證之醫學工程師、醫療設

備技師或臨床工程師證照等證照。其他相關證照還有勞委會所辦理之電子類國家技

術士檢定證照及財團法人全國認證基金會辦理之 ISO/IEC 系列證照等。

現有學制 □學士班 ■碩士班 ■博士班 □進修學士班 □碩士在職專班

聯絡方式

網址：http://bme.ypu.edu.tw/bin/home.php e-mail：eng@mail.ypu.edu.tw 電話：(03)6102346 傳真：(03)6102347 地址：30015 新竹市元培街 306 號 元培科技大學 生物醫學工程學系

101.07 醫工_____ 7

單位介紹

財團法人金屬工業研究發展中心醫療器材及光電設

備處暨南部生技醫療器材產業聚落發展之介紹

緣起 財團法人金屬工業研究發展中心（以下簡稱本中心）於九十四年起協助南部科

學工業園區管理局，執行連續三年有關高雄園區生技醫療器材產業專區之設立及招

商計畫，透過三年來南部地區產、官、學研、醫界各界資源交流與整合、專區設立

規劃與配置、招商平台建構與互動，至九十六年計畫完成時，其專區知名度與吸引

力已大幅成長。同時，高雄科園區內光電產業亦蓬勃發展，有鑑於此，本中心朝著

多方位發展及協助南部傳統產業升級之考量下，於九十七年正式成立「醫療器材及

光電設備處」並進駐高雄園區服務園區內之廠商。期望透過光電與醫材兩者之結合

能達到相輔相成之效果，能將此技術及研發能量充分運用在醫療器材領域，使高雄

科學園區成為生技醫療、綠能、光電等高科技、高附加價值的產業聚落。 本中心醫電處依高雄科學園區內進駐廠商之屬性及需求，分別設立光電系統

組、複合醫材技術組、醫療器材研發組及醫材及光電產業服務組。期能透過此四大

組別之豐富資源與研發能量進而服務園區內生技醫療器材及光電之業者，更建立起

良好的互動關係，並加以整合週邊產、官、學研及醫界之醫材研發能量，全力配合

園區發展。 南部生技醫療器材產業專區發展之現況

自九十八年度起國科會委由南部科學工業園區管理局推動「南部生技醫療器材

產業聚落發展計畫」。此計畫是以醫療器材產業為核心，整合研究機構、大專院校

與廠商的現有資源，擬定整體發展策略、創造生技醫療器材產業專區之投資誘因、

加強宣傳活動與實際訪廠招商、促進產學合作，以吸引廠商進駐及協助建立以南科

高雄園區為主的醫療器材產業聚落，並輔導南部中小型傳統製造業技術提昇與產品

價值升級、導入臨床醫療人員協助醫療器材產業發展新型醫療器材與技術，期能以

產業聚落吸引國際醫療器材大廠進駐或投資南科廠商，推動高雄園區成為世界級的

醫療器材產業中心。 本計畫於今年（101 年）將邁向第四年為第一期計畫之尾聲，執行四年期間已

注入新台幣約 12 億元經費，未來更期許於政府支持下繼續為園區廠商爭取相關配

合醫材產業發展能量與資金投入。

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單位介紹

目標規劃 高雄園區於現階段目標之規劃，於產品面主要是根據國內外醫療器材成長的趨

勢與國內現有的傳統產業特質，以台灣中小企業所具有精密加工的優勢技術為主要

核心，來發展牙科、骨科、醫用合金等相關植入物與手術醫療器材，並整合國內光

電與軟體資訊已有的基礎，發展牙科骨科使用的醫療雷射、牙科用電腦斷層掃瞄儀

與 3D 精密齒雕機等高階高值的醫療系統，系統的發展除了可提昇產品價值外，

更可以帶動系統整合技術，以培育高級研發專業人員。另外配合社會經濟發展對美

容與整型的需求增加與國內觀光醫療的政策，發展的製造生產核心技術與光電技

術，應用在美容整型的醫療器材開發。 於策略面則是先召集國內臨床專家與醫工專業人才，至現有醫療器材廠商進行

深入訪談與評估，根據評估結果提出技術與產品升級方向與目標，再根據提出的規

劃尋找相關領域專家進行協助。並透過國內各大醫學中心之臨床專業人員及醫療器

材相關專家，講解臨床醫療、醫療器材法規、認證智財與設計製造等相關專業知識，

協助廠商進行人才培訓。 而在廠商輔導方面，首先評估廠商現有技術與資源條件，以協助擬訂產品發展

方向與市場定位，結合相關醫療與工程專家進行產品開發與認證，並安排至國外相

關廠商與展示會參訪，以建立製造廠商與相關臨床人員、專家與國外廠商的 聯繫，期能協助廠商於產品開發前，導入臨床人員在實際執行醫療行為發展出的研

發概念，並將此概念實際實施，以改良現有醫療技術與器材或開發新的醫療技術與

器材；除此之外，更強化廠商實際進駐、租廠房或是租地自建廠房，及輔導廠商申

請 GMP，以加速落實生產製造。

101.07 醫工_____ 9

單位介紹

最後，在市場方面，由於國內市場太小，且對於國外市場的開發缺乏行銷的力

量，加上國際市場領導廠商則以積極研發或併購的方式，來開發新產品或補充現有

產品線的不足，因此計畫辦公室透過國外廠商拜訪及帶領國內醫材廠商參與國際展

會方式，協助廠商建立與國外大廠之聯繫及提高能見度，並爭取這些市場領導廠商

來台設立研發、生產或採購據點，以協助國內廠商技術及產品進一步的提昇。 執行成果

計畫執行至今，已順利替高雄科學園區吸引共計 32 家廠商與 11 家醫學大學及

大學進駐園區，包含：鴻君科技、台植科、全球安聯、科頂工業、成果科技、惠合

再生醫學、皇亮生醫、台灣勝協、先寧電子、岱儀智慧、奧羅瑞、和鑫生技、三本

國際、普生公司、膠原科技、益生生技、京達醫材、康那香、聯合骨科、醫百科技、

喜樂醫材、傑奎科技、普一公司、醫橋科技、大安生技、美萌科技、亞力士、棕茂、

美梭、双美生技、光宇、禾研等，投資金額超過新台幣 40 億元，並引進成功大學、

中山大學、高雄醫學大學、高雄第一科技大學、南台科技大學、台科大、台灣大學、

陽明大學、義守大學、義大醫院、秀傳、台北醫學大學等學研機構進駐設置研發中

心，以及陽明大學衍生公司－華骨科技股份有限公司之進駐，執行效益將逐漸顯

現，並帶動醫療器材產業在南部發展。

101.07 醫工_____ 10

單位介紹

未來展望

於未來的發展目標希望能強化國內外廠商之產業鏈結跨足國際舞台，包括相關

業務活動及國際宣傳、舉辦相關醫療器材廠商之互動與交流會、媒合代理商或通路

商，以共同合作方式，拓展醫療器材產業聚落的共通效益及目標市場，期能以產業

聚落吸引國際醫療器材大廠與園區廠商交流，推動高雄園區成為世界級的醫療器材

產業中心。透過這樣的轉變為足以與其他國家醫材產業競爭之產業，此亦是本中心

未來協助台灣醫材產業升級及轉型的工作重點。 聯絡方式 網 址：http://www.mirdc.org.tw/ 專區網址：http://www.ksmd.org.tw/ E - m a i l：shia@mail.mirdc.org.tw 電 話：(07)695-5298#283 傳 真：(07)695-5927 地 址：82151 高雄市路竹區路科五路 88 號 3 樓

（高雄科學園區第一期標準廠房）

101.07 醫工_____ 11

單位介紹 醫工證書

動態訊息

三種醫工證照考試

本學會將於 2012 年 8 月 4 日(星期六)，假中原大學工學院舉辦「臨床工程師」、

「醫療設備技師」及「醫學工程師」三種證照考試，(報名日期：2012 年 5 月 1 日

至 2012 年 7 月 1 日)，目前報名已截止，統計結果出爐，今年預計有 133 名考生參

加，有關資料網站 http://www.bmes.org.tw/exam_news_infor.php?id=MTI=

今年有幾位考生因為沒有事先詳讀考試簡章(今年已修改規定:要求須為本會有

效會員方能參加考試)亦無來電詢問或試圖彌補資格不全之動作，而最終確定無法

參加考試，還請諸位多多見諒並建議明年可提早準備申請，以免向隅。

以上，若有任何疑問，歡迎隨時與學會秘書處聯繫：

業務承辦人：林惠怡小姐

連絡電話：06-2760665

聯絡地址：70101 台南市大學路一號國立成功大學生物醫學工程系轉醫工學會

101.07 醫工_____ 12

JMBE 最新論文

2012 Vol. 32, No 2 Review: A Critical Overview of Limitations of CFD Modeling in Nasal Airflow Mohammed Zubair, Mohammed Zulkifly Abdullah, Rushdan Ismail, Ibrahim Lutfi Shuaib, Suzina Abdul Hamid, Kamarul Arifin Ahmad Computational fluid dynamics (CFD) modeling of nasal airflow has been carried out by several researchers. Virtual surgical treatment and aerosol deposition studies have also been conducted. However, the appropriateness of such modeling practices with regards to modeling and medical constraints needs careful consideration. The current numerical models for the study of nasal airflow, developed from the scanned images obtained from computed tomography or magnetic resonance imaging, are influenced by postural changes. These models neglect the mucous layer, other vital anatomical features, and nasal cycle effects. CFD studies make numerous assumptions that seriously limit their usefulness. Unless these constraints can be addressed, the interpretation of results from a CFD output cannot be considered as an appropriate definition of the flow behaviour. This review provides a critical overview of the limitations of the CFD modeling of nasal airflow. Some of the limitations and constraints associated with CFD modeling are reviewed and possible studies that could be carried out in the future to ascertain the effect of neglecting these parameters are discussed. This study also proposes a standardisation of the computational modeling procedure, which is necessary for studying airflow inside the nasal cavity.

101.07 醫工_____ 13

JMBE 最新論文

Spheroid Formation from Neural Stem Cells on Chitosan Membranes Shan-hui Hsu, Yilo Lin, Ta-Chiang Lin, Ting-Chen Tseng, Hsing-Ta Lee, Yuan-Ching Liao, Ing-Ming Chiu This study demonstrates neural stem cells forming neurosphere-like three-dimensional adherent spheroids on chitosan membranes. Their state can be maintained for at least fifteen days, during which period the spheroids increase their size and number. After this period, the neural stem cells start to migrate out of the spheroids, which change in size when the culture period is prolonged. It is believed that the spheroid formation on chitosan can maintain the self-renewal and plasticity of neural stem cells for weeks, with differentiation possibly occurring at a later period. The culture of neural stem cells on certain chitosan membranes can be used to purify neural stem cells from a heterogeneous cell population.

101.07 醫工_____ 14

JMBE 最新論文

Implementation of Digital Design and Solid Free-Form Fabrication for Customization of Implants in Trauma Orthopaedics Marie Cronskär, Lars-Erik Rännar, Mikael Bäckström Bone plates for the fixation of complex fractures in proximity to joints often have to be reshaped to follow the bone contour. Good adhesion of the screws in areas where the bone is osteoporotic is also a challenge. One possible solution to these issues is to tailor-make plates by creating a digital three-dimensional model of the fracture from a computed tomography (CT) scan, digitally reducing the fracture, designing a plate, and finally manufacturing it directly from the digital model with solid free-form fabrication (SFF) technology. This study designs a custom plate for a distal tibia fracture, and investigates and refines the procedure from the CT scan to the final implant, with the aim of making it usable in trauma orthopaedics. The bone plate is manufactured using electron beam melting (EBM) technology. The challenges of bone plate design using digitalization and SFF are discussed. The virtual models created by the engineer while digitally reducing the fracture and modeling the plate are valuable for the physician while planning the surgery. A combination of surgery planning and digital plate design improves the surgeon’s preparations and ensures correspondence between the plan and the designed implant. The proposed procedure, with the approximate required time in brackets, includes the separation of bone in the DICOM file (60 min), the reduction of fracture (5-30 min), revision (30 min), modelling of the plate (30-120 min), confirmation (30 min), manufacturing with SFF (10 h), post-processing (60 min), and finally cleaning and sterilization (90 min). The whole procedure requires about three working days.

101.07 醫工_____ 15

JMBE 最新論文

Red Blood Cell Velocity Measurement in Rodent Tumor Model: An in vivo Microscopic Study Wen-Chen Lin, Chih-Chieh Wu, Tzung-Chi Huang, Wen-Chi Lin, Bill Yuan-Chi Chiu, Ren-Shyan Liu, Kang-Ping Lin Blood flow dynamics in microvessels in a small animal tumor model provide important physiological and pathological information. In this study, red blood cell velocity in microvessels distributed near the surface in a rodent tumor model is investigated using an approach based on optical flow estimation. A long-term experiment is performed to observe tumor growth on nude mice and to monitor the variation of blood flow velocity. The blood flow images are acquired using a capillaroscope with a spatial resolution of 1.42 μm and an image sampling rate of 30 frames per second. Frame to frame image registration with mutual information feature matching is used to stabilize images to eliminate the vessel shift that results from regular heartbeats. The blood flow results measured by the optical flow method are compared with visual inspection results to verify accuracy. The blood flow observations focus on the tumor surface of nude mice. Multiple weekly data are acquired from each nude mouse for five weeks after tumor implantation. The average red blood cell velocities of capillaries are measured and calculated at different weeks for each tumor. The distribution of blood flow velocity among all samples ranges from 40 to 350 μm/s. The differences in vessel diameter and blood flow velocity during tumor growth are studied. A significant difference is found between the velocity values at the initial week and the 2nd week. The results suggest that an optical-based method can be used to develop experimental protocols for the numerical simulation of tumor growth. The proposed measurement system may also be useful in many other biotechnological evaluations.

101.07 醫工_____ 16

JMBE 最新論文

Mechanisms Underlying Isovolumic Contraction and Ejection Peaks in Seismocardiogram Morphology Viatcheslav Gurev, Kouhyar Tavakolian, Jason Constantino, Bozena Kaminska, Andrew P. Blaber, Natalia A. Trayanova A three-dimensional (3D) finite element electromechanical model of the heart is employed in simulations of seismocardiograms (SCGs). To simulate SCGs, a previously developed 3D model of ventricular contraction is extended by adding the mechanical interaction of the heart with the chest and internal organs. The proposed model reproduces the major peaks of seismocardiographic signals during the phases of the cardiac cycle. Results indicate that SCGs record the pressure of the heart acting on the ribs. In addition, the model reveals that the rotation of the rib with respect to the heart has a minor effect on seismocardiographic signal morphology during the respiratory cycle. SCGs are obtained from 24 human volunteers and their morphology is analyzed. Experimental results demonstrate that the peak of the maximum acceleration of blood in the aorta occurs at the same time as the global minimum of the SCG. It is confirmed that the first SCG peak after the electrocardiogram R-wave corresponds to aortic valve opening, as determined from the impedance cardiogram (p = 0.92). The simulation results reveal that the SCG peaks corresponding to aortic valve opening and the maximum acceleration of blood in the aorta result from ventricular contraction in the longitudinal direction of the ventricles and a decrease in the dimensions of the ventricles due to the ejection of blood, respectively.

101.07 醫工_____ 17

JMBE 最新論文

An Eye-Gaze Tracking and Human Computer Interface System for People with ALS and Other Locked-in Diseases Shuo Samuel Liu, Andrew Rawicz, Siavash Rezaei, Teng Ma, Cheng Zhang, Kyle Lin, Eion Wu Eye tracking is one of the most natural ways for people with amyotrophic lateral sclerosis and other locked-in and paralysis diseases to communicate. The majority of existing eye-tracking computer input systems use cameras to capture images of the user’s eyes to track pupil movements. Most camera-based systems are expensive and not user-friendly. This paper proposes an eye-tracking system called EyeLive that uses discrete infrared sensors and emitters as the input device. The eye-tracking and calibration algorithms classify eye positions into six categories, namely looking up, looking down, looking left, looking right, looking straight ahead (i.e. middle direction), and eyes closed. A graphical user interface optimized for EyeLive is also developed. It divides the screen into a nine-cell grid and uses a hierarchical selection approach for text input. EyeLive’s hardware, eye-tracking algorithm, calibration, and user interface are compared to those of existing eye-tracking systems. The advantages of the EyeLive system, such as low cost, user friendliness, and eye strain reduction, are discussed. The performance of the system in classifying eye positions is experimentally tested with eight healthy individuals. The results show a 5.6% error rate in classifying eye positions in five directions and a 0% error rate in classifying closed eyes. Additional experiments show that the average typing speed is 1.95 words/min for a novice user and 2.91 words/min for an experienced user. The tradeoffs of lower typing speed versus other advantages comparing to other systems are explained.

101.07 醫工_____ 18

JMBE 最新論文

Fatigue Testing of a New Locking Plate for Hip Fractures Stephen Hunt, Rod Martin, Bryan Woolridge Femoral neck shortening and varus deformity can have a significant effect on functional outcomes in patients with femoral neck fractures, particularly in young trauma patients. This study proposes a locking plate construct to address femoral neck fractures. The biomechanical properties of the locking plate are investigated with a specific focus on fatigue performance. The challenges associated with the development of a standardized pre-clinical testing model are also discussed. The development of a testing strategy and three mechanical tests are described. Each of the testing phases compare the proposed plate construct against the currently accepted gold standard of three cancellous screws. The first phase of biomechanical testing involves cadaveric specimens, which are statically loaded until ultimate failure of the construct. The second phase cyclically loads instrumented synthetic bone substitute samples with hardware installed without compression at the fracture site. The third phase cyclically loads samples with hardware installed with compression at the fracture site. Static testing results indicate that the proposed locking plate construct can withstand significantly higher static loads before failure than can the three cancellous screw technique. Fatigue testing results show that without compression across the fracture site, the samples instrumented with the locking plate construct had a shorter fatigue life than samples instrumented with 3 cancellous screws. With compression across the fracture site, the fatigue performance of the proposed locking plate is equivalent to that of 3 cancellous screws. The results indicate that the proposed locking plate construct for hip fractures has superior static strength and equivalent fatigue life compared to those of 3 cancellous screws. Biomechanical testing results show that compression across the fracture site is critical to the fatigue performance of both constructs. The development of a preclinical testing strategy for trauma products requires an understanding of the intended application of the product, expected modes of failure, and a thorough understanding of the product’s service requirements.

101.07 醫工_____ 19

JMBE 最新論文

Microcoil-array-based Multichannel Transcutaneous Transmission for Implantable Neural Electrical Stimulation Zongxia Mou, Wensheng Hou, Xiaolin Zheng, Jun Zheng, Xiaoying Wu, Yingtao Jiang, Ning Hu, Nan Xia A microcoil-array-based multichannel wireless implantable neural stimulator for power and data transmission is developed. The microcoil array is fabricated using four processing technologies, namely enameled wire, printed circuit board (PCB), flexible printed circuit board (FPC), and 4-layer FPC. The coupling efficiencies of the coils are tested under ideal coupling and with spatial mismatch. The experimental results indicate that the decline of output voltage is less than 15% for all microcoils if the horizontal mismatch is less than 3 mm and the angular mismatch is less than 30°. The results also demonstrate that FPC coils produce a higher output voltage than that produced by PCB coils of equal size. The 4-layer FPC coils produce the highest output voltage for a given coil size. An experimental multichannel transmission device is built with a 2×2 microcoil array. The preliminary results show the feasibility of using a microcoil array to achieve multichannel transcutaneous transmission of neural electrical stimulation.

101.07 醫工_____ 20

JMBE 最新論文

Investigation of Neurochemical Techniques for Assessment of Nerve Regeneration within Polymer Guides Chung-Chia Chen, Chu-Ying Chan, Li-Shu Chen, Fuu-Jen Tsai, Chun-Hsu Yao, Chin-Chuan Tsai, Yueh-Sheng Chen The use of proteins associated with neurite outgrowth, synapse formation, and Schwann cell proliferation as surrogate measures for peripheral nerve regeneration is evaluated. Rat sciatic nerve regeneration across a 10-mm gap in silicone rubber conduits (SRCs), genipin-crosslinked gelatin conduits (GGCs), and porous GGCs (PGGCs) is observed. The axonal growth of regenerated nerves after 8 weeks is determined using light microscopy and computer-based quantitative image analysis. The expressions of axonal growth-associated protein 43 (GAP-43), synaptic protein synapsin I, and transforming growth factor type-β (TGF-β) in regenerated nerves are assessed using Western blot analysis. The nerve regenerates in the SRCs has a larger area and more myelinated axons compared to those in the PGGCs and the GGCs. The levels of GAP-43 and synapsin I, but not TGF-β, are well correlated with axonal growth in the regenerated nerves. These data suggest that SRCs provide a more stable and suitable growth environment for regenerating axons than do PGGCs and GGCs. In addition, GAP-43 and synapsin I may be useful indicators of the status of regenerating axons in bridging conduits.

101.07 醫工_____ 21

JMBE 最新論文

Reducing Abnormal Synergies of Forearm, Elbow, and Shoulder Joints in Stroke Patients with Neuro-rehabilitation Robot Treatment and Assessment Pin-Cheng Kung, Chou-Ching K. Lin, Ming-Shaung Ju, Shu-Min Chen Chronic stroke patients are often unable to control their joint movements independently due to abnormal synergies. In our previous work, three robot-assisted therapy indices (two biomechanical indices and one electromyography assessment) were applied to quantify the abnormal synergies of upper limbs with the aid of a neuro-rehabilitation robot. In this study, these quantitative indices are employed to investigate the time course of abnormal synergies in the affected upper limbs of chronic stroke patients treated with the robot. Eight chronic stroke patients are recruited to perform rectilinear tracking movements in four directions (back-forth, two oblique movements at 45 degrees, and right-left) during robot-assisted treatments for 4 months and 4 months of follow-up. The robot-assisted therapy indices (variation of forearm pronation/supination torque, and co-activation of elbow and shoulder muscles) reveal a significant decrease of abnormal synergies after 4 months of robot-assisted treatment and a slight regression in the following 4 months. Significant recovery is found in motor outcomes evaluated using Brunnstrom stage and Fugl-Meyer assessments. Both the robot-assisted therapy indices and clinical scales indicate modifications in abnormal synergies. The rectilinear tracking movements along the contra-proximal to ipsi-distal directions and the right-left directions are suitable for robot-assisted movement treatment for reducing abnormal synergies.

101.07 醫工_____ 22

JMBE 最新論文

2012 Vol. 32, No 3 Review: Health Care CAD Systems for Breast Microcalcification Cluster Detection Maria Rizzi, Matteo D’Aloia, Beniamino Castagnolo Of all the known cancers, breast cancer is the most widespread cancerous pathology among women. As causes of its onset are till unknown, there are no effective ways to prevent breast cancer. An efficient diagnosis in its early stage can thus give women a better chance of full recovery. Therefore, early detection of breast cancer is the key for reducing the associated morbidity and mortality rates. Mammography is the most effective and reliable method for breast cancer early detection. It is a radiological screening technique which makes the detection of breast lesions possible using low radiation doses. It allows breast cancer diagnosis at a very early stage when disease treatment by suitable therapies for the pathology regression/cure is still effective. In a widespread screening program, it is difficult for radiologists to provide both accurate and uniform evaluation particularly because of the large number of mammograms to be analyzed. Therefore, computer-aided detection (CAD) systems, which automatically detect signs of illness in its early stage, are important and necessary for breast cancer control. They provide a second opinion to help physicians detect abnormalities. Microcalcifications and masses are the two most important indicators of illness malignancy, and their automated detection is very valuable for early breast cancer diagnosis. The high correlation between the appearance of microcalcification clusters and diseases suggests that CAD systems for the automated detection of microcalcification clusters can be very useful and helpful for avoiding misdiagnosis and for early stage cancer detection. The present study summarizes the various methods adopted for microcalcification cluster detection and compares their performance. Moreover, reasons for the adoption of a common public image database as a test bench for CAD systems, motivations for further CAD tool improvements, and the effectiveness of various CAD systems in a clinical environment are given.

101.07 醫工_____ 23

JMBE 最新論文

Estimation of Cell Concentration Using High-Frequency Ultrasonic Backscattering Show-Huie Chen, Yi-Hsun Lin, Wen-Tyng Li, Shyh-Hau Wang, Chih-Chung Huang Cell concentration is a crucial quantity for both clinical diagnostic examinations and cell culture studies. However, typical modalities for cell concentration measurements are either time-consuming or not cost-effective. In the present study, cell concentration is estimated using high-frequency ultrasonic backscattering. Validation tests indicate that the proposed method can differentiate red blood cells (RBCs) of various hematocrits. A 50-MHz ultrasound system with appropriate sensitivity is utilized to estimate cell concentrations from a small volume of RBCs suspended in saline, with hematocrits ranging from 1.66 × 10-4 to 10%, and fibroblasts, with concentrations ranging from 2 × 104 to 128 × 104 cells/mL. The backscatter strength and statistical distribution, characterized by the Nakagami parameter, are calculated from gated signals for quantitatively assessing the samples. Results show that the backscatter strength of RBCs linearly increases with increasing hematocrit level in the hematocrit range of 3 to 10%, which agrees well with results of previous studies. The backscatter strength of RBCS has an exponential relationship with the hematocrit level in the hematocrit range of 1.66 × 10-4 to 3%. The corresponding Nakagami parameter is sensitive to electronic noise as long as the signal-to-noise ratio decreasing follows with the decrease of RBC hematocrits at the concentration lower than 0.85%. The backscatter strength of fibroblasts exponentially increases with increasing fibroblasts concentration, which is consistent with results obtained from typical optical density measurements. A linear relationship, with correlation coefficient of 0.99, between the results of ultrasonic backscattering and those of the optical density measurements is established. High-frequency ultrasonic backscattering can be applied to sensitively estimate the concentrations of small volumes of cells.

101.07 醫工_____ 24

JMBE 最新論文

Blood Cell-free Plasma Separated from Blood Samples with a Cascading Weir-type Microfilter Using Dead-end Filtration Ching-Chou Wu, Ling-Zong Hong, Chun-Ting Ou Separating plasma from blood samples, which is done to prevent red blood cells (RBCs) and hemoglobin from interfering with measurements, is important for blood analysis. In this study, a weir-type microfilter is constructed for separating plasma in capillarity-driven dead-end filtration. Microfilters containing alternating pores and chambers are fabricated with the help of polydimethylsiloxane replicas, which are cast from a photolithographically micromachined master mold. Master molds with three-dimensional features are created via a two-step procedure using SU-8 3000 series negative photoresist. Microfilters with 6-μm-high pores and 100-μm-deep chambers exhibited the best efficiency of plasma separation from whole blood samples with a 20% or lower concentration. The chambers and pores, whose dimensions are larger than those of RBCs, gradually remove RBCs from blood samples by gravity action. This approach can eliminate the clogging of pores. The isolated plasma exhibits little hemolysis, with an index of hemolysis of about 0.09% as calculated using blood hydrodynamics. The cascading weir-type microfilters passively separate plasma and can be easily integrated with an electrochemical-microsensor-containing substrate for in situ on-chip blood analysis.

101.07 醫工_____ 25

JMBE 最新論文

Study of Neural Correlates of Mandarin Tonal Production with Neural Network Model Chao-Min Wu, Tao-Wei Wang In linguistics, Mandarin tone is related to Mandarin word and sentence recognition rates. Neuropsychologically, the neural correlates of Mandarin tonal production remain controversial. The long-range aim of this study is to develop a model for analyzing Mandarin speech production. This study modifies the directions into velocities of articulators (DIVA) model to include tone production to simulate Mandarin tonal production and the resulting brain activation. Simulated brain activities for the production of different vowels with a given tone (/a/-/u/) appear on the motor and pre-motor cortices and the inferior frontal gyrus. The activity for the production of a given vowel with four different Mandarin tones (/a/, /á/, /ã/, and /à/) appears in the motor and pre-motor cortices. These results show that the modified DIVA model can be used to study the neural correlates of Mandarin tonal production.

101.07 醫工_____ 26

JMBE 最新論文

Effect of Upper Extremity Impact Strategy on Energy Distribution Between Elbow Joint and Shoulder Joint in Forward Falls Paul Pei-Hsi Chou, Hsin-Chieh Chen, Hsiu-Hao Hsu, Yen-Po Huang, Tun-Chin Wu, You-Li Chou In a forward fall, the majority of the impact energy is absorbed by the elbow joint and shoulder joint. This study examines the effect of the impact strategy on the energy absorption distribution between the two joints during the impact phase of a forward fall. Twenty healthy young male subjects with an average age of 24 years participated in a series of forward fall experiments. The kinematics and kinetics of the upper extremity and the impact forces at the elbow joint and shoulder joint are investigated for three impact strategies, namely elbow dominant, intermediate, and shoulder dominant. The energy absorption ratio and pain score of the elbow dominant group are significantly lower (Energy absorption ratio: p = 0.011, pain score: p = 0.012) than the corresponding values of the intermediate and shoulder dominant groups. The low energy absorption ratio of the elbow dominant group indicates a more uniform distribution of the impact energy between the elbow joint and the shoulder joint. This implies that elbow flexion provides a beneficial damping effect during impact, and therefore reduces the energy absorbed at the shoulder joint. Overall, the results suggest that the elbow dominant impact strategy is optimal for forward falls. The results can aid the development of an effective impact strategy for minimizing the risk of upper extremity injuries due to forward falls.

101.07 醫工_____ 27

JMBE 最新論文

Heuristic Algorithm for Photoplethysmographic Heart Rate Tracking During Maximal Exercise Test Sonnia María López-Silva, Romano Giannetti, María Luisa Dotor, Juan Pedro Silveira, Dolores Golmayo, Francisco Miguel-Tobal, Amaya Bilbao, Mercedes Galindo, Pilar Martín-Escudero Photoplethysmography (PPG) is a non-invasive optical technique that can be used to quantify the arterial blood pulse rate. Signal corruption by motion artifacts limits the practical accuracy and applicability of instruments for monitoring pulse rate during intense physical exercise. This study develops and validates an algorithm, which is based on linear filtering and frequency-domain and heuristic analyses, for extracting the heart rate from a PPG signal in the presence of severe motion artifacts. The basis of the hearth beat frequency selection is the observed high harmonic content of movement artifact signals with respect to the PPG-derived heartbeat. The algorithm, implemented in an experimental PPG measurement device, is developed by analyzing a set of PPG data recorded from a group of athletes exercising on a treadmill. An extensive set of tests is carried out during maximal exercise tests on a treadmill to validate the proposed algorithm by comparison with a reference electrocardiography measurement system. The Bland-Altman method is used to compare and evaluate PPG signals. The accuracy of the heartbeat measurement is better than ± 6.5 beats per minute (bpm) ( ≤ 4.2 %) even under maximal exercise conditions.

101.07 醫工_____ 28

JMBE 最新論文

Predicting the Intelligibility of Cochlear-implant Vocoded Speech from Objective Quality Measure Fei Chen A reliable measure for predicting the intelligibility of cochlear-implant vocoded speech is desirable as it can be used to guide the development of new speech coding algorithms for cochlear implants. The present study assesses the performance of several speech quality measures in predicting the intelligibility of cochlear-implant vocoded speech (vocoded English and vocoded Mandarin Chinese). The quality measures are analyzed and correlated with the intelligibility scores of vocoded speech obtained from normal‐hearing listeners in three experiments. The perceptual evaluation of speech quality measure (r = 0.91) and the weighted spectral slope measure (r = -0.87) are well correlated with the intelligibility score. The language effect impacts the performance of objective quality measures in predicting the intelligibility of vocoded speech.

101.07 醫工_____ 29

JMBE 最新論文

Effect of Sophora Flavescens Alkaloids on the Proliferation and Migration of Vascular Smooth Muscle Cells and Endothelial Cells Gui-Xue Wang, Huo-Lin Chen, Hong-Yan Jiang, Tie-Ying Yin, Ling-Yan Wu Colorimetric analysis is used to investigate the effect of matrine (a Sophora flavescens alkaloid) concentration on the proliferation and migration of vascular smooth muscle cells (VSMCs) and vascular endothelial cells (VECs) with a flow chamber system under various physiological shear flow rates. After treatment with matrine at concentrations of 0, 0.625, 1.25, 2.5, and 5 mg/ml for 24 hours, the inhibition rates of VSMC proliferation are 0%, 23.62% ( ± 0.44), 49.37% ( ± 0.71), 75.43% ( ± 0.68), and 83.81% ( ± 1.09), respectively, and those of VEC proliferation are 0%, 7.50% ( ± 1.88), 17.47% ( ± 2.50), 26.59% ( ± 5.90), and 34.44% ( ± 0.76), respectively. Statistical analysis indicates that matrine inhibits the proliferation of VSMCs and VECs in a concentration-dependent manner. Matrine in concentrations of 0.625 mg/ml to 5.0 mg/ml can significantly inhibit the migration of VSMCs and VECs under physiological shear flow (P < 0.05).

101.07 醫工_____ 30

JMBE 最新論文

Properties of TTCP/DCPA/CSH Cement Immersed in Hanks’ Solution Jiin-Huey Chern Lin, Sen-Hsiang Hung, Wei-Luen Chen, Chang-Keng Chen, Jing-Wei Lee, Ruey-Mo Lin, Chien-Ping Ju As bone substitute materials, most commonly used calcium phosphates exhibit relatively low bioresorption rates. Most calcium sulfates exhibit relatively low mechanical strength and excessively high dissolution rates. The structure and properties of tetracalcium phosphate (TTCP)/dicalcium phosphate anhydrous (DCPA)/calcium sulfate hemihydrate (CSH) cement immersed in Hanks’ solution are investigated in the present study. Results indicate that this cement has a working time of 6.6 min and setting time of 7.7 min. The maximum compressive strength is obtained when the cement is immersed in Hanks’ solution for 1 day, at which point the TTCP/DCPA-hydroxyapatite (HA) phase transformation has been largely completed. The long-term pH value of the Hanks’ solution wherein the cement is immersed remains between 6 and 7. The HA phase remains the dominant phase throughout the entire 42 days of immersion.

101.07 醫工_____ 31

JMBE 最新論文

Frequency-response-based Wavelet Decomposition for Extracting Children’s Mismatch Negativity Elicited by Uninterrupted Sound Fengyu Cong, Yixiang Huang, Igor Kalyakin, Hong Li, Tiina Huttunen-Scott, Heikki Lyytinen, Tapani Ristaniemi This study uses wavelet decomposition (WLD) to extract mismatch negativity (MMN) from electroencephalogram (EEG) recordings. The proposed method is based on the fact that the frequency responses of WLD conform to the frequency properties of the studied signal. Thus, a suitable wavelet for the decomposition and the appropriate levels for the reconstruction required to extract the desired signal can be selected. The reverse biorthogonal wavelet of the order of 6.8 is suitable for decomposing conventionally averaged EEG recordings of the MMN activity of children elicited by an uninterrupted sound under the oddball paradigm. With seven-level decomposition, the coefficients of the fifth and sixth levels are appropriate for extracting the MMN from the averaged trace. Results show that WLD can be used to extract MMN with much better properties than those of that extracted by the difference wave or an optimal band-pass digital filter. The improved properties mean that the deviant stimuli with larger magnitude deviance in contrast to the standard stimuli can elicit the MMN with a larger peak amplitude and a shorter latency. The proposed method can be used as a preprocessing step for multichannel data processing and for the study of other event-related potentials.

101.07 醫工_____ 32

研討會 訊息

國內研討會：

西門子 2012 年台灣醫學工程研討會--低劑量醫療影像之應用 地點: 蓮潭會館 (高雄市左營區崇德路 801 號)

會議時間: 2012-07-20 9：30~16：30 醫工學會會員可取得輔助學分 5 學分 http://www.bmes.org.tw/seminar_show.php?id=143

2012 第二屆再生醫學材料應用國際研討會(2012 ISOMRM) 地點:台北醫學大學(台北醫學大學杏春樓/教研大樓)

會議時間: 2012-08-29~08-31 http://www.2012isomrm.org.tw/ Local participants: http://www.2012isomrm.org.tw/0602registration.php

2012 中華民國生物醫學工程創意設計、製作競賽 地點: 南部科學園區-高雄園區 (高雄市路竹區)

決賽時間: 2012-10-26 http://www.2012bmes.create.cycu.edu.tw/default.aspx

5th International Symposium on Aero-aqua Bio-Mechanisms (ISABMEC 2012) 地點:福華大飯店 Taipei, Taiwan.

會議時間: 2012-08-25 ~ 2012-08-28 http://www.abmech.org/isabmec2012/ 2012 生物醫學工程科技研討會暨國科會醫學工程學門成果發表會 地點: 中原大學真知教學大樓(醫工學會會員可取得主要學分 20 學分)

會議時間: 2012-11-17 ~ 2012-11-18 網址:http://bmes2010.xwing.com.tw/2012/art/info/77

Genome Informatics Workshop 2012(成大與台灣生物資訊與系統生物學會舉辦) 地點:成大 會議時間: 2012-12-12 ~ 2012-12-14

http://conf.ncku.edu.tw/giw2012/index.php/home

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研討會 訊息

國際研討會：

Toronto'2012: Eleventh AES-ATEMA International Conference on Advances and Trends in Engineering Materials and their Applications. Toronto, Canada. Aug. 6 - Aug. 10, 2012. http://aesatema2012.wordpress.com

The 30th World Congress of Biomedical Laboratory Science. Berlin, Germany. Aug. 18 - Aug. 22, 2012. http://www.ifbls-dvta2012.com

5th International Symposium on Aero-aqua Bio-Mechanisms (ISABMEC 2012). Taipei, Taiwan. Aug. 25 - Aug. 28, 2012. http://www.abmech.org/isabmec2012/

XI International Conference on Nanostructured Materials. Rhodes, Greece. August 26-31, 2012. http://www.bmes.org/aws/BMES/pt/sd/calendar/20089/_PARENT/layout_details/false

2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), San Diego, CA, USA. Aug 28 - Sep 02, 2012. http://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=14633

34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). San Diego, CA, USA. Aug. 28 - Sep. 2, 2012. http://embc2012.embs.org/

8th IFAC Symposium on Biological and Medical Systems. Budapest, Hungary. Aug. 29 - Aug. 31, 2012. http://bms.iit.bme.hu/

2012 Inter. Symposium on Chemical-Environmental-Biomedical Technology. Tainan, Taiwan. Sep. 2 - Sep. 5, 2012. http://conf.ncku.edu.tw/iscebt2012/isCEBT

First Symposium on Spline Functions within ICNAAM 2012. Kos, Greece. Sep. 19 - Sep. 25, 2012. http://www.icnaam.org/

Current issues of diagnosis and treatment of oncogynecology diseases, IvanoFrankivsk, Ukraine. Sep. 27 - Sep. 28, 2012. http://nbscience.com/current-issues-of-diagnosis-and-treatment-of-oncogynecology-diseases/

101.07 醫工_____ 34

研討會 訊息

The 2nd International Workshop on Cyber Applications in Healthcare and Public

Health Protection, Sanya, China. Oct. 10 - Oct. 12, 2012. http://www.cyberc.org/

ISOT 2012 International Symposium on OptoMechatronic Technologies. Paris, France. Oct. 29-31, 2012. http://www.isot2012.org/

Mat2012 - 2nd International Conference on Engineering. Antalya, Turkey. Nov. 22 - Nov. 24, 2012. http://mat2012.akdeniz.edu.tr/en

2012 IEEE-EMBS International Conference on Biomedical Engineering and Sciences, Langkawi, Malaysia. Dec. 17 - Dec. 19, 2012. http://www.myembs.org/index2.php/iecbes2012/index

歡迎會員提供更多研討會相關訊息

101.07 醫工_____ 35

研討會 訊息

2012 世界醫學物理與生物醫學工程會議參與報告

會議經過：

2012 世界醫學物理與生物醫學工程會議(2012 World Congress on Medical Physics and Biomedical Engineering, WC2012)每三年舉辦一次。此次會議由中國

生物醫學工程學會/中國醫學物理學會共同主辦，於 5月 26-31日在北京的Beijing International Convention Center 舉行。它是 International Union of Physical and Engineering Sciences in Medicine (IUPESM) 每三年一次的國際會議，IUPESM 由 International Federation for Medical and Biological Engineering (IFMBE) 和 International Organization for Medical Physics (IOMP)聯合組成。IFMBE 是世界衛

生組織(World Health Organization)和聯合國非政府組織的一員，可經由生物醫學

及臨床工程直接影響世界的健康照護。WC2012 它結合了跨領域的專業，包括

醫學、生物、工程、科技，提供來自全球各地生物醫學工程相關研究的學者專

家學術交流與討論的機會，今來的會議從世界各地國家約兩千五佰位學者專家

與學生參與。本次一連 6 天的議程中除有自由投稿論文發表外，更邀請世界上

不同領域的頂尖學者於會議過程中發表專題演講分 Plenary lecture 和 Invited Lecture，會議之主題包含放射腫瘤(Radiation Oncology)、診斷學影像(Diagnostic Imaging)、輻射劑量與保護(Dosimetry and Radiation Protection)、輻射的生物影響

(Biological Effects of Radiation)、癌症研究與治療之新技術、生醫材料與人工臟

器、生物力學、再生醫學與組織工程、生醫訊號處理、細胞分子工程與生醫物

理、電腦輔助手術/微創介入/內視鏡/影像導引治療、遠距醫療/e-health/醫學資

訊、生物感測器/生物奈米技術/生物微機電、聽覺科學/眼科學/急診醫學/牙科

學、復健醫學/運動醫學/復健工程/義肢、神經工程、醫療器材、臨床工程、生

物醫學工程教育倫理及專業相關論壇等議題。重要邀請講者包括 1991 諾貝爾醫

學獎得主 德國的 Erwin Neher 教授，專題演講 Signals and Signaling Mechanisms in the Central Nervous System。

IFMBE 每年固定藉其轄下的國際研討會，召開國際醫學及生物工程聯盟的

秘書長聯合會議，及各個委員會的年度工作會議。而本年度各國家學會委員會

聯合會議藉 WC2012 舉行。今年將過去之 Secretaries Committee 變更為 Societies Committee，學會委員會會議主要有：各會員國學會之年度工作報告、

聯合合作之議題討論及決議、IFMBE 組織、職務及活動分配、年度國際會議之

舉辦等主要議題。中華民國生物醫學工程學會由蘇理事長、秘書長王士豪教授

和前任學會理事長林康平教授(現任 IFMBE「出版及推廣委員會（publication and publicity committee，PPC）」的委員)代表參加此 IFMBE Societies Committee

101.07 醫工_____ 36

研討會 訊息

Meeting 和 5 月 28 日的 IFMBE General Assembly 及 IFMBE Asian Pacific Working Group 會議。

IFMBE General Assembly 主要變更了 IFMBE Organisation Structure，調整 Administrative Council 之組成成員，Administrative Council 將由 The President , The President-elect, The Secretary General, The Treasurer, The Past President, Four elected members (6 year terms staggered) , Four members, one from each Regional Group of the Council of Societies (3 year terms) , Council of Societies chairperson, Clinical Engineering Division Chairperson, Health Technology Assessment Division Chairperson , IAMBE Chairperson 組成。

台灣學者與學生約有 70 餘人參加。另外，5 月 28 日蘇理事長代表中華民國

生物醫學工程學會參加當日下午 IFMBE 亞太工作小組會議，報告 Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 2014 籌辦情形，

APCMBE 2014 將在台灣台南於兩年後舉行。

心得:

醫工學會王秘書長已連續第五年參加 IFMBE 秘書長聯合工作會議，和

IFMBE 幹部及會員國代表間，已建立情誼。我國生物醫學工程學會與 IFMBE和各會員國間的情誼也更加增進，也增進我國在國際間的能見度與影響力，這

是持續參與 IFMBE 會議的主要收穫。這些能量的累積，也促使我國能舉辦

IFMBE 國際研討會，並持續增進我國生物醫學工程的國際學術地位。同時本學

會也透過組團與會模式，協助學會會員問題、聯絡會員情誼、增進學術交流，

讓與會會員感受到學會的服務熱忱，此模式未來應可以持續推廣。

二十一世紀，生物醫學工程蓬勃發展之際，從事相關領域之研究的學者越

來越多，特別是生物力學、生醫材料，人體組織等課題均與生活息息相關，此

會議在這新興研究領域促進醫學工程內跨領域學者的對話。會議論文應用對象

包括了人體、動物的生物體，研究範圍從軟、硬組織、細胞、分子到基因層級

及所有醫學工程相關研究分析。雖然台灣近年來積極提倡高科技精密生物工

程，雖然其成果與水準仍落後國外許多，也追趕得很辛苦，不過在生物力學及

復健工程方面，台灣不但擁有過去傳統產業的優良技術，更與國內醫學相結合，

近十年來的成果不但可與歐美並駕齊驅，更有過之而無不及的趨勢。國人不該

妄自菲薄，在追求高科技的實驗設備前，更應該充實自己研究分析的能力，許

多已有成果的研究在經過創新的方法，以不同的角度切入分析，常常會有意想

不到的新見解與新發現產生，因此，培養創新的眼光、大膽的嘗試，才是研究

者自我期許應該提升的能力。

101.07 醫工_____ 37

研討會 訊息

會議相關照片

IFMBE Asian Pacific Working Group會議與 IFMBE 現任主席 Ratko Magjarevic 教授合影

IFMBE Asian Pacific Working Group會議與 IFMBE 卸任主席 Herbert Voigt 教授合影

蘇理事長與 IFMBE 卸任主席 Herbert Voigt 教授和 IFMBE Asian Pacific Working Group network fellow 合影

王秘書長與現任主席Ratko Magjarevic教授和 IFMBE 亞太年輕學者合影