IMSVISUALInterna.onalMSVisualSystemConsor.um

PabloVilloslada,MD

WhyIMSVISUAL

•  Clinicalresearchisfrequentlyhamperedbecauselackofstandardiza.on,availabilityofbigprospec.vecohorts,compe.ngprojects,lackofquan.ta.vedatabases,visibility/dissemina.onoreconomicsupport

•  IMSVISUALisanindependentconsor.umdrivenbyacademicandclinicalexpertsinthefieldofvisualsystemsinMSaimedtopromoteresearchinthisfieldandspeedthedevelopmentofbiomarkersandclinicaltrialsforpeoplewithMS

Bo#om-upapproach

Objec.ves

toimprovecare,researchandeduca.oninMSandotherneuroinflammatorydisordersbyadvancingourunderstandingofthevisualsystem.1.  Toimprovepa.entcareinregardtovisualsymptoms2.  Topromoteandfosterresearchofthevisualsystemforthepurposeof

diseasediscoveryinordertofurtherourunderstandingofdiseasemechanisms

3.  Toestablishthevisualsystemasamodelwithinwhichtomonitorneurodegenera.onanddiseaseprogression,aswellasneuroregenera.onandneuroplas.city

4.  Toimproveanddevelopnewtechniquesforassessingthevisualsystem.

CommiSees

ProjectCommi#ee

WorkingCommi#ee

SteeringCommi#ee

Teams

•  MembershipisfreeforeverybodyinterestedinthegoalsofIMSVISUALandwillenableyoutopar.cipateinallIMSVISUALproceedings

•  Currently,morethan20teamsfromUS,Europe,AustraliaandAsia

Alberta

NYU

ChariteDusseldorf

HopkinsNIH

UCSF

Macquarie

IDIBAPSBarcelona SanRafaelle

UT

UCLOxford

UZH

Cleveland

IMSVisualconsorOum

Dusseldorf

Philadelphia

Melbourne

Minneapolis

Harvard

Munchen

UCLA

Toronto

WashingtonU

Prague

Resources

•  Guidelines•  Scien.ficar.cles•  WebsiteandnewsleSers•  Mee.ngs•  Networking•  Specialtygroups•  Dissemina.onandoutreachac.vi.es•  IMSVISUALdatabase

–  HostedatNYU(LauraBalcer)–  RunningonRedCap–  Collec.ngdatasetsfromIMSVISUALteam–  Accessibletoscien.ficprojects–  Launchingin2017

Web

•  Dissemina.on•  News•  Mee.ngs•  Newar.cles•  projects

Results:guidelines,ar.cles

Projects

1.Meta-analysisOpOcNeuriOstrials•  PI:ElenaHMar.nez-Lapiscina.IDIBAPS(UBarcelona)•  Objec.ve:toiden.fythemostinforma.vevariables,clinicaloutcomes,.mefrom

onsetand.meofassessmentinONtrials

2.TheInnerNuclearLayerininflammaOonandimmunomodulatorytherapyinMS•  PI:AxelPetzold.UniversityCollegeofLondon•  Objec.ve:toassessthechangesofINLrelatedwithre.nainflamma.onandits

predic.vevalueinresponsetotherapy

3.CROCTINO:CollaboraOveProjectonReOnalOCTinNeuromyeliOsOpOca•  PI:FriedemannPaul.ChariteUniversity,Berlin•  Objec.ve:Toiden.fydis.nctpaSernsofre.naldamageinNMOusingajoint

database

Mee.ngs

•  ACTRIMS•  ECTRIMS•  AAN•  EUPON•  SpecificIMSVisualmee.ngs

•  Pending:EUNOS,NANOS,ARVO,SfN

Challenges

•  Economicsupport•  EachteamandPIneedtocompeteforpromo.onatitscenter•  Prospec.vecohortswithdifferentassessmentsandquali.es•  Compe..onwithmul.plenetworks,consor.ums,projects,technologies,etc.•  Timeandmoneyisverylimited

Butthebenefitswouldoutperformsuchchallenges!